association	dataset	threshold value	standardized value
BRD-K89260735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16831
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17988
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7819
conjunctival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.260538
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hypomyelinating leukodystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28443
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174617
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62800316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8273
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21053
TYKNU	CCLE Cell Line Gene CNV Profiles	1.0	1.52634
ASPRV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52734
MYC	ChEA Transcription Factor Targets	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66991
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49789
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hearing impairment; hearing loss	GAD Gene-Disease Associations	1.0	null
BRD-K27723822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02256
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93458
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236627
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.580276
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24474
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Junctional membrane complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.984
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07835
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12319
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35698
VA-ES-BJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7941-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
C6 glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0151
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1395
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46761
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
F11R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0751
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13739
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71094
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4998
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968417
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4133
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174383_6_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
symmetrical	GeneRIF Biological Term Annotations	1.0	null
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80041
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.98202
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45185
enlarged spleen	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K92180676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10619
ZNF584	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42517
abnormality of skin adnexa	HPO Gene-Disease Associations	1.0	null
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02666
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POU5F1	ChEA Transcription Factor Targets	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1672
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11208
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.208
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IZ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ahl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38455
CTF1	MotifMap Predicted Transcription Factor Targets	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901622
neoplasm of the skin	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7253-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39531
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82133
abnormality of body height	HPO Gene-Disease Associations	1.0	null
Keratosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
hsa-miR-3175	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0037
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830864
GTEX-S95S-0426-SM-4B64I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919318
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32807
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22682
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
jm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
impaired olfaction	MGI Mouse Phenotype Associations 2023	1.0	null
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57094
GSE98360,GSE98362_1_v_0_uhrf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58286708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31534
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08082
adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.104892
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3823
hypermelanotic macule	HPO Gene-Disease Associations	1.0	null
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.034
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01917
BRD-K10180613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27887
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.35674
hsa-miR-1279	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40676
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.417
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
Mal de Meleda	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.901
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.90507
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69567
Lung squamous cell carcinoma_LUSC_TCGA-66-2780-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M059K	DepMap CRISPR Gene Dependency	1.0	6.50824
Sarcoma_SARC_TCGA-DX-A6YU-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6977
FLO1	DepMap CRISPR Gene Dependency	1.0	2.00268
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40118
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97264
SELENOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80613
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862501
chinese	GeneRIF Biological Term Annotations	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06657
Myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03639
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09577
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.87272
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
TP63_NULL MUTATION_GDS1434_308_mouse_Skin at embryonic age E18.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5664
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81932943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03447
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
medullary hindbrain (medulla)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10827
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07753
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13349
BRD-K48050202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24815
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95791
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.61441
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062931
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87645
Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.405
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04194
BRD-K71472853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31695
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53477
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4723-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10444
hearing impairment	HPO Gene-Disease Associations	1.0	null
Calcium Regulation in the Cardiac Cell(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53069
BRD-K15607890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41304
nuclear lumen	GO Cellular Component Annotations 2023	1.0	null
BRD-K85059356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44456
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.24271
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97213
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SAOS2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73555
BRD-K09655230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14333
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04646
BRD-K20348534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33481
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital symmetric circumferential skin creases 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
BRD-K55623459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42701
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60392
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0817
BRD-K62248885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41016
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54702
cognitive impairment	HPO Gene-Disease Associations	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03905
hsa-miR-4429	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K87929769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27272
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39546
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_KDM5B_22020125	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
hsa-miR-4649-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
interleukin-35 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.487307
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q8-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
octanol	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10643
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60687
thymic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402144
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1106
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25338
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0099
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75913
BRD-K77953978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22547
GSE174383_6_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09506
cutaneous photosensitivity	HPO Gene-Disease Associations	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3283
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	1.49476
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965595
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
generalized hyperkeratosis	HPO Gene-Disease Associations	1.0	null
vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.865577
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01921
Immature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9688
Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65867
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4869-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19436
abnormality of corneal stroma	HPO Gene-Disease Associations	1.0	null
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36719
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54438
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831035
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.431
ChIP_TCF3_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51171
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20672
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01234
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.20454
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41716
CAOV4	CCLE Cell Line Gene Expression Profiles	1.0	1.5832
BRD-K65315551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04258
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6297
BRD-K08996393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29199
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00693
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81007
JUND	ENCODE Transcription Factor Targets	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.324
Cataract 1 multiple types	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
RARG	ChEA Transcription Factor Targets	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91505
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39346
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21469
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24859
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51535
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.9601
Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.42968
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0236
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87869
BRD-K12035825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21169
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24348
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89066
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96731
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67604
Lung squamous cell carcinoma_LUSC_TCGA-85-8481-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59751
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051816
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K86077185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28113
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19706
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18157
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11797
microcephaly	HPO Gene-Disease Associations	1.0	null
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64318
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24927
Perturb_18392_KO_923large_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.64349
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Patchy Palmoplantar Keratoderma	DisGeNET Gene-Disease Associations	1.0	null
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
BRD-K83185986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24656
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.42261
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86648
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91164
Palmoplantar keratoderma-deafness syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.566
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81275
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
only	GeneRIF Biological Term Annotations	1.0	null
PIK3CA_knockdown_182_GSE46869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.19631
neurological system process	GO Biological Process Annotations 2015	1.0	null
CHILD syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18689
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28021686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24852
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09279
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36765
CRCGN009_HEPG2_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46297
abnormal olfaction	MPO Gene-Phenotype Associations	1.0	null
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16401
system process	GO Biological Process Annotations 2015	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7483-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8691
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22257
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23871
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.026
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	3.18145
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
BRD-K32787834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0391
protein complex	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4646-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
HA1E	DepMap CRISPR Gene Dependency	1.0	2.77227
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06547
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053294
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43509
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.933917
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18516
ACT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
el2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6227-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77019
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JJN3	DepMap CRISPR Gene Dependency	1.0	3.60614
Perturb_17261_KD_Prmt7_SRP345507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050298
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.066
SKUT1	DepMap CRISPR Gene Dependency	1.0	2.14926
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06103
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38455
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7187
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.38397
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.154736
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091987
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55309
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
netherton syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.701928
BRD-K32520360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53108
SNU869	DepMap CRISPR Gene Dependency	1.0	2.50462
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60935
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6527
GTEX-WH7G-0926-SM-4LVMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830423
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895919
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.42423
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
BRD-K50247051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06822
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32199
hsa-miR-4499	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
APPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87836
BRD-K40219231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1812
BRD-K03361106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1161
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32502
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A3Y1-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52261313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31164
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1226-SM-4AD4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895359
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88499
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0692
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3377
BRD-K74537058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04033
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16949
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.61215
Perturb_3821_KO_Zfp280c_SRP330880	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73448
hsa-miR-2467-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Oculodentodigital dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.626
Acquired hyperkeratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42824
describe	GeneRIF Biological Term Annotations	1.0	null
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE195559_0_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.29961
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_78_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866831
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13062
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7387
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.61976
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05762
SRY-22984422-TESTIS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
enlarged spleen	MGI Mouse Phenotype Associations 2023	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63562
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_82_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36535
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08634
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15846
sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459145
SH2D3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A60877539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40998
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66592
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36191
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69543
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MT-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24291
CLPP_KO_GDS4791_374_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	1.44735
BRD-K77490065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05171
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43916
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06965
carbenoxolone	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03587
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11402
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964299
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945971
erythrokeratodermia	GeneRIF Biological Term Annotations	1.0	null
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63086
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.64216
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094675
BRD-K03344897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67435
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08859
BRD-K65441343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86603
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13552
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CNOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06211
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85115
TBRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5025
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28399
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.21546
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921613
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11158
LAMA-84	GDSC Cell Line Gene Expression Profiles	1.0	2.19379
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1468
Gap junction trafficking and regulation	Reactome Pathways 2014	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2182
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11221
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72318
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
Gap junction trafficking and regulation	Reactome Pathways 2024	1.0	null
BRD-K00423214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29792
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27674
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10545
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-11A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interleukin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.345692
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
17023518-Table1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K03884263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07506
invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.571219
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12693
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83869
Gap junction trafficking	Reactome Pathways 2014	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07223
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02008
BRD-K25176380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15554
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24711
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3403
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	170.038
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.39816
17638894-Table2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08779
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
Pachyonychia congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Perturb_11743_KD_Nsd2_SRP312884	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.4172
Salivary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
hearing loss, noise-induced	GAD Gene-Disease Associations	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.425139
gap junction channel activity	GO Molecular Function Annotations 2025	1.0	null
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44809
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	2.24003
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03905
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gap junction assembly	Reactome Pathways 2024	1.0	null
BRD-K57167256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08205
GSE153189_1_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A75087829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28135
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.71501
BRD-K51600962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29158
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.435
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24555
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
GTEX-XV7Q-1126-SM-4BRVS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974326
macule	HPO Gene-Disease Associations	1.0	null
BRD-K09523238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01262
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053776
Keratoderma, Palmoplantar	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851895
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.341
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81547
BRD-K43820045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08235
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
flufenamic acid	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
cell communication	GO Biological Process Annotations 2015	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13948
Perturb_5606_KD_METTL1_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN012_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06847
Weight Loss	CTD Gene-Disease Associations	1.0	1.03084
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94584
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38881
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25812
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01685
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34482448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0383
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.204
keratosis	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
conjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.28294
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25658
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80273
abnormality of digit	HPO Gene-Disease Associations	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55812
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.936
Stereocilia tip link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14957
hsa-miR-4284	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
Noonan syndrome with multiple lentigines 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14153
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940258
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7747
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0071
LN443	DepMap CRISPR Gene Dependency	1.0	2.46785
BRD-K39087188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31911
BTK_KO_GDS1346_302_mouse_splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98406
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9597
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	0.902536
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055526
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12374
DG-75	GDSC Cell Line Gene Expression Profiles	1.0	1.54525
Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glaucoma	HPO Gene-Disease Associations	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044128
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.706
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rhombomere 8	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1794
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
infantile onset	HPO Gene-Disease Associations	1.0	null
CEDNIK syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26374
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K27229533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43368
BRD-K84062787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08395
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24164
Gap junction protein, cysteine-rich domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20018
polymerization	GeneRIF Biological Term Annotations	1.0	null
insights	GeneRIF Biological Term Annotations	1.0	null
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.443
GSE186767_1_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829871
MXRA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72865
Abnormality Of Cardiovascular System Morphology	DisGeNET Gene-Disease Associations	1.0	null
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26684
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.17809
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54146
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058872
BRD-K96758498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31179
Keratoderma	DisGeNET Gene-Disease Associations	1.0	null
Generalized Hirsutism	DisGeNET Gene-Phenotype Associations	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13798
weight loss	HPO Gene-Disease Associations	1.0	null
BRD-K45969405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57853
BRD-K50830147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27408
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28337
E2F6	ENCODE Transcription Factor Targets	1.0	null
palmoplantar keratosis	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5923
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.504973
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41357
ATP2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5378
envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.09526
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85292767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06565
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7851
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05256
BRD-K37831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72886
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15213
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876153
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.53005
ChIP_NACC1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35821
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26072
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44114
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050962
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53646
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.529
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A31602150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32534
BRD-K09149805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65171
bladder	GTEx Tissue Gene Expression Profiles	1.0	0.870354
layer 6 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11332
impaired olfaction	MPO Gene-Phenotype Associations	1.0	null
hydrometra	MGI Mouse Phenotype Associations 2023	1.0	null
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.935186
BRD-K35171408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42076
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38002
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21997380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19565
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3561
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neoplasm	HPO Gene-Disease Associations	1.0	null
CLPP_KO_GSE40207_392_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99742
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33341
Autosomal recessive nonsyndromic deafness 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.652
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50457
NACC1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04836
HuO-3N1	GDSC Cell Line Gene Expression Profiles	1.0	1.61593
malformation of the heart and great vessels	HPO Gene-Disease Associations	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82134
NFE2L2_KO_GDS514_699_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K00300115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37305
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62872
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.285
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.004
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46465
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43888
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25602
BRD-K05246869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2949
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9137
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9733
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8149
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23617
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40065
Hypertrichosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K90882192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30959
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43447
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96425
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01379
clouston syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.51765
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37822
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60802
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837756
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09217
BRD-K07981644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03273
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1835
RERFLCAD2	CCLE Cell Line Gene Expression Profiles	1.0	1.5477
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60389
CRCGN015_MCF10A_48H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3208
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835587
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09003
BRD-K82827604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63213
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.8533
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
diagnosed	GeneRIF Biological Term Annotations	1.0	null
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83862
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.72678
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05291
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28736
Eye-conjunctival epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	7.49705
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.85368
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.832329
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986194
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VM-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98496939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26425
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Lung adenocarcinoma_LUAD_TCGA-05-4433-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79365
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
connexin complex	GO Cellular Component Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
496100544_PCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01011
BRD-K74688087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1313
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	2.33695
BRD-K05248348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14165
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3511
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A5QV-01A-22R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.8798
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.37458
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-2.53812
keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.475223
L363	DepMap CRISPR Gene Dependency	1.0	2.96916
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58748
BRD-K96737756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65616
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30763
CRCGN014_HEPG2_3H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0302
BRD-K33710385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08922
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.51842
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5572
GPR137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9252
BRD-K09583061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27345
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23800773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18442
variants	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864294
hsa-miR-3665	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0658
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088468
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72031
LXF-289	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45864
single-organism behavior	GO Biological Process Annotations 2015	1.0	null
GSE174383_1_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52285987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09334
eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245491
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7493
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Agranular insular area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13342
TCCSUP	DepMap CRISPR Gene Dependency	1.0	2.35478
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:I21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.312
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40842
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24348
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.398
BRD-K86102179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17405
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78711
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.903522
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12246
hsa-miR-4464	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831985
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08538
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.66345
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr1_34794360_A_G_b38	GTEx eQTL 2025	1.0	1.05525
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
bidirectional	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60581
BRD-K34258763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27015
Autosomal recessive nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26448
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76408
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069226
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41448
BRD-A22502911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15946
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.375
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945727
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906685
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21889
Perturb_9005_KD_GATA6_SRP014027	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.1079
costa	GeneRIF Biological Term Annotations	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.20432
Anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.375
TP63_01_201	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59358
Perturb_6658_KO_Egfr_SRP188688	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.37004
BRD-A76899420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4892
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51031
Craniometaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875881
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K15654812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41897
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13568
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37001
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36153
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19146
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948736
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substitution	GeneRIF Biological Term Annotations	1.0	null
Corneal Opacity	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84956
ID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91639
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36875
GSE178714_6_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02113
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.922
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47588
BRD-K32403186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3172
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.646911
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.93592
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10433727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03192
143B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16935
keratoconjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.267977
BRD-K01077691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2286
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1914	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10963
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33347
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
keratosis follicularis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.70233
TPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21026
frameshift	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.752
SUIT-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.296
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42787
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93414
Lung squamous cell carcinoma_LUSC_TCGA-34-8455-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41955
Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03663
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Granulosa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
NUDT17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6917
Bullous congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873997
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06045
BRD-A17120244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21213
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8864
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HU-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Erythrokeratodermia variabilis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.824937
gap junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
Hyperkeratosis	DisGeNET Gene-Disease Associations	1.0	null
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
Charcot-Marie-Tooth disease X-linked dominant 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.589
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074645
