association	dataset	threshold value	standardized value
3Z-dodecenoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
vagina	HPA Tissue Protein Expression Profiles	1.0	1.17234
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77081
bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38222
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966493
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833421
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GW-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3609	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
monounsaturated fatty acid catabolic process	GO Biological Process Annotations 2025	1.0	null
chr11_58948296_T_C_b38	GTEx eQTL 2025	1.0	1.43775
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
F5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00146
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
Palmityl-CoA	HMDB Metabolites of Enzymes	1.0	null
Salivary_Gland-duct epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	2.35234
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glycines	GeneRIF Biological Term Annotations	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87933
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040579
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2891-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973934
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42C-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11423
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.973306
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09021
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81742
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	2.05065
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04718
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
glycine n-acyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0852
496100663_TCx_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4273
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063427
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NR1H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21847
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.148063
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952163
TE441T	CCLE Cell Line Gene Expression Profiles	1.0	1.59931
Glutarylglycine	HMDB Metabolites of Enzymes	1.0	null
Trachea-serous cell of epithelium of trachea	Tabula Sapiens Gene-Cell Associations	1.0	2.33548
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862409
lysines	GeneRIF Biological Term Annotations	1.0	null
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)	Reactome Pathways 2014	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10823279-CAS-115-283-s001.xlsx-Table_S6-Table_S6_List_of_182_genes_particularly_down-regulated_by_AR_in_AILNCaP14_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9046280-41467_2022_29963_MOESM8_ESM.xlsx-Supplementary_Fig_4B-Genes_annotated_to_enhancers_bound_by_ASCL1_ChIP_and_lost_expression_in_42D_K_D_ASCL1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07779
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22136
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70057
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40248
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87717
SCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35061
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24351
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03507
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59909
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.94249
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thus	GeneRIF Biological Term Annotations	1.0	null
Propionylglycine	HMDB Metabolites of Enzymes	1.0	null
Acetyl-CoA	HMDB Metabolites of Enzymes	1.0	null
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921177
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	3.66485
BAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40442
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82172
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860735
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932065
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934491
synthesizes	GeneRIF Biological Term Annotations	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901158
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14787
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.313552
SUDHL5	DepMap CRISPR Gene Dependency	1.0	12.3923
NPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50886
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94332
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10446
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60527
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824311
HS611T	CCLE Cell Line Gene Expression Profiles	1.0	1.61165
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22701
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25865
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	1.46266
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5527
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53447
RERFLCAD2	CCLE Cell Line Gene Mutation Profiles	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.17234
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)	Reactome Pathways 2014	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1458
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056413
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB468	CCLE Cell Line Gene Expression Profiles	1.0	1.93052
MEG-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60803
SUDHL10	CCLE Cell Line Gene Mutation Profiles	1.0	null
Glycine N-acyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC2157	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
Ewing's sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SARS-BatSRBD_12Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.63349
LNZ308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43416
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, frontal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.835699
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0406
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22135
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.23535
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09506
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCL22	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80053
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056418
EW-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Heptanoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11385
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885708
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3349-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2113	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16943
Isobutyryl-CoA	HMDB Metabolites of Enzymes	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885036
BT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28943
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868597
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96908
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDC7_knockdown_109_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.99841
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901158
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04546
Drug ADME	Reactome Pathways 2024	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01088
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50712
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.164
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89391
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32363
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.97285
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68936
N-Acetyl-L-methionine	HMDB Metabolites of Enzymes	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSC19	DepMap CRISPR Gene Dependency	1.0	2.01882
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28451
CDC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51677
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993266
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.83505
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51125
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X15G-1626-SM-3NMB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68174
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04033
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864825
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40778
Perturb_6697_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.25267
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74904
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1988
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02899
LS123	DepMap CRISPR Gene Dependency	1.0	6.47586
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Survivin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5516
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.73755
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30606
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37596
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0238
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058291
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32116
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40328
HCC1954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862409
Aspirin ADME	Reactome Pathways 2024	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5049
SNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15757
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87943
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.336144
