association	dataset	threshold value	standardized value
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1541
Sperm midpiece	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
RITA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06659
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8072
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68155
ZNF282	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16343
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0205
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal spleen morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83917
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5703
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-742-ENSG00000089775_ZBTB25	Rummagene Transcription Factor Associations 2026	1.0	null
MAPK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16568
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3894
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10266
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11921
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56773
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9265
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23171
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7927
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11919
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44208
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.255
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5175
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
GLOD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19603
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9773
INTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15183
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2319
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66727
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3467
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.549
ANKRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79338
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Immature fraction of reticulocytes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32493
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15116
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1255
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85388
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22098
OXA1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32198
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7848
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01716
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54573
ABHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58712
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07284
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0303
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17573
PTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76067
EPS8L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55221
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8009
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09595
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7435
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03134
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38812
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4091
CISD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93094
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61296
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00178
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65991
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.551
Intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.284
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1567
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7804
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7763
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96072
SELENOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55093
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23365
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.26
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
IGFBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4125
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64777
CYTH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28421
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7214
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2594
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93431
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18913
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01666
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7729
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97813
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08322
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
PNPLA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03426
Nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.284
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17058
TCF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52181
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54488
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91694
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32979
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18154
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60441
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74074
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5137
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4204
enlarged spleen	IMPC Knockout Mouse Phenotypes	1.0	null
HSFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96742
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08497
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50365
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69701
GSE76425_1_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MGAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47455
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
FKBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45617
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08412
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46962
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5461
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60847
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1623
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3585
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67162
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5966
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.829
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87103
COG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9471
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45291
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3205
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61536
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07168
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7711
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51953
GSE126463_4_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBXO27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18858
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06478
RABGGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65945
EYA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5258
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20947
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94443
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47306
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06378
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38584
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01875
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Nearest_Ensembl_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29425
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9459
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67991
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23978
TIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4938
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95403
enlarged thymus	IMPC Knockout Mouse Phenotypes	1.0	null
FIBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27535
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29688
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2698
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9872
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65859
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03307
THEM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01267
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20435
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.0047
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37352
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36296
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49699
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7273
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37185
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.9048
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05035
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33111
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45227
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73997
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36056
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8596
GSE150215_1_v_0_etl4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2594
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3889
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51593
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69207
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95118
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60936
RNF115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13062
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69808
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5019
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4549
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.19886
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35035
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13351
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4997
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14094
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8509
BID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41064
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191105_0_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06213
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86141
GNAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49127
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04999
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24502
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73681
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94682
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94845
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47499
NOL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39986
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62271
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18733
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28303
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
GSE119564_2_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4482
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77204
GSE210655_3_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150671_0_v_3_nptx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01003
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8692
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0108
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.0363
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0874
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
RFWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32484
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9643
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52094
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1075
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74447
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91228
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.084
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4652
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.551
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14426
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.803
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92754
TMEM14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85943
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22253
Prostate epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05748
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1775
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88766
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14021
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42887
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31865
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28644
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79697
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29726
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54725
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.551
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55038
496100399_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2441
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE144838_2_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1428
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67348
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1265
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10812
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3869
ZNF429	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13507
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30918
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18627
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71125
GSE136869_1_v_0_lpar2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.326
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4972
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2584
SMMC-7721 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45773
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8375
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35221
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09726
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25369
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65063
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.551
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82079
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1591
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8802
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3199
abnormal thymus morphology	IMPC Knockout Mouse Phenotypes	1.0	null
MYO1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76691
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1587
GPAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17252
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21713
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88454
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1832
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32087
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32634
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7594
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0251
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9821
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3834
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83796
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07369
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80865
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7465
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1036
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-293-ZBTB25_ZBTB25	Rummagene Transcription Factor Associations 2026	1.0	null
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82456
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4685
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71231
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3401
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3772
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44951
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25468
GAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45959
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95905
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89486
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31665
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4651
PTPN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04111
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6062
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5772
CALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51855
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05002
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24325
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84843
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41884
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8429
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92483
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11917
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3243
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29877
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65872
CCNJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52566
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0068
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04191
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11429
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6261
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54595
GPRASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05444
ZNF534	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18893
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93592
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99568
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5633
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41887
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5099
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82063
MUS81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06364
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01513
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16661
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33074
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	208.915
SYT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07093
Sperm flagellum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48336
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
ADPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66023
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6392
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25123
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30099
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74867
small testis	IMPC Knockout Mouse Phenotypes	1.0	null
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3447
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00546
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50286
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.776
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57231
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26721
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31577
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00599
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7209
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14117
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0996
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.732
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39886
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8181
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26938
SPSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07183
Organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.284
HAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58128
PMC6823153-NIHMS1535502-supplement-3.xlsx-LSD1_SupplData1-Supplementary_Data_1_Potential_common_target_genes_of_LSD1_and_GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NRBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31073
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2626
POLR1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22536
Intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.284
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1128
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2552
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5508
ZNF33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40078
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5069
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08242
CCDC90B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56594
PMC10713402-aging-15-205220-s005.docx-0-RBAK_RBAK	Rummagene Transcription Factor Associations 2026	1.0	null
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07012
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DAOY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07858
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26411
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1458
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4989457-13073_2016_339_MOESM9_ESM.xls-MITF_D1_vs_D10-Gene_id_HUGO_ID_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.33
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81719
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56874
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3818
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80376
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0994
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38639
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32438
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21163
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.3218
SLC25A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3546
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00128
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24116
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05338
ZNF296	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59604
RPLP0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05561
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8719
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68321
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2965
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.683
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4478
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0279
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91669
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75979
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.62405
PINX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49975
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20336
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44551
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30655
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92516
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06605
CDCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10277
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0601
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4047
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88016
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1132
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63395
MAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16736
SYPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3483
KIF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2828
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.284
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4356
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Gene_Name_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86597
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.168
abnormal testis morphology	IMPC Knockout Mouse Phenotypes	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19871
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16889
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53311
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4164
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1661
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36993
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16806
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84058
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5383
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4477
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52149
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83906
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3166
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09108
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23339
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69484
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2841
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
GSE188814,GSE188854_0_v_1_wtap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1737
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10603
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4381
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01808
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33286
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23082
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.39113
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46097
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67006
DUXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89598
CDAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39501
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54154
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4555
HMGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00884
GSE209698_3_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.551
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15189
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17744
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61307
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3671
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78905
GSE186287_1_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40751
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71898
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5529
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08721
RCHY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60952
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07206
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6646
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76875