association	dataset	threshold value	standardized value
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55636
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04052
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.497
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2897
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43052
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253155
PMC10823279-CAS-115-283-s001.xlsx-Table_S6-Table_S6_List_of_182_genes_particularly_down-regulated_by_AR_in_AILNCaP14_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.471376
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01892
BTBD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55808
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	3.68215
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0122
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99999
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078292
Retinitis pigmentosa 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07556
Thymus-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	4.52455
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56198
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09016
Endocrine pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.34
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74043
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.75
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961991
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.89068
PMC8314029-12931_2021_1797_MOESM5_ESM.xlsx-DE_genes_in_ACDMPV-Gene_name_FOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
RA-49-ZB08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373244
EFR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53318
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32181
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0511
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841353
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28795
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278606
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067626
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6913
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66367
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0212
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21554
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16442
Catalytic step 1 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3628
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83872
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081575
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38632
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84277
SLC52A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49491
CB-73-HZ47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202737
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.723942
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8745
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59848
Bruck syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19199
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.951784
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050974
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63562
Cingulate gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.501
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060662
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052253
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50681
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36096
fat_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03039
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38173
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91639
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06146
CRCGN016_MCF10A.WT.HP_24H:M05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46527
ZNF687	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84001
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27284
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29913
MOLT-4 cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225727
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28264
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966495
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.50323
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22018
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7338
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18584
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:J12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1364
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40986
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9987
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61641
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
Bladder	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.3111
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53604
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29027
CHRNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8056
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07265
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894109
JD-00-YJ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263517
Chloroplast photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.632389
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23511
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72907
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5781
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9576
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331356
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94135
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51092
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12144
DB-88-VW47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238191
CA-25-LR28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236082
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37913
dilated heart	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19304
NY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUP-T1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8993
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.24138
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949152
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06893
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11689
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87039
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.58722
abnormal trabecula carnea morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	2.17174
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.486
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81829
skin	GTEx Tissue Gene Expression Profiles	1.0	0.930464
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95412
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052901
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50445
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14901
RAB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61188
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.587444
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98233
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.24979
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873037
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479581
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48636
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
t-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21573
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.93045
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12717
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04364
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22217
Sarcoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32989
ZBTB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2294
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0222
TRIM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45426
MAPKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37815
ZNF608	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99953
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7998
QKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83771
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951407
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857443
md86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.579772
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13232
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.78014
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02386
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
FOXP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27859
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988215
FF-46-OR35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31059
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246461
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82024
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
ALDH18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70625
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829973
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42607
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84958
abnormal myocardium layer morphology	MGI Mouse Phenotype Associations 2023	1.0	null
IA-03-BO30_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375286
Myosin IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904821
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02229
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824279
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11058
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923973
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.318272
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333564
KCTD20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83199
ARID4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81512
496100428_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52371
integument	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72783
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998679
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1056
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04555
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1609
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972718
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34879
BZW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67921
pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.300173
GTEX-S4Q7-0426-SM-3K2BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05411
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.39533
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33253
BNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75374
GABARAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61522
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88666
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01315
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2601
ATXN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86719
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33012
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59236
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06027
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16074
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850101
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053165
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88158
SULT1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91906
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888111
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39018
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5289
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52265
AE-06-FY47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.420598
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
WASF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57667
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71282
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963853
JUND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70196
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74546
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05619
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862647
[Ni-Fe] hydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6519
enlarged heart	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47709
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82081
RRAGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86196
H2BC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38932
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41204
BAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69707
KCTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02287
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950875
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.60871
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85091
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27105
Lymphocytic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
Mitotic checkpoint complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932636
DRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72037
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057905
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.20226
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08014
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.875749
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59695
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25313
TDRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8689
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01501
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854869
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96754
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90656
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847681
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.6457
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6919
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5377
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54485
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64026
placenta_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.894843
rpmi7666	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71064
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_2_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00348
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9356
