association	dataset	threshold value	standardized value
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
FIZZ2_KO_GDS4902_409_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65833
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12798
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.677238
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30082
BRD-K75990394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10166
right atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3356
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58344
basal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35744
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58272
tiratricol-2259	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51140037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6138
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73625
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.397811
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30704
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15316
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
Platelet Thrombus	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17858
Ec	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78109
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834198
BRD-A68913459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22552
Gastrointestinal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
metamizole sodium-4310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92891227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13916
GSE149075_3_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K38558166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10506
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976905
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.952
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.926967
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.929
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2691
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842278
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_13912_KD_TARDBP_SRP169127	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.89582
BRD-K75130046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55947
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01687
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47184
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14978
hydroxyzine-5006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
Endothelial cell_Artery_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
beta-TC6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4397
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48669
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61909412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51227
CAL851	CCLE Cell Line Gene Expression Profiles	1.0	1.51563
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585625
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2066	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87671
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35407043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15565
central	GeneRIF Biological Term Annotations	1.0	null
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
metabolic syndrome	GAD Gene-Disease Associations	1.0	null
Left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4158-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primarily	GeneRIF Biological Term Annotations	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hallermann-Streiff syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943131
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.213283
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863237
Blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.592
GTEX-SNOS-1426-SM-32PLY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878953
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.952116
BRD-K02334683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01538
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59774
GTEX-T8EM-1126-SM-3DB7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50358
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80918
BRD-K45185240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15739
GSE221004_3_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1657
BRD-K02565327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08747
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7591
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075579
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06497
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.5028
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04018
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82721
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
19168792-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41229
EFE184	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.85405
H4C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81879
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50079
22RV1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59741
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.41306
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	2.62236
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07772
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06984
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42185771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58628
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Triglyceride levels x thiazide or thiazide-like diuretics use interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902611
terbutaline-3202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30005
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.59445
BRD-K56253099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27492
Vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.05
changes	GeneRIF Biological Term Annotations	1.0	null
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93762
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87227
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28593
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889479
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18955
Yolk sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.479
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell-cell junction	GO Cellular Component Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45734531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73609
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81564
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
CAKI2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56689
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10712
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935405
BRD-K60057192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12185
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15582
Follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.624
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49941
BRD-K78944047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34728
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917383
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34465
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60036
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.852274
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.319726
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arterial endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.821085
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
PMC10756545-pone.0296454.s002.xlsx-8_Normal_premalignant_modules-N10_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34356
22RV1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00977
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877773
ETF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48777
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077846
BRD-K13110820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34523
Perturb_9149_KD_VIRMA_SRP307037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.41899
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.899
fulvestrant-5565	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59205024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24925
dimethadione-4607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07395
BRD-K49530286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01672
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.835318
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990581
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3454-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cx37	GeneRIF Biological Term Annotations	1.0	null
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93448
BRD-K78658063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49986
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.628457
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87316
HCC1187	DepMap CRISPR Gene Dependency	1.0	5.73066
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66554
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89218
trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079405
OVSAHO	CCLE Cell Line Gene Expression Profiles	1.0	1.42618
Psp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
Superior mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433374
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33058
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
L-methionine sulfoximine-2831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ovary	GeneRIF Biological Term Annotations	1.0	null
BRD-K39985369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16418
BRD-K01266518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33841
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.96215
RAD51B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82938
RBBP5	ENCODE Transcription Factor Targets	1.0	null
POR_DELETION_GDS1093_240_mouse_Liver from male 3 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04303
16455817-Figure1E	GeneSigDB Published Gene Signatures	1.0	null
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21366
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5512555__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Tubulobulbar complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
BRD-K19776718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76591
BRD-A01717918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03046
divalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958284
MYOD1	ENCODE Transcription Factor Targets	1.0	null
abnormal female genitalia morphology	MPO Gene-Phenotype Associations	1.0	null
substrate	GeneRIF Biological Term Annotations	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K27354087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97999
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13045
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49249
BRD-K82324807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19645
BRD-K88543505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13654
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.892129
RAB5IF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12162
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SF539	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78047
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28688
CH157MN	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19108
Junctional zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84902
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.21547
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01962
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54J-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3641
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052877
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98876
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81647247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35489
Atenolol	CTD Gene-Chemical Interactions	1.0	null
cytisine-6217	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68782
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843635
spiradoline-3901	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82138
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01109
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.00568
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38892
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59064
STK31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2712
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3934	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13328
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17836
Hyperplasia	CTD Gene-Disease Associations	1.0	2.19379
Hereditary lymphedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.997
BRD-A89575866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44255
TBX5	ChEA Transcription Factor Targets	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942945
Perturb_11712_KO_Kpna3_ERP009054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MOG-G-CCM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975609
Mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.489
TOMM40L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79577
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90992
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
F12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6782
Anchoring junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SKMEL5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26348
intercellular	GeneRIF Biological Term Annotations	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	1.77641
Brain endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.466
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63384
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.87329
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.329837
investigates	GeneRIF Biological Term Annotations	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
pipemidic acid-6470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34744
Other Ureteric Obstruction	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K30682979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16031
GSE233679_14_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
YWHAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1702
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58364
OV90	CCLE Cell Line Gene Expression Profiles	1.0	1.50551
BRD-K07384081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0851
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
liver	Phosphosite Textmining Biological Term Annotations	1.0	null
macrophages	GeneRIF Biological Term Annotations	1.0	null
Venous endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.134
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07234
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58438
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61864
RD	DepMap CRISPR Gene Dependency	1.0	2.2199
Myocardial Ischemia	DisGeNET Gene-Disease Associations	1.0	null
Integrin alpha9-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCIM2	DepMap CRISPR Gene Dependency	1.0	2.47488
BRD-K02093145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15836
kaempferol-7196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55D-0326-SM-48FES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31932
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.813562
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Rad51C-XRCC3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29522
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987472
SFT2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06281
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.985633
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S5-Supplemental_Table_S5_Differentially_expressed_genes_between_cases_with_CM-induced_pY-STAT3_DMFI_1_76_STAT3_Low_v_DMFI_1_76_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.369373
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.894565
CRCGN015_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5243
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.5418
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839316
Microvessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.613
GTEX-X3Y1-0926-SM-3P5YT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06905
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23937
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pseudocumene	CTD Gene-Chemical Interactions	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892653
necessity	GeneRIF Biological Term Annotations	1.0	null
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6206
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-4.91932
Connexin, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056948
SMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14312
HUP-T3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.75
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855955
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32604
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
Melanophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23445
phenacetin-2471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
metaanalysis	GeneRIF Biological Term Annotations	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02806
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90753
BRD-K02100640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32011
insignificant	GeneRIF Biological Term Annotations	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1158
investigated	GeneRIF Biological Term Annotations	1.0	null
vascular	GeneRIF Biological Term Annotations	1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.445
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.11015
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.44452
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02242
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01237500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90653
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16818636-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K39773004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.395
BRD-K51054234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96838
HDAC_INHIBITION - trichostatin A_GDS2452_709_human_Endothelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cavernous hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
BRD-K21671578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51017
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06594
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-519e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
female infertility	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K81372870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99843
PTGES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83307
USP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85239
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.827171
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99603
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86345
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25023
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SQ-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hydralazine-3724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.756287
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15586
GSE206270_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K00505499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21679
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212761
Salivary_Gland-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0517085
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52556
Liver Failure, Acute	CTD Gene-Disease Associations	1.0	1.01474
TYMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49548
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21378
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957452
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30964193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12644
Right ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
hyperstimulated	GeneRIF Biological Term Annotations	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A94465834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1681
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843043
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
hsa-miR-654-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
P3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38847
BRD-K82176569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41224
MZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846212
BRD-K56563145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69703
BRD-K83603369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01942
BRD-K94921631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04536
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5245
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.136048
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900166
Adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.919
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986187
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.155
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00273
thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103059
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_0_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.02565
BRD-K24532125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16658
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929164
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944646
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76695
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC5789885-41467_2017_2812_MOESM4_ESM.xls-Supplementary_Data_1-Supplementary_Data_1_Non-cardiac_mesoderm_and_endoderm-permissive_differentiation_of_EOMES_KO_hESCs_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.48652
RCHACV	CCLE Cell Line Gene Expression Profiles	1.0	1.57131
BRD-K54593730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13231
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.199
succinylsulfathiazole-2166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hypomyelinating leukodystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
COQ8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36105
BRD-K00209945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02425
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57896
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420766
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29925
fh30	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041704
BRD-K81656074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3493
exchange	GeneRIF Biological Term Annotations	1.0	null
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12946
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33131
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
L363	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.5966
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76105
BRD-K59002219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49545
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872794
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02973
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.961
deleted	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23632
Glomerular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
RUNX1	ChEA Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37793
Pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
spleen	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZDHHC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1614
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77865
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14993
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098169
AP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53608
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15538
Brain endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.085808
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.13
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94293
Collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2268
BRD-K74500173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38875
GSE228125_0_v_3_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal ovary morphology	MPO Gene-Phenotype Associations	1.0	null
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
OPRM1	Pathway Commons Protein-Protein Interactions	1.0	null
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72022
flow	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5120-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.751
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32702774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65689
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
propensity	GeneRIF Biological Term Annotations	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09461
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08537
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02978
pirenzepine-7226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98273
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72613
PMC4833939-13072_2016_65_MOESM9_ESM.xls-PU_1_KD_SAHA_SigGenes_txt-gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1193
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906366
Perturb_4305_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.0724
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D4_vs_D9-Unnamed_2_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69005
influence	GeneRIF Biological Term Annotations	1.0	null
BRD-K19387722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97107
BRD-K95574976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75266
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910657
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35088
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05873
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12255
Astrocyte projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
MMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40557
femoral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.335968
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01093
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21235
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stenting	GeneRIF Biological Term Annotations	1.0	null
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93333
Vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.16
Atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.778
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043447
Brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.214
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5136
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K80807286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08261
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ami	GeneRIF Biological Term Annotations	1.0	null
BRD-K32930844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03552
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.46193
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
JAK1_druginhibition_165_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44156
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1396
prdm1_00000000_e9dot5_placenta_lof_mouse_gpl6887_gse39584	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.886417
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53188
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37603
Ischemic Stroke	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35774
huvec cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.943075
BRD-K83139520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71266
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992444
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04255
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22525
Osteocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.646
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.069
Vascular endothelial cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Theca externa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.48598
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10192
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.47115
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.25651
Fibroblast_Prostate_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19002
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51178
cefotetan-4116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41548770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40667
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-11A-12R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35009
GSE229698_1_v_2_traf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1398
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
SEC23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39361
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057753
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60364
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54762
Extraglomerular mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.92753
Myocardial Infarction	HuGE Navigator Gene-Phenotype Associations	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919073
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08997
PMC5819186-13040_2018_163_MOESM3_ESM.xlsx-Lung-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
STAT6_01_50	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61501
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.509
Epithelial cell_Transformed artery_Human	CellMarker Gene-Cell Type Associations	1.0	null
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23298
Peripheral motor neuropathy_Sciatic Nerve_GSE1947	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.15179
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0038
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corpus cavernosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.25562
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71699
Ovarian Infertility Genes(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
BRD-K72773830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37391
HHV-8_72Hour_18587055_GSE6489	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.04832
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00995
BRD-K15343767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18975
Mesonephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.136
Endothelial cell_Artery_Human	CellMarker Gene-Cell Type Associations	1.0	null
coronary artery disease	GAD Gene-Disease Associations	1.0	null
BRD-K89584810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25998
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14997
contribute	GeneRIF Biological Term Annotations	1.0	null
pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.324094
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Vitelline envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
endotheliumdependent	GeneRIF Biological Term Annotations	1.0	null
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70336
Primary pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7156
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07785
KCNC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67102
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065273
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05841
17284527-TableS2	GeneSigDB Published Gene Signatures	1.0	null
ACT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
Brain Edema	CTD Gene-Disease Associations	1.0	1.01062
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1092	DepMap CRISPR Gene Dependency	1.0	2.17264
Brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
Prostate adenocarcinoma_PRAD_TCGA-EJ-5518-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4360_KO_CEP83_SRP379856	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.85568
BC3C	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84385
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7351
