association	dataset	threshold value	standardized value
SHROOM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14531
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910907
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986333
abdominal symptom	GWASdb SNP-Phenotype Associations	1.0	0.262635
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1431
EHEB	GDSC Cell Line Gene Expression Profiles	1.0	1.68043
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.369
BRD-K98758861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02193
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16431
HCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92884
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.846908
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07841
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05019
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91073
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09108
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7863452-12920_2021_883_MOESM5_ESM.xls-SRG_13_GE2-HCC_vs_17NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50275
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.102677
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.183834
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41168
BRD-K35945596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45172
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63188
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65653
CHPF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00745325
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3444
glycolipid metabolic process	GO Biological Process Annotations 2023	1.0	null
abnormality of male external genitalia	GWASdb SNP-Phenotype Associations	1.0	0.235753
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.92
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52559
glycosphingolipid catabolic process	GO Biological Process Annotations 2015	1.0	null
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
GTEX-XYKS-2226-SM-4E3IU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21395
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97857
testicular cancer	GWASdb SNP-Disease Associations	1.0	0.716372
FLCN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554513
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06332
Lung squamous cell carcinoma_LUSC_TCGA-77-8150-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARCHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58135
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PWWP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7444
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.67759
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.138
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5895
SETD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97153
ESR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61691
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28299
organonitrogen compound catabolic process	GO Biological Process Annotations 2015	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.051554
SEBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42249
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77834
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-11A-12R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1512
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80466
BRD-K45904718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88875
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56032186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19685
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3784
structure	GeneRIF Biological Term Annotations	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BRD-A39996500_radicicol_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDSS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00758076
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14554
15257931-SuppTableA	GeneSigDB Published Gene Signatures	1.0	null
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34811
CRCGN016_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38155
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1185
BRD-K87875370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06125
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49033
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90626
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990221
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54429
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36583698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77677
BRD-K67566344_KU-0063794_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94541
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97803
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52106
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3386
NUGC-3	GDSC Cell Line Gene Expression Profiles	-1.0	-2.406
BRD-K07615667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01824
GRM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67694
BRD-K05584347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13877
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92109
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:B18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1841
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.63287
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.74447
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.594
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94803
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13062
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30237
YY1	ChEA Transcription Factor Targets	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959617
BRD-K95666495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47707
SEPSECS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006367
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86335
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06657
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48095
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63618
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01107
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5181-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02826
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89502
SERPINB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513752
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A80705936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.10944
BRD-K32727528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.92284
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882772
FOXA2	ENCODE Transcription Factor Targets	1.0	null
sphingolipid metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K39985369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.72642
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15572
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC2A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95496
POLR3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00729368
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7622
BRD-K81642886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91987
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.964626
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4866-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMPDH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00341225
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.83794
CDC42BPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1989
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55319
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.01549
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8073
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79345
BRD-A47109850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79551
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43164
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
BRD-K83815133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43333
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
BT-20	GDSC Cell Line Gene Expression Profiles	1.0	1.44301
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMTM7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608912
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09912
GALE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054175
1,4-beta-D-Glucan	HMDB Metabolites of Enzymes	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5097
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5327
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
BRD-K37161540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02302
HCV JFH-1_12Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.4264
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71108
JVM-2	GDSC Cell Line Gene Expression Profiles	1.0	2.2679
glycosphingolipid metabolic process	GO Biological Process Annotations 2025	1.0	null
NFATC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00442919
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00089
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871898
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24654
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.190785
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82354
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885627
BRD-K75206048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31433
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.18096
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841706
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11931
15208663-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
glycosyl compound catabolic process	GO Biological Process Annotations 2025	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0177
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11883
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.948608
PINX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46738
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
LTA4H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00392423
BRD-K85807048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12236
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
FBXL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21048
CXCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447734
TSSK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00839384
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28298
membrane lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
ORAI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597267
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13741
leukemia	GWASdb SNP-Disease Associations	1.0	0.251068
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05043
Fetal Death	CTD Gene-Disease Associations	1.0	1.14747
glycosyl compound catabolic process	GO Biological Process Annotations 2015	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.616892
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00568545
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78984
cyclosporine_homo sapiens_gpl570_gse15935	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
19841744-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30481
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65M-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.069949
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27163
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20744
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69333
BRD-K06117861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.94105
BRD-K37328981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95494
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75721
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832988
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KBTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65355
Fasting glucose	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FS-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hydrophobic	GeneRIF Biological Term Annotations	1.0	null
glycoside catabolic process	GO Biological Process Annotations 2023	1.0	null
PCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630783
BRD-K12884811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.7562
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03707
PRR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67217
BRD-K48557872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14387
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35753
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K21990363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37109
BRD-K99100679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14271
BRD-K83721789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03133
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866294
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58748
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.8266
BRD-K35209334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40756
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19545
Coumaric acid	HMDB Metabolites of Enzymes	1.0	null
SGF29	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605637
BRD-K03821002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21608
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49996
CARD11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586643
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HE-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98526
BRD-K72414522_AZD-5438_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6255
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05975
BRD-A95442017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51322
BRD-K68313733_-666_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68569
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12856
BRD-K26233698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75321
BRD-K22915992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7619
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.983663
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
DYNC2I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05314
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14843
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97602
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81812
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80031
cyanoamino acid metabolism	KEGG Pathways	1.0	null
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18451
POU1F1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685422
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51903
BRD-K54861624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10198
SK-MEL-2	GDSC Cell Line Gene Expression Profiles	1.0	2.11859
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844245
HDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02554
RPS6KA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00779372
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25211
ME1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00493982
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2142
STPG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40182
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90191
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78361
SSB_02_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.61471
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCN4B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517509
PLK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540267
SBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80218
cytosol	GO Cellular Component Annotations 2015	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09054
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956175
BRD-K81110981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.84836
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.32244
GSE133087_3_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5066
HCC366	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75536
BRD-K73523821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48845
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21869
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91655
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.954447
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98184
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53232
BRD-K82935855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0523
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49539
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.53328
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
CD79B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636224
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RBM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54489
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66717
KIT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0207006
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991906
Lung adenocarcinoma_LUAD_TCGA-05-4424-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.73452
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984228
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10256
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6554
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sphingolipid metabolic process	GO Biological Process Annotations 2023	1.0	null
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15876
OVCA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00677111
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57934
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate cancer	GWASdb SNP-Phenotype Associations	1.0	0.616892
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29203
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
Glycoside hydrolase, catalytic domain	InterPro Predicted Protein Domain Annotations	1.0	null
HTR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486213
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0065
DEF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88607
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.21863
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50292
BRD-K76065617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38474
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78468
RT11284	CCLE Cell Line Gene CNV Profiles	1.0	1.40616
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67096761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20851
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70972
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nadide-6091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41485
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01734019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26798
metabolic	GAD High Level Gene-Disease Associations	1.0	0.303208
PML	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00758822
BRD-K58688519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51551
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7351
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79516
CYB5D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96507
RAB5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22401
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3108
ZNF365	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553346
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2143
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16578
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2893
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8588
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31456
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-409-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48037
ZNF679	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20459
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6323
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10606
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
DRD5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00750753
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30757
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89271
BRD-K63446165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4228
positive regulation of exo-alpha-sialidase activity	GO Biological Process Annotations 2023	1.0	null
BRD-K33956247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31306
hydrolase activity, hydrolyzing O-glycosyl compounds	GO Molecular Function Annotations 2023	1.0	null
PRPS1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612383
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JH-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EG-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC35A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4217
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5313
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37535
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0709
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899324
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04192
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19643
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61914
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11879
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97078
RAB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60698
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70855
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACNG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00733485
BRD-K67458784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.65508
BRD-K55606442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53442
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22001
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6046
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10868
MAP7D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88292
