association dataset threshold value standardized value KOSC-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2693-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LK-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKG-IIIA COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7222-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-0011-R4A-SM-2S1QL GTEx Tissue Sample Gene Expression Profiles 1.0 1.02487 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055371 Lung squamous cell carcinoma_LUSC_TCGA-60-2703-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCPAP CCLE Cell Line Gene Expression Profiles -1.0 -2.46423 KD DepMap CRISPR Gene Dependency 1.0 2.20667 CLDN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18135 H3K9me3_Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Psoriasis vulgaris_Skin tissue_GSE14905 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.71031 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12193 H3K9me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-0011-R2A-SM-32QOW GTEx Tissue Sample Gene Expression Profiles 1.0 0.871176 respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.244345 mRNA_ASCL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEx Brain 20-29 vs 70-79 GTEx Tissue-Specific Aging Signatures 1.0 17.0536 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.92894 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.993748 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.03975 em2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.409 GSE157555,GSE157556_4_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09235 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03782 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.68204 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7504 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.26909 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.81155 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.04384 GSE216538_1_v_4_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE70935_2_v_4_cyfip1_human RummaGEO Gene Perturbation Signatures -1.0 null VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37036 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0348 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5247-01A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL62 CCLE Cell Line Gene CNV Profiles -1.0 -1.97044 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.11289 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.68125 496100315_TCx_no dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.01937 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.10978 GTEX-QVJO-0011-R2A-SM-2S1QK GTEx Tissue Sample Gene Expression Profiles 1.0 0.930548 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46964 Chromatoid body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.851 AR ChEA Transcription Factor Targets 1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.68098 bone marrow HPA Tissue Protein Expression Profiles 1.0 1.6166 GSE199541_2_v_5_mbd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X585-0011-R1B-SM-46MVE GTEx Tissue Sample Gene Expression Profiles 1.0 1.09935 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.887326 TPRA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81793 PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-OLIG2-M_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.1339 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50461 SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19245 NCI-H250 COSMIC Cell Line Gene Mutation Profiles 1.0 null ST486 COSMIC Cell Line Gene Mutation Profiles 1.0 null NY COSMIC Cell Line Gene Mutation Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29502 EW-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null UPCISCC200 DepMap CRISPR Gene Dependency 1.0 2.40426 amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.931861 QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.891857 NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5484 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.52224 HCC4006 CCLE Cell Line Gene CNV Profiles 1.0 1.52802 Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.1852 PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XMD1-0011-R3B-SM-4AT5R GTEx Tissue Sample Gene Expression Profiles 1.0 0.830693 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.889017 A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13549 HCC827GR5 CCLE Cell Line Gene Expression Profiles 1.0 1.466 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22066 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.64773 GTEX-X261-0011-R5A-SM-3NMB4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.839635 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.09654 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.31338 SNU503 CCLE Cell Line Gene CNV Profiles 1.0 1.86784 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0333 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03392 Limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 orbital frontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04074 SNU886 CCLE Cell Line Gene Expression Profiles -1.0 -1.85113 GSE261563_0_v_1_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9823 HCC1395 CCLE Cell Line Gene CNV Profiles 1.0 1.86389 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37736 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42698 IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68149 STAT3-20064451-CD4+T-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.902067 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04073 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.03131 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.88921 pyramidal layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34373 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.62695 Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.0803 HS766T COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42236 Internal female genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.641 FADU DepMap CRISPR Gene Dependency 1.0 2.91057 GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.874862 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.74126 NCIH2141 CCLE Cell Line Gene Expression Profiles 1.0 2.40772 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.5305 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13549 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30102 PMC3342315-pone.0036054.s011.xlsx-overlap_PBX1_ChIP_siRNA-Unnamed_6_PBX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-P44H-0011-R8A-SM-2XCEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.10109 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058182 MEIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9476 fulvestrant_homo sapiens_gpl570_gse22533 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19429 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.255 NIHOVCAR3 CCLE Cell Line Gene Expression Profiles 1.0 1.56193 Rectum adenocarcinoma_READ_TCGA-F5-6863-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7311 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.828656 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.80234 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.15053 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null RCHACV DepMap CRISPR Gene Dependency 1.0 3.19334 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11588 GSE203308_9_v_10_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE178714_6_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2467 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-488-GMEB1_GMEB1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X4XX-3026-SM-3NMB2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.881533 RCC10RGB DepMap CRISPR Gene Dependency 1.0 4.47977 Perturb_2620_KD_ESR1_SRP266979 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.00186 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.992989 NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-4699-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.32519 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.999252 ONCODG1 CCLE Cell Line Gene Expression Profiles 1.0 1.91076 Acute Myeloid Leukemia_LAML_TCGA-AB-2846-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cul5-RING ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.845 NCIH522 DepMap CRISPR Gene Dependency 1.0 2.62508 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.68421 CA4 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.910258 PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NEUROD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1845 EJM DepMap CRISPR Gene Dependency 1.0 4.36749 CHST15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03008 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.63757 IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F1 JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.61564 GTEX-PWO3-0011-R3A-SM-2I5EX GTEx Tissue Sample Gene Expression Profiles 1.0 0.904055 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01294 VMRCLCP CCLE Cell Line Gene Expression Profiles 1.0 1.56082 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.675 RBM14_02_03 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.60334 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.934245 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null NEC8 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X4XX-0011-R5A-SM-46MWN GTEx Tissue Sample Gene Expression Profiles 1.0 0.948518 Cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AE-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.74943 Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.131 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14676 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.861198 GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 0.988736 H4K5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.02225 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWO3-0926-SM-2I5EY GTEx Tissue Sample