association dataset threshold value standardized value 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.836557 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.320227 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK1-19687146-Hela cells-human ChEA Transcription Factor Binding Site Profiles 1.0 null internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978247 MOLM16 CCLE Cell Line Gene CNV Profiles -1.0 -1.42414 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51091 Brain Lower Grade Glioma_LGG_TCGA-QH-A6X3-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.08055 COLO668 CCLE Cell Line Gene CNV Profiles -1.0 -1.47181 EFE184 CCLE Cell Line Gene Expression Profiles 1.0 1.44199 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 EC-GI-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null 18801183-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null KYSE220 DepMap CRISPR Gene Dependency 1.0 2.96975 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.131199 SNU1 CCLE Cell Line Gene Expression Profiles 1.0 1.57591 Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPMI7951 DepMap CRISPR Gene Dependency 1.0 2.71438 CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-320d TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 DB CCLE Cell Line Gene CNV Profiles -1.0 -1.37579 RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PATU8902 DepMap CRISPR Gene Dependency 1.0 2.19888 RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDK7_knockdown_138_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.8005 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.868735 Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null M059K DepMap CRISPR Gene Dependency 1.0 2.36873 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 hsa-miR-4486 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCAR4 CCLE Cell Line Gene CNV Profiles 1.0 1.4934 OAW42 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06968 EZH2 ENCODE Transcription Factor Targets 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NOZ DepMap CRISPR Gene Dependency 1.0 3.9121 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.6903 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UMUC7 DepMap CRISPR Gene Dependency 1.0 2.04266 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56987 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68697 MDAMB415 CCLE Cell Line Gene CNV Profiles 1.0 1.44055 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null LOUCY CCLE Cell Line Gene CNV Profiles -1.0 -2.49254 ERRalpha_Deficiency_GDS2727_646_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SREBF2 JASPAR Predicted Transcription Factor Targets 1.0 null OCILY10 CCLE Cell Line Gene Expression Profiles 1.0 1.6753 RT11284 CCLE Cell Line Gene Expression Profiles -1.0 -1.51929 H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25949 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16984 male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null CAL78 CCLE Cell Line Gene Expression Profiles -1.0 -1.57504 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX3 ENCODE Transcription Factor Targets 1.0 null nucleoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.222436 MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5935-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS153 CCLE Cell Line Gene CNV Profiles -1.0 -2.02573 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17707 HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838565 C84 DepMap CRISPR Gene Dependency 1.0 4.75538 male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BATF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72385 PBX3 ENCODE Transcription Factor Targets 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15418 Prostate adenocarcinoma_PRAD_TCGA-VN-A88P-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39551 CLPP_KO_GSE40207_388_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null U87MG DepMap CRISPR Gene Dependency 1.0 2.22015 H3K36me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null LB647-SCLC COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH1355 DepMap CRISPR Gene Dependency 1.0 3.07076 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043272 SQ1 CCLE Cell Line Gene Expression Profiles 1.0 2.25041 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-34-8454-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 HDAC2 ENCODE Transcription Factor Targets 1.0 null SW 982 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27738 NCIH1581 CCLE Cell Line Gene CNV Profiles -1.0 -1.61875 CLPP_KO_GDS4791_104_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null PCDH12_Deficiency_GDS3415_577_mouse_Embryonic placentas (12.5 day) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.33465 OAW28 CCLE Cell Line Gene Expression Profiles -1.0 -2.59041 posteroventral (inferior) parietal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.56977 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.910124 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNUC2A CCLE Cell Line Gene Expression Profiles -1.0 -1.81106 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of ion homeostasis GWASdb SNP-Phenotype Associations 1.0 0.152643 iron GAD Gene-Disease Associations 1.0 null SNU1272 CCLE Cell Line Gene CNV Profiles 1.0 1.39681 Perturb_17423_KO_Cic_SRP126501 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.79747 dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.930957 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1876 CCLE Cell Line Gene Expression Profiles -1.0 -1.60633 CAL851 CCLE Cell Line Gene Expression Profiles 1.0 1.42076 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCIH209 CCLE Cell Line Gene Expression Profiles -1.0 -1.93126 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.856388 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KP-N-RT-BM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6836-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H357 DepMap CRISPR Gene Dependency 1.0 2.28342 BICR 10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87488 Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10265 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.06061 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16025 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45404 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MALME3M CCLE Cell Line Gene CNV Profiles -1.0 -1.73027 Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mineral metabolism disease GWASdb SNP-Disease Associations 1.0 0.331143 OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831313 primary motor cortex (area M1, area 4)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.944956 GATA3 ENCODE Transcription Factor Targets 1.0 null STAT1 JASPAR Predicted Transcription