association	dataset	threshold value	standardized value
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13648
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4253
CCAR2_02_146	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.73697
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04302
disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2313
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909695
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.634672
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11783
MDAMB361	DepMap CRISPR Gene Dependency	1.0	6.03413
hsa-miR-3139	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.585
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.878
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0358
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.23238
cell part	GO Cellular Component Annotations 2015	1.0	null
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	1.62044
hsa-miR-542-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Buphthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
Amoeba	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18576
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3751
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72875
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
nuclear chromosome part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.375434
HCC1187	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46811
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05904
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8274
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8032
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
HEC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59748
KYSE520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53775
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9426
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7315
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.826
testis	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40805
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72428
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45736
nuclear part	GO Cellular Component Annotations 2015	1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3955
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884309
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.68317
BFTC-909	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
Tooth germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3928
Leiomyoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL34	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26161
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCIH196	CCLE Cell Line Gene CNV Profiles	1.0	2.1418
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2143
NCI-H3122	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.9644
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045442
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.079269
hsa-miR-4633-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00811
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH747	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54584
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	187.788
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872484
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7390-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1324
nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.364331
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4705
reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.03662
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.33412
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
T47D	CCLE Cell Line Gene CNV Profiles	1.0	1.48362
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
Prostate adenocarcinoma_PRAD_TCGA-EJ-A6RA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216126
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LB647-SCLC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIK3CA_mutant_27_GDS4053	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.74009
X-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965502
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
COLO679	DepMap CRISPR Gene Dependency	1.0	2.38585
DRM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.084
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41076
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65547
leiomyoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.02524
Myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3997
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.97062
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32589
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1990	CCLE Cell Line Gene CNV Profiles	1.0	1.35358
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855712
NCIH1781	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56657
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	1.70772
nucleolus	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4799-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Condensed nuclear chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.21886
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	2.36571
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
spermatid development	GO Biological Process Annotations 2023	1.0	null
J82	DepMap CRISPR Gene Dependency	1.0	2.21549
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.74204
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28695
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	1.0	1.43966
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41076
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7528
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2723
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36855
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965295
Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL11A_01_09	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63355
female reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.1253
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91435
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.709332
stomach	HPA Tissue Protein Expression Profiles	1.0	1.23238
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872451
496100356_TCx_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24792
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.076671
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.3831
COV504	CCLE Cell Line Gene Expression Profiles	-1.0	-2.49225
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60207
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5297
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15127
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
MFM-223	COSMIC Cell Line Gene CNV Profiles	1.0	2.15648
organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.494648
JHH2	DepMap CRISPR Gene Dependency	1.0	2.5792
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.7121
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.74065
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2979
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045292
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040969
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
KM12	CCLE Cell Line Gene Expression Profiles	1.0	2.03044
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11781
Follicular stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
Megalocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77222
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.60529
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.791092
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906697
myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.758673
Prostate adenocarcinoma_PRAD_TCGA-EJ-5516-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT15	CCLE Cell Line Gene Expression Profiles	1.0	1.49711
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75177
uterine benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.1635
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83096
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	2.60032
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1861
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990082
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1788
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.984445
POLR2A	ENCODE Transcription Factor Targets	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914634
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91531
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960439
TE441T	CCLE Cell Line Gene Expression Profiles	1.0	2.65493
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.10566
NCIH1618	CCLE Cell Line Gene CNV Profiles	1.0	1.58636
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Sclerocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71945
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3597
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.2553
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23435
hsa-miR-421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HEL9217	DepMap CRISPR Gene Dependency	1.0	4.95687
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5178-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PATU8988T	DepMap CRISPR Gene Dependency	1.0	5.46532
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38178
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829807
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897056
RMGI	CCLE Cell Line Gene Expression Profiles	1.0	1.38107
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.74452
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25647
Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898946
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81212
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCLAF1_01_214	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.6832
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hematocrit	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17745
KDM1A	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49817
SC-8396 (CCND1)	NURSA Protein Complexes	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.915441
Age at voice drop	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.32
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054071
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.36901
COLO783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7764
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.5132
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360036
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60599
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.84623
Bizarre leiomyoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.628613
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CAPAN2	CCLE Cell Line Gene Expression Profiles	1.0	1.48044
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1198
KINGS1	DepMap CRISPR Gene Dependency	1.0	3.81477
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
SRSF7_02_06	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62803
SKLMS1	CCLE Cell Line Gene Expression Profiles	1.0	2.25278
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5311
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05436
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5053
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051868
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07554
PANC0504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58431
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20435
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988014
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.917
NCI-H2030	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.9644
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35248
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2178
HS766T	CCLE Cell Line Gene Expression Profiles	1.0	1.8649
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4849
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9801
647V	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83111
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
18955564-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49531
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.128
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.507
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215147
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03904
HPAFII	DepMap CRISPR Gene Dependency	1.0	5.70992
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41076
hsa-miR-141	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.329
CAL72	DepMap CRISPR Gene Dependency	1.0	3.68976
IMR32	DepMap CRISPR Gene Dependency	1.0	2.06983