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309335
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95001
body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.197369
Keratosis follicularis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
BRD-K04834648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0826
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
Hypermelanotic Macule	DisGeNET Gene-Phenotype Associations	1.0	null
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97114
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.923
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.095186
gynoecium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286026
BRD-K08311368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16432
BRD-K34277236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38225
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58893
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070145
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cx303	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.27492
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-T_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5112
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9788
Perturb_11864_KO|KD|OE_Trp53/Rb1|Kmt2c|Myc_SRP292755	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_16593_KO_Egfr_SRP188688	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.35928
GSE210667_1_v_0_rfx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K06480376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41916
BRD-K15008902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19809
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.49921
BRD-K52956006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05529
BRD-K24538875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15974
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13451
Connexin	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8075
Nucleolus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4357
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29588
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.36005
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.102924
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC35B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34995
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57249
KYSE180	CCLE Cell Line Gene Expression Profiles	1.0	1.4293
inflammatory abnormality of the skin	HPO Gene-Disease Associations	1.0	null
hsa-miR-3162-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58261
paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.24715
ParietalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.2993
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99924
YH13	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86954
BRD-K99214816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00227
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057789
opacification of the corneal stroma	HPO Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04233
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K75900952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.328
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44685
there	GeneRIF Biological Term Annotations	1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980065
abnormal spleen morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Z-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42671261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05988
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V0A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52663
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77246
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901622
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64098
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89846
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.07895
KKU100	DepMap CRISPR Gene Dependency	1.0	4.32502
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.87333
erythrokeratodermia variabilis with erythema gyratum repens	OMIM Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15444511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05425
BRD-K11662217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35421
hsa-miR-661	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46852
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.274
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16644
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956079
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCLFPEDS0008T	DepMap CRISPR Gene Dependency	1.0	2.16855
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
INS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36339
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48020855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31968
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33122655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34175
GJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7735
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49638
RL	DepMap CRISPR Gene Dependency	1.0	3.58413
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48481
TTC549	DepMap CRISPR Gene Dependency	1.0	3.05706
vascular skin abnormality	HPO Gene-Disease Associations	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15713
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23029
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7862-01A-21R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4653-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04437
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1246
Nonepidermolytic palmoplantar keratoderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76361
BRD-K93698227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49082
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24884
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oxprenolol-6145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
entropion	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05597
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50073
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040445
PMC9391581-mmc5.xlsx-WT_KLF4_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34942615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01264
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40155
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51496
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16896
BICR6	CCLE Cell Line Gene Expression Profiles	1.0	2.33425
BRD-K24502602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11238
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.902305
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MSTO211H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41076
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	2.69408
Lung adenocarcinoma_LUAD_TCGA-55-8089-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12347309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10987
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42476
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TP53I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10307
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09319
g12d	GeneRIF Biological Term Annotations	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1133
remains	GeneRIF Biological Term Annotations	1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09577
CLPP_KO_GSE40207_378_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63409
NCIH1395	CCLE Cell Line Gene Expression Profiles	1.0	1.56203
BRD-K74677971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11205
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.086745
SNU899	CCLE Cell Line Gene Expression Profiles	1.0	1.86284
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51851
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JURLMK1	CCLE Cell Line Gene CNV Profiles	1.0	2.06478
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
GSE169590_0_v_5_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.47849
BRD-K97276563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88112
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
revealed	GeneRIF Biological Term Annotations	1.0	null
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06983
PANC0403	CCLE Cell Line Gene Expression Profiles	1.0	1.8046
MOG-G-CCM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99785
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.07698
hsa-miR-3126-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.9572
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2707-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9391581-mmc4.xlsx-WT_KLF4_vs_GFP-activated-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79193
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055404
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53876
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842652
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065105
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8336
KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38843
BRD-K61726189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02347
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
mantle zone of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1257
ROCK_INHIBITION_GDS3944_463_mouse_Forebrain astrocytes - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2942
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4686
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896847
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56139
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2661
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21937
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861222
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66764
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72624
Hypotensive episode_Renal Tissue_GSE2401	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.57821
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02008
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862484
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79906
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
Stratum germinativum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15069
stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.732265
NCIH1836	DepMap CRISPR Gene Dependency	1.0	3.05627
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2827
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4668-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.929516
BRD-K53889798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13126
Erythrokeratodermia, Progressive Symmetric	CTD Gene-Disease Associations	1.0	2.88009
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27612721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11203
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055985
families	GeneRIF Biological Term Annotations	1.0	null
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.126797
BRD-K23533429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02798
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83121
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.507
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29797
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16897
mantle zone of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13054
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984902
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938428
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68229
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.42641
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K19411393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40848
Erythema	DisGeNET Gene-Phenotype Associations	1.0	null
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86008
BRD-K08262651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12802
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36417
Perturb_18393_KO_923large_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.70902
BRD-K71533707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40046
NR1I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75007
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04088
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CARMIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51432
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88156935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01494
Abnormalities, Multiple	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25094
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7099
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09319
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.26495
GAL3ST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08425
Agranular insular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02322
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47275
MEDNIK syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
JVE127	DepMap CRISPR Gene Dependency	1.0	2.06646
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18078
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67F-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68422
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267102
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7430-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95323025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16709
H3K36me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468048
epidermal	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0303
Perturb_17293_KD_lncRNA5251_SRP239062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99741
H3K36me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846995
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15749
CEBPB_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Charcot-Marie-Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71629
growth delay	HPO Gene-Disease Associations	1.0	null
Human - Tonsil - L2 - Crypt	HuBMAP Azimuth Cell Type Annotations	1.0	null
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05322
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56076
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68098
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_40_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Mutilating palmoplantar keratoderma with periorificial keratotic plaques	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
Juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
flunisolide-4303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5978
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829871
hearing	GeneRIF Biological Term Annotations	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30323
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.39473
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-1226-SM-4BRUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825346
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03043
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871633
BRD-K32084247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26541
BRD-K08903301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36144
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal recessive nonsyndromic deafness 24	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0217
hsa-miR-320c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PRDM14	ChEA Transcription Factor Targets	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
bhlha15_17170023_pancreas_lof_mouse_gpl339_gds1731	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.50108
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alopecia	HPO Gene-Disease Associations	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9437
phenotypes	GeneRIF Biological Term Annotations	1.0	null
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05195
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Vesicle-mediated transport	Reactome Pathways 2024	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-AsPC1_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01026
Hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
Columnar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04065
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3059
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.652183
hsa-miR-3622a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SGC-7901 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5254
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08024
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09098
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10918
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.458
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45546
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62047
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895949
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75533
NCIH854	CCLE Cell Line Gene Expression Profiles	1.0	1.41356
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34
PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.434148
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44147
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K87193132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2138
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830677
Perturb_14556_KO_KLF5_SRP051606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.3566
all	HPO Gene-Disease Associations	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K06218527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05327
BRD-K93459372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15749
BRD-K15794956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57835
BRD-K10459843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06669
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
Atherosclerosis_Hepatic Tissue_GSE363	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.31726
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A62469171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59968
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.33056
CRCGN014_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11598
preweaning lethality, incomplete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66186
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Diazinon	CTD Gene-Chemical Interactions	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2016
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48505
BRD-K90702609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37397
CORL24	CCLE Cell Line Gene CNV Profiles	1.0	2.59944
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
nucleolus	GO Cellular Component Annotations 2023	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052374
HCC1143	CCLE Cell Line Gene Expression Profiles	-1.0	-2.66992
EPLC272H	CCLE Cell Line Gene Expression Profiles	1.0	1.89769
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8034
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422673
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05435
Autosomal recessive congenital ichthyosis 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.838
Morris hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8888
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302838
hsa-miR-3921	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.99992
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911299
A_CA_04_2009_4dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.82508
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QR-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG-19884340-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K16641781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13394
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051577
GSE176008_0_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118077_1_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15742845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3364
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13458
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16278
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945984
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91148820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18656
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K67817697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49973
BRD-K09468701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85494
provide	GeneRIF Biological Term Annotations	1.0	null
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.595656
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K97263385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30298
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33678
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92773
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A780-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4527	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type 2 diabetes mellitus_Pancreas_GSE2470	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.991452
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943667
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041854
