association	dataset	threshold value	standardized value
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5501
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73785
maintenance of protein localization in organelle	GO Biological Process Annotations 2025	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.93077
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62788
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.758
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58101
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1329
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9093
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.326
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48326
LDLRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54042
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22233
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2799
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0886
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0625
496100475_TCx_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16287
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80734
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1674
abnormal skin morphology	IMPC Knockout Mouse Phenotypes	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.423
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92898
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6031
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3827
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.8856
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48315
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90845
496100558_PCx_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39574
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2752
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45684
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3115
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25653
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7556
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26936
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51969
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89185
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
ZNF844	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56213
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7407
RAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64977
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9139
GSE233140_0_v_1_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93395
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4826
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4742
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.88
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2348
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6567
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	155.202
VDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73972
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15243
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2621
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3146
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56835
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1212
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8246
PUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83635
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2623
SLC2A4RG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84013
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8669
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.592
GSE126402_4_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100387_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44607
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2661
SLC35A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4217
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
FAM124A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67868
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1906
Alzheimer's disease or fasting glucose levels (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1804
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9335
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22546
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7094
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.6447
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3132
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82376
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21155
496100297_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10348
JMJD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20828
protein localization to endoplasmic reticulum	GO Biological Process Annotations 2025	1.0	null
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sperm-egg recognition	GO Biological Process Annotations 2025	1.0	null
GSE180951_6_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41143
GSE139948_3_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100291_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.31599
MAML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20531
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8714
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3682
496100557_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60849
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5485
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5112
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2463
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1831
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0357
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12536
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231720,GSE231724_3_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61942
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80969
METTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5802
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.0833
11p11 2 copy number variation syndrome 	WikiPathways Pathways 2024	1.0	null
male infertility	IMPC Knockout Mouse Phenotypes	1.0	null
PDCD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14861
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7769
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.4447
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0468
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2509
496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.15046
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86524
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7397
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0425
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8576
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4375
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4014
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64922
ZFP36L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28271
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0203
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2233
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96548
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.668
GSE204832_0_v_1_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8096
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
496100565_FWM_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56445
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35967
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9605
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8662
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6736
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4882
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8541
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59752
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30766
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4153
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94518
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8466
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01609
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74579
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73135
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59519
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.9923
CDK11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19507
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4341
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02295
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96769
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6685
HOXD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61483
GSE101239_3_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80306
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59491
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37548
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11614
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8837
GSE126402_4_v_0_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07707
SPNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5917
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51906
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6187
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4919
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6756
ROBO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13972
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83518
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF764	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26413
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0966
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9167
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41517
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1818
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-348-YY1_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0102
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4318
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43592
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15328
IDH3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69418
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48369
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12753515-Table2.XLSX-G5-specific_down_only_top_500-EGR2_EGR2	Rummagene Transcription Factor Associations 2026	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43939
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5411
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7016
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5209
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
ZNF573	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02291
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9856
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9922
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6509
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.7513
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.481
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6634
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2184
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5465
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85926
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0186
496100591_TCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04021
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.059
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6387
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7154
496100379_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75335
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8059
BMAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6874
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5487
BAG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3655
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56073
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01492
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.91178
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126402_2_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4317
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86138
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09588
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
maintenance of protein localization in endoplasmic reticulum	GO Biological Process Annotations 2025	1.0	null
PPP2R5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06543
RTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48882
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11132
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8668
496100590_FWM_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34486
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77238
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.242
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3354
VSNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2851
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1366
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-NR4A2-sequence_name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94119
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53081
RNPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.587
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64678
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3118
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3619
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0458
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7991
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5237
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46087
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6266
GSE196671_6_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02172