association	dataset	threshold value	standardized value
AP-1 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.506
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21875
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
YUHOIN0650	DepMap CRISPR Gene Dependency	1.0	2.3611
Multiple synapse bouton, contacting multiple dendrites	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45586
abnormal olfactory epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
PIAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46308
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal craniofacial morphology	MPO Gene-Phenotype Associations	1.0	null
GSE125219,GSE125221_5_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.334
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63885
ARHGEF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86647
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16663
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.63412
Septin collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.977
SUSA	DepMap CRISPR Gene Dependency	1.0	2.01061
SLC49A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20887
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
ASPC1	DepMap CRISPR Gene Dependency	1.0	3.14683
CHP134	DepMap CRISPR Gene Dependency	1.0	2.11573
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63312
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56932
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849456
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94745
abnormal respiratory system morphology	MPO Gene-Phenotype Associations	1.0	null
trans-Golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.486
Perturb_3934_KO_TFAP2A_SRP273704	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.9996
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53942
CCDC9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95649
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95939
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884002
abnormal nose morphology	MPO Gene-Phenotype Associations	1.0	null
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11157
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100511_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83796
496100614_PCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55295
Perturb_6748_KO_TDRD3_SRP345494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.33183
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72011
HIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31477
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.91155
RUNX1	ChEA Transcription Factor Targets	1.0	null
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32608
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92057
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
TMEM104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94861
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18866
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0231
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41114
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.798
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52694
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11419
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6106
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21077
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73051
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06852
Perturb_4370_KO_TP53_SRP346812	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.12052
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN	CCLE Cell Line Gene CNV Profiles	1.0	1.73498
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46492
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52553
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92536
CAL120	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37635
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2602
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07357
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9221
Perturb_17291_OE_lncRNA5251_SRP239064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.34294
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8681
ACOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40562
CCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87226
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0811
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00634
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31407
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68745
Labellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67707
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62171
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.27873
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19432
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8756
Nasal cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
response to stimulus	GO Biological Process Annotations 2015	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Fhm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0039
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.43746
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56125
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31882
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11362
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16228
ZC4H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26749
COMA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
SP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09744
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84205
Sinonasal undifferentiated carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3688
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75433
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66661
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00978
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	2.42754
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30681
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07884
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04537
intrinsic component of organelle membrane	GO Cellular Component Annotations 2015	1.0	null
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49602
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.66628
Palisade parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6043
ATL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35267
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6089
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82543
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92546
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.333
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22733
FBXO42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52156
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68824
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4028
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3408
ZNF568	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46464
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23671
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Extraocular retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	2.20693
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
T-REx 293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44322
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
DVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11516
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56416
cellular localization	GO Biological Process Annotations 2015	1.0	null
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39735
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46754
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18532
Vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65879
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32432
SNU886	DepMap CRISPR Gene Dependency	1.0	3.26251
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20353
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00574
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1782
METTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05438
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04642
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40168
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6954
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55921
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0618
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69445
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1789
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22633
clathrin-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.293
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01301
protein localization to nonmotile primary cilium	GO Biological Process Annotations 2015	1.0	null
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21128
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
VPS4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
MYRFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0212
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30065
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.588
LINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2986
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU886	CCLE Cell Line Gene CNV Profiles	1.0	1.4162
LS123	CCLE Cell Line Gene CNV Profiles	1.0	1.6794
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.83343
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2578
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1121
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95285
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18713
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7117
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967414
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24513
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96675
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14087
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85828
SNU1033	DepMap CRISPR Gene Dependency	1.0	2.60973
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49341
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34041
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
RTN4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55911
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32432
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968557
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.59046
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09487
Perturb_10438_Mut_Adad2_SRP262140	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.9578
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24343
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68897
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87861
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65995
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16922
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05672
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48207
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2169
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40933
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.233
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08403
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53731
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29307
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01798
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BTN3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7059
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3797
Periderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35037
SYNGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57479
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09516
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23077
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16117
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50323
Perturb_16306_KD_FOXM1_SRP238685	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
r5 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3688
Perturb_10200_KD_HNRNPUL1_ERP118119	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.797
Acid phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07722
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2354
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52352
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57285
