association dataset threshold value standardized value HKA1 DepMap CRISPR Gene Dependency 1.0 3.06098 GSE118816_0_v_1_myo1c_human RummaGEO Gene Perturbation Signatures 1.0 null SGHPL-4 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.956 PMC12529848-12967_2025_7217_MOESM3_ESM.xlsx-Table_S4-Table_S4_Associations_of_genetically_proxied_proteins_with_risk_of_atrial_fibrillation_by_MR-SPI_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE132948,GSE132949_0_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039738 urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.064385 Immune system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043981 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pontine gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2458 JHOS2 CCLE Cell Line Gene CNV Profiles -1.0 -3.20951 Perturb_12036_KD_Prmt6_SRP131294 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 H3K27me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE73628_8_v_2_igf1_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56273 Lymphoid follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.099 496100517_TCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.01476 DEL CCLE Cell Line Gene CNV Profiles 1.0 1.79013 FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A655-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050609 nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80865 abnormality of myeloid leukocytes GWASdb SNP-Phenotype Associations 1.0 0.195367 Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75E-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE171837_0_v_3_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39833 PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-298-ZNF610_ZNF610 Rummagene Transcription Factor Associations 2026 1.0 null EOL1 CCLE Cell Line Gene Expression Profiles 1.0 1.66693 CAOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.55579 nephron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.264696 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Fetal Death CTD Gene-Disease Associations 1.0 1.02114 Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044983 time GeneRIF Biological Term Annotations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.05724 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7101 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 UM-UC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.4875 Perturb_10320_KO_HDAC1/HDAC2_SRP255858 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.63463 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8104016-hcg-12-e002353-s010.xlsx-mTHP1-LPS_30kb-Nearest_reported_Gene_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43822 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21932 CBX2 ENCODE Transcription Factor Targets 1.0 null 496100386_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.17743 Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null kidney HPA Tissue Gene Expression Profiles 1.0 1.00041 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.065 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P300-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MYB-26560356-CHIP-SEQ-TH1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25707 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.872464 Periventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26184 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.144 GSE60837_2_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null UHO1 DepMap CRISPR Gene Dependency 1.0 2.40784 KLF4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.823944 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Intergeniculate leaflet of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32711 t67-small-intestine_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.4314 abnormal lymphocyte physiology MPO Gene-Phenotype Associations 1.0 null PMC11748740-41598_2025_85338_MOESM1_ESM.xlsx-Table_S2-Table_S2_The_cis-pQTLs_Pass_Instrumental_Variable_Selection_Test_for_Primary_MR_Analysis_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9941420-mmc1.docx-3-ZNF704_ZNF704 Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-7271-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PU-27001747-CHIP-SEQ-BMDM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null superior temporal gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.964072 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47661 hsa-miR-3607-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 bed nucleus of the stria terminalis, medioseptal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16393 hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.28698 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54429 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998616 PGA1 DepMap CRISPR Gene Dependency 1.0 7.74934 SALL4-22934838-CD34+-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null JJ012 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12871 orbital frontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0187 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.75177 Perturb_10261_KO_Esrrg_SRP119935 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.67734 SNU283 CCLE Cell Line Gene Expression Profiles 1.0 1.34968 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thymus lymphoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.955 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 portion of vagal motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18515 CAL148 CCLE Cell Line Gene CNV Profiles 1.0 1.67 496100385_TCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.42087 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GL-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lower basal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77143 GSE151829,GSE151831_1_v_8_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null Entorhinal area, medial part, dorsal zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74474 Cortical microtubule cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.205 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948474 PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3 Rummagene Transcription Factor Associations 2026 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.883143 GSE164463_2_v_1_pax6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-44-2657-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal memory B cell differentiation MGI Mouse Phenotype Associations 2023 1.0 null Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.186 Fetallung BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.866319 SR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874698 Dorsal premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1996 ICC106 DepMap CRISPR Gene Dependency 1.0 3.14767 nephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.326646 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DD-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36391 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35424 HCC1143 CCLE Cell Line Gene Expression Profiles -1.0 -1.83772 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25V-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE92364_0_v_3_asparaginase_mouse RummaGEO Drug Perturbation Signatures 1.0 null MECP2_KD_GDS4759_334_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null abnormal mature b cell morphology MPO Gene-Phenotype Associations 1.0 null 496100356_TCx_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00811 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14645 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948474 Six3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.513 SK-ES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Follicular dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.219 abnormal spleen secondary b follicle morphology MPO Gene-Phenotype Associations 1.0 null dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.160224 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100332_HIP_possible Alzheimer's disease_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1109 abnormal immune system physiology MPO Gene-Phenotype Associations 1.0 null 496100410_TCx_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.71832 PDK1_knockout_80_GSE26290 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.214476 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.22416 D542MG DepMap CRISPR Gene Dependency 1.0 2.13711 Perturb_16739_KO_Gcn5_SRP271119 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -16.2195 JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15785 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040732 Primary somatosensory area, lower limb, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87929 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 48.1044 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null NANOG-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Primary motor area, Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05688 hsa-miR-4493 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Perturb_259_KD_PBRM1_SRP358304 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8151 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GSE145476_1_v_0_hopx_mouse RummaGEO Gene Perturbation Signatures -1.0 null leukocyte disease GWASdb SNP-Disease Associations 1.0 0.323726 Mesangial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.28 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13627 Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11032 increased spleen germinal center size MPO Gene-Phenotype Associations 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40471 Acute Myeloid Leukemia_LAML_TCGA-AB-2924-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Atherosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.142 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.951462 H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE168797_2_v_0_cannabidiol_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_9261_KO_Ifng_ERP010742 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.38888 GSE151829,GSE151831_7_v_0_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.320956 lymphnode_5a HPA Tissue Sample Gene Expression Profiles 1.0 1.06522 SUPM2 DepMap CRISPR Gene Dependency 1.0 5.34225 Type 1 diabetes mellitus_Thymic epithelial cell_GSE11 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.45217 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58018 Germinal center TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.527 MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.49 Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16268 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0299 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null entorhinal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30571 Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0991 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.52412 RELA_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RXR-22158963-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KARPAS-1106P COSMIC Cell Line Gene Mutation Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54932 mantle zone of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69824 c-Rel MotifMap Predicted Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Malaria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.062 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.833235 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.167856 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-387 COSMIC Cell Line Gene Mutation Profiles 1.0 null NEUROD2-26341353-CORTEX-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RUNX1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9402 NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46561 GSE135705_5_v_3_corticosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null lateral part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33866 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.42794 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormal b cell differentiation MPO Gene-Phenotype Associations 1.0 null Entorhinal area, medial part, dorsal zone, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7999 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null PMC12503973-3972293.f8.xlsx-Supplementary_table7-Supplementary_Table_8_MR-PRESSO_Results_in_the_Discovery_and_Replication_Phases_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null shedding GeneRIF Biological Term Annotations 1.0 null P31FUJ DepMap CRISPR Gene Dependency 1.0 2.10904 hsa-miR-326 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_13-Table_13_MR_Steiger_analysis_to_infer_the_MR_causal_orientation_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE180200,GSE180201_3_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE158715_3_v_0_cyp1b1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100284_FWM_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18154 Ectorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14211 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.63814 lymphnode_4a HPA Tissue Sample Gene Expression Profiles 1.0 0.880796 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936122 outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.854652 PANC1005 DepMap CRISPR Gene Dependency 1.0 2.00598 SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2852 WAOSEL DepMap CRISPR Gene Dependency 1.0 5.30357 Influenza DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.198 Perturb_10839_KO_Xbp1_SRP197108 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.43654 GSE160373_6_v_2_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947438 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.930417 GSE77108_3_v_2_saha_human RummaGEO Drug Perturbation Signatures 1.0 null IgA glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.79 EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 110.257 bladder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.137755 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46561 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05692 primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.88566 central medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.859857 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null inner SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.873103 RPS6KA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02518 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08142 GSE157594_0_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null membrane LOCATE Curated Protein Localization Annotations 1.0 null mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.17517 abnormal follicular dendritic cell physiology MPO Gene-Phenotype Associations 1.0 null Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11466 M14 COSMIC Cell Line Gene