association	dataset	threshold value	standardized value
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.969844
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15671
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259507
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259509
VC-19-YG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.95754
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22219
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37372
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930177
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16174
hsa-miR-4517	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09307
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47603
hsa-miR-3668	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6292
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
ACSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47254
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83009
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KON	COSMIC Cell Line Gene Mutation Profiles	1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25239
Reticulum trabeculare	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EC-GI-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1937	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PEG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40482
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.97649
QA-98-TQ46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00113
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304002
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29404
MAST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37231
Calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.818
GPR89A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92025
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13088
IL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08707
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.802994
GB1	CCLE Cell Line Gene CNV Profiles	1.0	1.51385
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50342
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20742
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55859
SLC29A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29377
L33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45262
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7019
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
SNU13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8138
CAPZB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50344
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06444
Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV504	CCLE Cell Line Gene Expression Profiles	1.0	1.36134
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11614
CD-20-MH57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.745765
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0935
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36122
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45717
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23402
BTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05649
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75387
ISTMES2	CCLE Cell Line Gene CNV Profiles	1.0	1.61295
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC11328671-jitc-12-4-s003.pdf-117-FOXH1_FOXH1	Rummagene Transcription Factor Associations 2026	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.35528
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92223
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977811
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SQ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305168
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11139
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35436
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55718
GSE60217_1_v_11_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.17273
TIGD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38448
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47552
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48413
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49361
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1934
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27871
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
HOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21519
RFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94713
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29553
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
SMAD3-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72365
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12652
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891071
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.23074
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14415
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DQX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37902
Lung adenocarcinoma_LUAD_TCGA-05-4430-01A-02R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18512
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79168
KYSE70	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6554
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85568
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GPRC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82693
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03314
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.971801
SF268	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36122
PER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74267
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378647
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91424
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216363
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2375
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353755
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.018
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43052
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2543
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55058
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834308
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1801
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51668
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38089
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4284
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66236
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8925
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89934
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29147
SLR23	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83655
HAL-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14352
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96052
pretectal nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11382
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21863
Palindromic rheumatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78058
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_6_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4424-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304983
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC88A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12735
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9179
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974324
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04895
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
U343	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13711
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72143
SUZ12	ENCODE Transcription Factor Targets	1.0	null
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67499
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.380272
COLO741	CCLE Cell Line Gene CNV Profiles	1.0	1.87026
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RTCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01286
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865192
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM88	CCLE Cell Line Gene Expression Profiles	1.0	1.47597
REH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5051
NA-30-HS87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.548473
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65995
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59402
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1553
MAGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64712
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984585
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
hsa-miR-559	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
SHPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59092
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301909
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.608967
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7128
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.33137
RE-72-IT14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236338
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31037
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6379
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79379
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7474
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.22609
SERPINB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19324
hsa-miR-4762-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7544
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
NCIH441	CCLE Cell Line Gene Expression Profiles	1.0	1.64153
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54705
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99949
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
TUBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64816
Ankylosing spondylitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-3127-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11952327-media-1.pdf-1-ENSG00000184492_FOXD4L1	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75636
Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.717
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830503
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.694412
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949572
TA-34-CK62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23331
KSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36967
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21128
HUTU80	CCLE Cell Line Gene Expression Profiles	1.0	1.6432
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53727
hsa-miR-4696	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C2BBE1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37156
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29394
GATA4-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15988
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.488955
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7417
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4222
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82428
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-SNU-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21053
SF539	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2661
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.08796
RIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5089
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963792
TE-671 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.136
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6955
AP1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95469
HE-43-BS90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249324
CHTOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24802
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62564
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
CFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35467
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05161
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31978
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
KYSE270	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09033
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
496100525_TCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15522
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.13258
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19022
GSE209973_1_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OV90	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73085
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
TIG-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.647091