Factor Targets 1.0 null CAL-51 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20534 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11798 AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08434 JUND ENCODE Transcription Factor Targets 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3937 19658189-TableS3 GeneSigDB Published Gene Signatures 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33681 inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09901 Lung adenocarcinoma_LUAD_TCGA-05-4424-01A-22R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-11A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.948475 primary motor cortex (area M1, area 4)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.93951 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null NUGC4 CCLE Cell Line Gene Expression Profiles 1.0 2.90559 testis HPA Tissue Protein Expression Profiles 1.0 2.04572 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20617 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30494 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.983514 primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.880603 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW620 CCLE Cell Line Gene Expression Profiles -1.0 -1.90124 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-11A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB69 DepMap CRISPR Gene Dependency 1.0 2.5856 female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.984241 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27782 primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14386 hsa-miR-320c TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCA420 DepMap CRISPR Gene Dependency 1.0 2.38587 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87488 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880458 hsa-miR-3545-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01868 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25014 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.919439 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4693-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042791 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.791149 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77183 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.92397 NCIH727 DepMap CRISPR Gene Dependency 1.0 3.50795 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56893 H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K36me3_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null HCC2185 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.89773 COLO-668 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96288 Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21929 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29M-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2877-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2342 CCLE Cell Line Gene CNV Profiles -1.0 -2.20748 H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61595 MDA-MB-415 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.16557 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A8BP-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1105 CCLE Cell Line Gene CNV Profiles -1.0 -1.60989 Caudatenucleus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.26544 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LP1 DepMap CRISPR Gene Dependency 1.0 2.1098 NCIH211 CCLE Cell Line Gene CNV Profiles -1.0 -1.62668 Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CL34 CCLE Cell Line Gene Expression Profiles -1.0 -2.17699 SET2 CCLE Cell Line Gene CNV Profiles -1.0 -2.03311 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929827 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04481 facioscapulohumeral muscular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.32803 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.04343 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EA-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null A-CA-04-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.21105 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.910124 cell part GO Cellular Component Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-92-8064-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DBTRG05MG DepMap CRISPR Gene Dependency 1.0 2.20151 Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.86943 KYSE30 CCLE Cell Line Gene Expression Profiles 1.0 1.35206 Acute Myeloid Leukemia_LAML_TCGA-AB-2823-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.57978 NCIH226 DepMap CRISPR Gene Dependency 1.0 6.17932 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.15849 nucleus GO Cellular Component Annotations 2023 1.0 null SNU182 DepMap CRISPR Gene Dependency 1.0 2.13403 HOP-92 COSMIC Cell Line Gene Mutation Profiles 1.0 null Hypb_Deficiency_GDS3641_523_mouse_Yolk sac from E10.5 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045261 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040674 NR2F2_01_89 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.5967 H2AFZ ENCODE Transcription Factor Targets 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22316 FXR MotifMap Predicted Transcription Factor Targets 1.0 null liver GTEx Tissue Gene Expression Profiles -1.0 -0.841237 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06298 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null orbital frontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.918335 Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.868423 iron metabolism disease GWASdb SNP-Disease Associations 1.0 0.526189 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75361 NCIH2110 DepMap CRISPR Gene Dependency 1.0 4.40556 NH6 CCLE Cell Line Gene Expression Profiles 1.0 1.58706 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78766 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null 697 CCLE Cell Line Gene Expression Profiles 1.0 1.90029 Acute Myeloid Leukemia_LAML_TCGA-AB-2881-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2429 DepMap CRISPR Gene Dependency 1.0 2.14151 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07078 JHUEM3 CCLE Cell Line Gene Expression Profiles -1.0 -1.50817 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51091 SW872 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 hsa-miR-4653-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CORL51 CCLE Cell Line Gene CNV Profiles -1.0 -1.77508 CBFB_01_43 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.28293 Leukemialymphoblastic(MOLT-4) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.925472 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_3277_KD_RORA_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NCIH211 CCLE Cell Line Gene Expression Profiles -1.0 -1.86499 CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TLE2_02_53 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.16993 PL-21 COSMIC Cell Line Gene Mutation Profiles 1.0 null PRDM1 JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8191-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.910124 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.31801 KPNYN DepMap CRISPR Gene Dependency 1.0 2.02318 RC-K8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53738 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.71466 MYC ChEA Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.835192 BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22509 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927531 NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838565 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045701 SNU410 CCLE Cell Line Gene CNV Profiles 1.0 2.28068 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18691 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GDS4791_537_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Sarcoma_SARC_TCGA-DX-A8BS-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3389_KO_Tcf7_SRP217200 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 14.453 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AC-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4701-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACCMESO1 CCLE Cell Line Gene CNV Profiles 1.0 1.5672 KHM1B CCLE Cell Line Gene Expression Profiles 1.0 1.49117 NFIC ENCODE Transcription Factor Targets 1.0 null gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27738 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028101 Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PEO4 DepMap CRISPR Gene Dependency 1.0 2.45919 NCIH1435 CCLE Cell Line Gene CNV Profiles -1.0 -1.53427 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904191 NCIH1694 DepMap CRISPR Gene Dependency 1.0 3.5526 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null E2A MotifMap Predicted Transcription Factor Targets 1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.9587 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HS729 DepMap CRISPR Gene Dependency 1.0 2.12424 VMRCLCD DepMap CRISPR Gene Dependency 1.0 3.03246 CFPAC1 CCLE Cell Line Gene Expression Profiles 1.0 1.71165 SKMES1 DepMap CRISPR Gene Dependency 1.0 3.91489 MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969879 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27225 BCP1 CCLE Cell Line Gene Expression Profiles 1.0 1.53151 hsa-miR-4795-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4429 TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSC4 DepMap CRISPR Gene Dependency 1.0 3.32565 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.58943 ELK1 ENCODE Transcription Factor Targets 1.0 null SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.42055 SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.0743 hsa-miR-4418 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.18318 Brain Lower Grade Glioma_LGG_TCGA-DU-6399-01A-12R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LPS6 DepMap CRISPR Gene Dependency 1.0 4.25011 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12822 PDK1_knockout_80_GSE26290 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.076819 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7834-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11082 Oligospermia CTD Gene-Disease Associations 1.0 1.02671 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null JHOS4 CCLE Cell Line Gene CNV Profiles 1.0 1.81167 COV362 CCLE Cell Line Gene CNV Profiles 1.0 1.72162 hsa-miR-509-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.825753 SNU-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87506 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5KY-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02189 Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05523 BHY CCLE Cell Line Gene Expression Profiles -1.0 -2.16619 CHP134 DepMap CRISPR Gene Dependency 1.0 4.00616 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15418 Lung adenocarcinoma_LUAD_TCGA-86-8076-01A-31R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050238 ribonucleoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.050038 H3K27me3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BATF ENCODE Transcription Factor Targets 1.0 null HCC-78 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary motor cortex (area M1, area 4)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27554 KARPAS-231 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.986487 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SK-MEL-24 COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU5 CCLE Cell Line Gene CNV Profiles 1.0 1.69454 NCIN87 CCLE Cell Line Gene Expression Profiles -1.0 -1.71416 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060157 WPE1NA22 DepMap CRISPR Gene Dependency 1.0 2.08099 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17414 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GU-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.235457 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16847 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F4-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.875076 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893508 769P DepMap CRISPR Gene Dependency 1.0 3.12108 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46208 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8312-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.058136 RUNX2 JASPAR Predicted Transcription Factor Targets 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.048109 Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01528 NCIH1836 CCLE Cell Line Gene Expression Profiles -1.0 -1.54691 UBB_KO_GDS3906_491_mouse_Testis - 7 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ES-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO741 CCLE Cell Line Gene CNV Profiles -1.0 -1.63781 Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880458 COLO775 CCLE Cell Line Gene Expression Profiles 1.0 1.85063 GATA3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23306 STAT1 ChEA Transcription Factor Targets 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_12Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.21903 primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00869 posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01246 GATA3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87488 BL3513 (KDM4A) NURSA Protein Complexes 1.0 null cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.957372 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041994 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null TUHR14TKB CCLE Cell Line Gene CNV