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM229PE	DepMap CRISPR Gene Dependency	1.0	2.71971
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56177
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858744
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2106	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51519
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-UJHI-1426-SM-3DB9C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3918
cellular_component	GO Cellular Component Annotations 2015	1.0	null
long-chain fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
Metapathway biotransformation(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Suberylglycine	HMDB Metabolites of Enzymes	1.0	null
LOUCY	CCLE Cell Line Gene Expression Profiles	1.0	2.26586
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984633
DOHH2	CCLE Cell Line Gene Expression Profiles	1.0	1.51752
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3352
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1795
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC9117466-NIHMS1784916-supplement-Supplementary_Tables_1_to_7.xlsx-Table_3-Supplementary_Table_3_HOXB13-repressed_genes_that_were_or_were_not_rescued_by_G84E_in_Fig_1a_HOXB13	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3692
calcitriol_homo sapiens_gpl570_gse35925	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
N-Acetylleucine	HMDB Metabolites of Enzymes	1.0	null
NCIH2405	CCLE Cell Line Gene Mutation Profiles	1.0	null
Perturb_6688_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.88244
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3367-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863728
GTEX-XUW1-2326-SM-4BOO5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11751
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926281
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87633
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.18372
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40432
IM95	DepMap CRISPR Gene Dependency	1.0	5.32348
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12989
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890332
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37596
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1491
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE160817_4_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871952
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.569645
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06105
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09031
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84443
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984818
NCIH520	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892761
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96519
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57044
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861081
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866048
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918104
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0139
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03931
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52177
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X0-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5048
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993269
MED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10769
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8278-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.17234
acetylation	GeneRIF Biological Term Annotations	1.0	null
Perturb_980_OE_NANOGP8_SRP065951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.28941
Amino Acid conjugation	Reactome Pathways 2024	1.0	null
SF126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	4.62183
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.61966
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34752
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.55681
19962670-TableS2	GeneSigDB Published Gene Signatures	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Metapathway biotransformation Phase I and II	WikiPathways Pathways 2024	1.0	null
glycine N-acyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
HS675T	CCLE Cell Line Gene Mutation Profiles	1.0	null
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876418
UACC893	CCLE Cell Line Gene Expression Profiles	1.0	1.94447
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.543
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09829
transferase activity, transferring acyl groups other than amino-acyl groups	GO Molecular Function Annotations 2015	1.0	null
H3K9me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
salivary gland	HPA Tissue Gene Expression Profiles	1.0	1.3581
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32102
Lung-respiratory goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	1.32384
SKLU1	CCLE Cell Line Gene Mutation Profiles	1.0	null
2-Methylbutyryl-CoA	HMDB Metabolites of Enzymes	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03615
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01377
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05163
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.3483
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00659
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957164
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70726
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895764
Perturb_17331_KD_PUM1_SRP170955	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.3687
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3009
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3901
RDH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49862
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93892
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.36467
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87119
biological	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4852-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88701
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31482
SKN3	DepMap CRISPR Gene Dependency	1.0	2.86254
Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integrin alphav-beta8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10635
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08722
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3675
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glycine	DrugBank Drug Targets	1.0	null
HCC1569	CCLE Cell Line Gene Expression Profiles	1.0	3.40781
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00547
FLI1	ChEA Transcription Factor Targets	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052944
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.42598
GSE164726_0_v_1_phf10_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01542
Trachea-secretory cell	Tabula Sapiens Gene-Cell Associations	1.0	0.295345
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1914
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TLDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46236
Orotic aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26955
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
N-[(3a,5b,7a,12a)-3,12-dihydroxy-24-oxo-7-(sulfooxy)cholan-24-yl]-Glycine	HMDB Metabolites of Enzymes	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.81521
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62174
COLO829	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45431
PMC11098130-pnas.2322688121.sd02.xlsx-NER_Contact_vs_mono-id_NR1H2	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	Reactome Pathways 2014	1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09503
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37581
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11092
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08504
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06428
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847363
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3592-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crotonoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893018
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39227
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nacyl	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-LI-A9QH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6241
NOL4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10525
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856063
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-3.27139
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.89519
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
Breast hyperplasia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57284
Lung adenocarcinoma_LUAD_TCGA-86-8074-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40591
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0896
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87798
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44759
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64481
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13828
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18029
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88892
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21828
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6974
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922998
PTEN_01_218	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.09051
glycine	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869493
Acute Myeloid Leukemia_LAML_TCGA-AB-3000-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSTO211H	DepMap CRISPR Gene Dependency	1.0	4.26546