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27922
MIA-PACA-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZMYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70065
HCC1143	DepMap CRISPR Gene Dependency	1.0	2.16616
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.48604
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
TMEM158	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96066
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73829
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09549
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79858
FNDC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9268
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82286
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5929
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46303
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
NCIH2452	DepMap CRISPR Gene Dependency	1.0	2.26932
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73603
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86683
GB-94-XG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.538861
FOXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34088
496100284_FWM_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47441
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.02431
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07415
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.37624
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5925
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4662-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.654179
HEY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75274
RPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39621
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55711
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05164
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862593
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
AA-39-BD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.59611
CBFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9917
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04707
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.2423
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TD-91-KV46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207397
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IFT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90672
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83614
CJM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71739
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-59-ZD74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208643
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-2.68049
SUPT1	DepMap CRISPR Gene Dependency	1.0	2.39273
CDYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38166
SRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69066
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.94066
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9417
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AC-93-LT43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.09333
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9498
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93637
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.445534
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9472
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825578
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12479
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268821
NFATC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10041
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52893
KP-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22427
DHRS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60279
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891071
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72448
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.63508
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64402
CARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6871
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07056
COLO783	CCLE Cell Line Gene Expression Profiles	1.0	1.37494
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
OCIP5X	DepMap CRISPR Gene Dependency	1.0	2.18611
POLQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85922
H2731	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23932
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.464931
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39053
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17104
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45203
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.985159
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62509
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0912
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08777
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18805
hsa-miR-4796-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862593
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0686
JHU-022	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356915
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23038
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.736
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86008
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56955
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863799
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5385
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5414
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03241
253J	DepMap CRISPR Gene Dependency	1.0	3.02686
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79922
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
NCIH716	DepMap CRISPR Gene Dependency	1.0	2.29219
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207561
SCC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TULP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00643
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2313287	DepMap CRISPR Gene Dependency	1.0	2.94389
CRYBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00492
UMRC6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.17588
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79085
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72244
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93819
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60409
RERF-GC-1B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC35B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43157
Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU2535	DepMap CRISPR Gene Dependency	1.0	2.19188
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.458
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT144	CCLE Cell Line Gene CNV Profiles	1.0	1.3831
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07901
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35015
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.47
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99982
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33752
KPNSI9S	CCLE Cell Line Gene Expression Profiles	1.0	1.79996
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.20927
RAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24311
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09314
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45529
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6158
COR-L311	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2899
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM2664	CCLE Cell Line Gene CNV Profiles	1.0	2.04739
CFPAC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67226
Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66764
KA-81-AG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.434649
inferior frontal gyrus, triangular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28652
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4556
METTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84647
KP-1N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40767
hsa-miR-4666-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ZNF93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7929
RCC-AB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.51249
Normophosphatemic familial tumoral calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.506287
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1811
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOUAI	DepMap CRISPR Gene Dependency	1.0	2.89306
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92682
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74249
NPIPB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31099
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TOV112D	CCLE Cell Line Gene Expression Profiles	1.0	1.5682
Perisynaptic extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.12
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2132
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.402366
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.881
PMC10794847-mmc6.xlsx-PIAS1_KD_up-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.52386
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.555
KDM5B	ENCODE Transcription Factor Targets	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1553
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89388
UNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75456
ANO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7162
SCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37921
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82568
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49279
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.411856
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87507
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71063
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963792
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Female accessory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20841
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44746
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DTX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20979
SLC2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2517
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.316
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
SUPHD1	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01889
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6743
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70434
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
D-336MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04657
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85478
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26231
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23173
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ATOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20235
ISTMES2	DepMap CRISPR Gene Dependency	1.0	2.52949
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14099
hsa-miR-610	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77381
Acute Myeloid Leukemia_LAML_TCGA-AB-2814-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06397
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.35193
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00742
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11437185-41467_2024_50986_MOESM4_ESM.xlsx-HDSP-KD-RNAseq-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71152
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.25
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9189
GALK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31622
CREST syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80208
Facioscapulohumeral muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
BECKER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29103
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60048
ZNF281	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94004
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.02786
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34926
hsa-miR-4752	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TE11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70035
Kidney Chromophobe_KICH_TCGA-KN-8422-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.451617
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.96283
AA-49-BD04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.599996
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.76225
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06853
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34856