PIK3R5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547009
Norwalk Virus_HG23_19515767_GSE15520	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.43328
BRD-K78816149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72172
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36928
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
neoplasm of head and neck	GWASdb SNP-Phenotype Associations	1.0	0.616892
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45963
NCI-H838	GDSC Cell Line Gene Expression Profiles	1.0	1.84303
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.908902
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50831
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3074
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36343
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0912
gaucher	GeneRIF Biological Term Annotations	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19966
REH	CCLE Cell Line Gene Expression Profiles	1.0	1.42795
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1155
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.897177
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12197
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42733
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14817
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983344
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.898753
BRD-K02118124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40069
BRD-K15343038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01966
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42023
BRD-K41341398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71483
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954242
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95875
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69504
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11566
PTGER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542531
Metabolism of lipids and lipoproteins	Reactome Pathways 2014	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
abnormality of the prostate	GWASdb SNP-Phenotype Associations	1.0	0.616892
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2051
BRD-K99805333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93276
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83479
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37852
SLR21	CCLE Cell Line Gene Expression Profiles	1.0	1.3779
hydrolase activity, acting on glycosyl bonds	GO Molecular Function Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27686
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.78803
GALNT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98273
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1699
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55176
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8571
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66661
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2672
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
CJM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50656
BRD-K73969578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01571
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74931
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853979
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06714
CELA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00872282
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40629
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5479
BRD-K76543697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13137
CEP170	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0105935
BRD-K27433204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52021
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20626
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970145
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935305
GAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45959
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98713
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58372
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18596
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58254
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18353
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20108
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90202
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06615
BRD-K76088420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47129
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50846
testicular neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.616892
BRD-K18390106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12854
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	2.06133
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44585
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57976
hsa-miR-34a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54148
COMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88808
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
large intestine cancer	GWASdb SNP-Disease Associations	1.0	0.444863
BRD-K98384558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60654
BRD-K28820796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30815
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3737
BRD-K31372389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.78889
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07299
BRD-K24108193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68898
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30264
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46636
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.82634
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TM4SF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13933
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24052
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
beta-glucoside catabolic process	GO Biological Process Annotations 2023	1.0	null
MS4A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00683013
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.71555
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41985
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04921
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.662
BRD-K47366416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.14434
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75979
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31629
Liver-intrahepatic cholangiocyte	Tabula Sapiens Gene-Cell Associations	1.0	-0.118365
Linamarin	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-640	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3041
NID1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00462676
SLC29A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569375
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
OLIG2	ChEA Transcription Factor Targets	1.0	null
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94354
BRD-K27384243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90737
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7983
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5629-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42145213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51223
496100350_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35402
NDUFV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57724
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74919
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.170473
CRCGN012_HEPG2_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49637
KNSTRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87021
MEGF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74536
BRD-K51153795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31303
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78275
KYSE-150	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57201
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92783
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848153
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72203
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6495
BRD-K20373726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32744
CDHR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00811174
glycosylceramidase activity	GO Molecular Function Annotations 2023	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13811
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1525
liposaccharide metabolic process	GO Biological Process Annotations 2015	1.0	null
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20992
CYP2C8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00427043
PMC12634441-41375_2025_2771_MOESM8_ESM.xlsx-ATACseq-Table_S3_Bulk_ATAC-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUW1-1926-SM-4BOP1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28317
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
IL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572154
NUSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80935
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38745
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85352
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
organonitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3164	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CTCF	ENCODE Transcription Factor Targets	1.0	null
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29435
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95229
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79067
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94775036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03726
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5541
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01692
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.1593
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33588
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.20699
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47109
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93948
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86774
PMC7863452-12920_2021_883_MOESM2_ESM.xls-SRG_23_HCC_vs_17_NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03278
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59602
EW-7	COSMIC Cell Line Gene CNV Profiles	1.0	2.14116
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07372
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96742
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
ASPHD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499013
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01207
CRCGN010_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05595
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84132
LMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64908
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A2-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLVRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2627
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14184
BRD-K71262871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43459
membrane lipid catabolic process	GO Biological Process Annotations 2015	1.0	null
galactosidase activity	GO Molecular Function Annotations 2023	1.0	null
MCMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64259
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74294
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72998
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79261
disease	GWASdb SNP-Disease Associations	1.0	0.056554
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	1.53844
Metabolism of lipids	Reactome Pathways 2024	1.0	null
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973016
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14084
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82994
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20144
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55838
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06442
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28333
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.190401
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
BRD-K20416270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5065
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9304
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37152
SUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50538
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64395
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59446
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951012
BRD-K32406588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64028
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65854
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55289
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09371
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07339
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.860206
BRD-K08799216_pelitinib_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99969
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90241
MAFK	ENCODE Transcription Factor Targets	1.0	null
SZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09165
LIVF001-023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15361
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07307
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885627
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16014
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72455
neoplasm of the breast	GWASdb SNP-Phenotype Associations	1.0	0.616892
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5566-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4742
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22943
TMEM30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50865
BRD-K77273085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67431
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.150028
aglycone	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K48899005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33272
metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K26872015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24452
PMC4572003__F2	PFOCR Pathway Figure Associations 2024	1.0	null
long insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13826
GTEX-S4P3-1226-SM-4AD4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29308
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27091
BRD-K29661539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74434
myopia	GWASdb SNP-Phenotype Associations	1.0	0.439043
HIC1_01_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.2405
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
CERT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473509
GALNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35799
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.900709
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00015
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11965
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987758
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05235
BRD-K19731191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27224
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5353
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44617
Substance Dependence	DisGeNET Gene-Disease Associations	1.0	null
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48085
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oligosaccharide catabolic process	GO Biological Process Annotations 2023	1.0	null
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06027
FASTKD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00770856
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29266
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97062
BRD-K21000135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66821
HAO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00668244
USP34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90361
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59951
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66949
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829518
BRD-K39979888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25019
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10652
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872451
BRD-K51743001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18127
SYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42172
DCHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45654
PKDCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03562
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.102677
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954242
HH	CCLE Cell Line Gene Expression Profiles	1.0	1.40494
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.045208
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94216
fusiform gyrus, right, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843455
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26108
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
DPYD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536724
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97274
PMC6344081-elife-40364-supp5.xlsx-PLZF_peaks_H3K27Ac_unchanged-Unnamed_10_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.477
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2666
H2BC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59098
GABBR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580313
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09221
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41874
TCF4	ChEA Transcription Factor Targets	1.0	null
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82601
neoplasm of the large intestine	GWASdb SNP-Phenotype Associations	1.0	0.381276
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86776
PTGFRN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594303
PPARA_agonist activation_GSE17251_474_human_Isolated hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K44950949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23206
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66312
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5596
BRD-K91548063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12799
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
NCIH838	CCLE Cell Line Gene Expression Profiles	1.0	1.83976
BRD-K76763044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22794
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92089
BRD-K80622725_STK397047_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844245
Acetone cyanohydrin	HMDB Metabolites of Enzymes	1.0	null
glucosidase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96383
SLC6A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00796181
GTEX-NFK9-2026-SM-3LK5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934849
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4946
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53478
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15219
TNK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579062
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971224
BRD-K40175214_torin-1_HS578T_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66409
thoracic cancer	GWASdb SNP-Disease Associations	1.0	0.444863
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42364
SUPT3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77114
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15522
BRD-K39617634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.21739
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50547
BRD-K53343197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62566
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21499
valdecoxib-6408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27524
R-atenolol-4259	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39414
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6839
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2028
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
BRD-K46872340_KUC103672 KUC103672N_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65947
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22515
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42797038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17278
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79258
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96814
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13633
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.64847
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90144
ERICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91864
SCN1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582267
BRD-K93752373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13841
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8757
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45198
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97241
CD22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558718
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82526
hsa-miR-4501	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
FAM20C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506076
MAGT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499546
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55007
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04919
PITPNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00638563
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69129
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71977
BTNL10P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570028
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28533
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827667