Gene Expression Profiles 1.0 1.07079 Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04212 dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.78892 PRR19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75418 methylphenidate_mus musculus_gpl11180_gse33619 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null 496100556_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.06932 primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02091 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Endometrial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.136 GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.962068 KNS81 CCLE Cell Line Gene CNV Profiles -1.0 -1.42671 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0486 fallopian tube GTEx Tissue Gene Expression Profiles 1.0 0.85679 GTEX-RNOR-0011-R4A-SM-3GAD3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00865 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.88463 dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.840542 GTEX-P44H-0011-R5A-SM-2XCEX GTEx Tissue Sample Gene Expression Profiles 1.0 0.842177 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.7195 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.958287 outer CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.983542 GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 0.885484 GSE238005_0_v_3_c9orf72_human RummaGEO Gene Perturbation Signatures -1.0 null LN319 DepMap CRISPR Gene Dependency 1.0 2.34147 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.978594 NAMALWA COSMIC Cell Line Gene Mutation Profiles 1.0 null LAN2 DepMap CRISPR Gene Dependency 1.0 2.46077 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.96877 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.74153 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38748 MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.348 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.51136 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NL4W-0011-R5a-SM-2I3GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.03799 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.12562 GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles 1.0 1.02247 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-4717-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31151 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.875269 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-661 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 D-245MG COSMIC Cell Line Gene Mutation Profiles 1.0 null hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.16149 GSE142684_3_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null SARS-dORF6_60Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.58725 SNU398 DepMap CRISPR Gene Dependency 1.0 2.66943 TP63 ChEA Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.985783 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03392 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.23122 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE114992,GSE114993_7_v_3_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-NL4W-0011-R4a-SM-2I5GZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02341 NCIH2228 CCLE Cell Line Gene Expression Profiles -1.0 -2.01801 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6163 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.885378 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.74866 basolateral nucleus (basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.855802 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.60808 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12612227-41523_2025_836_MOESM1_ESM.pdf-112-RARA-AS1_RARA Rummagene Transcription Factor Associations 2026 1.0 null MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.939251 mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_37_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null H3K9me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lymphangioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.138 TUHR4TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.42904 RNF208 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76581 orbital frontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54836 K029AX CCLE Cell Line Gene CNV Profiles -1.0 -1.46526 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2753-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.64601 TE-10 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 BLUE1 DepMap CRISPR Gene Dependency 1.0 2.0165 H3K9me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X261-0011-R7A-SM-4E3JJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.897998 NFYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8056 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990567 Lung-respiratory mucous cell Tabula Sapiens Gene-Cell Associations 1.0 -0.0164095 SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62752 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.59215 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0011-R1B-SM-4B65C GTEx Tissue Sample Gene Expression Profiles 1.0 0.99727 Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC3342315-pone.0036054.s011.xlsx-overlap_PBX1_ChIP_siRNA-Unnamed_5_PBX1 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DIS3L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22303 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.926102 dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14662 hsa-miR-3688-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.63085 SNU61 DepMap CRISPR Gene Dependency 1.0 2.49578 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70445 EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SW1271 CCLE Cell Line Gene Expression Profiles -1.0 -2.49851 MAFA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9041 PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE157555,GSE157556_4_v_7_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.47871 496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.89425 superior occipital gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.863079 HT-29 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100573_HIP_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.92988 GSE178714_3_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HM-01A-12R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 85.5026 HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956391 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.43216 PC-9 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.61 GSE162590_1_v_0_gsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null superior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.880481 GTEX-XMD1-0011-R6A-SM-4AT5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.928989 amygdaloid complex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52882 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.65087 MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.939976 FOS ENCODE Transcription Factor Targets 1.0 null GTEX-NL4W-0011-R10A-SM-2I3DY GTEx Tissue Sample Gene Expression Profiles 1.0 1.12541 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.894389 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.56532 GSE142684_4_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.973187 CADO-ES1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.844748 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.1791 496100390_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18808 substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18023 NCIH1930 CCLE Cell Line Gene Expression Profiles -1.0 -2.44531 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.63101 Lung adenocarcinoma_LUAD_TCGA-05-4425-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO680N CCLE Cell Line Gene CNV Profiles 1.0 1.62585 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE119345_2_v_3_bexarotene_human RummaGEO Drug Perturbation Signatures -1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.922698 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Colon adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.372 GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00389 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1367 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.86417 H9 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37984 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.04891 Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3657 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31954 GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.00122 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Ovary TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KIJK DepMap CRISPR Gene Dependency 1.0 2.64406 Cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.733 SW 48 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04332 GTEX-NL3H-0011-R4a-SM-2I3GK GTEx Tissue Sample Gene Expression Profiles 1.0 0.865419 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5347 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null amygdaloid complex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.67208 NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.50127 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.880979 peripheral blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.235167 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25497 GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.83905 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.852953 MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.948461 Lung squamous cell carcinoma_LUSC_TCGA-21-A5DI-01A-31R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHOM1 CCLE Cell Line Gene Expression Profiles -1.0 -2.00312 LOUNH91 CCLE Cell Line Gene CNV Profiles -1.0 -1.33332 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921831 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.831401 TCF7L2 ENCODE Transcription Factor Targets 1.0 null Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0014 GTEX-WVLH-0011-R2A-SM-3MJFJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.83116 NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7705 pancreas GTEx Tissue Gene Expression Profiles -1.0 -0.845735 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles 1.0 0.967291 primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.874388 Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MR-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1304 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22183 GTEX-QMR6-0011-R1A-SM-32PKW GTEx Tissue Sample Gene Expression Profiles 1.0 0.827481 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10582 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.989999 LENG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4806 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17664 Asthma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.879378 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.68395 CORL279 DepMap CRISPR Gene Dependency 1.0 7.69238 cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.935353 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.826052 GTEX-QDT8-0011-R8A-SM-32PKE GTEx Tissue Sample Gene Expression Profiles 1.0 1.0048 amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.78935 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29R-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3 MotifMap Predicted Transcription Factor Targets 1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7889 H3K9me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7224 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4037 internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.872322 Brain Lower Grade Glioma_LGG_TCGA-DU-6405-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C-33 A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.891857 CAPAN1 CCLE Cell Line Gene Expression Profiles -1.0 -3.18347 BBS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72138 amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05389 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08886 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.85529 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HT-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intramuscular adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.977 OVKATE CCLE Cell Line Gene Expression Profiles 1.0 1.71262 hsa-miR-663b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 KMOE-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null SKRC31 DepMap CRISPR Gene Dependency 1.0 2.93184 GSE217071_3_v_0_ythdf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.928263 dorsal motor nucleus of the vagus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06877 primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22759 Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.81069 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE178714_6_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RU72-0011-R5A-SM-2TF6U GTEx Tissue Sample Gene Expression Profiles 1.0 0.892382 GSE123502,GSE123504_1_v_0_chd4_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.23887 496100570_HIP_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.11915 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29254 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.69052 ES-WA7 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.33878 dentate (lateral) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.909779 LN319 CCLE Cell Line Gene Expression Profiles 1.0 2.02808 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.895708 GSE210580_3_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Endometritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 Procentriole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.831 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7871 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZF-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC0504 DepMap CRISPR Gene Dependency 1.0 3.38239 H3K9me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957688 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.860438 GSE195559_2_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1 Rummagene Transcription Factor Associations 2026 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.968751 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.64258 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU81 CCLE Cell Line Gene Expression Profiles -1.0 -1.90221 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.61967 chr14_93916616_G_C_b38 GTEx eQTL 2025 1.0 3.07783 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.85756 cuneus, left, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.961401 NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 1.47162 GTEX-QVJO-0011-R9A-SM-2S1QH GTEx Tissue Sample Gene Expression Profiles 1.0 0.840701 H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12084 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.883553 GSE199541_2_v_4_mbd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PC14 CCLE Cell Line Gene CNV Profiles -1.0 -3.20163 UMUC1 DepMap CRISPR Gene Dependency 1.0 2.30395 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-80-5608-01A-31R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61883 NZOV9 DepMap CRISPR Gene Dependency 1.0 10.2632 GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.00094 Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.61638 ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1764 bronchial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.435275 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10638 ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11706 Growth hormone receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.733 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7537 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.858174 Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61617 NCIH1694 CCLE Cell Line Gene CNV Profiles 1.0 2.17344 HCC515 DepMap CRISPR Gene Dependency 1.0 2.86195 MERO14 DepMap CRISPR Gene Dependency 1.0 4.20831 RCOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73592 hippocampus (hippocampal formation)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.02466 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.8763 NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.61306 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29254 Breast Cancer_Mammary Gland Tissue_GSE3744 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.34368 GSE156923_2_v_3_rbmx_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.76818 GTEX-XLM4-0011-R10A-SM-4AT5P GTEx Tissue Sample Gene Expression Profiles 1.0 0.829299 TLX1::NFIC MotifMap Predicted Transcription Factor Targets 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88871 GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 0.877053 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.928313 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.8768 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21396 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921831 BL41 CCLE Cell Line Gene Expression Profiles 1.0 1.35634 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40894 PMC12047497-mmc5.xlsx-Sheet1-GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP_HNF1A Rummagene Transcription Factor Associations 2026 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19474 JL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.4218 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30277 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0394 PMC11574045-44318_2024_257_MOESM4_ESM.xlsx-Sheet1-Dataset_EV2_TEAD4-interacting_proteins_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null Mafg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.6774 OSC-19 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.879378 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.48935 CA1 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.91586 PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53 Rummagene Transcription Factor Associations 2026 1.0 null superior occipital gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.876122 CAKI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7868 GSE169155_6_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.895748 H3K9me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Testis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05587 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.39818 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null U-251MG cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.917 NECTIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50243 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6951-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-0011-R6A-SM-3DB7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.886962 CEBPZ_02_118 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.64981 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.72021 Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Atf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.7268 ERG ChEA Transcription Factor Targets 1.0 null Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.1015 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.23088 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01565 GTEX-N7MT-0011-R5a-SM-2I3G6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03446 ADAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21504 GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 0.860049 GSE130217_0_v_3_sesn2_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.6343 GTEX-PWO3-0011-R5A-SM-2I5EZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.829356 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.89669 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18698 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWO3-0011-R2A-SM-2S1OX GTEx Tissue Sample Gene Expression Profiles 1.0 0.87822 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.67265 Cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.57599 