association	dataset	threshold value	standardized value
ACBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61299
Cutaneous leiomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
PMC4599908-pgen.1005526.s009.xlsx-Table_S8-Overlap_of_FOXO3_direct_targets_from_Eijkelenboom_et_al_with_clusters_R_and_Q_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9578
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12693
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5873
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42225
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59491
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
ACTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59903
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
CCNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46479
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00722
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.884
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
SSNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11002
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16594
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86397
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6997
SAP30L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9444
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21727
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03093
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08819
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
Breast disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.556
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71858
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38062
HSDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34264
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03689
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7992
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Down_REST	Rummagene Transcription Factor Associations 2026	1.0	null
SMYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22957
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6144
Esophagus squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.583
BLCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36107
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28909
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64688
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40986
ZNF177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46399
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16124
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4915
WDR83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87241
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.105
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38598
GSE133516_0_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4607
CYRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55858
ZBTB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65514
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
VPS4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
CCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09899
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
XBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60362
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05381
PDXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99758
chr2_201288529_A_C_b38	GTEx eQTL 2025	1.0	1.82136
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.462
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2263
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
LTC4S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11108
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24261
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0843
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24428
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80697
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53543
AIFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61421
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sporoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.031
Gallic acid (hydrate)_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00572169
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26641
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
outer dense fiber	GO Cellular Component Annotations 2025	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1489
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC39A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71676
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30589
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32542
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4004
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
ZNF219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40769
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3625
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.772
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48183
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CFLAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19794
Cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
RFX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76958
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3211
DPYSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58378
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01644
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94634
HSD3B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27286
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
Breast carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.556
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78087
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27373
KLC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85579
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01791
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70608
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18371
HMGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01056
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94448
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54669
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47813
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69241
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99428
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4084
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45431
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.14946
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38667
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.1
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18578
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01264
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32858
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0169
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75425
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6832
Sperm flagellum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3445
GSE186647,GSE217288_2_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Esophageal cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.583
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46811
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6567
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54806
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54638
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5963
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Melanoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.423
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0106
DCTPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38176
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.1
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FCSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56702
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4643
Skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44036
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57526
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54274
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
FOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17465
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10576
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86847
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36154
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.691
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44215
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49037
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02221
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61431
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83116
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79613
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56428
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5587
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12688
Lymphocyte percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.9
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29081
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3084
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23729
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Gravid adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42172
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98264
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.65
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73834
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94048
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70693
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4055
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3324
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Fer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47363
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87136
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.167
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50274
CAMSAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61598
LGALSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57105
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25044
BCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6993
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
FLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74121
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4084
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17242
GSE135350_3_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16376
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97657
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7336
PMC8530322-pone.0258316.s002.xlsx-GG_776_no-AA_776_no-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62502
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13021
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5225
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7375
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5629
Skin stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3323
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.691
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62178
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69647
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52785
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.691
SRRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29479
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34931
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89008
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03765
Squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.583
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45542
Skin pilomatrix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
IDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46729
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
Lymphoid leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00829
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04603
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60527
Hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18637
chr2_201286440_A_G_b38	GTEx eQTL 2025	1.0	1.69517
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3137
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07204
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5348
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4721
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12959
CENPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82464
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48286
TXNDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41144
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53992
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21444
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76369
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51985
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46574
NDUFA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03598
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48033
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24325
PER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74954
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8966
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1819
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22205
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100399_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37665
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Basal cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63333
DPPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40681
PMC12347849-mmc1.pdf-3-ENSG00000118526_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
KLHL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22185
chr2_201288355_T_G_b38	GTEx eQTL 2025	1.0	2.53406
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45973
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9315
Amyotrophic lateral sclerosis type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.712
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0531
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64174
LGALS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47207
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36727
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
TBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30358
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82019
BRD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59535
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52778
GK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43835
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.442
DPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36374
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46759
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27113
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46286
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54889
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96163
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1191
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71723
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.238
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06772
WWC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24497
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
colo829	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83865
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24697
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52757
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78767
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4958
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57565
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.095
ZNF681	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17998
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5504
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17005
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81242
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3627
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09511
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08939
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5773
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06739
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3894
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34505
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57162
NLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51904
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0604
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7776
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02117
ZNF346	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36459
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8446
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
PRKDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54676
EHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05129
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28812
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03894
ETNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33914
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29913
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0733
Non-melanoma skin cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76515
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51216
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25017
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68283
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.115
Gut granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
PMC4599908-pgen.1005526.s016.xlsx-TableS8-Overlap_of_FOXO3_direct_targets_from_Eijkelenboom_et_al_Molecular_Systems_Biology_2013_with_clusters_R_and_Q_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.935
Hypodermal seam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19544
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66235
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22813
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Basal cell carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7787
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98231
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3511
MYOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97042
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6181
NOL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50559
PKDCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03562
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
CD1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64559
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18577
SLC35A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49488
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29309
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0332
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30643
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70054
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38016
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HIBADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86132
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0715
CYP2D6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17667
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42201
Skin melanoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.423
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22415
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74984
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01755
Polar tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.607
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10464
SLC24A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41991
SMAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18478
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22318
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14408
GSE182680,GSE182683_5_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPP1CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61394
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0193
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1053
chr2_201296039_C_T_b38	GTEx eQTL 2025	1.0	1.08567
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20346
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
X-linked dystonia-parkinsonism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1195
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9813
Squamous cell carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3495
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25949
TOP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35858
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26057
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03523
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24677
DMAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49407
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28079
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20958
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45239
9+2 motile cilium	GO Cellular Component Annotations 2025	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73861
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58384
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37897
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.56965
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57714
ITGB3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09375
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GCSAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43574
Substance abuse	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
TRIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03175
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8198
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85994
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51393
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36333
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3899
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.935
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9452
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50525
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.935
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6816
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8404
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52303
MCM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2945