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66574
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.839071
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936118
HSF1_KD_GDS1733_753_human_HeLa cells - 4 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
common	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.85098
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1327
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
gap junction channel activity	GO Molecular Function Annotations 2023	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LV-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
BRD-K35122752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3259
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9414
BRD-K77634326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49509
BRD-K31851055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09724
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11708
BRD-K87920761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72795
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93469
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Punctate palmoplantar keratoderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.52517
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.5963
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.50335
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.259473
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87483
Hyaline layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31252
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24348
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Melanophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21673
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42105
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.59993
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3239
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
hsa-miR-548al	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85371
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-637	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
into	GeneRIF Biological Term Annotations	1.0	null
abnormality of the nail	HPO Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54328
CRCGN014_HEPG2_3H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17838
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056532
Lung adenocarcinoma_LUAD_TCGA-55-6984-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
decamethonium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10142
PMC10794847-mmc6.xlsx-PIAS1_KD_up-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.1694
hsa-miR-4252	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.415
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4236
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.42354
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04296
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.353
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3636
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69532
PMC10205041-Table1.doc-0-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9424
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K60948317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29555
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HUNK_knockout_240_GSE14226	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.29139
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29245
S117	CCLE Cell Line Gene Expression Profiles	1.0	2.86943
BRD-K87258738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01592
CFPAC1	CCLE Cell Line Gene Expression Profiles	1.0	2.49397
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2903
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3663
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03043
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.50114
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2222
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33915
erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	3.2569
BRD-K32418104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0973
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36064
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4432
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55835264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33422
BRD-K40300525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37521
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
generalized abnormality of skin	HPO Gene-Disease Associations	1.0	null
BRD-K24727463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20243
Autosomal dominant nonsyndromic deafness 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
Anchoring junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39907
modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.577215
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3616-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.837
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88408
Palmoplantar keratoderma and congenital alopecia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.605
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6706
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898767
HERPUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30907
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_18394_KO_Ivl_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.9276
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93284
BRD-K12578029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08203
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065465
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057787
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50147
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03816
neoplasm by anatomical site	HPO Gene-Disease Associations	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9646
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826058
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCTANOL	DGIdb Drug Targets 2026	1.0	0.630143
BRD-K28039328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24635
kidney failure, chronic	GAD Gene-Disease Associations	1.0	null
X-linked chondrodysplasia punctata 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
Necrosis	CTD Gene-Disease Associations	1.0	1.24275
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12418
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1661
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13693
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80724
MAVER1	DepMap CRISPR Gene Dependency	1.0	3.35929
Gap junction trafficking	Reactome Pathways 2024	1.0	null
ASPC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K28429328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32955
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07613
single-organism process	GO Biological Process Annotations 2015	1.0	null
BRD-K04468899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49898
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8524
nabumetone-6327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08497
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55219
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
taste/olfaction phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1	ENCODE Transcription Factor Targets	1.0	null
nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08034
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_WT_KLF4-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04497
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15354
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1476
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08094
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
abnormal spleen morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35062
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26943
Agranular insular area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00685
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24058
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_64_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K11610091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27181
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55037
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22355
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22405
PANC1005	DepMap CRISPR Gene Dependency	1.0	3.91428
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5758
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K25203350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21962
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09189
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95467
BRD-K45723655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71963
connexon complex	GO Cellular Component Annotations 2015	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24348
Neural crest cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4309
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39601
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44696
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29138092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07928
abnormality of the pinna	HPO Gene-Disease Associations	1.0	null
Osteoclastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
cumulus-oocyte complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41645
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832806
PMC11551338-pnas.2411189121.sd01.xlsx-VDR-Unnamed_0_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53909
Skin Diseases, Genetic	HuGE Navigator Gene-Phenotype Associations	1.0	null
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13284
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29851
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44559
BRD-A77164655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02449
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963697
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9322
stratum germinativum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.31784
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829871
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31803
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940546
Gap junction beta-5 protein (Cx30.3)	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6632
BRD-K60337438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07175
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7987
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12911
mRNA_ESRRB_19136965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_16432_OE_E2f4_SRP327850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.48701
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58996
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47275
496100492_TCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58145
BRD-K10412976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11538
FLUFENAMIC ACID	DGIdb Drug Targets 2026	1.0	0.348237
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04082
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.06416
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3483
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 5 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03262
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41985
BRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55349
NR0B1	ChEA Transcription Factor Targets	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DYNC2I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05314
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Rce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
LMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7774
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	1.8347
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81435
Hypohidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5929
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052793
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36993
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972999
Linear skin defects with multiple congenital anomalies 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
BRD-K34703146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78361
Erythrasma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07704
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16158
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2758
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.323365
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45264
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
x-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.691094
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.76921
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.872327
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31779
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
etiology	GeneRIF Biological Term Annotations	1.0	null
BRD-A57285050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63342
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.848378
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0485
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869598
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0763
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00702
BRD-K99220724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65088
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
SNU1076	CCLE Cell Line Gene Expression Profiles	1.0	2.35366
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96946
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04648
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.61233
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6273
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43476
related	GeneRIF Biological Term Annotations	1.0	null
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28028
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Adrenocortical carcinoma_ACC_TCGA-OR-A5L8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BE2M17	DepMap CRISPR Gene Dependency	1.0	5.26124
CARBENOXOLONE	DGIdb Drug Targets 2026	1.0	0.508961
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-NFKB1-HIT_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
TCF3-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83065
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Exposure keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
METTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96023
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-0626-SM-4DM5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872553
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
phenotype	GeneRIF Biological Term Annotations	1.0	null
BRD-K58762810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36944
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06352
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.002
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35758
BRD-K79303560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79525
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19773
BRD-K07164317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62965
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901622
GSE135352_6_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47304
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40029
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.86684
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22959
Epidermal nevus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.875
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18654
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.885569
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
647-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64682
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6849
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.24388
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34298
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
Perturb_1290_KO_Lef1_SRP111197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.75659
erythrokeratoderma	GeneRIF Biological Term Annotations	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840738
19036130-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
RDES	DepMap CRISPR Gene Dependency	1.0	3.33123
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48001
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.48384
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00168
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39655
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04278
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.40985
ZNF646	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78416
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
496100565_FWM_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02204
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.652435
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRF	MotifMap Predicted Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSUN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60662
Prostate adenocarcinoma_PRAD_TCGA-HI-7170-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC251	DepMap CRISPR Gene Dependency	1.0	7.3801
gallbladder	HPA Tissue Gene Expression Profiles	1.0	0.946856
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.942424
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.545
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dry Skin	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95741
NCIH82	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64533
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058894
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
Submucosal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96731
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57236
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11311
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39992
GSE239898,GSE239899_1_v_0_hiltonol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99589
BRD-K23585987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39786
Triglyceride levels x thiazide or thiazide-like diuretics use interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
SOX2	ChEA Transcription Factor Targets	1.0	null
gjb4	GeneRIF Biological Term Annotations	1.0	null
HNF4alpha_KO_GDS1915_173_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09711
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	1.51233
LRRC10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37977
BRD-K58971526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28333
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0632
MAPK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65099
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23698
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Strabismic amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
cataract	HPO Gene-Disease Associations	1.0	null
Junctional zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
BRD-K02548315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11203
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62177
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111102,GSE111105_8_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45928581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25039
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39068
Perturb_16480_KO_Ring1a/Ring1b_SRP136563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.06746
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.667622
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65109
BRD-K42271016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05607
TM6SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.12192
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory behavior	GO Biological Process Annotations 2015	1.0	null
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81716
BRD-K06398048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05948
CLPP_KO_GDS4791_104_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CLPP_KO_GDS4791_537_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K56616847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26406
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCCIT	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.206423
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K91084609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30323
explanation	GeneRIF Biological Term Annotations	1.0	null
BRD-K88385836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38342
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92574
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Spastic quadriplegic cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67365
Autosomal recessive congenital ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
Sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46595
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.666358
abnormality of the testis	HPO Gene-Disease Associations	1.0	null
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13872
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923388