asthma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.45447 DMS79 CCLE Cell Line Gene Expression Profiles 1.0 2.13777 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.4919 levodopa_rattus norvegicus_gpl4135_gse43375 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-524-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.937619 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6513 SKMEL1 CCLE Cell Line Gene CNV Profiles -1.0 -2.59494 H2AC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88283 NCI-H1694 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.86417 Gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 hsa-miR-3145-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 SF172 CCLE Cell Line Gene Expression Profiles 1.0 1.3505 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.15053 TIRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6991 GSE128333_4_v_0_tcf4_human RummaGEO Gene Perturbation Signatures 1.0 null SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61617 COV318 CCLE Cell Line Gene Expression Profiles 1.0 1.77056 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.69779 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943078 primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0144 VMRCRCW CCLE Cell Line Gene CNV Profiles -1.0 -1.98322 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19704 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2466 Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.733 GTEX-WL46-0011-R2A-SM-3LK6O GTEx Tissue Sample Gene Expression Profiles 1.0 0.86049 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0348 PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WHSE-0011-R2A-SM-3P5ZL GTEx Tissue Sample Gene Expression Profiles 1.0 0.835501 FOS JASPAR Predicted Transcription Factor Targets 1.0 null Cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.926102 MG-63 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE129389_0_v_7_tropifexor_mouse RummaGEO Drug Perturbation Signatures 1.0 null EM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.39193 MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.879474 Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.0273 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5931 H3K9me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.15315 Hippocampus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.933035 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0348 GTEX-QDT8-0011-R6A-SM-32PKI GTEx Tissue Sample Gene Expression Profiles 1.0 0.985606 MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6932 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08821 GSE114992,GSE114993_0_v_11_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_13819_KO_YBX1_SRP222969 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.63664 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.037 ST486 DepMap CRISPR Gene Dependency 1.0 3.27251 NCIH520 CCLE Cell Line Gene Expression Profiles -1.0 -1.50465 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.70538 Perturb_2174_KO_Nlrp3_SRP366634 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.56698 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.23833 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Q2AH-0426-SM-2I3EP GTEx Tissue Sample Gene Expression Profiles 1.0 0.893907 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4991_KO_Mettl5_SRP268611 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.13107 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6962 OC314 DepMap CRISPR Gene Dependency 1.0 4.20345 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.53338 Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3129 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.62395 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.76092 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.848342 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68525 FUOV1 CCLE Cell Line Gene CNV Profiles 1.0 1.86859 GSE124375_10_v_9_chd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IPC-298 COSMIC Cell Line Gene Mutation Profiles 1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61617 hsa-miR-4527 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43438 precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.896946 Reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.853546 Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6983-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null Cul7-RING ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.07 Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1569 RKO CCLE Cell Line Gene Expression Profiles 1.0 1.38681 NSUN5P2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68219 Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42236 Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intracellular anatomical structure COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3434 FADU CCLE Cell Line Gene CNV Profiles 1.0 3.27851 inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882005 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.49644 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.75068 GSE229978_4_v_7_morphine_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.82411 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.08862 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.89207 DHRS11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68864 LRF MotifMap Predicted Transcription Factor Targets 1.0 null outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.927793 Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83607 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11991 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04073 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.49276 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.973189 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.54753 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.4618 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 GSE143743_0_v_2_c9orf72_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QDVN-0726-SM-4B64L GTEx Tissue Sample Gene Expression Profiles 1.0 0.950383 RCM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03392 TE10 CCLE Cell Line Gene CNV Profiles 1.0 1.84429 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22054 Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1274 TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9328 GTEX-X4XX-0011-R3B-SM-46MWK GTEx Tissue Sample Gene Expression Profiles 1.0 0.945646 U118MG CCLE Cell Line Gene Expression Profiles -1.0 -1.53946 Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HD-MY-Z COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6 Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.5999 YAMATO DepMap CRISPR Gene Dependency 1.0 2.72599 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62313 496100438_PCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.5016 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.94434 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.567 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null eosinophil TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.724453 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 1.9546 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.59645 GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles 1.0 0.96707 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null GSE157777_2_v_0_foxa3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X4XX-0011-R6B-SM-46MWP GTEx Tissue Sample Gene Expression Profiles 1.0 0.899233 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.79455 Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20244 ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.50906 hsa-miR-511 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.64318 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.82142 H3K9me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71088 SNU601 CCLE Cell Line Gene CNV Profiles -1.0 -1.85751 GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23252 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.63762 GSE205332_1_v_0_queuine_human RummaGEO Drug Perturbation Signatures -1.0 null TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Grm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.722 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.46199 OVCA420 COSMIC Cell Line Gene Mutation Profiles 1.0 null mRNA_STAT3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Cerebellum BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.04556 SK-HEP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.81196 GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 1.07797 HSC3 DepMap CRISPR Gene Dependency 1.0 2.27512 H3K9me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.833233 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71387 ADNP-35650610-MESC-MOUSE-STEM-AUTISM ChEA Transcription Factor Targets 2022 1.0 null SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.36886 SRSF7_02_89 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.61586 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.58494 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null fallopian tube HPA Tissue Gene Expression Profiles 1.0 1.4569 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07871 EZH2 ENCODE Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F6-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE6 CCLE Cell Line Gene CNV Profiles 1.0 1.94238 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13549 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29068 PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD Rummagene Transcription Factor Associations 2026 1.0 null HS683 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.32456 GSE153836_11_v_9_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_15286_KO_Trp73_SRP067006 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.07364 PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_PRDM6 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.902791 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null