association dataset threshold value standardized value superficial stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0009 1321N1 CCLE Cell Line Gene Expression Profiles -1.0 -1.72265 PTP4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26814 superficial stratum of FCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14044 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25632 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.805 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null CDX2-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE160083,GSE160084_1_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5K5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.897 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04164 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.070143 MYOG ENCODE Transcription Factor Targets 1.0 null Muscular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144 GSE241701_4_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null PITX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42503 Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09473 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.966 abnormal muscle morphology MPO Gene-Phenotype Associations 1.0 null decreased grip strength MGI Mouse Phenotype Associations 2023 1.0 null intermediate tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0009 SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.831066 DU4475 CCLE Cell Line Gene Expression Profiles 1.0 2.71942 LPIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71251 REST_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KLHDC7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63323 Xanthophore COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.657 ACOT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40562 ZNF404 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37638 cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.065374 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.857821 lateral group of nuclei, right, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03671 hematopoietic system phenotype MPO Gene-Phenotype Associations 1.0 null MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2549 FBXL15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88016 HUT78 CCLE Cell Line Gene CNV Profiles -1.0 -1.59231 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CI-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9513 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.47112 without GeneRIF Biological Term Annotations 1.0 null EW16 DepMap CRISPR Gene Dependency 1.0 2.76119 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.16113 Mammary myoepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.61 MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.90756 SQ1 CCLE Cell Line Gene CNV Profiles 1.0 1.80488 Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF12_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV434 CCLE Cell Line Gene Expression Profiles 1.0 1.77114 A-CA-04-2009(H1N1)_0Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.28298 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.876049 nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.96918 Medial habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04431 Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36019 TCAIM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3447 Inflammation CTD Gene-Disease Associations 1.0 1.11877 cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.945825 Vagina TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35092 Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Triangular nucleus of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46181 molecules GeneRIF Biological Term Annotations 1.0 null GSE48812_2_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null regulation of developmental growth GO Biological Process Annotations 2015 1.0 null Connexin, conserved site InterPro Predicted Protein Domain Annotations 1.0 null intercellular GeneRIF Biological Term Annotations 1.0 null H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHLA15 DepMap CRISPR Gene Dependency 1.0 4.26528 abnormal mononuclear phagocyte morphology MPO Gene-Phenotype Associations 1.0 null TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0494 RABGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90801 ventral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16932 SNU398 DepMap CRISPR Gene Dependency 1.0 2.70101 Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22939 HS 683 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31369 KDM2B-26808549-CHIP-SEQ-REH-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TRIB1_KO_GDS2944_555_mouse_Macrophages GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null caudal group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.943828 Sertoli cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.119 mantle zone of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6316 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.24388 Nucleus of the lateral lemniscus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02796 Perturb_18390_KO_923_SRP286259 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.98043 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100575_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16081 H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior pretectal nucleus, ventral superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0009 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.02631 NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7492 NCIH1339 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 SMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66886 TMEM147 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32698 secondary prosencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31849 Metencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-T5JC-0011-R1A-SM-32PM6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.94613 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PROCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16111 GSE198794_2_v_1_usp18_human RummaGEO Gene Perturbation Signatures 1.0 null Autosomal recessive nonsyndromic deafness 23 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.977 Hmx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.537 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H1-0 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42474 GTEX-NPJ7-2726-SM-2I3FT GTEx Tissue Sample Gene Expression Profiles 1.0 1.05561 SRC_activemutant_51_GSE15815 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.87198 TRIM28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38454 ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23128 A375SKINCJ3 DepMap CRISPR Gene Dependency 1.0 3.30242 ZNF420 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4481 Hypertension CTD Gene-Disease Associations 1.0 1.18424 gap junction GO Cellular Component Annotations 2025 1.0 null hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0824 TMK-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 MTRF1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47325 eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048481 CALML6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33064 Kidney Diseases CTD Gene-Disease Associations 1.0 1.08726 496100583_PCx_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.49612 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71065 GTEX-RNOR-0011-R7A-SM-2TF4V GTEx Tissue Sample Gene Expression Profiles 1.0 0.916401 trophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.317315 HS706T CCLE Cell Line Gene Expression Profiles -1.0 -1.90812 MSTO211H DepMap CRISPR Gene Dependency 1.0 2.10048 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 0.957262 GSE186440,GSE186443_1_v_5_daxx_human RummaGEO Gene Perturbation Signatures -1.0 null exchange GeneRIF Biological Term Annotations 1.0 null HEC1B DepMap CRISPR Gene Dependency 1.0 2.46 GTEX-NPJ8-1526-SM-2D7VU GTEx Tissue Sample Gene Expression Profiles 1.0 1.64031 Central amygdalar nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0471 Autosomal recessive nonsyndromic deafness 36 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.431 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2406 RAB1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60581 KCL-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.29135 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ITK_knockout_242_GSE12465 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.30268 Perturb_16393_KO_Barx2_SRP034552 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 wide pore channel activity GO Molecular Function Annotations 2023 1.0 null GSE120370_4_v_1_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ8I-2026-SM-4BOOL GTEx Tissue Sample Gene Expression Profiles 1.0 0.861457 molecular layer of S Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33757 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28546 ZNF566 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48042 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.836968 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05205 dorsal pallium/isocortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01031 ventral posterior inferior nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.76065 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPMI-7951 COSMIC Cell Line Gene Mutation Profiles 1.0 null Charcot-Marie-Tooth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.327 anterior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19031 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.862275 HCC2279 CCLE Cell Line Gene CNV Profiles -1.0 -1.45096 LTBR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51711 RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.834463 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.53339 Prostate adenocarcinoma_PRAD_TCGA-YL-A8S9-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5048 ventral posterior medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36132 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46707 SCAPER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34021 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54392 gap junction channel activity GO Molecular Function Annotations 2025 1.0 null dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.841419 TM31 CCLE Cell Line Gene Expression Profiles -1.0 -2.40204 ELOVL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02999 mantle zone of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14044 myotube TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.457987 CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11403 HDMYZ CCLE Cell Line Gene Expression Profiles -1.0 -2.14904 GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 1.26002 transfer GeneRIF Biological Term Annotations 1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.40133 RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1 Rummagene Transcription Factor Associations 2026 1.0 null MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877015 ZFP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07033 Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.4687 SNX22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31512 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UE-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hypertrophy CTD Gene-Disease Associations 1.0 1.28889 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0295 Neck TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1132 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911779 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63 Rummagene Transcription Factor Associations 2026 1.0 null Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.6197 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39878 KEAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08859 NFYA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2068 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41541 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.918363 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26879 orthologs GeneRIF Biological Term Annotations 1.0 null H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CRBN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40974 mouse GeneRIF Biological Term Annotations 1.0 null GTEX-Q2AG-0011-R8A-SM-2HMK5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.881279 Mammary myoepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.648 Superior central nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20022 COGE352 DepMap CRISPR Gene Dependency 1.0 2.83502 SUZ12 ENCODE Transcription Factor Targets 1.0 null Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1366 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-0006-SM-2XCFE GTEx Tissue Sample Gene Expression Profiles 1.0 0.948768 Pituicyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.574 HCC1428 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53936 ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65636 GSE166004_1_v_0_pld1_mouse RummaGEO Gene Perturbation Signatures 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050641 NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05413 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCZ1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68438 CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.895221 CBX8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell lysate TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.24676 gap junction GO Cellular Component Annotations 2023 1.0 null SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.62513 GTEX-T2IS-3026-SM-32QPM GTEx Tissue Sample Gene Expression Profiles 1.0 1.64037 Gap junction protein, cysteine-rich domain InterPro Predicted Protein Domain Annotations 1.0 null OB glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58007 BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1511 GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56871 LCLC97TM1 CCLE Cell Line Gene Expression Profiles -1.0 -2.04486 FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE110440_2_v_3_rad21_mouse RummaGEO Gene Perturbation Signatures 1.0 null TYK2_KD_GDS4754_158_human_JURKAT GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2452 CCLE Cell Line Gene CNV Profiles 1.0 1.84908 Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04253 Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0011-R3A-SM-4B64W GTEx Tissue Sample Gene Expression Profiles 1.0 1.81529 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CG-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T3M4 DepMap CRISPR Gene Dependency 1.0 5.06386 regulation of developmental process GO Biological Process Annotations 2015 1.0 null PKD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31307 Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82655 Nucleus of reunions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30481 intermediate stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.124 GTEX-WL46-2926-SM-3LK82 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2027 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 0.964732 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bronchoalveolar system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 medial orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24056 dorsolateral prefrontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05286 OE19 CCLE Cell