Mutation Profiles 1.0 null ERF::NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.6235 EBF1-22473956-BONE-MARROW-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210476_2_v_3_rutaecarpine_human RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43045 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43953 GSE143847_2_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures 1.0 null Mono-Mac-6 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.978 Lateral reticular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49024 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01223 UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null LMTK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63914 abnormal neutrophil cell number GWASdb SNP-Phenotype Associations 1.0 0.591893 KDM1A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of ERCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30571 Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.564 CTCF-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CRX-20693478-RETINA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Entorhinal area, medial part, dorsal zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.58524 IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6798 PMC4279731__F7 PFOCR Pathway Figure Associations 2024 1.0 null GSE158197_0_v_4_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null HNF4 MotifMap Predicted Transcription Factor Targets 1.0 null SUP-M2 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 HUPT4 CCLE Cell Line Gene CNV Profiles -1.0 -1.64385 PMC12869252-mmc1.xlsx-ST19-Supplementary_Table_19_Results_of_MR_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null p107_Deficiency_GDS3176_606_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null GSE228727_2_v_1_dapagliflozin_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC8104016-hcg-12-e002353-s010.xlsx-mTHP1-LPS_30kb-Interacting_Gene_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null SUPM2 CCLE Cell Line Gene CNV Profiles 1.0 2.71303 HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.37607 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7718 COLO704 CCLE Cell Line Gene CNV Profiles 1.0 1.35711 IRF4_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.8358 REST_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.851932 143B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.831683 Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.328 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79365 PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1 Rummagene Transcription Factor Associations 2026 1.0 null eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175683_1_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE146747_0_v_1_nr4a1_mouse RummaGEO Gene Perturbation Signatures 1.0 null RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal b cell physiology MPO Gene-Phenotype Associations 1.0 null GSE210476_2_v_0_rutaecarpine_human RummaGEO Drug Perturbation Signatures -1.0 null SPI1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09534 tissues GeneRIF Biological Term Annotations 1.0 null MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68491 superficial stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24794 rhesus GeneRIF Biological Term Annotations 1.0 null GSE166920_6_v_5_adalimumab_human RummaGEO Drug Perturbation Signatures 1.0 null 496100625_FWM_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57006 Hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.234 abnormal b cell morphology MPO Gene-Phenotype Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 1 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.58524 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.951942 KLF15_KO_GDS4780_509_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.33541 SPI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH526 CCLE Cell Line Gene CNV Profiles -1.0 -1.5318 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null GSE132948,GSE132949_0_v_5_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null ELK1 ChEA Transcription Factor Targets 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null REST ENCODE Transcription Factor Targets 1.0 null periventricular stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45244 GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null mantle zone of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27923 r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15636 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40981 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04463 OSR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8894 KMS26 CCLE Cell Line Gene CNV Profiles 1.0 1.378 Whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.144 DV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95332 hsa-miR-671-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 periventricular stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18515 vermiform appendix TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.754124 GSE176008_7_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1977 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal follicular dendritic cell antigen presentation MPO Gene-Phenotype Associations 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.836005 nucleus of the central acoustic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23549 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 tlr4 GeneRIF Biological Term Annotations 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Perturb_1124_KO_Myc_SRP168941 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GSE221356_1_v_0_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null amygdaloid complex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.85044 EPLC-272H COSMIC Cell Line Gene Mutation Profiles 1.0 null fusiform gyrus, left, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.936518 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30456 dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21417 Complement component C1q complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.402 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72141 abnormal follicular dendritic cell antigen presentation MGI Mouse Phenotype Associations 2023 1.0 null Bone inflammation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 layer 2 of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94803 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.09685 posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13735 CCK81 CCLE Cell Line Gene Expression Profiles 1.0 1.6495 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HDQP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49195 GSE180200,GSE180201_3_v_11_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46973 nucleus of the stria terminalis, medial division, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08017 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34751 CRO-AP2 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.917 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04466 primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.97292 Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFE2L1_02_32 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 5.08215 Medial amygdalar nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46424 primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02474 Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.111 Lamina propria TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.314 abnormal leukocyte physiology MPO Gene-Phenotype Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lymph node TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.56284 TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51045 RCOR1-19997604-NEURONS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.515005 leukopenia GWASdb SNP-Disease Associations 1.0 0.373907 PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3 Rummagene Transcription Factor Associations 2026 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02705 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 hsa-miR-330-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.619961 PNGase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.518 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NB13 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07566 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.90713 Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59878 Medial septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10837 abnormal spleen germinal center morphology MPO Gene-Phenotype Associations 1.0 null HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947438 lymphoid tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.285316 kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.338177 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.926989 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE220520_5_v_7_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0959 Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26184 phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078126 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PU1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RDES CCLE Cell Line Gene Expression Profiles -1.0 -2.12221 Presubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05331 Epididymis disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39067 PMC12749580-42003_2025_9274_MOESM5_ESM.xls-Supplementary_Data_2B-Supplementary_Table2B_Full_results_of_the_proteome-wide_MR_in_Ukb_ppp_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.881013 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.15651 Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.871396 ESS1 CCLE Cell Line Gene Expression Profiles -1.0 -2.2691 Perturb_10313_OE_hAPOL1_G2_SRP075245 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5367 RI1 DepMap CRISPR Gene Dependency 1.0 8.44776 PMC4821877-ncomms10846-s9.xlsx-THP1_Splice_events-Gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null lateral tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60774 GSE180200,GSE180201_3_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null renal corpuscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.420004 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.337 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.95211 SNU1327 DepMap CRISPR Gene Dependency 1.0 3.85392 Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.3172 Excretory gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.141 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.838106 mantle zone of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67776 GSE146074_6_v_7_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null lateral hypothalamic area, mammillary region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21778 GSE172020_0_v_2_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null HCC70 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.820428 anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39561 105KC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.949546 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.0259 LIM1215 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-1236 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Perturb_15371_KD_TP53_SRP294453 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_6161_KO_Kdm1a_SRP200436 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.9046 dimer GeneRIF Biological Term Annotations 1.0 null MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.725514 fh67 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.197 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37303 ZFX_KD_GSE43021_130_human_NOMO1 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.67146 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7594-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.35979 GSE100732,GSE100733_0_v_1_lrpprc_mouse RummaGEO Gene Perturbation Signatures -1.0 null ICAM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30406 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null ES5 DepMap CRISPR Gene Dependency 1.0 4.98608 SNU407 CCLE Cell Line Gene CNV Profiles 1.0 1.66822 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00913 abnormal memory b cell differentiation MPO Gene-Phenotype Associations 1.0 null pre-B cell receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.781 hsa-miR-384 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Retrosplenial area, dorsal part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06981 Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal marginal zone B cell physiology MGI Mouse Phenotype Associations 2023 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE146687_2_v_1_eribulin_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_10312_OE_hAPOL1_G1_SRP075245 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Dorsal motor nucleus of the vagus nerve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40023 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null p3 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02132 Fra-1_KO_GDS5078_402_mouse_Lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null EBC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.32663 Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_16732_KO_3110043O21Rik_ERP013119 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.2211 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49953 Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCIAML2 CCLE Cell Line Gene Expression Profiles 1.0 1.75756 r2 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38517 Brain Lower Grade Glioma_LGG_TCGA-DU-7015-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null first GeneRIF Biological Term Annotations 1.0 null YMB1 CCLE Cell Line Gene CNV Profiles 1.0 2.07951 G43417UB GlyGen Glycosylated Proteins 1.0 null Coronary Arteriosclerosis DisGeNET Gene-Disease Associations 1.0 null SA1-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null paraterete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90681 thus GeneRIF Biological Term Annotations 1.0 null abnormality of neutrophils GWASdb SNP-Phenotype Associations 1.0 0.378748 layer 2 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83118 Palatine tonsil TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.548 PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53687 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.65844 GSE220693_1_v_0_cgas_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09795 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05166 21152935-TableS1 GeneSigDB Published Gene Signatures 1.0 null HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87125 hsa-miR-4275 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Primary somatosensory area, lower limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00668 