GTEX-QCQG-1226-SM-48U23	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00196
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2743
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
N-Heptanoylglycine	HMDB Metabolites of Enzymes	1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0125
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amino acid conjugation of benzoic acid	WikiPathways Pathways 2024	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37483
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52224
MOLT13	CCLE Cell Line Gene Expression Profiles	1.0	1.79109
RT112	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8165
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.46264
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28688
NALM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63497
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9016
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38002
hsa-miR-654-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
molecules	GeneRIF Biological Term Annotations	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6446
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40599
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Rectum adenocarcinoma_READ_TCGA-CI-6623-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	CCLE Cell Line Gene Expression Profiles	1.0	2.15504
3-Methylcrotonylglycine	HMDB Metabolites of Enzymes	1.0	null
estradiol_homo sapiens_gpl14550_gse35034	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882889
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8121
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83497
HSC3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44241
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GO-06A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863223
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05171
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	1.0	1.51447
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12897
Lung adenocarcinoma_LUAD_TCGA-93-7348-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4786-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06423
IPC298	DepMap CRISPR Gene Dependency	1.0	2.03297
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2924
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5098
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECC12	CCLE Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16711
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hydroxyphenylacetylglycine	HMDB Metabolites of Enzymes	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27599
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45489
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7476
MEWO	CCLE Cell Line Gene Mutation Profiles	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910794
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.70854
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81032
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0026
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916148
GSE133927_1_v_3_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07042
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65922
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metabolism	Reactome Pathways 2024	1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952262
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
paracentral lobule, anterior part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.953189
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862409
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33233
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923132
CREBBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4QS-0626-SM-3NMD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06417
modification	GeneRIF Biological Term Annotations	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.09733
PCNA-p21 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.313
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040193
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67115
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864609
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22853
NB6	DepMap CRISPR Gene Dependency	1.0	3.41508
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15621
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01432
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832639
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21756
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18824
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944812
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36836
Octanoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
NCIH1666	CCLE Cell Line Gene Mutation Profiles	1.0	null
ZMYM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34683
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968685
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35774
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862409
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0096
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988215
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30817
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114029
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13763
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24548
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868686
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64816
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46554
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3958
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921627
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12312
Sulfolithocholylglycine	HMDB Metabolites of Enzymes	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050757
A253	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87199
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43381
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KYAE1	DepMap CRISPR Gene Dependency	1.0	3.38457
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.944271
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)	Reactome Pathways 2014	1.0	null
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
medium-chain fatty acid catabolic process	GO Biological Process Annotations 2023	1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14755
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.64311
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Deoxycholic acid glycine conjugate	HMDB Metabolites of Enzymes	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE450	CCLE Cell Line Gene Mutation Profiles	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962185
Perturb_8649_KO_TBX5_SRP287180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.7116
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.029
HEC251	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02531
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22842
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.587336
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-1326-SM-4AD6V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09971
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49317
adrenal gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.826213
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4178
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endoplasmic reticulum	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-7775-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19131
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911418
Eye-adipocyte	Tabula Sapiens Gene-Cell Associations	1.0	6.56749
WM1799	CCLE Cell Line Gene CNV Profiles	1.0	2.17451
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15019
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Butyryl-CoA	HMDB Metabolites of Enzymes	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6881-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	3.17602
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.38746
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.98941
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839219
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6945
GTEX-Q2AG-0326-SM-48U1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78591
hsa-miR-96	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23318
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.16
cSARS Bat SRBD_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95396
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70888
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16781
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40921
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11825
697	CCLE Cell Line Gene Mutation Profiles	1.0	null
SLC38A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3514
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00024
Sarcoma_SARC_TCGA-DX-A8BQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2719-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4609
3-Phenylpropionylglycine	HMDB Metabolites of Enzymes	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3375
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.35791
hsa-miR-576-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66412
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75304
PMC11328671-jitc-12-4-s003.pdf-126-GLI4_GLI4	Rummagene Transcription Factor Associations 2026	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0522
placenta_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7925
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15406
GSE173169,GSE173170_0_v_1_epc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1187	CCLE Cell Line Gene Expression Profiles	1.0	1.34837
