association	dataset	threshold value	standardized value
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84429
Adrenocortical carcinoma_ACC_TCGA-OU-A5PI-01A-12R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K27406233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33696
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71267
eosinophilia	GWASdb SNP-Disease Associations	1.0	0.679961
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07823
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58615
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79090631_CGP-60474_HS578T_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-1.0017
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18161
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES8	DepMap CRISPR Gene Dependency	1.0	9.34391
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.982144
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50864
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBASH3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582142
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR0B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00647436
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25905181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15172
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16856
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04853698_-666_SW620_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04108
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IPO13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41605
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22702
GTEX-X5EB-1426-SM-46MVW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06719
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Nephroblastoma_Renal Tissue_GSE2712	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.53494
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20197
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.25746
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830632
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77097
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36853
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149075_3_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAAP24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669814
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958387
Perturb_3741_KO_Gna13_ERP130529	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.7262
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851522
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04563
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ABL1_knockdown_137_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.73257
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905251
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45105
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1928
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.4148
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43166
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75141
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.194334
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18705
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17239874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50182
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.371
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
natamycin-3548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K59484021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28704
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCB-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3421
BRD-K76539747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38646
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
NUSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53984
TOMM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05361
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2-PMDQ	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53087
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26596
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14183
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30428
CDK7_knockdown_138_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.99375
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77697841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12281
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A64374397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59225
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38527
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trichostatin A-3566	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_9831_KO_SIX6_SRP256351	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12420540-44154_2025_254_MOESM1_ESM.xlsx-supplementary_S7-FST_PI_XPCLR_TGB_VS_ZSG_gene_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K78500251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23274
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Postaxial acrofacial dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38239
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4383
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936807
BRD-K98465548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16181
VSIG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509283
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27645
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.03419
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100644_HIP_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00773
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94239
BRD-K97013733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12131
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27276
HADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25965
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0426
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41266
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14784
BRD-K08629159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7665
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74567
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3799
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979982
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18332967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09617
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dh15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.608
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62378
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.931
BRD-K66551929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00639
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7171-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2778
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78643409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02473
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04055
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.907004
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.50574
Inflammation	CTD Gene-Disease Associations	1.0	1.55995
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.46067
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.38513
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882026
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01061
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15429
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877125
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76093
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26153
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47323
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.040944
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
m1Lim (VL) part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25483
oxytetracycline-3170	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4503
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VMRCRCZ	CCLE Cell Line Gene Expression Profiles	1.0	1.50293
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08138
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10411
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826639
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.64917
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05936
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01585
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10532
GTEX-T5JC-1826-SM-4DM6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13982
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1508
BRD-K06332513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31876
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04188
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.10769
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE105170,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4680-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09249
BRD-K52340217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51639
BRD-K47170544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16648
saquinavir-6127	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ABCD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559034
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.56222
Lung squamous cell carcinoma_LUSC_TCGA-56-8625-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862821
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945139
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1227
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49247
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18409585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73845
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13436
HCC1599	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.83684
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879271
BRD-A86977540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81426
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920635
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43858
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.84167
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.37759
PPP4R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00532906
BRD-K62909976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02483
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2621
icSARS CoV_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.87262
BRD-A15086915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72514
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.19937
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22417
CEP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15468
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98969
NR2F6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00502816
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	0.858251
GTEX-OIZG-0926-SM-3LK5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9841
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC97TM1	CCLE Cell Line Gene CNV Profiles	1.0	1.34205
BRD-K32380923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19419
PRDX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657063
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32158
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923276
Perturb_18483_KO_Ptk7_SRP106722	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.8127
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35765
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44261
BRD-K17209411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44288
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86341
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13197
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869935
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXD9_HOXD9	Rummagene Transcription Factor Associations 2026	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A69786436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11268
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A115-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE117045_1_v_0_amphetamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
697	CCLE Cell Line Gene CNV Profiles	1.0	1.85623
RGS10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00654363
Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114258_3_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23598860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08549
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34077
BRD-K26024910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10195
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31063
BRD-K97624648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11475
IMR-90 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
EDA2R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00426085
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38445
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911103
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.050002
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4643	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
A704	CCLE Cell Line Gene Expression Profiles	1.0	3.40798
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908235
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.371
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15322
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02057
Hypertrophy	CTD Gene-Disease Associations	1.0	1.2336
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831919
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73839552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33565
SERPINB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00563749
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20863
FCSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1185
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-764	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CRCGN017_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03395
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.32603
famotidine-6665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.03493
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966362
BRD-K74095559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.153
BRD-K12343830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64491
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.32251
BRD-K66016089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37596
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23484
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.5191
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ALMS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621448
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914279
BRD-A96007399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07846
DANG	CCLE Cell Line Gene CNV Profiles	-1.0	-2.51079
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amyotrophic lateral sclerosis	GWASdb SNP-Disease Associations	1.0	1.00407
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20922
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.77
GSTA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051865
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0952
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0911
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_10_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAVIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69067
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NH12	DepMap CRISPR Gene Dependency	1.0	2.45948
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.19937
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53721
ZNF219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30151
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34845
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.056307
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15485
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15137
BRD-K79090631_CGP-60474_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03889
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16135
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17473
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.969147
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.5017
BRD-K13662825_dinaciclib_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dimethadione-4607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5087
GSE190316,GSE190324_0_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00662752
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07756
Fetal Death	CTD Gene-Disease Associations	1.0	1.6621
BRD-K27680690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49309
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7551
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.29348
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21331
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65177
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94341
GSE195559_8_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7825356-8844261.f3.docx-53-SPEN_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
TREX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582466
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37513
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30407
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K43909206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31213
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52463
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62189
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.02512
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13251
GSE109285_3_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02168
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13251
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.824083
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15508
BRD-K32718856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16899
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6937
BRD-K60952519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07929
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1667
BRD-K13662825_dinaciclib_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15898103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04274
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9174176-41467_2022_30924_MOESM5_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78266
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dactinomycin_mus musculus_gpl1261_wild type_gds2456	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
BL-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.56996
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20222
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_18_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Cholestasis	CTD Gene-Disease Associations	1.0	1.13041
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.32741
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.39232
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17326
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04606
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30938
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17474512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42669
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17815
hsa-miR-4691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PMC9576445-IJG2022-9264555.nxml--Potential_targets_of_hsa-miR-16-5p_AND_hsa-miR-184_NOT_hsa-miR-15b-5p_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SL-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF_01_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59337
tolnaftate-4221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	0.909921
GSE203655_0_v_1_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE188721_3_v_1_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902181
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873905
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	11.6996