Line Gene Expression Profiles 1.0 1.34734 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DQ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.7841 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.58547 WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31369 CORL88 CCLE Cell Line Gene CNV Profiles -1.0 -1.93524 gap junction COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.42248 PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null Usher syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 zygote TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.141214 PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3 Rummagene Transcription Factor Associations 2026 1.0 null Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12544 TRIM47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21098 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Necrosis CTD Gene-Disease Associations 1.0 1.55353 uterine cervix TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070708 CLPP_KO_GDS4791_541_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.828086 posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2816 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06958 superficial stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0009 Ventromedial hypothalamic nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2355 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33433 HS766T COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A8CN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IL13RA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71068 UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN ChEA Transcription Factor Targets 2022 1.0 null regulation of response to stress GO Biological Process Annotations 2015 1.0 null paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.943214 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051424 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049646 orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.908755 GSE225141,GSE225143_0_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null precentral gyrus, left, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.944131 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null TAOK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94613 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30787 lateral orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05547 GTEX-OXRK-0926-SM-2HMKP GTEx Tissue Sample Gene Expression Profiles 1.0 1.13185 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of cell activation GO Biological Process Annotations 2015 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00254 NOMO1 DepMap CRISPR Gene Dependency 1.0 3.56919 GSE164874_5_v_9_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null VCAN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15045 HOXC12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0927 MRTFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94999 Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles 1.0 0.904137 SNU503 CCLE Cell Line Gene CNV Profiles -1.0 -1.56992 GTEX-X4XX-0011-R3B-SM-46MWK GTEx Tissue Sample Gene Expression Profiles 1.0 1.27451 superficial stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12632 Perihypoglossal nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15291 intercostal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.37179 Anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31597 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 0.986615 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.2315 TRO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4896 spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.839801 protein complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.92769 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7348 orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62426 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gap junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.116 A3-KAW COSMIC Cell Line Gene Mutation Profiles 1.0 null PGAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98235 ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8664 Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20869 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.074955 COV644 DepMap CRISPR Gene Dependency 1.0 2.28712 adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.12582 GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles 1.0 0.916247 PDHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81637 Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.965098 GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26937 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Outer dense plaque of desmosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.755 FCHSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23948 Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.3651 basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13729 regulation of multicellular organismal process GO Biological Process Annotations 2015 1.0 null GTEX-WZTO-0011-R10B-SM-4E3KB GTEx Tissue Sample Gene Expression Profiles 1.0 1.72084 SNU5 DepMap CRISPR Gene Dependency 1.0 2.04117 ZFP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14469 hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13372 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2842 DHRS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02173 CCNT2 ENCODE Transcription Factor Targets 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7442 primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49401 IDH3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12572 Mus musculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05126 hsa-miR-3155b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53687 COQ7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96846 SUZ12 ChEA Transcription Factor Targets 1.0 null HNRNPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07198 SPTAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8119 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.60074 PWR-1E COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.4141 CLDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61987 Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormal hematopoiesis MPO Gene-Phenotype Associations 1.0 null GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null TNKS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53593 RGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10075 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.963892 NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39878 REL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46616 CCDC88A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12735 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.71897 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041064 Rectum adenocarcinoma_READ_TCGA-EI-6512-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37078 GSE148657_2_v_1_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null Membrane Trafficking Reactome Pathways 2024 1.0 null Gap junction trafficking and regulation Reactome Pathways 2024 1.0 null Clouston syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.6 primary auditory cortex (core)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21519 PC3 CCLE Cell Line Gene Expression Profiles 1.0 1.97385 ARL4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56362 ventral lateral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.867336 GSE137818_5_v_0_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54922 GTEX-QVJO-0011-R8A-SM-447C7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03278 CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05624 superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36746 RNF2 ENCODE Transcription Factor Targets 1.0 null YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.34827 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.08699 Interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40953 KMH2 CCLE Cell Line Gene Expression Profiles 1.0 1.39199 CGB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02565 C32 CCLE Cell Line Gene CNV Profiles -1.0 -1.32861 Pancreatic delta cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.717 Uterus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08056 MAFF ENCODE Transcription Factor Targets 1.0 null SCRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83542 Ventromedial hypothalamic nucleus, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02251 BCL2L13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17591 GTEX-NL3H-0011-R10A-SM-2I3E9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.49992 PC-3 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 Gap junction trafficking Reactome Pathways 2024 1.0 null INTS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25995 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72749 hsa-miR-3155 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 membrane part GO Cellular Component Annotations 2015 1.0 null 496100540_TCx_probable Alzheimer's disease_TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.24989 morula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.15144 GTEX-NL3H-0011-R3a-SM-2I3GL GTEx Tissue Sample Gene Expression Profiles 1.0 0.866664 H3K27me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100610_TCx_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.95201 Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1953 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.9332 Medial preoptic nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45232 Anterior hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71655 SW480 CCLE Cell Line Gene Expression Profiles 1.0 1.43097 GCT CCLE Cell Line Gene Expression Profiles 1.0 1.83978 PBX1 ChEA Transcription Factor Targets 1.0 null basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20641 TMEM161A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81045 Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null thorax TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072775 PMC9805873-Supp_Data.xlsx-dCas9-SALL1-SDS3_CD46_indiv-id_SALL1 Rummagene Transcription Factor Associations 2026 1.0 null decreased macrophage cell number MPO Gene-Phenotype Associations 1.0 null Fast muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.121 auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.582384 olfactory bulb, principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63669 WEHI-231 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.501 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1627 JAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61152 NCIH1930 CCLE Cell Line Gene CNV Profiles -1.0 -1.6368 CA2+ DGIdb Drug Targets 2026 1.0 0.322756 GTEX-OXRN-0011-R10A-SM-2I5GC GTEx Tissue Sample Gene Expression Profiles 1.0 1.01187 SLC16A7+ cell_Lung_Human CellMarker Gene-Cell Type Associations 1.0 null ICC12 DepMap CRISPR Gene Dependency 1.0 3.14369 TP53 JASPAR Predicted Transcription Factor Targets 1.0 null RCHACV CCLE Cell Line Gene Expression Profiles -1.0 -1.94021 superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.880025 PHF8-20622853-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null plasma membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 KURAMOCHI CCLE Cell Line Gene CNV Profiles 1.0 1.62963 regulation of response to external stimulus GO Biological Process Annotations 2015 1.0 null cervical adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.116819 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.964857 LCMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99876 principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.838294 HOXC9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1987 abnormal professional antigen presenting cell morphology MPO Gene-Phenotype Associations 1.0 null CEBPB JASPAR Predicted Transcription Factor Targets 1.0 null Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56629 GTEX-WRHU-0826-SM-3MJFN GTEx Tissue Sample Gene Expression Profiles 1.0 1.48602 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12334 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997837 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.13792 CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31695 TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ8-0011-R10A-SM-2YUMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.78981 ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44464 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TTLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03314 FLUFENAMIC ACID DGIdb Drug Targets 2026 1.0 0.348237 DCBLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02665 Gap junction trafficking Reactome Pathways 2014 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00181 cochlear nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01236 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Simple lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27842 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R2-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36257 BICR18 CCLE Cell Line Gene CNV Profiles -1.0 -1.588 internal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50957 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28546 regulation of response to wounding GO Biological Process Annotations 2015 1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Plasma membrane protein complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 ADAM10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12608 GSE164874_5_v_4_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null Esophagitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.005 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3094 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69661 Anteroventral periventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33784 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93798 regulation of growth GO Biological Process Annotations 2015 1.0 null VPS26B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88578 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929744 GSE198794_2_v_3_usp18_human RummaGEO Gene Perturbation Signatures 1.0 null PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7539 ZSCAN25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17473 Internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09309 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042095 Gap junction trafficking and regulation Reactome Pathways 2014 1.0 null GSE133329_0_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 0.841101 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.905239 Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.849224 Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cervical carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.086478 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CK-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-11A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased macrophage cell number MGI Mouse Phenotype Associations 2023 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24827 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 0.893474 increased circulating sodium level IMPC Knockout Mouse Phenotypes 1.0 null Main olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03101 Lens epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.935 Sarcoglycan complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.705 