GTEX-T6MO-0326-SM-32QOK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31655
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56176
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24193
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7512
Acetylglycine	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-1271	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
placenta	HPA Tissue Gene Expression Profiles	-1.0	-1.16856
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889015
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Sarcoma_SARC_TCGA-VT-A80G-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965541
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06059
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.92067
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.25931
Brain Lower Grade Glioma_LGG_TCGA-DB-A75L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AB-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.98674
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051859
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8855
subthalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10195
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.87097
Premature aging_Skin fibroblast_GSE10123	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.31481
Prostate adenocarcinoma_PRAD_TCGA-HC-7817-01B-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00441
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33773
A-673 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BICR78	DepMap CRISPR Gene Dependency	1.0	2.83106
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19557
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08804
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8176
medium-chain fatty acid catabolic process	GO Biological Process Annotations 2025	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
(2E)-Decenoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8424-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glycocholic acid	HMDB Metabolites of Enzymes	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
PMC11459127-pnas.2406837121.sd04.xlsx-Sheet1-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
Trachea-goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	0.278484
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923433
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMK1-2626-SM-4B65R	GTEx Tissue Sample Gene Expression Profiles	1.0	3.30196
Vinylacetylglycine	HMDB Metabolites of Enzymes	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0985
HT115	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862365
cervix, uterine	HPA Tissue Protein Expression Profiles	1.0	0.760276
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9810535-41590_2022_1370_MOESM3_ESM.xlsx-Table_S3-MECOM_down_genes_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31482
Valerylglycine	HMDB Metabolites of Enzymes	1.0	null
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942923
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07119
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2172
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904015
hsa-miR-769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20125
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55459
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.39747
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.949456
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16663
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amino acid conjugation of benzoic acid(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49303
GTEX-OHPM-0226-SM-3LK61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2188
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
N-Acetyl-L-phenylalanine	HMDB Metabolites of Enzymes	1.0	null
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR16	CCLE Cell Line Gene Mutation Profiles	1.0	null
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04949
Conjugation of salicylate with glycine	Reactome Pathways 2014	1.0	null
Tetracosanoyl-CoA  	HMDB Metabolites of Enzymes	1.0	null
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60676
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16061
EW1	DepMap CRISPR Gene Dependency	1.0	2.60426
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
FOXA1_01_233	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.09128
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70878
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.874847
Conjugation of carboxylic acids	Reactome Pathways 2024	1.0	null
GSE116810_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.83717
SP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02115
N-acyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-XPVG-2026-SM-4B65E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95202
Sarcoma_SARC_TCGA-DX-A6B8-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.07189
hsa-miR-548f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1901
Defective GGT1 causes Glutathionuria (GLUTH)	Reactome Pathways 2014	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0103
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23409
A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.02546
2-Furoylglycine	HMDB Metabolites of Enzymes	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50712
hsa-miR-4720-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RDES	CCLE Cell Line Gene CNV Profiles	1.0	1.40739
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04173
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91953
MFE280	DepMap CRISPR Gene Dependency	1.0	7.17267
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Isovalerylglycine	HMDB Metabolites of Enzymes	1.0	null
Perturb_6689_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.45164
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.684517
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874212
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
characterization	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3007
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20032
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6297
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1686
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913544
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37596
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.80195
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4777532__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850127
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5FO-01A-21R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4011582-oncotarget-05-1052-s002.docx-3-Downregulated_in_CTCFL_BORIS_High_1_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1301
4-Aminohippuric acid	HMDB Metabolites of Enzymes	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.9657
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872159
report	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-N1-A6IA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DU145	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67075
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00159
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24151
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868291
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17051
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23156
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48952
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993266
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7638
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20337
Eicosanoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R7-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100291_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05279
496100614_PCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25732
Methylhippuric acid	HMDB Metabolites of Enzymes	1.0	null
GTEX-WYJK-1326-SM-3NB2T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977016
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-[(3a,5b,7a,12a)-3,7-dihydroxy-24-oxo-12-(sulfooxy)cholan-24-yl]-Glycine	HMDB Metabolites of Enzymes	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5934
A253	CCLE Cell Line Gene Mutation Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08388
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	4.40668
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895467
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14865
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36405
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0289
enzyme	GeneRIF Biological Term Annotations	1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.67256
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.233
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6828
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.37188
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3452
AGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6767
PMC12486367-Supplementary_Data2.pdf-246-NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
KNS81	CCLE Cell Line Gene Expression Profiles	1.0	1.45315
HCE4	DepMap CRISPR Gene Dependency	1.0	2.62857
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18098
GTEX-U3ZN-1926-SM-4DXSG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05785
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23552
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981065
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68B-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00043
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03211
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
APEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40535
linking	GeneRIF Biological Term Annotations	1.0	null
