association	dataset	threshold value	standardized value
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20508
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4951
Alzheimer's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53827
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47158
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60628
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16798
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34393
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93817
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.61264
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11987
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.1032
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155830_1_v_0_fkbp5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35208
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62736
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82981
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.03103
yy1_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.147465
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46211
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95065
RCM1	DepMap CRISPR Gene Dependency	1.0	2.17087
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50161
K562_Resveratrol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163036
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22453
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.840682
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5186-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterus-endothelial cell of lymphatic vessel	Tabula Sapiens Gene-Cell Associations	1.0	0.593286
STK17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14749
GSE206870,GSE206872_3_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16627
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.280082
Lung adenocarcinoma_LUAD_TCGA-78-7537-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cultured	GeneRIF Biological Term Annotations	1.0	null
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75949
Red Cell Distribution Width Determination	DisGeNET Gene-Phenotype Associations	1.0	null
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88252
Perturb_9132_KD_Epas1_SRP049514	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.70796
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04642
K562_Hesperadin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013582
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.751
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28806
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76327
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.00807
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23738
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0599
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55097
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874865
Mild cognitive impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18516
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22436
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051375
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850981
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65327
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24189
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27023
dilated liver sinusoidal space	MGI Mouse Phenotype Associations 2023	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17243
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10698
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02517
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE110038,GSE133995_3_v_0_hic1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16215
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.433
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06732
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21938
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.924
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861381
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892817
THBS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65662
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Rdw - Red Blood Cell Distribution Width Result	DisGeNET Gene-Phenotype Associations	1.0	null
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0561
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34263
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Vesicle tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.81
KIT_activemutant_55_GSE17743	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.56163
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.36888
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07187
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94762
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66097
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20225
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11811
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0489
cell cortex part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44318
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00956
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.57745
Systolic Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4141_KO_Apoe_SRP131850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.72081
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27314
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909217
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51809
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45953
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.53458
LS123	CCLE Cell Line Gene CNV Profiles	1.0	1.47784
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06382
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9381
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.834979
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
White Blood Cell Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal tooth morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06808
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914534
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58437
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRPK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10464
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15389
PMC8185471-mmc6.xlsx-up-_and_downregulated_genes-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_shared_FO_and_FC_regions_respectively_Related_to_Figure_6_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.07992
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80777
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0552
Alzheimer's disease or HDL levels (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	9.7
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08276
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SPRYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43304
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.618556
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49058
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96793
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967027
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055318
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Skin mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02901
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41483
SUZ12	ChEA Transcription Factor Targets	1.0	null
NCI-H250	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60861
protein complex localization	GO Biological Process Annotations 2015	1.0	null
lateonset	GeneRIF Biological Term Annotations	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.933745
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.03444
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879504
C-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42214
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.7691
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD2	ChEA Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
KDM4A	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17903
NCIH2087	CCLE Cell Line Gene CNV Profiles	-1.0	-2.64442
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38891
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15774
decreased heart weight	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4795-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877271
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Vascular endothelial cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0307
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57336
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP3	DepMap CRISPR Gene Dependency	1.0	2.68082
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10403
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856299
Perturb_10895_KO_Jnk2_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.19511
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.13711
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34048
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0287
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.03312
USF1	ENCODE Transcription Factor Targets	1.0	null
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2199
CLPP_KO_GSE40207_396_mouse_Muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormal embryo size	IMPC Knockout Mouse Phenotypes	1.0	null
K562_SRT3025 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192887
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.40907
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74354
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.01
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863771
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Amyloid plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99763
Fetal Death	CTD Gene-Disease Associations	1.0	1.18093
2537_EIF2B3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.742585
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54J-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32581
inferior temporal gyrus, right, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.878313
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62515
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
northern	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55801
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0523
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.945811
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58474
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17593
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09988
vegf	GeneRIF Biological Term Annotations	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97431
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19508
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26616
Perturb_12881_KO_Mof_SRP073926	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.62565
vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Alzheimer disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928417
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Alzheimer's disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93461
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22724
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63688
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33242
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73724
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899535
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2181
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938706
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.86743
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.055
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
impaired glucose tolerance	MGI Mouse Phenotype Associations 2023	1.0	null
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22455
COA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40284
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01651
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03234
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67008
Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5027
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22068
GCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01919
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03846
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7973
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58763
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
Body mass index x sex x age interaction (4df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08895
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75H-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.834979
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23147
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.720758
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051114
EFE184	CCLE Cell Line Gene Expression Profiles	1.0	1.53328
K562_Tranylcypromine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227556
Oligohydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
K562_Linifanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210881
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06547
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03258
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50145
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02851
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89229
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09475
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17108
K562_Givinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166711
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01717
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842424
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47328
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
polymorphism	GeneRIF Biological Term Annotations	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907959
7607_RUVBL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.64746
496100633_TCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06191
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24615
MAP1LC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3682
Acute Myeloid Leukemia_LAML_TCGA-AB-2994-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95926
Perturb_6534_KD_Cd80_SRP338134	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961886
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.3839
CDK4_knockdown_143_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.26431
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53264
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.1214
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.38923
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8657
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90878
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193588_1_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	1.79288
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78007
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12609
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.57166
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52349
Fascia dentata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
Trachea-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.258862
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67586
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47705
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	1.88099
Intelligence Tests	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42171
TM9SF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86216
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881154
MMP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10705
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10634
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
NPIPB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81265
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04869
Posterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
K562_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162845
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21648
MXD3_02_83	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59683
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14988
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83719
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4824-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33958
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66315
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.46645