HUH-7	COSMIC Cell Line Gene CNV Profiles	1.0	2.14116
BRD-K04886976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11915
PRPS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564153
BRD-K65182930_NVP-AUY922_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P78B-1726-SM-3P5ZV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02917
BDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2887
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.28019
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7765
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67593
SH3BP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587405
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLITRK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9333
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85154
SUMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89857
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15986
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.150028
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87392
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98701
MDFIC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059832
TEAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19585
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976421
BRD-K53094498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31942
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17591
RORC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648866
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70615
abnormality of the male genitalia	GWASdb SNP-Phenotype Associations	1.0	0.31677
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14742
BRD-K98731550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25352
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42498
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91615
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.031876
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A101D	CCLE Cell Line Gene Expression Profiles	1.0	1.35353
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3544
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41369
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.81035
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98568
BRD-A23193246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65686
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.18532
BRD-K08408085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36465
glycoside catabolic process	GO Biological Process Annotations 2015	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.918062
BRD-K38955287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14579
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13048
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879579
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glucosidase activity	GO Molecular Function Annotations 2015	1.0	null
IL3RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547326
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32212
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871898
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88933
RTEL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580129
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21296
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42239
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65105
ZNF839	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6601
acute myeloid leukemia	GWASdb SNP-Disease Associations	1.0	0.716372
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4816
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79105
Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ILDR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531153
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.179
CHRNA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467532
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.51144
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47156
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.060197
BRD-A15086915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27154
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56732
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827667
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2516
FOXP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611161
MLH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72213
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5985
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.69535
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10486
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08781
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35208
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7604
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27189
BRD-K80232129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50093
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16689
carbohydrate catabolic process	GO Biological Process Annotations 2023	1.0	null
ICAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89788
VAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07787
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.9694
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NLRP6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00734049
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60152
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4176
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Tourette's syndrome or obsessive-compulsive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
BRD-K95952081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31791
Adrenal Cushing'S Syndrome	DisGeNET Gene-Disease Associations	1.0	null
ITPKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714509
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37451
Sickle Cell Anemia_Endothelial cell_GSE9877	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.171343
BRD-A01759464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44816
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98647
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34137
PHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51546
glycolipid metabolic process	GO Biological Process Annotations 2015	1.0	null
MJ	CCLE Cell Line Gene Expression Profiles	1.0	2.11985
myopia	GWASdb SNP-Disease Associations	1.0	0.5146
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47898
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
KLHL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68655
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26849
TCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11735
ULK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67725
galactosylceramide catabolic process	GO Biological Process Annotations 2023	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44360367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07484
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00873
glycosphingolipid catabolic process	GO Biological Process Annotations 2023	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2644
CRCGN014_HEPG2_3H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18191
B3GNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59135
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41038
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.609691
BRD-K09416995_LOVASTATIN_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sphingolipid metabolism	Reactome Pathways 2014	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40154
NDUFS6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602655
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02457
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4403
abnormality of the intestine	GWASdb SNP-Phenotype Associations	1.0	0.197909
Childhood Asthma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903193
4-Hydroxymandelonitrile	MW Enzyme Metabolite Associations	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853979
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73484
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55643
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56459
galactosylceramidase activity	GO Molecular Function Annotations 2023	1.0	null
UBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48348
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77265
glycolipid catabolic process	GO Biological Process Annotations 2025	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9122
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959617
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15141
SNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27477
FAAP24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00550728
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29976
SKMEL2	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03107
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.56725
galactolipid catabolic process	GO Biological Process Annotations 2025	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938112
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69418
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43023
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.62225
BRD-K86065375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69993
SMC3	ENCODE Transcription Factor Targets	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910907
H4	CCLE Cell Line Gene CNV Profiles	1.0	2.13366
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4091
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83087
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8957
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.07518
BRD-K27719710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63184
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02975
PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59492
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43668
vestibular nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987933
abnormality of the large intestine	GWASdb SNP-Phenotype Associations	1.0	0.262635
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1489
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37854
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05402890_NCGC00165289-01_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COQ7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96846
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88076
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38576
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19665
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80056
SERPINB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00498549
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.64649
JUND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59694
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64741770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02369
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09054
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49384
BRD-K03812127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53581
ESCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	1.03009
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.997969
Large_Intestine-intestinal tuft cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.117383
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20878
BRD-K14233531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16984
HS729	CCLE Cell Line Gene CNV Profiles	1.0	1.35171
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.107
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37348
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2021
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31478
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.175102
Starch and sucrose metabolism	KEGG Pathways 2026	1.0	null
EGFL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09144
starch and sucrose metabolism	KEGG Pathways	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75881
BRD-K52551495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47257
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PABIR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78785
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
NPRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21108
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13877
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.606962
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3503
intestinal cancer	GWASdb SNP-Disease Associations	1.0	0.444863
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32377
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66951
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13437
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853979
SPNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40605
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35223
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K99319496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48607
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03576
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50207
FOXRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79371
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02828
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
PITPNM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598576
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34879
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.24848
BRD-K36923996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64715
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65379
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541574
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2357
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8346
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
KNS60	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
galactosylceramidase activity	GO Molecular Function Annotations 2025	1.0	null
NUDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92203
SNU410	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94
RFXAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578155
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.093684
CLK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584753
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glucosylceramide catabolic process	GO Biological Process Annotations 2023	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854755
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969394
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.119124
CD248	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517652
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3748
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23425
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6322
C14orf28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37053
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07556
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.69399
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37842
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26018
WWC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24497
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69776
hsa-miR-3668	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21159
lipid catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44377
BRD-K49328571_dasatinib_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6484
OUMS23	CCLE Cell Line Gene Expression Profiles	1.0	1.57929
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36421
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03077
hsa-miR-4766-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.43795
FADS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09092
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55428
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-2.96432
BRD-K86998514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86234
H3C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14025
BRD-K12524159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79816
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60058
hsa-miR-140-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K72967213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12827
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00675723
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74728
Glycosphingolipid metabolism	Reactome Pathways 2014	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92905
prostate neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.616892
CMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16478
SMPDL3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8931
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00468081
18410693-TableS14	GeneSigDB Published Gene Signatures	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47046
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40418
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K42191735_buparlisib_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USP6NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31602
positive regulation of exo-alpha-sialidase activity	GO Biological Process Annotations 2025	1.0	null
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887452
occipito-temporal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.926885
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2729
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64104
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.49407
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904564
CRCGN015_MCF10A.WT.HP_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1138
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39154
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60671
BRD-K16681480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11261
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.949721
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20788
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05581
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0008
glycosyl compound catabolic process	GO Biological Process Annotations 2023	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7078
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.20262
morphological abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.12495
SDC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00738716
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29566
496100360_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30749
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50228
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14571
CD160	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00472507
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5459
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867601
PADI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489732
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
JVM2	CCLE Cell Line Gene Expression Profiles	1.0	3.40796
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872339
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05757
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6391
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90483
ECC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60247
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92349
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7513
BACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79532
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cataract	HuGE Navigator Gene-Phenotype Associations	1.0	null
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K69349031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58641
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41346
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39178
biological_process	GO Biological Process Annotations 2015	1.0	null
BZW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74832
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52967
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00405
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90128
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41392
Cellobiose	HMDB Metabolites of Enzymes	1.0	null
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IL4R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00435737
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
beta-glucosidase activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K73808079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10754
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65937
KCND1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534987
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59827
ZNF366	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58351
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
A101D	GDSC Cell Line Gene Expression Profiles	1.0	1.56576
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71855
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99371
SMARCA4	ChEA Transcription Factor Targets	1.0	null
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92539
BRD-K54686062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.17438
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62171
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5213
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25336
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47837
(2R)-2-Hydroxy-2-methylbutanenitrile	HMDB Metabolites of Enzymes	1.0	null
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.89055
CTCF	MotifMap Predicted Transcription Factor Targets	1.0	null
breast cancer	GWASdb SNP-Disease Associations	1.0	0.716372
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47835
BRD-K51370144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08077
BRD-K90819764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11885
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84519
TRHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558214
PGM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00902561
SW1353	CCLE Cell Line Gene Expression Profiles	1.0	1.67561
POLR2J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65631
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1273
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19129
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3066
ACY3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00824491
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98595
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27728416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04821
glycosylceramide catabolic process	GO Biological Process Annotations 2023	1.0	null
glycosylceramidase activity	GO Molecular Function Annotations 2025	1.0	null
NCIH661	CCLE Cell Line Gene Expression Profiles	1.0	2.41385
BRD-K77634326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61977
Prunasin	HMDB Metabolites of Enzymes	1.0	null
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35882
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09989
BRD-K53335788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33452
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57094
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59776
RAB11FIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08574
TEAD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716515
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906499
Glucose	MW Enzyme Metabolite Associations	1.0	null
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
acute myeloid leukemia	GWASdb SNP-Phenotype Associations	1.0	0.616892
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04192
BRD-K34942615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15127
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945656
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.286244
BRD-K97805186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44462
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855332
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19773
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23744
STOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08361
UFSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6208
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869021
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73557
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
CLEC12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00727626
hsa-miR-4460	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-A46778020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00664
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34942
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45314
KCNN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554596
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45844
KYSE180	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49118
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71491
Substance Abuse Problem	DisGeNET Gene-Disease Associations	1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDH11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611787
TOMM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7393
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66485
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96502
beta-glucosidase activity	GO Molecular Function Annotations 2015	1.0	null
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
beta-glucoside metabolic process	GO Biological Process Annotations 2023	1.0	null
PDLIM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00668684
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09614
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04253
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35064
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35264
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06644
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02457
FEM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40915
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1677
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899448
Alpha-D-Glucose	HMDB Metabolites of Enzymes	1.0	null
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55757
BRD-K48593237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04741
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K47109712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01484
glycoside metabolic process	GO Biological Process Annotations 2025	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37584517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75631
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
diarrhea	GWASdb SNP-Phenotype Associations	1.0	0.616892
beta-galactosidase activity	GO Molecular Function Annotations 2015	1.0	null
DDX19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27055
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76932
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3102
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K55160477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01934
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
beta-glucoside catabolic process	GO Biological Process Annotations 2025	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7383
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	1.71342
vorinostat_homo sapiens_gpl570_gse34880	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26036
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
RABGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72434
PF-01378883-00-6410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7829
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33806
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16584
observed	GeneRIF Biological Term Annotations	1.0	null
Linamarin	MW Enzyme Metabolite Associations	1.0	null
EBF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48589
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28762
cancer	GWASdb SNP-Disease Associations	1.0	0.178622
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80292
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.859435
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51217
BRD-K93483334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87762
Cushing Syndrome	DisGeNET Gene-Disease Associations	1.0	null
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
crystal	GeneRIF Biological Term Annotations	1.0	null
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32434
UBE2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71303
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.59527
rosiglitazone_rattus norvegicus_gpl1355_gds3396	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.756
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
RFK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487818
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96744
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71812
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2823
CXCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52706
BRD-A91461229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.89601
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18948
H4C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66766
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39773
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949126
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-421_ChIP-Seq_H3K9me1_2_AR_differential_expression_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93338495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25694
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994175
ZNF622_02_108	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.57289
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6021
glycosylceramidase activity	GO Molecular Function Annotations 2015	1.0	null
Glycoside hydrolase, family 1, active site	InterPro Predicted Protein Domain Annotations	1.0	null
SLC25A29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24797
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04081
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6262
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24821
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
refractive error	GWASdb SNP-Disease Associations	1.0	0.399173
Recurrent Cushing Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S3XE-1126-SM-4AD4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03688
FHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83137
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
Metabolism	Reactome Pathways 2024	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887498
ALKBH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08783
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2818
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31626
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2534
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	2.26459
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37159
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876993
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57453
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01454
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43429
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944394
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
Necrosis	CTD Gene-Disease Associations	1.0	1.32667
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09354
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
Ankylosing spondylitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
LPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36642
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48521
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31056
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30082
BRD-K27915221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.084
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8462
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945406
TRIM33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555952
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50349
TLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
GTPBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07183
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97628
RB1_KD_GSE50532_592_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962638
oligosaccharide metabolic process	GO Biological Process Annotations 2023	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71019
SIDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25938
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928919
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00360386
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93815
liver	GTEx Tissue Gene Expression Profiles	1.0	1.09029
Amygdalin	HMDB Metabolites of Enzymes	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41681
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8608
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917279
carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86263
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47034
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29342
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34667
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30438
glycoside metabolic process	GO Biological Process Annotations 2023	1.0	null
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38619
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
viral infectious disease	GWASdb SNP-Disease Associations	1.0	0.223774
CREB3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20657
ceramide catabolic process	GO Biological Process Annotations 2015	1.0	null
RCHY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60952
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860084
BRD-K16843478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4521
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20520611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60316
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66439
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930681
hsa-miR-34c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SLC6A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592641
NALM1	CCLE Cell Line Gene Expression Profiles	1.0	1.39254
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58584
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97003
glucosylceramide metabolic process	GO Biological Process Annotations 2025	1.0	null
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
FOXA1	ENCODE Transcription Factor Targets	1.0	null
CD177	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00712987
PIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564537
CDKN2AIPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45969
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.102677
Dhurrin	HMDB Metabolites of Enzymes	1.0	null
POFUT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0082395
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.42
H1-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
PFKL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0112645
BRD-K82674931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29394
BRD-K95763144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28567
BRD-K33371292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25184
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.913886
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03225
BRD-A61304759_tanespimycin_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3354
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24676
GPD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0082496
PDHB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00409619
TP53INP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00658708
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20408
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23441
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1818
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57003
CDK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0030219
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51266
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29681
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971086
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56606
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21342
Gaucher Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
abnormality of the testis	GWASdb SNP-Phenotype Associations	1.0	0.335363
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27219
KMT5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.015489
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
oligosaccharide catabolic process	GO Biological Process Annotations 2025	1.0	null
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10018
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3632
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
BRD-K05222558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2438
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49328571_dasatinib_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72367
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996075
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9166
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12775
BRD-K01643633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02145
FN3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00961343
BRD-K12097074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99018
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33122
TNNI3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590823
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41302
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75712
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.17536
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43745
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.13484
GTEX-O5YT-1426-SM-3MJHC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12551
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03116
Glycoside hydrolase superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29394
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07957
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32308
neoplasm of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.150028
BRD-K39099034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0205
Prunasin	MW Enzyme Metabolite Associations	1.0	null
BRD-K08179047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09794
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15857
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38603
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2573
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31204
BRD-K71799778_BML-259_SW620_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.088919
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
BRD-K18139667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79038
NSD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603858
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73136
BRD-K02419152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81903
oligosaccharide metabolic process	GO Biological Process Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3367-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66675
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9003
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895263
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45128
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.07687
NOXO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523116
BRD-K18391257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33009
FCER1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697215
FAM83F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53553
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6053
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920388
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87959
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77715
CRCGN016_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12791
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
PHF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20959
UTP11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533972
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.281
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58173
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44819
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
glucosylceramidase activity	GO Molecular Function Annotations 2025	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3756
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.906039
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871121
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52666
CCAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31643
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.835388
HOS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45287
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.26888
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.87123
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
BRD-K36096526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14195
BRD-K87524836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19585
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2433
CLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03716
PMC6966574__F4	PFOCR Pathway Figure Associations 2024	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2707
BRD-K51399866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21384
Prostate adenocarcinoma_PRAD_TCGA-FC-7961-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910626
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44287
BRD-K97377031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02484
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16933
Beta-D-Glucose	HMDB Metabolites of Enzymes	1.0	null
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03929
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34839
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78022
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910907
BRD-K72936860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30446
RSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90887
glycosylceramide metabolic process	GO Biological Process Annotations 2023	1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02002
PDILT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513785
GCIY	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58995
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6027
DAGLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518344
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.94544
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926652
ENPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26821
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9457
beta-galactosidase activity	GO Molecular Function Annotations 2023	1.0	null
SNU601	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76081
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48085
19061838-TableS3	GeneSigDB Published Gene Signatures	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00715
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83821
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852912
ZNF620	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
PLPBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00547115
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JB-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
positive regulation of hydrolase activity	GO Biological Process Annotations 2025	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09376
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904397
496100560_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33727