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.314772 KYSE150 CCLE Cell Line Gene CNV Profiles -1.0 -1.54711 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_10840_KO_Xbp1_SRP262377 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.31836 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.997152 r3 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38031 hsa-miR-615-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE202744_1_v_3_toyocamycin_human RummaGEO Drug Perturbation Signatures 1.0 null IST-MES1 COSMIC Cell Line Gene Mutation Profiles 1.0 null U178 CCLE Cell Line Gene Expression Profiles -1.0 -1.63523 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36853 nfkappab GeneRIF Biological Term Annotations 1.0 null THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81K-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15396 GSE157594_6_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null NCIH2023 CCLE Cell Line Gene Expression Profiles -1.0 -1.6959 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04124 substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.02271 GSE174498,GSE174500_3_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95332 Parasitic infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.06 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.879335 mantle zone of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31471 Skin - Sun Exposed (Lower leg) GTEx Tissue Gene Expression Profiles 2023 1.0 4.20696 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54774 superficial stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16996 periventricular stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0388 organelle LOCATE Predicted Protein Localization Annotations 1.0 null T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22096 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.898766 ATF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100606_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.2374 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0803 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GV-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 rostral group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.87904 r9 part of the lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72671 496100406_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.80502 cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.37689 NCIH446 CCLE Cell Line Gene Expression Profiles -1.0 -1.78605 horsetail-astral microtubule array COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.297 Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PU.1-20176806-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_2029_KO_Chd4_SRP173193 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.55325 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MERO25 DepMap CRISPR Gene Dependency 1.0 4.30675 UACC812 CCLE Cell Line Gene CNV Profiles 1.0 2.30839 Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15027 r1 part of vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33452 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.38433 Immunoglobulin-like domain InterPro Predicted Protein Domain Annotations 1.0 null r10 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33866 OCUM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.74035 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE229914_1_v_3_keap1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE146074_1_v_7_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46766 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8492 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.60282 UMUC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.98383 Perturb_15370_KD_TP53_SRP294453 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 BHLHE40 ENCODE Transcription Factor Targets 1.0 null CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BL3627 (KDM3A) NURSA Protein Complexes 1.0 null bc96 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.609 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.92153 Viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.168 GSE73561,GSE73563_0_v_1_mef2c_mouse RummaGEO Gene Perturbation Signatures 1.0 null IKZF1 ENCODE Transcription Factor Targets 1.0 null Nr5a2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4192 induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64367 GSE193541_1_v_2_nifurtimox_human RummaGEO Drug Perturbation Signatures 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72213 Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integral component of membrane GO Cellular Component Annotations 2015 1.0 null fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057956 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4161-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RELA ENCODE Transcription Factor Targets 1.0 null GSE246195,GSE246305_4_v_5_sin3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.840936 TEN CCLE Cell Line Gene Expression Profiles 1.0 1.48411 H3K27me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAPK1_knockdown_45_GSE12291 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.61152 MERO83 DepMap CRISPR Gene Dependency 1.0 2.05324 PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-gene_name_POU3F4 Rummagene Transcription Factor Associations 2026 1.0 null Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.0866 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21714 H3K27me3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100547_HIP_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.58461 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null layer 4 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36985 GSE207582_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC3998024__F2 PFOCR Pathway Figure Associations 2024 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.44162 juvenile rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.722077 EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64121 MV411 DepMap CRISPR Gene Dependency 1.0 5.34872 layer 3 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20513 SUIT-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.949546 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2703 GSE85880,GSE85881_0_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null icSARS CoV_7Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.87026 Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.025 Caput epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.91 BATF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 KCL-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12109_KO_Kdm1a_SRP200436 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.01818 lymph node TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.983103 EP300_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal mononuclear cell morphology MPO Gene-Phenotype Associations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.883263 amygdaloid complex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.829414 Entorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14911 Immunoglobulin complex, circulating COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.67 PMC12422825-aging-17-8-206293-s003.xlsx-i_MR_IP-Unnamed_5_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null DBH_KO_GDS4324_362_mouse_Embryonic heart E10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39511 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25712 GSE152441,GSE152442_0_v_4_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null Parasubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.30565 ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57475 intermediate pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3656 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0191 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03827 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null layer 1 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.82413 SW1271 CCLE Cell Line Gene CNV Profiles -1.0 -1.62261 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.319863 496100546_TCx_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.74482 r9 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72738 CAOV4 DepMap CRISPR Gene Dependency 1.0 2.50466 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.3471 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE119345_2_v_3_bexarotene_human RummaGEO Drug Perturbation Signatures -1.0 null upregulate GeneRIF Biological Term Annotations 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null GSE70499_4_v_1_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12043 POU2F2 ENCODE Transcription Factor Targets 1.0 null Immunoglobulin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.335 Perturb_10327_KO_Anxa1_SRP377197 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.6986 GSE158197_0_v_11_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.931362 Retinoschisis_Retina_GSE5581 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -0.328488 Perturb_16721_KO_Brca1_SRP094855 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.5528 bone inflammation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.076627 PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_16-Table_16_Information_of_genetic_instruments_used_for_Mendelian_randomization_MR_analysis_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.98884 abnormal immune system morphology MPO Gene-Phenotype Associations 1.0 null cytoplasmic part LOCATE Curated Protein Localization Annotations 1.0 null Hyperplasia CTD Gene-Disease Associations 1.0 1.05535 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.92227 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.88431 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01223 PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_9-Table_9_The_association_of_genetically_predicted_levels_of_proteins_with_the_risk_of_coronary_heart_disease_CHD_by_MR_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null r10 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16268 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04272 Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.277 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.9119 plasma membrane GO Cellular Component Annotations 2015 1.0 null GSE234340_4_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GATA1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE184902_4_v_0_adipor1_mouse RummaGEO Gene Perturbation Signatures 1.0 null LP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.88079 MJ DepMap CRISPR Gene Dependency 1.0 6.01923 GSE98898_4_v_1_hoxa1_human RummaGEO Gene Perturbation Signatures 1.0 null Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.8208 Bed nuclei of the stria terminalis, posterior division, principal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64489 GSE208254_3_v_2_irf8_mouse RummaGEO Gene Perturbation Signatures -1.0 null MCF7 CCLE Cell Line Gene CNV Profiles 1.0 1.43407 MAFK_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.62807 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE165579_3_v_2_opa1_mouse RummaGEO Gene Perturbation Signatures 1.0 null tonsil_8b1 HPA Tissue Sample Gene Expression Profiles 1.0 0.92064 abnormal professional antigen presenting cell physiology MPO Gene-Phenotype Associations 1.0 null TP53-18474530-U2OS-human ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 600MPE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.13763 Systemic lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.009 Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.353 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990612 GSE146074_10_v_3_ly6e_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100550_TCx_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20158 connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047804 p1 portion of the paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07632 peripheral blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.099681 Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 APLN_KO_GDS3228_601_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06507 kidney_b HPA Tissue Sample Gene Expression Profiles 1.0 1.01703 ventral posterolateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33176 496100334_PCx_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.1705 Pontocerebellar hypoplasia type 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.051 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09534 CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21985 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08628 Perturb_16941_KO_Mkrn1_SRP149173 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.46659 HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SW620 CCLE Cell Line Gene Expression Profiles -1.0 -1.96904 Perturb_16696_KO_31O21Rik_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.55889 Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PK59 CCLE Cell Line Gene CNV Profiles -1.0 -1.91269 primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.831578 Perturb_6137_KO_Yap1/Wwtr1_SRP314027 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.0805 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040524 Perturb_17732_KO_Tmprss2_SRP046010 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.098 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.6432 GSE70499_3_v_1_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null fusiform gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.824827 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D4-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162015_1_v_0_nfkb1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE220520_6_v_8_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.1737 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.087466 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948474 496100417_HIP_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.11959 immune system phenotype MPO Gene-Phenotype Associations 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null Hypoglossal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30571 NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3248 NCIH1299 CCLE Cell Line Gene CNV Profiles -1.0 -1.53125 SP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13359 GSE220520_6_v_9_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.277197 YAP_OE_GDS3220_32_human_MCF10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.64951 macrophages GeneRIF Biological Term Annotations 1.0 null abnormality of granulocytes GWASdb SNP-Phenotype Associations 1.0 0.294545 abnormality of leukocytes GWASdb SNP-Phenotype Associations 1.0 0.174408 TP53-18474530-U2OS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.9892 GSE220520_3_v_0_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null mammalian phenotype MPO Gene-Phenotype Associations 