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03882
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29071
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45584
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33297
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15564
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05303
DU145	DepMap CRISPR Gene Dependency	1.0	3.49005
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, dorsal zone, layer 6	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46458
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12159
K562_JQ1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156859
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6274_PHAX_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.579527
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841265
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19957
Serum uric acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199081_0_v_1_insr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18444
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995053
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NTRK2_drugactivation_66_GSE20358	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.91677
GSE213746_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921057
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18259
abnormal incisor morphology	MPO Gene-Phenotype Associations	1.0	null
Platelet distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	7.90458
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.887199
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85792
496100379_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77852
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893345
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1903
18614019-TableS4d	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30303
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.43801
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.598451
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07423
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960156
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
NCI-H1299	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956875
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.34174
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07624
SOX11_DEPLETION_GDS4801_326_human_Z138 mantle cell lymphoma (MCL) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
K562_Tucidinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182007
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormal tooth morphology	MPO Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16657
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.37722
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24074
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63009
lingual gyrus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53451
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05352
superior parietal lobule, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876127
K562_Sodium Phenylbutyrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0290309
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944658
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0421
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibrillar center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.051
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-7498-01A-12R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64301
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1598
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02498
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18944
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95268
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896347
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.309838
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10605_KO_Abcc9_SRP132855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.1442
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836025
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20609
K562_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168128
PMC10828500-41467_2024_44701_MOESM4_ESM.xlsx-ST12-Unnamed_7_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.677
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59473
GTEX-P78B-2526-SM-3P5ZY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927077
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GTEX-S32W-1626-SM-4AD6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16206
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.909368
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.25682
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Cyclocytidine HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0228193
ATP6V1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02971
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78687
cell cortex part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.300682
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29718
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45783
White blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27143
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.3296
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03279
AGS	CCLE Cell Line Gene CNV Profiles	1.0	1.45234
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993211
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838176
hsa-miR-3674	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0809
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89479
Pancytopenia	DisGeNET Gene-Disease Associations	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07371
Red Blood Cell Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Rmz	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
7690_SCD_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.76888
protein binding	GO Molecular Function Annotations 2015	1.0	null
GSE138024_2_v_3_rgs4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Blood Basophil Count (Lab Test)	DisGeNET Gene-Phenotype Associations	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
K562_Motesanib Diphosphate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196457
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97164
increased circulating serum albumin level	MGI Mouse Phenotype Associations 2023	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	3.88316
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42295
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947616
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07915
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.54488
K562_Daphnetin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0201491
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13045
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE211286_1_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201866
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76753
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.84227
Pick's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00942
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987395
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.443
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991349
Thymus-vein endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	6.18651
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3246
MED19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16875
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17211
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10547
Dandy-Walker Syndrome	DisGeNET Gene-Disease Associations	1.0	null
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11882
Brain Lower Grade Glioma_LGG_TCGA-DU-5852-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.17254
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883169
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31005
Perturb_4614_KD_Etv5_SRP231452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.41666
Renal Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935883
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
decreased heart weight	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_4606_KD_H2A.Z_SRP345495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.4089
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
1079_C2ORF68_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.619939
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10809
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68054
4940_MED18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.522153
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JK1	CCLE Cell Line Gene Expression Profiles	1.0	1.70508
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.14491
abnormal placenta morphology	MGI Mouse Phenotype Associations 2023	1.0	null
RMUGS	CCLE Cell Line Gene CNV Profiles	1.0	1.5663
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42395
DIFI	DepMap CRISPR Gene Dependency	1.0	2.77195
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.394
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09732
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	1.88099
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903473
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21205
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1545
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
K562_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199772
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04209
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46369
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
appendix	HPA Tissue Protein Expression Profiles	-1.0	-1.22222
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17364
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64247
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874274
K562_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148409
Granulocyte Count	DisGeNET Gene-Phenotype Associations	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053395
LNCAPCLONEFGC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97745
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8503-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58627
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2045_KO_ZRSR2_SRP050493	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.9663
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29045
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10484
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883169
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31599
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	3.14199
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99351
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947145
abnormal head morphology	MPO Gene-Phenotype Associations	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944658
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24426
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15227
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995589
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10068
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02285
MSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
abnormal craniofacial morphology	MPO Gene-Phenotype Associations	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06713
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38394
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
D502MG	DepMap CRISPR Gene Dependency	1.0	5.88087
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14066
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82375
P31FUJ	DepMap CRISPR Gene Dependency	1.0	3.72689
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.82704
hsa-miR-4425	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
metaanalysis	GeneRIF Biological Term Annotations	1.0	null
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15538
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63522
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3349-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66534
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.11277
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
6792_PRPF19_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.553705
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01202
OPM1	CCLE Cell Line Gene CNV Profiles	1.0	1.81851
K562_Baricitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0307205
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050666
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.864804
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.68481
COACH syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870662
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.929844
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874251
SUDHL1	DepMap CRISPR Gene Dependency	1.0	3.2575
TXNDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41144
protein complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57743
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3869
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5107_OE_Yy1_SRP281855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51321
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09629
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79855
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9831
H3K27me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TP53INP2_KO_GSE54917_384_mouse_Quadriceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H6PD_KO_GDS3195_602_mouse_Skeletal muscle - Soleus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S32W-1526-SM-4AD6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17589
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09113
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955291
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1722
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NL-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
6416_PLBD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.736386
Anhydramnios	DisGeNET Gene-Disease Associations	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04516
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25945
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8CQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.951705
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842804
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27484
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21016
7607_RUVBL1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.551048
icSARA deltaORF6_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92497
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06076
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.55796
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71534
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849727
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14993
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_4741_KD_Mettl3_SRP354177	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4583
GSE110440_1_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	1.84121
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10476
nicotine_myzus persicae_gpl9470_gse18658	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HT1376	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55017
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872532
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41832
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883169
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.834979
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.078607
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
6720_PRDM10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.772478
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU1076	CCLE Cell Line Gene Expression Profiles	1.0	1.48503
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-3.04286
REST_01_211	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.92923
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828642
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88369
K562_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146042
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879043
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942413
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10504
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lewy body dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24233
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828358
hsa-miR-3619-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