Profiles 1.0 2.05726 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12074 abnormality of cation homeostasis GWASdb SNP-Phenotype Associations 1.0 0.152643 TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.67353 UOK101 DepMap CRISPR Gene Dependency 1.0 2.48671 H3K9me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.337975 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null RUNX1 ChEA Transcription Factor Targets 1.0 null TBL1XR1 ENCODE Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-F5-6811-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17052 TE-8 COSMIC Cell Line Gene Mutation Profiles 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.33914 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKN DepMap CRISPR Gene Dependency 1.0 3.99177 Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.922305 Lung adenocarcinoma_LUAD_TCGA-55-7576-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IMR32 DepMap CRISPR Gene Dependency 1.0 2.51742 Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.51911 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45313 thyroid GTEx Tissue Gene Expression Profiles -1.0 -1.11463 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.11013 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10265 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46429 Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3613-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34069 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1648 CCLE Cell Line Gene CNV Profiles 1.0 1.43237 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB7_01_169 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.88876 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5088-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.055704 nuclear body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.444085 HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.823435 Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60137 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042427 CGTHW1 CCLE Cell Line Gene CNV Profiles 1.0 1.73812 HS939-T COSMIC Cell Line Gene Mutation Profiles 1.0 null ELK1 ChEA Transcription Factor Targets 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null SNU349 CCLE Cell Line Gene CNV Profiles 1.0 2.87286 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.884022 Sarcoma_SARC_TCGA-IS-A3K7-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1544 DepMap CRISPR Gene Dependency 1.0 2.11263 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IC-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16984 CHK1_KD_GSE54268_666_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.66813 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null SYO1 DepMap CRISPR Gene Dependency 1.0 6.12988 Sarcoma_SARC_TCGA-DX-A6B8-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUPM2 DepMap CRISPR Gene Dependency 1.0 4.69963 Prostate adenocarcinoma_PRAD_TCGA-CH-5765-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.88214 gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 hsa-miR-320a TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3585 MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11419 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24D-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SFTPC_KO_GSE35989_48_mouse_lung (type II cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BL70 DepMap CRISPR Gene Dependency 1.0 2.5605 SFTPC_KO_GDS4876_476_mouse_Lung Type II cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.92904 Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.15899 Lung adenocarcinoma_LUAD_TCGA-05-4415-01A-22R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAOV4 DepMap CRISPR Gene Dependency 1.0 4.09028 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.35703 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2011_KO_Cd40lg_ERP130522 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Lung adenocarcinoma_LUAD_TCGA-97-A4M5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984733 SKBR3 DepMap CRISPR Gene Dependency 1.0 3.97661 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO680N DepMap CRISPR Gene Dependency 1.0 2.37549 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042532 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CORL311 CCLE Cell Line Gene CNV Profiles -1.0 -1.35188 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TIG3TD CCLE Cell Line Gene Expression Profiles -1.0 -1.46014 Brain Lower Grade Glioma_LGG_TCGA-DU-6394-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12267 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15418 JIMT1 CCLE Cell Line Gene CNV Profiles 1.0 1.69454 GCT CCLE Cell Line Gene CNV Profiles 1.0 1.54232 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KRAP_Deficiency_GDS3528_564_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.92904 Get-1_Deficiency_GDS2629_161_mouse_embryonic skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null spliceosomal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.560943 endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 KMS12BM CCLE Cell Line Gene CNV Profiles -1.0 -1.39707 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08434 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27871 MYC-20876797-MEDULLOBLASTOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.336876 NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-8200-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T84 CCLE Cell Line Gene Expression Profiles 1.0 2.01632 neuromuscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.478668 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27738 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAP2K1_knockdown_134_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.50763 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61666 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JVE015 DepMap CRISPR Gene Dependency 1.0 2.64455 HLE COSMIC Cell Line Gene Mutation Profiles 1.0 null BEN CCLE Cell Line Gene Expression Profiles -1.0 -1.60817 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06349 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_3276_KD_RORA_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.53886 OPM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.33945 RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.993553 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050238 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047523 muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.337242 Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5849-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.839653 Iron dbGAP Gene-Trait Associations 1.0 0.008498 AM38 CCLE Cell Line Gene CNV Profiles -1.0 -1.74186 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAL-12T