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35214
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2377
TBX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38237
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15895
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	154.671
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887868
BRD-K18402224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48327
BRD-K39390441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07415
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.182
Perturb_17820_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.6719
induction	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04612
Hereditary lymphedema II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07465
PMC12802643-mmc10.xlsx-EC2-EC2_Endothelial_subcluster_2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Lamellar body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.107
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Olfactory glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10373
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837962
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877773
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75009
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.733
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16475
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903311
Endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.608
Apical ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061429
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082875
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	0.920149
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23907
galactosemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.179802
BRD-K41135617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34343
protective	GeneRIF Biological Term Annotations	1.0	null
mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.995425
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89918
Ectoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
clozapine-1229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BMP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
BRD-K63145472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31958
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.16339
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44101
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-12.2916
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	1.1484
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34998
Perturb_11817_KO_Nudt14_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.74105
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8367
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971975
Perturb_14789_OE_GPRC5C_ERP125648	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.77062
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930525
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell junction	GO Cellular Component Annotations 2025	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.533
SCLY	ChEA Transcription Factor Targets	1.0	null
abnormal internal female genitalia morphology	MPO Gene-Phenotype Associations	1.0	null
propose	GeneRIF Biological Term Annotations	1.0	null
GTEX-S32W-2026-SM-4AD6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81581
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11614
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2166
Pancreatic cystadenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084816
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.80891
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SLC35A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1874
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.79885
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68005
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04303
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.29336
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23280067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45073
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38532
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02849
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
moderate	GeneRIF Biological Term Annotations	1.0	null
glycemia	GeneRIF Biological Term Annotations	1.0	null
CORL47	DepMap CRISPR Gene Dependency	1.0	4.93442
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2835
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.84725
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50260295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47057
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57182
half	GeneRIF Biological Term Annotations	1.0	null
BRD-K41405597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05024
Great saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.205254
meclozine-5244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08619
Ovarian infertility	WikiPathways Pathways 2024	1.0	null
Pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.505
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11942
BRD-K12328371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56898
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
measured	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
monensin-2580	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17192395-TableS1	GeneSigDB Published Gene Signatures	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614974
here	GeneRIF Biological Term Annotations	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30111
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14265
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86744
Placenta	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.848223
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30053
BRD-K44177046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34618
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15492
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.63747
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8412
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05696
BRD-K18763924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31668
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961976
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58057
BRD-K26306512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1968
shear	GeneRIF Biological Term Annotations	1.0	null
BRD-K85615919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91106
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57094
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-C-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60152
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Osteosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
BRD-K45398957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14899
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.016
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937913
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0161
DMD_Deficiency_GDS2996_614_mouse_Cardiac muscles from 10.5-month (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00122
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03885
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.6511
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0932
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17531
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997303
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
DUSP1_KO_GDS1606_775_mouse_Spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5456
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57744
hesperetin-5350	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Fetal Membranes, Premature Rupture	HuGE Navigator Gene-Phenotype Associations	1.0	null
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00579
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89813
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45935
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
without	GeneRIF Biological Term Annotations	1.0	null
vascular hemostatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.410161
BRD-K69269415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07657
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932593
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.904574
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.99641
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58825
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23216
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Renal outer medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
BRD-K55018894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06998
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29339
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84448
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.984277
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57565
Pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.94794
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89608
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52265
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
DICER1_KO_GDS4504_584_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
iocetamic acid-4425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950448
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09622
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06219
junctions	GeneRIF Biological Term Annotations	1.0	null
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883283
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3097
GSE223008_11_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0629
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34609
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.30177
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.311
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.55698
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838021
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1417	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.41352
cardiac purkinje fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358919
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3515
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1195
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.02505
ccd	GeneRIF Biological Term Annotations	1.0	null
levocabastine-3509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.05942
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.522
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08323
BRD-K04704273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29502
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04308
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43606
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01431
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
BRD-K05223209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41527
BRD-K33420995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10866
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Angioblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.372
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.169859
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32551
NANOG	ChEA Transcription Factor Targets	1.0	null
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08664
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
CARBENOXOLONE	DGIdb Drug Targets 2026	1.0	0.508961
Anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.882
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.83799
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32696
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24428
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO684	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86918
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15225
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.845676
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A9-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0699
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
GOLGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56514
LAMA84	CCLE Cell Line Gene Expression Profiles	1.0	1.47677
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Porcine aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
demonstrate	GeneRIF Biological Term Annotations	1.0	null
BRD-K37336973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33803
BRD-K66559139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35718
OXTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25502
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.315366
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-0226-SM-4AT4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922413
iliac artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.639214
BRD-K85656316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20167
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043501
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PKBalpha_KO_GDS1784_196_mouse_Embryonic fibroblasts (MEFs) - 24h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14268
lymph vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.441426
SLR26	DepMap CRISPR Gene Dependency	1.0	3.57888
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66936
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03283
BRD-K22875057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20725
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11004561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33678
Anemia	CTD Gene-Disease Associations	1.0	1.01025
andor	GeneRIF Biological Term Annotations	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877773
tinidazole-2568	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92419
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31354
ZNF581	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80177
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UACC-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74837
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vesicle-mediated transport	Reactome Pathways 2024	1.0	null
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.05386
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.046
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36075
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06774
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.6935
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7418
GSE162688_3_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
helical	GeneRIF Biological Term Annotations	1.0	null
Anovulation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
abnormal sex gland morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K38046923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39955
Hypomyelinating leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.348
BRD-K97170716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51136
Hyperammonemia	CTD Gene-Disease Associations	1.0	1.02896
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43965
follicles	GeneRIF Biological Term Annotations	1.0	null
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.825768
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054147
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46812
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21365
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
GALNT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84871
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38949
HEL	CCLE Cell Line Gene Expression Profiles	1.0	2.2725
BRD-A94366206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32261
proline-rich	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K44061011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07504
Inflammation	CTD Gene-Disease Associations	1.0	1.89976
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994145
etofylline-2256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
16488994-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925801
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901112
mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.189829
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell communication	GO Biological Process Annotations 2015	1.0	null
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059433
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15489
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058036
BRD-K54732353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0511
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068255
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907608
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21827
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922056
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055073
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.219057
wide pore channel activity	GO Molecular Function Annotations 2025	1.0	null
healthy	GeneRIF Biological Term Annotations	1.0	null
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09742
BRD-K20912596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04183
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46357
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930021
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42315
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62747
Liver Cirrhosis, Experimental	DisGeNET Gene-Disease Associations	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.41471
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94822
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.119917
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712549
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.532078
islet cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.733001
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIVF001-007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28725
Ectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
Inferior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
BRD-K36111748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53089
used	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfamerazine-3616	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alterations	GeneRIF Biological Term Annotations	1.0	null
GTEX-XXEK-2426-SM-4BRUS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69742
BRD-K27885385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48597
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.012
BRD-K79334072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34796
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chronic venous insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88938
BRD-K70148257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04199
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044699
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38803
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0556
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.458759
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53438
mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04986
BRD-K50092006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24177
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24381
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4886-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
BRD-K51515697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26749
BRD-K31559225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72009
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.988
Mammary myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53901
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
gap junction	GO Cellular Component Annotations 2025	1.0	null
sirolimus-2667	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Venous hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066047
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.167
Vascular hemostatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
PPME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61229
Chronic Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K52977489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4497
Diabetes Mellitus, Type 1	HuGE Navigator Gene-Phenotype Associations	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.495
CA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11388
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13651
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04601
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.61575
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.39563
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
RAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20326
phenindione-2868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11115
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
BRD-K52924481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06273
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1048
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
CRCGN010_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02602
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866965
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16831
MEOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91549
GRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17753
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29758
carvedilol	CTD Gene-Chemical Interactions	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07402
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
artery	GeneRIF Biological Term Annotations	1.0	null
MOLT-16	GDSC Cell Line Gene Expression Profiles	1.0	1.49488
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
cad	GeneRIF Biological Term Annotations	1.0	null
Perturb_11834_KO_Rilp_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.11505
gap junction	GO Cellular Component Annotations 2015	1.0	null
OCTANOL	DGIdb Drug Targets 2026	1.0	0.630143
prochlorperazine-5575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal female reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
teratocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173057
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.564833
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8543
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980408
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33891642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0409
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96011
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_5_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.73858
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90102
GABPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09374
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.779401
Syndactyly type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42594
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.362
BRD-K77965546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50308
BRD-K85636571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09419
Endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.839
TGOLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.59612
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
Formal thought disorder in schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
SNU1033	DepMap CRISPR Gene Dependency	1.0	2.68141
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29956
Abdominal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
Testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
hsa-miR-936	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
PANC1005	DepMap CRISPR Gene Dependency	1.0	7.65155
cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077606
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3EP-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A17635048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38158
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59476
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59008
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52864
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.369
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.68503
EW8	DepMap CRISPR Gene Dependency	1.0	3.68813
ticlopidine-4074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27825
benfotiamine-2177	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10691
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47405
Corona	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.205
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.46728
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.80333
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03985
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04282
respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174434
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07323
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4896
predisposition	GeneRIF Biological Term Annotations	1.0	null
BRD-K73831263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03915
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
notably	GeneRIF Biological Term Annotations	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.8372
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1368
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884591
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77320034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47482
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.084273
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23584
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88087
PMC12211054-spectrum.00100-25-s0002.pdf-6-FOXN4_FOXN4	Rummagene Transcription Factor Associations 2026	1.0	null
Hemangiosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887955
cheek pouch	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.57042
luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235748
CSTF2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05404
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
QGP1	CCLE Cell Line Gene CNV Profiles	1.0	1.38625
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17964
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30941
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36349
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68013
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03498
VCAP	DepMap CRISPR Gene Dependency	1.0	4.44944
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43729445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.831
Fat-myofibroblast cell	Tabula Sapiens Gene-Cell Associations	1.0	3.25766
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69478
BRD-K57382977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08482
hsa-miR-4742-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
18692832-Table1	GeneSigDB Published Gene Signatures	1.0	null
SH3GL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0975
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08819
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29895
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	0.900922
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
BRD-K08996393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2827
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
Hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
Hs-578-T	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93611
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099176
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
communication	GeneRIF Biological Term Annotations	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50863
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17802
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83057
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K43473008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05986
coronary disease; coronary heart disease; myocardial infarction	GAD Gene-Disease Associations	1.0	null
BRD-K92803674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67148
PMC9334849-Table_3.xlsx-subcutaneous_adipose_tissue-D1_VS_D9_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
KLE	CCLE Cell Line Gene CNV Profiles	1.0	1.41715
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.873089
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.266
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37536
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
ZMPSTE24_Deficiency_GDS3775_506_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K31460017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04026
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970944
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944041
Helicobacter Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10939
variants	GeneRIF Biological Term Annotations	1.0	null
against	GeneRIF Biological Term Annotations	1.0	null
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69916
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945828
Perturb_8483_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.9715
FLUFENAMIC ACID	DGIdb Drug Targets 2026	1.0	0.348237
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Acute Coronary Syndrome	DisGeNET Gene-Disease Associations	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12747
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
GSK3A_KD_GDS4305_180_human_MOLM-14 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K61206648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04744
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cardiac Purkinje fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
single organism signaling	GO Biological Process Annotations 2015	1.0	null
fulvestrant-6197	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45807
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49586
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072777
BRD-K74688087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36222
Sarcoma_SARC_TCGA-DX-A3M1-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3158-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K23405268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14093
BRD-K16746805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49431
Gap junction alpha-4 protein (Cx37)	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-X88G-0426-SM-47JZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01237
Brain capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
BRD-K35124958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35843
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2110	DepMap CRISPR Gene Dependency	1.0	2.067
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69889
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69113
18199535-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
aortic endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.672506
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
BRD-K72591075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85854
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
BRD-K30283890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03374
Edema	CTD Gene-Disease Associations	1.0	1.65045
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.04997
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922056
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24361
C32	Achilles Cell Line Gene Essentiality Profiles	1.0	1.13994
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32743
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54632
protein complex	GO Cellular Component Annotations 2015	1.0	null
Hypoglycemia	CTD Gene-Disease Associations	1.0	1.06261
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23871
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stress	GeneRIF Biological Term Annotations	1.0	null
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.22884
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75027
BRD-K40432489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5095
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65721
diabetes	GeneRIF Biological Term Annotations	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73269
BRD-K87146261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20761
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35995
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12254