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84577
BF-00-PE90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217457
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66896
ISGF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
AA-56-QO38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204643
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37521
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24786
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056679
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072008
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.733947
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86855
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
MTMR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73603
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.44673
VK-2/E6E7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08263
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968371
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267958
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.7972
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
a431	HPA Cell Line Gene Expression Profiles	1.0	1.54423
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.797165
FF-54-JC89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270376
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20167
ED-15-OX47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285308
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43237
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855522
NCOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46391
thin ventricular wall	MGI Mouse Phenotype Associations 2023	1.0	null
AA-91-SB25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231113
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.362273
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0241
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204745
Protein phosphatase type 2A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.631
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41708
Penis_Foreskin_Fibroblast_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.915008
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.721802
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61593
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5655
EPOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96372
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067579
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
ZNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89956
NC-27-AD53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291704
LE-60-VC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2343
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086199
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47188
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057472
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6071
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15437
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67047
Endoplasmic reticulum quality control compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
Flemming body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
Olfactory lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.347
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51213
Translation initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
NE-94-VE83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209387
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06578
HILPDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39002
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61594
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.734626
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7668
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454126
Acute promyelocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
PLBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83276
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52569
Theileriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
RCC-FG2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.531089
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449018
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.914155
decreased ventricle muscle contractility	MGI Mouse Phenotype Associations 2023	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041901
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.860649
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870012
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.73638
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95364
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2841
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3012
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52618
AF-73-HJ84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260677
Pick body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
fibrodysplasia ossificans progressiva	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05429
SLC7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30346
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5707
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5083
CRCGN016_MCF10A.TP53.M_24H:B15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.27492
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3349
hut-78 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.808134
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.76119
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60566
ZNF692	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96087
CRCGN017_MCF10A.TP53.M_24H:C06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.21462
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44724
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98139
Carbon phosphorus lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
respiratory epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35672
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053029
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.12672
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988784
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42296
CRCGN008_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14572
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22527
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32384
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12926
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79003
496100447_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2353
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12422
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06188
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108346
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1925
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1082
DNAAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88968
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059847
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.493142
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.637
ARHGAP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78962
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04511
Autosomal recessive cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26681
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.635
YB-58-IZ37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.745105
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860911
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3125
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.616985
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60981
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04856
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04612
Cranial ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.088
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26628
Lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
PC3-MM2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35445
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
LRATD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74053
APBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98765
tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16293
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59125
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	1.0	0.860631
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.169
Perturb_11219_KO_SMYD3_SRP396801	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
GD-08-JL45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.560442
sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.829034
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430211
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.87797
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869252
BE-82-TS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263318
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43651
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886377
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76292
Buccal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837966
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69844
CHSY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47385
SIX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91708
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0754
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25432
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16312
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00918
LE-33-GL18_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230883
PHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79858
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7474
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25618
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846041
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58661
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41151
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054481
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01492
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7983
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34715
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
Retinoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40279
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990995
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092688
Pi Mi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0762
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273134
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960169
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319134
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
Acute promyelocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
GTEX-Q2AH-1726-SM-3NB2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39383
Slow muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.867552
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08463
RGC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
ND-36-VC68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207084
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46843
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6038
T-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828673
Blood-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.525879
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1227
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60978
BACE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45814
bj	HPA Cell Line Gene Expression Profiles	1.0	1.05009
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12856
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.838271
bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.544318
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14099
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047218
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361103
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.338
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336696
GA-79-DW49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219223
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
exencephaly	MGI Mouse Phenotype Associations 2023	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.072
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271347
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54455
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1945
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01008
GTEX-NPJ8-0226-SM-48TBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04844
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884728
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.02037
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09237
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.751078
GSE132433,GSE132436_1_v_0_nr2f2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.229
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00282
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10646
FF-22-NB12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266943
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43806
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.251
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6849
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17731
Final leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70568
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.88263
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
Osteogenesis imperfecta type 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
Spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.275
GDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86365
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6493
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58748
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861592
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84631
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.46
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69638
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89925
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.921881
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94011
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69929
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.63701
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1067
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257917
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240247
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2779