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15227
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.50251
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56069
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3159
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80041
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3781
RA-42-CM42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2077
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93483
RAPGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95265
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.2395
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78559
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
RPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73186
hsa-miR-340	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27871
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06853
GTF2IRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19887
MTRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6867
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42744
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN74	DepMap CRISPR Gene Dependency	1.0	2.30062
GGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10859
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66132
PMC12263605-DataSheet1.pdf-415-LIN54_LIN54	Rummagene Transcription Factor Associations 2026	1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.16401
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MHC class I protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
ZNF99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70835
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56761
HCT116	CCLE Cell Line Gene Expression Profiles	-1.0	-2.97104
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33262
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984585
CE-20-VA70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.34238
NB14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42377
kidney	HPA Tissue Gene Expression Profiles	1.0	2.21462
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89792
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85154
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06385
EW8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90957
hsa-miR-4797-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MV-4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78144
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889861
IM-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.71457
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6914
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90471
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58372
LU-134-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4183
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949572
HUO9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90296
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17917
WDR45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61248
NC-29-PY58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.493629
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90128
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58748
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.555
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.621356
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OV-17R	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
MARVELD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19434
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832996
HULC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
WDR54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3319
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.748993
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GGCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84393
JB-23-ZE86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.48244
U118MG	CCLE Cell Line Gene CNV Profiles	1.0	1.60409
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47282
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12012
MDAMB415	CCLE Cell Line Gene CNV Profiles	-1.0	-2.47765
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37957
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.337099
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8781
Serous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
IGROV1	CCLE Cell Line Gene Expression Profiles	1.0	1.36729
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16174
Lung squamous cell carcinoma_LUSC_TCGA-85-A53L-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.1151
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.522584
hsa-miR-3124-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873305
UMUC9	DepMap CRISPR Gene Dependency	1.0	2.78064
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DFFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03951
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L279	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81735
OSC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ITGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43173
Perturb_1177_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
RC-52-AC88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.5174
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59735
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957505
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-U87MG_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
AC-47-YZ27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257162
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
RXR-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23301
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4437
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266148
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54082
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02519
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27871
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.440793
ED-02-CL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.999011
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97295
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06853
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56885
hsa-miR-410	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-374c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28443
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09243
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7005
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1553
RCC-JF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS-578-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889861
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922617
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
YH-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47612
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357067
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19836
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00272
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZQ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSTZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22583
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63923
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
CB-11-GB40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249013
MTA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73974
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9306
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	1.0	1.38664
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EW-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TD-40-ZR64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263881
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.13001
C4I	DepMap CRISPR Gene Dependency	1.0	2.37894
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987478
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.940288
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78275
L428	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
FD-20-OG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24804
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.25
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64929
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0966
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983244
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHMAC5	DepMap CRISPR Gene Dependency	1.0	2.58479
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.972729
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1563
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219685
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.77679
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84461
SKN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EA-62-MI89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369313
CELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08673
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
EIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13092
SF172	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53515
L33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13006
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLM1	CCLE Cell Line Gene CNV Profiles	1.0	1.41727
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13955
CCNJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64376
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347275
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.906559
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85786
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97753
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03358
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99524
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.66219
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.443
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.345
Histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
ARID4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81512
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.3964
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7337
PIAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SEC23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39361
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
IPAF inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.691
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7519
OSC-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96553
TMEM254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91999
HUH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16096
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30316
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58454
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03358
CAOV-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26177
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B3-01A-12R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
NEC8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15671
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.380148
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99564
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
PMC10863010-media-2.xlsx-ST18-Unnamed_3_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_6_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VC-19-YG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.59244
EDNRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1381
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90643
EC-89-AJ93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206538
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67303
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1591
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8438
OV-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65949
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0363
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29185
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16391
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23053
HT-1197	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Exodeoxyribonuclease VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.229
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
SIRT6	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287184
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8155
CCNI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53154
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77982
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67289
KDM5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40401
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38776