5658_NFYC_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.568907
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83946
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33241
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12374
hsa-miR-3170	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Pituitary hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.667
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25679
GTEX-S7SF-0826-SM-4AD4W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26082
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910942
alzheimers	GeneRIF Biological Term Annotations	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.64659
localization	GO Biological Process Annotations 2015	1.0	null
DSTYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72447
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.635135
K562_UNC0379_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170429
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70499
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36229
dorsomedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28255
Exudative Age-Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
3916_HOXC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.06713
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37595
r5 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55607
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.834979
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Quantitative traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3808
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.080672
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52929
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979811
7422_RPAP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.674749
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13448
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Orofaciodigital syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86346
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35734
16498405-TableS10	GeneSigDB Published Gene Signatures	1.0	null
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16548
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14046
superior frontal gyrus, right, medial bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07372
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89229
GSE152432_9_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11583
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01444
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Aurora A Inhibitor I_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0303585
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880062
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843782
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2949
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826265
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
COQ8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42339
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.22064
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85418
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18343
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913658
Perturb_5371_KO_Dcaf11_SRP201454	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.52184
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	2.69927
DNAAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52025
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6870-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19749
cellular process	GO Biological Process Annotations 2015	1.0	null
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.890006
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26534
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1299	DepMap CRISPR Gene Dependency	1.0	2.85011
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-X8HC-0226-SM-4E3K1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87505
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11771
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17352
7505_RPS16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.571202
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09335
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
planum polare, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944779
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.738528
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20906
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00769
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32101
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84994
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1773
Perturb_6338_KO_Crif1_SRP259100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.08656
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1226-SM-4BRUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5637
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28865
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20225
EGR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95212
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.735433
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28742
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04946
SRPK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45158
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.857185
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40286
SNU738	DepMap CRISPR Gene Dependency	1.0	3.3333
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33242
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15804
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OW-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31318
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83504
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21634
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3818
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5121-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62177
RI1	CCLE Cell Line Gene CNV Profiles	1.0	1.57049
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03903
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7102-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54271
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17882
Adrenocortical carcinoma_ACC_TCGA-OR-A5K1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942995
6880_PSME3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.789262
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	2.36391
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17106
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5399
K562_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0236329
Lung squamous cell carcinoma_LUSC_TCGA-43-2576-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_6_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular localization	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87342
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
9587_UMPS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.634292
Acute Myeloid Leukemia_LAML_TCGA-AB-2841-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CISD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65229
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36693
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.813749
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07294
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21849
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61902
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883169
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827025
K562_Obatoclax Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018367
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00056
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.73203
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.364
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
GTEX-Q734-1426-SM-48TZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877531
OAW-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842757
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87302
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851888
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
K562_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153386
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85409
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966429
NCIH2452	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76588
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21745
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
G361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37414
TENM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63785
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.9185
POU5F1-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7313
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.948
ALKBH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22477
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07471
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01739
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1106
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00669
Pancreatic alpha cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15118
4043_IFITM3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.533279
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891889
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48463
abnormal placental labyrinth vasculature morphology	MGI Mouse Phenotype Associations 2023	1.0	null
cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.285138
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12796
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4148
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862217
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1238
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
TP63	ChEA Transcription Factor Targets	1.0	null
K562_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0116567
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865801
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
MFE280	CCLE Cell Line Gene Expression Profiles	1.0	1.77055
Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825451
chr19_45212422_T_C_b38	GTEx eQTL 2025	1.0	3.12905
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Regio parietalis capitis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
K562_GSK-LSD1 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134022
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914132
NCIH2170	CCLE Cell Line Gene CNV Profiles	1.0	1.5261
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42971
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59046
WAOSEL	DepMap CRISPR Gene Dependency	1.0	3.07441
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SFXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71273
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51965
K562_Fluorouracil_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167086
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16496
Perturb_17773_OE_Tgfb1_SRP325964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.35472
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06372
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.617868
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60452
Perturb_6517_KO_Ccr2_SRP297809	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.6074
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.63907
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Rucaparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191853
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00769
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833346
CZIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36852
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1681
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70724
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0304
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-139-ETV3L_ETV3L	Rummagene Transcription Factor Associations 2026	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902367
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04041
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08226
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53133
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.865663
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Meckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
2114_DDX27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.523252
SNCA_KO_GDS4153_530_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05762
MAX	ENCODE Transcription Factor Targets	1.0	null
K562_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129425
Perturb_60_KO_Pabpn1l_SRP226170	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74303
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17211
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21171
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41657
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
8216_SNRNP200_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.581651
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4186
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52375
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070634
ASPC1	DepMap CRISPR Gene Dependency	1.0	3.41423
Uric Acid Measurement (Procedure)	DisGeNET Gene-Phenotype Associations	1.0	null
STON1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02822
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.941398
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989294
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2577
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02828
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884201
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32584
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933936
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3121
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951179
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16126
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900794
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70724
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.15526
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4123
NTRK3_drugactivation_67_GSE20358	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.91677
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54608
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02673
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, nose, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22541
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01048
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13977
abnormal embryo size	MGI Mouse Phenotype Associations 2023	1.0	null
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.851554
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40351
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856282
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12807
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944376
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57234
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE202434,GSE202438_2_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84137
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.04
GSE145249_0_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860786
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22128
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82467
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60924
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV2-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34883
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855868
K562_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170779
K562_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226928
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24804
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45851
KDM5A	ENCODE Transcription Factor Targets	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22754
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050667
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89229
JHH4	DepMap CRISPR Gene Dependency	1.0	3.2361
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50016
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963959
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_65_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.8041
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08777
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.03236
