association	dataset	threshold value	standardized value
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.193
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12077596-NIHMS2076735-supplement-2.xlsx-CRflag_RNA_NONO_TFE3-WT_UP-gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243676
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AA-47-MP58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436153
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_2_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15163
GSE211866_2_v_1_usp11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86613
SAP30L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13551
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE237812,GSE237813_4_v_2_hmgb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03247
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.83803
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445412
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.7452
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.803777
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420136
PMC2820592-NIHMS144142-supplement-8.xls-LMS_SAM_3-GENES_HIGHLY_EXPRESSED_IN_GROUP_III_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40499
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	245.013
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.582229
PDE5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90854
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11868
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15273
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3394
C14orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3225
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.527768
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.68703
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	293.42
GOLPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50612
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1817
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4905481-oncotarget-07-11397-s003.xlsx-Pinin_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mononuclear phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3093
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RA-49-ZB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235698
AC-50-FR41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204704
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234063
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50034
PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12077596-NIHMS2076735-supplement-3.xlsx-ATAC_RNA_NONO_TFE3-WT_up-gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1678
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
YT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.796016
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4903
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-431 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435985
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314279
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.2358
PMC2813300-pone.0008960.s011.xls-SOX2_squamous_signature-Gene_Symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-STAT4_mod_STAT4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22282
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.32891
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315859
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5830929-supp_gad.301887.117_Supplemental_Table_S3.xlsx-Sheet1-Downregulated_genes_in_CHD7-KD_and_CHARGE_NE_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17167
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223406
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.41157
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65584
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12642
ED-33-YZ72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327475
ZNF281	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89529
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276725
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-11-FZ23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23488
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
WE-41-YO44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2653
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.15605
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
AP4B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03946
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA-16-ZL71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32224
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-STAT4_mod_STAT4	Rummagene Transcription Factor Associations 2026	1.0	null
PD-11-LM65_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250082
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRKRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33522
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379943
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3333
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Frt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
GAREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47949
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0607
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393569
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451648
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48919
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509461
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08197
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.674392
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10694
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.9069
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08358
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2274
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	722.095
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00433
chr2_26189025_C_T_b38	GTEx eQTL 2025	1.0	1.07329
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02771
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.362
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06103
Mononuclear cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
GSE196699_7_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03798
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52073
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.953419
Marrow cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ND-06-AJ85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261106
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47616
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264758
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90709
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241959
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66414
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.417
AKAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02219
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	453.556
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.583757
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bronchial epithelial cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.41818
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400701
Respiratory epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266388
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.00666
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09916
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37903
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
t60-adrenal_male_1w	MoTrPAC Rat Endurance Exercise Training	1.0	1.5636
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-94-WO47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.398974
GSE201735_3_v_1_cdca7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	435.207
GSE171724_1_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01495
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42288
PMC8698620__F8	PFOCR Pathway Figure Associations 2024	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.922
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360423
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6513
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.880084
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.2917
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33018
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	312.833
USP17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78783
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GD-73-ZF64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241448
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_7_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WA-62-RP29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235133
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.167791
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.306122
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	414.341
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277479
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17711
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5013
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.784
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01352
FA-94-QJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234115
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO3-_-_vs_FOXO3_hMyotubes_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Laryngeal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366301
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7292
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1406
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10763
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460401
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	393.271
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143782_6_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAPK pathway in congenital thyroid cancer	WikiPathways Pathways 2024	1.0	null
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
PMC9437810-mmc6.xlsx-Sheet1-Table_S8_Significant_isoform_switches_unique_to_BE_LGD_TP53_WT_vs_BE_HGD_TP53_MUT_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6557
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114690_2_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4956
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01952
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526016
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2235
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8215
GSE205332_2_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-7-TBX2_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.670363
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6011
EF-73-IP33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237881
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17815
DD-61-DY35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258667
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490316
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.577068
GSE252987_0_v_3_lefamulin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
ITGAV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55627
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201749
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.875246
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.646457
PD-60-FM93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405357
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06369
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4009
GSE228181_0_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.732262
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CB-55-AK76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236325
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69898
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.193
LRRC10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09284
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384721
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6478
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE167546_1_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-COMMON_KD-UP_and_OE-DOWN-86_common_elements_in_kd-up_and_oe-down_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63869
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.04372
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563945
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28218
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233756
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA-68-TC79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31648
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466583
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7585942-mmc5.xlsx-RBM10_OE_downregulated-Supplementary_Table_S5_RBM10-mediated_gene_expression_changes_in_BEAS-2B_and_PC9_cells_Cutoff_P_0_05_log2FoldChange_1_KD_knockdown_OE_overexpression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.193
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.193
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20062
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.755861
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Buccal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
Actin cytoskeleton remodeling and signal transduction 1	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.4404
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8792
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IQGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14358
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243955
aminoacyl-tRNA synthetase multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.186
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Set3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06321
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96991,GSE97117_4_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10061
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_8_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07568
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288828
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56122
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254082
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-15-YU05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260958
LPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32768
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.6034
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24437
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3524
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282265
AF-30-GH67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.753468
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54036
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.474242
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.25
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01077
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.665484
BC-48-WT15_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.442815
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278333
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-SALL2_targets-target_gene_SALL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05357
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221184
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313448
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	2.08261
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217541,GSE217543_3_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6718408-41467_2019_11884_MOESM6_ESM.xlsx-TAD_genes_ST-EPN-RELA-Unnamed_4_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5388
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5803
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0
Endocytic and cytoskeletal regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE246983_1_v_0_cdk12_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.954871
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204818
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0299
PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
DNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16093
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.338
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06884
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dendritic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.189
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	157.016