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-1280	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07245
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.736
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06048
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.73977
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878716
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.453
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.56361
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11573
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62122
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86141
long fingers	HPO Gene-Disease Associations	1.0	null
BRD-K74363294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23166
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.567997
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54545
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Classical_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.263
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K26161397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0229
BRD-K74873856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06127
DGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49233
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15747
BRD-A93436351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7469
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.184241
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22464
conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.304279
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02024
BRD-K54456668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47969
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040874
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K03305572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02415
BRD-K30301272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18823
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59658
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.9258
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.35692
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15991
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45606
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40767
BRD-K73581966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26059
M14	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43112
BRD-K28698418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13445
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2256
BRD-K85546819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77263
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63449
Pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX11_DEPLETION_GDS4801_326_human_Z138 mantle cell lymphoma (MCL) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Autosomal recessive craniometaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
496100279_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01151
KDM5B	ENCODE Transcription Factor Targets	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984902
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50576
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17411
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53466
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36357
cellular_component	GO Cellular Component Annotations 2015	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.42084
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.99635
BRD-K75869095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12921
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19509
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REEP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96021
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30472
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4114
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65048
GSE211931_1_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97122937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14419
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93395
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6995-01A-31R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive nonsyndromic deafness 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
carpel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287803
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19K-01A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-320a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84765
Perturb_8749_OE_TP53_SRP131095	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Autosomal dominant mutilating palmoplantar keratoderma with periorificial keratotic plaques	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.266
Syndactyly type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
Ebolavirus(EBOV)_6day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.3469
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.956
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7415-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal uterus morphology	IMPC Knockout Mouse Phenotypes	1.0	null
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94316
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71063
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.184241
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73127
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-61603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59261
MERO48A	DepMap CRISPR Gene Dependency	1.0	3.00738
HSC3	CCLE Cell Line Gene Expression Profiles	1.0	1.36824
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.325
Perturb_8415_KO_Cd302_SRP230435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.23851
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042004
Stereocilia coupling link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
Hearing Loss, Noise-Induced	HuGE Navigator Gene-Phenotype Associations	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898767
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69603
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51868
Pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904365
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
Hand Deformities, Congenital	HuGE Navigator Gene-Phenotype Associations	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07704
BRD-K60052521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51811
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26331
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.689
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8350-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.82544
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MM-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70996
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51591
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37288
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97098
Pendred Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
639V	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51681
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78013
region	GeneRIF Biological Term Annotations	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25809
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18829
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60163
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65462
CAL-27	GDSC Cell Line Gene Expression Profiles	1.0	1.42601
HSF1-23293686-STHDH_STRIATAL-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5754
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
connexon complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Connexin, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
irregular hyperpigmentation	HPO Gene-Disease Associations	1.0	null
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13849
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.46184
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.77774
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91672
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72358
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20969
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13458
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.739266
H3K36me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207787_1_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
connexin	GeneRIF Biological Term Annotations	1.0	null
Ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51024
BRD-K96353852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28402
HMCES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89816
Neurological pain disorder_Dorsal Root Ganglia_GSE15041	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.02397
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956626
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15568
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11406
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_7_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62264
five	GeneRIF Biological Term Annotations	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0841
KLF4	ChEA Transcription Factor Targets	1.0	null
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05555
clinically	GeneRIF Biological Term Annotations	1.0	null
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.95683
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.986294
Perturb_4556_KD_Ncor2_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50568
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NACC1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7726-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142630_0_v_2_hiltonol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.968415
BRD-K73942403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04196
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31577
BRD-K34018387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38151
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.385436
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24626
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65127
same	GeneRIF Biological Term Annotations	1.0	null
STAT3_OE_GDS3444_576_mouse_Cultured embryonic stem (ES) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839871
palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.29615
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01906
Gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
Hearing Loss	HuGE Navigator Gene-Phenotype Associations	1.0	null
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
Stratum basale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.594
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25448
nucleolus	GO Cellular Component Annotations 2025	1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1261
BRD-K95385525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29048
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87226
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01543
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78408
coding	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03283
Wart	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75387
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38487
FTC-133	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49558
hsa-miR-4435	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_6732_KO|KD_UPF3B|UPF1_SRP327782	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.60129
Alopecia	DisGeNET Gene-Disease Associations	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r8 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1257
POLR2A	ENCODE Transcription Factor Targets	1.0	null
cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.303655
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92703
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
Lamellar body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.515
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72468
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00107
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46757
Lung squamous cell carcinoma_LUSC_TCGA-18-3412-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25555
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69929
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4512
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41784
KO52	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_14703_KO_Trp53|Kras_ERP118222	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.42696
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52564
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35854
Membrane Trafficking	Reactome Pathways 2014	1.0	null
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09319
BRD-K97721960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37053
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93637
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K32370845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77561
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82722
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7465
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6849
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97396
USF1	ENCODE Transcription Factor Targets	1.0	null
Abnormal Blistering Of The Skin	DisGeNET Gene-Phenotype Associations	1.0	null
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.739678
BRD-K45612428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74985
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37729
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32652
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4756-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K59392325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37326
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06517
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4668-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.401
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11221
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92073
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.561
diseaseassociated	GeneRIF Biological Term Annotations	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.830689
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-3153	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
Cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE218814_1_v_0_suv39h1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3078
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03283
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24492
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01906
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325335
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1260b	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
BRD-K48501991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00531
tiratricol-1412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81522184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09621
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0967
IHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060074
BRD-K07460436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79286
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RR-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-XQ8I-1526-SM-4BOOH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919287
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32828
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUU-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46155894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6428
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34495
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01692
epidermal thickening	HPO Gene-Disease Associations	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98648
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFE184	CCLE Cell Line Gene Expression Profiles	1.0	1.96203
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.031
palmoplantar keratoderma	HPO Gene-Disease Associations	1.0	null
BRD-K21253219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1482
496100610_TCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15108
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.888185
hyperpigmentation of the skin	HPO Gene-Disease Associations	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11123
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Helaohio	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97406
BRD-K77820762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04185
Tapering Fingers (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
DNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93324
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.879405
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79493
mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366007
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23561
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.629635
H3K36me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43888
C17orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81959
95T1000	DepMap CRISPR Gene Dependency	1.0	2.89921
abnormality of cardiac morphology	HPO Gene-Disease Associations	1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58999
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
NACC1	ChEA Transcription Factor Targets	1.0	null
EOL-1-CELL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
BRD-K79735667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01332
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829871
NZOV9	DepMap CRISPR Gene Dependency	1.0	2.12219
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2518
HTR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52638
letter	GeneRIF Biological Term Annotations	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Insulinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.2062
Naxos disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
patchy palmoplantar keratoderma	HPO Gene-Disease Associations	1.0	null
BRD-K77950699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21853
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62545
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8453
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047895
SW156	DepMap CRISPR Gene Dependency	1.0	4.40123
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00647
BRD-K05799189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15927
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K33775409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28714
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057818
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
BRD-K24133768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26133
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.6279
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
Hypomyelinating leukodystrophy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64142
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.559
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07812
TSFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29092
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33563
LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
t-lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281423
ITGA7_OE_GDS3209_142_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K40318276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08521
sensory perception	GO Biological Process Annotations 2015	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	2.56071
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLX5_Deficiency_GDS4443_356_mouse_E10.5 embryos otic vesicle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0864
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44685
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57226
BRD-K14813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05476
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56979
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28345
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96731
diabetes mellitus	HPO Gene-Disease Associations	1.0	null
BRD-K06181307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23887
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K13090434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32555
MOV10L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36432
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_69_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI H226	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14678
Gap junction assembly	Reactome Pathways 2014	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6304
BRD-K51461946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0758
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.71105
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
Photosensitivity Of Skin	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7441
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01854
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.616312
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2243
WB-4101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48235