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.19937
motor neuron disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
SIRT4_KO_GDS4823_30_mouse_hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27872
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29001
SATB2-associated syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.074
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A89846380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46452
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929982
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86285108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62001
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874794
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3120-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.946654
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN008_HEPG2_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05868
egr1_20019881_retina_lof_mouse_gpl1261_gds3607	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.211612
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03447
BRD-K60799989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0474
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19376
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33473
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2353
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59843356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74888
GTEX-X638-0226-SM-47JZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16284
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.8786
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08607
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27404
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91186
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.27977
hsa-miR-3615	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
dihydroergotamine-6840	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4768-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
KLF5_KO_GDS3509_553_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50792
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89784
myocardial infarction	GWASdb SNP-Disease Associations	1.0	0.679961
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22842
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19819
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40871
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900699
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01628
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88604
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Raf-1_OE_GDS1925_166_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CDK2_knockdown_132_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.5154
Perturb_3907_KO_DUSP6_SRP229874	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.41298
KDM5A	ENCODE Transcription Factor Targets	1.0	null
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.72916
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
solanine-2152	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97485956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79377
GSE215086_0_v_2_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.4449
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.045946
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09038
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22483
ADORA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0050555
Perturb_16775_KO_Utx/Jmjd3_SRP339500	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.45087
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.10536
BRD-K48699175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06039
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09819
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.3076
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899483
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDKN2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00757679
GOLGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12307
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00208
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02732
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967217
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4799
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48851
RO82-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K53354260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07281
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61455
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09191014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55603
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103372_1_v_2_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28211
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09199
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03248
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37137
DOHH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059334
NEIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17842
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parkinson's disease 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
BRD-K75724196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71753
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51966
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.45199
vincamine-2367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16689
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
levallorphan-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82343
chr4_186191887_C_G_b38	GTEx eQTL 2025	1.0	2.96709
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2395
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.14576
tcf12_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.050947
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78929
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A92729194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62255
OUMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60695
cancer	GWASdb SNP-Disease Associations	1.0	0.042207
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMARCA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00438033
chr4_186107501_C_G_b38	GTEx eQTL 2025	1.0	2.21334
periventricular stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14142
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diltiazem-6710	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16266179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00599
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23026
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05149
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79222491_2-morpholino-9-(thiophen-3-yl)-N-((5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)methyl)-9H-purin-6-amine_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900996
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RSC1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549033
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68218
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10953
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978109
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-0626-SM-4KL1S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78714
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4569
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08668
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.76341
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15284_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.5873
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44701
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875354
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06593
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12549544-mmc2.xlsx-AA_D21_VS_D28-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
isthmic liminal part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15924
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05662
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-1.816
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74485
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2575
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18253
Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10176883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22754
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.35589
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE173873_2_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44768
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A94465834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1898
SLR21	CCLE Cell Line Gene Expression Profiles	1.0	2.53622
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11719
BRD-K41202439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18387
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68783
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2685
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62384
BRD-K40961223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23201
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.11011
BRD-K53612850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58571
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02027
BRD-K67141726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51601
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.73393
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03066
CHEK1_knockdown_136_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.46482
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.875706
BRD-K07614312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43067
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14670_KO_Lkb1_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.9826
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLXNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546056
TBC1D7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00602842
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NUAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553168
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974882
Epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EED	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627622
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.22246
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08607
CTU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16424
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79090631_CGP-60474_MCF7_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.31792
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56348
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
11751374-Figure3	GeneSigDB Published Gene Signatures	1.0	null
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902623
hsa-miR-627	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870435
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58841
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MARK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599635
alprostadil-4179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
spectinomycin-2987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73717
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01458
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945681
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
19061838-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00599
ERG	ChEA Transcription Factor Targets	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3455
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47617
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.42211
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09336
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Gastric	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.847811
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
myocardial infarction	GWASdb SNP-Phenotype Associations	1.0	0.582578
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39165
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KE37	CCLE Cell Line Gene CNV Profiles	1.0	1.59275
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-11A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33151
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21005
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04461
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06041
lower dorsal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11241
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
PL4	DepMap CRISPR Gene Dependency	1.0	8.74929
BRD-K87617154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05537
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62665
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21667
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20922
DKMG	DepMap CRISPR Gene Dependency	1.0	2.36823
sanguinarine-4168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.360769
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4102
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07487
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.332015
DNLZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01329
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25652
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.13911
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4957
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9931
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60529
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83189379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09625
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2095
COLO205	DepMap CRISPR Gene Dependency	1.0	8.49762
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52486
GSE173873_10_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9043
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.186
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.15763
Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217541,GSE217543_3_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875595
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09814
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80693
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00801
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12933
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23622
hsa-miR-4453	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
znf263_19887448_helas3_lof_human_gpl6884_gse19146	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.177007
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3645
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16631
BRD-K31960013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64989
Fatty Liver	CTD Gene-Disease Associations	1.0	1.78816
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K82102352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14638
PMC4060771-170289.f1.pdf-413-EBF1_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
KMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.63575
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08389
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2793
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44948
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.19937
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55086
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-1326-SM-48TYY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19973
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-11A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855787
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.31985
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MOGGUVW	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9682
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.040736
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34415
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21168
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.05265
BRD-K01888220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67737
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66386
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831558
pancreatic cancer	GWASdb SNP-Disease Associations	1.0	0.787916
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01848
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4767
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
KCNMB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495379
GSE138672_4_v_3_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2199
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-1226-SM-4DM7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850432
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3479
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15734_KO_Kmt2d_SRP058264	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99198
hsa-miR-512-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881959
hsa-miR-136	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957291
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63113
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4P3-0526-SM-4AD58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15612
hsa-miR-3161	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81681
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7713
Perturb_13715_KO_ASXL3_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.61193
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95004
MAZ	ENCODE Transcription Factor Targets	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.97434
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38322
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
16912175-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
BRD-K22748970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09143
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934541
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.62658
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-M39894156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49093
RMGI	CCLE Cell Line Gene Expression Profiles	1.0	1.675
GSE131161_5_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K13390322_AT-7519_LNCAP_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K35964249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47707
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20441
A-CA-04-2009(H1N1)_30Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.8977
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28149
LAPTM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00826698
BRD-A91823394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06265
BRD-K24205443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00985
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24855
IGROV1	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.02837
propoxycaine-3583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Corneal endothelial dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.06114
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16164
GTEX-RWSA-1326-SM-47JX9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65813
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36394
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.80643
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48017
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05379
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31298
Perturb_16965_KD_S100a4_SRP345370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77869482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23116
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27628
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.5986
BRD-K36718828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10365
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.84966
KINGS1	DepMap CRISPR Gene Dependency	1.0	5.44698
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43354
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829597