CUX1 ChEA Transcription Factor Targets 1.0 null GTEX-T6MN-2626-SM-32PMQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.47141 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.925302 GTEX-R55E-0011-R1A-SM-2TC6N GTEx Tissue Sample Gene Expression Profiles 1.0 1.44477 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889937 soft tissue HPA Tissue Protein Expression Profiles -1.0 -0.805785 KMS12BM CCLE Cell Line Gene CNV Profiles 1.0 1.50953 JUND_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.28364 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE255432_7_v_0_imeglimin_mouse RummaGEO Drug Perturbation Signatures 1.0 null STRADA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02117 GTEX-R55E-0011-R4A-SM-2TC5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.25712 SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.87761 Prostate adenocarcinoma_PRAD_TCGA-HC-8260-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86265 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AG-0011-R3A-SM-2HMJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.79383 RPL39L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75658 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.907584 HOXB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94591 ATN-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.126149 Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7171 496100482_PCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.37493 tcof1_15522210_neuroblastoma_gof_mouse_gpl339_gds998 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.063996 GSE164874_5_v_10_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null Paraventricular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18008 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GANAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22685 Anteroventral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09585 GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles 1.0 0.865507 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU475 CCLE Cell Line Gene CNV Profiles 1.0 1.5004 Ca2+ Guide to Pharmacology Chemical Ligands of Receptors 1.0 null ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.9369 NCIH1155 CCLE Cell Line Gene CNV Profiles -1.0 -1.39358 CXorf38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52222 CAPN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16955 GTEX-T5JC-0011-R2A-SM-32PLZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.989303 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041305 253J DepMap CRISPR Gene Dependency 1.0 2.55318 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3595 HT144SKINFV1 DepMap CRISPR Gene Dependency 1.0 2.44269 GDF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86365 LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.904588 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TM-4 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.129 PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-gen-Down-Symbol_ZBTB16 Rummagene Transcription Factor Associations 2026 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.12244 Deprivation amblyopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.318 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.2159 forebrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27327 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912381 GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles 1.0 1.14833 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.00951 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.4437 GTEX-T5JC-0011-R10A-SM-32PM2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.87898 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.61619 CSNK1G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51519 SJRH30 CCLE Cell Line Gene Expression Profiles 1.0 1.9588 PHGDH_KO_GDS2874_125_mouse_embryonic head tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11481 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.835909 GTEX-T5JC-0011-R8A-SM-32PLM GTEx Tissue Sample Gene Expression Profiles 1.0 1.7521 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.32731 Myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.149 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16086 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.90353 LARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28371 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MON1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0845 SCCOHT1 DepMap CRISPR Gene Dependency 1.0 3.82988 Ventromedial hypothalamic nucleus, dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19318 cell communication KEGG Pathways 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36295 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.10396 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.5565 REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6364 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PPARGC1A_KO_GDS2391_299_mouse_brain striatum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.857821 Brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 JUND ENCODE Transcription Factor Targets 1.0 null PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null Ventral premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49853 Eosinophilic esophagitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.005 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06021 retinal degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.388166 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.00884 Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39878 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.068049 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BATF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4395 intermediate stratum of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12632 EXD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08678 CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.62336 cell culture TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066018 Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.812 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046176 adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055588 Hepatomegaly CTD Gene-Disease Associations 1.0 1.15189 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.857821 GSE123105,GSE124556_0_v_2_pcf11_human RummaGEO Gene Perturbation Signatures 1.0 null BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.277 centromedian nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.955592 Lobule II, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10543 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.826163 Intercalated disc COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.943 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 53.8016 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.00412 MRM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67887 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22866 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARVCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97977 layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1195 GTEX-WZTO-0011-R3B-SM-3NMC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0664 H3-3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00118 Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS27 DepMap CRISPR Gene Dependency 1.0 4.77294 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_12Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.99827 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BOK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95923 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 57.6982 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4915 GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 1.59371 NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-X585-0011-R2B-SM-46MVF GTEx Tissue Sample Gene Expression Profiles 1.0 1.18031 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 0.950777 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 0.899827 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62606 GSE149075_3_v_5_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null cx43expressing GeneRIF Biological Term Annotations 1.0 null Anchoring junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SCG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09765 HEC265 DepMap CRISPR Gene Dependency 1.0 2.34751 DB CCLE Cell Line Gene Expression Profiles 1.0 1.39371 Bardet-Biedl syndrome 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.452 EP300_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.303 GSE139975_3_v_0_rnf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null parafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36016 647V DepMap CRISPR Gene Dependency 1.0 2.68802 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4054 Autosomal recessive nonsyndromic deafness 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 ZNF432 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61925 RABEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98313 Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22544 KDM6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73208 TEAD4 ENCODE Transcription Factor Targets 1.0 null NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.964857 primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.906877 CORL279 DepMap CRISPR Gene Dependency 1.0 2.71893 GLIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.1803 plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.048629 SUM190PT DepMap CRISPR Gene Dependency 1.0 4.55335 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37398 Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36948 Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34935 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4338 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29211 abnormal macrophage morphology MPO Gene-Phenotype Associations 1.0 null abnormal leukocyte cell number MPO Gene-Phenotype Associations 1.0 null Lung adenocarcinoma_LUAD_TCGA-NJ-A4YQ-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MORCPR CCLE Cell Line Gene Expression Profiles 1.0 1.51697 liver BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.16148 Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.2344 Fatty Liver CTD Gene-Disease Associations 1.0 1.30299 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.59976 GTEX-WHSE-0011-R2A-SM-3P5ZL GTEx Tissue Sample Gene Expression Profiles 1.0 0.839632 NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Limbic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5588 middle frontal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.831281 hsa-miR-371-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 central nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2227 THP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.89085 EB2 COSMIC Cell Line Gene Mutation Profiles 1.0 null enhanced skeletal muscle regeneration MGI Mouse Phenotype Associations 2023 1.0 null MAFF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X261-0011-R10B-SM-4E3JT GTEx Tissue Sample Gene Expression Profiles 1.0 0.844276 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null granule cell layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.182 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31369 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.21126 Ventromedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1689 ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4382-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null SSBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9576 outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15028 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050967 SLC18B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78651 VMRCLCP CCLE Cell Line Gene Expression Profiles -1.0 -1.50619 Lobule II, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25247 GTEX-R55E-0011-R8A-SM-2TC66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15091 TSHZ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83656 inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27493 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HZ-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gap junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.409479 dorsal lateral geniculate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12521 EFO-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.8108 Temporal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.2216 TBL1-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EFM19 DepMap CRISPR Gene Dependency 1.0 2.57242 Proteasome storage granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.621 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5349 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NP-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.963 CXCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44312 GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.0691 FAM135A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5834 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 regulation of multicellular organismal development GO Biological Process Annotations 2015 1.0 null Connexin InterPro Predicted Protein Domain Annotations 1.0 null ZNF722 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77897 KLM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.84216 connexon complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3872 Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57556 Perturb_18391_KO_923_SRP286259 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.26447 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13563 HDQP1 CCLE Cell Line Gene CNV Profiles 1.0 1.82389 cell-cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Hindbrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 differ GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP2 ChEA Transcription Factor Targets 1.0 null superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33115 RAI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64977 COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.894714 Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 2 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0845 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endometrial luminal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.648 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8361 FOXO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64776 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.89748 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050627 DUSP1_Deficiency_GDS1606_765_mouse_Spleen GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null MDAMB453 DepMap CRISPR Gene Dependency 1.0 2.70295 Umbilical vein endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.2 REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7059 CESS cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.677 MSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51117 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 54.7 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Melanophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.781 JUND-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null layer 2 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50134 ZNF485 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86183 NCIH716 