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06123
TCOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05393
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15843
GEM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675671
MTIF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28026
BRD-K44123761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28096
colon cancer	GWASdb SNP-Disease Associations	1.0	0.716372
16818663-Table3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07974
OAZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0043641
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09218
PIH1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88647
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.6052
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943465
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14402
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78813464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38432
abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.090593
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06744
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0397
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00024
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95996
SLC39A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64556
glycosphingolipid catabolic process	GO Biological Process Annotations 2025	1.0	null
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00419
MCTP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00490593
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_9_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
diarrhea	GWASdb SNP-Disease Associations	1.0	0.716372
reported	GeneRIF Biological Term Annotations	1.0	null
CACNA1F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00769465
FCGR2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051783
IFITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60253
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-2.21928
TNNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523909
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78
PRKAR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00494199
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48609
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99287
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03096
BRD-K21547369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47958
OIP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051607
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5657
SI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555928
UBLC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56497
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.298214
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8301
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17253
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1269
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08306
SGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00641176
Substance-Related Disorders	CTD Gene-Disease Associations	1.0	2.88009
GSE135030_11_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68431
SNU601	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93432
MYT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00598383
BRD-K05796780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3002
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48183
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TARDBP_02_116	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.83289
BRD-K07688551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54689
Weight Loss	CTD Gene-Disease Associations	1.0	1.267
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871898
MIER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92521
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35596
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.16148
Fever	DisGeNET Gene-Phenotype Associations	1.0	null
galactosidase activity	GO Molecular Function Annotations 2025	1.0	null
T3M10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38824
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3073
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27495
PMC8034568-HEP4-5-661-s001.docx-2-Supporting_Table_S3_Top_100_differentially_expressed_genes_upon_TEAD4_overexpression_in_Huh7_cells_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941767
BRD-A19037878_trichostatin A_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79199
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03133
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86597
BRD-K35792251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10118
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40497
GTEX-WH7G-1326-SM-4LVMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42484
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21604
C1QB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055101
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01921
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
covalently	GeneRIF Biological Term Annotations	1.0	null
Fatigue	DisGeNET Gene-Phenotype Associations	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.475047
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21211
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC4572003__F2	PFOCR Pathway Figure Associations 2023	1.0	null
SLC22A31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80896
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85291
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21409
BRD-K12107215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.83985
galactosylceramide metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K48540267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28529
hsa-miR-653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K57270624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2756
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.939471
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14957
BRD-K04701596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30971
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11981
MC4R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00781222
PHF5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585659
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972603
RASAL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00440275
BRD-K34405227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02823
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31389
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87183
cis-beta-D-Glucosyl-2-hydroxycinnamate	HMDB Metabolites of Enzymes	1.0	null
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04192
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9119
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21975
SLC9A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59097
GOT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00724899
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH889	CCLE Cell Line Gene CNV Profiles	1.0	1.36068
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3444-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleophile	GeneRIF Biological Term Annotations	1.0	null
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19571
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.25665
ACCMESO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64137
BRD-K03209844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19204
GRIK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006466
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
UGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98975
BRD-K16304302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00092
revealed	GeneRIF Biological Term Annotations	1.0	null
CXCL13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497228
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4829
ZNF582	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16346
BRD-K76068355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20553
KAT6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00374045
hematological	GAD High Level Gene-Disease Associations	1.0	0.293278
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25175
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524337
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00766
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950122
catabolic process	GO Biological Process Annotations 2015	1.0	null
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3725
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CNR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00405392
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
RGS13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636994
ADRA1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00656901
MORN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00897001
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02942
BRD-K54112192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.11043
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.472
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2198
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34065
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12765
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51311
TE6	CCLE Cell Line Gene Expression Profiles	1.0	1.63598
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
MS4A6A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595238
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34989
PMC6966574__F4	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02536
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15986
CDH24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98048
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05893
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33987
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4234
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31247
BRD-K44549496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1467
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.23743
UTS2R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651957
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56029
Malignant Transformation	DisGeNET Gene-Phenotype Associations	1.0	null
METTL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573247
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5034
RUFY4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474379
beta-glucoside metabolic process	GO Biological Process Annotations 2025	1.0	null
BRD-K86797399_pracinostat_HA1E_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
BRD-K05969019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96318
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40354
BRD-K47203692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28359
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
TC-YIK	GDSC Cell Line Gene Expression Profiles	1.0	1.97839
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15428
P2RY2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00958631
Glycoside hydrolase, family 1	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41142
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64051
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88802
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06072
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00577
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47942
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944952
BRD-K99252563_QL-XII-47_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prescription Drug Abuse	DisGeNET Gene-Phenotype Associations	1.0	null
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47025
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3731
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1268
BRD-K08036779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30061
cellular lipid catabolic process	GO Biological Process Annotations 2015	1.0	null
REPS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00626199
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93901
CRCGN015_HEPG2_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02431
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.28845
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.84705
protein stabilization	GO Biological Process Annotations 2023	1.0	null
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.44283
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50498
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37632
beta-galactosidase activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K96154586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08707
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87607
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
RAD21	ENCODE Transcription Factor Targets	1.0	null
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21366
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26587
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17473
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
glycoside metabolic process	GO Biological Process Annotations 2015	1.0	null
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67999
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03841
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5038
BRD-K04155570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32958
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37118
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58456
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49488
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interactions	GeneRIF Biological Term Annotations	1.0	null
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
galactosylceramide metabolic process	GO Biological Process Annotations 2023	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2708
Mandelonitrile	HMDB Metabolites of Enzymes	1.0	null
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22623
CRCGN017_MCF10A.WT.HP_24H:A05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09894
LMNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52991
BRD-K52552873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05317
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15024
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01198
BRD-K87461415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40891
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40365
PPP2R5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01238
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.04797
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40401
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7584-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematologic cancer	GWASdb SNP-Disease Associations	1.0	0.119124
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
BRD-K42918627_GSK-2126458_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849927
OBSCN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509739
TE5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77486
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8343
STAT3_01_84	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.27464
gonadal neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.335363
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84874502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05395
White matter lesion progression (adjusted for white matter lesion burden at baseline)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58739
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.170473
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88274
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
PRKD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00454155
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02103
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20533
NCF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566484
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.57305
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43585
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44551
GTEX-XBED-1526-SM-4AT5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09784
colorectal cancer	GWASdb SNP-Disease Associations	1.0	0.444863
BRD-K75252192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00658
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30542
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1671
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40118
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6452
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626733
BRD-K09779858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16103
BRD-K04395157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49573
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08904
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17553
HSD17B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555381
MITF_01_24	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.84135
Pituitary-Dependent Cushing'S Disease	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1303
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37969
abnormal external genitalia	GWASdb SNP-Phenotype Associations	1.0	0.235753
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06481
SLC31A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70004
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33848
PMCH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00745744
BRD-K45937240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00367
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A43330902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43677
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33347
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50746
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05648
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31016
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4154
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87933
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6488
PMC9041830-ppat.1010464.s009.xlsx-MAGeCK_MLE_output-STAT1-KO-Gene_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8223
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29703
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21072
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.85983
glucosylceramide catabolic process	GO Biological Process Annotations 2025	1.0	null
CDK17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695425
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05235
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.998516
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	2.01069
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0135
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0001
PMC11058205-42003_2024_6202_MOESM6_ESM.xlsx-Data3b_DirectGene_FOXA1-Data3b_Genes_directly_regulated_by_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01482
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47571
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.957303
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58298
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.0419
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31227
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71787
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35034
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10652
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52124
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78938
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5061
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33131
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32632
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	1.82366
ceramide catabolic process	GO Biological Process Annotations 2023	1.0	null
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.102
USP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14418
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4371
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.203
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35659
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11651
GNG12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526574
MMP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10742
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87384
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22435
CRCGN011_HEPG2_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06285
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26136
TMEM89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94709
BCLAF1_02_112	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.54689
GYPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32851
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
substrate	GeneRIF Biological Term Annotations	1.0	null
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54705
BRD-K68300789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58172
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854755
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71858
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66337
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16351
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986218
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4029965__F7	PFOCR Pathway Figure Associations 2024	1.0	null
TUBA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00502546
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59976
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ceramide metabolic process	GO Biological Process Annotations 2015	1.0	null
SYK_druginhibition_154_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.19196
molecular_function	GO Molecular Function Annotations 2015	1.0	null
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.72393
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2377
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98237