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8X3-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23895
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34819
gm02185	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.18
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74079
levocabastine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16646
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80349
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44833
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949617
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35041
abnormality of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.387806
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940257
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59183
MREG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513674
BRD-K32431589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34843
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5925
BRD-K26591929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15213
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.579
PMC10197848-12885_2023_10795_MOESM5_ESM.xlsx-Sheet1-ESR2_overexpressing_MCF7_cells_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EW7	DepMap CRISPR Gene Dependency	1.0	6.97432
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K18245187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55012
PMC8481886-Table_1.xlsx-A_subsets-adipose_tissue_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78838
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73258
PTPRC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575634
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10716
BRD-K59851511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05161
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TTC30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73419
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02579
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38494
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71448
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6691-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49896
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14195
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19326
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06282
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.73454
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48226
TCF4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996942
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37291
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
isometheptene-3145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16502264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06376
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00516
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32648
HCC2218	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Portio vaginalis cervicis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25023
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56719
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927016
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08857
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.15609
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14606
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14782
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64898
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.101081
BRD-A59985574_T542500_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94452277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35257
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23165
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902181
BRD-K23432132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.035
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45112
MPP-89	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2418
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4639-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RCC10RGB	CCLE Cell Line Gene Expression Profiles	1.0	1.94449
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
hsa-miR-376c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41676
CDK8_knockdown_147_GSE32108	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.71655
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991073
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02232
BRD-K01676126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11568
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.28119
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17952
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20112
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03325
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_12_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77101974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1294
BRD-K79090631_CGP-60474_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A82843133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71914
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16802
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14349
GSE228125_0_v_3_ptafr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.83137
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13582
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955575
RERG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00709485
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.904085
Facioscapulohumeral muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.208
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3587
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34764
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE229102_1_v_0_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LIVF001-015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.364
Kidney Chromophobe_KICH_TCGA-KN-8426-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07455
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31015
brain	GTEx Tissue Gene Expression Profiles	1.0	0.879823
ZM-226600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16159
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827584
BRD-K35133923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.019
Facioscapulohumeral muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
BRD-K68970089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34596
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
fisetin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09485
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K87909389_alvocidib_HS578T_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACVRL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00544087
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-GSEA_siYAPsiTAZ-SITAZ_UP__MYC_EZH2_H3K27M3BOUND_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-GSEA_siYAPsiTAZ-si_YAPUP__MYC_EZH2_H3K27M3BOUND_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4101
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.198976
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90658
RP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00532472
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47948
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33468
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.55666
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944501
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64432
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4153-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32288
GTEX-WH7G-1026-SM-4LVML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01147
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00262
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01845
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886412
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU72-0826-SM-46MUS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07945
BRD-A14183911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72574
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3667
NB69	DepMap CRISPR Gene Dependency	1.0	2.84583
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
M059K	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71418
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.955577
BRD-K19325444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28565
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3372
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01826
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91738
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.910423
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4814-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17938
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	3.39931
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09249
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.85766
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22571
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZACN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579925
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28888
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3502
BRD-K06666320_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891096
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00145
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU1272	CCLE Cell Line Gene Expression Profiles	1.0	2.04416
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34457
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72191
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13966
BRD-K53293966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96727
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01495
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887774
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.14671
GSE153189_1_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938279
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0786
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MMACHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064162
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.21951
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CD93	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566063
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226249_5_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VN(H5N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.14697
FFAR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563303
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03521
LMBR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00645174
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17239
CDK8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00437883
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K13662825_dinaciclib_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59092
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02324
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00252
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cervical mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU478	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92819
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11523
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49567
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957744
LHX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00731171
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35685
TUHR4TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.85348
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949239
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.088697
GSE182680,GSE182683_5_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K05357297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17377
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19027
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36605
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45901
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6429
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
KCNH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568152
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11054
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44205
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87415
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11643336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28411
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GSE156667_0_v_1_lrrc8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
20081105-ST-1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K21680192_mitoxantrone_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29182
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4223
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26243
Necrosis	CTD Gene-Disease Associations	1.0	1.78302
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838018
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852746
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr4_186191475_G_C_b38	GTEx eQTL 2025	1.0	1.2813
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01122
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19211
TCEANC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4585
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19108
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EI-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lung disease	GWASdb SNP-Disease Associations	1.0	0.219075
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03551
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4519	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Lung adenocarcinoma_LUAD_TCGA-55-7914-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37073
hsa-miR-152	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7764-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0215
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40048
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19069
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53821
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15137
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.909252
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29169
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.151422
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827584
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991439
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00801
GATA2	ChEA Transcription Factor Targets	1.0	null
BRD-K33044659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05319
ITGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53561
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44992
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT1_knockdown_135_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29275
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38768
BRD-K98529522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40493
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09519
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZR-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85722200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61484
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09004
AM-095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50041
Peters plus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.100179
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03952
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27402
BRD-K06058625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41737
Regio oralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92605
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.661158
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.833997
Perturb_15307_Mut|KD_Kras_SRP360531	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46312
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5102-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877658
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31282
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967984
BRD-K18944654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35615
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40727
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12247
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TX-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66318
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25153
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10138
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96978
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52175
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6427
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8119
periventricular stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0238
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43708
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR1-List_of_differentially_expressed_genes_in_AR11_vs_AR1_Negative_value_means_down-regulation_in_AR11_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A2C7-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13390322_AT-7519_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE165689_0_v_1_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HUP-T4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN014_HEPG2_3H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23139
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23911
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INTS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681994
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.645
EHMT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549726
Sarcoma_SARC_TCGA-UE-A6QT-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAIR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676616
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6088
BRD-K41690760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76586
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2793
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40944
BRD-K49630774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23668
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3768
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14833
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24132293_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45129
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27353
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24083
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2774
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.648
NB17	DepMap CRISPR Gene Dependency	1.0	2.36424
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52456
GSE166004_3_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
APLN_KO_GDS3228_601_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A894-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21680192_mitoxantrone_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824507
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880427
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35211
GTEX-P78B-0226-SM-3NB1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878225
GLDC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00493068
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63241
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07274
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80916
hsa-miR-4522	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10458
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03075
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20094
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866643
HDAC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00327871
BRD-K77820762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57903
GTEX-XQ3S-1026-SM-4BOPJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05361
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910787
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
18081427-TableS8	GeneSigDB Published Gene Signatures	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22997
PAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31427
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18104
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-11A-12R-A26B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ZDHHC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1614
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941257
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06258
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K20377072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08088
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05677
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05544
SCLC21H	CCLE Cell Line Gene Expression Profiles	1.0	1.55422
CARD11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563378
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02621
Perturb_3410_KD_Zbtb10_ERP123680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.7447
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8966
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPINK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00545112
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35103
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876278
PKD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00666718
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.231965
RUNX1	ChEA Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07265
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5461_KO_Flvcr2_SRP192638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.8618
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.116394
BRD-K13662825_dinaciclib_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.5885
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I2-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77903467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08457
Oligospermia	CTD Gene-Disease Associations	1.0	1.14713
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MB21D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65918
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7709
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03519
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58776
Muscular Diseases	CTD Gene-Disease Associations	1.0	1.03419
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148658_1_v_0_six6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perturb_14107_KO_Setd2_SRP220107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.2716
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27538
BRD-K60437668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59759
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30731
HEC1A	CCLE Cell Line Gene Expression Profiles	1.0	1.47403
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871799
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.8974
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53352
GLIS3_KO_GDS3812_500_mouse_Embryonic pancreas at E15.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-OOBK-2025-SM-3LK5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866083
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32983
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65807
BRD-A81615860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21737
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911821
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20138
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86513
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A85216385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49119
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2778
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.501448
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A04618830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30294
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
BRD-K02073410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1753
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subiculum, ventral part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01233
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0053
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992724
PEER	CCLE Cell Line Gene CNV Profiles	1.0	1.54592
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.02634
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15286_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.11891
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.029562
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16086
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934452
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47544
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51639
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47482563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79304
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBR2_KO_GDS5008_282_mouse_Embryonic palatal mesenchymal cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.293281
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51J-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKRC31	CCLE Cell Line Gene Expression Profiles	1.0	1.91264
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26654
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64437
BRD-K57724551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16074
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12536
BRD-K21680192_mitoxantrone_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZH-1126-SM-4DXUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42019
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.39797
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.431531
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14566
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.993103
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85043
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19985
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28249
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8986
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21783
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78929
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03963
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.26904
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
GANAB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057347
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86097
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08541
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Palatine uvula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
ADRA1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642264
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28213
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20472
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-11A-12R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bacampicillin-4592	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8073-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99545815_PF-562271_HS578T_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ANKRD44	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555446
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ATTENUATED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904242
motor neuron disease	GWASdb SNP-Disease Associations	1.0	1.00407
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05344
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8326
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02296
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Leukemia, Chronic T-Cell_T lymphocyte_GSE5788	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.77875
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994907
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.955965
Perturb_9615_KO_Mll1_SRP255888	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.1243
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15457
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938675
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936511
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4975-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63068307_ZSTK-474_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LP1	CCLE Cell Line Gene Expression Profiles	1.0	1.40718
(-)-MK-801-3081	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SARS-CoV MA15_Day2_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.7125
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Awn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.836576
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.58477
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49478
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37342
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70238
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940222
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63981
appendices_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.952055
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56578
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23957
KNG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00550371
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siTAZ_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07756
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0798
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00154
Lung adenocarcinoma_LUAD_TCGA-86-8056-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
hsa-miR-4426	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.903865
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_16958_KO_Drp1_SRP173900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.56837
Perturb_9379_KO_lincRNAEPS_SRP354143	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K55282910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12618
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.939808
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14729
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	1.43872
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.64895
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.6102
BRD-K97943226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48308
GSE244072_11_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88224221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20209
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43789
CHD1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02657
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888517
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52011
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.975893
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.396313
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68995
BRD-K06614664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08763
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10872
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.042834
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.4796
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
atrophy/degeneration affecting the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.882984
SRF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00434214
GTEX-R53T-1226-SM-48FCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946939
HLE	CCLE Cell Line Gene CNV Profiles	1.0	1.45426
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60762
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
Pancreatic Neoplasms	dbGAP Gene-Trait Associations	1.0	0.151659
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K14942405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28772
Protein of unknown function DUF3719	InterPro Predicted Protein Domain Annotations	1.0	null
disulfiram-2215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55755
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.54438
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4730	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869875
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917536
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-384	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13566078_BMS-345541_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	2.26713
hsa-miR-4326	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910234
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26418
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24654
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04548
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31954
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22918
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33093
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.06881
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00837
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.917558
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.044346
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05761
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4865
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04393
BRD-A95480808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39223
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PH-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
latamoxef-3028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867395
BRD-K82517280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08604
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62445
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05209
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3451
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02757
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.26981
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05946
chr4_186093824_G_A_b38	GTEx eQTL 2025	1.0	1.34017
eosinophils	GAD Gene-Disease Associations	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9346
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05738
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11254
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56564
BRD-K39390441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20541
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.19412
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79090631_CGP-60474_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19353
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.371
BRD-K96510191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38246
nucleus of Barrington	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22072
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54226
meptazinol-4188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K30236306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61368
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960345
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0186
riluzole-4689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27177
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4027
GSE244072_4_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40344
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT116	BioGPS Cell Line Gene Expression Profiles	1.0	0.886296
PMC4728380-ncomms10153-s8.xlsx-High_affinity_MYC_Targets-Unnamed_0_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27599
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982167
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25737
KE37	CCLE Cell Line Gene Expression Profiles	1.0	1.3891
TTI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23491
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85931
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881702
Brain Lower Grade Glioma_LGG_TCGA-DU-6403-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIMM13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047043
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	1.56569
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.672
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66454
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855666
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.30208
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KMRC3	CCLE Cell Line Gene Expression Profiles	1.0	2.48068
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K54233340_Dorsomorphin dihydrochloride_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K17675814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31662
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGALS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546073
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.36247
BRD-K57356416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26052
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5054
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.999229
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-148b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21851
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57889
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09778
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09656
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26344
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20094
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36799
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17365
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00251
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82339
BRD-K05616059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20005
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr4_186185716_G_A_b38	GTEx eQTL 2025	1.0	1.69447
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-924	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5525-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890735
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44777
Autoimmune thyroiditis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.371
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.21471
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.968337
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DGKZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03253
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.80808
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t60-adrenal_female_2w	MoTrPAC Rat Endurance Exercise Training	1.0	2.82299
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.487
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98258
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932095
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.226
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960345
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74572
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990952
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04161
Acute Myeloid Leukemia_LAML_TCGA-AB-2860-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07573
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-A60076435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08645
chr4_186108242_AGT_A_b38	GTEx eQTL 2025	1.0	1.25186
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41744
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865643
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.2239
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38955287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06515
Perturb_18495_KO_Ercc2_SRP286486	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29173
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26596
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07921
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZBTB40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05385
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0333
STAB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461854
BRD-K84054400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23963
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33999
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10117
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K23326916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0676