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02726
hydrochlorothiazide-1487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13077
BRD-K12115687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53755
Cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.765
well	GeneRIF Biological Term Annotations	1.0	null
establishment	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05048
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91451
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8882
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49339
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59246
Ebolavirus(ZEBOV)_6day_PBMCs_rhAPCtreated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.031733
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15555
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05972
Catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.456
corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260606
provides	GeneRIF Biological Term Annotations	1.0	null
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358453
hsa-miR-760	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057163
BRD-K39078753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03395
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.555
Mammary myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
Amenorrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
Gap junction trafficking and regulation	Reactome Pathways 2024	1.0	null
abnormal corpus luteum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.801
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09505
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56761
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
atropine methonitrate-3116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARHGEF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30083
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0181
Prestwick-692-4424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Carcinoma	CTD Gene-Disease Associations	1.0	1.15967
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56139
GTEX-S4Q7-1126-SM-4AD6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956655
PRKACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33848
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07483
extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166405
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0926-SM-4AT4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06783
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
MYOG	ENCODE Transcription Factor Targets	1.0	null
macrophage foam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.421148
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08218
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.974001
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.20792
ARF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56127
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6077
Osteoclastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.06808
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15792
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049134
PDXP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507548
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.593
BRD-K28305165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18722
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59823
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21231
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50723
CORL24	CCLE Cell Line Gene CNV Profiles	1.0	2.59946
KP-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2768459-6605275x5.xls-Hoja1-Supplementary_Table_S2_Differentially_expressed_genes_within_the_ESR1-negative_BRCA1_tumors_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27002
vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.753297
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16994
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
gastric	GeneRIF Biological Term Annotations	1.0	null
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24851
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71636
17284527-Table2	GeneSigDB Published Gene Signatures	1.0	null
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.483
BRD-K13472433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37454
BRD-K77177732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01924
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cardiomyocyte_Heart_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876229
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A464-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23608
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17525
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K95591629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22499
Ovary	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
baec cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.444115
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3436
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35217
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10533
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19235
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10495
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07026
olfactory ensheathing cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254902
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533856
BRD-K51104732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81239
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87394
Neointima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
modify	GeneRIF Biological Term Annotations	1.0	null
ursodeoxycholic acid_mus musculus_gpl6246_gse22608	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POU3F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02798
cefalotin-6079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054273
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02354
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67082570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56603
TALL-1	GDSC Cell Line Gene Expression Profiles	1.0	1.95028
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.136809
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25554
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.51374
ofloxacin-4696	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
genotype	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898267
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43547
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Basement membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.893
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31571
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.67864
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
connexon complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
PMC4489805-pone.0132249.s008.xls-STAT1_T_cell_activation-Unnamed_4_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
nefopam-3627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5595
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903645
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.42428
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5361-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery cell_Blood vessel_Human	CellMarker Gene-Cell Type Associations	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09394
Blood vessel wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.976
BRD-K79576342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33865
Venous insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887033
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44105
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855955
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
tissue development	GO Biological Process Annotations 2015	1.0	null
placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K83341545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82938
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40971
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Myosin X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
Essential hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43948
Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95929
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.334384
Gap junction assembly	Reactome Pathways 2024	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WY7C-2726-SM-3NB3P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990192
jm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
acute myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.190786
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.986761
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133739
Cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.983
BRD-K45612428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12381
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.92291
GTEX-SJXC-0226-SM-2XCDU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03857
A375SKINCJ3	DepMap CRISPR Gene Dependency	1.0	2.81428
response to stress	GO Biological Process Annotations 2015	1.0	null
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90481
Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Obesity	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K60238606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04173
BRD-K76437403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00875
pentamidine-4396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Palmoplantar keratoderma-deafness syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
PR, GR	MotifMap Predicted Transcription Factor Targets	1.0	null
HEL9217	CCLE Cell Line Gene Expression Profiles	1.0	1.97139
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08399
BRD-K99331577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45401
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925815
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061822
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42502
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.56639
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
BRD-K52225720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08496
cx40	GeneRIF Biological Term Annotations	1.0	null
Mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.6
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78461
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53241
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60249
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66952
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6374
TEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18246
COQ10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01904
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A8S6-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell contact zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.048
ciclosporin-4411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
octanol	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05727
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27025
Thymus-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	4.96694
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
terguride-5400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.669657
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
Calcium Regulation in the Cardiac Cell(Mus musculus)	WikiPathways Pathways 2014	1.0	null
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30809
immature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.842867
PAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11097
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
LOVO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0186
FMNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33753
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OIZH-0226-SM-2YUMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45217
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.225
ovulation	GeneRIF Biological Term Annotations	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80658
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847913
Human - Tonsil - L2 - CD14+CD55+ FDC	HuBMAP Azimuth Cell Type Annotations	1.0	null
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
Uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
C6 glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
BRD-K39600742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20072
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
Cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.61736
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53505
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09561
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52571
GSE128333_4_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45774
Lung adenocarcinoma_LUAD_TCGA-55-6968-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65078
palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.264785
Bart-Pumphrey syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.935
midecamycin-6745	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal gland morphology	MPO Gene-Phenotype Associations	1.0	null
DCAF12L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05593
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37901
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941146
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9923
Cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
ascorbic acid-5407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01264
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.04683
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3834
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86595
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
SHI1	DepMap CRISPR Gene Dependency	1.0	3.25546
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42567
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.860018
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.10596
types	GeneRIF Biological Term Annotations	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23321
Acute Myeloid Leukemia_LAML_TCGA-AB-2859-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13411423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03268
Lung adenocarcinoma_LUAD_TCGA-50-5045-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Umbilical vein endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.979
BRD-K09663164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60267
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901256
myosmine-2199	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.175744
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62597218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.633
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
IQCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87015
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.00676
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20709
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878616
ZNF703	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34724
CAL-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P78B-0226-SM-3NB1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978766
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
angular gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98469
Ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.481
BRD-K55510118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20935
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59136
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
alpha	GeneRIF Biological Term Annotations	1.0	null
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12826618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19508
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35193
gap junction channel activity	GO Molecular Function Annotations 2023	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
endocrine/exocrine gland phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K92978173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51667
CRCGN013_HEPG2_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38304
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91624
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1426-SM-2S1P5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59431
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17069
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
AKT1_knockout_213_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.44296
Arteriovenous malformations of the brain	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
BRD-A96537953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06039
GTEX-S7SF-0826-SM-4AD4W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01312
junctions	Phosphosite Textmining Biological Term Annotations	1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.533
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.877988
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58088
glomeruli	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-541	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K96382853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87235
BRD-K44975377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07863
lymphedema	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.507657
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15192
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856596
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08416
Hemangiosarcoma	CTD Gene-Disease Associations	1.0	2.88009
BRD-K31218318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08105
Egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10875
skin	HPA Tissue Gene Expression Profiles	-1.0	-0.826759
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
BRD-K11566982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08951
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75243
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211128_2_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.67354
Liver epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
0317956-0000-3774	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
haplotype	GeneRIF Biological Term Annotations	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28601178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54292
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1388
LRIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99235
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
HMGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61844
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20956
BRD-K34095226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.7842
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89299
plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.696172
Atherosclerosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.395
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64546
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27036
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Iliac artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18955
Essential Hypertension	DisGeNET Gene-Disease Associations	1.0	null
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	6.69853
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96418
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.56894
GSE239898,GSE239899_1_v_0_hiltonol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K87167435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10288
atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449886
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16572
Gap junction trafficking	Reactome Pathways 2024	1.0	null
PMC12611713-Table2.xlsx-Sheet_1-Diabetes_AND_Validation_Database_NOT_Training_Database_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.998994
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062569
differentially	GeneRIF Biological Term Annotations	1.0	null
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43771
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
chlortalidone-6800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.207
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00275
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174209
SARS-BatSRBD_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.7917
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59175
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.622
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.32004
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56429
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916983
BRD-K06392309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55163
proliferation	GeneRIF Biological Term Annotations	1.0	null
monocytes	GeneRIF Biological Term Annotations	1.0	null
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.361
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886025
different	GeneRIF Biological Term Annotations	1.0	null
Perturb_7036_KO_Setd2_SRP301848	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.06883
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86719
Tek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.333
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990746
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39107553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24958
BRD-A99344113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63527
LRRC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48791
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.85365
betweenstudy	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066988
BRD-K14520048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59062
report	GeneRIF Biological Term Annotations	1.0	null
BRD-K17574409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03971
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27113
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.928166
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
Granulosa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.542
BRD-K56912308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58456
Acute Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	3.56486
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85491
adults	GeneRIF Biological Term Annotations	1.0	null
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.413
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26218
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.281085
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827468
BRD-K78074905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09401
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Prostate gland_CT1_perictye	HuBMAP ASCT+B Annotations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897276
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3BZ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15831
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Obesity, Abdominal	HuGE Navigator Gene-Phenotype Associations	1.0	null
placenta	HPA Tissue Gene Expression Profiles	1.0	1.14854
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29573
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.612958
Macrophage foam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78296
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
Pericyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.881
Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00981
Poisoning	CTD Gene-Disease Associations	1.0	1.23042
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.329
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0742
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19075
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38934
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5ST-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25591
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990581
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896239
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15545
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965944
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069053
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860747
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3886
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
Hematopoietic cell_Heart_Human	CellMarker Gene-Cell Type Associations	1.0	null
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79558
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40047
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.079
RAD21	ENCODE Transcription Factor Targets	1.0	null
abnormal female reproductive gland morphology	MPO Gene-Phenotype Associations	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041485
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061917
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58591
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062765
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64904
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
BRD-K76899562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17674
players	GeneRIF Biological Term Annotations	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913684
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nefopam-3730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0449
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88018
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.16666
Memory Disorders	CTD Gene-Disease Associations	1.0	1.70014
Cardiovascular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
northern	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4EP-0826-SM-3P5YK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59829
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59761
hypertension; lung cancer; abdominal aortic aneurysm	GAD Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90102
BRD-K11054415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23757
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	2.55745
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64798
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24793
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78767
ChIP_TIP60_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17165
BRD-K47165178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50441
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30197
BRD-K17372597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10261
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46873
JADE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27103
Prostate adenocarcinoma_PRAD_TCGA-HI-7170-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20953
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.41764
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2447
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57934
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1474
placenta_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.16877
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pulmonary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98014
vasodilation	GeneRIF Biological Term Annotations	1.0	null
ZC4H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23493
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042865
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05569
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28509
BRD-K04409515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50488
BRD-K56857396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05531
5155877-6549	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68042
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.593649
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07146
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.98577
BRD-K41133627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.718
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.107
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53258
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6227-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38063
BRD-K37386363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73678
chloride	Phosphosite Textmining Biological Term Annotations	1.0	null
Integrin alphaIIb-beta3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
COV318	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
intact	GeneRIF Biological Term Annotations	1.0	null
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99736
9,10-Dimethyl-1,2-benzanthracene	CTD Gene-Chemical Interactions	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980678
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43868
ciclosporin-1331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.13577
time	GeneRIF Biological Term Annotations	1.0	null
placenta_6c	HPA Tissue Sample Gene Expression Profiles	1.0	2.40462
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.846098
HYOU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76707
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.88213
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857477
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.25463
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cortical granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.624
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885688
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.712795
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY-294002-5596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CADASIL	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5345
Gap junction trafficking	Reactome Pathways 2014	1.0	null
Perturb_5584_KO_RELA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.024
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85547
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8956
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2468
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54757
simultaneously	GeneRIF Biological Term Annotations	1.0	null
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51415
BRD-K69468381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21956
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57246
piromidic acid-4398	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1557
BRD-K20271299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72673
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44663
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043243
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Charcot-Marie-Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
Acute myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
SRY	ChEA Transcription Factor Targets	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9891
BRD-K41774018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50697
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
KURAMOCHI	GDSC Cell Line Gene Expression Profiles	1.0	2.10954
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fenoprofen-4736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90997
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KRAS.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25083
subclinical	GeneRIF Biological Term Annotations	1.0	null
BTK_KO_GDS1346_302_mouse_splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_10779_KO_Slc25a34_SRP342539	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.33403
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06578
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.695763
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14112
BRD-K52154207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0661
EWSR1	ChEA Transcription Factor Targets	1.0	null
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
Coronary Heart Disease	DisGeNET Gene-Disease Associations	1.0	null
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97019
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48723
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26775
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088454
BRD-K50600207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05831
hsa-miR-4522	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.654
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46842
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.20625
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957277