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31311
BRD-K55479099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.5178
BRD-A88461048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2184
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56835
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97218
SDHD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562934
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
TM2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5064
IRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41346
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.059175
BRD-K17956418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0719
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38434557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05258
HPGDS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583425
TYMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00472667
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62371
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4705
prostate cancer	GWASdb SNP-Disease Associations	1.0	0.716372
ARID4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81512
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24272
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4521	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45852
glycosylceramide metabolic process	GO Biological Process Annotations 2025	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.466
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79969
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02964
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S12_LF_C1_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4984
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mutant	GeneRIF Biological Term Annotations	1.0	null
BRD-K14780713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38792
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27141
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
intracellular part	GO Cellular Component Annotations 2015	1.0	null
BTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08804
MCF7	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.910682
(S)-4-Hydroxymandelonitrile	HMDB Metabolites of Enzymes	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98406
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44663
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.38095
carbohydrate catabolic process	GO Biological Process Annotations 2025	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98712
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21185
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78957
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07160586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76204
aging	GAD High Level Gene-Disease Associations	1.0	0.293278
GPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11185
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07276
STMN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565219
Serum metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.6699
BRD-K22797212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02755
PATU8902	CCLE Cell Line Gene CNV Profiles	1.0	1.89604
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34851
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92371
GH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0121803
Sodium	HMDB Metabolites of Enzymes	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9142
NCIH358	CCLE Cell Line Gene Expression Profiles	1.0	1.75451
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39557
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.18932
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32838
TLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43821
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8061
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52875
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50434315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33909
neoplasm of the genitourinary tract	GWASdb SNP-Phenotype Associations	1.0	0.183834
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58792
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49129
GTEX-XGQ4-1226-SM-4AT67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852025
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20835
UST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8632
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02457
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08677
Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis	DisGeNET Gene-Disease Associations	1.0	null
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12779
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00349
Lotaustralin	HMDB Metabolites of Enzymes	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
type	GeneRIF Biological Term Annotations	1.0	null
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31767
ERAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35946
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07997
BRD-K82506716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1672
BRD-K34206995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29288
BRD-K46994278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02238
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32265
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82304
GLRA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623215
SLC6A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00544575
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03952
hsa-miR-449b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39658
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8292
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06003
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98944347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55212
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39681
CDKN2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00660971
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8218
Granulomatosis With Polyangiitis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K05417183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13584
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.44358
BRD-K92991072_PAC 1_OV7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8089
GLOD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05092
Sphingolipid metabolism	Reactome Pathways 2024	1.0	null
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12926
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24418
hand, foot and mouth disease	GWASdb SNP-Disease Associations	1.0	0.716372
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80815
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17924
PXK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00761265
Lymph_Node-plasmacytoid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.11902
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4735-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
19061838-TableS5	GeneSigDB Published Gene Signatures	1.0	null
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.46968
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of male internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.616892
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0442
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32853
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03444
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13583
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0593
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63014
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H661	GDSC Cell Line Gene Expression Profiles	1.0	2.07145
hsa-miR-4795-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.19229
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary metabolite modules (eigenmetabolites) in chronic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.9699
NDUFB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554771
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90242
TMEM63A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31952
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96272
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77852
DSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16312
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96266
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9888
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76867
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0833
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18125
postcentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832782
PIFO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66907
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39179
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29405
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2748
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70764
PDXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5207
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52812
beta-glucosidase activity	GO Molecular Function Annotations 2023	1.0	null
PRKCSH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCNMA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00605453
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17748
myeloid leukemia	GWASdb SNP-Disease Associations	1.0	0.444863
ABHD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0047682
BRD-K47887272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3011
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cellobiose	MW Enzyme Metabolite Associations	1.0	null
BRD-A04618830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.35122
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08366
BRD-K00463125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01347
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.31826
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90049800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5766
BRD-K48782834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12887
L3MBTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7246
BRD-K26122955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63093
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.081144
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12813
BRD-K06002536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22911
glycoside catabolic process	GO Biological Process Annotations 2025	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.56702
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151612_0_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44994
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41291
moiety	GeneRIF Biological Term Annotations	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47477
CA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00670767
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.36504
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34543
TMEM98	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00659008
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
SW900	CCLE Cell Line Gene CNV Profiles	1.0	2.20996
UCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92284
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73595
BRD-K31230200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13282
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14796
IL12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067839
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	148.095
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78394
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6995
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985502
COG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057772
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49275
PMC5578490-pgen.1006879.s020.xlsx-ETV1_ChiP_pks_tags_txt-Gene_Name_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85943445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36294
BRD-A75954196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16818
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78704
Vasculature-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.11902
BRD-K46121327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16041
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14771
RBIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58344
C18orf32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51478
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4753-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PKHD1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600168
IP6K3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00842399
cellular lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946368
KRAS.LUNG_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98494
leukemia	GWASdb SNP-Phenotype Associations	1.0	0.262635
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60968
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6438
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20819
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42862
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5XZ-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33409
RECQL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00547909
BRD-K23503923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.00488
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.865453
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24826
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00715
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12932
protein stabilization	GO Biological Process Annotations 2025	1.0	null
paracentral lobule, anterior part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835957
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08497
POU4F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62541
Prostate adenocarcinoma_PRAD_TCGA-EJ-5532-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0050683
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACSM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56222
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9557
ADORA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539968
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1632
CLEC10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00842449
BEN	CCLE Cell Line Gene Expression Profiles	1.0	2.59741
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1534
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8754
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
CRCGN016_MCF10A.TP53.M_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2354
glycosyl compound metabolic process	GO Biological Process Annotations 2015	1.0	null
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of refraction	GWASdb SNP-Phenotype Associations	1.0	0.348868
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7186
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
BRD-K81418486_vorinostat_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41287744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40999
MS4A4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00684597
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5111
Cystic Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80264
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47641
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28556
MAMSTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530523
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12132
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01579
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89232
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4405
BRD-K13938991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01048
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01449
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38429
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
BRD-K65766198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24276
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90527
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
positioning	GeneRIF Biological Term Annotations	1.0	null
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10388
ZR75_1	BioGPS Cell Line Gene Expression Profiles	1.0	0.847324
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60519
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.6623
REH	GDSC Cell Line Gene Expression Profiles	1.0	2.52372
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
LN215	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71823
hydrolase activity, hydrolyzing O-glycosyl compounds	GO Molecular Function Annotations 2025	1.0	null
PRKAR2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00624426
BRD-K30217326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70173
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11899_KD_SRC1_SRP108577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.9197
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46074482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47581
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT1376	CCLE Cell Line Gene Expression Profiles	1.0	1.52821
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K52123365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.70092
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
glycosylceramide metabolic process	GO Biological Process Annotations 2015	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50163
DANG	CCLE Cell Line Gene Expression Profiles	1.0	1.54581
ITGA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00687542
BRD-K48294384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53961
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94621
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81793
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09614
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79212
SLC25A12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608657
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-203_ChIP-Seq_H3K9me1_2_AR_differential_down_regulation_upon_KDM3A_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.142278
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857421
MYBBP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00384371
BRD-K96893659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03596
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07434
covalent	GeneRIF Biological Term Annotations	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16237
PLXNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00828322
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83764
phenylpropanoid biosynthesis	KEGG Pathways	1.0	null
IFI27L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96322
BRD-K71566411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0883
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5727
BRD-K85401814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10033
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94093
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1996
CHMP2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00947142
BRD-K05137000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08102
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02496
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09054
TMEM178A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
reproductive organ cancer	GWASdb SNP-Disease Associations	1.0	0.350583
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66503
BRD-K37774987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15372
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.865307
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00474
AURKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00820796
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.48776
Lung adenocarcinoma_LUAD_TCGA-69-8254-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5018
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53423
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5949
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73872184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80502
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03896
PMC4029965__F7	PFOCR Pathway Figure Associations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913882
IGFBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47298
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
ANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0751
SYK_druginhibition_153_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.14589
Eye-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.11902
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SYK_druginhibition_152_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.96049
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03709
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16424
galactolipid catabolic process	GO Biological Process Annotations 2023	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.920231
TMPRSS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583816
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45735
HGH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4131
BRD-K95588139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03327
BRD-K24680618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47396
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76732
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4909
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31721
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
UCKL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00413761
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCAF12L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05593
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49627
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85977570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08607