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11171
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42204
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3263
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60583
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03795
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57683
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ESRRG_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11412
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11412
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15428
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77759
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35802
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67423
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.9935
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59623
PRRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.246
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	1.0	1.62564
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.32415
C9orf72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20109
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54781
ACP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85563
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71114
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15036
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
impaired olfaction	MGI Mouse Phenotype Associations 2023	1.0	null
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67664
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22571
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80889
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9746
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
KCNK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58897
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07216
RSBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85568
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80393
ZNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81421
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59693
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35035
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48259
impaired olfaction	MPO Gene-Phenotype Associations	1.0	null
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03339
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0118
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48574
GSE206516,GSE206518_5_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIRT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30091
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47821
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54642
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57542
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.2252
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
TMEM97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.002
496100290_PCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32498
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17698
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17309
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.6672
HEL	DepMap CRISPR Gene Dependency	1.0	2.09447
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29339
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92369
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.877
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
UCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17284
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90643
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96489
JVM3	DepMap CRISPR Gene Dependency	1.0	4.24278
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4997
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17161
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.63251
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
IMPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43833
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
ATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51082
abnormal head morphology	MPO Gene-Phenotype Associations	1.0	null
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26084
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11064
NBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36612
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72974
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04284
Dendritic knob	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6701
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44314
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48995
taste/olfaction phenotype	MPO Gene-Phenotype Associations	1.0	null
WDR82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56877
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95295
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2245
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955039
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72494
Parasubthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17933
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33905
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12321
EXTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97531
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17933
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10547
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37165
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916837
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28151
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167984,GSE167987_0_v_1_setd1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57094
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86187
golgi apparatus part	GO Cellular Component Annotations 2015	1.0	null
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15873
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8196
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2122
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14727
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01581
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
MG63	DepMap CRISPR Gene Dependency	1.0	2.5272
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15647
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03314
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34829
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	2.47843
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08756
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12709
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
TP53BP1_KD_GSE54268_669_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15658_KO_Mettl3_SRP352450	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.42466
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3675
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39416
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4484
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4342
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48474
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33418
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47449
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13229
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.9841
PMC9306206-12915_2022_1367_MOESM6_ESM.xlsx-Table_S7_-_JIP-Gene_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.7106
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07348
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87991
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.479
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99692
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93459
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98936
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40992
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3747
abnormal olfactory epithelium cilium morphology	MPO Gene-Phenotype Associations	1.0	null
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6649
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90731
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14349
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89985
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
D502MG	DepMap CRISPR Gene Dependency	1.0	5.61735
ELAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61482
L-cysteine desulfurase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
LRIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84844
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22571
GSE166783_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
messa/dx5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23793
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968557
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16903
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.381
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78362
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36001
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3132
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75351
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9012
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33216
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
496100399_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34745
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
CH-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57285
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15731
ONS76	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58249
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67828
NCIH1339	CCLE Cell Line Gene CNV Profiles	1.0	1.43908
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55643
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5402
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26384
RI1	CCLE Cell Line Gene CNV Profiles	1.0	1.8312
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SFT2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83546
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13973
NCIH2087	CCLE Cell Line Gene CNV Profiles	-1.0	-3.12767
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849641
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9242
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92043
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4988
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03587
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97623
Perturb_643_KD_FASTKD1_SRP299834	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.98461
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47976
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
OVSAHO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7989
Nymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22889
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16761
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05756
Upstream stimulatory factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.215
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35561
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8986
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882863
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23906
Split septin rings	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.342
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884002
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
RIPK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35865
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19161
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99858
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89102
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
SLITRK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9333
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3107
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
cellular_component	GO Cellular Component Annotations 2015	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.318
OSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87173
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60076
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06668
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67499
OV90	CCLE Cell Line Gene CNV Profiles	1.0	1.34002
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4691
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35804
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.07589