CCLE Cell Line Gene CNV Profiles 1.0 1.47693 GTEX-XLM4-0011-R10A-SM-4AT5P GTEx Tissue Sample Gene Expression Profiles 1.0 1.09948 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17265 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3 Rummagene Transcription Factor Associations 2026 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF12/HEB-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Vesicle-mediated transport Reactome Pathways 2024 1.0 null ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6423 AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32782 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05158 MLH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72213 mantle zone of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0009 GSE133213_6_v_15_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE210662_3_v_1_znf165_human RummaGEO Gene Perturbation Signatures -1.0 null GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8522 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15194 GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 1.46425 GSE164874_5_v_3_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null connexin complex GO Cellular Component Annotations 2023 1.0 null GTEX-S7SE-0011-R2A-SM-2XCDC GTEx Tissue Sample Gene Expression Profiles 1.0 0.981705 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5522 GTEX-PLZ6-1526-SM-2S1OC GTEx Tissue Sample Gene Expression Profiles 1.0 0.827236 IRX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97114 cell communication GO Biological Process Annotations 2015 1.0 null ZNF497 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92643 PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 0.825163 STX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71861 inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.986382 biological regulation GO Biological Process Annotations 2015 1.0 null NANOGNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45501 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8077 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100557_TCx_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05494 JUND_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067475 H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDCA7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61215 abnormal mononuclear cell morphology MPO Gene-Phenotype Associations 1.0 null single-organism cellular process GO Biological Process Annotations 2015 1.0 null SARS-BatSRBD_Day1_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.8721 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20F-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null red nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21368 Edema CTD Gene-Disease Associations 1.0 1.16967 OCTANOL DGIdb Drug Targets 2026 1.0 0.630143 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01615 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46875 Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18964 HOXD11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0683 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-661 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.84797 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31281 EZH2 ENCODE Transcription Factor Targets 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8340-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205163,GSE205164_1_v_8_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null medial part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05334 Foxf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.1005 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01743 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04806 POU2F2 ENCODE Transcription Factor Targets 1.0 null GTEX-XLM4-3026-SM-4AT6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.3621 PCNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43415 SLMAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30909 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14636 TTC642 DepMap CRISPR Gene Dependency 1.0 3.85507 Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.5693 GTEX-N7MS-0011-R10A-SM-2HMJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.71528 PRKRIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9559 decreased grip strength IMPC Knockout Mouse Phenotypes 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10922 lateral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5667 single-organism process GO Biological Process Annotations 2015 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96566 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.78192 ITLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.363 Internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 intermediate stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0335 GTEX-QDT8-0011-R10A-SM-32PKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.66507 heart GTEx Tissue Gene Expression Profiles -1.0 -1.09206 lung HPA Tissue Protein Expression Profiles -1.0 -0.805785 GATA2 ENCODE Transcription Factor Targets 1.0 null abnormal muscle physiology MPO Gene-Phenotype Associations 1.0 null HAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52291 Major island of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76742 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11403 Lens fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.136 Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD4-25478319-HGPS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Culmen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12069 GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALDOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56273 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_0Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.895498 either GeneRIF Biological Term Annotations 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912381 connexin40 GeneRIF Biological Term Annotations 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HHIPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85888 IM95 CCLE Cell Line Gene Expression Profiles 1.0 1.78143 MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null macromolecular complex GO Cellular Component Annotations 2015 1.0 null PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1 Rummagene Transcription Factor Associations 2026 1.0 null A253 DepMap CRISPR Gene Dependency 1.0 5.17961 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.47536 NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6696 TMED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6597 NCIH716 DepMap CRISPR Gene Dependency 1.0 2.60374 SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4575 Copula pyramidis, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32317 HCC1937 DepMap CRISPR Gene Dependency 1.0 2.00596 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.29586 APELA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35762 layer 2 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03935 GLUL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22583 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10423 eye and adnexa disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047314 Central lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00423 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.999328 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.23013 Epididymis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092369 Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.919122 NCIH460 DepMap CRISPR Gene Dependency 1.0 2.74432 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13072 TMEM218 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15671 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44621 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 0.852653 AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.961913 Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17364 HL60 CCLE Cell Line Gene Expression Profiles 1.0 2.37743 OCIAML3 CCLE Cell Line Gene Expression Profiles 1.0 1.37584 NCIH1155 CCLE Cell Line Gene Expression Profiles -1.0 -1.66466 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.050604 BT-20 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32891 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.5576 GTEX-N7MS-0011-R3a-SM-33HC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.67351 HUH7 CCLE Cell Line Gene CNV Profiles -1.0 -1.55103 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30168 NCIH196 CCLE Cell Line Gene CNV Profiles 1.0 2.33094 MAP3K6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65961 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RDES DepMap CRISPR Gene Dependency 1.0 3.15585 neural plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05334 HARA COSMIC Cell Line Gene Mutation Profiles 1.0 null Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37629 inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.838669 cell part GO Cellular Component Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null connexin complex GO Cellular Component Annotations 2025 1.0 null Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CTTNBP2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0107 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12566 Muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144 NR3C1 ChEA Transcription Factor Targets 1.0 null Throat TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7958 hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.945518 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2106 abnormal leukocyte morphology MPO Gene-Phenotype Associations 1.0 null lateral posterior nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990573 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00254 KLF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26999 SPRYD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45485 carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051509 LU99 CCLE Cell Line Gene CNV Profiles 1.0 1.39391 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55016 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957 blastomere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.147924 retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.218034 Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80981 Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01675 affecting GeneRIF Biological Term Annotations 1.0 null UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144 anteroventral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.924903 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72689 Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07463 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.97678 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XX-0011-R8B-SM-46MWM GTEx Tissue Sample Gene Expression Profiles 1.0 1.22792 GSE151782_2_v_0_aim2_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100565_FWM_probable Alzheimer's disease_TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04363 superficial stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02178 mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37404 SNU201 DepMap CRISPR Gene Dependency 1.0 2.16584 MOLT16 CCLE Cell Line Gene Expression Profiles -1.0 -1.76138 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22139 Lung squamous cell carcinoma_LUSC_TCGA-77-8153-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 16715129-SuppTable5 GeneSigDB Published Gene Signatures 1.0 null regulation of wound healing GO Biological Process Annotations 2015 1.0 null LPCAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81917 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.852102 cx401 GeneRIF Biological Term Annotations 1.0 null DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05575 LCORL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23731 CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4215 wide pore channel activity GO Molecular Function Annotations 2025 1.0 null GSE231720,GSE231724_2_v_0_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null SPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48728 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.977946 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_0Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.50212 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40959 abnormal hematopoietic cell number MPO Gene-Phenotype Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7742-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13682 RC-K8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36914 satellite cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.677395 DNAAF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93347 GTEX-NPJ7-0011-R8a-SM-2I3G2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.47994 abnormal blood cell morphology/development MPO Gene-Phenotype Associations 1.0 null TSPAN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02196 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.11958 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.843628 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF37A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23222 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.873885 OB inner plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.80431 HEC251 DepMap CRISPR Gene Dependency 1.0 2.0097 USP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86281 ZNF410 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5004 NCIH841 CCLE Cell Line Gene Expression Profiles -1.0 -1.62092 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889665 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051479 E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80156 GTEX-P4PP-2026-SM-3P61N GTEx Tissue Sample Gene Expression Profiles 1.0 1.26857 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065762 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0734 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7842-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13353 layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42748 layer 5 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05945 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.03313 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2838 PTPN13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98953 FGF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23691 CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HCC70 CCLE Cell Line Gene CNV Profiles 1.0 2.18486 HUH6 CCLE Cell Line Gene Expression Profiles -1.0 -1.65171 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46356 membrane LOCATE Predicted Protein Localization Annotations 1.0 null pineal_night BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.909986 Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nodulus (X), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04745 dorsal peduncular cortex, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.124 NCOA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4769 STUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44342 eRF1 methyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.833 HOXB9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6824 REEP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05389 middle frontal gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07502 Female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cx37 GeneRIF Biological Term Annotations 