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83958
Hypoplastic left heart syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
deptropine-5543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K93900188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48908
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29345
17192395-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
Vascular endothelial glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.929
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
moroxydine-6705	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Uterine leiomyoma_Uterus - Myometrium (MMHCC)_GSE593	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.07685
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GTEX-XGQ4-2426-SM-4AT55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956607
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.3645
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-1226-SM-3TW8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4806
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92512
STOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08361
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066988
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00016
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
methods	GeneRIF Biological Term Annotations	1.0	null
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47177
not applicable_asthma_GSE43696_369_mouse_bronchial epithelial cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Sarcoma_SARC_TCGA-DX-A6BG-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
higher	GeneRIF Biological Term Annotations	1.0	null
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35208
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31795
cation transport	GO Biological Process Annotations 2015	1.0	null
umbilical artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.707221
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061063
BRD-K01314849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12034
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1926
VPS45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99373
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23841
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28182
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913616
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055093
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06942
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061586
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06618
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842114
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.8634
BRD-K91085913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26006
Synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14965
Kidney Chromophobe_KICH_TCGA-KN-8424-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45845217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88605
BRD-K43237307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00369
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876645
Sarcoma_SARC_TCGA-DX-A8BV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cyclin B1-CDK1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.31
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846058
hsa-miR-3929	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
BRD-K46413323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21165
Vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.355
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
quinidine-5793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
induced	GeneRIF Biological Term Annotations	1.0	null
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73937
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PUM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73456
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3947
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837871
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01910220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43323
cumulus-oocyte complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.295
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.444115
Cerebral cavernous malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
connexin	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91180296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48172
presence	GeneRIF Biological Term Annotations	1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466498
Anterior cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.090588
PMC7706141__F8	PFOCR Pathway Figure Associations 2023	1.0	null
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41587
Geep	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
thalidomide-2258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.93157
PAX5	ENCODE Transcription Factor Targets	1.0	null
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51102
nash	GeneRIF Biological Term Annotations	1.0	null
BRD-K21470524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24936
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18955
Bladder-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	0.900489
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.90276
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99523
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF555	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56455
Mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838769
FIZZ2_KO_GDS4902_408_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
Perturb_9148_KD_KIAA0853_SRP307037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.93884
Capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.574
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62698
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K35808731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00906
hsa-miR-1224-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.066
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942325
MC-IXC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82919
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95019
pirenperone-4679	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEC22C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95628
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25374
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.40734
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
GSE136653,GSE136660_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1672
HSG	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.63918
Hennekam syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69I-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fluorometholone-6071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.68612
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042818
Corolla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2675
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	2.33707
BRD-K25312635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63384
Hypotension	CTD Gene-Disease Associations	1.0	1.01099
BRD-K45022385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0842
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05633
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.41954
AHCTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72601
BRD-K79072801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26555
BRD-K48147099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36596
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45417
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51867
GTEX-S95S-1326-SM-2XCDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01698
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183271_2_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymus-endothelial cell of lymphatic vessel	Tabula Sapiens Gene-Cell Associations	1.0	0.269345
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24743998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44083
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39207
hsa-miR-570	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE130217_0_v_2_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vasculature-artery endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.09636
RETREG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75341
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15657
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2694
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27375
COPD - Chronic obstructive pulmonary disease_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE475	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.46565
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866237
Hypb_Deficiency_GDS3641_523_mouse_Yolk sac from E10.5 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04591
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.844
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7455
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956436
etifenin-3998	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74951
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46762
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11542
SPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48728
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829465
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898025
signaling	GO Biological Process Annotations 2015	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.403
PSN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47382
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064203
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12048
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49849
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69751974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27011
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
connexon complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.471208
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.6638
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-2.83437
genetic	GeneRIF Biological Term Annotations	1.0	null
Lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_5_CXCL10-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6774-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital chylothorax	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
BRD-K50712773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97482
XPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38443
Artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.774
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.1554
Pacemaker cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81368
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969753
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060798
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07435
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17615
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64981
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4899-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99516890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28963
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.7314
responses	GeneRIF Biological Term Annotations	1.0	null
acute	GeneRIF Biological Term Annotations	1.0	null
KMCH1	DepMap CRISPR Gene Dependency	1.0	2.65184
helicobacter	GeneRIF Biological Term Annotations	1.0	null
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
retraction	GeneRIF Biological Term Annotations	1.0	null
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58959
ranitidine-5425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44916315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52707
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78506
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9128
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77646
BRD-K01615696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33222
BRD-K58066822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18644
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838082
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930797
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878519
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
WWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89614
cardiac muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289226
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
CRCGN015_MCF10A.TP53.M_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20103
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25487
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.97507
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
BRD-K11258719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0414
BRD-K64317863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07687
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30401
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06248
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
blood vessel development	GO Biological Process Annotations 2015	1.0	null
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44654
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
isocarboxazid-2562	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNF187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055262
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057034
Endothelial cell_Blood vessel_Human	CellMarker Gene-Cell Type Associations	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922056
angiosarcoma	PhosphoSitePlus Phosphosite-Disease Associations	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5073
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86453
95T1000	DepMap CRISPR Gene Dependency	1.0	3.58134
GTEX-U4B1-1726-SM-3DB9F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915406
e2f2_21245101_mmtv-myc_lof_mouse_gpl8321_gds4094	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.426596
BRD-K35308744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16793
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967844
Craniometaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.829
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_24_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
NB5	DepMap CRISPR Gene Dependency	1.0	2.99171
Cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.585
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.257
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73528
BRD-K62547690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05932
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892741
BRD-K02230174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63435
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pd5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39319
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28564
BRD-K65446780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06299
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31931
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3918	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
HPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86183
BRD-K12824862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45249
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A50E-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LK-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.92651
14990357-Table3	GeneSigDB Published Gene Signatures	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
dexamethasone_mus musculus_gpl81_gds250	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell-cell junction assembly	GO Biological Process Annotations 2025	1.0	null
erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04588
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3664-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16021
Lung adenocarcinoma_LUAD_TCGA-50-6595-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34335352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79995
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.28669
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59739
Lung-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	0.42169
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vascular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
BRD-K35826866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51526
CLNS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08206
wide pore channel activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884851
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.719113
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41237
embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K00590556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68425
ATP6V1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56232
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Connexin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
apparently	GeneRIF Biological Term Annotations	1.0	null
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K09975619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15375
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041191
BRD-K32947579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.13163
Tetralogy of Fallot	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.826
NCIH660	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13488
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41673
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30607
Microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51651
abnormal gametogenesis	MPO Gene-Phenotype Associations	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03949
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K47762331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82799
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89408
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866896
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.7716
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
PMC5725737-IJC-142-297-s013.xlsx-DTC_mna_vs_TUM_mna-DTC_MYCN-high_vs_TU_MYCN-high_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Umbilical vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
MSTO211H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4108
poor	GeneRIF Biological Term Annotations	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93045
Membrane Trafficking	Reactome Pathways 2024	1.0	null
Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10533
Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1258
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82488
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.25183
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71546
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.71675
manifestation	GeneRIF Biological Term Annotations	1.0	null
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.140643
BRD-A80723361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0546
GTEX-P4QS-0226-SM-3NB1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40263
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SUIT2	DepMap CRISPR Gene Dependency	1.0	2.29737
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.518
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.3793
Human - Tonsil - L2 - LZ FDC	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1398
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.74426
PMC7706141__F8	PFOCR Pathway Figure Associations 2024	1.0	null
Angiosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.957871
abnormal female meiosis	MPO Gene-Phenotype Associations	1.0	null
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51598
Tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.692
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849362
EGR1	ENCODE Transcription Factor Targets	1.0	null
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06374
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0173
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63799
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22367
el2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.841
DoTc2-4510	GDSC Cell Line Gene Expression Profiles	1.0	1.41967
case	GeneRIF Biological Term Annotations	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
extrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.889258
Carcinoma, Squamous Cell	CTD Gene-Disease Associations	1.0	1.14438
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1_01_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.42165
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2297
0173570-0000-3693	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96416
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_ATF3_SMC_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell-cell junction organization	GO Biological Process Annotations 2025	1.0	null
OCIMY5	DepMap CRISPR Gene Dependency	1.0	2.96677
nicotine_myzus persicae_gpl9470_gse18658	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prestwick-682-4984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.61162
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048186
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
coronary	GeneRIF Biological Term Annotations	1.0	null
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
Carotid artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29984
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20423
Ooplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.2369
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.159559
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309613
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34547
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35848
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35728
PPIF_KO_GSE23028_45_mouse_heart (8 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	3.54428
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054933
HS940T	CCLE Cell Line Gene Expression Profiles	1.0	1.41807
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31718
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069637
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23316
Saphenous vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.781
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879945
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.66007
BRD-K53088255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24697
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.978544
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
Ischemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24209
Membrane Trafficking	Reactome Pathways 2014	1.0	null
GSE211128_7_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32183
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90523
clopamide-5402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18955
layer	GeneRIF Biological Term Annotations	1.0	null
BRD-K34258763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09615
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02909
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302838
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5319-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
BRD-K63960902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65378
BRD-K01643633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20987
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41324679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27268
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05316
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NME6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90787
STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormal ovarian folliculogenesis	MPO Gene-Phenotype Associations	1.0	null
Uterus-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	2.51769
MLO-Y4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49282125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10855
Mammary-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0253012
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76378
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.092
Umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.486
Weibel-Palade body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.944
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06047
GSE223008_0_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40081
PMC11563688-jci-134-173448-s017.xlsx-EC2-gene_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.28827
LNCAP	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
impaired	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855303
COV504	CCLE Cell Line Gene Expression Profiles	1.0	1.38246
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09329
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
progesterone-4992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Junctional membrane complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.671
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	1.83466
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45049
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66039243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11331
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66316
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07254
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99516
DLX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34453
BRD-K45908502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37764
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48669
Chronic pulmonary heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20358
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
Perturb_3351_KO_Tsc2_SRP227934	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34645
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
allelic	GeneRIF Biological Term Annotations	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.264431
GTEX-WFON-2226-SM-3TW8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03797
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4576
BRD-K64451677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08275
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.35278
Prostate gland_CT1_perictye	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.852191
SNU-C1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4307
GTEX-XUZC-1126-SM-4BOPZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829638
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.33907
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Atrioventricular node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
JNK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57402
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60573
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4874
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966179
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00621
PHF8	ENCODE Transcription Factor Targets	1.0	null
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50001
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975807
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30126
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96079
CRCGN013_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2052
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NB-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17571080-SuppTable2a	GeneSigDB Published Gene Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.137641
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079208
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.953
Perturb_4867_KO_HES1/NEUROG3_ERP110708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.51148
CMK115	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
SCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93853
Pre-Eclampsia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Venule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.782
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.23775
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04394
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7433_KD_CNBP_SRP068194	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.72321
some	GeneRIF Biological Term Annotations	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.766
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44247
Cardiovascular organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
BRD-K26734305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21855
Blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.549
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41943
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04926
sulfapyridine-2538	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.878
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.881204
cell junction	GO Cellular Component Annotations 2015	1.0	null
FLT1_knockdown_111_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.89583
BRD-K37047627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2649
Fascia adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.089
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855618
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hemichannels	GeneRIF Biological Term Annotations	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18955
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16033
DICER1_KO_GDS4504_582_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24453
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84554
16397233-Table2	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92973
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.29551
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36155
BRD-K28885073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87636
hel12469	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29215
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29644
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866074
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51858914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48234
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05234
BRD-K52300725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54851
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64148
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045494
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
Embryonic cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82187446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09198
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.266
Atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.728
PMC7579924-12920_2020_778_MOESM1_ESM.xlsx-AA-Gene_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68254
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19791
BRD-K52049165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73693
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5176-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323874
Ovarian Failure, Premature	DisGeNET Gene-Disease Associations	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	69.3187
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53231
Capillary hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
junctional	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16193
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2562
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
Neuro-2a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.14479
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05942
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916662
Arterial cell_Embryo_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K53291208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41714
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Venous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.251
Liver Diseases	CTD Gene-Disease Associations	1.0	1.59896
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841781
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
delsoline-7212	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60607
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14863
GAS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26781
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46573
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.556
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11393
TYKNU	Achilles Cell Line Gene Essentiality Profiles	1.0	1.08867