Clathrin vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30243
Synovial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0653
GSE122101,GSE122103_0_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99888
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53084
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2315
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24847
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02271
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22994
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40824
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09307
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22633
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60413
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PDE5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916837
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05892
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850684
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.3333
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36939
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1287
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.1294
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99555
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.322
membrane part	GO Cellular Component Annotations 2015	1.0	null
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46311
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8682
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29522
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21024
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6554
cellular component organization	GO Biological Process Annotations 2015	1.0	null
AP-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.269
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3755
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100627_TCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59119
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7394
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97515
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21027
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15327
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17698
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22628
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
Septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.619
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4677
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43006
bounding membrane of organelle	GO Cellular Component Annotations 2023	1.0	null
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42097
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92548
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-CESC_AND_UCEC_NOT_BRCA_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58041
trans-Golgi network transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.504
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4116
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76179
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22438
SOCS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8597
BYSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52381
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51018
cellular macromolecule localization	GO Biological Process Annotations 2015	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.08175
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2902
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31852
FGFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2443
RASAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4037
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12742
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
AGS	CCLE Cell Line Gene CNV Profiles	1.0	1.60732
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08778
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06297
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.57076
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26882
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47503
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34277
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9703
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RL	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17546
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8986
NAA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46851
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Clathrin adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.275
CFAP126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90657
APEH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89202
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71954
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18533
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17101
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.174
protein localization to organelle	GO Biological Process Annotations 2015	1.0	null
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
WEHI-3B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46656
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57571
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32432
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54986
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63493
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Supplementary_Table_2B_Contrast_ATF4-def_DMSO_2h_vs_HCT116_DMSO_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0048
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intrinsic component of golgi membrane	GO Cellular Component Annotations 2015	1.0	null
abnormal olfactory epithelium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1007
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
HEPG2	DepMap CRISPR Gene Dependency	1.0	2.05327
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40933
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32004
Perturb_13381_KO_CTIP2_SRP150394	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.98902
hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14087
system process	GO Biological Process Annotations 2015	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.193
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0741
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27302
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28526
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8462
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65935
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87148
NOL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50559
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9319
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16831
Perturb_14214_KO_App_SRP254653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.82519
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0768
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.453
a2780cis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04936
SKNDZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83299
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.6937
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12849
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.788
DPP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.583
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13978
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62509
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2125
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01352
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03883
LSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15465
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06758
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_9728_KD_CDYL_SRP234405	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.3715
PFSK1	DepMap CRISPR Gene Dependency	1.0	4.76096
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955039
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4301
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5405
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23814
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0344
NCIH1781	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63725
protein localization to cilium	GO Biological Process Annotations 2015	1.0	null
TET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31397
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916837
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20111
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39955
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8794
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34189
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31679
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34408
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38542
NCIH2452	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75322
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29752
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18956
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63757
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14272
cell part	GO Cellular Component Annotations 2015	1.0	null
A431	DepMap CRISPR Gene Dependency	1.0	2.30824
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38879
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0261
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49696
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32725
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58869
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
abnormal cell morphology	MPO Gene-Phenotype Associations	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57678
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26261
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11386
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41743
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39112
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50436
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77914
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94135
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2585
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41296
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75026
LGALS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13932
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72195
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.63433
localization	GO Biological Process Annotations 2015	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15524
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21423
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83099
Perturb_2917_KD_FOXO3_SRP325840	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.534
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.8735
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9581
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.32621
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30865
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7203
cellular process	GO Biological Process Annotations 2015	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
UMUC14	DepMap CRISPR Gene Dependency	1.0	2.00984
NCIH2170	CCLE Cell Line Gene CNV Profiles	1.0	1.74699
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07425
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0304
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35131
PMC11019363-mmc2.pdf-8-EBF1_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Supplementary_Table_2A_Contrast_ATF4-def_control_vs_HCT116_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98229
ABCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53626
MM383	DepMap CRISPR Gene Dependency	1.0	4.38268
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30381
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31818
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11535
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21362
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02117
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64942
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Annulate lamellae	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35848
GSE166783_4_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01646
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0185
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61606