CAMA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5352_KO_Dux_SRP201141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.11098
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Ensembl_ID_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCEA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0414
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80479
GSE162688_3_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01519
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16542
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170692
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.88707
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994135
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31332
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0771
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9731
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03336
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_NM-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13469
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80486
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00669
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4514
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.52817
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110937
K562_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189473
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60452
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2116
Cystic Fibrosis_Lung_GSE3100	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.69058
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40218
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824838
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19627
SPIN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22069
all	GWASdb SNP-Phenotype Associations	1.0	0.034521
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.834979
HEL	CCLE Cell Line Gene Expression Profiles	1.0	1.5476
K562_Abexinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0371554
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921565
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11615
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20106
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6466
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8198
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894745
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916345
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40351
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86695
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1389
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8571
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09188
PMC7203476-Table_3.XLSX-Sheet1-GV_MI_overlap_227_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
ONS76	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55686
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3969
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2753
Lung adenocarcinoma_LUAD_TCGA-78-7161-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A8S6-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.034628
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45263
other	GAD High Level Gene-Disease Associations	1.0	0.295739
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891228
HOP62	CCLE Cell Line Gene CNV Profiles	1.0	2.60313
Lung adenocarcinoma_LUAD_TCGA-44-2665-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8914
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922687
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93624
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.68617
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.045286
NCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39373
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976311
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860955
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
4957_MED7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.595619
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6888893-41422_2019_228_MOESM9_ESM.xlsx-DEGs_of_HEC_aEC_RUNX1-aEC_CXCR4__genes_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828358
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39642
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07956
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
hsa-miR-5095	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_KW-2449_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0235169
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal incisor morphology	IMPC Knockout Mouse Phenotypes	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851831
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2785
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39979
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40241
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.834979
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871104
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24052
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88651
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4593_LIN52_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.604992
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1139
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19869
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.800953
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83225
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26152
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882942
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62674
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07618
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05869
Memory Disorders	CTD Gene-Disease Associations	1.0	1.0869
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
susceptibility	GeneRIF Biological Term Annotations	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73481
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.917
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE169205_0_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33242
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Parental longevity (father's attained age)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5184-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22197
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.75694
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948883
increased circulating iron level	MGI Mouse Phenotype Associations 2023	1.0	null
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49565
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF2AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78716
EGR1	ChEA Transcription Factor Targets	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
TE10	CCLE Cell Line Gene Expression Profiles	1.0	1.39101
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05493
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05325
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.955146
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61087
D-245MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27296
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64007
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	1.82011
H3K9me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893199
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22005
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
K562	CCLE Cell Line Gene Expression Profiles	1.0	2.25282
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838737
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03111
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
5677_NIPBL_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.511084
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32816
binding	GO Molecular Function Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4671
16498405-TableS5	GeneSigDB Published Gene Signatures	1.0	null
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08902
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	1.0	1.46194
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06123
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01195
K562_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189805
exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.05842
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SW626	DepMap CRISPR Gene Dependency	1.0	4.8546
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13039_KD_Tardbp_SRP314028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.0555
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.881095
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889262
Platelet Mean Volume Determination (Procedure)	DisGeNET Gene-Phenotype Associations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2481
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19448
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.162446
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12773
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47237
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6479
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.080672
Bone Marrow Hypocellularity	DisGeNET Gene-Phenotype Associations	1.0	null
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
BICR16	DepMap CRISPR Gene Dependency	1.0	2.89996
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06742
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56065
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882181
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92072
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38996
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72143
Perturb_1701_OE_CLK3_SRP128920	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904153
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5693-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5754-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal snout morphology	MPO Gene-Phenotype Associations	1.0	null
ESYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18786
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
TMEM214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8733
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.903048
K562_Amisulpride_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143569
K562_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184099
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48724
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Platelet Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Normoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78903
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31049
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47084
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27832
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_GSK-LSD1 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151849
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23724
MAP4K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36521
4696_LSM6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.579802
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16739
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.792
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.7926
CHDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00541
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31252
Lung adenocarcinoma_LUAD_TCGA-78-7159-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4152_INTS7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.512797
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034609
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85877
ICC12	DepMap CRISPR Gene Dependency	1.0	2.47947
GSE207787_1_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902885
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1287
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12115
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09487
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.2106
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
2977_FASTKD2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.54705
abnormal incisor morphology	MGI Mouse Phenotype Associations 2023	1.0	null
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72532
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45145
K562_Entinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181344
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02354
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13445
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00769
7827_SET_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.93354
brain	HPA Tissue Gene Expression Profiles	-1.0	-2.05947
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FP-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS299	DepMap CRISPR Gene Dependency	1.0	4.6333
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54019
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.25272
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60447
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44035
Tertiary granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.489
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891854
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940245
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31517
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909966
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54673
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46192
2765_ETV5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.522446
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150496
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.22222
INS-1 823/13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.07469
3570_GTF2E2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.563593
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10876
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02826
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
endothelial	GeneRIF Biological Term Annotations	1.0	null
Heel bone mineral density	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40399
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042446
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	1.25769
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87213
assesses	GeneRIF Biological Term Annotations	1.0	null
Exocyst complex component Sec6	InterPro Predicted Protein Domain Annotations	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32422
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.03218
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15935
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879343
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27172
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18833
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04638
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.546754
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0153
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.06982
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.33986
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04978
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44717
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845451
kidney	HPA Tissue Gene Expression Profiles	1.0	1.56685
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991279
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24615
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938187
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68714
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
GSE113221,GSE113968_4_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35345
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02197
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09008
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13037_KO_Pcgf1/Pcgf6_SRP269225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.84606
GSE196671_5_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREBBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3174
IGF1R_druginhibition_46_GSE14024	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.79561
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14796
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976212
ZNF98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76782
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02112
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37152
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.782396
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13064
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41325