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7551
FAM83E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85374
GSE209533_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54297
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41965
organelle	GO Cellular Component Annotations 2015	1.0	null
SNU5	CCLE Cell Line Gene CNV Profiles	1.0	1.36602
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6517
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34979
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7873
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
UQCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77524
OACM5-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36757
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.747843
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.860665
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
HDLM2	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416705
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.18308
16455954-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior temporal gyrus, left, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11891
ZNF124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75582
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
MELHO	CCLE Cell Line Gene CNV Profiles	1.0	1.64122
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5652
outer SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01835
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37001
TBC1D14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8319
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.835064
Desmoid tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.55439
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
LS180	DepMap CRISPR Gene Dependency	1.0	2.4617
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31806
CHPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76109
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.83865
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.55647
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06946
UBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66564
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7899
GSTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70107
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GF-37-MB64_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231409
KNS-81-FD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09139
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85552
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ADSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23368
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.838497
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.24163
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
OB-17-DQ74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.796632
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4307
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.40687
JA-79-II25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215328
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
hsa-miR-148b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hsa-miR-1276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
SYT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83302
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8856
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56693
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.698299
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.62288
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
KMRC1	CCLE Cell Line Gene Expression Profiles	1.0	1.66967
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52293
hsa-miR-148a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
KCIMOH1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48989
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
CAMSAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
H2795	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS746T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98231
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43313
GDF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32282
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4619
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
Serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41409
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.3521
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.843034
Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CA-48-CT20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330265
JHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03841
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870203
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96479
TP53BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
UMR-106 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3958
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.45062
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-20-VA70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.506238
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19318
MDAMB435S	CCLE Cell Line Gene CNV Profiles	1.0	1.74463
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35949
E2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71752
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35604
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76105
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.88351
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06853
P3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73438
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39569
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42195
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277077
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AC-56-ZV05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.405015
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836347
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21465
XRCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31217
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8059
RA-42-CM42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206861
cingulate gyrus, frontal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.861093
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68416
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34169
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PITPNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.887
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.475049
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88468
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35765
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50203
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95933
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34404
NAXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30545
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50691
Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85547
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26355
CMK115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35789
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAZ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1843
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863799
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02221
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75536
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05207
Calciphylaxis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.717202
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.59866
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61263
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7913
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60566
GA-16-IU17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224112
AD-16-HL96_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22359
ENAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51182
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32813
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.466728
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4344
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.969112
SETD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16358
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06195
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51805
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95531
UPMD1	DepMap CRISPR Gene Dependency	1.0	2.62848
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12028
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77766
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7786
ACSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58383
NCIH28	CCLE Cell Line Gene CNV Profiles	1.0	2.5292
HCC364	CCLE Cell Line Gene Expression Profiles	-1.0	-2.2647
KINGS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G292CLONEA141B1	DepMap CRISPR Gene Dependency	1.0	2.17442
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70784
PANC1	CCLE Cell Line Gene Expression Profiles	1.0	1.4362
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278326
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334972
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234902
PACSIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76624
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	1.49149
WM3772F	DepMap CRISPR Gene Dependency	1.0	2.00072
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87494
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
NCIH1339	CCLE Cell Line Gene Expression Profiles	1.0	1.52801
Lung squamous cell carcinoma_LUSC_TCGA-22-4596-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM133B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71279
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24352
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1322
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863799
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66905
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866569
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15671
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.68457
KGN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RFX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.941
NCIH1975	DepMap CRISPR Gene Dependency	1.0	2.18221
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79558
Perineuronal net	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73601
NZM42	DepMap CRISPR Gene Dependency	1.0	2.4453
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3646	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NB-80-IM48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.638834
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.965118
CA-10-RU23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203002
H3K9me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22257
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28258
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06578
ACBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00683
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.586784
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2322
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7263
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06925
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66679
TLDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03795
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26931
Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4273	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84069
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28613
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
RD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49391
Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SA-03-IQ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212282
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21202
FSCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83757
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2123
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24605
PECAPJ49	DepMap CRISPR Gene Dependency	1.0	2.70558
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56753
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962912
SKMEL1	CCLE Cell Line Gene Expression Profiles	1.0	1.90535
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9537
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29368
TMEM223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58894
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91436
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80735
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60027