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83903
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6595
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54069
craniofacial phenotype	MPO Gene-Phenotype Associations	1.0	null
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93483
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stinger	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09511
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.9523
integral component of golgi membrane	GO Cellular Component Annotations 2015	1.0	null
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03964
Paranasal sinus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3339
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53773
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96313
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76829
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884002
Mixed gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06852
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
abnormal olfaction	MPO Gene-Phenotype Associations	1.0	null
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.596
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.3846
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6066
PTPMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35432
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00686
TUNAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52221
AAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84187
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Plastid ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24113
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884002
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.545
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47747
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01405
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941772
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01518
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21779
FZD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53015
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02455
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.481
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15387
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.216
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.17185
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06714
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96234
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16945
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08868
SUM229PE	DepMap CRISPR Gene Dependency	1.0	5.48099
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.265
LB771HNC	DepMap CRISPR Gene Dependency	1.0	3.64524
NUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7888
FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34469
C18orf32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51478
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09001
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02092
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01025
Perturb_17298_KO_Ptbp2_SRP071653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.81016
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60701
MOLM14	DepMap CRISPR Gene Dependency	1.0	6.06286
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882863
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01127
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2911
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07451
anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
Gin4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05976
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76038
DDX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07159
Microbody lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
Coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.168
Glyoxysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47909
CCAAT-binding factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.609
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4663
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90221
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14173
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33035
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33113
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein localization	GO Biological Process Annotations 2015	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829553
TNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32267
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37238
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8013
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45412
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30362
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67777
FOXE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39085
GPATCH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32921
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22731
SLC39A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71676
biological_process	GO Biological Process Annotations 2015	1.0	null
SELENOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71166
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24356
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13757
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28211
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04181
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsomedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31604
Chloroplast large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.665
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98487
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31998
LU165	DepMap CRISPR Gene Dependency	1.0	5.218
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27124
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68804
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29592
SF172	CCLE Cell Line Gene CNV Profiles	1.0	1.5403
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6178
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.16389
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79059
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50243
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39815
TR146	DepMap CRISPR Gene Dependency	1.0	3.40487
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42741
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11762786-41467_2025_56379_MOESM2_ESM.pdf-3-IRF2_IRF2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850684
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12971
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19151
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27451
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76924
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61496
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848356
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07723
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5177
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06714
PIP5K1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26818
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72213
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03402
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3453
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77095
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21774
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71248
Carpal tunnel syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cellular bud neck septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.51564
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	95.4429
BC3C	DepMap CRISPR Gene Dependency	1.0	2.68099
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59202
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66403
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70342
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20457
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2317
CHL1DM	DepMap CRISPR Gene Dependency	1.0	2.21039
FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MCMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40879
OLFML2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30747
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02663
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67159
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02304
SCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93853
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968557
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55269
ACBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13581
DCAF12L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05593
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28041
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39863
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882863
Perturb_328_KD_GDF15_SRP201220	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.24408
TCF7	ChEA Transcription Factor Targets	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35216
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72839
abnormal olfactory epithelium cilium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE121824,GSE121826_0_v_7_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20933
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
TUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31405
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968557
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98288
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00174
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25752
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6801
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91657
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1463
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06048
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35132
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53363
WRL-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30762
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8126
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02981
GSE135514_2_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26328
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24891
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47239
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78533
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.908
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57285
TMEM214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8733
SLC12A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24027
SKMEL30	DepMap CRISPR Gene Dependency	1.0	4.16677
MYBL2	ChEA Transcription Factor Targets	1.0	null
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
abnormal nonmotile primary cilium morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51298
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42263
Perturb_17320_KO_miR106b~25_ERP121195	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43778
SDR39U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52272
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00193
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71533
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100454_FWM_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01025
Perturb_10646_KO_Bend2_SRP348014	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.09913
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66045
Neural crest cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32432
RCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60592
organelle part	GO Cellular Component Annotations 2015	1.0	null
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34985
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12431
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849641
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11535
integral component of organelle membrane	GO Cellular Component Annotations 2015	1.0	null
cell projection morphogenesis	GO Biological Process Annotations 2015	1.0	null
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26019
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6452
NPRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1109
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99321