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976105
cell cortex part	GO Cellular Component Annotations 2015	1.0	null
cell cortex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
major	GeneRIF Biological Term Annotations	1.0	null
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.692
increased circulating iron level	IMPC Knockout Mouse Phenotypes	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9727
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3242
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08718
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.21105
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-1226-SM-3P61F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935242
ZNF600	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03693
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81775
K562_TGX-221_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155027
Anterior pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37469
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833619
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.175
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08163
prostate	HPA Tissue Protein Expression Profiles	-1.0	-1.22222
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.1338
hsa-miR-4291	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
GTF2H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4971
chinese	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47118
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40395
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.87861
K562_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203067
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56649
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75915
K562_Thalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148163
Body mass index x age interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13027
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
K562_Raltitrexed_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0276605
Kidney renal clear cell carcinoma_KIRC_TCGA-GK-A6C7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15883
abnormal skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050577
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10974
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8508
K562_Cyclocytidine HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207828
K562_Entinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0208099
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.27083
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897575
NCIH647	CCLE Cell Line Gene CNV Profiles	1.0	2.09585
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38071
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25685
MFE319	CCLE Cell Line Gene Expression Profiles	1.0	2.55997
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01414
Advanced age-related macular degeneration	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
exocyst	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.911541
TIG3TD	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60465
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13871
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80772
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3246
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2883
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02879
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33903
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76187
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017183
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63932
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972737
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01479
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96283
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34504
Lung adenocarcinoma_LUAD_TCGA-55-8299-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	3.57348
hsa-miR-3135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03704
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70163
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.995773
Perturb_15010_KO_Eed_SRP365240	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.2769
Pancreas-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	6.20323
SKBR3	DepMap CRISPR Gene Dependency	1.0	3.98846
K562_Altretamine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151766
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32904
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08746
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06382
K562_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0205367
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I7-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
K562_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127937
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8502
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OU-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal snout morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953443
alzheimer's disease	GAD Gene-Disease Associations	1.0	null
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9426
5022_MFN2_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.712703
Vascular dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	2.48865
KMS20	DepMap CRISPR Gene Dependency	1.0	3.0045
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-2.689
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87299
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02873
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70682
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00205
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.64034
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
estradiol_homo sapiens_gpl1225_gse1486	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.14644
6274_PHAX_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.61514
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26765
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09118
HPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19574
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08037
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26078
Hypertrophy	CTD Gene-Disease Associations	1.0	1.08055
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45367
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929313
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51582
han	GeneRIF Biological Term Annotations	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849577
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.8644
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.0919
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-99-8028-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_14_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.929233
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869595
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88225
ZNF598	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02195
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11459
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.921768
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4064
SPINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3235
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04365
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37144
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77234
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31241
Perturb_56_OE_Pias4_SRP183477	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.1439
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35055
hsa-miR-4437	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23695
Perturb_99_KD_Dis3l2_SRP318863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.8323
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36075
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.4337
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3573
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3195_KO_Poldip2_SRP302743	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.07259
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73333
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.25406
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.509
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A878-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905231
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02963
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.583
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920578
NOTCH1_Deficiency_GDS2848_635_mouse_Hair follicles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02245
exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.84791
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7737
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11122
HS729	DepMap CRISPR Gene Dependency	1.0	2.15105
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36473
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49529
4953_MED30_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.513277
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4798
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47045
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7043
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30087
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51945
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943576
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10634
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3552
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01674
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83138
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928345
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4957
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893301
migration	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238108
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22635
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77099
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.33096
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22428
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.249
Liver-endothelial cell of hepatic sinusoid	Tabula Sapiens Gene-Cell Associations	1.0	0.835742
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36955
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829673
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873788
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87184
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.33731
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7409-01A-31R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998152
HOXA1_01_110	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.47142
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13907
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49098
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.898709
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5007654-srep32566-s2.xls-DISEASE_GENE-POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
exocytosis	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28841
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.79463
Perturb_5582_KO_RELA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.17142
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
Alzheimer's disease or family history of Alzheimer's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.1699
SMAD3	ChEA Transcription Factor Targets	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41046
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	1.68665
2893_TAFA2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.63606
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0677
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8695
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55364
dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.07698
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90673
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03284
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958212
establishment of localization	GO Biological Process Annotations 2015	1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36832
SNB19	CCLE Cell Line Gene CNV Profiles	1.0	1.87692
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8543
8820_TERF2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.776517
SPI1	ENCODE Transcription Factor Targets	1.0	null
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54781
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8245
7943_SKIV2L_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.678114
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2448
hsa-miR-214	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82626
HDAC2	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16355
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051415
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998895
GTEX-O5YV-0526-SM-2I5GE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03593
PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30014
Perturb_15655_KD_Phgdh_SRP303616	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9248
Perturb_13289_OE_Axin1_SRP070058	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31031
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15657
GSE131649_2_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19667
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0659
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41184
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879424
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22068
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05234
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CREB1_01_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.29407
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04059
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dementia	GWASdb SNP-Disease Associations	1.0	1.06179
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17426
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC15	CCLE Cell Line Gene CNV Profiles	1.0	1.33386
GSE64642_0_v_1_sirt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46944
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64051
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87887
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.997181
SRSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14719
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04237
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11166884-mmc4.xlsx-Table_S3-Table_S3_proinflammatory-EC2_comparison_between_WT_and_TG_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04244
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.968681
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1753_KO_Stag2_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.23368
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2BPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60092
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30805
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75915
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03818
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I9-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69719
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4344-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07443
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21635
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07666
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2155
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24974
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25402
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84686
abnormal craniofacial bone morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915166
WM3772F	DepMap CRISPR Gene Dependency	1.0	2.3668
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3028
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1056
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07828
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46287
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3333
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874144
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.34711
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940824
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02817
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.89808
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16018
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24863