BCL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77914
KU812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TUHR4TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39373
Brain Lower Grade Glioma_LGG_TCGA-DB-5280-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7566
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52147
SKGIIIA	DepMap CRISPR Gene Dependency	1.0	2.09522
SEC16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97598
HAGHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48327
PLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.36371
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.662145
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0439
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM2664	DepMap CRISPR Gene Dependency	1.0	2.05877
UB-21-MV06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246565
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.553
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68864
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66148
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
SUZ12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84519
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21659
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.9929
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18343
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58907
FD-20-OG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.71524
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6858
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9735
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987726
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.738798
OB-65-AI50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.863409
GPR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65059
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.939671
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.401144
SKMEL24	CCLE Cell Line Gene CNV Profiles	1.0	1.42486
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60593
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86265
RAB3IL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08385
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50917
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57371
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08927
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83222
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69124
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66683
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.10889
CAKI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03358
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02387
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.32677
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94038
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.14121
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36122
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32187
MOLP-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-4327	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
TBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46002
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850857
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Y-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48916
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30462
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53822
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12636
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16174
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL26L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20401
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862593
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4989
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244433
hsa-miR-188-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
A375SKINCJ1	DepMap CRISPR Gene Dependency	1.0	2.24696
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390026
hsa-miR-4714-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Subjective response to lithium treatment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.609691
ZNF454	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22296
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67989
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1205
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341058
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.501923
skin	HPA Tissue Gene Expression Profiles	1.0	1.14982
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45239
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01819
SW962	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78526
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3676
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7293
A2780	DepMap CRISPR Gene Dependency	1.0	2.77188
HUNS1	DepMap CRISPR Gene Dependency	1.0	2.81248
COL9A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44012
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81752
LB2518-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27719
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.916995
Lung squamous cell carcinoma_LUSC_TCGA-56-6546-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87272
OB-17-DQ74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.13087
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64505
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27319
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50326
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18902
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13119
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07334
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17403
MS751	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95105
UBE2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17068
NF-24-NB76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201401
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49067
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
WM88	DepMap CRISPR Gene Dependency	1.0	2.36481
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chordoid meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6535
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00905
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34311
SUPB15	CCLE Cell Line Gene Expression Profiles	1.0	2.7297
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.888782
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75062
TXNDC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56768
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.879055
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19176
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252222
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75204
KCL22	CCLE Cell Line Gene Expression Profiles	1.0	1.75016
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.53197
EA-18-FP00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293018
BECKER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6172
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.681
TTYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64705
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840609
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
UACC62	CCLE Cell Line Gene CNV Profiles	1.0	2.1612
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260491
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13939
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.400339
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98031
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20545
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COL18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27437
KASUMI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.30947
LMNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5744
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20346
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87484
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3869
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67352
SEMK2	DepMap CRISPR Gene Dependency	1.0	2.18518
TCF4	ChEA Transcription Factor Targets	1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42013
Brain Lower Grade Glioma_LGG_TCGA-DU-6542-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80227
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98647
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TPRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.804
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41965
LPS141	DepMap CRISPR Gene Dependency	1.0	2.14225
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46197
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899553
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935143
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.917
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2143
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74553
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD-26-MB82_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.317226
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TE-441-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNAJC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90933
RAB6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93003
H3K9me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95118
GB-94-XG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.46721
RTKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15073
ZNF224	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62402
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.95846
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.691135
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63853
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3289
PMC10863010-media-2.xlsx-ST18-Unnamed_4_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67314
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51903
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25572
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35034
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82939
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32083
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42096
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18506
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18506
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22128
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GPRASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78671
hsa-miR-1265	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-4695-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RB-55-KL42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270922
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1123
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
HK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26619
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
ZNF341	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70018
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85437
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.06829
TMEM191C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71508
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940927
HOXD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25644
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24412
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293385
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.877105
U031	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9807
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A1HS-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4778-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
YJU2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65728
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.40707
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1049
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
RA-42-CM42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.30754
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25027
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8944
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.841132
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
786-0	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71094
ZNF346	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40442
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2746
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.945603
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33334
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43572