BRD-K44042747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0471
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65653
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.75115
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37529
GSE158632_2_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03823
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K87743988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26889
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67902
BRD-K69152679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19005
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871511
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K49050984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29906
EWS502	DepMap CRISPR Gene Dependency	1.0	3.03086
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23064726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15162
nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489838
BRD-K14875480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37114
496100331_TCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13725
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52813
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41998
TCF3	ChEA Transcription Factor Targets	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066157
growth abnormality	HPO Gene-Disease Associations	1.0	null
Agranular insular area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1219
Dry Skin, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
U-698-M	GDSC Cell Line Gene Expression Profiles	1.0	1.73554
CAL120	DepMap CRISPR Gene Dependency	1.0	2.50846
CEBPB_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03816
GSE201735_3_v_1_cdca7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34669
Brain Lower Grade Glioma_LGG_TCGA-HT-8105-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Weight Decreased	DisGeNET Gene-Phenotype Associations	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4161
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20362
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23323
TO14	DepMap CRISPR Gene Dependency	1.0	4.1043
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44116
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36953
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03976
f1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11906
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832544
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WW-01A-22R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85441584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46575
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55731
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13478
ekv	GeneRIF Biological Term Annotations	1.0	null
liminal part of the r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13054
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
AR	ChEA Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.61348
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5948
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
BRD-K00611112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98178
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sweat gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
Ainhum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.31
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6403
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.781869
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09375
Hearing Loss, Sensorineural	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K98109987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30939
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22711
juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052725
clinical modifier	HPO Gene-Disease Associations	1.0	null
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.65426
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46999
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13853
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05918
corneal opacity	HPO Gene-Disease Associations	1.0	null
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17838
BRD-K93677460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19635
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57801
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
synthesis	GeneRIF Biological Term Annotations	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1200	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
thickened skin	HPO Gene-Disease Associations	1.0	null
OVCAR8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46099
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52601
Osteogenesis imperfecta type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
496100344_HIP_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30816
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3027
BRD-K00086692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45412
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04234
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89785
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.968
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17262
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1	ChEA Transcription Factor Targets	1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66738
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63402
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1405
gap junction	GO Cellular Component Annotations 2023	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9669
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19907
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07736
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51324
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79642
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3661	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056828
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64479
IGFBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82788
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5511
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069682
A172	BioGPS Cell Line Gene Expression Profiles	1.0	1.02142
sequencing	GeneRIF Biological Term Annotations	1.0	null
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11774
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11976
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thymus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121744
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077693
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
Nail Abnormality	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K78196882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34021
fisetin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17937
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28963
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.414
chr1_34756713_T_TTGGTCATGCTTCAAA_b38	GTEx eQTL 2025	1.0	2.4998
BRD-K25081075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06046
E2F1	ChEA Transcription Factor Targets	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of the cornea	HPO Gene-Disease Associations	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34184
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05251
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054664
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.79631
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63493
GTEX-QCQG-1226-SM-48U23	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859056
BRD-K50685439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37777
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THP1	DepMap CRISPR Gene Dependency	1.0	2.04647
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1888
Perturb_13325_KD_Klf8_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.5736
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24006
GSE89018_10_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42945
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24474
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18551
BRD-K71563254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24898
X-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84766
TRPV4_DEPLETION_GDS4851_89_mouse_3T3-F442A adipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13458
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43618
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24127
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
BRD-K08806664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32404
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
symmetric	GeneRIF Biological Term Annotations	1.0	null
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85435
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9029
GSE193993_0_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931125
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3814
ZNF501	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56112
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51301
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01968
Perturb_174_KD_Asns_SRP119931	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K28391526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19056
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852696
tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073724
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056815
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24833
cell communication	KEGG Pathways	1.0	null
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06666
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933597
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51333
abnormality of the endocrine system	HPO Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15481
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27273
Eb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02136
RARG-19884340-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50857
FOXP1	ChEA Transcription Factor Targets	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064047
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28996
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEMA6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46393
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36417
Pityriasis rubra pilaris	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAPKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37815
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09615
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922779
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A678-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19546
Membrane Trafficking	Reactome Pathways 2024	1.0	null
dentin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307528
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59985
Calcium Regulation in the Cardiac Cell(Mus musculus)	WikiPathways Pathways 2014	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6103
hsa-miR-1343	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.0205
BRD-K35156336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03402
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17918
Primary somatosensory area, nose, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2401
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864093
Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCCLMS1C1	DepMap CRISPR Gene Dependency	1.0	2.65066
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36354
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5607_KD|OE_METTL1|RPTOR_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18866
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33644
Perturb_13103_KO_Immt_SRP404364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80778
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01449
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Agranular insular area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0729
BRD-K86584551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83868
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2446
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06554
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83858
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00962
abnormal olfactory system physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K28512751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0547
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PEA1	DepMap CRISPR Gene Dependency	1.0	3.03569
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6095
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
Autosomal recessive congenital ichthyosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15024
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10827
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845872
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mevalolactone-2718	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20946
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59843356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04593
NANOG-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1328
TLX1::NFIC	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K29711480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00221
true	GeneRIF Biological Term Annotations	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71885
acid	GeneRIF Biological Term Annotations	1.0	null
mRNA_ETV3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08983
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07254
abnormality of skin pigmentation	HPO Gene-Disease Associations	1.0	null
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88657
BRD-K72060903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24566
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
BRD-K90797575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00528
PANC1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05531
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K90874005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5512
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52238
Cataract	DisGeNET Gene-Disease Associations	1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13995
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.976
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98443
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42443
PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MUTZ8	DepMap CRISPR Gene Dependency	1.0	10.3875
BRD-K24565713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.241
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.583
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51628
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56533
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81002
dry skin	HPO Gene-Disease Associations	1.0	null
el-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449886
COLO-741	GDSC Cell Line Gene Expression Profiles	-1.0	-2.1404
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4498179-srep11671-s1.pdf-131-IRF6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.577215
Perturb_16477_KO_Cyp26b1_SRP015254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.8398
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Lung adenocarcinoma_LUAD_TCGA-44-A4SS-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ichthyosis vulgaris	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85714
skin	HPA Tissue Gene Expression Profiles	1.0	1.705
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824563
HEK-293F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878716
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
integumentary system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Netherton syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.881
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.271
BRD-K42976515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10757
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6155
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.912
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4036
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982256
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DI-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92910000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19464
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2724-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
p107_Deficiency_GDS3176_606_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.258
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Erythrokeratodermia variabilis et progressiva	ClinVar Gene-Phenotype Associations 2025	1.0	null
chemosensory behavior	GO Biological Process Annotations 2015	1.0	null
Ectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.085
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63402
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4219
GSE201882,GSE201883_3_v_4_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
WTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56599
urinary bladder	HPA Tissue Gene Expression Profiles	1.0	0.950576
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5789
BRD-K57786075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11337
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076598
Autosomal recessive nonsyndromic deafness 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.679
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65802
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0985
variabilis	GeneRIF Biological Term Annotations	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92884
BRD-K28329571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25644
KRAS.DF.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10018
bart-pumphrey syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.47989
Perturb_13075_KO_Atm_SRP062722	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
aplasia/hypoplasia involving the central nervous system	HPO Gene-Disease Associations	1.0	null
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.19561
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19162
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90814
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
STC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46208
BRD-K76318449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28409
localized skin lesion	HPO Gene-Disease Associations	1.0	null
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-CESC_AND_UCEC_NOT_BRCA_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-3911-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal liver morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K08629159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49821
skin rash	HPO Gene-Disease Associations	1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cataract 14 multiple types	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Lung adenocarcinoma_LUAD_TCGA-05-5715-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01311
abnormality of carbohydrate metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04559718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31369
PMC7914369-thnov11p3676s2.xls-BPTF-signature-geneId_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3481
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_AsPC1-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94879
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051946
BRD-K37029442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25262
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91033
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35111
BRD-K53489056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55739
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54101
BRD-K78397696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57953
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46723
had	GeneRIF Biological Term Annotations	1.0	null
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.56937
hyperkeratosis	HPO Gene-Disease Associations	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.127996
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
GTEX-P4PP-2526-SM-3P61P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92082
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brachydactyly syndrome	HPO Gene-Disease Associations	1.0	null
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45461
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03187
TTC709	DepMap CRISPR Gene Dependency	1.0	3.68452
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5604_KD_METTL1_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
short stature	HPO Gene-Disease Associations	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96147
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.61915
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07132
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3588
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57061
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.75538
BRD-K84601599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26678
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19929
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26628