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null mantle zone of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63997 dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.57531 NCCLMS1C1 DepMap CRISPR Gene Dependency 1.0 2.4864 GSE133516_5_v_3_kat7_human RummaGEO Gene Perturbation Signatures -1.0 null HS600T CCLE Cell Line Gene Expression Profiles -1.0 -1.57506 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null hsa-miR-485-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Ventral posterolateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70989 kidney_d HPA Tissue Sample Gene Expression Profiles 1.0 1.0973 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.156 planum polare, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24933 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.49171 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058421 posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35118 HCC78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03396 Lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52486 icSARS CoV_3Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.550816 20140255-TableS2 GeneSigDB Published Gene Signatures 1.0 null Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.2419 plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11917_KO_Apoe_SRP135284 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.23455 LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.3267 Perturb_10235_KD_EXOC5_SRP187300 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 intermediate stratum of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33962 hsa-miR-3692 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00812 CTCF ENCODE Transcription Factor Targets 1.0 null 20502458-TableS6a GeneSigDB Published Gene Signatures 1.0 null Hypersensitivity vasculitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.201 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43841 SOX6-21985497-MYOTUBES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE110248_1_v_6_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.858988 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null supramarginal gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.85561 OVCAR4 CCLE Cell Line Gene CNV Profiles -1.0 -1.40409 superficial stratum of PrS (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31471 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null GSE220520_3_v_8_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null 496100489_HIP_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02606 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060302 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.65597 Brain - Amygdala GTEx Tissue Gene Expression Profiles 2023 1.0 5.72128 follicular dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.03653 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.165231 abnormal leukocyte count GWASdb SNP-Phenotype Associations 1.0 0.378748 EFM-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_16666_KO_Tfr2_ERP107589 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.12303 MOLP2 CCLE Cell Line Gene CNV Profiles -1.0 -1.38834 GSE88819_0_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QQ-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fcalphar GeneRIF Biological Term Annotations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE101336_1_v_3_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16271 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.883263 Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX3 ENCODE Transcription Factor Targets 1.0 null TC32 CCLE Cell Line Gene CNV Profiles 1.0 1.47991 intestinal GeneRIF Biological Term Annotations 1.0 null GSE172020_1_v_2_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.917635 MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null B3GALT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87603 lower dorsal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21465 LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null OCT4-21477851-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MTA3 ENCODE Transcription Factor Targets 1.0 null Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.8384 b-lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.576015 hematopoietic system phenotype MPO Gene-Phenotype Associations 1.0 null GSE166920_6_v_3_adalimumab_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01223 Ectorhinal area/Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0822 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.852452 PMC7730811-13148_2020_983_MOESM1_ESM.xlsx-Table_S3D_HNF1A_Target_Genes-Table_S3D_HNF1A_Target_Genes_Average_Colon_HNF1A Rummagene Transcription Factor Associations 2026 1.0 null paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36815 Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51761 planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.843361 GSE137914_0_v_3_tet3_mouse RummaGEO Gene Perturbation Signatures -1.0 null HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7995 integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.14438 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11582803-41598_2024_80483_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_MR_analysis_of_Proteome_wide_Mendelian_Randomization_FinnGen_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null intermediate stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20698 Entorhinal area, medial part, dorsal zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.8236 TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CDX2-21402776-INTESTINAL-VILLUS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PPARG JASPAR Predicted Transcription Factor Targets 1.0 null NF-kappaB MotifMap Predicted Transcription Factor Targets 1.0 null BCLAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95332 abnormal spleen b cell follicle morphology MPO Gene-Phenotype Associations 1.0 null shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06299 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39462 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MTMR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84291 kidney cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060991 polymorphisms GeneRIF Biological Term Annotations 1.0 null pro-b-lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.677803 Perturb_9572_KO_Acvr1b_DRP005835 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.50065 HT115 CCLE Cell Line Gene Expression Profiles 1.0 1.92179 Endopiriform nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14211 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 primary auditory cortex (core)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.974324 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27107 occipito-temporal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.900172 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU3F1-26484290-ESCSS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mantle zone of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40023 abnormal immune cell physiology MPO Gene-Phenotype Associations 1.0 null mantle zone of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34011 GSE166004_5_v_4_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cos-7 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.247719 wehi279 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.953 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58018 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2 Rummagene Transcription Factor Associations 2026 1.0 null fenofibrate_homo sapiens_gpl4044_gse15494 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null abnormal blood cell physiology MPO Gene-Phenotype Associations 1.0 null Trachea BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.86598 Perturb_11291_KO_Bmal1_SRP060296 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.54623 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null Bed nucleus of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46123 outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12715 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0803 Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 56.3578 Perturb_4434_KO_Cnb1_SRP312336 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09534 Lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.13 HDAC1 ENCODE Transcription Factor Targets 1.0 null MZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.17351 SUPHD1 CCLE Cell Line Gene CNV Profiles 1.0 2.79307 activates GeneRIF Biological Term Annotations 1.0 null GSE229580_2_v_1_creb1_human RummaGEO Gene Perturbation Signatures -1.0 null required GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lymph node HPA Tissue Gene Expression Profiles 1.0 0.895214 Perturb_1006_KO_Bcl9l/Bcl9_SRP045828 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.922 nucleus of the diagonal band, left, vertical division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63837 Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0694 Ventral posteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79079 Spinal nucleus of the trigeminal, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33498 Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0425 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.45803 Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SOX2-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.834746 Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKHEP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.65034 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.932573 CAL-12T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01432 8505C DepMap CRISPR Gene Dependency 1.0 4.75324 kidney BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.04408 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.85 STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null heart GTEx Tissue Gene Expression Profiles -1.0 -1.31375 GSE240645_1_v_0_u90926_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNU61 CCLE Cell Line Gene Expression Profiles 1.0 1.84843 spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.42082 orbital frontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.955164 intermediate stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17126 Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CD-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null increased spleen germinal center size MGI Mouse Phenotype Associations 2023 1.0 null Midbrain reticular nucleus, retrorubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39658 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3807_KO_Irf1_SRP151536 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.93224 hsa-miR-637 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE168797_2_v_3_cannabidiol_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00073 iga glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.681096 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Glaucoma_Retina_GSE3554 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.37304 NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.90071 AML193 DepMap CRISPR Gene Dependency 1.0 2.39446 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2261 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GX-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null monocyte-derived dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.466111 H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lateral part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63875 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.59162 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null upper basal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35118 GSE239457_1_v_0_rasa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE146074_1_v_11_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null abnormal hematopoietic system morphology/development MPO Gene-Phenotype Associations 1.0 null SALL4 ChEA Transcription Factor Targets 1.0 null LRF MotifMap Predicted Transcription Factor Targets 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null Arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35547 GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE151829,GSE151831_1_v_0_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null Peyer's gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.534 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31167 KDM1A ENCODE Transcription Factor Targets 1.0 null hsa-miR-4713-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 efficient GeneRIF Biological Term Annotations 1.0 null Ventral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03182 AMO1 CCLE Cell Line Gene CNV Profiles -1.0 -2.16347 OVCAR8 CCLE Cell Line Gene CNV Profiles -1.0 -2.59196 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54308 Primary somatosensory area, upper limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02838 integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.363185 Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05956 pro-B-lymphocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.185 abnormal antigen presentation MPO Gene-Phenotype Associations 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-1245b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064369 hsa-miR-485-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 abnormal hematopoietic system physiology MPO Gene-Phenotype Associations 1.0 null SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19065 B cell deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.181 Perturb_1123_KO_Myc_SRP168941 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.92481 RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.98878 GSE151829,GSE151831_7_v_8_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.8723 IgA B cell receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.228 Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE220813_0_v_1_zfp750_mouse RummaGEO Gene Perturbation Signatures -1.0 null midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.53933 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.872596 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15438 Arsenic CTD Gene-Chemical Interactions 1.0 null Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21969 EBF1 ENCODE Transcription Factor Targets 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.868274 lateral hypothalamic area, tuberal part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.983858 GSE185744,GSE185747_2_v_3_sox9_human RummaGEO Gene Perturbation Signatures -1.0 null ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1128_KO_Myc_SRP168941 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.5168 Perturb_7574_KO_SF3B1_SRP342911 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.9465 globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15886 