COSMIC Cell Line Gene Mutation Profiles 1.0 null RALDH2_KO_GSE43578_6_mouse_head (rostral or posterior) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16847 Brain Lower Grade Glioma_LGG_TCGA-E1-5305-01A-01R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.846474 Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1648 COSMIC Cell Line Gene Mutation Profiles 1.0 null female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PBX3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040416 EBF1 ENCODE Transcription Factor Targets 1.0 null CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.70315 A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.5239 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978247 neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.335778 LS1034 DepMap CRISPR Gene Dependency 1.0 2.44541 NCIH1666 DepMap CRISPR Gene Dependency 1.0 2.53695 MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-320b TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 GCT CCLE Cell Line Gene Expression Profiles -1.0 -1.53256 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30451 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null T98G COSMIC Cell Line Gene Mutation Profiles 1.0 null G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904191 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.32044 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.20615 NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null MFE319 CCLE Cell Line Gene Expression Profiles 1.0 2.11 BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7033 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GSE40207_392_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hippocampus (hippocampal formation)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.23942 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH1963 CCLE Cell Line Gene CNV Profiles -1.0 -2.29081 NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.845384 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC3153 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.41726 TP53 JASPAR Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PC3 CCLE Cell Line Gene CNV Profiles 1.0 2.4377 LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QB-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null SUDHL4 DepMap CRISPR Gene Dependency 1.0 8.09655 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.840896 BL70 CCLE Cell Line Gene Expression Profiles 1.0 1.81106 COLO320 DepMap CRISPR Gene Dependency 1.0 2.42429 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46429 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.078234 HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.52496 BL5433 (ERCC6) NURSA Protein Complexes 1.0 null H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 MFE296 CCLE Cell Line Gene Expression Profiles -1.0 -2.53111 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SU8686 COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null striatum_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.89458 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC-08-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null STAT1-20625510-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.87828 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A427 COSMIC Cell Line Gene Mutation Profiles 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15418 Lung adenocarcinoma_LUAD_TCGA-55-8091-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.827048 HCC38 CCLE Cell Line Gene Expression Profiles -1.0 -3.58408 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02707 CESS COSMIC Cell Line Gene Mutation Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978247 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33681 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.960475 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050186 GATA-1_KD_GDS1245_81_mouse_megakaryocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SKMEL3 CCLE Cell Line Gene CNV Profiles 1.0 1.80383 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00804 BICR56 CCLE Cell Line Gene Expression Profiles 1.0 2.45044 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969879 AU565 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.00169 ST486 CCLE Cell Line Gene Expression Profiles 1.0 1.53844 SR-786 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17414 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02707 skeletal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.451428 CAKI2 DepMap CRISPR Gene Dependency 1.0 2.43129 NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34931 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DU4475 CCLE Cell Line Gene Expression Profiles 1.0 2.72055 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VK-01A-21R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.910124 EP300_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Protein of unknown function DUF3699 InterPro Predicted Protein Domain Annotations 1.0 null VMRCLCP CCLE Cell Line Gene CNV Profiles -1.0 -1.41182 nucleolus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.345692 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS34 CCLE Cell Line Gene CNV Profiles -1.0 -1.3324 Lassa Fever Virus_8hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.43414 253J DepMap CRISPR Gene Dependency 1.0 5.67923 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM149PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.583516 C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null KMRC2 CCLE Cell Line Gene CNV Profiles 1.0 1.57233 59M CCLE Cell Line Gene Expression Profiles 1.0 1.54411 SW837 CCLE Cell Line Gene CNV Profiles 1.0 1.3617 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.79607 KNS62 CCLE Cell Line Gene Expression Profiles 1.0 1.50543 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DU4475 DepMap CRISPR Gene Dependency 1.0 3.63787 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.28581 all GWASdb SNP-Phenotype Associations 1.0 0.028084 EMC-BAC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.24557 ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042625 primary motor cortex (area M1, area 4)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09341 CORL88 CCLE Cell Line Gene CNV Profiles -1.0 -1.34286 KG1 CCLE Cell Line Gene CNV Profiles -1.0 -3.19745 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38785 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.827136 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.17481 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null nucleus GO Cellular Component Annotations 2015 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75361 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.31945 CTNNB1_OE_GDS4449_352_mouse_Embryonic