nucleolus	GeneRIF Biological Term Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849049
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71039
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267102
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05351
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.68325
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65234
NCI-H841	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01046
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.085
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	5.79375
PMC9263655-mmc3.xlsx-ZNF436-AS1-Prediction_catRAPID_ZNF436	Rummagene Transcription Factor Associations 2026	1.0	null
Estradiol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.91549
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.3395
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.099
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0083
HCC2157	CCLE Cell Line Gene Expression Profiles	-1.0	-2.81086
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9372
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22742
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.23238
STAT1_01_154	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6119
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83303
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00811
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01046
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829692
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21725
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30764
STAT3	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49909
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82912
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
OSC-19	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.9644
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996774
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00628
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03838
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.867
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
JMJD6	Pathway Commons Protein-Protein Interactions	1.0	null
DDR1_knockdown_169_GSE39207	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63644
Fibroid Tumor	DisGeNET Gene-Disease Associations	1.0	null
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.93326
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09076
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8709
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.126541
KYSE220	DepMap CRISPR Gene Dependency	1.0	6.44926
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898946
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058423
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990703
uterine fibroid	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.16563
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03404
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5631-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.166
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	241.447
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
SKN	DepMap CRISPR Gene Dependency	1.0	11.8497
SETD8	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996384
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.948387
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.65062
JHH6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01135
ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897056
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.23141
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36996
Condensed chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11878
KHM1B	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20964
COLO205	DepMap CRISPR Gene Dependency	1.0	8.31021
SNU182	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67417
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18409
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
binding	GO Molecular Function Annotations 2015	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73112
nucleolus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.369301
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957538
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
H3K9me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24466
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	219.537
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.622
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09288
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.07026
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914634
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9475
A172	CCLE Cell Line Gene CNV Profiles	1.0	1.78395
colon	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MLS syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.902
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92878
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1571
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KE39	DepMap CRISPR Gene Dependency	1.0	2.72699
BJ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8169
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09076
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36258
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892538
located	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43685
Arsenic	CTD Gene-Chemical Interactions	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884309
LOX-1_OE_GDS4262_433_human_HAECT - aortic endothelial cell line - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05103
duodenum	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40045
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00401
HIC1_01_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.08545
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11691
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.30015
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058276
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.9255
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26218
PA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.96919
NCIH1355	DepMap CRISPR Gene Dependency	1.0	3.0238
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-3769-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	GTEx Tissue Gene Expression Profiles	1.0	2.04418
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inguinal canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2753
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2136
NRF1	JASPAR Predicted Transcription Factor Targets	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71623
RNA polymerase II transcription repressor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.067
hsa-miR-4720-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
KPNYN	DepMap CRISPR Gene Dependency	1.0	2.07152
nucleus	GeneRIF Biological Term Annotations	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.758638
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9015
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4245
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4722
NCIH441	CCLE Cell Line Gene Expression Profiles	1.0	1.50568
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1364
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0083
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45229
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855712
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906697
HCC4006	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
H357	DepMap CRISPR Gene Dependency	1.0	2.66911
42-MG-BA	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.9644
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4798
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043618
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	2.01282
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051458
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4878
SW1990	DepMap CRISPR Gene Dependency	1.0	2.73012
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3669
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55751
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03455
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.311014
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07554
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7525-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHU022	DepMap CRISPR Gene Dependency	1.0	2.27165
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EM2	DepMap CRISPR Gene Dependency	1.0	4.22307
Uterine benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	1.85491
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79202
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059368
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22181
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0713
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897056
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.64104
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.49588
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3739
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80755
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.357
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
POLR3A_01_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.81352
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.23238
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2521
hsa-miR-708	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	1.0	null
LAMA84	CCLE Cell Line Gene CNV Profiles	1.0	1.37016
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	8.66208
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057722
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.4125
Opitz GBBB syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01142
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.125
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.36704
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.3957
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6388
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43003
Hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05103
SKNMC	DepMap CRISPR Gene Dependency	1.0	2.67366
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.41612
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5536
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82912
localizes	GeneRIF Biological Term Annotations	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4116
SNU308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48734
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	1.79254
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X4-01A-51R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Columella	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
protein binding	GO Molecular Function Annotations 2015	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7791
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.30472
CAL-33	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.9644
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Phlyctenulosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62244
Kidney Chromophobe_KICH_TCGA-KN-8426-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13681
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35394
ZNF679	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51804
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	179.04
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.485
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79529
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857904
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044883
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2782
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4621
PMC10990974-mmc2.xlsx-Curated_ERRa_interactors_112-STRING_ESRRA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06654
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0625
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102870_1_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71623
hsa-miR-4799-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
496100567_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.96502
NMB	DepMap CRISPR Gene Dependency	1.0	2.74132
NCIH1385	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63215
HS578T	CCLE Cell Line Gene CNV Profiles	1.0	1.71157
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LV-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33413
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	166.799
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0083
SCLC21H	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938499
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09323
synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.770907