pro-b-lymphocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.17447 hsa-miR-3139 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GATA2_02_28 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.70044 r7 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16354 primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44118 r10 part of vagal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45244 MAFF ENCODE Transcription Factor Targets 1.0 null MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0196 PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-3929 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 frontal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07281 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07655 HCS2 DepMap CRISPR Gene Dependency 1.0 4.04288 CMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KMS28BM CCLE Cell Line Gene Expression Profiles 1.0 1.43386 hsa-miR-4697-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE203485_1_v_0_sunitinib_human RummaGEO Drug Perturbation Signatures 1.0 null 1321N1 CCLE Cell Line Gene Expression Profiles -1.0 -2.12491 PMC3998024__F2 PFOCR Pathway Figure Associations 2023 1.0 null membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.238837 abnormal lymphopoiesis MPO Gene-Phenotype Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IKZF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Aortic root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.709 iPS-18 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.11482 PMC6591464-Table_4.xlsx-Sheet_1-AIRE_regulated_genes_TRA_annotated_AIRE Rummagene Transcription Factor Associations 2026 1.0 null layer 5 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17001 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null KYSE-450 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE220520_3_v_4_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0285 WM88 CCLE Cell Line Gene CNV Profiles 1.0 1.40035 GSE149901_3_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures -1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.4766 Perturb_9560_KO_Marchf3_SRP278315 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.39234 Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.122 H3K27me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.842406 EBF1-22473956-LYMPHODE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null liver GTEx Tissue Gene Expression Profiles 1.0 1.35577 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spinal nucleus of the trigeminal, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25055 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16732 MS751 DepMap CRISPR Gene Dependency 1.0 2.96149 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9413 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23405 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.315 mantle zone of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30571 Acute Myeloid Leukemia_LAML_TCGA-AB-2818-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVTOKO CCLE Cell Line Gene Expression Profiles 1.0 1.363 PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_name_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null intermediate stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72877 cell surface COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.169099 Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.43791 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.77566 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.963246 OCILY3 CCLE Cell Line Gene Expression Profiles 1.0 1.45419 CA-SKI COSMIC Cell Line Gene Mutation Profiles 1.0 null KLF15_KO_GDS4780_419_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Immunoglobulin subtype InterPro Predicted Protein Domain Annotations 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37082 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH650 CCLE Cell Line Gene CNV Profiles -1.0 -1.51778 RORC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9128 mesangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.578016 abnormal somatic hypermutation frequency MPO Gene-Phenotype Associations 1.0 null H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null occurring GeneRIF Biological Term Annotations 1.0 null agranulocytosis GWASdb SNP-Disease Associations 1.0 0.690184 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3333 Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.896 paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0694 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOGGUVW CCLE Cell Line Gene Expression Profiles -1.0 -2.71453 TP53 Pathway Commons Protein-Protein Interactions 1.0 null PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27102 abnormal leukocyte morphology MPO Gene-Phenotype Associations 1.0 null Aster COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.076 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -2.8696 ventral part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72141 abnormal memory b cell morphology MPO Gene-Phenotype Associations 1.0 null GSE166920_6_v_8_adalimumab_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH508 CCLE Cell Line Gene CNV Profiles -1.0 -1.53457 GSE223893_2_v_10_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null surface GeneRIF Biological Term Annotations 1.0 null lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.256568 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 Entorhinal area, lateral part, layer 2a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57683 abnormal adaptive immunity MPO Gene-Phenotype Associations 1.0 null abnormal cell-mediated immunity MPO Gene-Phenotype Associations 1.0 null KMS21BM CCLE Cell Line Gene CNV Profiles 1.0 1.54584 GSE180200,GSE180201_12_v_6_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5045-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHOP cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.763 Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.58524 MDAMB134VI CCLE Cell Line Gene Expression Profiles -1.0 -1.47008 HNF4A Pathway Commons Protein-Protein Interactions 1.0 null SALL4-22934838-CD34+-HUMAN ChEA Transcription Factor Targets 2022 1.0 null polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.854726 Perturb_4500_KO_zc3h12a_DRP003625 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.0257 interstitial nucleus of the zona limitans Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17126 b-lymphocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.328262 Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.9557 abnormal spleen white pulp morphology MPO Gene-Phenotype Associations 1.0 null hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.326067 P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_1420_OE_Aatf_SRP257744 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.62835 HCC56 CCLE Cell Line Gene Expression Profiles 1.0 1.60646 GSE73628_1_v_2_igf1_human RummaGEO Gene Perturbation Signatures 1.0 null RELA_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null increased spleen germinal center number MPO Gene-Phenotype Associations 1.0 null NCIH82 CCLE Cell Line Gene Expression Profiles -1.0 -1.61752 fibroblast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060042 CTCF_GM12865_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 small intestine GTEx Tissue Gene Expression Profiles 1.0 0.852213 p2 part of the zona limitans core population Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08634 NCIH526 CCLE Cell Line Gene Expression Profiles -1.0 -2.02893 GSE166054_1_v_0_klf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE174735_1_v_3_il22_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC7730811-13148_2020_983_MOESM1_ESM.xlsx-Table_S13A_HNF1A_Targets_Genes-Unnamed_1_HNF1A Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8133-01A-12R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13286 MAFK ENCODE Transcription Factor Targets 1.0 null Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.2452 amygdaloid complex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.856281 GSE77108_5_v_2_saha_human RummaGEO Drug Perturbation Signatures 1.0 null AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.949546 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adam10 GeneRIF Biological Term Annotations 1.0 null GSE172295_3_v_2_sh3gl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.592 LN382 DepMap CRISPR Gene Dependency 1.0 3.89621 GSE94849_6_v_4_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-11A-12R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.234 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15423 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53505 SW1463 CCLE Cell Line Gene Expression Profiles 1.0 1.38641 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.92751 BATF ENCODE Transcription Factor Targets 1.0 null hsa-miR-188-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.901978 PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.168 CHD1 ENCODE Transcription Factor Targets 1.0 null GSE203485_1_v_0_zdhhc2_human RummaGEO Gene Perturbation Signatures 1.0 null Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19415 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23987 intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null GSE109913_1_v_2_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null membrane GO Cellular Component Annotations 2015 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.81545 Lung adenocarcinoma_LUAD_TCGA-55-7574-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04701 MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.93616 hsa-miR-571 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Perturb_16775_KO_Utx/Jmjd3_SRP339500 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.67113 PMC10515843-media-1.xlsx-Table_7_Diff_loop_genes_E_v_S-Supplementary_Table_7_Genes_that_involve_significant_differential_looping_in_pediatric_primary_B_cell_CTCF_peaks_compared_to_GM12878_CTCF_peaks_CTCF Rummagene Transcription Factor Associations 2026 1.0 null layer 4 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65839 endosome LOCATE Curated Protein Localization Annotations 1.0 null 17284527-Table2 GeneSigDB Published Gene Signatures 1.0 null hematopoietic system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9276 Medullary reticular nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0672 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30576 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.871344 MZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3175 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04971 cecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.311145 macaques GeneRIF Biological Term Annotations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7050-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.1024 Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72004 transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04859 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.027071 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A86F-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP4::ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.1054 superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31259 RCOR1-19997604-NEURONS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SLR20 CCLE Cell Line Gene Expression Profiles -1.0 -1.56357 NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-708 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 r5 part of the oral Sp5 subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20702 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.6094 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29288 intermediate part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39067 GSE200982_0_v_2_plac8_human RummaGEO Gene Perturbation Signatures -1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25813 AMO1 DepMap CRISPR Gene Dependency 1.0 2.40788 GSE137144_2_v_6_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null portion GeneRIF Biological Term Annotations 1.0 null Mesangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.333 PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6177 GSE172020_0_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null UMRC6 CCLE Cell Line Gene Expression Profiles 1.0 2.13733 KE37 DepMap CRISPR Gene Dependency 1.0 3.14748 SP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29715 basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36985 membrane LOCATE Predicted Protein Localization Annotations 1.0 null ileocecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.180253 Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64183 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57082 Immunoglobulin-like fold InterPro Predicted Protein Domain Annotations 1.0 null HCC1187 DepMap CRISPR Gene Dependency 1.0 3.77623 Cell surface interactions at the vascular wall Reactome Pathways 2024 1.0 null olfactorybulb BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.11071 GSE144838_7_v_8_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZFX-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null abnormal immune system cell morphology MPO Gene-Phenotype Associations 1.0 null hsa-miR-199b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2152 A2780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04543 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CY-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Leukemialymphoblastic(MOLT-4) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.23169 H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.84142 MCF 10A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95332 Sox6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.1727 Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17523_KO_Dcaf1_SRP194105 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.36962 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03807 stratum oriens of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32673 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null parasubthalamic nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05331 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5262-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44445 Lung adenocarcinoma_LUAD_TCGA-55-8208-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_11-Table_11_The_association_of_genetically_predicted_levels_of_proteins_with_the_risk_of_HF_by_MR_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.847048 r4 part of descending trigeminal sensory nucleus, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2475 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null periventricular stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03288 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECC12 CCLE Cell Line Gene CNV Profiles 1.0 1.49286 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70875 