HS746T COSMIC Cell Line Gene Mutation Profiles 1.0 null SRF JASPAR Predicted Transcription Factor Targets 1.0 null YT COSMIC Cell Line Gene Mutation Profiles 1.0 null JIMT1 CCLE Cell Line Gene CNV Profiles -1.0 -2.35126 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882697 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.0425 Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5453 LOU-NH91 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11649 PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC Rummagene Transcription Factor Associations 2026 1.0 null GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 GSE159728,GSE159730_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-X261-0011-R6B-SM-4E3J8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03954 GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 0.826165 MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1871 BCL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98631 JHUEM7 DepMap CRISPR Gene Dependency 1.0 5.27709 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11876 CORL47 DepMap CRISPR Gene Dependency 1.0 2.46759 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null AGS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13549 GMEB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49397 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.733 GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.52935 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.85714 GSE157777_2_v_3_foxa3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.297 Colorectal adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.264077 hsa-miR-4261 TargetScan Predicted Conserved microRNA Targets 1.0 0.293524 RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0435 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.21933 GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 0.891337 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.82579 GSE200352_9_v_6_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null basomedial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09121 EJM CCLE Cell Line Gene CNV Profiles 1.0 2.59542 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.626 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42719 GSE178714_1_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0143 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11706 primary motor-sensory cortex (samples)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38805 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.20948 SLU7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10788 Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.7826 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35687 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.58805 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.26026 HHV-8_72Hour_18587055_GSE6489 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.2165 TE5 DepMap CRISPR Gene Dependency 1.0 2.26214 KARPAS-422 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24351 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6299 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-TSE9-0011-R4A-SM-3DB7H GTEx Tissue Sample Gene Expression Profiles 1.0 0.874763 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18822 LN443 CCLE Cell Line Gene CNV Profiles 1.0 1.34581 GTEX-WHSE-0011-R3A-SM-3P5ZM GTEx Tissue Sample Gene Expression Profiles 1.0 1.06956 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29148 TPD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01025 GTEX-X585-0011-R4B-SM-46MVH GTEx Tissue Sample Gene Expression Profiles 1.0 1.06039 GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles 1.0 0.902292 Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alzheimer Disease DisGeNET Gene-Disease Associations 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.88544 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.29769 DMS79 CCLE Cell Line Gene CNV Profiles 1.0 1.57057 Female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 GSE261563_9_v_1_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70021 Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intestinal benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.138 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921725 AP-4 MotifMap Predicted Transcription Factor Targets 1.0 null Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.9679 GSE178714_5_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2961 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.57348 SF268 CCLE Cell Line Gene CNV Profiles 1.0 1.57361 Melancholic depression DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.733 496100405_TCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16179 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.50418 SNU899 CCLE Cell Line Gene Expression Profiles 1.0 3.10462 mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05724 AGXT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49361 outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.89238 GTEX-RVPV-0011-R3A-SM-2TF63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.830017 GSE178714_1_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WU-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NO11 DepMap CRISPR Gene Dependency 1.0 5.25953 GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles 1.0 0.948228 GSE131377_1_v_0_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.08887 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 67.6086 ARL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05259 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921831 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09796 HOP92 CCLE Cell Line Gene CNV Profiles -1.0 -1.33718 NCIH2141 CCLE Cell Line Gene CNV Profiles 1.0 2.00625 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210580_4_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71159 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.56781 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.891857 Perturb_10616_KO_Ttn_SRP136441 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.88528 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7263 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921831 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8558 L363 CCLE Cell Line Gene CNV Profiles -1.0 -1.52364 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE95688_7_v_2_glutathione_mouse RummaGEO Drug Perturbation Signatures 1.0 null outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03623 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRN-2426-SM-2I5EQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.05856 GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles 1.0 0.839716 THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0659 JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36797 EW8 CCLE Cell Line Gene Expression Profiles 1.0 1.4203 GSE70935_3_v_4_cyfip1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles 1.0 0.999222 primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.64574 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 496100323_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.97836 SETDB1_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Buccal epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.784 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.934623 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.89189 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE199255,GSE199356_0_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41146 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1212 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0348 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00008 MON DepMap CRISPR Gene Dependency 1.0 5.64825 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41708 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.48608 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5FO-01A-21R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.976072 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.55872 chr14_93932437_G_A_b38 GTEx eQTL 2025 1.0 2.14838 Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLCPRF5 DepMap CRISPR Gene Dependency 1.0 2.03729 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17547 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.828937 mRNA_TUBA1A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-XGQ4-0826-SM-4AT4T GTEx Tissue Sample Gene Expression Profiles 1.0 0.845027 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.20577 Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.343 Brain Lower Grade Glioma_LGG_TCGA-FG-A70Z-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3514 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040758 SNU1076 CCLE Cell Line Gene CNV Profiles 1.0 1.3666 GTEX-UJMC-0726-SM-3GADX GTEx Tissue Sample Gene Expression Profiles 1.0 0.884337 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14798 LSM12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55621 PANC-04-03 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10105 Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Major depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.733 GSE210580_3_v_2_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13795 posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.48947 TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6217 496100451_TCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.39975 MAZ ENCODE Transcription Factor Targets 1.0 null K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35687 Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE87615_1_v_3_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0212 supraoptic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.956257 SMAD4 ChEA Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6983-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80356 GTEX-S7SE-0011-R1A-SM-2XCDE GTEx Tissue Sample Gene Expression Profiles 1.0 0.986047 GSE178714_1_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.89396 