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23456
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00421
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963906
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
seneciphylline-4238	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13942
Umbilical artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.251
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26183
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skimmianine-6242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-HEP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
TTC7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511051
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0476
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069719
Fatty Liver	CTD Gene-Disease Associations	1.0	1.91184
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847445
HDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02554
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06234
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12086
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72026
blood vessel wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14697
Lymphatic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.993
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00743
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25571
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45476
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4329-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47085
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
BRD-K93697231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07449
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T84	DepMap CRISPR Gene Dependency	1.0	2.54273
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QV44-1825-SM-447CF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69666
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29469525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84872
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell junction	GO Cellular Component Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal female meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
GSE188869,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Smooth muscle cell_Ovary_Human	CellMarker Gene-Cell Type Associations	1.0	null
Myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.754
Dermal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
BRD-K21713052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13055
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
microvessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225395
Umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.504
GSE211128_9_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35557
NCIH1781	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11311
umbilical artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.717882
HMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40693
BRD-K54785691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56895
ginkgolide A-4002	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48362
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45564
others	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46873
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55267
Charcot-Marie-Tooth disease X-linked dominant 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32584
Weight Gain	CTD Gene-Disease Associations	1.0	1.79637
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tranylcypromine-5996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.63306
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869705
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065665
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75872
HCT116	DepMap CRISPR Gene Dependency	1.0	3.64921
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31956
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.04832
BRD-K45734366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68122
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977598
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54086
Aorta endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.944
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53186055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10485
Luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64988
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatic artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
BRD-K79658624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16412
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97403
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82669
BRD-A04975445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22656
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38551
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.486
NCIH69	CCLE Cell Line Gene Expression Profiles	1.0	1.62055
length	GeneRIF Biological Term Annotations	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20349
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33256
Angina, Unstable	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-4476	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE221004_1_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CMK86	CCLE Cell Line Gene Expression Profiles	1.0	3.40827
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25759
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48615268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58803
Uterus-myometrial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.244233
fenoprofen-2553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.080817
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4993-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.069
eticlopride-5695	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890822
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965538
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
Vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.086
PHLDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00606
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.199993
cx45	GeneRIF Biological Term Annotations	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825822
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25282
theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173568
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06798
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392686
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.131765
NCIH2122	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81842
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ofloxacin-3673	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
granulosa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.843286
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38894
secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.123278
infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.225573
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Fever	CTD Gene-Disease Associations	1.0	1.09332
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I9-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.72343
chinese	GeneRIF Biological Term Annotations	1.0	null
PMC9041830-ppat.1010464.s009.xlsx-MAGeCK_MLE_output-STAT1-KO-Gene_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
structure	GeneRIF Biological Term Annotations	1.0	null
Obstetric Labor, Premature	HuGE Navigator Gene-Phenotype Associations	1.0	null
Insulinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.517
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29077
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
Carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.591
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74497
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73765
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-515-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99476
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05465
adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.295132
BRD-K41185648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26209
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64104
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20271
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.069
FBXO48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55953
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34221
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33195
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16404
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584422
BRD-K66870022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18375
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
anovulation	MGI Mouse Phenotype Associations 2023	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25776
LN319	CCLE Cell Line Gene Expression Profiles	1.0	1.44364
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
Charcot-Marie-Tooth disease type 1E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23625
granulosa	GeneRIF Biological Term Annotations	1.0	null
647-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67833
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
19305503-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Perivascular astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K02823077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10444
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
molecules	GeneRIF Biological Term Annotations	1.0	null
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832262
BRD-K71452126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08465
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74482064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13524
SNU886	DepMap CRISPR Gene Dependency	1.0	3.66298
hereditary hemorrhagic telangiectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.256652
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826774
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.18521
Infection Caused By Helicobacter Pylori	DisGeNET Gene-Disease Associations	1.0	null
Heart endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.758673
SARS-CoV_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.24352
a7r5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.905831
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051145
BRD-K05304510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19618
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26722
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	1.49564
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9857
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM53B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98029
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51842
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.47838
CMK	CCLE Cell Line Gene Expression Profiles	1.0	2.65493
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90461
Pancreas-pancreatic stellate cell	Tabula Sapiens Gene-Cell Associations	1.0	0.547249
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.974001
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13811
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50841
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850262
Capillary pericyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.85785
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Vascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
GTEX-WFG7-2426-SM-3GIL2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970196
HUVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.979
Perturb_17409_KO_Kat7_SRP346204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.84124
affecting	GeneRIF Biological Term Annotations	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81938
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
Tracheal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.238
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02755
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
Anal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19015
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00887
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1066
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.12
BRD-K31908823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74835
SCC25	DepMap CRISPR Gene Dependency	1.0	6.00703
BRD-K39237487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66363
developmental process	GO Biological Process Annotations 2015	1.0	null
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.226262
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53799
germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059236
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.50187
GSE233679_5_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186112_1_v_0_med23_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pralidoxime-5383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Arterial endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.199
CRCGN015_HEPG2_48H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09247
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.81647
H2AC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07012
GSE205163,GSE205164_9_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A1L4-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0024
Ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
Calcium regulation in cardiac cells	WikiPathways Pathways 2024	1.0	null
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07914
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.958598
SUV39H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76303
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6200_KO_Firre_SRP076940	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.12626
GTEX-WXYG-0926-SM-3NB2O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12453
cavernous hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.430017
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09577
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36322
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.47799
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985118
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4127
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308251
carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054837
pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
endothelium	GeneRIF Biological Term Annotations	1.0	null
connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191745
myocardial	GeneRIF Biological Term Annotations	1.0	null
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	2.56316
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
finland	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01399
H357	DepMap CRISPR Gene Dependency	1.0	2.91003
PMC5512555__F3	PFOCR Pathway Figure Associations 2024	1.0	null
ARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74575
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
cancer	Phosphosite Textmining Biological Term Annotations	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11542
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.862036
primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222699
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K76922696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82303
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11907
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49886
nisoxetine-5091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3254
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89372
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096509
japanese	GeneRIF Biological Term Annotations	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69689
GSE192689_0_v_2_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
alter	GeneRIF Biological Term Annotations	1.0	null
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08353229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05281
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.087002
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944032
RUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61041
first	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VH-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5748
VBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55819
ITGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9817
lymphedema-distichiasis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.352
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14752
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06911
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.3532
Prestwick-664-4275	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916807
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79444
cx43expressing	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21891
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12659
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065601
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5511
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69445
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858812
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50796
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041009
BRD-K50710005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06017
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
GTEX-OXRK-0326-SM-3NB3R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30531
High endothelial venule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59219
Endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.035
SFXN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08089
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32877
Spleen	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77796
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1478
Tunica externa vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.405
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.558457
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22066
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
telenzepine-5096	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04332
BRD-K51050934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09352
atherogenesis	GeneRIF Biological Term Annotations	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874029
IHF-DNA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.135
ICAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89788
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978472
bicuculline-2139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hypothermia	CTD Gene-Disease Associations	1.0	1.02971
gap	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18315
NCIH510	DepMap CRISPR Gene Dependency	1.0	2.73479
junction	GeneRIF Biological Term Annotations	1.0	null
ACAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.069
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.471208
GTEX-XQ8I-1426-SM-4BOPW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37961
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24676
BRD-K87404495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.95406
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054409
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06353
DPF2_02_14	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.848
Capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.604
blood-lymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98583
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49775
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10364
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254239
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12791
BRD-K66700691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84719
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
Necrosis	CTD Gene-Disease Associations	1.0	2.13403
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01011
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DJM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.68655
GTEX-XOTO-0426-SM-4B66A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995626
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07558
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.524771
BRD-K48389907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21982
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6266
JAK2_druginhibition_167_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44156
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2445
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
ZNF853	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9179
voltageclamp	GeneRIF Biological Term Annotations	1.0	null
BRD-K88988134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79518
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.44382
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
Lung endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
SF126	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05143
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04747
pirlindole-3140	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01293
UPCISCC152	DepMap CRISPR Gene Dependency	1.0	3.80086
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22831
aorta thoracica smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31777
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.09436
keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08056
PIGF_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.792293
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82989
Sarcoma_SARC_TCGA-DX-A6YZ-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41737
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
flunixin-4273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17219
Perturb_18607_Mut_Chek1_SRP299085	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.97472
KMS12BM	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.31511
KE37	DepMap CRISPR Gene Dependency	1.0	2.8156
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01195
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96311
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
gap junction	GO Cellular Component Annotations 2023	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Caveola	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.362
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4344-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
BRD-K62460895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23704
BRD-K54042694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53384
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE235701,GSE261434_2_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848012
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57268
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04022
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4803
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2061
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75089
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.655
Peripheral artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040245
BRD-K27228812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31659
BRD-K73581966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49937
BRD-K84090286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71327
BRD-K38073091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53347
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4905-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63189715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17531
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91101
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.788964
hemodynamically	GeneRIF Biological Term Annotations	1.0	null
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44036
stroke	GeneRIF Biological Term Annotations	1.0	null
type	GeneRIF Biological Term Annotations	1.0	null
BRD-K55895855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18076
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.68354
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03686
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06437
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09511
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55813
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-8_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850262
Venous endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.866
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39027
Brain Ischemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
NOMO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.26148
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K52735829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05485
IFNLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61181
Ca<sup>2+</sup>	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2715-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46854
Erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.112
Microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.737
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.54014
Juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
ACAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29499
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
dispensable	GeneRIF Biological Term Annotations	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923124
GSE205163,GSE205164_3_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14613
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38247
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11529
HCC1954	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00892
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835948
ZNF331	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.999924
microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.859
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43334
arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.21955
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERCC6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68397
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33345
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07649
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33262
diabetic	GeneRIF Biological Term Annotations	1.0	null
Carotid Artery Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99643
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2467-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
obesity	GeneRIF Biological Term Annotations	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45852
FAM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84378
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873025
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59491
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22001
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.715683
BRD-K04087396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34089
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.10142
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
PMC12697342-jem_20250471_tables3.xlsx-large_int_SM-ILF_5_CXCL10-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66208
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
benzocaine-2167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fasting	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
hepatopulmonary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.434148
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
CRCGN015_MCF10A.TP53.M_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0248
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978659
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88918
after	GeneRIF Biological Term Annotations	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
suggested	GeneRIF Biological Term Annotations	1.0	null
KKU100	DepMap CRISPR Gene Dependency	1.0	4.1998
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29779
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57867
Prostate-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	1.01433
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905116
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.86436
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.563017
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.6802
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46531
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell-cell junction assembly	GO Biological Process Annotations 2015	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166167
BICR22	DepMap CRISPR Gene Dependency	1.0	2.36408
Tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.034
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.65145
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865919
BRD-K81925504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06778
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76157
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15363
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834064
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A6K9-06A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2501
BRD-K66577743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15547
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04188
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24473
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7254-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC4	DepMap CRISPR Gene Dependency	1.0	2.01739
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068516
PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101331
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.938777
BRD-K48714854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19804
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90679
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57156
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary lymphedema I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042248
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	1.0905
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83259
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7787
Anorexia	CTD Gene-Disease Associations	1.0	1.26886
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.25167
786	BioGPS Cell Line Gene Expression Profiles	1.0	0.839704
GTEX-OXRN-1426-SM-3LK5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22094
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05788
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1702
IDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21446
individuals	GeneRIF Biological Term Annotations	1.0	null
azacitidine-3348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K48717228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07337
aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.792709
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32518
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22221
enos	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192741
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59968
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMOE-2	GDSC Cell Line Gene Expression Profiles	1.0	3.48963
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE77108_3_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
enilconazole-6518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6991
VPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90708
ASH2L	ChEA Transcription Factor Targets	1.0	null
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00549
vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.677395
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841218
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
three	GeneRIF Biological Term Annotations	1.0	null
BRD-K22071228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13147
Aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.332
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82697
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.6215
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998824
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17605
Epstein-Barr Virus_Akata BL clone-4hr starve_None_GSE19761	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64148
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	224.511