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null MAPK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35964 Arcuate hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38722 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.964857 Dinoflagellate cingulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.985 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU245 CCLE Cell Line Gene Expression Profiles 1.0 1.4351 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6702 GTEX-PVOW-2526-SM-2XCF7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50573 sex chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.54606 CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20807 GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 0.944123 TAL1 ENCODE Transcription Factor Targets 1.0 null RAB4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60698 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33422 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100650_TCx_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.60921 SUZ12_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null substantia nigra, compact part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.923787 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.02676 intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02948 JUN-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NKM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGFBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75271 Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28973 Sarcoma_SARC_TCGA-FX-A3TO-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XX-3026-SM-3NMB2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.72214 Copula pyramidis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20113 caudal secondary prosencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29103 GSE193588_3_v_2_pax3_mouse RummaGEO Gene Perturbation Signatures -1.0 null KLF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56818 GSE145215_0_v_3_krt13_mouse RummaGEO Gene Perturbation Signatures 1.0 null MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of skeletal muscle tissue regeneration GO Biological Process Annotations 2015 1.0 null SARS-BatSRBD_Day4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.89485 orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29475 HNF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99249 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2917 Skin TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TWSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50776 insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37078 Membrane Trafficking Reactome Pathways 2014 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH727 CCLE Cell Line Gene Expression Profiles -1.0 -1.6491 MES-SA COSMIC Cell Line Gene Mutation Profiles 1.0 null outer CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.835378 occipito-temporal gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10371 COLO792 CCLE Cell Line Gene Expression Profiles 1.0 1.55067 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3158 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.94018 intermediate stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13099 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.51489 RNF2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Apocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.791 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.9346 SRRD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22713 FGFRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57037 Lung adenocarcinoma_LUAD_TCGA-L4-A4E5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA1, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08013 GTEX-QVJO-0011-R4A-SM-2S1QL GTEx Tissue Sample Gene Expression Profiles 1.0 0.827607 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7857 Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20358 vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077739 496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.36739 XBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52227 EB1 CCLE Cell Line Gene Expression Profiles 1.0 1.7926 SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOGGUVW CCLE Cell Line Gene Expression Profiles -1.0 -1.59857 reticular formation of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12632 GTEX-OXRN-2426-SM-2I5EQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.20841 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15787 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Prostate adenocarcinoma_PRAD_TCGA-Y6-A8TL-01A-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3674 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Oculodentodigital dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.516 GTEX-WHSE-3026-SM-3P5ZH GTEx Tissue Sample Gene Expression Profiles 1.0 1.27122 SLC16A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15572 Eccrine sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.995 KMS-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sarcoma_SARC_TCGA-SG-A6Z4-01A-22R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sertoli cell-only syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 FOXP2-21765815-NEURO2A-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAGI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58319 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7395 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null connexon complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.30014 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044549 immune system phenotype MPO Gene-Phenotype Associations 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-8660-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARHGAP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82534 superficial stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37078 RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 0.922588 gap junction channel activity GO Molecular Function Annotations 2023 1.0 null cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.77914 IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7685 lateropallial prepiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6316 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.24476 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053585 SORBS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87988 Cell surface furrow COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.968 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.25045 hsa-miR-1225-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 ARID3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95479 diaphragm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.65056 anterior olfactory area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0009 Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-371-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Striated muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.954 TMBIM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82525 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Neuromuscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.19 SH10TC CCLE Cell Line Gene CNV Profiles 1.0 1.44739 medial mammillary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.935765 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39667 Cerebellum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2014 SNU213 CCLE Cell Line Gene Expression Profiles -1.0 -1.60794 HOXC11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3589 Dorsal tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93877 MTARC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78623 GTEX-QVJO-1426-SM-2S1QY GTEx Tissue Sample Gene Expression Profiles 1.0 1.35691 CDAN1_02_197 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.16993 D458 DepMap CRISPR Gene Dependency 1.0 4.09669 RB1_KD_GSE50532_627_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61569 precommissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26455 Umbilical vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.886 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.35843 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.958099 Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40616 PMC3419980-leu201249x4.xls-POLII-RUNX1ETO_peaks_2fold-All_gene_regions_having_RUNX1_ETO_peaks_genes_where_PolII_changes_more_than_2-fold_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21326 GSE132694,GSE132717_0_v_2_meis1_human RummaGEO Gene Perturbation Signatures -1.0 null MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3232 Hyperplasia CTD Gene-Disease Associations 1.0 1.32905 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.61389 Connexin complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11439 QKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83771 CD63 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49011 GTEX-XOTO-0011-R8A-SM-4B65J GTEx Tissue Sample Gene Expression Profiles 1.0 0.853002 Posterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30227 retinitis pigmentosa DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.754934 NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null liver HPA Tissue Protein Expression Profiles -1.0 -0.805785 PIP4K2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54834 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)_24Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.53832 GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.82384 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SL-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CARMIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05381 FOXP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79554 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.29673 N4BP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29388 HS939T CCLE Cell Line Gene CNV Profiles -1.0 -1.3512 Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.9565 GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41256 GTEX-QVUS-2826-SM-3GADB GTEx Tissue Sample Gene Expression Profiles 1.0 1.41163 GTEX-WZTO-0011-R4A-SM-3NMC7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26903 LCOR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76563 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0717 nucleus of the diagonal band, left, horizontal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.10439 hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26312 GTEX-WVLH-0011-R10A-SM-3MJFM GTEx Tissue Sample Gene Expression Profiles 1.0 1.54825 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13563 Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40674 Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.8968 HUNS1 DepMap CRISPR Gene Dependency 1.0 4.67001 EDRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84817 GSE120336_1_v_2_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null MYOG_myocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARMCX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06714 NCIH441 CCLE Cell Line Gene Expression Profiles 1.0 1.40134 GTEX-WVLH-0011-R2A-SM-3MJFJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.50084 carbenoxolone Guide to Pharmacology Chemical Ligands of Receptors 1.0 null Gap junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 ISG20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61431 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4721 RHOB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92174 U266B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.67891 Midbrain raphe nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43541 Nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.559 Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-635 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 BEN CCLE Cell Line Gene Expression Profiles -1.0 -2.99888 DIRAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30832 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.00313 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10776 KE39 CCLE Cell Line Gene CNV Profiles -1.0 -2.33158 VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.70896 Ventromedial hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29672 BT20 CCLE Cell Line Gene CNV Profiles 1.0 2.55154 Skin - Not Sun Exposed (Suprapubic) GTEx Tissue Gene Expression Profiles 2023 1.0 4.24356 ZNF208 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6389 IRX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88158 GTEX-X585-3026-SM-46MWF GTEx Tissue Sample Gene Expression Profiles 1.0 1.34353 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957 GSE48812_9_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null ES5 DepMap CRISPR Gene Dependency 1.0 2.73375 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null ANKRD17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57371 NABP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05339 Perireunensis nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63048 adrenal gland GTEx Tissue Gene Expression Profiles -1.0 -1.31305 TMSB4X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83614 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.24965 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.03631 SUPM2 CCLE Cell Line Gene Expression Profiles 1.0 1.46486 regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Merocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.995 Mammillary body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49731 G84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68145 Supramammillary nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51084 GTEX-NL4W-0011-R10A-SM-2I3DY GTEx Tissue Sample Gene Expression Profiles 1.0 0.928322 iPS-20b Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.38793 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC461 DepMap CRISPR Gene Dependency 1.0 5.23101 globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.957358 tRNA (m2G10) methyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.838 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.986197 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11439 HEPG2 DepMap CRISPR Gene Dependency 1.0 2.39747 GTEX-T2IS-0011-R3A-SM-32QPB GTEx Tissue Sample Gene Expression Profiles 1.0 1.37394 Liver Diseases CTD Gene-Disease Associations 1.0 1.08478 SNU216 DepMap CRISPR Gene Dependency 1.0 8.7546 abnormal immune system morphology MPO Gene-Phenotype Associations 1.0 null Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Z chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.169 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null plasma membrane part GO Cellular Component Annotations 2015 1.0 null abdominal adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.489838 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23886 el2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.851 UBALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17344 LIG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8098 some GeneRIF Biological Term Annotations 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.13449 Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02113 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.02815 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.01814 GATA6-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36948 thorax muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.595656 NPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3391 