PMC7304190-13229_2020_355_MOESM18_ESM.xlsx-Supplemental_Table_5-iPSC_NPCs_TCF4_TCF4 Rummagene Transcription Factor Associations 2026 1.0 null GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2898 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3116 GTEX-NL4W-0011-R6a-SM-2I3GA GTEx Tissue Sample Gene Expression Profiles 1.0 0.844746 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE153836_11_v_2_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE157960_2_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null BECKER DepMap CRISPR Gene Dependency 1.0 3.5512 SCC25 CCLE Cell Line Gene Expression Profiles -1.0 -1.60654 GSE164494_0_v_2_rab22a_mouse RummaGEO Gene Perturbation Signatures -1.0 null striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.974634 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35687 GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 0.924788 HOP-92 COSMIC Cell Line Gene Mutation Profiles 1.0 null brain GTEx Tissue Gene Expression Profiles 1.0 1.4591 TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7548 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2602 striatum_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23385 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.58064 Brain - Spinal cord (cervical c-1) GTEx Tissue Gene Expression Profiles 2023 1.0 1.19723 PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null PBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6667 Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPIP5K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50307 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04497 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01581 GSE171401_1_v_0_adnp_mouse RummaGEO Gene Perturbation Signatures -1.0 null obstructive lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.394491 GTEX-N7MT-0011-R4a-SM-2I3G9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.831124 muscle GTEx Tissue Gene Expression Profiles 1.0 0.849508 Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_U2OS_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12288 OVSAHO CCLE Cell Line Gene Expression Profiles 1.0 1.9708 central nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.825406 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.860438 HCE4 DepMap CRISPR Gene Dependency 1.0 3.47344 EBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.2494 LB831-BLC COSMIC Cell Line Gene Mutation Profiles 1.0 null PBX1 ChEA Transcription Factor Targets 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41146 Npas2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1765 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1436 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.929843 A101D CCLE Cell Line Gene Expression Profiles -1.0 -1.59613 HS936T DepMap CRISPR Gene Dependency 1.0 2.36573 SYCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13939 COLO684 DepMap CRISPR Gene Dependency 1.0 2.15254 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17799 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36629 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055708 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948553 Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Testicular somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.673 GTEX-RM2N-1626-SM-2TF5N GTEx Tissue Sample Gene Expression Profiles 1.0 0.850948 GSE180185_9_v_5_setbp1_human RummaGEO Gene Perturbation Signatures 1.0 null NCIH1184 CCLE Cell Line Gene Expression Profiles 1.0 1.65964 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8436 GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24893 NB1 DepMap CRISPR Gene Dependency 1.0 2.72577 striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.980134 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.855827 PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_AND_UM51_MSC Rummagene Transcription Factor Associations 2026 1.0 null GSE157960_0_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WVLH-0011-R4A-SM-3MJFS GTEx Tissue Sample Gene Expression Profiles 1.0 1.0402 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6195 MAFF ENCODE Transcription Factor Targets 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null CA1 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0996 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 47.5614 SUDHL5 DepMap CRISPR Gene Dependency 1.0 7.12096 MAFK ENCODE Transcription Factor Targets 1.0 null posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19839 posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.55381 Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35149 EP300_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.84425 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66205 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.02084 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SMAD4-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.58895 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TTC549 DepMap CRISPR Gene Dependency 1.0 2.58283 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.828365 MELJUSO CCLE Cell Line Gene CNV Profiles -1.0 -1.8206 GTEX-QVUS-0011-R4A-SM-3GAE7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.853359 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12622 BICR16 CCLE Cell Line Gene CNV Profiles 1.0 2.1425 thyroid gland HPA Tissue Gene Expression Profiles 1.0 0.969172 ZNF876P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93129 NH-12 COSMIC Cell Line Gene Mutation Profiles 1.0 null Gastrointestinal system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.014 SETDB1 ENCODE Transcription Factor Targets 1.0 null C19orf25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05957 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07176 UMUC14 DepMap CRISPR Gene Dependency 1.0 2.31023 cortico-medial group, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20423 SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.7103 GTEX-PWO3-0011-R1A-SM-2I5EW GTEx Tissue Sample Gene Expression Profiles 1.0 0.981105 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921725 GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02676 A704 CCLE Cell Line Gene CNV Profiles -1.0 -1.75616 primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.17286 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XX-0011-R1B-SM-3P622 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05713 Cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Crx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.6333 Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.31665 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.0016 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.38176 G84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52458 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MTF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0253 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5319 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.98732 U138MG CCLE Cell Line Gene CNV Profiles -1.0 -2.06035 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A5R5-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HLC1 CCLE Cell Line Gene Expression Profiles 1.0 2.25314 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.65975 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.01733 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04212 Cellular anatomical entity COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23038 JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17227 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01294 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55E-0011-R4A-SM-2TC5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.824609 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.845106 KNS42 CCLE Cell Line Gene Expression Profiles 1.0 2.67741 Lung adenocarcinoma_LUAD_TCGA-44-2665-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GCM2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6546 NCIN87 DepMap CRISPR Gene Dependency 1.0 3.07219 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.71965 GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 0.869533 HCV_8week+IFN-a_None_GSE37715 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.65539 caudal group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.904176 amygdalostriatal transition area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.943854 FAM86C2P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2546 GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20512 Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178714_6_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 496100542_PCx_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.18544 Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.0386 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03392 medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09055 GSE180185_7_v_5_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.13101 GSE128333_2_v_5_tcf4_human RummaGEO Gene Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.965864 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921831 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40661 Benign vascular tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 BEAS-2B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.507 GTEX-XYKS-0526-SM-4BRW2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.853383 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45772 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16555 FGFR3_KD_GSE41035_77_human_RT112 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sperm principal piece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.401 SFXN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62874 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE264621_1_v_6_secretin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XLM4-0011-R4B-SM-4AT5C GTEx Tissue Sample Gene Expression Profiles 1.0 0.886804 MEF2A_01_265 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.13903 GSE202603_3_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.05621 