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00016
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31282
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH82	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57404
motor neuron atrophy	GWASdb SNP-Phenotype Associations	1.0	0.882984
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20922
dexibuprofen-6712	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.18059
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89320330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68149
BRD-K98224452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21716
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	1.84947
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SPDEF_01_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.35441
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17636
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37219
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4801
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K04067194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81868
endocrine gland cancer	GWASdb SNP-Disease Associations	1.0	0.387072
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8473
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00081
CAKI2	CCLE Cell Line Gene Expression Profiles	1.0	1.36939
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08463
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30837
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4708-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
R-atenolol-4259	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	1.74426
ZNF583	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06616
SPHK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00690105
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845112
SUZ12	ENCODE Transcription Factor Targets	1.0	null
BRD-K95943192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3154
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMWD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13402
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07756
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20501
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.09512
H2803	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14596
Lung adenocarcinoma_LUAD_TCGA-97-7547-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81418486_vorinostat_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
zuclopenthixol-4261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30252
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71374
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23744
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845224
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52475
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-1226-SM-4DXT6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04665
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68291
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14806
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.48582
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2395
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70315
GATA3	ENCODE Transcription Factor Targets	1.0	null
RENBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00674513
HLA-DMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484059
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.08231
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79604175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26917
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.910546
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ronidazole-6134	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2716-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
estradiol-6928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01208204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02915
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50571
IL36G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603585
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99034771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60922
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97479
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.67212
Uterine leiomyoma_Uterus_GSE2725	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.19541
BRD-K07061353_7909011_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K70543679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15459
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00615
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15891
A204	BioGPS Cell Line Gene Expression Profiles	1.0	1.05048
BRD-K02050740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70533
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97242998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49817
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3803
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.03752
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888607
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.896298
Perturb_146_KD_Mettl3_SRP033779	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.85282
HHV-8_72Hour_18587055_GSE6489	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.64411
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11217
Perturb_15777_KO_Nmnat1_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.96515
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01682
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95683
BRD-A27693633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12983
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13103
BRD-K72414522_AZD-5438_MCF7_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
BRD-A17120244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99069
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIMA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32818
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39406901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67423
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12756
GSE131161_3_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922253
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.22388
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
picrotoxinin-4260	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952578
BRD-K17065706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86199
abnormality of granulocytes	GWASdb SNP-Phenotype Associations	1.0	0.293281
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855775
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.36677
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.61942
PMC4728380-ncomms10153-s6.xlsx-Pre-ranked_gene_list_MYC_Target-Supplementary_Data_5_GSEA_analysis_of_c-MYC-bound_promoters_in_control_HFF_MYC-ER_cells_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Hennekam syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79090631_CGP-60474_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H647	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71414
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28511
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34342
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.862189
MFM-223	COSMIC Cell Line Gene Mutation Profiles	1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.081
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04247
SLC6A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00528284
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE190534,GSE190536_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65959331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47089
PMC4521181-oncsis201520x8.pdf-15-ARNT_ARNT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siYAP_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
HAO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00727658
Perturb_5706_KO_Abcc8_ERP119268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36698
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BAG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526796
BRD-K53046137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25012
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944469
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61082
BRD-K70712801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04067
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11399095-44161_2024_532_MOESM14_ESM.xlsx-Sheet1-Supplementary_Table_13_DEG_in_the_AA_borderzone_in_AF_vs_SR_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86466947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06746
BRD-A89575866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01721
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21003
BRD-K18620798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13276
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr4_186177889_G_A_b38	GTEx eQTL 2025	1.0	1.65674
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66979
BRD-K49371609_528116.cdx_MCF7_24.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.25919
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A91461229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4525
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	5.09507
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.47209
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.40677
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	7.67329
RIDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00545924
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.095858
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.31148
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.3652
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-KLF6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung Diseases	CTD Gene-Disease Associations	1.0	1.14747
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839135
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23619
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149075_1_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0626-SM-4DM6P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954737
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888652
Chromosome 22q11.2 microduplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.70467
BRD-K85996308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41111
BRD-K37000177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01307
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_01_162	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60438
CIC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561482
19088021-supptable2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TRPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518587
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988932
SW780	CCLE Cell Line Gene CNV Profiles	1.0	1.71023
BRD-K15943105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26135
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.19937
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36469
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CKMT1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00390486
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48321
GTEX-T2IS-0926-SM-4DM5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49406
Lung adenocarcinoma_LUAD_TCGA-93-7347-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48882
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amyotrophic lateral sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.882984
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.302
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27641
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947426
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75343
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A30369394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46169
MTMR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36997
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14502
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.053109
Hyperplasia	CTD Gene-Disease Associations	1.0	1.91084
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.851886
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-HOXD4-Unnamed_8_HOXD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31046
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.24056
NCIH810	CCLE Cell Line Gene Expression Profiles	1.0	1.57918
BRD-K71533707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30551
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07898
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44260904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27464
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21496
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73105
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39805
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25566
artery disease	GWASdb SNP-Disease Associations	1.0	0.110457
BRD-K05753543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78386
Skin Diseases	CTD Gene-Disease Associations	1.0	1.09083
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06528
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.061261
GTEX-TKQ2-0926-SM-4DXU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22767
BRD-K08409548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949394
BRD-K27347421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12579
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-1026-SM-48U16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19505
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.047214
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25733
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892219
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959166
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74300740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40093
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR7-List_of_differentially_expressed_genes_in_AR11_vs_AR7_Negative_value_means_down-regulation_in_AR11_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-1926-SM-4DM6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04055
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35197
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924462
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.24812
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.28832
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A93436351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16554
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5793
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.18
bephenium hydroxynaphthoate-3089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35188
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53727
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pancreatic neoplasms	GAD Gene-Disease Associations	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-U86922168_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM53C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1434
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.854004
BRD-K87909389_alvocidib_MCF7_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JJN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25848
BRD-K53417444_OTSSP167_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K72335238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32068
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857609
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51557
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-06A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.02856
PALS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511375
zardaverine-4209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28848179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62284
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976291
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GAMG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
chr4_186150667_T_C_b38	GTEx eQTL 2025	1.0	1.39862
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8321895-41375_2020_779_MOESM4_ESM.xlsx-marker_genes-TAL2_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03412
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80778
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894419
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.19345
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831558
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48688
LIVF001-002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75836
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57652
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06805
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28436
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1353
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87745
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10204
BRD-K43389698_BMS-387032_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.924599
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47589
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.048946
AR	ChEA Transcription Factor Targets	1.0	null
GTEX-R53T-1026-SM-48FCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08477
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28222
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946488
Rett Syndrome_frontal cortex_GSE6955	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.96549
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DHX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39726
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.83576
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26727
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74015591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33887
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PIK3CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0065138
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22571
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	2.11143
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66117
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.535
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K28349636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04726
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
chr4_186171864_G_T_b38	GTEx eQTL 2025	1.0	1.14958
Ablepharon-Macrostomia Syndrome	DisGeNET Gene-Disease Associations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SRF_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.219075
hsa-miR-4647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56476
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
neoplasm of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.684849
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.96518
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978874
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14031
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04576
Edema	CTD Gene-Disease Associations	1.0	1.14781
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K49401787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15085
BRD-K14719962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41179
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44291
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07269
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929147
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27731
LB2518-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36237864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58361
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33431
GSE100316_5_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.293281
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79090631_CGP-60474_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875881
Lung adenocarcinoma_LUAD_TCGA-67-4679-01B-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03385
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21761