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31455
desoxycortone-6476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.62357
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04287
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.249
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04592
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.949875
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876645
lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174093
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323144
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858898
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845054
human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306083
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36314
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.164866
whether	GeneRIF Biological Term Annotations	1.0	null
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97667
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02774
TBP	ENCODE Transcription Factor Targets	1.0	null
BCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47916
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
orlistat-6415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.5582
MKN45	DepMap CRISPR Gene Dependency	1.0	2.20972
Prostate adenocarcinoma_PRAD_TCGA-CH-5754-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.437
BRD-K58846294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25562
BRD-K42363982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68598
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911425
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978844
responder	GeneRIF Biological Term Annotations	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31522
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21432
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06331
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.497266
Clouston syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.023
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE-296	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42507
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917738
BRD-K16727544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43113
GSE233679_14_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94197
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62029
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.4871
haloperidol-5604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SL-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07737
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44361
BRD-K11487484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51735
juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.823175
BRD-K63102090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95584
BRD-K15879529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26715
BRD-K96431636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31746
Interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
ACIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91029
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061434
BRD-K92565319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16722
formation	GeneRIF Biological Term Annotations	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31097
HL60	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.67063
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22579
Sarcoma_SARC_TCGA-MB-A8JK-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Palmoplantar keratoderma and congenital alopecia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.024
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04068
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2738
clot	GeneRIF Biological Term Annotations	1.0	null
divalent metal ion transport	GO Biological Process Annotations 2015	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal ovulation	MPO Gene-Phenotype Associations	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Schmidt-Lanterman incisure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06279388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34295
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043445
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
Perturb_8606_KO_Mir132/212_SRP064164	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.57727
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.20868
RERFGC1B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19846
Endothelial progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35704
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62516
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35477
chlortalidone-3198	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53050301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00873
hsa-miR-3120-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52159
mesenteric	GeneRIF Biological Term Annotations	1.0	null
Extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.377
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939703
Saphenous vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
rubella	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.196779
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68823900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5481
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.533
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.128
GSE183271_4_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
blood	Phosphosite Textmining Biological Term Annotations	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16212
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3456
tumour	GeneRIF Biological Term Annotations	1.0	null
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065688
Heart-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.897141
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
either	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847229
BRD-K49443464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.044
BRD-K19089958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1316
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
tracheal smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.359664
FKBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59126
Jugular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
JHU029	DepMap CRISPR Gene Dependency	1.0	2.70692
dextro-looped transposition of the great arteries	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35264
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32912
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972597
ERA-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.48299
HDAC1	ENCODE Transcription Factor Targets	1.0	null
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04751
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	0.845556
Myosin phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7805
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4818-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bretylium tosilate-3057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.093
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937768
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dense core granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.67
anabasine-6074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
transfer	GeneRIF Biological Term Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
EYA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46325
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.974
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35677
BRD-K97237010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08526
Right atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
Rectum adenocarcinoma_READ_TCGA-F5-6864-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
death	GeneRIF Biological Term Annotations	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.296571
BRD-K01225799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29049
haloperidol-2704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A2058	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.4091
Pruritus	CTD Gene-Disease Associations	1.0	1.27875
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.929983
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825133
coelom	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099058
BRD-K34264024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.109
peripheral	GeneRIF Biological Term Annotations	1.0	null
16618722-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
PPARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38089
ST6GALNAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05547
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69808
Metaphase plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.17883
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.04237
renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33965
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-3.35797
BRD-K90887068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06505
Capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.145
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30111
Prostate gland_CT2_endothelial cell of artery	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.891308
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02481
hsa-miR-4533	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
valproic acid_homo sapiens_gpl6244_gse23909	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell junction organization	GO Biological Process Annotations 2015	1.0	null
GTEX-XPVG-2726-SM-4B66W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41309
aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.792293
umbilical vein endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.942645
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.30292
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51408
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21969
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133857
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0478
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79393
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4691
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7721
Hemorrhagic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79022
channel	GeneRIF Biological Term Annotations	1.0	null
LRATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90857
BRD-K71089225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47317
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2655
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I4-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.882897
ATF3_02_54	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.74416
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9386
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34845
PKIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75197
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
ZNF395_02_69	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.64386
BRD-K49103797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0821
BRD-K17285234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4409
chr1_34837607_T_C_b38	GTEx eQTL 2025	1.0	1.04092
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22992
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET2	CCLE Cell Line Gene Expression Profiles	1.0	2.37713
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58907
population	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13319
BRD-K56868780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74073
CD47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08757
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48484
benzthiazide-3329	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PIK3CD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26705
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98237
BRD-K19118372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58512
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922056
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106102
BRD-A57762296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6741
ANKRD49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84696
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58088
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K76980944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58437
BRD-K24727463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09383
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05906
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15832
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.913017
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60337
ahr_19454665_epidermal_langerhans_cell_lof_mouse_gpl339_gds3575	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.11274
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ureteral obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.348246
VM-CUB-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6383
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33175
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
Drug Eruptions	CTD Gene-Disease Associations	1.0	1.07482
gap	GeneRIF Biological Term Annotations	1.0	null
BRD-K86935536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42238
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26872
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01726
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PKN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049952
platelets	GeneRIF Biological Term Annotations	1.0	null
BRD-K53802078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05401
Corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06676
CRCGN008_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44855
BRD-K20987582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11141
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
Lung adenocarcinoma_LUAD_TCGA-38-7271-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW480	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.20945
estradiol_homo sapiens_gpl570_gse29881	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14551
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19373
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33427
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.93595
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076012
BRD-K77892726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11428
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.56135
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48641
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
cefaclor-2483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56357490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73744
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.126849
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320591
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K66955555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19356
Arterial blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
BRD-K41798816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03058
gap junction channel activity	GO Molecular Function Annotations 2025	1.0	null
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08123
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20993
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33015
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
much	GeneRIF Biological Term Annotations	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.8671
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	3.77212
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
women	GeneRIF Biological Term Annotations	1.0	null
pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361155
HEL	GDSC Cell Line Gene Expression Profiles	1.0	2.45802
Oculodentodigital dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.704
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78699
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04303
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3065
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869705
CRCGN009_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03472
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22171
BRD-K89423851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67821
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06825
Perianth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
PMC4783780__F8	PFOCR Pathway Figure Associations 2023	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
NCIH322	DepMap CRISPR Gene Dependency	1.0	3.27795
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40651
extravillous trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
sulfasalazine-5446	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906032
g894t	GeneRIF Biological Term Annotations	1.0	null
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34273
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17934
Ovarian Infertility Genes(Mus musculus)	WikiPathways Pathways 2014	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049767
calcium ion transport	GO Biological Process Annotations 2015	1.0	null
MARVELD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19434
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.119
16455954-Table1	GeneSigDB Published Gene Signatures	1.0	null
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tropine-6147	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04864
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20437
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1117
BRD-K89324382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46426
BRD-K52245873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20329
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.2772
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05646
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89994
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066151
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895828
thrombus	GeneRIF Biological Term Annotations	1.0	null
tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.694946
Perturb_4230_KO_Erg/Fli1_SRP402906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.376
significant	GeneRIF Biological Term Annotations	1.0	null
Renal Insufficiency, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.157719
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.13793
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33699
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69285
LN319	DepMap CRISPR Gene Dependency	1.0	3.55648
Vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.23
Apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.643
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03864
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44567
metixene-3313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
acute coronary syndrome;	GAD Gene-Disease Associations	1.0	null
Perivitelline space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.504
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955647
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10533
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895787
Left ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
tridihexethyl-5067	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.74556
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.945531
Vohwinkel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.956
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56517
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscle-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	3.81179
18288381-Table4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XUJ4-2826-SM-4BOQ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0183
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
Cerebrovascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958203
reproduction	GAD High Level Gene-Disease Associations	1.0	0.295739
BRD-K66207462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48595
mediated	GeneRIF Biological Term Annotations	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03247
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
NACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7458
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925845
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80451
Asymptomatic Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46165
BRD-K82662168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09361
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15483
Umbilical artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.002
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hyperuricemia	DisGeNET Gene-Disease Associations	1.0	null
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20408
connexins	GeneRIF Biological Term Annotations	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.75895
cerebral infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.248203
BRD-K69536411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19707
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45143
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51225
BRD-K51278788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01872
Pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
BRD-K57502201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.74318
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94275
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65671
Posterior cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
inner CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.88634
Perturb_7200_KD_DHX9_SRP080966	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.40045
SW13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.915055
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53744
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12160862-ijbsv21p3573s2.xlsx-Table_S12-Supplementary_Table_S12_Differentially_Expressed_Genes_in_fibroblast_grouped_by_SOX11_expression_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
han	GeneRIF Biological Term Annotations	1.0	null
BRD-A59683007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57857
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46465
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240216
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
GSE206870,GSE206872_1_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
endothelial	GeneRIF Biological Term Annotations	1.0	null
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7047
PTGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53292
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12227
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PF382	DepMap CRISPR Gene Dependency	1.0	3.35776
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABHD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47428
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49328
peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.21522
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22045
LU-99A	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47598
BRD-A20182314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32282
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12538
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4856-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.233
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67931
UT7	CCLE Cell Line Gene Expression Profiles	1.0	1.90628
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99517
limit	GeneRIF Biological Term Annotations	1.0	null
detect	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954591
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.925
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.26006
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3349
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42474
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91772
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
connexon complex	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4530	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
undecane	CTD Gene-Chemical Interactions	1.0	null
Renal Insufficiency	CTD Gene-Disease Associations	1.0	1.24997
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
restenosis	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03751
Vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.006
shown	GeneRIF Biological Term Annotations	1.0	null
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57143
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11914
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865129
mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.137109
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.52
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59241
Aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071729
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20718
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.606933
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05817
terminus	GeneRIF Biological Term Annotations	1.0	null
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988385
channels	GeneRIF Biological Term Annotations	1.0	null
BRD-K25330450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81797
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57952
organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Superior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08268
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5792
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26346
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51248
Gap junction protein, cysteine-rich domain	InterPro Predicted Protein Domain Annotations	1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.5551
cell communication	KEGG Pathways	1.0	null
Hepatitis, Autoimmune_Hepatic Tissue_GSE867	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.27477
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
Pulmonary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47803
pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.377245
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.931
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17792
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.269
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
carotid	GeneRIF Biological Term Annotations	1.0	null
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
impaired ovarian folliculogenesis	MPO Gene-Phenotype Associations	1.0	null
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47578
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
CIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32206
young	GeneRIF Biological Term Annotations	1.0	null
control	GeneRIF Biological Term Annotations	1.0	null
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5293
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00818
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09199
GSE95685_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
BRD-K06251362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67016
FZD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80795
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858422
BRD-K88200581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40107
GSE142684_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARGC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55353
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2758
Adult liver stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05575
heterogeneity	GeneRIF Biological Term Annotations	1.0	null
procyclidine-4817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DNAJC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97685
cell-cell junction organization	GO Biological Process Annotations 2015	1.0	null
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828027
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07933
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070378
PMC7403357-41598_2020_69735_MOESM4_ESM.xlsx-24h_AV_Genes_Sig-FOSL1_is_a_novel_mediator_of_endotoxin_lipopolysaccharide-induced_pulmonary_angiogenic_signaling_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.84916
Vasculature-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	5.04562
NUDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79989
cefoxitin-6796	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05471809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45386
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nabumetone-3108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5121-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.41721
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14302
Cardiac muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.871
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27857
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06417
Coronary Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
Artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.511
Pars recta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
BRD-K73075421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4716
BRD-K56431031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26196
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8708
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23176
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Apical tubulobulbar complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52129
BRD-K41562445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25981
CRCGN010_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93438
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.4855
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K43918778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.08747
epithelium development	GO Biological Process Annotations 2015	1.0	null
Vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.009
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7566
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231206
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23844
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66712
SKNEP1	DepMap CRISPR Gene Dependency	1.0	2.22066
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855955
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040901
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879874
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	1.0	1.6286
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896863
Weight Loss	CTD Gene-Disease Associations	1.0	1.76092
BRD-K78886448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23245
response to pain	GO Biological Process Annotations 2015	1.0	null
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46797
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40818
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0873
norcyclobenzaprine-2469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cholestasis	CTD Gene-Disease Associations	1.0	1.37789
keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352969
pylori	GeneRIF Biological Term Annotations	1.0	null
JK1	CCLE Cell Line Gene Expression Profiles	1.0	1.79702
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1519
BRD-K94062017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0523
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45881
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gating	GeneRIF Biological Term Annotations	1.0	null
BRD-K78995236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06351
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
breast-neoplasms	Phosphosite Textmining Biological Term Annotations	1.0	null
BAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
ZCCHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96838
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075509
parolfactory gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.851674
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348148
HEYA8	Achilles Cell Line Gene Essentiality Profiles	1.0	1.69571
Acute Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.712795
BRD-K37949240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20176
BRD-K37770214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96162
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K00502656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13871