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.855219 Cognition Disorders CTD Gene-Disease Associations 1.0 1.10353 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ABI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34139 GSE118939_1_v_0_nras_human RummaGEO Gene Perturbation Signatures 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2459 epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052399 ZNF614 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23718 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Myoepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.895 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.975776 SUDHL8 CCLE Cell Line Gene Expression Profiles 1.0 1.39001 Dorsal nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39166 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X5-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2281 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBC1D13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41185 Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.6149 Intercostal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.058 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null octanol Guide to Pharmacology Chemical Ligands of Receptors 1.0 null CXXC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30564 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null connexon complex GO Cellular Component Annotations 2015 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.04923 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04961 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57373 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20302 dorsolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49535 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null MICOS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90259 TESK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97193 Midline group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2029 olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.840115 blastocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.442962 GSE94814_2_v_3_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.34799 TCF12 ENCODE Transcription Factor Targets 1.0 null UMRC6 CCLE Cell Line Gene Expression Profiles 1.0 1.80435 DANG CCLE Cell Line Gene CNV Profiles 1.0 1.88686 inferior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38832 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CLPP_KO_GSE40207_382_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.933369 ALS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10447 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13945 Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precentral gyrus, right, superior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.854903 RH30 CCLE Cell Line Gene Expression Profiles 1.0 2.99333 PRKAA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64492 reticular formation of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22863 GTEX-QVUS-0011-R4A-SM-3GAE7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.930132 layer 2 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31849 hela cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.277549 MHHNB11 DepMap CRISPR Gene Dependency 1.0 3.24455 Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.9945 Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GJA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01297 lateral part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1574 DNASE1L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70781 GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles 1.0 1.27751 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.834421 Parathyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 pituitary GTEx Tissue Gene Expression Profiles 1.0 1.17675 ELL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40135 CAAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32176 624 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11526 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6702 increased satellite cell number MGI Mouse Phenotype Associations 2023 1.0 null Parkin_OE_GDS4476_55_human_U87MG GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22986 cell-cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.074642 TUSC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9587 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23028 EP300 ENCODE Transcription Factor Targets 1.0 null BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.15557 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.894714 Uterine endometrium TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC Rummagene Transcription Factor Associations 2026 1.0 null ITPRIPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07869 EEIG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42982 Decidual stromal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.9 cervical cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.09326 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.865923 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00181 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.894708 abnormal immune system cell morphology MPO Gene-Phenotype Associations 1.0 null Dorsomedial nucleus of the hypothalamus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21559 mantle zone of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62673 OBSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40225 LB373-MEL-D COSMIC Cell Line Gene Mutation Profiles 1.0 null Main olfactory bulb, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04815 RMGI CCLE Cell Line Gene Expression Profiles 1.0 1.71759 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.15006 GTEX-S4UY-1426-SM-4AD6Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.2325 regulation of satellite cell activation involved in skeletal muscle regeneration GO Biological Process Annotations 2015 1.0 null Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.4765 JHUEM1 DepMap CRISPR Gene Dependency 1.0 3.01337 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.5661 Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA1, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23673 TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6155 abnormal myeloid leukocyte morphology MPO Gene-Phenotype Associations 1.0 null superficial stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13805 Field CA1, stratum lacunosum-moleculare Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20775 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.969202 Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30817 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.76689 Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06722 HDAC2 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHRNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8056 SUPT1 DepMap CRISPR Gene Dependency 1.0 2.31268 GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 0.956472 cervix uteri GTEx Tissue Gene Expression Profiles 1.0 0.95978 GTEX-XLM4-0011-R3B-SM-4AT6E GTEx Tissue Sample Gene Expression Profiles 1.0 1.06374 Autosomal recessive nonsyndromic deafness 35 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.494 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050379 CBX3 ENCODE Transcription Factor Targets 1.0 null KYSE-510 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16522 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.866308 ABRAXAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12141 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46707 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3478 Adrenocortical carcinoma_ACC_TCGA-OR-A5KO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COQ8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51311 ZNF382 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.9998 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11306 18438415-SuppData GeneSigDB Published Gene Signatures 1.0 null GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 1.33189 ZNF317 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5879 PRKAG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18095 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.731 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01386 SU-DHL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1756 abnormal hematopoietic system morphology/development MPO Gene-Phenotype Associations 1.0 null brain HPA Tissue Gene Expression Profiles 1.0 0.908318 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65288 DRAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63368 integral component of membrane GO Cellular Component Annotations 2015 1.0 null H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.08505 decreased hematopoietic cell number MPO Gene-Phenotype Associations 1.0 null uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058163 monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.05386 Esophagus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 increased satellite cell number MPO Gene-Phenotype Associations 1.0 null GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)_7Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.01412 GTEX-XOTO-0011-R1B-SM-4B65C GTEx Tissue Sample Gene Expression Profiles 1.0 0.98332 SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null intermediate gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73874 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.16101 MORCPR CCLE Cell Line Gene CNV Profiles 1.0 1.51033 SLR23 CCLE Cell Line Gene Expression Profiles 1.0 1.89832 ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72727 biological_process GO Biological Process Annotations 2015 1.0 null AKAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34636 GTEX-RNOR-0011-R4A-SM-3GAD3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.957365 GSE183994_3_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null flufenamic acid Guide to Pharmacology Chemical Ligands of Receptors 1.0 null Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24394 Periventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52453 Cerebral lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K27ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.8088 adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0523 mantle zone of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1574 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.005 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46919 ZFTRAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89925 cx302 GeneRIF Biological Term Annotations 1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9128 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANKS1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64123 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PNKD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53877 Forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-S4Q7-1426-SM-3K2B9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.948479 layer 3 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3442 TMEM92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7817 Prelimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22341 muscle phenotype MPO Gene-Phenotype Associations 1.0 null intermediate stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.06279 Nobox JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.4211 central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.874385 Muscle-endothelial cell of vascular tree Tabula Sapiens Gene-Cell Associations 1.0 1.19143 shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0335 SART1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60364 GSE201042_2_v_1_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lateral ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 LYPLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60981 nucleus coeruleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48606 KP-N-RT-BM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.26124 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BPNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27341 olfactory part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34892 SMAD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74283 Weight Loss CTD Gene-Disease Associations 1.0 1.13143 outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16601 H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-A4JF-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null PK8 DepMap CRISPR Gene Dependency 1.0 2.03399 Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abdomen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.106174 POU2F2_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892327 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041532 HTC-C3 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormal macrophage cell number MPO Gene-Phenotype Associations 1.0 null Nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22485 ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24015 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A185-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 trophectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.828616 Esophageal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.005 Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.574 Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.3876 Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 3.03991 CLCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72177 MPI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32755 MEX3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29703 KIAA1191 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27531 Cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SAR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37969 abnormal phagocyte morphology MPO Gene-Phenotype Associations 1.0 null GTEX-NL3H-0011-R2a-SM-2I3GG GTEx Tissue Sample Gene Expression Profiles 1.0 0.961742 Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02626 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.1322 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.22944 GSE165174,GSE165175_0_v_1_trametinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null Central linear nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55057 DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -2.5356 reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63069 PRR11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22388 sublayer 6b of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28215 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03966 Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null INA6 DepMap CRISPR Gene Dependency 1.0 2.28528 ZNF121 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55748 RKO-E6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03963 Telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 mantle zone of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0009 SUCLG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65753 ventral tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27619 MRPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39965 NCIH524 CCLE Cell Line Gene CNV Profiles -1.0 -1.48086 Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferior frontal gyrus, orbital part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.973645 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAPK8IP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07778 