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00162
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05924
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04955
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5823
vascular disease	GWASdb SNP-Disease Associations	1.0	0.079171
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23215
hsa-miR-342-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07279
Liver Diseases	CTD Gene-Disease Associations	1.0	1.27533
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24822
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.38102
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38366
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90176
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_1451_KO_Akirin2_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.54356
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.038
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30021
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40248932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2641
BRD-K55479099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08181
CENPU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544565
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05892
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873246
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43914
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60566
central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00094
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993414
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72152
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K56332068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18873
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DOHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897819
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	1.15294
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.372451
BRD-K69158240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0436
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95151
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.146444
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902181
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBEW-1426-SM-4AT4J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921044
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.36303
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35201
Perturb_1556_KO_Srpr_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.35599
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pf382	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K97798118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33468
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GSE154767_2_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gemcitabine_homo sapiens_gpl96_gse6914	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K37219127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20492
BRD-A46566149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27411
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_01_120	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.78585
HEL	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05589
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36805
Sickle Cell Anemia_Endothelial cell_GSE9877	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.9224
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20094
Perturb_279_KD_MBNL2_SRP077885	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.04164
BRD-K20435953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39273
BRD-K75293299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76388
BRD-K44139682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37192
KMRC20	CCLE Cell Line Gene Expression Profiles	1.0	1.77991
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30285881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87066
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.3973
BRD-K41026056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36822
Sarcoma_SARC_TCGA-LI-A9QH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91615
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18407
FAM47E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00825581
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1401
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.062985
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841405
Massive Hepatic Necrosis	CTD Gene-Disease Associations	1.0	1.13449
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19027
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06157
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838082
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.940284
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04044
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-410	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54003455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06184
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
carbamazepine-835	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938027
BRD-K12749985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41041
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.32127
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8848
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13417
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04045
BRD-K77173942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34542
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874207
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51075
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1582
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28249
Lung adenocarcinoma_LUAD_TCGA-44-2659-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884354
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20138
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79090631_CGP-60474_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-A26165232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03253
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.05582
BRD-K79090631_CGP-60474_LNCAP_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01503
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10835
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01849
Sarcoma_SARC_TCGA-K1-A3PO-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A90462498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22585
C-75-6423	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.05702
BRD-K14364923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01849
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.13388
GSE128730_0_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAP2K1_knockdown_134_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.78734
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42323
SCS214	DepMap CRISPR Gene Dependency	1.0	3.94491
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CD320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11025
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0662
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971226
enilconazole-3139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5707_KO_Abcc8_ERP119268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70941721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.023
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3405
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A81392774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.98847
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911943
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73371
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21824
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91867
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98986
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00713
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-2.004
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K60053695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26231
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47932
EZH2	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ankyloglossia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31073
BRD-K74632893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19073
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82947
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31616862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16293
NECTIN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00713299
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81219
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1832
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
BRD-K94090114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98483
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867899
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62384
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5998
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE89018_10_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
STK40	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00752021
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.486
BRD-A67787745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51487
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124471,GSE124488_1_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10723
BRD-K84593579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39417
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88286
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
asthma	GWASdb SNP-Disease Associations	1.0	0.679961
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.872163
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sp1_22099172_dental_follicle_cell_gof_human_gpl11532_gse31628	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.481531
BRD-K27109474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38386
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01423
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SSX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063679
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08346
pregnenolone-2497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1156
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63328
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6937
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K98109987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17496
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.07206
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	3.14707
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.94964
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69646
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17786
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ADGRF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054777
BRD-K20245846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13752
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.971328
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLB985	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70268
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895642
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A89947015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21689
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61255
hsa-miR-3672	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60323
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.539897
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.34765
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
valproic acid-2700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.22727
CRCGN008_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23753
STC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00483444
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1847
BRD-K14599588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31165
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0821
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0308
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.83777
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.30635
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31113
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45809
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.129019
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-1226-SM-4GICA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26345
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909916
GTEX-OOBK-0726-SM-3LK5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931128
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43348
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-A64523751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27348
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4601
hsa-miR-583	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K79090631_CGP-60474_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NSD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00452683
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7776
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6444
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5823
hsa-miR-4295	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15704
TALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859026
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901221
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_2_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02238
GSE186124,GSE186128_1_v_0_dnmt3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11454
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04134
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08496
lymph node	HPA Tissue Gene Expression Profiles	-1.0	-0.844262
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38964
UACC62	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4543
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75777
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.07447
ESR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473518
Perturb_14870_KO_PU.1_SRP166067	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0947
asthma	GWASdb SNP-Phenotype Associations	1.0	0.582578
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75497233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12252
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.965636
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878375
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13365
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.03304
Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT4_KO_GDS4823_22_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55923
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3352
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.16505
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934913
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20894
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79368
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94613
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6821
Lung adenocarcinoma_LUAD_TCGA-MP-A5C7-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35027
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K93391478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1416
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09358
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
CLPSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01628
BRD-K87909389_alvocidib_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06146
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.371
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.258236
GSE88819_5_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42719
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44245
Perturb_3899_KO_APC_SRP314475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F5-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01713
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29108
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13966
BRD-K74148702_curcumin_RMUGS_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02898
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11659
REST	ENCODE Transcription Factor Targets	1.0	null
LY-294002-6935	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.0641
BRD-K35407043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06382
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93902
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34618
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900788
NB5	DepMap CRISPR Gene Dependency	1.0	9.82757
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53803
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873612
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.945782
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53646
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00129
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21667
CRCGN015_MCF10A.WT.HP_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1192
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.955641
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.889006
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06421
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8663
ITM2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533244
BRD-K44052748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61037
BRD-K97410356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12909
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32408
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35475
BRD-A46950333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55508
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4662b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.40544
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931449
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886412
Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981517
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7431913-Table_1.xls-Sheet1-TablesS1_Gene_clusters_highly_co-expressed_with_MNX1_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05449
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70315
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57155
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21154
BRD-K41655405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39151
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5348
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0801
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07249
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K01314849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51396
Perturb_6505_KO_PTEN_SRP299373	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.46374
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25886
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74243
GSE148692,GSE148695_2_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Micrognathism	CTD Gene-Disease Associations	1.0	1.06698
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17421
Chromosome 18q deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.51073
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNK10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599578
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91247
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.98958
HS688AT	CCLE Cell Line Gene CNV Profiles	1.0	1.8874
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16762
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE71385_1_v_2_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1624
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879267
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.934477
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27935
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K79090631_CGP-60474_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3484
