association	dataset	threshold value	standardized value
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11613
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.202
PDK1_knockout_80_GSE26290	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.211366
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96638
PPP1R15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37268
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88259
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870515
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0863
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5376
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45362
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8403
all	GWASdb SNP-Phenotype Associations	1.0	0.030595
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17008
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0512
MBD3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65319
TE441T	CCLE Cell Line Gene CNV Profiles	1.0	1.37124
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30406
ZBED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40533
lipid biosynthetic process	GO Biological Process Annotations 2025	1.0	null
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11217
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850837
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91657
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31773
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62564
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.8491
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52487
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59145
RKO	CCLE Cell Line Gene CNV Profiles	1.0	1.82331
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16331
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90051
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
T47D	DepMap CRISPR Gene Dependency	1.0	2.13562
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26241
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25506
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27239
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.953506
496100377_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.41963
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.83901
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53084
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899341
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.712131
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97547
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38436
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.92
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07509
Myelin membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30541
THAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6352
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
AP1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55878
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
SIRT4_KO_GDS4823_22_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33686
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.656
hsa-miR-23c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Ectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942173
tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.865912
C2BBE1	DepMap CRISPR Gene Dependency	1.0	5.28214
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.25
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08389
H3K9me3_U2OS_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.858917
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05979
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91122
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063918
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27996
Periodontal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.202
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29261
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00737
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.9168
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VIPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18466
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16333
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24479
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05788
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
COLO775	CCLE Cell Line Gene CNV Profiles	1.0	1.38204
SIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17141
chr9_135641276_C_T_b38	GTEx eQTL 2025	1.0	4.99236
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92025
SNU349	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61078
PANC0504	DepMap CRISPR Gene Dependency	1.0	3.72338
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40196
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0324
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.134
PMC11358472-41467_2024_51851_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_4_gene_expression_levels_for_323_genes_connected_to_EWS-WT1_in_JN-DSRCT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58449
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6835
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.50877
WM88	DepMap CRISPR Gene Dependency	1.0	5.54956
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16626
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06819
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
Gingival fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.324
hsa-miR-4647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4662a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79322
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.298
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04358
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2708
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.25
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41961
PEX26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5127
Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24594
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34667
496100288_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07253
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56237
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9232
APLN_KO_GDS3228_601_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29214
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03686
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.59038
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9286
layer 2 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19305
JUN	ENCODE Transcription Factor Targets	1.0	null
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4521
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82367
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3611
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87483
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
ADPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68432
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17008
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.842352
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89393
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.635
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
C8orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21794
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
PKP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85391
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24084
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72501
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00917
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.51418
Dental plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20843
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.80925
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
MKN45	CCLE Cell Line Gene CNV Profiles	1.0	1.33927
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23465
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8031
HNRNPA0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79512
abnormality of the oral cavity	GWASdb SNP-Phenotype Associations	1.0	0.246718
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48102
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56659
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39338
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889107
MUTYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57891
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826323
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1147
Gingivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31354
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17321
SARS-CoV MA15_Day4-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.55727
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53326
ZNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33804
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99977
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13149
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2446
mantle zone of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11667
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2294
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15751
CCDC120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76423
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944711
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44938
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15174
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30426
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980283
hsa-miR-494	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45021
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
496100591_TCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.64012
Lactose	DrugBank Drug Targets	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.90529
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
CUX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68696
TRIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92384
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7706
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2723
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8198
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.638
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3909
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42833
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4577
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24711
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALS2CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77012
CDYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05073
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50243
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30907
hsa-miR-376c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1674
Brain Lower Grade Glioma_LGG_TCGA-DB-A64U-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90457
TMEM191C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71508
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61466
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
GNAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4069
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057483
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91046
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57163
Brain Lower Grade Glioma_LGG_TCGA-P5-A5ET-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889107
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25886
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.63638
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SOX2	ChEA Transcription Factor Targets	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.849
GSE129241_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42096
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56392
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01193
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
MTERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07512
Ebolavirus(ZEBOV)_1day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69097
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98267
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09631
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
lm8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Mouth disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.202
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40986
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06842
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826323
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06102
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
PFSK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF417	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95296