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03847
MCC13	DepMap CRISPR Gene Dependency	1.0	4.15096
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29652
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37366
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32875
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rhinencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
DAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57298
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.7125
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55318
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59128
TSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62746
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5158
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05154
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21362
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85715
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2472
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85117
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45009
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58262
GSE105170,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21852
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.6526
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0536
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83054
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11812
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34922
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98522
SMIM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12235
COL9A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44012
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30312
RERFLCAI	DepMap CRISPR Gene Dependency	1.0	2.27666
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56582
ZHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04641
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.34646
SKNEP1	DepMap CRISPR Gene Dependency	1.0	2.30674
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36139
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.26054
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06007
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16193
ARH77	DepMap CRISPR Gene Dependency	1.0	4.51451
cellular protein localization	GO Biological Process Annotations 2015	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01518
Perturb_81_KD_CENPA1_SRP187530	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.64154
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39172
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cardiac microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
JHESOAD1	DepMap CRISPR Gene Dependency	1.0	4.40497
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24889
abnormal olfactory system physiology	MPO Gene-Phenotype Associations	1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83903
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50011
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53363
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39815
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Supplementary_Table_2C_Contrast_ATF4-def_DMSO_8h_vs_HCT116_DMSO_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
WT-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55317
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15835
SNU878	CCLE Cell Line Gene CNV Profiles	1.0	1.77901
Golgi membrane	GO Cellular Component Annotations 2025	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32525
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77163
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48353
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05472
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90131
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64978
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64328
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	3.10697
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45231
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42411
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5434
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38222
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2164
THRAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91523
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85153
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Supplementary_Table_2F_Contrast_ATF4-def_IGG_8h_vs_HCT116_IGG_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Clathrin coat of trans-Golgi network vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.505
Golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.166
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.64376
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64407
Perturb_17260_KO_Gja1_SRP247546	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.78746
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5129
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920827
HCC1195	CCLE Cell Line Gene CNV Profiles	-1.0	-2.42044
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43023
PMC9822887-41598_2022_27261_MOESM10_ESM.xlsx-HCT116_overlap_TCF7L2_CTNNB1_lo-Unnamed_1_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01518
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11401
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22668
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90579
Autosomal recessive Robinow syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4639
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17101
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11535
abnormal olfactory system morphology	MPO Gene-Phenotype Associations	1.0	null
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36819
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.27
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55566
cell part morphogenesis	GO Biological Process Annotations 2015	1.0	null
Brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
CLIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00493
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06313
Perturb_17955_KO_Snca_SRP377748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.23493
HMMR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26678
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19569
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.2672
LPS6	DepMap CRISPR Gene Dependency	1.0	3.58773
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93081
CDS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60914
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35666
Mitotic septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.912
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.21201
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.376
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40794
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Survivin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
DENND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91305
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01152
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18547
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47873
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11412
SKPNDW	DepMap CRISPR Gene Dependency	1.0	3.07102
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96234
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23514
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23552
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05571
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76775
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2488
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26038
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4663
SRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28968
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42287
DNA ligase IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07314
Cervical adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
abnormal olfactory epithelium physiology	MPO Gene-Phenotype Associations	1.0	null
MRFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72049
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72328
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20253
Robinow syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
Animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	1.45895
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32228
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850684
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5554
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2869
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44937
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4331
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64428
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8608
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916837
PDZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76407
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870819
Perturb_17263_KO_Gja1_SRP247546	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SMARCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01711
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44158
496100467_FWM_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47199
Perturb_6862_KO_CDK19_SRP299261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RAB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06708
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43595
P2URK562	DepMap CRISPR Gene Dependency	1.0	3.32826
intracellular part	GO Cellular Component Annotations 2015	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-2.461
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45105
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARFGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87184
POLR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28638
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20438
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99467
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42342
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54836
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.974
GSE154074_5_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41245
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63399
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08548
Plastid large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.618
Cleavage apparatus septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32698
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24028
Diamine N-acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52951
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79613
GSE169356_0_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45501
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7931
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03934
CADM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75142
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38034
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7851
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04022
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53266
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45606
Chloroplast ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41296
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26872
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4525
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99686
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22511
SEC24D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74631
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35431
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0531
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36704
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89516
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00686
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26882
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.2804
WASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78782
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968557
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0618
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47658
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23814
496100383_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70268