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SKNDZ CCLE Cell Line Gene CNV Profiles -1.0 -1.40004 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23038 JURKAT DepMap CRISPR Gene Dependency 1.0 2.98236 GSE197850_4_v_0_glucagon_human RummaGEO Drug Perturbation Signatures 1.0 null CTF1 MotifMap Predicted Transcription Factor Targets 1.0 null TE-6 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7412 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943078 GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RE-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.260538 GSE208096_1_v_0_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SW1710 CCLE Cell Line Gene CNV Profiles -1.0 -1.39522 SKES1 CCLE Cell Line Gene Expression Profiles 1.0 1.45217 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null GSE121809_1_v_0_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100622_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.62551 CREB3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20657 TC32 CCLE Cell Line Gene Expression Profiles 1.0 1.791 Rectum adenocarcinoma_READ_TCGA-EI-6506-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.7452 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0391 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27826 RTL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49487 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050281 adrenal gland GTEx Tissue Gene Expression Profiles -1.0 -0.889398 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17547 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.8757 GTEX-WL46-0011-R6A-SM-3LK6X GTEx Tissue Sample Gene Expression Profiles 1.0 0.945529 GTEX-Q2AG-0011-R4A-SM-2HMKA GTEx Tissue Sample Gene Expression Profiles 1.0 0.919016 Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883828 L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.38713 mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.12571 Mood disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.733 TIA1_KO_GSE54418_261_mouse_midbrain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.60749 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847102 LS123 DepMap CRISPR Gene Dependency 1.0 3.37771 Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.95934 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57789 CHP126 CCLE Cell Line Gene Expression Profiles -1.0 -1.53631 HOXA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74393 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.9136 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.17756 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZSWIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41537 dorsolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34207 Extrinsic asthma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 CTCF ENCODE Transcription Factor Targets 1.0 null GSE164494_0_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE157555,GSE157556_0_v_6_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.22091 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39186 FAM181 InterPro Predicted Protein Domain Annotations 1.0 null GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles 1.0 0.853435 primary auditory cortex (core)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.831071 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.860438 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18822 hsa-miR-4708-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 mRNA_OTX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null icSARA deltaORF6_54Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.86526 Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X261-0011-R10B-SM-4E3JT GTEx Tissue Sample Gene Expression Profiles 1.0 1.24859 GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles 1.0 1.10677 GSE173262_2_v_0_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28335 posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.941059 liver GTEx Tissue Gene Expression Profiles -1.0 -1.49191 COLO680N CCLE Cell Line Gene Expression Profiles -1.0 -1.67947 outer CP in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.907455 GSE195559_8_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null OVCAR5 CCLE Cell Line Gene CNV Profiles -1.0 -1.36606 hsa-miR-4736 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.864603 MFE280 CCLE Cell Line Gene Expression Profiles 1.0 1.842 PMC10863267-12864_2024_10083_MOESM1_ESM.pdf-228-LHX2_LHX2 Rummagene Transcription Factor Associations 2026 1.0 null PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2 Rummagene Transcription Factor Associations 2026 1.0 null primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62519 amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.873209 posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46171 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 0.871353 VMRCLCD DepMap CRISPR Gene Dependency 1.0 4.15778 SLVL COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.992239 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.961327 Female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 organelle LOCATE Predicted Protein Localization Annotations 1.0 null SP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.827665 Temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Lyf-1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE143316_0_v_6_somatostatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE195559_0_v_1_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE178714_5_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5357 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.4104 A-172 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.5 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.968281 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.033 GTEX-RVPU-0011-R3A-SM-2XCAE GTEx Tissue Sample Gene Expression Profiles 1.0 0.990684 testis HPA Tissue Protein Expression Profiles 1.0 1.00156 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2932 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -1.6804 hippocampus (hippocampal formation)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.84621 SUDHL10 CCLE Cell Line Gene Expression Profiles 1.0 1.36863 P3HR1 CCLE Cell Line Gene Expression Profiles 1.0 1.50084 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056545 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9443 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27114 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.943839 TGW COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 0.980486 M059J COSMIC Cell Line Gene Mutation Profiles 1.0 null Male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.086 GSE129389_0_v_5_tropifexor_mouse RummaGEO Drug Perturbation Signatures 1.0 null UMRC2 CCLE Cell Line Gene CNV Profiles -1.0 -2.04602 Perturb_13790_KO_Zeb2_SRP066910 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 496100634_HIP_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.06034 Brain Lower Grade Glioma_LGG_TCGA-CS-5397-01A-01R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202603_1_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.994118 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.94035 HS675T CCLE Cell Line Gene Expression Profiles -1.0 -1.47154 PKNOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01818 GTEX-X585-0011-R2B-SM-46MVF GTEx Tissue Sample Gene Expression Profiles 1.0 1.1478 KASUMI2 CCLE Cell Line Gene CNV Profiles -1.0 -1.53066 HCC2935 CCLE Cell Line Gene CNV Profiles 1.0 1.402 H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2056 MZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.893402 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63T-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5205 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882697 hsa-miR-520d-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 1.53073 ARH77 DepMap CRISPR Gene Dependency 1.0 5.74713 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10212 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16185 496100327_PCx_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.19699 Atrial appendage TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.636 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050342 GTEX-X4EP-0011-R2B-SM-3P625 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27553 Cul2-RING ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.665 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882697 NCIH3255 CCLE Cell Line Gene CNV Profiles 1.0 1.60518 SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11491 GTEX-T6MN-0011-R4A-SM-32QPG GTEx Tissue Sample Gene Expression Profiles 1.0 0.872702 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 STAT3 ChEA Transcription Factor Targets 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12219 GTEX-RVPU-0011-R10A-SM-2XCAH GTEx Tissue Sample Gene Expression Profiles 1.0 1.04945 Colonic benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.176 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29219 VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04394 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85434 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18632 NCI-H727 COSMIC Cell Line Gene Mutation Profiles 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050342 MCC13 DepMap CRISPR Gene Dependency 1.0 3.97387 ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1924 GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 0.896396 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69011 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.70823 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882697 GSE178113,GSE178116_0_v_1_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null PACADD161 DepMap CRISPR Gene Dependency 1.0 3.02077 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung adenocarcinoma_LUAD_TCGA-80-5607-01A-31R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-0011-R3B-SM-4AT6E GTEx Tissue Sample Gene Expression Profiles 1.0 0.963404 