CBX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00724422
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08207
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70696
CEACAM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00711559
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K11389666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12712
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09253
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.859346
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-0626-SM-3P61E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36422
BRD-K19220233_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE207914_1_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28998
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OSM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495094
BRD-K56884305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02386
GTEX-U3ZN-1826-SM-4DXUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11942
PMC12494973-41467_2025_63880_MOESM1_ESM.pdf-125-ETV6_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.852496
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875114
klf5_18983969_embryonic_stem_cell_lof_mouse_gpl1261_gds3509	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.049172
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937503
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.041579
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03455
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32124229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11458
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27914
TUHR14TKB	CCLE Cell Line Gene Expression Profiles	1.0	2.16224
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20548
AP3B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00863917
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08456
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77443
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-889	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE217378_1_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
18537972-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2748
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897246
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831558
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR183	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507818
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.19937
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	1.96152
GLTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569759
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.04293
hsa-miR-491-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835327
BRD-K46056750_AZD-7762_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35591
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
BRD-K87815532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57695
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08047
immunologic hypersensitivity	GWASdb SNP-Phenotype Associations	1.0	0.293281
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54233340_Dorsomorphin dihydrochloride_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04994
BRD-K69387464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04148
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33710385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.88646
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13662825_dinaciclib_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MU-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Facioscapulohumeral muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.017
Perturb_15776_OE_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.75485
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984009
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.851486
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40699
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-Symbol_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01061
hsa-miR-518a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
gliclazide-2870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14509
GPR12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530587
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05111
BRD4_druginhibition_224_GSE50865	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.22205
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11441
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.23837
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848485
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63892351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17744
terguride-3082	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_13976_KO_H3f3a/H3f3b_ERP109384	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.0835
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.231965
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.645
TPH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00833853
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1431
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14112
BRD-K71486446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57779
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824344
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27645
hsa-miR-524-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43389698_BMS-387032_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K87794979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05988
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
leukocyte disease	GWASdb SNP-Disease Associations	1.0	0.322147
Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954024
BRD-K02749944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92466
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11639
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36095
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	GTEx Tissue Gene Expression Profiles	-1.0	-0.896582
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TARDBP_KD_GDS3730_118_human_HEK293E	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79017
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71056
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K23ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37989
BRD-K52237706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02515
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.146444
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-432	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9349
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26983
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.52237
hsa-miR-4255	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.100179
lateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.973323
FOXA2	ChEA Transcription Factor Targets	1.0	null
PL18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_1_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2793
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.275
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-0.883865
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63242692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97968
BRD-K30312557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6369
obesity	GWASdb SNP-Disease Associations	1.0	0.635081
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9704
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20426
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09955
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828396
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1497
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67627
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CALU3	CCLE Cell Line Gene Expression Profiles	1.0	1.6361
isoflupredone-5545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIRT4_KO_GSE56321_391_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06117
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.866372
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6798-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00734276
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
tamoxifen_homo sapiens_gpl3921_gse33366	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RNASET2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00772461
BRD-A84941884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53266
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4322
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0036
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05553
BRD-K14799424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01372
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13861
BRD-K20416270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72935
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838296
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46073
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bronchial disease	GWASdb SNP-Disease Associations	1.0	0.679961
hsa-miR-299-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2627
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28249
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931509
BRD-K33257311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33893
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88331
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.3283
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.12634
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62683
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73356
GSE113106_0_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcaine-3349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.100179
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930227
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.051705
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.15378
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05267
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53008
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1294
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889115
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20621
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.881345
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6404
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17142
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25426
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17451
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941466
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42877
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31721
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.556
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03064
BRD-K56431031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29397
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27484
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25986
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.17367
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20542
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
BRD-K87909389_alvocidib_LNCAP_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999161
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652261
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.29351
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57139
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7922
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AM38	DepMap CRISPR Gene Dependency	1.0	2.90689
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20626
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.131
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-R55C-0726-SM-48FCN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39667
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AD-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918071
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79321447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00266
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pseudomonas Infection_Lung Tissue_GSE923	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43012
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93887
periventricular stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48644
RUNX2	ChEA Transcription Factor Targets	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914907
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21917
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1376
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50812
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4538	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.05386
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 1 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23054
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28318
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829695
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74613
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8201
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67551
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22114
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1288	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38622
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07482
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K34980742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19578
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38036
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889044
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22611
HT29	CCLE Cell Line Gene Expression Profiles	1.0	1.44292
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
TRUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11313
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24659
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86467
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41203
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82815
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73281
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUW-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968273
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49767
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51539
BV173	CCLE Cell Line Gene CNV Profiles	1.0	1.97564
WB-4101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10856
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42323
BRD-K14442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87126
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1779
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02246
SW48	CCLE Cell Line Gene Expression Profiles	1.0	1.36538
BRD-K46805838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23074
GSE157594_5_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92052
BACH1	ENCODE Transcription Factor Targets	1.0	null
MAP3K7_knockout_246_GSE34417	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.21312
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839009
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991344
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27639
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892012
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997052
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50812
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38055
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5077-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74796
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16686
BRD-K75703503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43364
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04516
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.08337
NDUFA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055946
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15558
hsa-miR-527	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hsa-miR-148a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03813
Lung squamous cell carcinoma_LUSC_TCGA-21-1078-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12063
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	2.17837
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972572
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905035
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40809590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16197
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A43135847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2542
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	2.11213
NCIH2126	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51153
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23678
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21680192_mitoxantrone_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
VAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56775
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4065
BRD-K84992272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71621
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0543
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842757
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
abnormal neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.882984
BRD-K41700289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06794
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54285478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37009
BRD-K28932860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13281
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33081
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21693
TAF1	ENCODE Transcription Factor Targets	1.0	null
INTS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0060542
SCC25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85808
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alzheimer's Disease_Entorhinal cortex_GSE5281	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66691
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45036
GSE200839,GSE233826_2_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0061
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN011_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09353
BRD-K43389698_BMS-387032_MCF7_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71756
BRD-K92484282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3907
GSE157049,GSE157051_6_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64753899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7398
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81218
COLO680N	DepMap CRISPR Gene Dependency	1.0	4.92908
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33194
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839826
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5858
BRD-K40294449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00564
Perturb_8677_KD_KLF11_SRP044756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.9666
DOT1L_DELETION_GDS4295_427_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 5 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55763052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79412
pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.163046
BRD-A23955117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07676
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987586
ACTA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554798
BRD-K44643967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2469
(+/-)-catechin-4255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFYC_NFYC	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-423	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K75038114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44317
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95475
EWSR1	ChEA Transcription Factor Targets	1.0	null
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52725
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DJ-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22739
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47873