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
19933690-TableS1	GeneSigDB Published Gene Signatures	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43949
HEC1	DepMap CRISPR Gene Dependency	1.0	2.029
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0992
Glycine	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11358
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)	Reactome Pathways 2014	1.0	null
GTEX-W5WG-1026-SM-4LMIF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993306
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_3_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0646
CHAGOK1	CCLE Cell Line Gene Mutation Profiles	1.0	null
DCTN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20444
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23156
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36077
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N18TG2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.685
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HLaC-78 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.644
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.56998
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847072
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24109
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21543
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09229
MFE296	DepMap CRISPR Gene Dependency	1.0	3.27622
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50515
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.37909
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59555
Kidney renal clear cell carcinoma_KIRC_TCGA-3Z-A93Z-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11622
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061215
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02248
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
N-Acetylvaline	HMDB Metabolites of Enzymes	1.0	null
GTEX-QDT8-0626-SM-48TYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75547
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68933
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.0047
PMC6941881-mmc4.xlsx-IR_only_down_DEGs-List_of_DEGs_that_are_downregulated_upon_PRMT5_KD_only_in_IR_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr11_58816313_G_C_b38	GTEx eQTL 2025	1.0	1.37838
NCIH2171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49191
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.842711
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.965726
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4218
BT483	CCLE Cell Line Gene Mutation Profiles	1.0	null
HCC1954	CCLE Cell Line Gene Expression Profiles	1.0	2.65493
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61802
RERFLCSQ1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56268
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34046
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
VMRCLCD	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14454
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04829
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1748
KCTD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13943
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21189
SF126	CCLE Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56669
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44106
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870304
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888757
breast	GTEx Tissue Gene Expression Profiles	1.0	1.06391
Stearoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23109
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11192
GSE221577_1_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1034
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861081
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01709
Isobutyrylglycine	HMDB Metabolites of Enzymes	1.0	null
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33414
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875179
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCHACV	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
3a,7b,12a-Trihydroxyoxocholanyl-Glycine	HMDB Metabolites of Enzymes	1.0	null
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57342
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0442
JIYOYEP-2003	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42212
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40723
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07142
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866048
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Acrylyl-CoA	HMDB Metabolites of Enzymes	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AU565	CCLE Cell Line Gene Expression Profiles	1.0	1.54051
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945343
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00917
HCC2998	DepMap CRISPR Gene Dependency	1.0	5.61961
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13939
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058496
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4643
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16068
Sarcoma_SARC_TCGA-X6-A8C4-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Phase II conjugation	Reactome Pathways 2014	1.0	null
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8707_KD_SIRT1_SRP267968	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.44348
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1049
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15795
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.4652
Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WI4N-1426-SM-3LK7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938883
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0194
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.2298
PECAPJ15	CCLE Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2-Methylbutyrylglycine	HMDB Metabolites of Enzymes	1.0	null
GTEX-XUJ4-1926-SM-4BOOV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11324
N-Butyrylglycine	HMDB Metabolites of Enzymes	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837947
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13387
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897304
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23156
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9745
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06059
SK-N-DZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trachea-tracheal goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	3.49886
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80112
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844592
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.7716
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902645
FOXO1_01_321	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.79102
TIPRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19756
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929488
Lung squamous cell carcinoma_LUSC_TCGA-66-2787-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4672	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919862
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	7.18978
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-Acetylserine	HMDB Metabolites of Enzymes	1.0	null
appendices_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3356
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
MDA-MB-435S cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
Conjugation of benzoate with glycine	Reactome Pathways 2024	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960309
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5291
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28464
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901158
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5311
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nonanoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50851
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19765
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13914
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.39142
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89535
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29563
Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.5423
N-Acetylasparagine	HMDB Metabolites of Enzymes	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2665-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
COL16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15393
EZH2	ENCODE Transcription Factor Targets	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2345
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21151
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47148
Defective UGT1A1 causes hyperbilirubinemia	Reactome Pathways 2014	1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8513
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Salicyluric acid	HMDB Metabolites of Enzymes	1.0	null
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
monounsaturated fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.106
N-Arachidonoyl glycine	HMDB Metabolites of Enzymes	1.0	null
Gallic acid (hydrate)_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0148402
JHOM2B	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29772
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TE14	CCLE Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-581	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ARH77	DepMap CRISPR Gene Dependency	1.0	8.48272
GSE130620_1_v_0_kdm4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980755
