association	dataset	threshold value	standardized value
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2659
NUMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33373
GDPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6012
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81121
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79216
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IDH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12572
ULK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75557
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65867
FOXO3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10733
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96336
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5561
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98147
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15643
OXCT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67987
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13949
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.98642
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2366
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12984
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6849
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4114
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2672
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53959
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
CYLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98191
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35034
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87654
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13373
ARL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05959
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1217
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77541
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87603
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55022
PHF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59088
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67838
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.636
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.1034
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMKK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2776
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25653
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1024
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42607
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6489
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40921
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9899
GSE226285_2_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3319
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78723
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76581
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84002
MRPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72006
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24709
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36211
CFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35467
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9475
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0492
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08363
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50772
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21487
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6716
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9168
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23319
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4675
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1285
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0363
FXYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27057
CRTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10523
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62033
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30347
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6591
RTL8C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83512
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2602
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01079
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20552
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25223
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94761
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41517
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4457
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31316
TOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11769
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49345
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2156
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1585
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.0895
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.281
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05983
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51827
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65925
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
DNAJC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90933
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2478
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8238
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8614
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2832
SAMD14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22437
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPZOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45379
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3898
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
GSE226285_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGAP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57361
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2159
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04181
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26761
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.72
MMP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1942
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FZD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80795
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3814
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
CNTROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44938
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34505
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22128
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9699
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
RAB5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18609
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24113
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01867
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20417
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39461
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05504
ATP5MC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58589
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66048
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41647
UBE2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72376
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5612
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68982
SGF29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3686
496100481_PCx_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80687
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43192
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6075
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80907
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31329
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.184
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.9816
ANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0751
GSE196962_4_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNASEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95822
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88613
AKR7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90455
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70781
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4618
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GRIPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53713
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1218
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.93479
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10153
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5511
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_4_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28256
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19469
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73899
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7945
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11852
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.754
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1264
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39791
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3834
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9006
DDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10087
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.7341
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81368
GSE233679_6_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67471
496100540_TCx_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01259
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05018
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62509
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95299
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71257
KHNYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66276
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64978
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04149
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5432
PCCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44838
RAPGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95265
DNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93324
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13382
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64328
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11753
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06255
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6146
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14907
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78399
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
DLGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43227
ADAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57669
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9389
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89607
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84107
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66764
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4182
496100633_TCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13122
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8248
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM41A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99052
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80085
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27981
SHROOM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14531
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
THUMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46398
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50076
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89137
JPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58441
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83236
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83276
HNF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36517
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3262
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7956
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3737
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81406
ZFPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98728
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48831
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3474
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1677
GPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22996
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1301
STK40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9586
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12696
KLHL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22185
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39635
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
IL17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30043
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
THAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6352
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4204
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2423
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39932
PCGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46966
TMEM9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28271
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31017
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
MIEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89397
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7382
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66778
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17161
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75574
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6543
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.2576
SEBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42249
MAPKAPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26128
C12orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19347
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6722
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63828
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73481
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96271
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8152
EME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06658
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
MRPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98974
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43479
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40986
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3592
HOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21519
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60523
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39965
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6104
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3976
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40706
RHEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06381
496100427_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61222
GCLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49046
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43279
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08281
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3084
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6624
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.326
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77238
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
CFAP126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90657
FADS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72995
TXLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67228
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.953
YTHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42438
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6739
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3788
MAP1LC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4279
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7217
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.477
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09134
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74069