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68862
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6269
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03485
ECE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66715
FOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05467
Periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.227
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932847
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.64802
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.00865
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.01313
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.97847
DC-84-CJ21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256682
FB-56-IR20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207396
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.57032
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02308
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15223
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48031
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.268
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058918
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064964
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87941
CRCGN016_MCF10A.WT.HP_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23239
CHMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28634
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14206
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.11466
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8201
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37264
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3722
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18613
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48213
Mitotic spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69658
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93609
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79492
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.564434
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
Promyelocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54834
MA-96-GW26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20628
GNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21415
KMT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78098
ONECUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07625
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18149
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206307
limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469987
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881089
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07644
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60804
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.332
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.67615
ABCF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58469
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.733133
SH2D2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14153
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15192
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97339
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056458
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2254
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80653
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187226
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
EA-02-ZO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219783
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26534
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81937
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
Cleavage furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5853
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01375
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992217
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48102
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22942
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25211
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
496100443_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10584
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.31702
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23486
HD-51-KD29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241435
JD-00-YJ41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226043
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.18321
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.0439
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70696
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80219
respiratory distress	MGI Mouse Phenotype Associations 2023	1.0	null
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34021
Leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.162604
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69601
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08851
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052588
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64129
MIS12/MIND type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
ERCC6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68397
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.825886
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073452
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26131
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94309
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebral gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.501
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06466
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059013
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8565
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.49587
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51199
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35659
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
SIG-M5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CE-95-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33501
S0-EE-XMXE_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264979
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077944
lethality throughout fetal growth and development, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324239
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82601
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911843
Spinal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.146
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83564
Nasopharynx epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
MRPL50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64013
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439039
TMED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55973
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.620594
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.131
XC-88-ZM66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20564
Thymus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.6
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867865
MA-96-GW26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202672
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61484
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932036
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59256
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984935
Embryonic brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.325
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18264
H3C10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01377
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67887
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49507
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25045
increased heart weight	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08131
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835436
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03155
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861792
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
FA-65-UA27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335017
N1-S1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978566
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05495
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30564
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325701
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993102
dilated heart atrium	MGI Mouse Phenotype Associations 2023	1.0	null
ERBB4-ERBB4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29043
YA-85-VH07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27292
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22283
GTEX-S4Q7-1126-SM-4AD6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85983
GTEX-PWOO-1526-SM-48TCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877833
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838376
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05461
CNOT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06726
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556565
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.637
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834664
open neural tube	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.47163
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40248
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80735
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183804
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62947
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840463
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059266
FF-46-OR35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270036
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.986853
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27904
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855021
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.30985
TRPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62733
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11774
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
SC-50-ME48_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248115
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944512
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952679
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846795
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06211
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.24424
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.605
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05114
AE-51-ZO26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339119
FZD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53015
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00213
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54183
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14097
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825329
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.533877
KA-71-CQ35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.621872
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6389
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35569
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.0381
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
MI8-5 CHO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.201
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25038
TBL1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260908
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71501
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10737
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204002
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4716
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54101
Intake of sweets	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14849
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mild cognitive impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058008
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.129624
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51535
IE-80-DC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344532
TTLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64014
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.90752
Neostriatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.904
BNIP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49539
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.68108
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95307
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
Actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90969
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4087
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.509214
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954991
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849922
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6065
Mitochondrial crista junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03501
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.94205
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62008
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58298
NCAPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13215
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327164
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174447
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0423
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3986
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27131
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88793
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33287
Crfk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255567
IRF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31248
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
EEC syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4253
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.922699
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
ZNF555	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56455
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28708
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27943
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278465
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948967
Trigeminal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.088
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21237
AGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95411