hsa-miR-5095 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 NFYA-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Median preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22241 NFYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8168 SW1573 CCLE Cell Line Gene Expression Profiles -1.0 -2.7665 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.957758 HUNS1 CCLE Cell Line Gene Expression Profiles 1.0 1.47428 SLC27A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8402 GTEX-QLQ7-0826-SM-447B3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.825341 medial geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78597 Dentate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00557 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30481 usher syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.11603 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null CDIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89769 dorsal subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92444 Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062714 intermediate white layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00838 Autosomal recessive nonsyndromic deafness 12 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.061 Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02964 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC38A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58192 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X585-0011-R10A-SM-46MUY GTEx Tissue Sample Gene Expression Profiles 1.0 1.32376 Lung adenocarcinoma_LUAD_TCGA-95-A4VN-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53324 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00298 PJA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30598 Bronchus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-WZTO-2926-SM-3NM9I GTEx Tissue Sample Gene Expression Profiles 1.0 1.56007 YSCCC DepMap CRISPR Gene Dependency 1.0 2.64916 OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01597 Bed nucleus of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57135 KDSR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94234 foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.037887 superficial stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78597 HNFA-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.101446 Lung TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null INF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09865 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06047 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898155 embryonic fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.477367 Copula pyramidis, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11283 GTEX-TSE9-0011-R10A-SM-3DB7O GTEx Tissue Sample Gene Expression Profiles 1.0 1.36184 HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 2.06317 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14261 CARNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70561 epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051439 MYLK_knockdown_48_GSE14525 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.54514 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A907-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lobules IV-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12069 Endometrial luminal epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.929 trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068288 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29E-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04133 Lung adenocarcinoma_LUAD_TCGA-44-4112-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-3026-SM-4B65M GTEx Tissue Sample Gene Expression Profiles 1.0 1.17994 GTEX-T5JC-0011-R4A-SM-32PLT GTEx Tissue Sample Gene Expression Profiles 1.0 0.999082 ES-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01761 Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hypothalamic medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31646 A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.34325 layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.22295 REST ENCODE Transcription Factor Targets 1.0 null GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03634 Usher syndrome type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.538 Whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GDI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65377 RBPJ ChEA Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178907_4_v_3_fkrp_human RummaGEO Gene Perturbation Signatures 1.0 null FBXO27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90672 Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null platelet GeneRIF Biological Term Annotations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.0565 BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3977 cervical cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.090755 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_12Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.34019 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06576 GTEX-S7PM-0126-SM-4AD6S GTEx Tissue Sample Gene Expression Profiles 1.0 0.847387 Thoracic aortic aneurysm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 Lung squamous cell carcinoma_LUSC_TCGA-22-0940-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parahippocampal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.83425 ELN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24352 GTEX-WL46-0011-R10A-SM-3MJFQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.81633 NCIH1568 CCLE Cell Line Gene CNV Profiles -1.0 -1.37492 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5538 hippocampus (hippocampal formation)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.86301 GTEX-S7SE-0011-R10A-SM-2XCDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.43718 decreased leukocyte cell number MPO Gene-Phenotype Associations 1.0 null PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null E2F7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88793 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null selectively GeneRIF Biological Term Annotations 1.0 null Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02626 others GeneRIF Biological Term Annotations 1.0 null 496100512_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02996 CML-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null TE4 CCLE Cell Line Gene CNV Profiles 1.0 1.42861 ERO1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35691 LU99 CCLE Cell Line Gene Expression Profiles -1.0 -1.70776 TCEA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37284 pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58007 anterior pretectal nucleus, dorsal core part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0335 c-Myc_OE_GDS3321_157_mouse_lung adenocarcinomas alveolar epithelia GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1746 GTEX-N7MT-0011-R10A-SM-2I3E1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2469 CTCF ENCODE Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36176 cellular_component GO Cellular Component Annotations 2015 1.0 null 496100324_FWM_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03673 AP3D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65996 A-CA-04-2009(H1N1)_7Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.29996 H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WVLH-3026-SM-3MJG9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.7687 STIMATE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97515 GSE186440,GSE186443_4_v_5_daxx_human RummaGEO Gene Perturbation Signatures -1.0 null GSU DepMap CRISPR Gene Dependency 1.0 5.31787 496100395_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.59347 MPRIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38063 Medial amygdalar nucleus, posterodorsal part, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0059 Cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 intermediate stratum of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22863 Interanteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14214 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.998673 MMRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40881 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.95512 Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RNOR-2326-SM-2TF4I GTEx Tissue Sample Gene Expression Profiles 1.0 1.43626 superficial stratum of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0009 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.12082 GTEX-PVOW-0011-R3A-SM-32PKX GTEx Tissue Sample Gene Expression Profiles 1.0 1.44618 GATA2_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cx40 GeneRIF Biological Term Annotations 1.0 null GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.908871 CTCF_GM12867_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE232564,GSE232566_0_v_2_nsd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86499 KON COSMIC Cell Line Gene Mutation Profiles 1.0 null FOS_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null increased circulating sodium level MGI Mouse Phenotype Associations 2023 1.0 null RBPJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73445 SNU503 DepMap CRISPR Gene Dependency 1.0 2.2696 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15543 inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26581 LXF289 CCLE Cell Line Gene Expression Profiles -1.0 -1.63156 H2AFZ ENCODE Transcription Factor Targets 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042114 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.005 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 mantle zone of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27046 Cardiomyocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.966 MGAT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65239 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.0164 Salivary duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.941 GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles 1.0 1.26969 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.8093 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.538 patterns GeneRIF Biological Term Annotations 1.0 null posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.991433 Fetal Death CTD Gene-Disease Associations 1.0 1.18093 GTEX-TSE9-0011-R8A-SM-3DB7R GTEx Tissue Sample Gene Expression Profiles 1.0 1.2331 PRPS1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39904 PC3 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Cardiac muscle cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.873 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89845 anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25435 SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.72899 Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A83M-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01094 ARL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05259 BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.391 GMEB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49397 Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM248 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23288 layer 3 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02191 Reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.05335 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17611 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-4J-AA1J-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ES-WA7 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.841219 NCIH292 DepMap CRISPR Gene Dependency 1.0 5.0158 DDX43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00817 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.596 CXXC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19571 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null NANOG-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38048 cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055678 Parabrachial nucleus, lateral division, dorsal lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10543 Pacemaker cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.789 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.966433 CBX8 ENCODE Transcription Factor Targets 1.0 null BL70 CCLE Cell Line Gene Expression Profiles 1.0 1.82897 GTEX-UTHO-0011-R3A-SM-3GIK8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.966004 Connexin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.266 SAP30 ENCODE Transcription Factor Targets 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949605 HR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80724 TTC442 DepMap CRISPR Gene Dependency 1.0 2.78704 HCC1395 CCLE Cell Line Gene CNV Profiles 1.0 1.51672 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null skeletal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.358919 Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36917 Connexin, N-terminal InterPro Predicted Protein Domain Annotations 1.0 null Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14545 GSE166004_7_v_0_pld1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0883 OVK18 DepMap CRISPR Gene Dependency 1.0 2.4581 Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QLQ7-1626-SM-2S1R8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.890712 Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4873 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 DDX31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36069 GTEX-REY6-2126-SM-48FD9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85957 SUMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46197 autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.245046 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0357 LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null limitans nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.887502 Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior frontal gyrus, right, medial bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.845112 Muscle tendon junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.036 hippocampus (hippocampal formation)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01487 Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS766T CCLE Cell Line Gene CNV Profiles -1.0 -1.80949 Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26204 dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.892737 protein complex GO Cellular Component Annotations 2015 1.0 null MOLT13 CCLE Cell Line Gene Expression Profiles -1.0 -2.27688 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2 Rummagene Transcription Factor Associations 2026 1.0 null SK-MEL-24 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13687 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77983 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36917 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null III, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.860114 transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.896885 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.964857 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D4-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gap junction assembly Reactome Pathways 2024 1.0 null Medial preoptic nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50098 JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Strabismic amblyopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.547 