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4738-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12404
TKKK	DepMap CRISPR Gene Dependency	1.0	9.47977
SYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9831
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
PYGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20974
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49718
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.873
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FUCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75458
C1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1182
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5738
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
NT5C3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95497
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07802
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61296
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06884
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16279
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03898
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05614
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05618
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11667
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08949
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66443
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0948
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45211
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00737
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45362
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.04909
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.4347
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
periodontal disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.552621
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87724
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59389
SNUC5	DepMap CRISPR Gene Dependency	1.0	2.12049
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15508
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13165
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37284
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14127
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990808
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0499
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10403
Reticulum trabeculare	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
RHJT	DepMap CRISPR Gene Dependency	1.0	2.25161
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48798
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63645
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02414
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.485
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49085
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2702
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94833
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826323
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30545
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42467
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12002
lipid modification	GO Biological Process Annotations 2025	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37191
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.5401
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.631
JVE015	DepMap CRISPR Gene Dependency	1.0	2.43315
Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4581
Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10601
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.369
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65677
CLDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18135
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27023
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80225
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83252
SKMEL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52956
DNA recombinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8328
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22646
SLC41A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33273
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33131
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.922894
adult testis	HPM Cell Type and Tissue Protein Expression Profiles	1.0	0.824335
496100528_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47004
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.3032
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68392
EZH2	ENCODE Transcription Factor Targets	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0656
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08337
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9994
SLC6A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44948
ZFX_KO_GDS2718_151_mouse_hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13659
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.553
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-0.771889
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
496100432_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.11224
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19873
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43805
mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.825768
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LIFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15994
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67991
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8427
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99827
NKX3-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25469
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02011
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24063
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	2.23047
vesicle	GO Cellular Component Annotations 2023	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11154
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13701
SLC2A4	Hub Proteins Protein-Protein Interactions	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11199
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9212
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17104
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31213
superficial stratum of PaS (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15863
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31922
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74362
CORL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53722
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.98887
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80048
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6871
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31512
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	1.35475
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0892
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850837
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23399
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
TBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46002
496100638_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.17375
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57806
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85171
Periodontitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.654
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74611
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79085
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49129
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52343
RASSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17322
MDAMB361	DepMap CRISPR Gene Dependency	1.0	5.28012
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4314
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19008
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.174
colo829	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.398
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5175
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42719
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8967
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5948
RAB3A_KO_GDS2483_700_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76867
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78M-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0258
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.145225
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45414
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79642
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.919945
RASSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75948
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	5.71911
Aggressive Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
PPARGC1A_KO_GDS2391_299_mouse_brain striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93873
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054777
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.552621
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07912
SW403	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8973
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9076
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43888
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963301
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.638
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.027953
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03304
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60282
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33725
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31922
Dental caries	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.33933
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60386
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24113
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.202
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71391
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056455
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	2.54856
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92231
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
PCDH12_Deficiency_GDS3415_577_mouse_Embryonic placentas (12.5 day)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65392
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43297
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21288
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0026
mantle zone of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03304
ANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9594
TPST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56041
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77188
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6316
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41251
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963301
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
MRPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52868
MDAMB415	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41322
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08337
BMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44319
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09209
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75291
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
Oral epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40971
ZNF525	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5036
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27239
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08949
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00537
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3428
FAM43B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.451
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6945
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19588
SLC29A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38643
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11997
hsa-miR-4760-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16066
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15863
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.712526
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31126
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871655
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
KIF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45437
periodontitis	GAD Gene-Disease Associations	1.0	null
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66661
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902311
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	2.28863
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