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843947
SLC43A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77258
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896586
lung	GTEx Tissue Gene Expression Profiles	1.0	1.03002
HEP_3B2_1-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14474
EF-01-LB20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.332832
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.25691
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.43855
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49067
SC-50-ME48_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.290842
Eye cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
Sarcoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2032
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31593
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.197
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06124
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8999
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64626
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63707
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05816
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66274
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942365
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68767
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
TALL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30902
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49197
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
Mbiii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
cofilin-actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.982
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.472
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55247
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09975
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Protein kinase CK2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.679
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08697
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9514
FOXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16462
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5879
496100430_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53578
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	GO Biological Process Annotations 2025	1.0	null
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZMAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71306
hmc1	HPA Cell Line Gene Expression Profiles	-1.0	-0.925041
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83282
neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070609
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972325
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77852
dilated cardiomyopathy	MGI Mouse Phenotype Associations 2023	1.0	null
Endometrial cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24076
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075791
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96812
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.14764
PRKCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54357
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71488
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383952
AA-79-SX47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252739
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07496
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86141
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2494
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1004
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58838
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901857
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4556
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46904
CD-16-KY17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.712106
congestive heart failure	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12193
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862658
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055725
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052164
PBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66666
CRCGN008_HEPG2_24H:C15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25038
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912237
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.97
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.874071
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.785
NDUFA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26757
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055293
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31729
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.912
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09693
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84368
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.25926
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1383
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02265
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.46
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.394
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38519
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044068
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06008
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18272
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312695
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85115
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00848
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37285
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042896
THY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06086
PLOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68781
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054742
SETD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73004
RTBDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3889
DRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22621
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1077
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051423
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0685
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49674
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48965
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89266
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1748
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02192
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.2442
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7971
C6orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21083
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77218
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.97703
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.084653
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.875749
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47937
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
magnesium-dependent protein serine/threonine phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.625
regulation of transforming growth factor beta receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
CRCGN017_MCF10A.WT.HP_24H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42963
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5061
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02416
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272121
LCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76563
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72522
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21945
appendices_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.952703
Omk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
BC-26-LE04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294559
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3298
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9232
CRCGN015_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06527
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203663
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.962146
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.656785
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.2398
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4593
AC-80-DI95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213707
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.285316
CRCGN016_MCF10A.TP53.M_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27224
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946287
TBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46002
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42308
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0911
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32648
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055989
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.22633
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_3_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901073
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04326
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0543
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067084
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.445875
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10976
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6686
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.913
FD-25-KX07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277456
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41784
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54334
bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NDUFA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03598
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39368
LYPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63665
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5731
COPS7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43988
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25902
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63943
Pons	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.472
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95326
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	3.15128
SLC35F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29728
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5441
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	0.988227
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.379444
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96072
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7545
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18433
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02011
QB-35-FO29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242845
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.421776
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bronchial epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.074
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886891
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95689
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.434438
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25175
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89154
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.986682
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	1.4734
STX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
AHRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96819
GTEX-WI4N-1426-SM-3LK7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936414
AC-83-LN99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251223
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32364
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29083
CA-64-LT35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212158
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216117
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09831
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OXRN-0226-SM-2I5EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27519
Parenchyma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.99
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04762
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02047
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841006
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
DE-34-DT75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.502956
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6254
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065347
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2273
Corpus striatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.904
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836509
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32639
AIFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54051
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08425
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7398
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27886
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04707
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
AA-46-GL76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282346
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.164
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19591
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05735
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59171
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.971691
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71688
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94412
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79845
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274418
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07143
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80689
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061723
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.3111
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38578
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050542
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
C17orf107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27304
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06222
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76547
CRCGN015_MCF10A.TP53.M_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17675
SMAD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74283
sarcoplasmic reticulum	GO Cellular Component Annotations 2025	1.0	null