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25121
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.55927
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7026
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45003
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3607
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910558
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51712
Entorhinal area, medial part, dorsal zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30528
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956241
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78068
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.887208
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838921
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34409
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36512
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56236
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44266
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864216
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950727
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	2.12646
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
exocyst localization	GO Biological Process Annotations 2015	1.0	null
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63431
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.926207
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.21646
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03658
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049382
NKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27651
SNX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20234
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29617
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73253
Perturb_10708_KO_lncRNA Airn_SRP319190	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.72886
691_ATP8B2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.530613
supramarginal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24989
K562_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180406
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10211
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46632
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.9774
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48782
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.4902
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11536
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.44466
Perturb_12030_KD_ADORA1_SRP215261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874279
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68061
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844268
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68222
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57141
abnormal cranium morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal cranium morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99874
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03038
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16893
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
4593_LIN52_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.51219
inhibits	GeneRIF Biological Term Annotations	1.0	null
K562_PFI-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176593
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3584_KO_RUNX1_SRP312248	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.8863
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19657
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933764
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91563
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1754_KO_Stag2/Runx1_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39229
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872207
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
Lung adenocarcinoma_LUAD_TCGA-97-8179-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15011_KO_Eed/Xist_SRP365240	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.90036
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966301
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67974
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883443
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051709
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3299
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7645
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.32835
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.988957
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43784
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69648
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1339	CCLE Cell Line Gene CNV Profiles	1.0	1.34687
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56851
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10536
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31991
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05694
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76421
Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	1.59475
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE255680_2_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03732
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54781
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12261
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.925425
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48735
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08806
alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0816
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891699
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2468
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2394
CLPP_KO_GSE40207_380_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8087
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048533
SNU886	CCLE Cell Line Gene CNV Profiles	1.0	1.33008
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.83691
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13841
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56
Perturb_11979_KD_Etv5_SRP304972	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.5486
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03067
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GSE172494_2_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.678
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5695-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPLC272H	CCLE Cell Line Gene Expression Profiles	1.0	2.05295
U178	CCLE Cell Line Gene Expression Profiles	-1.0	-2.91428
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.52983
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38154
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QM-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
K562_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0235515
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2864
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.23555
4956_MED6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.612743
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33828
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30406
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75759
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923454
HCC44	CCLE Cell Line Gene Expression Profiles	1.0	1.40853
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42354
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04186
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78312
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6539
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.953
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72991
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49978
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6077
K562_Lenalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0227399
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27995
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12083
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043298
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL30	DepMap CRISPR Gene Dependency	1.0	5.08578
DOC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65923
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966316
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.54
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891228
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936383
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.8496
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12147
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93395
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17352
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.27602
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0442
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Kidney renal clear cell carcinoma_KIRC_TCGA-3Z-A93Z-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03092
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00469
Perturb_5818_KO_Gata2_SRP239807	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.04392
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19506
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878412
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.372
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_4_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17352
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828333
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71858
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15028
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.230982
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08693
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25679
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
secretion by cell	GO Biological Process Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6985
K562_Enzastaurin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151272
hsa-miR-193a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01212
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.34998
1351_CCT7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.807499
Ebolavirus(EBOV)_6day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.29518
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55744
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24434
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.18929
K562_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165903
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03407
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.839774
K562_Triamcinolone Acetonide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144959
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51219
GSE159084_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
4147_INTS2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.509422
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895589
Platelet count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.1699
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.44919
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30258
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49444
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2116
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34205
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.19139
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9226_TRAF2_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.591953
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72669
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44869
herniated liver	MGI Mouse Phenotype Associations 2023	1.0	null
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873108
PMC12081695-41598_2025_1907_MOESM1_ESM.pdf-17-MTERFD3_MTERF2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969828
Perturb_14133_KO|OE_Dnmt3a/Dnmt3b|Kdm4b|Kdm5b_SRP151021	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.13682
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902919
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.866321
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1182	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67862
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24321
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898786
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03693
2501_EFR3A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.502062
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZFC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77217
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28999
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10473
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31622
K562_Dacinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126076
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3444
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01483
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855469
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01445
abnormal tooth morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.111
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.08387
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27016
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10013
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.344
Perturb_1702_KI_HMGA2_SRP128920	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.10353
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36184
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS2_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	0.943481
HSMM	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.85042
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73615
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13083
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68724
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03772
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22936
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5307
increased circulating serum albumin level	IMPC Knockout Mouse Phenotypes	1.0	null
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61471
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16863
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18492
PSMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06064
Red blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45749
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13135
K562_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188276
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
PSMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44051
OVMIU	DepMap CRISPR Gene Dependency	1.0	12.5986
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927193
GSE184133,GSE184137_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16883
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12819
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4758-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11321
KU812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16964
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2715-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7079
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_4505_KO_Klf5_SRP374413	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.35482
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903587
GSE201309_1_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE110178_4_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64818
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64996
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00769
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888231
Perturb_17590_OE_Ppard_SRP230295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.12007
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31275
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17903
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.930188
FADS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18697
snare binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2157
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0949
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63023
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833039
population	GeneRIF Biological Term Annotations	1.0	null
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97123
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96475
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64394
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.242
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10787
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04916