GTEX-Q2AG-0011-R10A-SM-2HMLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.67308 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.51861 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GATA3-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-P4PQ-0126-SM-2S1NM GTEx Tissue Sample Gene Expression Profiles 1.0 0.876231 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AP-1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-RWS6-1326-SM-47JXB GTEx Tissue Sample Gene Expression Profiles 1.0 0.962819 Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52756 COLO679 CCLE Cell Line Gene CNV Profiles -1.0 -1.53988 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal skeletal muscle morphology MPO Gene-Phenotype Associations 1.0 null Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Periventricular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45999 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052978 GOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18984 GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.06397 Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null peritoneal cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.400628 EM-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null SW403 DepMap CRISPR Gene Dependency 1.0 2.5798 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 BATF::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5327 PCI-30 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 KU1919 CCLE Cell Line Gene Expression Profiles -1.0 -1.51392 Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.005 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860226 Central medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1093 frontal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13805 Brain stem TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09613 GTEX-PLZ5-2026-SM-2S1O4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05463 SAT DepMap CRISPR Gene Dependency 1.0 4.00086 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11439 GSE193282_2_v_0_cd44_mouse RummaGEO Gene Perturbation Signatures -1.0 null Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30431 Uvula (IX), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05243 layer 4 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38088 JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0603 Rectum adenocarcinoma_READ_TCGA-F5-6571-01A-12R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.73398 OUMS23 CCLE Cell Line Gene CNV Profiles 1.0 2.02779 NMCG1 CCLE Cell Line Gene CNV Profiles -1.0 -1.73732 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3319 PARP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21377 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6178 GTEX-NPJ7-0011-R10A-SM-2I3E5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.5105 myoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.416576 CIT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03749 POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain GTEx Tissue Gene Expression Profiles 1.0 1.72027 layer 4 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01984 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 1.57576 OVOL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42741 LNX1 Pathway Commons Protein-Protein Interactions 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.854394 Sarcoma_SARC_TCGA-DX-A8BU-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.49089 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46707 Hippocampus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Medial preoptic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33732 GTEX-T2IS-0011-R2A-SM-32QPF GTEx Tissue Sample Gene Expression Profiles 1.0 1.15781 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100305_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.69054 short insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12317 GTEX-T6MO-1426-SM-4DM73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.857106 Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 33 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.022 GTEX-T5JW-2026-SM-4DM63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.991788 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 induced GeneRIF Biological Term Annotations 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.987348 layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26159 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052621 blastula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.239307 Retrochiasmatic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9074 GTEX-Q2AG-2926-SM-2HMJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56888 Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.25235 GSE164874_5_v_13_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null FBXL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03132 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QVUS-0011-R3A-SM-3GAFD GTEx Tissue Sample Gene Expression Profiles 1.0 1.13006 Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21559 Sarcoma_SARC_TCGA-FX-A3NK-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null middle frontal gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23726 macromolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.90502 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68962 CERS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20788 NCI-H2196 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67218 HIVEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33027 Lipopolysaccharides CTD Gene-Chemical Interactions 1.0 null Lobule II Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16463 Protein phosphatase inhibitor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.28 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68005 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059136 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.8815 SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051392 XBP1_OE_GDS5065_273_mouse_F424a adipocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.075 Proteinuria CTD Gene-Disease Associations 1.0 1.0894 MC116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32611 Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57464 alar plate of evaginated telencephalic vesicle Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30617 NCI-H2444 COSMIC Cell Line Gene Mutation Profiles 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-T6MN-0011-R8A-SM-32QP3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44147 TMEM191C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71508 periventricular stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03145 496100320_PCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.36133 retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.909986 Central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.893601 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51724 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0952 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.951518 EP300_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4425 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06943 ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5452 orbital frontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11782 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19934 PMC12179407-MCO2-6-e70261-s004.xlsx-down_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3 Rummagene Transcription Factor Associations 2026 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_7Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.44177 TE-10 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 AFDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46391 PANC0504 DepMap CRISPR Gene Dependency 1.0 7.26066 WM793 DepMap CRISPR Gene Dependency 1.0 2.0127 CHPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99921 Tetrachlorodibenzodioxin CTD Gene-Chemical Interactions 1.0 null GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.969284 Gap junction assembly Reactome Pathways 2014 1.0 null Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15167 Nucleus of the solitary tract, commissural part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48631 MCOLN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07621 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.982742 CARBENOXOLONE DGIdb Drug Targets 2026 1.0 0.508961 NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-WHSE-0011-R3A-SM-3P5ZM GTEx Tissue Sample Gene Expression Profiles 1.0 1.25616 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cell-cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 abnormal muscle regeneration MPO Gene-Phenotype Associations 1.0 null COLO679 DepMap CRISPR Gene Dependency 1.0 2.38305 GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 0.865381 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40092 PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23128 telencephalic vesicle Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30311 OB outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.08846 CEBPB ENCODE Transcription Factor Targets 1.0 null ZNF843 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1833 NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null KMRC1 DepMap CRISPR Gene Dependency 1.0 3.73321 Lobules IV-V, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15376 MTHFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89327 r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03145 Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41689 EJM DepMap CRISPR Gene Dependency 1.0 2.4477 TMEM167B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50386 layer 3 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46144 NCIH2110 CCLE Cell Line Gene CNV Profiles 1.0 1.73027 COLO205 CCLE Cell Line Gene Expression Profiles -1.0 -1.47243 autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.056103 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-2426-SM-3NMDB GTEx Tissue Sample Gene Expression Profiles 1.0 1.71466 CLPP_KO_GSE40207_399_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YI-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null alter GeneRIF Biological Term Annotations 1.0 null precentral gyrus, left, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.86635 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 0.926202 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33857 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053584 GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.960992 ARFGAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1525 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PDLIM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32466 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12109 Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 46.0372 GTEX-WWYW-3126-SM-3NB39 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41775 GTEX-OXRO-1726-SM-3LK6C GTEx Tissue Sample Gene Expression Profiles 1.0 0.834921 A-CA-04-2009(H1N1)_36Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.31322 Immune stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.0 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.833231 Feather bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.705 Stria vascularis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.006 ATM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67878 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053694 NCIH1693 DepMap CRISPR Gene Dependency 1.0 7.25941 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HSFY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84704 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Medial septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32471 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20623 ZNF20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7403 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.235457 AHSP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22147 ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1557 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8297 JM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.22359 CLPP_KO_GDS4791_376_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles 1.0 2.02714 Lung squamous cell carcinoma_LUSC_TCGA-43-8115-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 51.426 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9554 TMEM158 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01151 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 0.844371 RKO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03963 SETDB1 ENCODE Transcription Factor Targets 1.0 null hsa-miR-484 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 z chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.19468 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.49406 Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Fallopian Tube GTEx Tissue Gene Expression Profiles 2023 1.0 3.72861 ZNF341 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1593 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.08513 hsa-miR-4284 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GALNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82219 TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064824 CARF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47477 Slow muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.313 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE133070_3_v_1_prss1_mouse RummaGEO Gene Perturbation Signatures 1.0 null EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17469 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15856 Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62165 NCIH522 CCLE Cell Line Gene CNV Profiles -1.0 -1.6088 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.43567 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41643 Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.8407 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Umbilical vein endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.293 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ENDOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1668 anterodorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11119 UACC893 CCLE Cell Line Gene CNV Profiles 1.0 1.45461 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null inferior frontal gyrus, triangular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.60048 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 layer 2 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23128 H3K27me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles 1.0 1.09416 496100533_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04725 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05575 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1829 NCIH838 CCLE Cell Line Gene CNV Profiles -1.0 -1.61844 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040339 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lobules IV-V, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09287 LN18 CCLE Cell Line Gene CNV Profiles -1.0 -1.49574 Autosomal recessive nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.67 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54054 OB mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90293 CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LN340 CCLE Cell Line Gene CNV Profiles -1.0 -1.32769 LIMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27188