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14833
OB-65-AI50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317829
Cytosolic proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
ARFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94123
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66236
QB-35-FO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.531356
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.893686
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1632
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21913
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22112
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057928
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.193
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.367
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12997
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328614
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40222
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054892
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930183
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.06486
Pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4643
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1678
TBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95161
ZFP36L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28271
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5948
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052579
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.737131
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.9796
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
pallor	MGI Mouse Phenotype Associations 2023	1.0	null
MTHFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89327
CRCGN015_HEPG2_48H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39463
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	1.0	3.12826
Peripheral blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
CYP2A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7242
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87678
hypersensitivity reaction type iv disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.348614
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.1611
hela	HPA Cell Line Gene Expression Profiles	-1.0	-0.957143
T-lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06517
Glycosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Dihydrolipoyl dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.868
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
colo829	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4858
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05166
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96023
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.75
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30575
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10886
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07527
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935802
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15129
SD-69-QA40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.396449
hepatic necrosis	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN008_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4128
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852195
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.38243
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.395
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958186
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07995
Lymphoblastoid cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055064
TWIST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28853
SLC11A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49003
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30012
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328946
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18321
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46235
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69528
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94223
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5786
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.126
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
OB-06-WW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.47134
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843295
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1287
LA-86-XT29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206911
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
RAPGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68867
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57935
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413724
MA-31-VM30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257292
Ventral nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32945
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93431
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.671592
negative regulation of transforming growth factor beta receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925795
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0701
CGAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64727
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37712
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53299
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Agenesis of the corpus callosum with peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
KDM7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34307
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.6
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055375
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
MED23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42893
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01223
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.183
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251933
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
QA-14-AU91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.383278
AA-46-GL76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345182
Dendritic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.395
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04135
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2593
INTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98876
CRCGN015_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13813
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13478
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276427
SFT2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83546
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857652
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.85122
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233995
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061101
hepg2	HPA Cell Line Gene Expression Profiles	1.0	0.908496
CRCGN015_MCF10A_48H:E15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.32292
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964374
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13514
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
ED-33-YZ72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20686
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32224
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18706
SKIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44809
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09221
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859147
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04097
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6857
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
atrophic muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.223853
Fast twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
Pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50359
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRMT61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00914
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
JF-84-QZ64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250058
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.949685
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45569
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.268
MRE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95178
Peripheral ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.146
MARCKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27275
TFPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56228
sarcoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053959
TNFRSF10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99194
JF-84-QZ64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210651
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82539
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09158
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4959
Monocyte_Fetal kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
mda-mb-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227186
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50366
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29764
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058137
PIP4P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55512
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6724
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25524
ZSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73134
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34989
RPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48372
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920643
S0-EE-XMXE_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211571
ADA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17162
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72724
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831405
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380398
edema	MGI Mouse Phenotype Associations 2023	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.611577
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
Prespliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
GPR143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07136
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98905
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6626
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5805
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21263
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.40532
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58113
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.63351
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16952
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83977
gallbladder	HPA Tissue Gene Expression Profiles	-1.0	-0.931394
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Sarcoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.73553
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	0.932249
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.59331
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
Retinal ganglion cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
dilated heart right ventricle	MGI Mouse Phenotype Associations 2023	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13402
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5077
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.5497
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
MAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34966
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563915
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57559
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052481
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938277
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11898
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.21859
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33009
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052815
Cayman type cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41042
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09632
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28413
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82428
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15798
floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.756604
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324149
DE-99-OT37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207486
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82472
ST486	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM203	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2204
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.618359
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
HTR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57928
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44746
Pulmonary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88016
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10255
DSIF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5903
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.51837
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
KC-17-YN77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327205
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8164
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951625
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54701
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853816
BEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36886
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9433
Elongin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52559
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.4486
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2691
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.643666
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67743
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931038
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047801
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87401
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.01231
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11688
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92628
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846102
CRCGN016_MCF10A.TP53.M_24H:H12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36834
t-lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.423054