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Apocrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4775-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTEN_KD_GDS2958_99_human_A431 - EPIDERMOID carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TE159T	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4UY-0726-SM-4AD6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06364
fatty acid catabolic process	GO Biological Process Annotations 2025	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09271
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920529
hsa-miR-3686	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Ewing's family tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866048
Tiglylglycine	HMDB Metabolites of Enzymes	1.0	null
NCIH226	DepMap CRISPR Gene Dependency	1.0	8.88695
GTEX-PSDG-1426-SM-48TD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50996
transferase activity	GO Molecular Function Annotations 2015	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37641
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88997
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59598
GTEX-RWS6-1926-SM-47JXY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3971
hsa-miR-548e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
OC316	CCLE Cell Line Gene Mutation Profiles	1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69357
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15694
DOK	DepMap CRISPR Gene Dependency	1.0	5.63259
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857459
SKNDZ	CCLE Cell Line Gene Mutation Profiles	1.0	null
Perturb_17332_KD_PUM2_SRP170955	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.3849
PADI4	ChEA Transcription Factor Targets	1.0	null
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947516
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	2.48346
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04738
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096024
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841811
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835839
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-2026-SM-4LVM3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.82651
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62697
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20347
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1271	CCLE Cell Line Gene Mutation Profiles	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27599
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14891
Hexanoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0865
TGBC11TKB	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18443
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993266
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00985
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0905
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57299
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02966
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868446
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221061
Swine testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
Larynx squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.279
GSE84678,GSE93902_1_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4959
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.333949
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13914
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111007
SNUC5	CCLE Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63996
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.17234
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-OV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19333
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3912
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3072
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45489
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8145
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883985
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1677
RUNX2	ChEA Transcription Factor Targets	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-CL-4957-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11423
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1016
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926334
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16365
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56352
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.6326
Skin-epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.211042
TCF4	ChEA Transcription Factor Targets	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36734
KG1	CCLE Cell Line Gene Expression Profiles	1.0	1.84966
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66136
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56904
Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38116
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3214
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17721
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)	Reactome Pathways 2014	1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901171
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07874
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00703
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853354
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37596
N-acyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-SE5C-2126-SM-4BRUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33965
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48521
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WH7G-2226-SM-3NMBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18341
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39188
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43293
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.146536
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3372-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832522
HS934T	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47428
LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Acetylcysteine	HMDB Metabolites of Enzymes	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3233
Hexanoylglycine	HMDB Metabolites of Enzymes	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050993
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.81236
gallbladder	HPA Tissue Gene Expression Profiles	1.0	1.60724
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
16818636-TableS1	GeneSigDB Published Gene Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1976
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TT	CCLE Cell Line Gene Mutation Profiles	1.0	null
Rhabdomyosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3204
TE5	CCLE Cell Line Gene CNV Profiles	1.0	2.61697
monounsaturated fatty acid metabolic process	GO Biological Process Annotations 2023	1.0	null
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00949
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.22996
SNUC1	DepMap CRISPR Gene Dependency	1.0	5.97384
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9989
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35536
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUDHL4	CCLE Cell Line Gene Mutation Profiles	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05189
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01304
Chordoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05769
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4555
PANC0813	CCLE Cell Line Gene CNV Profiles	1.0	1.46848
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04221
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.96111
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2291	CCLE Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5499-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transferase activity, transferring acyl groups	GO Molecular Function Annotations 2015	1.0	null
Rhabdomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01078
Apocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02833
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68527
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6648
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17313
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03686
BT20	CCLE Cell Line Gene Expression Profiles	1.0	1.75782
lncap cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551695
n-acyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828338
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3402
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.00095
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57621
hsa-miR-4771	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63556
molecular_function	GO Molecular Function Annotations 2015	1.0	null
vcap cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.56867
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NL-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40509
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21561
Decanoyl-CoA (n-C10:0CoA)	HMDB Metabolites of Enzymes	1.0	null
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01738
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00707
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.862
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.41366
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964835
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18568
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A685-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	2.43338
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.254
N-Acetyl-L-tyrosine	HMDB Metabolites of Enzymes	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59094
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991204
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNUC5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.45696