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.934189 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40977 GTEX-T2IS-0011-R6A-SM-32QP2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.832601 Buccal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.067 Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0011-R8A-SM-4B65J GTEx Tissue Sample Gene Expression Profiles 1.0 0.865807 C8166 DepMap CRISPR Gene Dependency 1.0 2.33395 Endometrial stromal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.025 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NPJ7-0011-R5a-SM-33HBK GTEx Tissue Sample Gene Expression Profiles 1.0 0.883132 DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 EW1 DepMap CRISPR Gene Dependency 1.0 2.47154 Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DPEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54616 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.52947 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sirolimus_homo sapiens_gpl2895_gse16944 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 In situ melanoma of skin_Epidermis_GSE4587 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.24126 TEAD-YAP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.946 GTEX-QVJO-0011-R8A-SM-447C7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.981379 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5064 EB2 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1359 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944335 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.881487 EP300 ENCODE Transcription Factor Targets 1.0 null granulocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.334865 GSE214382,GSE214383_1_v_2_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.862538 GSE153836_14_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 0.891172 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null brain HPA Tissue Gene Expression Profiles 1.0 1.41691 Bronchial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.269 GSE200352_11_v_6_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null amygdaloid complex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.06942 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03168 Chronic asthma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6354 KURAMOCHI CCLE Cell Line Gene Expression Profiles 1.0 1.61206 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18609 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978433 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30491 GSE197850_4_v_2_glucagon_human RummaGEO Drug Perturbation Signatures 1.0 null GSE129389_0_v_6_tropifexor_mouse RummaGEO Drug Perturbation Signatures 1.0 null paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86218 caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25347 AP3S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87622 NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.869438 GSE142684_0_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.52539 icSARS CoV_54Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.48946 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.58344 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.5905 external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46039 lateral hypothalamic area, mammillary region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.931613 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.57713 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8257-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.869438 PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2226 GTEX-WHSE-0011-R1A-SM-3P5ZK GTEx Tissue Sample Gene Expression Profiles 1.0 0.921127 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.82463 GSE206400_3_v_4_nusinersen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178714_5_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13226 Perturb_8476_KO_CTNNB1_SRP137216 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CD-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.59125 JUN JASPAR Predicted Transcription Factor Targets 1.0 null TRMT9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78002 Ebf4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 44.3964 GTEX-RVPU-0011-R1A-SM-2XCAI GTEx Tissue Sample Gene Expression Profiles 1.0 0.940616 Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Duodenum Mucosa Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.67292 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null HT3 DepMap CRISPR Gene Dependency 1.0 2.04687 RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH446 DepMap CRISPR Gene Dependency 1.0 2.91008 Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 57.3357 ChIP_RCOR3_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2587 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null TM31 CCLE Cell Line Gene Expression Profiles -1.0 -2.10662 GSE247084,GSE247087_0_v_1_cdyl_human RummaGEO Gene Perturbation Signatures -1.0 null NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61617 outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60746 hsa-miR-4290 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 HEC59 DepMap CRISPR Gene Dependency 1.0 2.18521 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.49364 GTEX-QCQG-0326-SM-2I3ES GTEx Tissue Sample Gene Expression Profiles 1.0 0.841537 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GN-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EI-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE120200,GSE127269_1_v_2_asxl1_human RummaGEO Gene Perturbation Signatures -1.0 null TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1256 amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08413 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04981 Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 ESR1_KD_GDS4061_453_human_MCF7 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null THY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06086 WDTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52389 hippocampus (hippocampal formation)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35655 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE70499_5_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-P44H-0011-R1A-SM-3NM8J GTEx Tissue Sample Gene Expression Profiles 1.0 1.09264 peripheral portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33476 amygdalohippocampal transition zone, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27573 SNU1079 CCLE Cell Line Gene CNV Profiles 1.0 1.48942 Depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.733 NALM16 DepMap CRISPR Gene Dependency 1.0 4.43938 SLC44A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90578 GTEX-NL4W-0011-R2a-SM-2I5GV GTEx Tissue Sample Gene Expression Profiles 1.0 0.956655 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.48768 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5539 mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.75235 NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE112714_2_v_0_ctnnb1_human RummaGEO Gene Perturbation Signatures -1.0 null primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.92223 hsa-miR-3133 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 GSE210580_3_v_6_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.830476 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62706 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957688 GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 0.876506 SP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.62891 Perturb_9447_KD_ESR2_SRP275562 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.58677 basolateral nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.952366 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.51671 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_4143_KO_Bcl11a_SRP334609 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.92305 Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1464 GSE114992,GSE114993_0_v_3_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE245778_1_v_0_runx1_human RummaGEO Gene Perturbation Signatures -1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.894194 GTEX-X585-0011-R6A-SM-46MVJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.872979 PECAPJ34CLONEC12 CCLE Cell Line Gene CNV Profiles 1.0 1.37688 IRF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22513 496100426_PCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.69667 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62837 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8 Rummagene Transcription Factor Associations 2026 1.0 null EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JC-0011-R4A-SM-32PLT GTEx Tissue Sample Gene Expression Profiles 1.0 0.913079 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE229698_1_v_2_traf7_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X261-0011-R8A-SM-4E3I5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.916825 ZBTB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33342 PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.61214 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.68624 Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE153836_14_v_5_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.856976 OVMANA CCLE Cell Line Gene CNV Profiles -1.0 -1.64346 GSE114992,GSE114993_7_v_11_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_5_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null NCIH28 CCLE Cell Line Gene CNV Profiles -1.0 -1.40565 amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.71484 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30102 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18651 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59578 Deuterosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.955 SCC-9 COSMIC Cell Line Gene Mutation Profiles 1.0 null Ikzf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.5664 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26405 GTEX-NL4W-0011-R8a-SM-2I3G4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.84518