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883531
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11714
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56234
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929519
t59-kidney_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.17455
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14782
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31947
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85169
Bladder-vein endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0749297
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.35508
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	3.87073
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940647
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06274
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041108
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A3Y1-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18364
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	2.00346
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61085
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052545
Body mass index (age>50)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.10458
suggests	GeneRIF Biological Term Annotations	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38394
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43334
SPI1	ChEA Transcription Factor Targets	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99977
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
No annotation - 2	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8726
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03909
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42354
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Avagacestat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180879
abnormal snout morphology	MGI Mouse Phenotype Associations 2023	1.0	null
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05362
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042011
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02986
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
NCIH1975	DepMap CRISPR Gene Dependency	1.0	2.37773
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27736
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85401
Perturb_16605_KO_Bend2_SRP357909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.23125
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7598
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22778
Meckel-Gruber Syndrome	DisGeNET Gene-Disease Associations	1.0	null
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28717
Necrosis	CTD Gene-Disease Associations	1.0	1.06844
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10245
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07974
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05449
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48556
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6797_PRPF3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.533821
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993569
Actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08497
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851337
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38774
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76779
4540_LDB1_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.70655
GSE237040_6_v_3_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
K562_PHA-680632_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213371
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1767
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75209
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10028
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836248
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12501
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.971655
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24587
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7389-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24052
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50989
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04716
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882181
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08226
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07304
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01001
USF2	ENCODE Transcription Factor Targets	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16714
K562_Crizotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148932
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41456
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20311
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNCA_KO_GDS4153_445_mouse_Striatum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02012
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00525
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12559
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.71533
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6817
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TC205	DepMap CRISPR Gene Dependency	1.0	6.35788
Lung adenocarcinoma_LUAD_TCGA-05-4417-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MSMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03169
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879343
GSE183251_7_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24184
Perturb_4616_KD_Rfx1_SRP231452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.90646
K562_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160058
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986523
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cofilin-actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29545
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04005
skeleton phenotype	MPO Gene-Phenotype Associations	1.0	null
Echogenic Kidneys	DisGeNET Gene-Phenotype Associations	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55273
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01337
SNU601	DepMap CRISPR Gene Dependency	1.0	2.85779
TCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62005
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41886
CEBPZOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45379
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838176
K562_Belinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180007
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.94045
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63325
1141_CAAP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.620251
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29285
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.84317
exocyst	GO Cellular Component Annotations 2015	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1759
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12759
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923274
abnormal mouth morphology	MPO Gene-Phenotype Associations	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50207
GSE223008_0_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1111
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-1526-SM-48TCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996061
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10809641-DataSheet3.pdf-119-ETV5_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01307
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91643
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64744
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33651
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895132
Arsenic	CTD Gene-Chemical Interactions	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885123
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04626
ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226641
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847913
Perturb_5243_KO_E2A_SRP272063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10581
GTEX-PWCY-1926-SM-3NB25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870477
near	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27314
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858083
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944872
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9194
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18728
single-organism process	GO Biological Process Annotations 2015	1.0	null
KNS62	CCLE Cell Line Gene Expression Profiles	1.0	1.60688
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966452
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.09498
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17352
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33106
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.43937
NFE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38542
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24124
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882058
hsa-miR-761	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30181
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.99504
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93589
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40892
PRELID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48748
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0965
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883604
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
Hydrocephalus	DisGeNET Gene-Disease Associations	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12572
Neurofibrillary tangle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944658
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44921
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7665
POT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10205
Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Tacedinaline_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150916
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1744
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05563
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.30473
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28301
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966966
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
K562_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146651
rectum	HPA Tissue Protein Expression Profiles	1.0	0.834979
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2381
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96697
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18294
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
impaired glucose tolerance	IMPC Knockout Mouse Phenotypes	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.922132
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23747
Perturb_17233_KD_KLF2_SRP389914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.53553
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47381
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861346
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.955623
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828358
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0317
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63W-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19631
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40395
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79153
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42463
K562_Mercaptopurine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152574
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62993
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04452
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952319
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
8218_SNRNP27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.659741
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1826
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16327
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11396
abnormal facial morphology	MPO Gene-Phenotype Associations	1.0	null
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33135
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.62107
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46675
Mean platelet volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09483
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61111
K562_MK-5108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182554
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1773
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.77421
r6 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12963
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894184
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0701
3986_HSPE1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.624867
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perturb_5584_KO_RELA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.9136
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5965
5768_NPLOC4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.55113
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5047
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39576
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957499
GSE232631_0_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCIMOH1	DepMap CRISPR Gene Dependency	1.0	5.68418
cellular protein complex localization	GO Biological Process Annotations 2015	1.0	null
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02416
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11845
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.29348
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.388
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-11A-12R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.4887
Lung-bronchial vessel endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.00867607
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal ductus venosus valve topology	MGI Mouse Phenotype Associations 2023	1.0	null
Exudative Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07666
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35636
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5936-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38963
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45963
Medial temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
SCABER	CCLE Cell Line Gene Expression Profiles	1.0	1.66405
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185891
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33242
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42813
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.0182
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853651
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24052
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5135
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24759
DENND4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07081
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11308
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89894
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979811
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47068
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903575
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08116
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839717
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68032
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular protein localization	GO Biological Process Annotations 2015	1.0	null
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0522
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838176
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05498
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	2.20996
E2F6	ENCODE Transcription Factor Targets	1.0	null
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051584
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1028
18955564-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
DACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39373
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82456
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60943
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16482
8196_SMYD4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.820267
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18268
Renal Cell Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.11775
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255234
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.834979