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-101	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3429
NCI-H1688	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H660	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21541
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72839
VMRCRCZ	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90572
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5391
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H522	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318288
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32345
COLO-320-HSR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13426
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51107
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0653
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.408597
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
QB-99-OU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201221
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8646
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
769P	DepMap CRISPR Gene Dependency	1.0	2.0686
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.787
CE-18-ZM38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.23787
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07215
JE-72-KV75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233975
TMEM80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26956
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.435824
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.38102
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52841
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
SP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04168
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7015-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.25187
LRIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84844
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99414
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53379
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43654
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
Sarcoma_SARC_TCGA-HS-A5N9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.23447
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863799
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862668
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.943
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37001
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18732
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.8984
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90108
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47356
HKBMM	DepMap CRISPR Gene Dependency	1.0	2.04847
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11138
OC-21-IP52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340784
EF-74-KW12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264175
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81716
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06772
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862593
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873305
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324261
Chondroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
CTAGE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34157
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59115
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77238
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617
MDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38314
RAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12917
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
MD-91-JM80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232927
JC-02-ZR15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.15719
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08258
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83059
PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
FPGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27672
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100486_PCx_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01245
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8468
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.611974
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214754
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45422
TCCPAN2	DepMap CRISPR Gene Dependency	1.0	2.00651
GATA2	ChEA Transcription Factor Targets	1.0	null
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2087	CCLE Cell Line Gene CNV Profiles	1.0	1.88362
G402	DepMap CRISPR Gene Dependency	1.0	2.16343
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4729	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	1.85021
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56517
PRRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82262
FADU	DepMap CRISPR Gene Dependency	1.0	2.02168
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03709
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03298
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
PGRMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65435
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35569
BB-09-GD09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244333
CAL120	DepMap CRISPR Gene Dependency	1.0	2.92743
Hyperphosphatemic familial tumoral calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.255
AE-37-MC27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.676492
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37404
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979595
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79979
SNX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06579
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20951
NCIH2452	CCLE Cell Line Gene CNV Profiles	1.0	2.14311
MM370	DepMap CRISPR Gene Dependency	1.0	2.23041
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	3.25751
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04365
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1513
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU1076	DepMap CRISPR Gene Dependency	1.0	2.59561
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.315007
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
PPARGC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.783766
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37958
SKRC31	DepMap CRISPR Gene Dependency	1.0	2.07243
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289777
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862593
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56175
SF126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95565
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08408
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.540598
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81457
STYX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78211
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874766
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.45425
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05018
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.480011
ZNF474	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23856
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02779
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IPC298	CCLE Cell Line Gene CNV Profiles	1.0	1.38944
DMS-273	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51651
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68159
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4263
MORCPR	CCLE Cell Line Gene Expression Profiles	1.0	1.55414
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6364
hsa-miR-451b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.547633
SH10TC	CCLE Cell Line Gene CNV Profiles	1.0	1.42071
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07725
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3857
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18854
TP53	ChEA Transcription Factor Targets	1.0	null
MM127	DepMap CRISPR Gene Dependency	1.0	2.88221
IB-56-BR35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271957
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13583
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16783
VCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15045
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77323
Protein FRG2	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30381
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33445
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67091
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280662
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84828
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20202
hsa-miR-128	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20175
CC-09-YG11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24777
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03358
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96777
ZSWIM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05762
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63557
hsa-miR-508-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SNU-182	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM229PE	DepMap CRISPR Gene Dependency	1.0	2.66265
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.03882
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37162
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80986
NPEPPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
HELA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.751068
LASP1NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80581
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.648845
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.615
SLC35F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29728
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4619
CALU-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03467
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0831
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377741
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24625
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2021
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78559
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19304
PCCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44838
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.317701
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51177
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862593
hsa-miR-4252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	2.20255
PLAGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45673
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50086
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.60276
NCI-SNU-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC25A46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83538
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15671
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61466
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15107
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1938
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.573254
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1771
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52113
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02337
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.447837
HF-79-EC41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.504391
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27008
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24155
496100290_PCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79753
SQSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21527
Hip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11952327-media-1.pdf-1-FOXD4L1_FOXD4L1	Rummagene Transcription Factor Associations 2026	1.0	null
G-292_CLONE_A141B1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ubiquitin conjugating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
GOLPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62112
FA-89-PW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.17865
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.75919
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277721
ATXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87128
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48618
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
8505C	DepMap CRISPR Gene Dependency	1.0	2.28713
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21444
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14424
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.898663