kidney from E12.5 embryos (-catGOF-UB mutant) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.12992 WAOSEL DepMap CRISPR Gene Dependency 1.0 7.98083 19658189-TableS5 GeneSigDB Published Gene Signatures 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZL-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46292 Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T-T COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.79058 atrophic muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.580828 skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052647 ICC2 DepMap CRISPR Gene Dependency 1.0 2.19982 A673 CCLE Cell Line Gene CNV Profiles -1.0 -1.79679 NCIH2081 CCLE Cell Line Gene Expression Profiles -1.0 -2.31165 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6E9-06A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.79724 Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TSC1_Deficiency_GDS4572_347_mouse_Naive CD8 T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HCC1171 CCLE Cell Line Gene CNV Profiles 1.0 1.50751 TSC1_Deficiency_GDS4572_346_mouse_Naive CD4 T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCIP5X DepMap CRISPR Gene Dependency 1.0 2.73752 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929827 COLO684 CCLE Cell Line Gene Expression Profiles 1.0 1.63123 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3361_OE_Bach2_SRP267100 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null C32 COSMIC Cell Line Gene Mutation Profiles 1.0 null OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56893 Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H508 COSMIC Cell Line Gene Mutation Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.13064 HCV_8week+IFN-a_None_GSE37715 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.93559 HUH1 CCLE Cell Line Gene Expression Profiles 1.0 1.3874 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null IPC-298 COSMIC Cell Line Gene Mutation Profiles 1.0 null MCF 10A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39551 Lung adenocarcinoma_LUAD_TCGA-MP-A4TI-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KG1C CCLE Cell Line Gene CNV Profiles 1.0 1.47177 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30068 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.93523 TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung GTEx Tissue Gene Expression Profiles -1.0 -1.45869 EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of iron homeostasis GWASdb SNP-Phenotype Associations 1.0 0.448846 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.98647 CLPP_KO_GSE40207_378_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SC-5278 (CHEK2) NURSA Protein Complexes 1.0 null SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null DMS79 CCLE Cell Line Gene CNV Profiles -1.0 -1.46506 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54117 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.855306 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.897981 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.861906 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02629 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R9-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX1 ChEA Transcription Factor Targets 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.023706 striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.87877 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-3008-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 MDA-MB-468 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH2126 CCLE Cell Line Gene Expression Profiles -1.0 -1.65311 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.01327 ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00951 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XC-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of transition element cation homeostasis GWASdb SNP-Phenotype Associations 1.0 0.224479 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19872 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02629 MDAMB436 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.80509 HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.719 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.828848 OccipitalLobe BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.80387 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 HS936T CCLE Cell Line Gene Expression Profiles 1.0 1.35334 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleoplasm part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.246407 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.93951 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PGA1 DepMap CRISPR Gene Dependency 1.0 2.89473 H3K27me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40863 SNUC4 DepMap CRISPR Gene Dependency 1.0 2.33048 breast GTEx Tissue Gene Expression Profiles 1.0 1.98311 hsa-miR-4292 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 CLPP_KO_GDS4791_374_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-320e TargetScan Predicted Conserved microRNA Targets 1.0 0.436802 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19W-06A-41R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.839653 CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4599-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45682 SKMES1 CCLE Cell Line Gene CNV Profiles 1.0 1.82313 Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-509-3-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 IM-95 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAP4K5_knockdown_199_GSE61497 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.83872 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.990988 cajal body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.703067 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978247 H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AR ChEA Transcription Factor Targets 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042207 TE15 CCLE Cell Line Gene Expression Profiles 1.0 1.65083 primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.896695 Hepatic Cirrhosis_Liver_GSE6764 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.28928 muscular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.580828 H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53333 CAL120 CCLE Cell Line Gene Expression Profiles -1.0 -2.30628 H3K27me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cebpa_22442349_pbmc_lof_human_gpl570_gds4407 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.02237 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18116 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838565 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838565 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978247