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11792
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06687
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57315740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48503
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23328
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03253
TSACC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2851
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29589
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52045
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17141
JURLMK1	CCLE Cell Line Gene CNV Profiles	1.0	2.06486
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946948
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8616
hsa-miR-4478	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
A7r5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP36L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13991
Perturb_4306_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.29283
resulting	GeneRIF Biological Term Annotations	1.0	null
Mdr2_KO_GDS1990_286_mouse_Livers of 12 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07928
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98469
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65668
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
sizes	GeneRIF Biological Term Annotations	1.0	null
BRD-K87939000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58714
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00918
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.567
prednisolone-2393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
Gap junction assembly	Reactome Pathways 2014	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Heart ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.565
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27471
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32497
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18713
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57754
hsa-miR-4419b	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
H4C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66766
Endothelial cell_Eye_Human	CellMarker Gene-Cell Type Associations	1.0	null
Saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.484
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.40832
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.25463
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.528388
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44996
Kidney Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Stroke	HuGE Navigator Gene-Phenotype Associations	1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
GSE193027_1_v_0_krt19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.09011
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.95131
chenodeoxycholic acid-7433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hypb_Deficiency_GDS3641_522_mouse_Yolk sac from E9 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Coronary Artery Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867135
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46259
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962955
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.86671
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58487
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22265
GTEX-X261-0226-SM-3NMD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39057
Proteinuria	HuGE Navigator Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4170-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53936012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26683
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970986
Endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.539
chorioamnionitis; fetal membranes, premature rupture; infection of amniotic sac and membranes; obstetric labor, premature; pre-eclampsia; premature birth	GAD Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65778
Coronary Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.949663
BRD-K14211116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90914
ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.30342
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058467
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951619
artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.747927
markers	GeneRIF Biological Term Annotations	1.0	null
RPMI-8402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
taiwanese	GeneRIF Biological Term Annotations	1.0	null
GSK3A_KD_GDS4305_184_human_U937 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.09844
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46873
Smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.384
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59431
Blastocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
HCC70	DepMap CRISPR Gene Dependency	1.0	2.5454
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5262-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Granulosa cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
CTSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67338
BRD-K53816426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05638
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.726
imt	GeneRIF Biological Term Annotations	1.0	null
BRD-K01772946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08281
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.45638
BRD-K11477112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47965
CNOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87541
BRD-K96619480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27961
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7847
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851162
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
Microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97115
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20123
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
AKT1_knockdown_123_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.60897
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.899537
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Connexin	InterPro Predicted Protein Domain Annotations	1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33687
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.47634
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.628457
sulfafurazole-3218	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pacemaker cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38326
BRD-K75506133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12035
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
insulinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.783526
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5402
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84758
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65897
mixed germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170544
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Aortic valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
BRD-K57556489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04752
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58334
abnormal meiosis	MPO Gene-Phenotype Associations	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.51506
plaques	GeneRIF Biological Term Annotations	1.0	null
BRD-K20661169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19229
Stalk cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
Lung endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
binding	GO Molecular Function Annotations 2015	1.0	null
trioxysalen-5736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hepatic vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.222822
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.383
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44585
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75807319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86937
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3038
urapidil-6455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alverine-2273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hypertension; obesity	GAD Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.650642
Arteriovenous malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
c1019t	GeneRIF Biological Term Annotations	1.0	null
gliclazide-5089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.445
PHA-00851261E-4333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29455
PMC12697342-jem_20250471_tables3.xlsx-large_int_SM-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58935
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40667
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.86953
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22167
SLC25A22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72227
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.62058
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.83485
ri1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54159
BRD-A29371732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10199
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01312
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15162
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981472
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33629
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Vasculature	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.306
17009876-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
Perturb_9142_OE_TBXA2R_SRP252589	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
snp	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75253
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
Dorsal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.578
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99739
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86489
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.879014
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67655
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.13041
BRD-K56799639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21649
Dendrite cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40643
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11267
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	0.873759
BRD-K56588599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62408
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.623
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39027
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41498330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92359
BRD-K96663576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70534
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8271
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28454
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09076
Perturb_8484_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.22338
Blood clot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14782
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54352
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.07625
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61152
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.950258
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03188
BRD-A77440546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29467
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sulfaquinoxaline-2528	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
arsenic trioxide	CTD Gene-Chemical Interactions	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53296
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
male	GeneRIF Biological Term Annotations	1.0	null
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16652
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18914
FUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90987
Adenocarcinoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22415
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.83007
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GIPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77349
BRD-K11095218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03123
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.97222
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
Perturb_3996_KD_ADGRG1_SRP260905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5738
GTEX-S4UY-0226-SM-3K2AP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31148
Perturb_3195_KO_Poldip2_SRP302743	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.9467
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47593
ozagrel-3503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83976
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
Mural cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.895
LIVF001-023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0465
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.1079
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08295
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49076
19286929-SuppTable2h	GeneSigDB Published Gene Signatures	1.0	null
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8673
SCS214	DepMap CRISPR Gene Dependency	1.0	3.01762
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34597
ethotoin-4366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.325
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
PMC4783780__F8	PFOCR Pathway Figure Associations 2024	1.0	null
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.042
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell-cell junction assembly	GO Biological Process Annotations 2023	1.0	null
Prestwick-981-7464	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05017
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041235
blepharophimosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.468063
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.86733
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04406
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50691
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041347
BRD-K97485863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19065
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.872146
abnormal oogenesis	MPO Gene-Phenotype Associations	1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.9391
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suggests	GeneRIF Biological Term Annotations	1.0	null
BRD-K89668690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58429
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987563
carbenoxolone	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35401
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45471346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83455
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09696
BRD-K24343968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06707
Bone matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877773
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8596-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell junction assembly	GO Biological Process Annotations 2023	1.0	null
ADH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3328
thrombi	GeneRIF Biological Term Annotations	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8674
GTEX-QLQ7-1926-SM-2S1R6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828337
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918908
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48121
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68923
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97362312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05498
KU812	CCLE Cell Line Gene Expression Profiles	1.0	1.67561
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059541
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79613
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39149
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8958
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99677
CP-690334-01-4383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ischemic	GeneRIF Biological Term Annotations	1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.329
metal ion transport	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20761
AG-013608-6395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cutaneous mastocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.207912
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98995
GSE231648_0_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
testosterone-5271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYTH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28421
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91671
properties	GeneRIF Biological Term Annotations	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.893921
BRD-K24640918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25454
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932559
cell junction assembly	GO Biological Process Annotations 2025	1.0	null
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1904
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
cytoplasmic	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K04635516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25244
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52694
A388	DepMap CRISPR Gene Dependency	1.0	2.67316
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
infertility	MPO Gene-Phenotype Associations	1.0	null
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
modulate	GeneRIF Biological Term Annotations	1.0	null
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
Mammary Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.03271
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27904
small	GeneRIF Biological Term Annotations	1.0	null
CRCGN008_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03795
cell junction assembly	GO Biological Process Annotations 2015	1.0	null
RPP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24578
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871928
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141107
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23012
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.591
coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.874919
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829947
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.935656
Myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	1.53917
spectinomycin-4187	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OVKATE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70773
gja4	GeneRIF Biological Term Annotations	1.0	null
mastocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.097866
nimodipine-5421	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K35788497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18511
Uterine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10843
BRD-K10704442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62486
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64332
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835021
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39526
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
explained	GeneRIF Biological Term Annotations	1.0	null
Prostate gland_CT2_endothelial cell of artery	HuBMAP ASCT+B Annotations	1.0	null
DLX5_Deficiency_GDS4443_355_mouse_E10 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
16618722-Table1	GeneSigDB Published Gene Signatures	1.0	null
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11009
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.871791
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31510624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04808
GPAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30707
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5378-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16683
BRD-K81288338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43393
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Metabolic Syndrome X	HuGE Navigator Gene-Phenotype Associations	1.0	null
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	1.38741
interleukin-35 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166405
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885967
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62327
16886892-Table2	GeneSigDB Published Gene Signatures	1.0	null
11884566-Table4	GeneSigDB Published Gene Signatures	1.0	null
Femoral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
voltage	GeneRIF Biological Term Annotations	1.0	null
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_12Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65729
Tongue-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0738508
Gap junction trafficking and regulation	Reactome Pathways 2014	1.0	null
Aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_0_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94896
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56003
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39027
Heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.526
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29591
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.866152
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216528
BRD-K12918607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75692
exposure	Phosphosite Textmining Biological Term Annotations	1.0	null
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82037
17571080-SuppTable2c	GeneSigDB Published Gene Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03599607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60757
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81596
Internal carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
Glomerulonephritis, IGA	HuGE Navigator Gene-Phenotype Associations	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971975
TXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33481
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978168
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
inhibits	GeneRIF Biological Term Annotations	1.0	null
bemegride-3051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
46 XX gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
Coronary Restenosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.28364
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074554
Bacterial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
CCZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23995
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17639
abnormal ovarian follicle morphology	MPO Gene-Phenotype Associations	1.0	null
16488994-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40949
BECKER	DepMap CRISPR Gene Dependency	1.0	2.6503
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71717
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20069
iranian	GeneRIF Biological Term Annotations	1.0	null
Basal ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.802
Perturb_17724_KD_MED23_SRP342076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281776
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
Skin-muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.942342
ANKRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34717
Premature Birth	HuGE Navigator Gene-Phenotype Associations	1.0	null
DUSP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09111
TRIFLUPERIDOL-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90492
infection	GeneRIF Biological Term Annotations	1.0	null
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
trans-Golgi network membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9804
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33221
Renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935987
BRD-K40485332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12375
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.54217
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86184
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.31737
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
related	GeneRIF Biological Term Annotations	1.0	null
RASGRF1_KD_GDS2816_287_human_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0571
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-331-PGR_PGR	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
Atrioventricular block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
risk	GeneRIF Biological Term Annotations	1.0	null
ZC3HC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84653
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.931
Neoplasm Invasiveness	CTD Gene-Disease Associations	1.0	1.22948
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.663578
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.298214
Hyperhomocysteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061703
BRD-K99125195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15141
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5441
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87841
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.69318
umbilical vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.544417
endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459918
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19075
GSE221004_1_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896733
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17413
BRD-K79712504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44496
Sarcoma_SARC_TCGA-DX-A23T-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K44955380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21704
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ketoprofen-2354	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
advanced	GeneRIF Biological Term Annotations	1.0	null
Connexin complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K44548010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38623
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18633
effects	GeneRIF Biological Term Annotations	1.0	null
BRD-K28455914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28951
LS513	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0327
VMRCRCW	DepMap CRISPR Gene Dependency	1.0	5.28231
DAGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64452
SPAST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85933
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894824
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058242
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
MPV17L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60451
MRPL58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54935
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44361
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
PDPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08141
future	GeneRIF Biological Term Annotations	1.0	null
insulinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692085
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71133
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
key	GeneRIF Biological Term Annotations	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910903
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059269
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25839
GTEX-XUZC-1826-SM-4BRVO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58721
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831663
CTBP1_02_41	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.51096
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
brain ischemia; cardiovascular diseases; coronary disease; stroke	GAD Gene-Disease Associations	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Aortic endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.045
BRD-K22797212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06197
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36106
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04479
Mural cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF717	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52355
NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12867126-NIHMS2139346-supplement-Supplementary_Table_S1.pdf-5-SOX17_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44102
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87941
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35858
BRD-K65828139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56964
HECTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94301
connexin37	GeneRIF Biological Term Annotations	1.0	null
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09492
EZH2	ENCODE Transcription Factor Targets	1.0	null
atherosclerosis	GAD Gene-Disease Associations	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
Inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.25825
GSE196535_1_v_0_gpr151_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
connexin complex	GO Cellular Component Annotations 2025	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
12738660-TableS3	GeneSigDB Published Gene Signatures	1.0	null
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81683
BRD-K42899345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79694
bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090173
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Calcium Regulation in the Cardiac Cell(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
potentially	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69808
CRCGN015_MCF10A_48H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08471
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.836
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatic primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
Plasma membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.401
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	2.88009
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.041
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51023
Lens epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37009
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051181
lamellar body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.844237
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Chorioamnionitis	HuGE Navigator Gene-Phenotype Associations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Trachea-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.294456
BRD-K16264250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68022
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7637
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35415
polymorphism	GeneRIF Biological Term Annotations	1.0	null
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042468
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01471
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.84902
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32479
Perturb_9150_KD_WTAP_SRP307037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.6159
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
abnormal female reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94692
ERBB3_drugactivation_70_GSE21463	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.6341
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18894
Umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
BRD-K00401259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69443
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52963
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.14166
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07528
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61544
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	2.12254
fetus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	2.15381
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83971
BRD-K53491881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06822
hemorrhagic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.119587
infarction	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4643-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEx Nerve 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-9.58708
BRAF_knockdown_193_GSE5481	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.79699
Lateral vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