pancreatic adenocarcinoma	GWASdb SNP-Phenotype Associations	1.0	0.684849
GTEX-P4PQ-1526-SM-3NMCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886207
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.011728
ME-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28699
obstructive lung disease	GWASdb SNP-Disease Associations	1.0	0.372451
BRD-K23442578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37546
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.37496
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13525
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17144037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28546
BRD-K52468958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34852
CC2D2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515101
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76679
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31548
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884765
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1594
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TT2609-C02	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09514
BRD-K53903639_480743.cdx_JHUEM2_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2661
BRD-K67177501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34749
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-1126-SM-3P615	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28391
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_ALL-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22418
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K83183132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2875
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827617
BRD-K00767817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35416
HT115	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49713
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08904
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GSE93309_1_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70854630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09351
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87909389_alvocidib_MCF7_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dihydroergotamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39896
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62004
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6799
Nerve plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12069
appendix	HPA Tissue Gene Expression Profiles	-1.0	-0.83887
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37228
pipenzolate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68329
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4803-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87909389_alvocidib_HME1_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61516
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Eosinophils	dbGAP Gene-Trait Associations	1.0	0.064818
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02285
PEO4	DepMap CRISPR Gene Dependency	1.0	2.79607
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16447
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25075
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73635724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29744
HPAF-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.94099
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-GeneID_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
NO10	DepMap CRISPR Gene Dependency	1.0	10.0831
SCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54813
PKM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673389
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	2.51377
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20687
SCC-25	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.83684
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14501_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.16904
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACKR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574428
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38615104_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4666-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2903
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurodegenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08365
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02301426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21729
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33194
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4885
GSE205021_3_v_1_fenofibrate_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828906
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZP-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9380_KO_lincRNAEPS_SRP354143	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.092072
GPR22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615853
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20402
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.03604
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12835
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23093
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09958
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55171585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36958
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994323
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.877686
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.80643
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51825
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OV-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6792
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7842-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0989
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.886486
BRD-K33283629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12583
BRD-K81544427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55038
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.81517
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39905
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61899
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847728
YD10B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3822
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
immune system disease	GWASdb SNP-Disease Associations	1.0	0.053362
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8793
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23583
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71328
BRD-K10412976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8283
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946488
BRD-K23430426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03197
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15703
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9558
hsa-miR-3666	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
D423MG	DepMap CRISPR Gene Dependency	1.0	2.34833
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53002
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20542
TUBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29989
BRD-K17743125_S1085_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inner CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960483
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34004579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91015
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A81260764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1484
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10449
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of eosinophils	GWASdb SNP-Phenotype Associations	1.0	0.582578
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14245
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15273
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47173
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19227686_PHENOLPHTHALEIN_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.42005
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.091985
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04863
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35202
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93317
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48039
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41934
SIRT4_KO_GDS4823_505_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51094
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827252
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8259
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34007
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22152
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6574
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73186
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36727
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875213
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9302
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30409
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903636
SK-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881105
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953371
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.72055
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845636
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48122
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51666223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19942
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-0.788556
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2510_KD_EIF4A1_SRP042616	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.04734
Hypercholesteremia_Hepatic Tissue_GSE3889	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.8897
BCL9L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0043682
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21885
NB6	DepMap CRISPR Gene Dependency	1.0	7.48938
QIMR-WIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27731
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7764
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12831
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00831
CHMP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00432568
BRD-K58140298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03567
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13390322_AT-7519_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22189
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03618
BRD-K85907501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0546
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV4	DepMap CRISPR Gene Dependency	1.0	5.42466
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14502
GATA2	ENCODE Transcription Factor Targets	1.0	null
liver	HPA Tissue Gene Expression Profiles	1.0	1.10885
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04498687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47619
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77482
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16701
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A63759745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4367
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.807954
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43253
BRD-K80568112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62777
BRD-K71563254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20527
BRD-K53417444_OTSSP167_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K49371609_528116.cdx_A549_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
BRD-K73730918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01426
BRD-K15992638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45532
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960713
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14709
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6244
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23453
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01794
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15055
PPIG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555935
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_4day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.71694
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18936
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3242
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CYP2C9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556885
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16329
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GSE112995,GSE132079_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99755021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35581
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14871
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37363
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.54951
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0015
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39745
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr4_186190511_A_C_b38	GTEx eQTL 2025	1.0	2.27269
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17759
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55228
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0012
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944501
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831558
A-61603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4441
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21808
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5242
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90347
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9165
CRCGN016_MCF10A.WT.HP_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55182
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-7775-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.645
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_Targets-Unnamed_9_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.66696
BRD-K10540354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34252
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13814
Perturb_13714_KO_ASXL3_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.78024
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66115
ZNF263	ENCODE Transcription Factor Targets	1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0507
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922082
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.946283
PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06126
MYC	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09849
Septic Shock_Whole blood_GSE9692	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.41697
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NRIP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00920753
GATA3-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12228
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92224
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941257
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14414396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79158
BRD-K39985369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10606
BRD-K05350978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32735
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929946
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.51624
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Popliteal pterygium syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09235
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHLA15	DepMap CRISPR Gene Dependency	1.0	3.59993
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21083
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94623
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00814
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19601
chrysin-6485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893212
BRD-K49328571_dasatinib_MCF7_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3571
PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-DANG_BOUND_BY_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12949
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30478
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4993
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19114
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03347
PSTPIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513056
BRD-A10134527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61029
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6869
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A76904477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45234
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5190-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89562681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03462
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27398
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919333
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K96979108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09356
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952884
BRD-K87530935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70084
Perturb_16745_KO_Ncor2_ERP131241	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40701
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.123757
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989665
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2972
BRD-K42650945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37688
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83133
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911825
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57272
hsa-miR-4252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55217
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974423
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15894
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63837
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.363089
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K08751619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50572
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08278
Prostate adenocarcinoma_PRAD_TCGA-G9-6332-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01449
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31163
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A25687296_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959293
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
Corneal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07756
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21331
Posterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11163
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCAR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00914276
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF891	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15305
abnormal motor neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.882984
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10418
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991124
BRD-K10232513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28519
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19242
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18847
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45377
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935553
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31348
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28943
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01201
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7221_KO_EZH_SRP321650	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SETDB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502821
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47473
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867488