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
AIFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61421
CKS1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00785832
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7452
POLR2A	ENCODE Transcription Factor Targets	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.95022
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34396
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3809
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37632
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2843
GUCY1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495421
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8295
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59147
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3059
OAZ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559022
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
NCIH2110	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49237
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07422
eye disease	GWASdb SNP-Disease Associations	1.0	0.093684
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6418
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
BRD-K39131701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.43342
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16273
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6385
COMMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5866
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	2.0168
SRSF7_02_02	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.41504
haplotypes	GeneRIF Biological Term Annotations	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.548
bound	GeneRIF Biological Term Annotations	1.0	null
HSD3B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533038
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9784
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21464
breast carcinoma	GWASdb SNP-Phenotype Associations	1.0	0.616892
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
BRD-K39460811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51812
cellular process	GO Biological Process Annotations 2015	1.0	null
dominate	GeneRIF Biological Term Annotations	1.0	null
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56336
BRD-A43135847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05425
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1828
BRD-K13350372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86124
BRD-K47217000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40981
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52449
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05753
ALPG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00741176
BRD-K21450593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8691
IGDCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41634
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57016
hsa-miR-522	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69393
CRCGN015_HEPG2_48H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23646
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0835
Lung adenocarcinoma_LUAD_TCGA-97-7941-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35521
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3962
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14241
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38954
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carbohydrate derivative metabolic process	GO Biological Process Annotations 2015	1.0	null
TUBG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00684143
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate	GeneRIF Biological Term Annotations	1.0	null
SERPINH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70129
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02533
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08429
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45168
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12959
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43058
hsa-miR-449a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2438
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78733
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12714
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24418
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10208
PRKAA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00447224
BRD-A57762296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74175
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63597
MCF7_CUDC-907_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00537788
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
PKIB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483199
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3089
RT112	CCLE Cell Line Gene CNV Profiles	1.0	1.81719
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61678
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09157
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10361
gastrointestinal system cancer	GWASdb SNP-Disease Associations	1.0	0.134079
PDPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20661
BRD-K88189489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5315
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6165
BRD-K28216304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07646
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
P2RY13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658633
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92562
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1018
BRD-K27539817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08872
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39215
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12852
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20018
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966523
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01496
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19601
TPBGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29805
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29408
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10801
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954242
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12595
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82258
glycosphingolipid metabolic process	GO Biological Process Annotations 2023	1.0	null
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15058
acute leukemia	GWASdb SNP-Phenotype Associations	1.0	0.381276
MMP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17215
BRD-K75065750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56242
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49886
Lung squamous cell carcinoma_LUSC_TCGA-46-3769-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3357-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITGAE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00407699
abnormality of the breast	GWASdb SNP-Phenotype Associations	1.0	0.381276
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2394
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51256
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17176
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-11A-12R-A26B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH5	CCLE Cell Line Gene Expression Profiles	1.0	1.86645
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06617
manifestation	GeneRIF Biological Term Annotations	1.0	null
VAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32708
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33261
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5099
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.66999
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
OR2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633482
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67593
BBX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43136
Cancer of thyroid_Thyroid_GSE5364	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.34322
galactosidase activity	GO Molecular Function Annotations 2015	1.0	null
hydrolase activity, hydrolyzing o-glycosyl compounds	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5029-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPSTI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619761
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61602
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46907
H2BC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586533
FBXO34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85773
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868728
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21749
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02931
HOXC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50774
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6815
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0293
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.57126
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-260_ChIP-Seq_H3K9me1_2_AR_differential_down_regulation_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2365
KRAS.300_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4258
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22211
NCI-H358	GDSC Cell Line Gene Expression Profiles	1.0	1.52711
PICALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71893
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HLCS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620982
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00628
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INSRR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00631031
PARD6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02729
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25901
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9852
Gaucher Disease	DisGeNET Gene-Disease Associations	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3699
Rosacea symptom severity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11811
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HuH-7	GDSC Cell Line Gene Expression Profiles	1.0	1.7009
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993899
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7542
D-Glucose	HMDB Metabolites of Enzymes	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.486
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62204
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44717
CLIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67258
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
2-Hydroxy-2-phenylacetonitrile	MW Enzyme Metabolite Associations	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.812317
Organic Mental Disorders, Substance-Induced	DisGeNET Gene-Disease Associations	1.0	null
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69124
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.14296
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1304
BRD-K87990170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13736
RDX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0079694
SHANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40561
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80036
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
HEP3B217	CCLE Cell Line Gene CNV Profiles	1.0	1.43236
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69865
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54632
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43164
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2107
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57296
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
KCNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593963
risedronate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20325
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78729
B9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27574
ZNF738	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74262
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.26359
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63935
glucosylceramidase activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969168
hsa-miR-4717-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
positive regulation of hydrolase activity	GO Biological Process Annotations 2023	1.0	null
BRD-K66963756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59717
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93574
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21263
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18793
APPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92487
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69619
PHTF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00796613
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10596
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecule	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66308
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27769
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
PAQR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06637
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	3.875
RNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7077
SFXN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496205
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42631
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
BRD-K42271016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04007
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36841
BRD-K52136059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0169
VDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9268
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
NDUFB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00494691
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38088
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	2.45703
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2306
single-organism process	GO Biological Process Annotations 2015	1.0	null
head and neck cancer	GWASdb SNP-Disease Associations	1.0	0.716372
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87948
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77621
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.45648
Prostate adenocarcinoma_PRAD_TCGA-J4-A83L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835521
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958609
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865389
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80322
TMEM198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99468
KIFBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42997
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCLY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585487
GLTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564288
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42339
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5692
LIG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053159
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
single-organism catabolic process	GO Biological Process Annotations 2015	1.0	null
SNUC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56178
BRD-K80359388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00227
glucosidase activity	GO Molecular Function Annotations 2023	1.0	null
C32	GDSC Cell Line Gene Expression Profiles	-1.0	-2.0456
BRD-K46291400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45707
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21072
MS4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762181
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38866
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7J9-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKR1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08115
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.69195
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1554
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15846
GBA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00672665
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05034
BCAN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569378
SNUC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47119
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33418
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5208
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954242
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41731186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53358
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15098
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74459
BRD-K20906316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33482
carbohydrate derivative catabolic process	GO Biological Process Annotations 2015	1.0	null
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959617
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21101
SH2D2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01494
BRD-K97869597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2129
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3303
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17226
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4099-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00950228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08387
ZNF471	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49761
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30564
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36342
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.3795
GRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556975
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.969439
BRD-K76353834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.10577
BRD-K41322154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05444
SERP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82434
Metabolism	Reactome Pathways 2014	1.0	null
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64148
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
Manganese levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
FPGT-TNNI3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00474282
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959029
BRD-K44421266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1365
GTPBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587869
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847606
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26581
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98647
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.15511
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21342
ALAS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00437584
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.8692
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6802
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
Anti-saccade response	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74799
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.986465
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94434
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13811
HOXA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70854
RINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90885
Atrophy	CTD Gene-Disease Associations	1.0	1.43428
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05796
SLC15A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653403
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30401
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6153
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15257931-SuppTableD	GeneSigDB Published Gene Signatures	1.0	null
FBRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82069
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18616
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65239
GBP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594119
CRCGN016_MCF10A.WT.HP_24H:L24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25895
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00544
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04407
BRD-K20023110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20438
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53051
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.90733
ECEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.878
BRD-K90858591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18588
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03441
BRD-K57382977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.71401
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
SIK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00448041
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43944
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910526
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23271
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18894
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69013
TSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97138361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47614
GSE216043_10_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6358
neoplasm of the colon	GWASdb SNP-Phenotype Associations	1.0	0.616892
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871898
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12615
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06858
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1857
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cortisol Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67249
MATK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588987
NCIH358	CCLE Cell Line Gene CNV Profiles	1.0	1.43572
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52515
BRD-K23831817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64808