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.711
K562_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152855
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69689
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38769
K562_Cerdulatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0254819
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.3118
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10244
Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK2_knockdown_146_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.18029
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87492
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57338
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61995
SARS-CoV_24Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45113
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOP62	DepMap CRISPR Gene Dependency	1.0	8.52762
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44295
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29008
craniofacial phenotype	MPO Gene-Phenotype Associations	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.682
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20279
C75	DepMap CRISPR Gene Dependency	1.0	3.99521
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03918
GSE152432_3_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056843
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43493
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0502
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-1.22222
K562_Clevudine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227664
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23629
PMC3348545-NIHMS263168-supplement-3.pdf-390-ZNF45_ZNF45	Rummagene Transcription Factor Associations 2026	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06996
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74735
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040938
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1916
protein localization	GO Biological Process Annotations 2015	1.0	null
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49946
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25799
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27594
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05683
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966104
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.834979
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POU5F1	ChEA Transcription Factor Targets	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87757
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6823-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.30604
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954026
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
silencing	GeneRIF Biological Term Annotations	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40739
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16258
GSE184133,GSE184137_1_v_9_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0386128
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3211
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
phosphorylation	GeneRIF Biological Term Annotations	1.0	null
K562_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210895
BRPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86667
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02533
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07437
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30291
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37463
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98695
hsa-miR-431	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33323
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.967592
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850586
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4956_MED6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.54069
CLCN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01025
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11273
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99874
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882819
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25607
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13364
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05731
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28298
16498405-TableS3	GeneSigDB Published Gene Signatures	1.0	null
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	2.39358
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00769
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.1642
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
abnormal axial skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23693
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04916
GSE180951_6_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	0.834979
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45458
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05416
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98496
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14684
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52063
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.834979
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16496
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12154
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93278
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83605
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20848
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10607_KO_Kcnj8_SRP132855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.6655
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86693
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NJ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.13381
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58627
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08338
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.942944
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.14491
quantitative traits	GAD Gene-Disease Associations	1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13303
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72126
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00669
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.288993
CMK	CCLE Cell Line Gene Expression Profiles	1.0	1.44984
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	87.3227
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76032
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32748
joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.612958
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39368
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02003
H3K36me3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869164
CEBPZ_02_118	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.83007
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2975
GTEX-REY6-1726-SM-48FDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908981
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12538
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
6098_PAXBP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.532982
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66838
CAOV4	DepMap CRISPR Gene Dependency	1.0	2.06547
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949751
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56932
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Geographic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947481
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05731
SNU886	DepMap CRISPR Gene Dependency	1.0	7.05499
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38867
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16557
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2723
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08298
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4993-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.05644
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8519
GSE199874_3_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12182
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40395
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77813
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15651
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147662_3_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, barrel field, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0469
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHP212	DepMap CRISPR Gene Dependency	1.0	2.40403
hsa-miR-922	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61679
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59898
spleen	HPA Tissue Gene Expression Profiles	1.0	1.29375
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07784
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20472
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
secretion	GO Biological Process Annotations 2015	1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12868
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
10029_ZC3H8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.00882
DOV13	DepMap CRISPR Gene Dependency	1.0	3.10747
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	1.36111
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5645
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25812
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74503
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13084
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM236B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47945
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5687
UT7	CCLE Cell Line Gene Expression Profiles	1.0	3.39792
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03135
BICR6	CCLE Cell Line Gene Expression Profiles	1.0	1.81933
biological_process	GO Biological Process Annotations 2015	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05265
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11381
Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85726
K562_YM155_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135558
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09287
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248501_1_v_0_mst1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48627
K562_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0256422
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.28717
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02729
H4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53245
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00853
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57413
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
spleen_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.872011
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03232
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75901
K562_Tanespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164282
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49911
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.140636
GCIY	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919345
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53398
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
G292CLONEA141B1	DepMap CRISPR Gene Dependency	1.0	2.56362
salivary gland	HPA Tissue Protein Expression Profiles	-1.0	-1.22222
4147_INTS2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.61248
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47542
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96062
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
K562_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144043
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22488
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95543
PPME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12144
CITED2_02_38	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62449
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64223
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09024
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.48594
Kidney-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.208699
A375SKINCJ2	DepMap CRISPR Gene Dependency	1.0	5.37323
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38215
PIGU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47659
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7564
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0201
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54349
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23026
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00769
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39772
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.4902
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11328671-jitc-12-4-s003.pdf-101-ETV3L_ETV3L	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRL_Deficiency_GDS1693_239_mouse_Photoreceptors cells of retinas at 4 weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913231
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44921
Prostate-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.735415
MKS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.466
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95241
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48395
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2492
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54617
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00413
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	3.03714
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3039
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53452
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4733-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0088
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03228
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5922
decreased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838176
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19936
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.411631
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.37126
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840783
GSE67266_7_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88743
GTEX-UPK5-2126-SM-4JBJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836659
K562_Tazemetostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177816
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55272
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neutrophil Count (Procedure)	DisGeNET Gene-Phenotype Associations	1.0	null
cellular macromolecule localization	GO Biological Process Annotations 2015	1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28865
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69I-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5856
PACADD161	DepMap CRISPR Gene Dependency	1.0	2.46318
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48061
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Z-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13457
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12022
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.337608
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2989
GLDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52456
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49657
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.082158
TNFRSF10D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92389
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33767
stomach	HPA Tissue Protein Expression Profiles	1.0	0.834979
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05433
GSE87299_2_v_3_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38187
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68585
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1504
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06983
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.38848
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42673
GH4-C1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965992
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20438
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.408309
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01421
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal cranium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE202434,GSE202438_12_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28575
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57901