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7538
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30406
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9768
HELZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5387
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.30127
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47942
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44951
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34118
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69273
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17656
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84479
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
PPCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89705
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34583
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59397
DIDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83883
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7467
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24545
FOXE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39085
ZNF571	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86937
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4458
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39419
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0035
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08784
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81597
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58431
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8884
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62608
Breast cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.556
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30153
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71059
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01315
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4704
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13847
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
HMGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70559
VPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90708
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92002
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.935
B3GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68735
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17404
DST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42859
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08665
SLC66A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08747
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00212
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1596
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60802
TAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80961
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.935
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16545
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3081
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46958
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23298
substance-related disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
TUFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51092
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41343
Youthful appearance (self-reported)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14245
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91827
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6017
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.44928
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
Coelomic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6794
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6937
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
C11orf98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32548
FHIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54986
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6324
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86281
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3774
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1645
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1737
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2765
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16679
Cutaneous squamous cell carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32859
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1358
ARID5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50364
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69858
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11717
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9951
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
HOXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74393
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6302
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6069
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30471
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01686
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
HT-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35247
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7873
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2769
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51384
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
Outer dense fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79322
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4827
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42544
PAPOLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07098
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68006
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02551
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Type I interferon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13284
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
RPMI-7951 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56096
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7777
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03464
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.691
PCDHB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18536
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07778
RECQL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55327
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
RAB3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43274
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75314
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.691
GSE129241_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16866
BTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14127
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.193
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
Esophageal squamous cell carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.23979
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81596
DRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20134
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8835
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74269
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Rectal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
RIC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06821
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80321
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69422
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5483
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3162
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1392
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97691
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2025	1.0	null
Cocaine abuse	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21403
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46058
JPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49506
Arrector pili muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73829
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4568
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49731
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86468
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40963
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9941
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73601
MT-ND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83094
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6506
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75306
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.125
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27656
LAMTOR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55588
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47344
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1592
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6297
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53535
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8352
TMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32482
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3507
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33849
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8304
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80312
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7143
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45158
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61289
DMRTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4486
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77075
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11824
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9839
ZNF131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10552
DNAJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37701
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43355
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64753
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83057
SLC16A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6463
Meibomian cyst	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45501
CHAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96183
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4125
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60441
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53438
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
Skin carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
Keratinocyte cancer (MTAG)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.7699
SYNCRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59459
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10508
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39329
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7509
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5408
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46177
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5863
CFAP126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90657
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38326
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
ABHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5093
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1875
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16347
KDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31034
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8327
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10398
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2911
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.182
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67919
SF3B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64251
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13739
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12482
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2984
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.935
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83411
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3899
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06862
SELENOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45055
GGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13938
H2BK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45489
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07728
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8766
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19146
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5293
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05567
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34849
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
ANAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33777
SLC25A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03983
SYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37168
DBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50411
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58959
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.799
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02898
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00435
FGFR1OP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84381
ARHGAP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58979
chr2_201300114_A_C_b38	GTEx eQTL 2025	1.0	1.416
Triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Arntl	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4118
Thoracic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.556
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73225
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05448
VPS45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55859
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80376
Plateletcrit	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
Thoracic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.556
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
estrogen-receptor negative breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
CD248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31246
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30141
BZW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74832
DPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03948
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.583
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6726
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
ZSCAN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19243
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.583
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96547
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53646
LRRC4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19367
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65092
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5195
Leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09722
Breast cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
PMC7927818-AAC.01755-20-s0002.xlsx-Supplemental_Table_1-Supplemental_Table_1_List_of_significantly_altered_genes_in_MDMs_differentiated_in_the_presence_of_PrEP_FTC_v_No_Drug_TDF_v_No_Drug_FTC_v_TDF_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01127
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7939
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52507
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37615
RAD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9756
CDCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50633
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8927
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11667
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45041
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96034
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60724
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32922
MYL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42482
Chronic lymphocytic leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.418
Basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48955
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0483
CHST7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98877
Follicular stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02173
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92089
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45416
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12728
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37209
Female breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
HSPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32775
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59666
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60777
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47843
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07889
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32642
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
Esophageal carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.583
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25562
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.428
RNF167	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47629
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12934
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02125
ZXDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27003
PIGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81825
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.94
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7365
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11863
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00945
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87761
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.78571
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TWF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50391
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16768
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14681
STRA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8907
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.691
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5044
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4223
DLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6375
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28438
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.067
MRPS18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28162
GOLM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63233
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Coelomocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89321
COL5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78153
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63227
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45229
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80056
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18362
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40134
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4379
CEBPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07274
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11055867-41598_2024_60205_MOESM1_ESM.pdf-18-ESRRG_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33191
PBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29413
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31942
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
B3GNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7156
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
sperm flagellum	GO Cellular Component Annotations 2025	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44295
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76667
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6487
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04598
GSE182680,GSE182683_0_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51042
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
BRCA1-BARD1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24896
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
ZNF576	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06302
chr2_201286716_G_C_b38	GTEx eQTL 2025	1.0	1.01666
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48749
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07507
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51827
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2825
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29573
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37735
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58128
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62131
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08863
GSE213588_9_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40447
Platelet count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.8
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29922
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
PTOV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82067
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7738
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30515
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38653
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44748
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1751
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06852
Neutrophil percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.11549
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24709
Lymphocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.0
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44879
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66118
RAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.48437
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18269
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72621
Lung non-small cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.935
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRCA1-A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.691
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34231
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94459
ZNF775	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37421
Esophageal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.583
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29114
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79191
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29239