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944541
LAN-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18025
HeLa-S3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
Collagen type I trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0068
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68669
LDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70549
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894779
POLH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22551
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64313
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03341
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052121
caco-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249977
LGALS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
Split hand-foot malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13658
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058635
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19202
AS3MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76768
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.938465
YB-58-IZ37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.306812
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.472
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6083
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203583
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373369
CRCGN017_MCF10A.WT.HP_24H:K16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0433
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12846
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377156
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33686
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12663
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39451
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.817975
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92966
HD-22-GO73_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328373
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
Hair follicle dermal papilla cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:D10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.22547
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64841
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
BA-39-HG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416633
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.912
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.762377
FOXK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73934
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29127
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00725
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00501
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18007
colonrectum_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.10499
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
Hypopharyngeal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
Tassel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
CRCGN017_MCF10A.WT.HP_24H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.179
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05339
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266809
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27159
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03158
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33595
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75812
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2281
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51212
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13722
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64534
FOXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29679
sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.392629
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7614
balb/3t3clonea31	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.683088
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.268
ND-68-CU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207999
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7735
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38029
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901502
ZNF177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35904
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2123
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.009
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949427
Detroit-562 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26633
pbmc cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215147
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04759
FOXN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4589
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30793
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19707
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68098
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.82338
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62804
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.924085
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HA-50-AT10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231504
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08338
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.36118
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94728
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38745
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19889
Perturb_6606_KD_CMTM6_ERP123354	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.22395
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56337
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59986
FBXW8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69278
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835601
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4954
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.891592
Fast muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264638
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91449
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.77544
MAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63045
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4294
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.668168
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60703
CRCGN016_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58623
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5536
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92764
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49873
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
Myelencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.432
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28185
AC-91-AV48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330825
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06652
SERPINB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98646
C1orf35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33945
oculopharyngeal muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.998236
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1051
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.07665
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5308
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85634
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13779
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05856
Caudate nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.904
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1295
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80273
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373002
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4167
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376803
af1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
CRCGN010_HEPG2_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03965
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901468
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904012
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087938
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875457
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6421
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26255
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73089
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-ETS2_mod_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37544
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5106
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-0.941412
BC-82-PP66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259374
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56611
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.086
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54745
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47725
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336134
CRCGN015_MCF10A.TP53.M_24H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06825
CARMIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51432
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03224
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01125
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054663
DDX3Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62084
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91859
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
POMC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34934
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62056
abnormal muscle physiology	MGI Mouse Phenotype Associations 2023	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.411349
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37717
CC-90-FE70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328044
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89614
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95846
CCDC87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6947
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-1.066
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1532
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46782
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827362
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066614
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896856
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0264
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08292
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
Precatalytic spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70989
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947814
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26925
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828589
ZNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33804
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872581
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859855
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00658
DCAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02689
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20969
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52843
NB-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061828
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.074
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38797
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96055
RMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48836
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6708
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9059
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79059
Buccal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
ASCL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82826
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.6975
AC-51-WE57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334815
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.97
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060859
ZFP90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5192
Flag leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.862289
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3186
PML body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67121
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.06883
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309371
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872765
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.73877
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.76139
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.99229
CYB5R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33693
ME-16-XW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471475
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056241
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.3416
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918171
AD-06-OB47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.338015
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44209
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90967
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12077
DMS-114 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19585
bronchial epithelial cell	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62197
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929282
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17893
KCNC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67102
H3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39774
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04682
Hematopoietic cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
STX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84735
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911155
HC-76-PX74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.475253
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9865
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7464
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15336
bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56498
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.529066
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47334
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21624
RPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93882
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894864
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.35983
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29403
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885283
PRR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22388