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K66700691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01663
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2886
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44833
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955172
KLE	CCLE Cell Line Gene CNV Profiles	1.0	1.43514
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL29	CCLE Cell Line Gene Expression Profiles	1.0	1.59793
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09511124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96698
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73516
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039529
BRD-K65913831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6771
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	5.05447
COPS7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43988
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal hair quantity	HPO Gene-Disease Associations	1.0	null
aplasia/hypoplasia of the cerebrum	HPO Gene-Disease Associations	1.0	null
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056677
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939359
Theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46171
BRD-K72745710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52265
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94989
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.27721
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central amygdalar nucleus, capsular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18513
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1763
BRD-K70093308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4594
HSF1	ChEA Transcription Factor Targets	1.0	null
allow	GeneRIF Biological Term Annotations	1.0	null
MHH-CALL-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4748	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8852
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055093
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878716
IGSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42617
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52068
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05481
MAX	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96731
BRD-K59626557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25771
HT-144	GDSC Cell Line Gene Expression Profiles	1.0	1.62286
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34026
Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50464
BRD-K12345912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11805
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	3.13407
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.97392
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978069
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46764
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080162
BRD-K77139764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61432
langerhans cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278955
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.893
Lung squamous cell carcinoma_LUSC_TCGA-21-1078-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-635	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8939
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976718
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17508
BRD-K03937692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01197
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.81879
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.131
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100192
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	2.09574
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	1.0	null
harbor	GeneRIF Biological Term Annotations	1.0	null
BRD-K97339945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11623
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35125
abnormality of skin morphology	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G401	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03053
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1506
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
JUN	ENCODE Transcription Factor Targets	1.0	null
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83096
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.28
GORASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91938
erythema	HPO Gene-Disease Associations	1.0	null
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.35375
TCF3-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H508	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43N-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APOBEC3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0602
PMC6802116-41467_2019_12517_MOESM5_ESM.xlsx-Sheet1-D9_8_GNF2-SERPINB5_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A53463743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43904
Lens epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
PMC4783780__F8	PFOCR Pathway Figure Associations 2024	1.0	null
DDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66356
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44685
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0331
connexin complex	GO Cellular Component Annotations 2025	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01906
BRD-K30025024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38901
BRD-K72713703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27714
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6397
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VP229	DepMap CRISPR Gene Dependency	1.0	2.18825
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81369
hsa-miR-320d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45121
BRD-K56415410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20606
OTUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20393
EP300	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.468
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal liver morphology	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97729
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01473
BRD-K81997160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0592
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3348
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.139964
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15588
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60666
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6474
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
Myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46339
hsa-miR-1225-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20742
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Ebl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.893
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.962
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49288
congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23777
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35367
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96115
causing	GeneRIF Biological Term Annotations	1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65149
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52584
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72455
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13688
CA2+	DGIdb Drug Targets 2026	1.0	0.322756
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17218
TP63	ChEA Transcription Factor Targets	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968417
BRD-K84077642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54232
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.979
laudanosine-1741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-764	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02899
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DC-01A-31R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1282
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36324810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07101
Perturb_6440_KD_Pten_SRP280101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K11741103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08613
BRD-K61432982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7036
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24112
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54187
papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.605762
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20628
HCC1187	DepMap CRISPR Gene Dependency	1.0	8.42287
BRD-K87277021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17932
BRD-K30551445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28085
Perturb_9150_KD_WTAP_SRP307037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.45199
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92712
HSF1-23293686-STHDH-STRIATAL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4307
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26374
BRD-K94489736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07501
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
BRD-K33420995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04952
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57651
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44258
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60289
T84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17104
BRD-K90004516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08688
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.64635
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07160586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63435
METTL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23139
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5326-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38487
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64832
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14795
hsa-miR-3144-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43535
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
abnormal uterus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66145
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14949
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73403
Erythrokeratoderma	DisGeNET Gene-Disease Associations	1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34148
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02713
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-175-VII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45579
BRD-K61213827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55818
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
BRD-K31666797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00967
BRD-K20906316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10512
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79484
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20093
Perturb_5742_KO_Id4_SRP260265	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.52451
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76478
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.564
BRD-K41603100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13779
Connexin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890067
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219707
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23234
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.7635
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17975
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12223973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72298
PWWP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62611
BRD-K04968881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39607
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
hsa-miR-4437	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
CHURC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65349
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24343
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.6925
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63815
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36667
Hereditary spastic paraplegia 44	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
BRD-K23204014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03545
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.11561
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04801
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6491-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10182289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57474
tapered finger	HPO Gene-Disease Associations	1.0	null
hsa-miR-1825	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC10988846-13073_2024_1323_MOESM4_ESM.xlsx-Methyl_Expr_AA_T_vs_NT-Additional_File_2_Correlation_between_methylation_and_expression_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08238
BRD-K56536691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22899
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A79097167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83095
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2215
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062008
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48081
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Erythrokeratodermia variabilis	ClinVar Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
involvement	GeneRIF Biological Term Annotations	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13919
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848102
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43455
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21345
BRD-K87073572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79752
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30651
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55461
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.930361
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78335
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05413
Inherited Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21017
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0477
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43446
BRD-K80073743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01622
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23061
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72004
ichthyosis vulgaris	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.755342
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71267
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.18906
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11343
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.164
JHU029	DepMap CRISPR Gene Dependency	1.0	2.20707
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49712
BRD-K29756429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58092
Early endosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.893
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	1.43055
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
BRD-A07214340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28653
GSE176305_0_v_1_rotenone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07618
TPCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99667
stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.665995
Hyperkeratosis, Epidermolytic	CTD Gene-Disease Associations	1.0	2.88009
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4837
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27402
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73822
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11332
hsa-miR-631	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K51196703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51458
SPRING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79308
Lung squamous cell carcinoma_LUSC_TCGA-39-5029-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26139
BRD-K93391478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6766
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.36648
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37203945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01236
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20393
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14253
CEBPB	ENCODE Transcription Factor Targets	1.0	null
MOLT4	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.992311
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypertrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20952
stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04664
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3171
Lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
BRD-K91998226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18185
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
YAPC	CCLE Cell Line Gene Expression Profiles	-1.0	-2.66224
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65765
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936823
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.54594
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15083
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nicotinic acid-3043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94459
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.843
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85051145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00007
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medulla, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09193
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3999
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48646
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40189164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36163
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.562
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49086
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.857
REST	ENCODE Transcription Factor Targets	1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53876
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0019
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061337
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52584
BRD-K89338336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42825
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	GDSC Cell Line Gene Expression Profiles	1.0	1.49661
BRD-K37658621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04299
Hmgn1_KO_GDS5010_406_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11092
wide pore channel activity	GO Molecular Function Annotations 2025	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
BRD-K19752998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2481
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829903
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21773
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
neutral lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.903621
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Ehlers-Danlos syndrome musculocontractural type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901622
H2AC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12369
skin	GTEx Tissue Gene Expression Profiles	1.0	2.119
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.476
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
786-0	GDSC Cell Line Gene Expression Profiles	1.0	1.51485
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1867
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4189
VASH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81614
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64688
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20842
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2552
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01911
TM7SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76279
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96731
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88456
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Nonsyndromic Deafness	DisGeNET Gene-Disease Associations	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4716
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21695
BRD-K18094884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09115
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05009
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K05753543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09032
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6041
Perturb_5506_KO_Nir_SRP114858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Dendritic shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55736
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
ERV3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34765
CLPP_KO_GDS4791_107_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.37002
BRD-K83895653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32299
QGP1	CCLE Cell Line Gene CNV Profiles	1.0	1.40421
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.888397