carbarsone-4110	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195981
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877773
Rabies CVS-11_7day-Brain_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.89663
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13284
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.10636
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868587
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02311
BRD-K46839342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16147
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.991981
BRD-K04044480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71177
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4P3-1826-SM-3K2AL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17213
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney failure, chronic	GAD Gene-Disease Associations	1.0	null
BRD-K81999794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04817
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
Endogenous progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
methyl-salicylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05177
Lymphatic endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.038
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0521
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05875
Allantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
GTF3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10659
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89061
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44713204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08019
BRD-K16838444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34565
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gate	GeneRIF Biological Term Annotations	1.0	null
BRD-K39809702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29811
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128034
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30005
BRD-K74665927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00062
Perturb_10903_KO_Ppp1r3c_SRP019798	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.76054
flufenamic acid	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
BRD-K39224209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13767
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046369
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49202
BRD-K12862541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5502
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K95343362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08869
myocardial infarct	GAD Gene-Disease Associations	1.0	null
Arterial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
GSE142630_0_v_2_hiltonol_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50779
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
factors	GeneRIF Biological Term Annotations	1.0	null
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36855
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.74276
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092662
umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.207314
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983982
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91575768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02696
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01002
Hereditary hemorrhagic telangiectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
BRD-K05886700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51712
BRD-K70735803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04646
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38484
Gonadal sheath cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856003
ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.630314
Embryonic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
BRD-K05392698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89404
pnpla3	GeneRIF Biological Term Annotations	1.0	null
BRD-K20416270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18893
variation	GeneRIF Biological Term Annotations	1.0	null
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30055
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49644
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.56038
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.759914
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05624
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16982
myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482038
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
prilocaine-3624	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29501
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80017
NCIH2171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52496
SARS-BatSRBD_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.66901
required	GeneRIF Biological Term Annotations	1.0	null
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.33993
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043429
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
predictive	GeneRIF Biological Term Annotations	1.0	null
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13854
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923124
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36572
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062083
Gastritis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.413
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TMEM30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14571
HCC2998	DepMap CRISPR Gene Dependency	1.0	3.51368
Brain Lower Grade Glioma_LGG_TCGA-CS-6667-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91182
gap junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K53548389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57158
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
Acidosis	CTD Gene-Disease Associations	1.0	1.01324
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91737
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16589
Tracheal smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
lymphatic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521223
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.532078
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33116
BRD-K77733130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50588
thioperamide-4675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27348
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33184
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25166
localization	GeneRIF Biological Term Annotations	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
Elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.009
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17118
DAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41067
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25109
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0085
BRD-K93176491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2017
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41478
Insulinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
luteinized	GeneRIF Biological Term Annotations	1.0	null
connexin complex	GO Cellular Component Annotations 2023	1.0	null
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.231102
BRD-K11188962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33457
aorta endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00196
Uterus-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	0.600821
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79762
AMOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68714
establishment of localization	GO Biological Process Annotations 2015	1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	1.50757
GTEX-REY6-0926-SM-48FDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837647
BRD-K71870778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07804
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50396
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48691
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
electrical	GeneRIF Biological Term Annotations	1.0	null
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19222
GTEx Nerve 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-3.73043
Heart endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85169
Cheek pouch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.361
BRD-K32124229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00684
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02582
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47705
RFWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39708
hcs	GeneRIF Biological Term Annotations	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04191
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
platelet	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SELENOI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24626
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.305
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36319
Acute Chest Syndrome	DisGeNET Gene-Disease Associations	1.0	null
capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393442
DCAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01123
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872382
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93991
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6541
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32632
multicellular organismal response to stress	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859683
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58747
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vasculature	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.98282
BRD-K01749472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0998
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
RPP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03051
FLI1	ChEA Transcription Factor Targets	1.0	null
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96081
NCCIT	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32483
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36834
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952413
BRD-K01367715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54822
U87MG	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05674
Stomach Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3939
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32214429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23603
SENP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58966
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76019
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47122
BRD-K70941721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09959
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.079
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OPRK1	Pathway Commons Protein-Protein Interactions	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00317
extraglomerular mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.885862
BRD-K63624341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77502
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.37987
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03381
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74921
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51861
Lung adenocarcinoma_LUAD_TCGA-38-4627-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832307
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02197
PTPN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35264
SR	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03606
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068815
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055869
Perturb_9163_KD_Shp2_SRP351122	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.45446
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.458
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
hypertension	GAD Gene-Disease Associations	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
nterminus	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6401-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29119
17192395-Table1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24704
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GPRASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78671
DENND6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52152
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74384
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44746
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77433
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	180.727
blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.088212
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32152
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
portal hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279367
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36073
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2354
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74242
hepatic	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K87754766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77174
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.747
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074844
Perturb_7914_KD_TOP1MT_SRP372079	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.26183
CRCGN014_HEPG2_3H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1217
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048087
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21896
CCF-STTG1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76956
Lung adenocarcinoma_LUAD_TCGA-55-8299-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2374
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.23424
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.247852
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901403
DANG	CCLE Cell Line Gene Expression Profiles	1.0	1.55727
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.72681
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.38032
Colonic Neoplasms	CTD Gene-Disease Associations	1.0	1.28641
CA2+	DGIdb Drug Targets 2026	1.0	0.322756
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06512
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
abdominal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103059
LRRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67598
stratum basale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190939
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0384
Proteinuria	CTD Gene-Disease Associations	1.0	1.70285
SNRK_overexpression_127_GSE30185	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.95858
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
sulfamethizole-6099	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1539	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.27875
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
abnormal reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
RT112	DepMap CRISPR Gene Dependency	1.0	2.05646
GSE211128_7_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6727
TYKNU	CCLE Cell Line Gene CNV Profiles	1.0	1.51006
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-1926-SM-3NB25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853492
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057211
Lymph vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.099
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.13369
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
BRD-K47349976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57065
specific	GeneRIF Biological Term Annotations	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
source	GeneRIF Biological Term Annotations	1.0	null
Cell wall-bounded periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
CRCGN015_MCF10A.WT.HP_24H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39309
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
fluocinonide-4314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43182
etilefrine-4415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cerebrovascular Accident	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE211128_2_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19799
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00732
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959525
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.192
smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.4283
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66717
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99052
determination	GeneRIF Biological Term Annotations	1.0	null
hemichannel	GeneRIF Biological Term Annotations	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H838	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72991
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9588
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3236
Perturb_17759_KO_Lin9_SRP221087	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K11636255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61299
dc96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20651
HSC1	DepMap CRISPR Gene Dependency	1.0	2.64246
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8711
arterial endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.62991
Arsenic	CTD Gene-Chemical Interactions	1.0	null
arterial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721988
BRD-K34382498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0173
localization	GO Biological Process Annotations 2015	1.0	null
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30858
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-UJHI-1326-SM-4IHJO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922147
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77541
DUSP1_Deficiency_GDS1606_765_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K80495774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15271
endothelium development	GO Biological Process Annotations 2015	1.0	null
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4316
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15557
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6619
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.856334
Borderline Hypertension	DisGeNET Gene-Disease Associations	1.0	null
NCI-H345	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44291
Perturb_14232_Mut_Dpagt1_SRP230444	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.2053
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02392990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14459
ramipril-3572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34208
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.103
ZNF285	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31446
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10533
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.41884
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.829
within	GeneRIF Biological Term Annotations	1.0	null
cell-cell junction organization	GO Biological Process Annotations 2023	1.0	null
C19orf53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50049
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lewis lung carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00626
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02485
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13344
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79562
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.76884
female infertility	MPO Gene-Phenotype Associations	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.904978
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054112
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63318
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
MRPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4796
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_8_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46675
ECC12	CCLE Cell Line Gene Expression Profiles	1.0	1.75386
PARP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21377
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98194
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13536
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K92241728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5849
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868216
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492182
methanthelinium bromide-6254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99074976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10542
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.8659
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03074
spectinomycin-3327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05417
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Demyelinating Diseases	CTD Gene-Disease Associations	1.0	1.06881
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
Bicellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.702
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.905
selectively	GeneRIF Biological Term Annotations	1.0	null
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45916
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
Ebl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.0306
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28833
BRD-K87191742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88851
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71059
Liver Failure	CTD Gene-Disease Associations	1.0	1.16368
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51241
Polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
BRD-K28057105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42442
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52951
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53877
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.602088
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
GTEX-XQ8I-0526-SM-4BOPS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42225
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59833
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.343
rosiglitazone-1174	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02385
GTEx Thyroid 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-8.65833
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51791
affect	GeneRIF Biological Term Annotations	1.0	null
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
HEC1A	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24146
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.55429
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39802
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54309
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51600962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30323
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3462
BRD-K16641781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49331
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866965
tracheal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196299
BRD-K43872193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71781
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856003
Hypertension	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73562
Nkx-2.5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43517
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83276
nerve-tissue-proteins	Phosphosite Textmining Biological Term Annotations	1.0	null
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4755
KNS81	Achilles Cell Line Gene Essentiality Profiles	1.0	2.53138
Neoplasms	CTD Gene-Disease Associations	1.0	1.50877
A253	DepMap CRISPR Gene Dependency	1.0	2.4797
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
angina, unstable; myocardial infarction; syndrome; unstable angina	GAD Gene-Disease Associations	1.0	null
Aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.135
aminophenazone-6818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
Perturb_7004_Mut_Htt_SRP043967	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.27601
JHOC5	Achilles Cell Line Gene Essentiality Profiles	1.0	1.58556
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922056
coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331927
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33847
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K40102258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03688
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14157
independent	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52C-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.609
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37957
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64109
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Embryonic blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24709
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
15-delta prostaglandin J2-5591	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gap junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Cataract 1 multiple types	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
SMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65643
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K32445732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42514
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56349
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.36645
procaine-5430	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.6214
BRD-K02548315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31589
Ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.199
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37785
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4612
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
Syncytium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.784
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71149
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0215
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21802
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53959
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.965767
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25799
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874905
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71467
ZXDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34383
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glomerular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
PMC11921655-12959_2025_709_MOESM1_ESM.xlsx-MI_related_target-OMIM_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.84
cx43	GeneRIF Biological Term Annotations	1.0	null
Arterial endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.96
SNURF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89246
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234302
GSE220520_5_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59124
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.623051
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44204
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39027
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058068
Vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21015
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.29265
umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192869
BRD-K36713925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32839
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
Perturb_17760_KO_Lin9_SRP221087	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.9805
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.827
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19381
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899694
BRD-K39411863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27583
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971975
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49292348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01709
calcium folinate-2579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ebolavirus(ZEBOV)_3day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.25777
Tunica media vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4870-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.498048
Perturb_17819_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.76298
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6637
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08229
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33277
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13403
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845345
Perturb_8695_KO_Stat1_SRP364338	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838128
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
atherosclerosis	GeneRIF Biological Term Annotations	1.0	null
BRD-K65780164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06564
ovary	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.0662
Juvenile polyposis-hereditary hemorrhagic telangiectasia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13382
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF1_02_81	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.10434
fulvestrant-7534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32877
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09601
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126615
aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221802
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.75843
Heart Diseases	CTD Gene-Disease Associations	1.0	1.33642
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sprout	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.4
BRD-K97682096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05831
Lung Diseases	CTD Gene-Disease Associations	1.0	1.32192
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18377
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62008
Arrhythmias, Cardiac	CTD Gene-Disease Associations	1.0	1.20196
likely	GeneRIF Biological Term Annotations	1.0	null
mimosine-6703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31844
mast cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.245396
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04638
susceptibility	GeneRIF Biological Term Annotations	1.0	null
BRD-K74317118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54114
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42762
NCIH810	CCLE Cell Line Gene Expression Profiles	-1.0	-2.57125
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43733
GTEX-W5WG-1026-SM-4LMIF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21979
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09891
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Arterial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71141
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
H4C9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23481
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14099
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_ATF3_PanPC_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88137
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90617
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084822
lymphatic endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.434906
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.614
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061518
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38714
obesity; vascular diseases	GAD Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953318
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08891
Plasma membrane raft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.369
GSE223008_0_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958284
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239007
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76929
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36273
SR	GDSC Cell Line Gene Expression Profiles	1.0	1.82562
larynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129103
Immature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.548
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.79621
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39675