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48559
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11926
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8439
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33678
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
GZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07103
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0449
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.2179
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99945
KOPN-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29413
8305C	CCLE Cell Line Gene Expression Profiles	1.0	1.68193
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09419
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251109
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75314
AC-55-XA97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216468
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58974
SPATS2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47929
hsa-miR-4321	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
RL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350262
GA-77-MH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.63422
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6096
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5768
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
RPUSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5014
SMAD3	ChEA Transcription Factor Targets	1.0	null
RAJI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.558609
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28427
C1QL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2152
Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.508424
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904844
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.460014
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66361
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04895
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NB1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71848
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOV112D	DepMap CRISPR Gene Dependency	1.0	2.06495
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16062
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1903
GRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61065
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31138
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10017
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73706
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03467
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3806
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4327
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87132
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32335
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862593
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.496143
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15238
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389226
hsa-miR-300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BC-20-WA90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242365
GABRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52313
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15227
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7191
hsa-miR-152	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
AE-04-SN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243446
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06098
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54914
CCDC51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60792
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05877
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01625
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.60421
hsa-miR-3920	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51T-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4825
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.563
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71567
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76203
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30659
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
NCOA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68929
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61818
BCPAP	CCLE Cell Line Gene Expression Profiles	1.0	1.41647
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2345
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17537
KDM5A	ENCODE Transcription Factor Targets	1.0	null
KYSE520	DepMap CRISPR Gene Dependency	1.0	2.92236
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45387
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14849
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
STAT3	ChEA Transcription Factor Targets	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06458
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.786
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66145
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6906
cellular_component	GO Cellular Component Annotations 2015	1.0	null
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
SMAD4	ChEA Transcription Factor Targets	1.0	null
CYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.67639
HNF4A	ChEA Transcription Factor Targets	1.0	null
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01395
OCI-M1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SAP30	ENCODE Transcription Factor Targets	1.0	null
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27756
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13568
MAP3K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49255
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1246
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261043
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53666
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09952
MERO48A	DepMap CRISPR Gene Dependency	1.0	2.1417
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33109
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.0807
hsa-miR-3200-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
F36P	DepMap CRISPR Gene Dependency	1.0	2.77829
Lung adenocarcinoma_LUAD_TCGA-J2-A4AG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.998223
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.640434
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244166
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2757
VDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73972
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
Lung squamous cell carcinoma_LUSC_TCGA-22-0944-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
NCIH1581	CCLE Cell Line Gene Expression Profiles	1.0	2.97381
DMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51666
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72437
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1033	CCLE Cell Line Gene Expression Profiles	1.0	1.97138
EC-98-KI28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.37624
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67516
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.958886
MLH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72213
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20519
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.81818
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.827698
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.529956
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.42022
synapse-associated extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.119
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69929
RERF-LC-FM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.185
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207858
DAN-G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984585
Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26999
HUCCT1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.203
MUTZ5	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
GC-49-HD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31024
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.886
PPP1CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5798
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00331
hsa-miR-1227	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TP63	ChEA Transcription Factor Targets	1.0	null
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9329
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-3.11639
hsa-miR-4699-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48239
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45939
CHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01259
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3487
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61224
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.973142
Interferon regulatory factor 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90655
3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.404018
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899159
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
SYPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70853
HPAC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8545
KLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54664
ZIC2_01_121	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.72398
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50406
SK-N-DZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rhabdomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
ZCWPW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36283
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34811
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79252
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891071
NE-95-RP07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257049
ACAD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69093
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-1245b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26187
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5633
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59256
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70561
NCI-H2227	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4619
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.666438
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219687
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54274
hsa-miR-4527	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2034
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89016
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2239
hsa-miR-558	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ZNF670	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47766
RFX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76958
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-655	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7472
hsa-miR-587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P32-ISH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42077
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.7986
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45586
Neovascular inflammatory vitreoretinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
CLOCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57464
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.652
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73436
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.767863
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.50139
BLCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63571
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36984
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01025
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307954
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7421
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18079
KDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19603
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87654
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
Facioscapulohumeral muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
Perinucleolar compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41343
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.3426
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60842
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06853
ST486	DepMap CRISPR Gene Dependency	1.0	2.31661
FF-06-MA64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248445
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6698
MM1S	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null