GSE132948,GSE132949_0_v_1_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TSC22D4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27262 GSE143212_0_v_3_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11704 CDK8_knockdown_147_GSE32108 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.61664 Lymphoid tissue TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE220520_1_v_7_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210476_11_v_10_rutaecarpine_human RummaGEO Drug Perturbation Signatures 1.0 null MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52727 Kidney BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.838465 EP300 ENCODE Transcription Factor Targets 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22802 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.914595 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.25457 PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63797 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.11021 abnormal blood cell morphology/development MPO Gene-Phenotype Associations 1.0 null mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null MRK-NU-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 abnormal marginal zone b cell physiology MPO Gene-Phenotype Associations 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35531 kidney_a HPA Tissue Sample Gene Expression Profiles 1.0 0.906517 RCC4 CCLE Cell Line Gene Expression Profiles 1.0 1.95369 Arteriosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.134 TAF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70613 Rectum adenocarcinoma_READ_TCGA-F5-6813-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null GSE208254_3_v_1_irf8_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29036 superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64183 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.57149 pregeniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43305 RPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17592 RELA_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.757937 PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-160-ZNF20_ZNF20 Rummagene Transcription Factor Associations 2026 1.0 null midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.95145 DOR 13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.949546 superficial stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38031 SCC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.229299 mbl2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.726 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.67349 GSE241036_4_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null r6 part of spinal trigeminal nucleus, pars oralis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30707 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26727 outer CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08684 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 JHOS4 CCLE Cell Line Gene CNV Profiles 1.0 1.36647 bw-5147 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.985859 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.08646 BATF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06299 Lung adenocarcinoma_LUAD_TCGA-75-6212-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ONS76 DepMap CRISPR Gene Dependency 1.0 5.15392 amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.909497 Presubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67776 HT55 CCLE Cell Line Gene Expression Profiles 1.0 1.52399 Plasma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.547 GSE176008_4_v_1_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null AGS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95332 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.339282 medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.81691 hsa-miR-4731-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 primary motor cortex (area M1, area 4)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17242 TP63 ChEA Transcription Factor Targets 1.0 null r8 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13526 ZNF684 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.964 abnormal spleen germinal center morphology MGI Mouse Phenotype Associations 2023 1.0 null KINGS1 DepMap CRISPR Gene Dependency 1.0 2.60075 GSE121824,GSE121826_0_v_3_scaf8_human RummaGEO Gene Perturbation Signatures -1.0 null PMC8755441-mmc3.xlsx-IRF1-Down-Symbol_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09953 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null SESN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93288 PHGDH_KO_GDS2874_125_mouse_embryonic head tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2955 OCT4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null humans GeneRIF Biological Term Annotations 1.0 null GSE172295_1_v_2_sh3gl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null lymphoid tissue TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11027 POU2F2_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.949546 WM-266-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.836597 central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.989683 posterobasal nucleus, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11466 CAL62 DepMap CRISPR Gene Dependency 1.0 3.01189 GSE77108_8_v_2_saha_human RummaGEO Drug Perturbation Signatures 1.0 null KMS27 DepMap CRISPR Gene Dependency 1.0 2.66664 GSE180200,GSE180201_2_v_6_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.262986 Perturb_16712_KO_Ppbp_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.82252 PET complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.61 LS411N CCLE Cell Line Gene Expression Profiles 1.0 1.39484 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4635 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 Bed nuclei of the stria terminalis, posterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28418 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE196671_6_v_8_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC7730811-13148_2020_983_MOESM1_ESM.xlsx-Table_S13A_HNF1A_Targets_Genes-Table_S13A_HNF1A_Targets_Genes_HNF1A Rummagene Transcription Factor Associations 2026 1.0 null DU4475 CCLE Cell Line Gene CNV Profiles 1.0 1.78307 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27132 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.5457 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68749 MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.68553 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.938222 abnormal lymphocyte morphology MPO Gene-Phenotype Associations 1.0 null rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.163523 NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4872 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855442 ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.324 ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14814 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21417 GSE181966_5_v_3_has2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12823428-43587_2025_1018_MOESM3_ESM.xlsx-ST12-Supplementary_Table_12_Main_mendelian_randomisation_results_of_plasma_proteins_on_delirium_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null 496100361_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.02904 PMC8582123-13073_2021_996_MOESM4_ESM.xlsx-SATB1-HIT_SATB1 Rummagene Transcription Factor Associations 2026 1.0 null GSE242367_1_v_0_dpp9_human RummaGEO Gene Perturbation Signatures 1.0 null Membrane attack complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.031 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65007 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE165647_2_v_3_cry2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Lymph node TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37866 cellular_component GO Cellular Component Annotations 2015 1.0 null GSE242367_1_v_0_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null K562 DepMap CRISPR Gene Dependency 1.0 3.07938 GNG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20211 Entorhinal area, medial part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21465 primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61024 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A710-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902198 long insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945324 Lung adenocarcinoma_LUAD_TCGA-55-6983-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7730811-13148_2020_983_MOESM1_ESM.xlsx-Table_S3C_HNF4A_Target_Genes-Table_S3C_HNF4A_Target_Genes_Average_Colon_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10322668-Table_7.xlsx-DE_genes_at_early_infection-List_of_de-regulated_genes_at_early_interaction_time_point_of_Dm28c_T_cruzi_THP1_infected_cells_From_Libisch_2020_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null RCOR1 ChEA Transcription Factor Targets 1.0 null SNU324 CCLE Cell Line Gene CNV Profiles 1.0 2.0216 urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.330827 Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.1365 Retrosplenial area, lateral agranular part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.45246 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11357 NCI-H520 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE132759_4_v_2_fgfr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormal somatic hypermutation frequency MGI Mouse Phenotype Associations 2023 1.0 null p38mapk GeneRIF Biological Term Annotations 1.0 null NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.98398 PMC12693071-NIHMS2120882-supplement-8.xlsx-Sheet1-scWGS_analysis_of_the_M486_AR_model_AR-specific_or_-enriched_CNV_genes_involved_in_apoptosis_immune_regulation_and_or_known_ICI_resistance_pathways_AR Rummagene Transcription Factor Associations 2026 1.0 null alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0564 Perturb_16537_KO_Lsd1_ERP114763 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.44373 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.65905 NCOR1-26117541-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null extracellular region COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.183935 PMC11257892-Table_1.xlsx-S2-Supplementary_Table_S2_All_results_of_the_preliminary_MR_analysis_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null organelle LOCATE Curated Protein Localization Annotations 1.0 null pathways GeneRIF Biological Term Annotations 1.0 null 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null spleen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.146267 Fc-epsilon receptor I complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.777 ELK1-22589737-MCF10A-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Hypersensitivity reaction type III disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.094 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.965578 PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC Rummagene Transcription Factor Associations 2026 1.0 null Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.958078 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null GSE77108_4_v_2_saha_human RummaGEO Drug Perturbation Signatures 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.69847 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null CBX8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1663 abnormal immune system organ morphology MPO Gene-Phenotype Associations 1.0 null GABPA ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCUB-M COSMIC Cell Line Gene Mutation Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20104 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2741 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45T-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.28397 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.87946 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.82626 p3 portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17491 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34553 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parasubiculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67776 Perturb_12063_KO_Stat5a/Stat5b_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30617 rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.498667 Ciliary pocket COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.682 ZR751 CCLE Cell Line Gene CNV Profiles 1.0 2.16839 cell part LOCATE Curated Protein Localization Annotations 1.0 null hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.9064 Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10132 kidney GTEx Tissue Gene Expression Profiles 1.0 1.46442 TAL1 ENCODE Transcription Factor Targets 1.0 null CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29055 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.954233 CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.945742 KE39 CCLE Cell Line Gene CNV Profiles -1.0 -1.44622 leukopenia GWASdb SNP-Phenotype Associations 1.0 0.591893 REH DepMap CRISPR Gene Dependency 1.0 2.44755 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.133557 Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymph node TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.234 r9 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01044 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adenocarcinoma of lung_Lung Tissue_GSE11969 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.97774 PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_id_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null NB13 DepMap CRISPR Gene Dependency 1.0 2.74046 Human - Tonsil - L2 - cycling FDC HuBMAP Azimuth Cell Type Annotations 1.0 null SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40314 NMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null 496100337_HIP_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.59659 orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.56832 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_12061_KO_Stat5a_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE223893_11_v_10_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2434 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16539 ventral part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27923 496100339_HIP_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0021 cell part GO Cellular Component Annotations 2015 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15785 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF4 ChEA Transcription Factor Targets 1.0 null Anteromedial nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10916 COV413A DepMap CRISPR Gene Dependency 1.0 3.66215 Perturb_18120_KO_Tfap2b_SRP196877 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.3202 GSE130217_0_v_3_sesn2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE138019_4_v_6_nudt12_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_Fetal Heart Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate stratum of PHyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90681 spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.42082 Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precuneus, left, inferior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11018 THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.7418 KP1N DepMap CRISPR Gene Dependency 1.0 2.33569 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57362 Fc-alpha receptor I complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.546 Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5154 GSE220520_3_v_9_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null lymphnode_4b HPA Tissue Sample Gene Expression Profiles 1.0 0.868328 Primary somatosensory area, lower limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71123 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27172 G120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.983213 P2URK562 DepMap CRISPR Gene Dependency 1.0 5.06023 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.839845 SKLMS1 CCLE Cell Line Gene CNV Profiles -1.0 -2.03667 IgM immunoglobulin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.474 BW-5147 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.982 Perturb_13623_KD_Kdm1a_SRP148688 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.23433 GSE158815_1_v_3_trib1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Micronuclei, Chromosome-Defective CTD Gene-Disease Associations 1.0 1.2013 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.232599 SNUC4 CCLE Cell Line Gene Expression Profiles 1.0 2.31783 RBP2_deficiency_GDS2731_62_mouse_embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE133516_0_v_1_kat7_human RummaGEO Gene Perturbation Signatures 1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.841629 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998616 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998616 GSE146074_9_v_11_ly6e_mouse RummaGEO Gene Perturbation Signatures 1.0 null hypothalamus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.03559 GSE166920_6_v_4_adalimumab_human RummaGEO Drug Perturbation Signatures 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SAP30 ENCODE Transcription Factor Targets 1.0 null GSE181966_0_v_3_has2_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of cellular immune system GWASdb SNP-Phenotype Associations 1.0 0.174408 naturally GeneRIF Biological Term Annotations 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89836 posteromedial visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37723 HS729 CCLE Cell Line Gene CNV Profiles -1.0 -1.77669 MERO82 DepMap CRISPR Gene Dependency 1.0 3.33442 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 72.104 tonsil_8e1 HPA Tissue Sample Gene Expression Profiles 1.0 0.852752 GSE240645_3_v_2_u90926_mouse RummaGEO Gene Perturbation Signatures -1.0 null SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.983213 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE220520_6_v_0_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null ATF2 ENCODE Transcription Factor Targets 1.0 null Glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.561 abnormal spleen morphology MPO Gene-Phenotype Associations 1.0 null Ventral part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91335 hsa-miR-1257 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SARS-CoV NSP16_Day2_None_GSE49263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.96026 Arteriosclerotic cardiovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.141 GSE148695,GSE167281_2_v_1_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE199255,GSE199356_6_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null MV411 CCLE Cell Line Gene Expression Profiles 1.0 1.71288 Aspartate carbamoyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.761 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.848559 HCC202 CCLE Cell Line Gene CNV Profiles 1.0 1.32842 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PYROXD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55629 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.82626 Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 all GWASdb SNP-Phenotype Associations 1.0 0.032383 STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41759 hsa-miR-4488 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.889622 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75314 Henoch-Schoenlein purpura DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.209 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.53298 GSE199921_1_v_0_romidepsin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYA-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null t61-colon_consensus MoTrPAC Rat Endurance Exercise Training 1.0 3.40216 Lung adenocarcinoma_LUAD_TCGA-55-A48X-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ISTMEL1 DepMap CRISPR Gene Dependency 1.0 3.13633 Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12062_KO|KO_Stat5a|Stat5b_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15127 PMC4858740-ncomms11473-s2.xls-HAdV-D9_cr1b_Library_1-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null GSE207582_4_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null RKN CCLE Cell Line Gene CNV Profiles -1.0 -2.35219 IgE immunoglobulin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.563 outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.977902 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.76829 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3186 lymphoid follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.12748 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.882428 periventricular stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06299 ZR7530 CCLE Cell Line Gene CNV Profiles 1.0 1.50274 NHLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53444 NFE2-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null r1 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25791 AU565 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.26743 Perturb_261_KD_PBRM1_SRP358304 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Mesenteric lymph node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.904 Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0388 Perturb_16740_KO_Gcn5_SRP271119 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.1051 PCGF2-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null EZH2-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840809 GSE137144_2_v_7_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null B-lymphocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.131 Aortic intima TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.752 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87125 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12494 MDAMB175VII CCLE Cell Line Gene Expression Profiles -1.0 -1.50209 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25991 STAT3-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null increased spleen germinal center number MGI Mouse Phenotype Associations 2023 1.0 null GSE92364_1_v_3_asparaginase_mouse RummaGEO Drug Perturbation Signatures 1.0 null abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.100901 GSE241701_4_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null neutropenia GWASdb SNP-Phenotype Associations 1.0 0.591893 LS180 CCLE Cell Line Gene Expression Profiles 1.0 1.79747 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2121 Immune system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.234 Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU520 CCLE Cell Line Gene Expression Profiles 1.0 1.5458 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36908 Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10132 ELK1-22589737-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null OSRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.56847 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DY-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE172189_0_v_1_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2767 GSE157594_6_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_12074_OE_Carm1_SRP134253 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.60111 CBX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23854 intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38031 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null superficial stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90681 CW2 CCLE Cell Line Gene Expression Profiles 1.0 3.40791 Urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.144 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IgM B cell receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.173 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE184902_4_v_0_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21985 GSE234340_10_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of PaS (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67776 Presubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72141 GSE75976_3_v_4_abl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE160373_8_v_2_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null CBX8 ENCODE Transcription Factor Targets 1.0 null GSE206270_1_v_0_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.966252 retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48665 PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-Unnamed_0_POU3F4 Rummagene Transcription Factor Associations 2026 1.0 null r8 part of linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3229 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87125 G361 CCLE Cell Line Gene CNV Profiles -1.0 -1.54153 GSE128634,GSE128636_1_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.887387 KIJK CCLE Cell Line Gene CNV Profiles 1.0 1.34488 WBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21654 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-11A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_16303_KO_Esr1_SRP115139 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 hsa-miR-635 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19656 Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064284 internalization GeneRIF Biological Term Annotations 1.0 null PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_10-Table_10_The_association_of_genetically_predicted_levels_of_proteins_with_the_risk_of_stroke_by_MR_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GATA1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null WSU-FSCCL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04701 HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.959747 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LPS510 DepMap CRISPR Gene Dependency 1.0 6.90287 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.08 PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2 Rummagene Transcription Factor Associations 2026 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.02445 IgA immunoglobulin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.533 thymus lymphoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.962903 PU.1-20513432-BCELLS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null layer 3 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01 presubiculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31471 CEBPB ENCODE Transcription Factor Targets 1.0 null GSE70499_5_v_1_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null immune system disease GWASdb SNP-Disease Associations 1.0 0.053641 ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1415 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.851061 LMSU DepMap CRISPR Gene Dependency 1.0 2.33554 SNUC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.58104 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43841 primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22997 abnormal leukopoiesis MPO Gene-Phenotype Associations 1.0 null medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25074 lps GeneRIF Biological Term Annotations 1.0 null 496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.69466 Perturb_16764_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6796-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1563 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20702 UMUC13 DepMap CRISPR Gene Dependency 1.0 2.41967 Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.955376 NCIH1385 CCLE Cell Line Gene Expression Profiles -1.0 -1.46648 large intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072434 FLI1-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6815 HNRNPL_02_160 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.70044 basal part of terminal hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15572 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE144231_2_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fcamr GeneRIF Biological Term Annotations 1.0 null H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE138019_1_v_2_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null 17284527-TableS1 GeneSigDB Published Gene Signatures 1.0 null GSE255432_7_v_3_imeglimin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GATA6-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.8917 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50535 nucleus subceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.911152 DUSP1_Deficiency_GDS1606_765_mouse_Spleen GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1 ENCODE Transcription Factor Targets 1.0 null STK33 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null PMC4279731__F7 PFOCR Pathway Figure Associations 2023 1.0 null hsa-miR-3142 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0803 RELA_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null foam cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.446038 EZH2 ENCODE Transcription Factor Targets 1.0 null H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null GSE158197_6_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_9608_KO_Sirt7_SRP223932 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Hemostasis Reactome Pathways 2024 1.0 null AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null mesangial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.663962 layer 2 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20513 ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.900741 L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874698 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15127 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.883263 OCI-AML3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95332 Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCI-30 COSMIC Cell Line Gene Mutation Profiles 1.0 null stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25952 Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STK33_SKM MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null superficial stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10132 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08766 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.883263 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 lateral periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10132 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.981155 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.3457 r9 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2458 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FBXL15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88016 B cell receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.181 renal glomerulus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.452969 CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE137914_0_v_5_tet3_mouse RummaGEO Gene Perturbation Signatures -1.0 null RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.92252 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.144 tonsil_8a1 HPA Tissue Sample Gene Expression Profiles 1.0 1.09783 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.89987 GSE210476_2_v_7_rutaecarpine_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-28-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 superficial stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81963 caudal group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.64169 striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.87534 survey GeneRIF Biological Term Annotations 1.0 null HNF1A Pathway Commons Protein-Protein Interactions 1.0 null cv-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.173611 hsa-miR-369-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.833593 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.993102 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JM1 CCLE Cell Line Gene CNV Profiles 1.0 1.43191 GSE158197_2_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null 201T COSMIC Cell Line Gene Mutation Profiles 1.0 null MDAMB453 CCLE Cell Line Gene CNV Profiles 1.0 1.9281 Perturb_15278_OE_Foxa1_SRP189075 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.2546 Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.144 superficial stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30347 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.990009 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.92021 lymphoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.090865 LU135 DepMap CRISPR Gene Dependency 1.0 2.74192 YAPC CCLE Cell Line Gene CNV Profiles -1.0 -1.40562 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.30116 kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.078007 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.825541 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null KP-N-RT-BM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13066 peduncular nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83189 H3K27me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IRF4 ENCODE Transcription Factor Targets 1.0 null granule cell layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09493 Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null adam17 GeneRIF Biological Term Annotations 1.0 null Fc receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.53 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null C84 DepMap CRISPR Gene Dependency 1.0 2.65041 Nucleus ambiguus, dorsal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03789 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35118 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Epididymitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.019 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Schizont TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.699 formation GeneRIF Biological Term Annotations 1.0 null hsa-miR-199a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 LU134A DepMap CRISPR Gene Dependency 1.0 2.1103 urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.323144 CBX2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NFIC ENCODE Transcription Factor Targets 1.0 null GSE246195,GSE246305_4_v_3_sin3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_1912_KO_Prkcd_SRP386893 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.5883 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSU DepMap CRISPR Gene Dependency 1.0 2.00765 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.276 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76O-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.86707 Prostate adenocarcinoma_PRAD_TCGA-J4-A6G1-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0469 Perturb_16579_KO_Crebbp_SRP174041 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.28995 temporal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19756 17284527-TableS2 GeneSigDB Published Gene Signatures 1.0 null H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10828500-41467_2024_44701_MOESM4_ESM.xlsx-ST12-Unnamed_7_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Entorhinal area, lateral part, layer 2b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02132 MYOG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5086 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.997152 Perturb_1131_KO_Myc_SRP168941 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.79654 ERI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60162 Leukemia_promyelocytic-HL-60 BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.28101 TCF4-18268006-LS174T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_15280_OE_Foxa1_SRP189075 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.3188 lymphoid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.101901 GSE123502,GSE123504_1_v_0_chd4_mouse RummaGEO Gene Perturbation Signatures -1.0 null RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.0891 immune system process GO Biological Process Annotations 2015 1.0 null STAT3 MotifMap Predicted Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE220520_1_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null tonsil HPA Tissue Gene Expression Profiles 1.0 0.981334 periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16432 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5249-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null comprehensive GeneRIF Biological Term Annotations 1.0 null Zbtb2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.1119 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.959872 Perturb_3828_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.09736 GSE169713,GSE169715_1_v_2_tert_mouse RummaGEO Gene Perturbation Signatures 1.0 null inner CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48996 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9226 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.77365 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.78596 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20104 TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3244 Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3ER-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE174498,GSE174500_2_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null cos cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.183238 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.2461 peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0694 KPNSI9S CCLE Cell Line Gene CNV Profiles 1.0 1.67241 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null Exocrine glandular secretion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.87 BECKER CCLE Cell Line Gene Expression Profiles -1.0 -2.31617 HDAC6 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE180277_0_v_1_bach2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cancer of prostate_Prostate_GSE1413 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.51841 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.533 TP53 ChEA Transcription Factor Targets 1.0 null AKT1_knockdown_123_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.66631 Immunoglobulin alpha deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.249 SW756 COSMIC Cell Line Gene Mutation Profiles 1.0 null intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.114775 NB7 DepMap CRISPR Gene Dependency 1.0 2.2881 Perturb_1139_KO_Ahr_ERP113014 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.31621 Spinal nucleus of the trigeminal, oral part, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56877 CD40/CD40L signaling PID Pathways 1.0 null Perturb_12064_KO_Stat5a/Stat5b_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SKM1 CCLE Cell Line Gene Expression Profiles 1.0 1.49825 fcalphamur GeneRIF Biological Term Annotations 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62434 PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.01285 G28T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911802 KMRC1 CCLE Cell Line Gene Expression Profiles 1.0 2.65491 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1189 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE168798_0_v_1_isg15_human RummaGEO Gene Perturbation Signatures -1.0 null OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null SUM149PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.708511 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.929365 abnormal hematopoiesis MPO Gene-Phenotype Associations 1.0 null Nephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.498 SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE164463_3_v_1_pax6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.3703 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70257 Arthritis, Juvenile Rheumatoid HuGE Navigator Gene-Phenotype Associations 1.0 null RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1906 NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cytoplasmic GeneRIF Biological Term Annotations 1.0 null CDK19_knockdown_148_GSE32108 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.96077 Immunoglobulin V-set domain InterPro Predicted Protein Domain Annotations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ventral posterolateral nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52657 layer 3 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65839 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE145476_2_v_0_hopx_mouse RummaGEO Gene Perturbation Signatures -1.0 null lower basal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53508 NR4A1_02_84 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.33985 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20237 PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13 Rummagene Transcription Factor Associations 2026 1.0 null r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29308 Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.55714 Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18515 TCF4-18268006-LS174T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6911 hsa-miR-4711-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 SP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02041 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09806 skeletalmuscle BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.19496 BT483 CCLE Cell Line Gene CNV Profiles 1.0 1.42692 DBH_KO_GSE33906_53_mouse_heart (E10.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null substantia innominata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.890093 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80M-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP63_01_202 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.77221 SC-163 (CDK2) NURSA Protein Complexes 1.0 null abnormal professional antigen presenting cell morphology MPO Gene-Phenotype Associations 1.0 null DUSP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79176 LEF1-29337183-MESC-MOUSE-STEM ChEA Transcription Factor Targets 2022 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05085 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.65214 GSE77108_6_v_2_saha_human RummaGEO Drug Perturbation Signatures 1.0 null PC3 CCLE Cell Line Gene CNV Profiles 1.0 1.5908 GSE196671_5_v_0_obox4_mouse RummaGEO Gene Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.60708 GP2D CCLE Cell Line Gene Expression Profiles 1.0 2.32421 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.873981 Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.1747 LDB1-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE130864_0_v_1_tincr_mouse RummaGEO Gene Perturbation Signatures -1.0 null RINm5F cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.631 GSE180200,GSE180201_5_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE139987_1_v_0_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null dactinomycin_homo sapiens_gpl7172_gse12459 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.57022 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02803 hematopoietic system disease GWASdb SNP-Disease Associations 1.0 0.106077 agranular insular cortex (area Iag) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09032 Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45067 hilus of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56273 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44109 neutropenia GWASdb SNP-Disease Associations 1.0 0.690184 lymphoid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.255234 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57905 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.3431 hsa-miR-4708-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC Rummagene Transcription Factor Associations 2026 1.0 null PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE172020_1_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.977239 ETV5::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.2878 GSE60837_0_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures 1.0 null SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.16184 lymphoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.104278 NELFE ENCODE Transcription Factor Targets 1.0 null Hematopoietic system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MAFF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 496100341_TCx_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30046 SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE138019_1_v_5_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null HUT78 CCLE Cell Line Gene Expression Profiles 1.0 2.04778 glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.386308 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1368 LPS853 DepMap CRISPR Gene Dependency 1.0 3.40959 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20513 intermediate stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01231 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.163 GSE214335_1_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null G-361 COSMIC Cell Line Gene Mutation Profiles 1.0 null BCLAF1 ENCODE Transcription Factor Targets 1.0 null