layer 6 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13738
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4119
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
PA-TU-8902	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.858917
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21326
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48528
CYP2U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05524
GTF3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46756
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.4984
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8291
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59313
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.06355
hsa-miR-136	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76924
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1599
LAPTM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57302
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62813
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H357	DepMap CRISPR Gene Dependency	1.0	4.04143
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44222
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57896
mouth disease	GWASdb SNP-Disease Associations	1.0	0.408021
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.72388
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05304
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2065
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PA1	DepMap CRISPR Gene Dependency	1.0	2.24466
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26716
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.16
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08302
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15751
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
Gata-4_KO_GDS4782_329_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16973
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHOP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
MTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81502
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00846
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15863
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15223
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14144
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RQ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2453
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0245
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
JEG3	DepMap CRISPR Gene Dependency	1.0	3.14128
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.782
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.577
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92226
ERBB2_knockdown_232_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.85809
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32989
SNRK_overexpression_127_GSE30185	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.47446
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7169
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0255
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02759
TGFBR3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85664
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88194
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01372
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
periodontitis	GeneRIF Biological Term Annotations	1.0	null
KP2	DepMap CRISPR Gene Dependency	1.0	3.55509
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10643
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87314
srf_20709909_hematopoietic_stem_cell_lof_mouse_gpl1261_gds3732	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.057479
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31922
HCC1187	DepMap CRISPR Gene Dependency	1.0	5.39792
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SRGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69983
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
aggressive periodontitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.51853
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053661
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26999
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77792
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61897
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6968
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAVER1	DepMap CRISPR Gene Dependency	1.0	3.36343
ARRDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7842
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2348
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4159
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85287
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82426
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
TERF2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61352
hsa-miR-4533	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02148
OVMIU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31922
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61111
Alveolar bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.567
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83516
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.17257
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40166
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16462
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8697
CPNE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60217
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00846
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80048
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47334
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9306
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.6528
SIRT4_KO_GDS4823_505_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07287
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2977
periodontitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.99908
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35409
SIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48475
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89615
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00657
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65029
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26995
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16158
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53761
GOS3	CCLE Cell Line Gene CNV Profiles	1.0	1.64368
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75585
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7787
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.771889
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.7955
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18694
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25077
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0763
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Teeth hard tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
SOX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27088
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28736
hsa-miR-4646-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19469
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82697
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19453
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00537
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16502
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05241
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46491
YD38	CCLE Cell Line Gene CNV Profiles	1.0	1.48805
hsa-miR-4426	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
KP-N-RT-BM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-Genes_with_ATF3_combined_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963301
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
SMARCAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66854
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49639
BICR22	CCLE Cell Line Gene CNV Profiles	1.0	1.40689
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22295
GATA1	ENCODE Transcription Factor Targets	1.0	null
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59963
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29676
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19305
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V6-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54262
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
molecular_function	GO Molecular Function Annotations 2015	1.0	null
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11139
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6787
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052507
BSX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96136
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
ISX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55328
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
TRIM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45218
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HECA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26637
SLAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4877
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17626
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4899
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1445
tooth disease	GWASdb SNP-Disease Associations	1.0	0.44312
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5323-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6116
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8352
Gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.917
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30845
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95184
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0871
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53148
hsa-miR-4799-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Uridine-5'-Monophosphate Glucopyranosyl-Monophosphateester	DrugBank Drug Targets	1.0	null
ERBB2_knockdown_238_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.75726
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0952
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79003
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
PVR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6928
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56784
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02759
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6395
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45373
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.779962
GNG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20211
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42467
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
LTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38235
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Odontoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06781
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0695
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52129
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81411
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10018
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5504
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93582
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60827
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13113
biological_process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RABEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98313
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81596
PABPC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29408
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.13275
Lung adenocarcinoma_LUAD_TCGA-44-2655-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914455
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11154
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40997
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20681
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30474
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5418
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09242
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051675
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051675
Warburg micro syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81734
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3148
SOX9	ChEA Transcription Factor Targets	1.0	null
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28828
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8615
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98643
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28552
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SIRT4_KO_GSE56321_391_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66715