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9994
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03368
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	531.147
Peripheral blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.189
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0912
GSE193354_0_v_1_saraf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100501_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44593
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	306.68
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19419
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FD-25-KX07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311591
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FE-29-XM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442642
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29012
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272581
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435959
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.145
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14382
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10607
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.88579
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64535
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17342
GCSAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73749
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.614196
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.504469
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
alcohol-related neurodevelopmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3704
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	273.778
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21142
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19054
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372655
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8465
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NC-54-XY91_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256332
HE-16-PO98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33187
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13395
FOXK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73934
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14337
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12283
ZC-12-OO11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.317912
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332668
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_4_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11506
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37727
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19791
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14025
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.193
ACER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3475
No annotation - 1	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234153
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33396
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9968
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9916
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.88784
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49442
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.675212
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC25A45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35711
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225647_1_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EB-28-HP05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203678
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438077
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26887
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6624
AE-06-FY47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232951
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1662
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251056
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chr2_26179725_G_C_b38	GTEx eQTL 2025	1.0	1.32123
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bronchial epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-81-QL64_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315262
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.436
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21279
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96544_1_v_0_mebendazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32079
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57171
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05182
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303037
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09019
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-41-FOXN2_FOXN2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.560281
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0207
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXB9_HOXB9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154961,GSE154963_4_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5072
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214304
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.46436
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_4_v_10_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355059
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18966
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Monocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.996
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37813
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.494492
Fetal alcohol spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14981
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15624
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35864
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27821
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5077
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_11_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448171
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360109
AC-50-JK54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260878
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24497
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214118
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	591.205
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92331
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136340_1_v_2_darunavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00357
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214653
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_5_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72563
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
OE-78-XD40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240248
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2724
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.681949
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21284
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5404
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264666
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CC-03-PW00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253666
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
Meconium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07763
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44892
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31947
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210718_1_v_0_shmt2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214823,GSE214824_4_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453777
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216698
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-80-DI95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314595
GSE254155_1_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fetal alcohol syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GSE97870,GSE97871_1_v_2_ctcf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24224
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278062
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.58313
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.73
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340289
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57815
GSE226983_1_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136869_1_v_0_lpar2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-15-VA57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35766
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.88085
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.39
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293414
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29915
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Supplementary_Table_2B_Contrast_ATF4-def_DMSO_2h_vs_HCT116_DMSO_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59518
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Downregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25535
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8554124-DataSheet2.XLSX-4-RORA_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-81-CAMTA1_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254406
CB-55-AK76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.675963
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10721
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.518528
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10033
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24768
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12401
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36864
Granulosa cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.541747
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TCR signalosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BB-62-MS83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205568
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.651572
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5299
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158320,GSE183351_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310101
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Arntl	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8358
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222752
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52945
WB-82-EL69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244036
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.58405
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32284
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	163.084
BTBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16385
GTEx Heart 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	6.60345
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EID2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63751
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28491
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	311.829
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283532
S0-EE-YNU4_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231541
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210271
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2844
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3513
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DD-74-PJ26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553846
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.1788
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.235
NC-52-HX69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224809
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07971
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14502
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04017
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_3_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7143
PC-68-DU31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283903
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Unnamed_1_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03159
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4811
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	326.241
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5254
Erythroid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.17
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216538_7_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4697
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280077
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CFAP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10204
GSE149035_7_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1659
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12211
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.189
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11589
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274278
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23537
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220689
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146864,GSE146866_2_v_0_fatostatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AE-32-DP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.722362
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30867
GSE128333_3_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252565
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6459557-pbio.3000201.s012.xlsx-Sheet1-FOXD1_FOXD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3474
GSE178714_6_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206123
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE86507,GSE86509_3_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-325-MYCL_MYCL	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0187
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	148.355
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201454
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.96212
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	356.018
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9487
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.874157
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36763
GSE142210_4_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-y_TFEB_KO_LLOMe_VS_WT_LLOMe_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
Buccal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arnt::Hif1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2212
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	487.264
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.84164
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
OB-06-WW76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.611047
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01853
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0143
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77097
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30636
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23445
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233686
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05292
Mlxip	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06648
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66717
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1465
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.05832
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9747
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE181513_0_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.57252
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LB-67-JK40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259399
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.92763
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	1.0	null
GE-77-FY84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328606
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31227
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TB-06-VB30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281331
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.9375
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3002
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07278
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
CE-00-EK89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392494
UNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15075
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null