ATF3-27146783-CHIP-SEQ-COLON-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE48812_3_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01178
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.896
Perturb_13068_KO_Ssrp1_SRP338348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.35808
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4U-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K59045095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37206
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32807
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
individuals	GeneRIF Biological Term Annotations	1.0	null
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12427
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84206
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS1718	DepMap CRISPR Gene Dependency	1.0	3.3839
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11708
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86767
Erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.687
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of finger	HPO Gene-Disease Associations	1.0	null
Connexin complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
other	GeneRIF Biological Term Annotations	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
UHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28941
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02182
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24782
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
Gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
hearing abnormality	HPO Gene-Disease Associations	1.0	null
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7115
hypertrichosis	HPO Gene-Disease Associations	1.0	null
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
progressive	GeneRIF Biological Term Annotations	1.0	null
RI1	DepMap CRISPR Gene Dependency	1.0	5.72193
BRD-K25236390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51062
BRD-K93396907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09159
RLIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98686
Palmoplantar keratosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
enlarged uterus	IMPC Knockout Mouse Phenotypes	1.0	null
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A13983189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78517
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8713
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.59698
BRD-K67931592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02261
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27058
Perturb_13184_Mut_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.83776
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.541
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
a15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
BRD-K42511168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87897
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47677
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.68384
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825534
IDH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12572
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84352
harpagoside-6636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC2A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95496
hsa-miR-492	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.81878
HS-294T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
Lung adenocarcinoma_LUAD_TCGA-69-8453-01A-12R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7647
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20674
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Keratohyalin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853797
hsa-miR-4776-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167688
keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.184128
18722011-SuppTable2k	GeneSigDB Published Gene Signatures	1.0	null
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14957
ROGDI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28944
Hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68582
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35084
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36536
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42498
x-linked disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.115575
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
amino	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854278
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18637162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04028
onset	HPO Gene-Disease Associations	1.0	null
Perturb_5605_KD|OE_METTL1|RPTOR_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
L1CAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12821
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54148
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Eye-corneal epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	9.74913
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67286
metaraminol-2298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901622
Protruding Ear	DisGeNET Gene-Phenotype Associations	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	2.1381
Ocular albinism with sensorineural deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85113
Perturb_14645_KD_Ezh2_SRP269210	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the head	HPO Gene-Disease Associations	1.0	null
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69625
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.246
cSARS Bat SRBD_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6727
wide pore channel activity	GO Molecular Function Annotations 2023	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040796
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24348
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930386
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073587
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
BRD-K99416393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71039
abnormality of the lens	HPO Gene-Disease Associations	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31496
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A89H-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr1_34758711_T_G_b38	GTEx eQTL 2025	1.0	1.10749
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99752
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
Epidermolytic hyperkeratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.963
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16863
all	GeneRIF Biological Term Annotations	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39222
hsa-miR-1260	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891574
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00582
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69806
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03124
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Cornelia de Lange syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046808
Perturb_5526_KO_Crtc1_SRP279598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.7939
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05838
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal glucose homeostasis	HPO Gene-Disease Associations	1.0	null
BRD-K57357304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03861
Gap junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21673
Perturb_13090_KO_Atm_SRP062722	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01614
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02113
hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231206
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046129
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89402302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15711
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7914_KD_TOP1MT_SRP372079	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.43982
Clouston syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.999
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.670417
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC4783780__F8	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6872
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
PRKAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97211
H3K36me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HG-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14799
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51621
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71007
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20896
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36367
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	5.03476
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15059
metamizole sodium-2175	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51586
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K81779733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0113
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20184
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39512
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2038
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03905
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095237
BRD-K77498991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08966
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869813
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11915_KO_Rankl_SRP190820	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.40584
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22363
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of skin physiology	HPO Gene-Disease Associations	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3394
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.293
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.888829
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.855003
ACC3	BioGPS Cell Line Gene Expression Profiles	1.0	1.10667
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64366
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09217
BRD-K36627718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5879
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9146
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.85115
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52584
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW22	DepMap CRISPR Gene Dependency	1.0	3.0603
NCIH209	DepMap CRISPR Gene Dependency	1.0	3.88221
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22966
membrane part	GO Cellular Component Annotations 2015	1.0	null
BRD-K63909265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06108
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13251
Enlarged vestibular aqueduct	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27047
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19079
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13458
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.653807
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.259473
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34185
impairment	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51066
Charcot-Marie-Tooth disease type X	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
BRD-K54593730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37851
Syndactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
TCF3-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043046
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063747
MTDH_DEPLETION_GDS3179_98_human_LM2 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0841
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4642	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
abnormality of skull size	HPO Gene-Disease Associations	1.0	null
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
decreased body weight	HPO Gene-Disease Associations	1.0	null
BRD-K49473928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02639
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49177
T3M4	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.897853
Monilethrix	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95716
BRD-K65737790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4179
Perturb_13104_KO_Opa1_SRP404364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PRKAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53014
BRD-K54837058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51846
KM-H2	GDSC Cell Line Gene Expression Profiles	1.0	1.53954
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77159
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
22RV1	DepMap CRISPR Gene Dependency	1.0	2.55248
Lamina epithelialis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_79_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22949587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05949
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.555
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844312
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36417
hsa-miR-4494	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE248501_1_v_0_mst1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A41199690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6068
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50751
AKT1_knockdown_141_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.18659
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95251122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17309
other	GAD High Level Gene-Disease Associations	1.0	0.293278
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11192
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7297
Brachydactyly	DisGeNET Gene-Disease Associations	1.0	null
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66636
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04695
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Ca<sup>2+</sup>	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16872
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8710_OE_SMAD4_SRP255626	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.89079
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8221
hsa-miR-320b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
EPCAM_OE_GDS4887_343_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4896
Lung adenocarcinoma_LUAD_TCGA-05-4403-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HY-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1373	DepMap CRISPR Gene Dependency	1.0	4.27667
DCXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48923
ZBTB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35796
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51628
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19783
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978381
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075845
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14807
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14852
TFAP2C	ChEA Transcription Factor Targets	1.0	null
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23664
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80733
abnormal blistering of the skin	HPO Gene-Disease Associations	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.629
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32813
BRD-K80763723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19625
SRY-22984422-TESTIS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
GSE157050,GSE157051_2_v_9_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
6-chloromelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23759
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83774
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11753
hydrometra	IMPC Knockout Mouse Phenotypes	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86801
similarity	GeneRIF Biological Term Annotations	1.0	null
COLO201	DepMap CRISPR Gene Dependency	1.0	2.17497
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63267
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22886
Adult stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35096
CAOV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K82681356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01751
abnormality of the hair	HPO Gene-Disease Associations	1.0	null
BRD-K83916197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62978
BRD-K17910820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08771
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60559
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24281
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.982386
hsa-miR-331-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0895
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39508
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
Erythema	HuGE Navigator Gene-Phenotype Associations	1.0	null
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
dactinomycin_mus musculus_gpl1261_wild type_gds2456	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041582
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13829
BRD-K48557872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11938
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ebolavirus(EBOV)_5day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.01544
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26728
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09258
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Erythrokeratodermia Variabilis	DisGeNET Gene-Disease Associations	1.0	null
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78289
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10187
CLPP_KO_GSE40207_388_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83124
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.839248
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17208
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.50368
behavior	GO Biological Process Annotations 2015	1.0	null
Exanthema	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24447
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0686
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58586013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08074
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6893
BRD-K09863466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80743
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14253
Primary somatosensory area, mouth, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27675
hsa-miR-4493	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
unknown	GeneRIF Biological Term Annotations	1.0	null
KMRC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
doxorubicin_mus musculus_gpl8321_gse17115	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K16705434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07423
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22058
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068446
Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
trachea	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935922
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Bart-Pumphrey syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.949
missense	GeneRIF Biological Term Annotations	1.0	null
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
forearm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K56188606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9249
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98841
nuclear lumen	GO Cellular Component Annotations 2025	1.0	null
LPIN1_OE_GDS2291_587_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
enlarged uterus	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K57724551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74156
FOSL1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29145
gap junction	GO Cellular Component Annotations 2025	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3238
short digit	HPO Gene-Disease Associations	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17448
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13677
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43133
style	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326798
Gata-6_KO_GDS4782_330_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Vohwinkel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.937
GSE228181_0_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85720719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04563
Perturb_15309_Mut|OE|KD_Kras_SRP360531	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958684
Secondary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04047
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38961
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.061
gjb3	GeneRIF Biological Term Annotations	1.0	null
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059299
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Tectum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7288
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Calcium regulation in cardiac cells	WikiPathways Pathways 2024	1.0	null
LRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41948
RBBP5	ENCODE Transcription Factor Targets	1.0	null
RARA_01_51	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61775