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Proteasome storage granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
NR2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13236
hsa-miR-4314	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
alveolar bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.651371
SCLY	ChEA Transcription Factor Targets	1.0	null
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.900656
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30117
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28462
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15143
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.5401
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RP-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23243
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02553
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76656
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052041
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3
Uridine-5'-Monophosphate	DrugBank Drug Targets	1.0	null
horsetail-astral microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
FADU	CCLE Cell Line Gene CNV Profiles	1.0	1.86469
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01805
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62131
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7631
ARHGAP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27902
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5854
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52951
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	0.858917
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SARM_KO_GDS4842_412_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16195
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30034
bone marrow	HPA Tissue Protein Expression Profiles	1.0	0.858917
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43724
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40181
Periodontal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56446
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37062
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84758
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.91
JVM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.989016
RIOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78931
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42463
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.033302
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80728
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7504
Acute Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T2-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1934
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29155
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15542
Buccal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
RDES	DepMap CRISPR Gene Dependency	1.0	3.49276
PMC11956947-media-4.xlsx-C_GSEA_gene_sets-TGAYRTCA_ATF3_Q6_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.369
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040546
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00216
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
CAPAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19292
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57997
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4720-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58101
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31922
L1236	DepMap CRISPR Gene Dependency	1.0	2.79305
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80048
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54147
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988192
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2767
SR786	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13228
abnormality of the face	GWASdb SNP-Phenotype Associations	1.0	0.189142
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.518
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059765
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6464
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71292
HCC1419	CCLE Cell Line Gene CNV Profiles	1.0	1.48869
TE9	DepMap CRISPR Gene Dependency	1.0	2.93986
RAB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89972
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35068
Aggressive periodontitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.009
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45821
Glycosyl transferase, family 6	InterPro Predicted Protein Domain Annotations	1.0	null
BC3C	DepMap CRISPR Gene Dependency	1.0	2.32945
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39129
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
Brain Lower Grade Glioma_LGG_TCGA-HT-7483-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9163
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.76121
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11613
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.62764
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0276
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46695
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0027
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37284
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44561
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31773
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75645
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25886
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
PROKR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72705
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.49257
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.832556
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15508
carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49747
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11328671-jitc-12-4-s003.pdf-126-GLI4_GLI4	Rummagene Transcription Factor Associations 2026	1.0	null
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9015
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07469
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.8163
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80013
MFSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49941
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15505
DU4475	DepMap CRISPR Gene Dependency	1.0	6.6562
hsa-miR-1298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.1294
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41712
lipid glycosylation	GO Biological Process Annotations 2025	1.0	null
ING2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35527
PLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86122
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57714
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00846
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61965
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47456
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848198
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63428
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7167
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3695
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23198
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5653
SERPINB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19324
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09337
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03304
Biofilm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03304
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77652
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80048
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35845
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95531
hsa-miR-23b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2696
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57631
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.858917
FOXO1_KD_GDS2720_478_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PECAPJ15	DepMap CRISPR Gene Dependency	1.0	2.48854
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47068
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6909
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38513
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46728
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01107
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37469
Molaris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
H3K9me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.95646
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053523
KMM1	DepMap CRISPR Gene Dependency	1.0	2.25703
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11141
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826323
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.596
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.69886
THAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54927
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37284
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70566
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68253
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940411
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.2367
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48332
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0695
Periodontosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06274
Papillon-Lefevre disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74546
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6871
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-924	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30664
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46573
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889107
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01686
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.919945
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00198
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01841
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08039
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32466
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.5937
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28464
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	2.81635
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7804
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	4.22126
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.62734
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940411
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.969
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59431
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10149
KDM6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73208
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	2.16109
Smc5-Smc6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.841
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11931
ANKRD65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91072
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7517
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16852
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93459
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7077
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055433
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RLIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98686
isthmus proper	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11667
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8471
RH18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79545
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49644
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50086
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	3.23847
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58828
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25098
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04665
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907789
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054137
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.38354
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23188
DBNDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31585
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68263
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5403
ZC3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
HOXB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74055
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02628
ETF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.85405
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36302
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042491
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22434