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5374
PTGER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62514
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34139
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08899
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37955
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.637
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
cellular component morphogenesis	GO Biological Process Annotations 2015	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74381
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33124
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21337
Fusome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9726
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75298
HT1376	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54418
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16476
AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21451
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11535
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
Perturb_13736_OE_MYCL_SRP277794	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.01663
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41296
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44758
Perturb_18608_KO_Bend2_SRP348014	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.76931
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100476_TCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.98397
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882863
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0529
ARID4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75743
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04011
PSS131R	DepMap CRISPR Gene Dependency	1.0	4.2222
Vitelline envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
Paw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
AP1M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1618
KNS81	DepMap CRISPR Gene Dependency	1.0	2.76453
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60522
cell projection organization	GO Biological Process Annotations 2015	1.0	null
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01726
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.092
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal facial morphology	MPO Gene-Phenotype Associations	1.0	null
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35978
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59942
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49419
ISX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3223
NCIH2126	CCLE Cell Line Gene CNV Profiles	1.0	1.7416
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15882
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04569
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44868
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3839
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02354
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00431
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99218
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7607
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49616
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35749
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15707
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24094
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54452
UPCISCC131	DepMap CRISPR Gene Dependency	1.0	2.4705
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4443
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
neurological system process	GO Biological Process Annotations 2015	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22511
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
Cellular bud neck septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
NUCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37619
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28362
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89586
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24356
KIFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91484
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9255
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14163
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8986
GSE146074_1_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	2.59204
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69891
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01454
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30082
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.1494
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8333
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55046
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26715
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
FIBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36174
HEATR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96706
SUM52PE	DepMap CRISPR Gene Dependency	1.0	4.83107
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99888
abnormal olfactory epithelium physiology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4925
J82	DepMap CRISPR Gene Dependency	1.0	2.41875
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10244
MDAMB435S	DepMap CRISPR Gene Dependency	1.0	2.27185
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.286
CMK115	DepMap CRISPR Gene Dependency	1.0	5.28213
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
Perturb_12127_KO_Dnmt3a_SRP033096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.78079
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31524
Mitochondrial inner membrane assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
MPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72316
RMUGS	CCLE Cell Line Gene CNV Profiles	1.0	1.82313
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
TLCD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93464
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.048
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11412
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57455
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41296
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13451
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55008
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.44347
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26441
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81763
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955039
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20974
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13918
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23207
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20116
Nasal cavity carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4312
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4031
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.078
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32432
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5671
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12482
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6683
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35888
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56971
abnormal respiratory epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
fatty-acyl-CoA synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7295
abnormal cilium morphology	MPO Gene-Phenotype Associations	1.0	null
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0151
cilium morphogenesis	GO Biological Process Annotations 2015	1.0	null
Golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
RGPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34455
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5364
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95211
CAMK2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87096
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37686
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14198
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11812
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02862
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42539
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37453
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.01
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
Amyloplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.386
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	2.0567
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92717
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9704
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0384
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63869
Golgi membrane	GO Cellular Component Annotations 2023	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NSUN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60662
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62708
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15825
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23212
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.17073
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59032
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73595
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20302
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2645
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06183
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
SCG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09765
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12051
Perturb_13701_KD_NKX21_SRP335544	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.50455
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
GAP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81913
developmental process	GO Biological Process Annotations 2015	1.0	null
Golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.896
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30168
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.47972
OSC19	DepMap CRISPR Gene Dependency	1.0	3.4712
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22346
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849641
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14459
FNDC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53684
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TM9SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84777
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3688
abnormal primary cilium morphology	MPO Gene-Phenotype Associations	1.0	null
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884002
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7317
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Prospore contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.698
Vacuolar transporter chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56303
ABCB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02265
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21128
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
sensory perception	GO Biological Process Annotations 2015	1.0	null
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75133
UBE2Z	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8093
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37451
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM106A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18725
RAB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65012
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67292
NCIH522	DepMap CRISPR Gene Dependency	1.0	6.04867
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9113
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16773
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63719
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10127
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4975
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.4139
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72282
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63183
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25683
Perturb_17316_KO_Tardbp_SRP321767	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.25762
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35216
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46391
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0289
Peroxisomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704