BRD-K91766181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02112
SNU1033	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90246
SLC47A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513042
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08294
BRD-K60631127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12035
ceramide catabolic process	GO Biological Process Annotations 2025	1.0	null
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28511
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6983
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42607
C12orf29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86576
sphingolipid catabolic process	GO Biological Process Annotations 2015	1.0	null
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90182
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
NCIH1944	CCLE Cell Line Gene Expression Profiles	1.0	1.47694
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05606
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6072
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73198
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03256
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983813
Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16171
EFR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53318
Glycosphingolipid metabolism	Reactome Pathways 2024	1.0	null
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54134
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43654
paracentral lobule, anterior part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16507
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91323
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929036
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25459
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28153
ABTB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559913
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.3184
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04343
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90742
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42165
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53703
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0301
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9173
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1059
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.07
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62163
SCML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.73542
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8046
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2123
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858833
HNRNPLL_02_125	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.91886
Lung adenocarcinoma_LUAD_TCGA-50-6673-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68429
West Nile Fever	DisGeNET Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.08736
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920298
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971447
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26083
BRD-K82198647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05295
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3906
SAMD4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32864
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07078
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormal internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.159413
BRD-A02927672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72452
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09054
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853616
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EI-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46056750_AZD-7762_HS578T_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
SFT2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06281
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83261
pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.572129
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17438
BRD-K91810283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52749
BRD-A22032524_AMLODIPINE BESYLATE_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02708799_GSK-1059615_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19649
BRD-K66551929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64956
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30711
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55468
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1628
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17722
regulation of exo-alpha-sialidase activity	GO Biological Process Annotations 2023	1.0	null
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
LPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584998
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6828
ZIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13596
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67732
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48697
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1701
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23408
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96362
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.33887
colon cancer	GWASdb SNP-Phenotype Associations	1.0	0.616892
BRD-K76515685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62762
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2113
MTMR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45865
Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K19702946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19667
abnormal eye physiology	GWASdb SNP-Phenotype Associations	1.0	0.179645
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35896
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.1189
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
glycosphingolipid metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
inner SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931135
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51731
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891511
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33928
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.297658
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.2703
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71742
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13726
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18632
RB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537476
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973197
TPSAB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0085039
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SETD1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00691616
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39326
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
lung cancer	GWASdb SNP-Disease Associations	1.0	0.716372
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8515-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL9L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66214
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21156
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30642
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51015
INTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33066
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19116
BRD-K49875070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19916
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53819
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943025
BRD-K22789469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27705
BRD-K02201521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13795
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4234
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17034
BRD-K32759631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02543
BIRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73755
PMC10260405-41588_2023_1409_MOESM6_ESM.xlsx-ST12-Supplementary_Table_12_Most_likely_causal_genes_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A3L1-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-1326-SM-48U1X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992337
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1275
BST2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00577951
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TNFSF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633853
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.5861
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902137
NBAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514631
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988099
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.87983
Lung squamous cell carcinoma_LUSC_TCGA-60-2711-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92431275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78264
CALCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569858
PMC7863452-12920_2021_883_MOESM6_ESM.xls-SRG_13_GE2-HCC_vs_10_GE1-HCC-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Water	HMDB Metabolites of Enzymes	1.0	null
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.11325
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.28621
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44878
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825266
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.0126
PPP2R2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16122
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94801143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55916
glucose	GeneRIF Biological Term Annotations	1.0	null
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20536
CRCGN015_HEPG2_48H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13236
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38577
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8415
BRD-K17233342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00628
TDRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69043
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67593
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15206
PYCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627454
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68082
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14889
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4874-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4684-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.45304
BRD-K94145457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16371
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00435
PIM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583811
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22465
NOX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00643846
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28203
NDUFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20536
NCIH1339	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59175
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06342
GABRD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607737
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
severity	GeneRIF Biological Term Annotations	1.0	null
GTF2H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4971
BRD-K06997715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27622
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78293
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47735
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44674
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897224
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29775
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19893
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6151
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60716
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63834
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.52802
BRD-K53547009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7019
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01429
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug Habituation	DisGeNET Gene-Phenotype Associations	1.0	null
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20343
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956333
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9076
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
SEC61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53421
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97731
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04074
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.190401
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBMX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40668
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02981
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6268
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20375
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46573
BRD-K10435664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02777
GNAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525785
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40107
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76551
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17476
BRD-K30318008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29622
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970201
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64683
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12795
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95105
TRAPPC13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00483813
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06333
BRD-M56188090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43631
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55511
glycolipid catabolic process	GO Biological Process Annotations 2015	1.0	null
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
USP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26617
MTFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73606
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24734706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48177
BRD-K47031124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21434
HAPSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53655
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90457
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05381
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.054035
glycosylceramide catabolic process	GO Biological Process Annotations 2025	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.977668
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4356
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65976
BRD-A19962819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01605
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.61268
KDM5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29246
FOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47277
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45891
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5806
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08569
BRD-K72932441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37067
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36153
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75981
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77395
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21409
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57473
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54262
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09287
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.78425
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57104
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99431
PDCD1LG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0068023
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glycosphingolipid catabolism	Reactome Pathways 2024	1.0	null
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10115
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50816
BRD-K45609222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24535
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34365
homology	GeneRIF Biological Term Annotations	1.0	null
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15309
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55424
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S8-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K51640940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55186
EHEB	CCLE Cell Line Gene Expression Profiles	1.0	1.8432
PIK3C2G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00415092
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30918
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
hsa-miR-2681	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0142
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926248
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16792
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11292
BRD-K73285375_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K36493118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52554
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	3.26448
FAM20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84517
CHST10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60999
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71508
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.54574
BT20	CCLE Cell Line Gene Expression Profiles	1.0	1.4978
Hypocortisolism Secondary To Another Disorder	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7413-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65879
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
CAMK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00659725
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6073
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48221699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06097
BRD-K07300437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35756
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871252
BRD-K81418486_vorinostat_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRMT10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72682
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87311
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60479
P4HB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09887
galactosylceramide catabolic process	GO Biological Process Annotations 2025	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73582
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28222
GATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62177
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06946
correlation	GeneRIF Biological Term Annotations	1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13367
glucosylceramide metabolic process	GO Biological Process Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6539
GCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00848664
SALL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570511
BRD-K67950754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23549
AGTR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530905
PRKD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654387
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911595
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.23773
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48981
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22006
PYCR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1783
IDUA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600756
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
FBXO22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533133
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
genital neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.262635
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.02
HRH3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594177
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	0.95492
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32933
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.18469
BRD-K70057550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.17588
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54404
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4484	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39313
PIR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.006125
glycosylceramide catabolic process	GO Biological Process Annotations 2015	1.0	null
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0363
NCOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37819
BRD-A20305532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17345
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24402
BRD-K19691332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30964
Urinary metabolite levels in chronic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.6699
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13708
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
2-Hydroxy-2-methylpropanenitrile	MW Enzyme Metabolite Associations	1.0	null
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26915
sphingolipid catabolic process	GO Biological Process Annotations 2025	1.0	null
modelling	GeneRIF Biological Term Annotations	1.0	null
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
male reproductive organ cancer	GWASdb SNP-Disease Associations	1.0	0.48135
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63828
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84174
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09893
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01396