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9657
BL1165 (TRIM24)	NURSA Protein Complexes	1.0	null
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38888
SRY	ChEA Transcription Factor Targets	1.0	null
periodontitis	GWASdb SNP-Phenotype Associations	1.0	1.27347
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31922
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00737
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92667
hsa-miR-664	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KYSE30	DepMap CRISPR Gene Dependency	1.0	3.30923
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9454
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04806
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21794
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06067
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45735
YRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33436
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02221
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.309
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76036
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
VBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55819
OVTOKO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4751
TNRC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22434
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15863
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82647
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45181
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16343
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93207
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.27128
PDIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4079
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69059
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53088
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94175
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0695
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31773
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EA-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80048
RAB3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43274
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69759
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03304
Periodontal ligament cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.608
SKHEP1	DepMap CRISPR Gene Dependency	1.0	2.78008
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63587
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053672
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051497
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-493	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2711
hsa-miR-3121-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41114
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06306
L3MBTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78113
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12681
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.03064
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51274
hsa-miR-323-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Uridine-5'-Diphosphate	DrugBank Drug Targets	1.0	null
RCM1	DepMap CRISPR Gene Dependency	1.0	6.83661
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.794
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00678
KRAP_Deficiency_GDS3528_564_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
PSS008	DepMap CRISPR Gene Dependency	1.0	2.08682
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3748
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975551
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4028
membrane part	GO Cellular Component Annotations 2015	1.0	null
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10364
PICALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71893
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
CORL311	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45844
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7665
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05287
EIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.52214
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09863
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periodontosis	DisGeNET Gene-Disease Associations	1.0	null
MCAD_KO_GDS4546_423_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7026
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29913
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87613
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.56395
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0085
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11106
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8377
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
abnormality of oral mucosa	GWASdb SNP-Phenotype Associations	1.0	0.60335
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7764
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RECQL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55327
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45211
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.51512
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66067
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4996
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22167
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053988
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04939
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7474-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24846
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11667
ZNF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54565
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
B3GNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59135
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92727
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41881
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.88167
Midbrain reticular nucleus, retrorubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00537
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00122
FBXO34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85773
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15508
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4783
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17008
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43058
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1315
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5292
Nucleotide-diphospho-sugar transferases	InterPro Predicted Protein Domain Annotations	1.0	null
Juvenile glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
DBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34007
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60769
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57976
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6408
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.38186
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3525
Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-606	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20911
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5816
ADCYAP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16251
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.638
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30297
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2857
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45469
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.771889
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.50971
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50275
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05451
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05614
SLC25A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58921
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15489
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100627_TCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.21685
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56578
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.39173
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SW626	DepMap CRISPR Gene Dependency	1.0	2.79155
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-23a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7133
SLC29A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49876
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27239
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38115
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93207
TWF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50391
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89823
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
PCGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17008
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04297
c-Myc_OE_GDS3321_157_mouse_lung adenocarcinomas alveolar epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07623
hsa-miR-4729	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.605
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5215
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15285
hsa-miR-3143	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48202
NB7	DepMap CRISPR Gene Dependency	1.0	3.84055
BHT101	DepMap CRISPR Gene Dependency	1.0	5.09158
FOXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74386
periodontal disease	GWASdb SNP-Disease Associations	1.0	1.4479
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98554
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.388
PLIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57754
hsa-miR-297	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
WARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03859
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853463
Brain Lower Grade Glioma_LGG_TCGA-DB-A64L-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TEAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17686
ANKRD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45092
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.638
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.575
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8284
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.91888
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5362
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42291
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940411
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2619
Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34936
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855064
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9373
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.0178
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66456
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-1.10719
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60787
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32574
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03173
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29165
BMPR1A_knockout_222_GSE48092	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.929394
NARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23457
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37191
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43065
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832493
Gingival fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.688
PMC10709143-41556_2023_1271_MOESM10_ESM.xls-Up_hPSC_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
HOUAI	DepMap CRISPR Gene Dependency	1.0	2.132
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2725
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94833
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9101
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22942
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16061
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2476
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3227
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05788
hsa-miR-1265	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
periodontitis	GWASdb SNP-Disease Associations	1.0	1.4479
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76179
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84679
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
CLDN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57434
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
VIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.40451
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7832
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.942
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65147
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8795
HSFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21444
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.2106
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6858
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69059
SEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11401
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45362
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4996
DPPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40681
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05721
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2857
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48521
VPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54107
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
A-VN-1203-2004(H5N1)_Day4-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73501
IRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41346
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36761
Oral epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6466
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962069
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12681
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63587
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15751
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957701
ABCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12008
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43398
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vagina	HPA Tissue Protein Expression Profiles	1.0	0.858917
BB30HNC	DepMap CRISPR Gene Dependency	1.0	4.78647
Cortical microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81535
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.921978
Warburg micro syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258917
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83291
POLR2A	ENCODE Transcription Factor Targets	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7927
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56725
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.552621
abnormality of the head	GWASdb SNP-Phenotype Associations	1.0	0.163421
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38826
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03083
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65895
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16763
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53303
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16191
Buccal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5561-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90527
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99516
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2047
transferase activity, transferring hexosyl groups	GO Molecular Function Annotations 2015	1.0	null
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
NCIH1793	CCLE Cell Line Gene CNV Profiles	1.0	1.33053
Tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.808
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57214
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3554
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18089
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33457
LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060748
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87788
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47563
Buccal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61962
ELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10673
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8427
DDX19A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81524
Lemierre's syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833976
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38748
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2098
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20506
L363	DepMap CRISPR Gene Dependency	1.0	2.21794
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.976
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21794
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42631
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92955
MOLM6	CCLE Cell Line Gene CNV Profiles	1.0	2.03652
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35612
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40962
CASKIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69487
Brain Lower Grade Glioma_LGG_TCGA-E1-5307-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890854
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.61078
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40322
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98876
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31922
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.98424
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9172
TBXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88041
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49966
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43109
abnormality of the teeth	GWASdb SNP-Phenotype Associations	1.0	0.277509
hsa-miR-892a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.638
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00846
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24473
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9786
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.5197
reproductive system phenotype	MGI Mouse Phenotype Associations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.56814
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5441-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4409
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2896
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_TGAYRTCA_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05069
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6659
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9081
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61648
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27957
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.97594
GSE213410_0_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34266
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10092
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08107
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23188
NCIH2030	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83455
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25096
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04358
Cementum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-1.5401
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44095
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90131
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11613
LXF289	CCLE Cell Line Gene CNV Profiles	1.0	1.52235
HSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25904
rectum	HPA Tissue Protein Expression Profiles	1.0	0.858917
locus	GeneRIF Biological Term Annotations	1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5454
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42918
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32535
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26806
PLAGL2_deficiency_GDS3010_139_mouse_embryonic small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1625
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57152
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XC-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2228	COSMIC Cell Line Gene Mutation Profiles	1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	0.858917
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of head or neck	GWASdb SNP-Phenotype Associations	1.0	0.163421
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.60539
IL17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8375
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29435
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26592
ZFP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90916
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2986
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87483
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32345
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07287
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68224
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95741
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4646
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20506
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9853
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
ATL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41825
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217554
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
transferase activity, transferring glycosyl groups	GO Molecular Function Annotations 2015	1.0	null
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05614
Gingival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12232
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06797
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28967
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.813573
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7709
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54633
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
p1 part of the substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01841
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8863
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83033
496100521_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.83206
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23119
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7083
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8906
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05831
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9987
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96493
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.782
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.324094
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76628
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.858917
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16783
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55736
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.726
LYPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06926
Subceruleus nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00989
susceptibility	GeneRIF Biological Term Annotations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40183
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45362
layer 2 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27239
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2239
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54043
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26716
FIGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36137
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43499
GGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13938
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01562
Prostate adenocarcinoma_PRAD_TCGA-HC-8216-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.64034
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94004
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57861
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6701
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33291
GAS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99003
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22501
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41358
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4634
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.54495
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54803
PMC10863107-12977_2024_635_MOESM8_ESM.pdf-6-ZFP37_ZFP37	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
Periodontitis	dbGAP Gene-Trait Associations	1.0	0.788408
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-1.5401
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
SIRT4_KO_GDS4823_30_mouse_hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Periodontitis	GWAS Catalog SNP-Phenotype Associations	1.0	0.455873
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20489
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11461
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3529
abnormality of the mouth	GWASdb SNP-Phenotype Associations	1.0	0.234311
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.858917
hsa-miR-4693-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1941
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97193
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41803
Beta-D-Glucose	DrugBank Drug Targets	1.0	null
tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.370496