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.7123
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052038
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18409
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056453
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2775
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IST-MES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0904
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13103
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99069
TIMM10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03412
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0083
CH157MN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35812
organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE216757_0_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5678
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-3.51142
SQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64399
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2876
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13103
STAU1_DELETION_GDS3370_56_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.71045
CAL12T	CCLE Cell Line Gene Expression Profiles	1.0	1.7925
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.23238
HCC1419	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50649
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855427
LS1034	DepMap CRISPR Gene Dependency	1.0	2.01822
Sperm cytoplasmic droplet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.593
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964598
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cor1/Xlr/Xmr family	InterPro Predicted Protein Domain Annotations	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80223
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18546
hsa-miR-3137	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCIH2110	DepMap CRISPR Gene Dependency	1.0	9.0944
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33643
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13966
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptonemal structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.17714
OCIAML2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77966
SPIB	JASPAR Predicted Transcription Factor Targets	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24754
adrenal gland	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05032
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40056
U87MG	CCLE Cell Line Gene Expression Profiles	1.0	1.50997
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.74778
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25323
NCIH2030	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38075
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80223
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	306.701
JHH7	CCLE Cell Line Gene Expression Profiles	1.0	1.68072
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	3.34519
OUMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.54441
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76214
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9361
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3_02_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.6845
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	1.23238
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21094
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054586
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5833
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64716
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34992
Kallmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.014
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77218
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75809
PMC10990974-mmc2.xlsx-Curated_ERRa_interactors_112-IID_ESRRA	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0203	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32375
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.00567
Uterine fibroid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7087
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979637
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057647
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.8634
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2897
Glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2057
WM793	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75058
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	1.0	1.54747
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-3160-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AM38	CCLE Cell Line Gene Expression Profiles	1.0	3.40755
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
brain	GTEx Tissue Gene Expression Profiles	1.0	1.01369
Annulate lamellae	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.117
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	264.656
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	553.909
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4151
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RI1	CCLE Cell Line Gene Expression Profiles	1.0	2.09781
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.745039
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09076
SNRK_overexpression_127_GSE30185	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-3.65675
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU387	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50023
GSE102870_7_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	2.15147
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0029
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.73161
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.92278
FUOV1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03715
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male-pattern baldness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84128
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7428
SNU761	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98091
Reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.47933
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16001
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872451
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96163
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.33844
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862706
SH10TC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52614
FOS	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-591	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
LOUCY	CCLE Cell Line Gene Expression Profiles	1.0	1.36349
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92013
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.10682
exclusively	GeneRIF Biological Term Annotations	1.0	null
Creatinine levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18409
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.9921
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26725
CAL851	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75813
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3067
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
Enamel organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61472
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.4057
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptonemal complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00576
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055935
KDM5A	ENCODE Transcription Factor Targets	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82912
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942068
Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978945
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41076
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061607
hsa-miR-410	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.40065
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S8-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33488
CJM	CCLE Cell Line Gene CNV Profiles	1.0	1.33571
HCC70	CCLE Cell Line Gene Expression Profiles	1.0	1.61206
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052801
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAC2A	DepMap CRISPR Gene Dependency	1.0	5.49833
Inguinal hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.0496
SUZ12	ENCODE Transcription Factor Targets	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6987
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100377_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.63433
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
TC71	CCLE Cell Line Gene Expression Profiles	1.0	1.42271
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19545
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
Punctate epithelial keratoconjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8955
hsa-miR-28-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Telopode	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.44923
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1_01_208	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5883
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.548
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	3.16607
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47316
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spermatid development	GO Biological Process Annotations 2025	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1772
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	2.00715
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.54081
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3044
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U2904	DepMap CRISPR Gene Dependency	1.0	10.5191
PMC10990974-mmc2.xlsx-Curated_ERRa_interactors_112-Total_ERRa_interactors_from_BioGRID_HuRI_IID_and_STRING_HUMAN_or_MOUSE_112_ESRRA	Rummagene Transcription Factor Associations 2026	1.0	null
RBM34_02_141	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.67807
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869654
PL4	DepMap CRISPR Gene Dependency	1.0	3.43678
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04221
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897056
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879772
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ZDHHC17	Pathway Commons Protein-Protein Interactions	1.0	null
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15538
hsa-miR-4738-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914634
Hydrophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-200a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54666
organelle	GO Cellular Component Annotations 2015	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.733275
EW-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.5898
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9693
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.802
reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1766
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	1.0	1.81662
SNU81	DepMap CRISPR Gene Dependency	1.0	4.30932
Nuclear chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
intracellular part	GO Cellular Component Annotations 2015	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0314
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM2664	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89902
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83434
hsa-miR-1303	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09882
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.981
PMC10990974-mmc2.xlsx-Curated_ERRa_interactors_112-BioGRID_ESRRA	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L311	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.9644
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.3242
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02633
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3846
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8518-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10037
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.3123
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.3783
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31817
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00811
CAL33	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59452
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16161
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30016
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2366
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042687
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60672
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056799
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6849