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8345
C8orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38236
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45849
GTEX-X8HC-0226-SM-4E3K1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27936
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901081
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.13287
liver hemorrhage	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953423
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220718
Ventral lateral complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.51
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754541
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.900355
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843072
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59208
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.91756
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06378
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6062
ADAM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24819
regulation of activin receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67755
6-phosphofructokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06526
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
Olfactory bulb	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.347
496100435_TCx_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.73115
DC-08-KP05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372999
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935859
GTEX-O5YV-0526-SM-2I5GE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88161
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13069
Perturb_2141_KO_ASCC3_SRP282634	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Psp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
dilated heart left ventricle	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68698
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888984
blood	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0935
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.6317
ELK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42702
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06045
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843983
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57589
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06984
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366381
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44172
CCNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46479
CRCGN015_HEPG2_48H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21115
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9167
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66833
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34634
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87919
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
ADNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04737
AD-09-MD49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.315343
Adrenal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.573
NELFCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36282
t47d	HPA Cell Line Gene Expression Profiles	-1.0	-0.859876
XE-29-LT20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228979
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907697
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72786
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.659797
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31923
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55276
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.912
EHBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71285
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
NENF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83874
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5081
Skeletal muscle satellite cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30165
Endoplasmic reticulum lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.256
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35205
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.6032
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60981
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21444
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.07395
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Oligosaccharyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.999
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47677
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.834375
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24547
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9932
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41578
CRCGN013_HEPG2_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6619
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85171
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905973
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.13789
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58361
APOBEC3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
DSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17428
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17202
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76655
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5632
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35553
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217412
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084021
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.472
YB-58-IZ37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226148
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74371
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09405
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
Respiratory epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.074
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85818
DF-00-BX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333296
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
SCML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
GTEX-WHPG-0626-SM-3NMBD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871988
bronchial epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Pancreatic islet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.34
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10248
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8655
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
SA-31-VB03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241246
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83222
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7573
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36423
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09985
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11101
Replication fork protection complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5503
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860942
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38532
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240148
GTEX-TKQ1-1126-SM-4GIAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860046
YA-44-LW45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219033
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.658071
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09415
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862728
muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.437589
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.842675
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
negative regulation of activin receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11187
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07932
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057155
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211471
u266	HPA Cell Line Gene Expression Profiles	-1.0	-2.3796
29-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79487
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59128
TMEM14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85943
sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.819412
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062921
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8254
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872258
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77553
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059013
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44943
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.735561
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15489
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833174
Leukemia cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041532
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91977
TDRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55834
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9728
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23935
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88505
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
severe acute respiratory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.717232
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42314
UGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98111
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.00835
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0615
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80478
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84741
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66048
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23729
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19402
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44323
ZBTB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31552
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00068
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072462
CPEB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67631
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0258
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50696
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27922
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5999
GPRASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78671
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18278
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972394
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39426
NC-35-BF58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243862
GB-73-QS80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50233
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.5405
Subthalamic nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.307
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883305
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.082492
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42214
Acute lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52277
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04622
Cingulate cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.501
HEATR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96706
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64899
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19745
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.852475
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09325
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890683
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043792
Bronchial epithelial cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.074
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57953
BAX complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4607
FKBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57176
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05672
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050796
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75942
ventricular septal defect	MGI Mouse Phenotype Associations 2023	1.0	null
urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32753
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411648
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81436
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12479
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051194
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2698
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998884
Metallochaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210476_9_v_3_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.223853
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10898
exophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.733406
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7851
Multiple synapse bouton, contacting multiple dendrites	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39569
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.28598
CB-02-XL81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269695
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42239
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62905
GTEX-S33H-0626-SM-2XCBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860079
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06853
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33908
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9318
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299349
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14415
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37557
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.593
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.881806
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63084
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73481
TRERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.673
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22544
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9965
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9473
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964313
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858559
BLZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5888
GTEX-Q734-1826-SM-2I3EL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885875
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26082
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.764962
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15656
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874921