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9313
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76366
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57375
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7397
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58068
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910308
GNAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50973
PDE7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91809
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02596
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41114
Aggressive Periodontitis	HuGE Navigator Gene-Phenotype Associations	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
G402	DepMap CRISPR Gene Dependency	1.0	3.32504
IRX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09264
CCZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74446
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35893
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF483	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16355
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83925
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989079
Cervical adenosquamous carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.01102
GF-57-MY04_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.525879
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3506
496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09473
JHU011	DepMap CRISPR Gene Dependency	1.0	2.03288
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9615
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15734
Incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93207
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1905
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52137
ERRFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33874
periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.537416
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.888553
hsa-miR-499-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.870192
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21399
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3075
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98075
hsa-miR-765	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
vesicle	GO Cellular Component Annotations 2025	1.0	null
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17322
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6872
Periodontitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30176
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4563
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.2506
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37814
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93881
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93582
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30409
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
parasubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15863
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20421
tooth disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.552621
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2006
GDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65377
FLI1	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5349
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94833
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15058
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72787
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16258
abnormality of the gingiva	GWASdb SNP-Phenotype Associations	1.0	0.60335
hsa-miR-617	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4011
SKRC31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74027
RUNX1_KO_GDS1511_250_mouse_Embryos at E8.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
UHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28941
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01193
Presubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04066
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98768
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19146
MORF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34164
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1908
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.833018
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60978
gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.552621
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1086
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05788
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29119
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
METTL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.162
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	3.26834
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
TCEA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2598
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70334
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02553
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3521
ZNF184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21935
PMC7068927-12885_2020_6709_MOESM1_ESM.docx-1-GFI1_GFI1	Rummagene Transcription Factor Associations 2026	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40257
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0324
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64039
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18089
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13599
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43297
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08928
AATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51002
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13088
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.202
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.72615
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61347
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2928
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43125
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.50215
PEO4	DepMap CRISPR Gene Dependency	1.0	4.21468
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2497
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20573
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7422-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57442
ZNF747	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01487
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85308
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64978
HAGHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48327
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71039
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93873
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61215
metabolic process	GO Biological Process Annotations 2015	1.0	null
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36757
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6608
hsa-miR-4662b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60777
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82467
NOMO1	DepMap CRISPR Gene Dependency	1.0	3.00505
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SARS-CoV MA15_Day4-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.23184
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.638
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873305
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25874
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ES-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.334
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13738
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
SU-DHL-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17733
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
HCC2998	DepMap CRISPR Gene Dependency	1.0	3.3137
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
KRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06462
Periodontitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.202
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C10	DepMap CRISPR Gene Dependency	1.0	6.07993
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7388
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4812
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8844
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31773
hsa-miR-3618	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.32
brain	GTEx Tissue Gene Expression Profiles	1.0	0.934025
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15091
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39014
mouth disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.552621
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85153
MAFK	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09188
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.37261
hsa-miR-501-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1057
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2063
SIX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98198
mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439123
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7643
ESR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68699
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94386
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22654
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22166
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63499
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8319
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09257
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15397
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
testis	HPA Tissue Protein Expression Profiles	-1.0	-0.771889
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46968
VCY1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40782
periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.918024
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981681
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7480-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36777
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50006
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.882917
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.638
Brain Lower Grade Glioma_LGG_TCGA-FG-8191-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW8	DepMap CRISPR Gene Dependency	1.0	2.7705
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04139
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74118
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9768
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2555
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3066
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874363
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.2085
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04898
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90182
ARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26561
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14004
mantle zone of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15863
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05109
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68098
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
PECAPJ15	CCLE Cell Line Gene CNV Profiles	1.0	2.59412
Gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23188
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02148
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53326
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11228
SERPINB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98646
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05287
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9518
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4014
MEGF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74536
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63071
SW1116	CCLE Cell Line Gene CNV Profiles	1.0	2.13286
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13738
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
SLC39A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34239
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93207
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933315
skin	GTEx Tissue Gene Expression Profiles	1.0	1.17765
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.62719
NBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36612
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67499
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
layer 5 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18089
hsa-miR-31	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826323
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30567
CEND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14428