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
BB-28-MC54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288059
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4498
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA-42-YI34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228642
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.913817
Pick's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
FF-46-OR35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.514645
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
TRUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89187
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083886
Diphthamide deficiency syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51731
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.993357
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27485
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32431
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04999
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51635
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0334
esophagus	HPA Tissue Gene Expression Profiles	-1.0	-1.12997
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16038
MBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10047
MRPL58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70361
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Proneural glioma stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91853
TPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62728
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288106
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.3111
LD-48-CY61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.627671
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22257
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80532
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50132
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29843
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.03583
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90528
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15976
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5962
U2-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6892
U2AF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287647
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.628054
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0845
premature death	MGI Mouse Phenotype Associations 2023	1.0	null
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5834
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855756
H1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72244
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22941
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441173
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
myopathy of extraocular muscle	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.9839
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055149
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5931
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84614
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75936
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8771
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45467
BF-00-PE90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209069
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7535
RIGI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11081
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78922
Plant cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13407
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34887
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78291
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
SLC41A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33273
FASLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7054
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057276
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.27976
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61682
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06902
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81306
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3768
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995076
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48808
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.402602
EF-22-PB37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220426
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889562
ADSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74564
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868946
TOR4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69423
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394038
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7204
Medulla oblongata	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.432
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289958
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20066
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99338
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
CRCGN015_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08652
free-living state	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.91135
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71386
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44614
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24603
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051069
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380953
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.671
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56791
496100614_PCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00351
orbital disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.909787
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301217
Globus pallidus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.166
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.28968
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23625
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058103
APCDD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0901
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969335
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29836
AC-38-WM38_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33593
ERBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02293
S0-EE-XMXE_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31496
ZNF681	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25048
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67849
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874655
DCANP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13289
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33109
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24605
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.637
FaDu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6697
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.11627
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11155
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67777
CRCGN017_MCF10A.WT.HP_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2365
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19837
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058426
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057741
BTF3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20399
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67319
CRCGN017_MCF10A.WT.HP_24H:I16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02677
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.516897
Diphthamide deficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.67762
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95405
u138mg	HPA Cell Line Gene Expression Profiles	1.0	2.57063
NCI-H2126 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17643
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94127
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4474
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85308
RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15258
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964036
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7889
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06155
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36976
Mitotic spindle assembly checkpoint MAD1-MAD2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6565
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943512
KC-17-YN77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248915
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33787
SKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56816
PMC8314029-12931_2021_1797_MOESM5_ESM.xlsx-DE_genes_in_ACDMPV-Gene_stable_ID_FOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062206
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22562
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6037
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68173
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03835
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74611
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61987
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0858
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3123
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02393
BPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
CRCGN016_MCF10A.TP53.M_24H:E06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66499
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12141
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957665
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03582
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23398
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05544
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
Parathyroid hormone secreting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8567
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64579
Blood cancer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.685
GTEX-XBED-1326-SM-4AT4F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857974
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.28769
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87012
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02306
SE-91-VW19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207341
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83185
ED-15-OX47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244242
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84817
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43353
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89652
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969531
skmel30	HPA Cell Line Gene Expression Profiles	1.0	1.05856
Nucleus lentiformis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.166
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.912
BE-69-RD44_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40758
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28846
Mitochondrial permeability transition pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.66
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860232
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5483
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21284
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0519
SK-MEL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9696
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71315
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60959
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4451
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940471
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066485
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
HDGFL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45667
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.126
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89968
GTEX-S32W-2026-SM-4AD6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914275
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060565
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871452
Thalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.338
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975255
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38577
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95495
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6906
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.762
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97546
GTEX-XXEK-1426-SM-4BRW1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00628
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318315
HDAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
EF-80-OD07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.463451
perinatal lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944355
HC-18-NB46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220817
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.48092
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62187
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.88884
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
GSE140965_2_v_3_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
VB-89-RG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348672
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7823
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40378
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998665
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	1.40986
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09896
ARL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05959
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28008
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.33909
CRCGN017_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25773
PPFIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66141
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269291
AE-05-CB45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201265
Lymphosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73829
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20678
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235448
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23527
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5905
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91358
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25128
Hypopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749