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895716
PMC4777532__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMS454	CCLE Cell Line Gene Mutation Profiles	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36523
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.029
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02532
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.993589
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42627
Lung squamous cell carcinoma_LUSC_TCGA-22-4607-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058594
Perturb_2816_KD_SUFU_SRP346101	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.3935
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.72325
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992549
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3914
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24593
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.87249
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57671
Conjugation of carboxylic acids	Reactome Pathways 2014	1.0	null
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2066	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posttranslational	GeneRIF Biological Term Annotations	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73708
Phase II - Conjugation of compounds	Reactome Pathways 2024	1.0	null
HTT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42932
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN443	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49633
Propionyl-CoA	HMDB Metabolites of Enzymes	1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00574
N-Acryloylglycine	HMDB Metabolites of Enzymes	1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25347
ES8	DepMap CRISPR Gene Dependency	1.0	8.22209
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34488
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98529
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1049
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3851
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824729
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15373
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.19443
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1049
Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.914511
hsa-miR-548ah	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE84678,GSE93902_3_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4731
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913275
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8347
myc_17159920_cancer_cell_lines_lof_human_gpl570_gds2526	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.870826
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888798
TP53_01_175	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.86212
intracellular part	GO Cellular Component Annotations 2015	1.0	null
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Biological oxidations	Reactome Pathways 2014	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862409
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24159
KS1	CCLE Cell Line Gene Mutation Profiles	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863033
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pentanoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38665
PTEN_01_301	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.27033
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80658
Perturb_10411_KD_MAP3K7/CHD1_SRP310151	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.08481
SNU119	CCLE Cell Line Gene Mutation Profiles	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.4017
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30299
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47881
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50862
Notochordal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coenzyme A	HMDB Metabolites of Enzymes	1.0	null
Perturb_10189_KD_JMJD1C_SRP050058	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.748
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	Reactome Pathways 2014	1.0	null
GSE186647,GSE217288_11_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.70313
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14089
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68601
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33995
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27396
outer SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949804
VMRCLCP	CCLE Cell Line Gene Mutation Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15608
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831345
PMC3985196-317853.f1.pdf-26-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9810535-41590_2022_1370_MOESM3_ESM.xlsx-Table_S7-MECOM_down_genes_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828879
Hippuric acid	HMDB Metabolites of Enzymes	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TE11	CCLE Cell Line Gene CNV Profiles	1.0	1.75548
various	GeneRIF Biological Term Annotations	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945343
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4169
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86618
medium-chain fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87199
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881602
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945343
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.563311
Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vertebral endplate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.345
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824811
MAP3K11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04998
SNU1544	DepMap CRISPR Gene Dependency	1.0	3.10695
LS411N	DepMap CRISPR Gene Dependency	1.0	2.22103
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475034
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853354
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HO-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31362
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06248
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.36434
hsa-miR-3161	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3108
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73682
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.49773
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
PMC8350019-mmc3.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Capryloylglycine	HMDB Metabolites of Enzymes	1.0	null
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Phenylacetylglycine	HMDB Metabolites of Enzymes	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100408_PCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7527
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	1.17234
PMC9810535-41590_2022_1370_MOESM3_ESM.xlsx-Table_S2-Table_S2-MECOM_network_genes_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34105
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7638
Undecanoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
2-Methylhexanoyl-CoA 	HMDB Metabolites of Enzymes	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03445
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04449
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04149
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07123
Perturb_17334_OE_NANOS3_SRP216951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.8162
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15687
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63799
KS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10551
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28723
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2159
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964029
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LSM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31247
Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pristanoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
long-chain fatty acid catabolic process	GO Biological Process Annotations 2023	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55596
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4735-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4476
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24572
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.11807
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25283
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824812
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glycine N-acyltransferase, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
trans-2-Hexenoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
PMC8350019-mmc3.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
DGKZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03253
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051666
ZMIZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71363
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894428
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977078
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-1.10196
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23156
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26157
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.648661
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825103
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040781
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06277
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22353
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65185
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67129
N-Acetylglutamic acid	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pre-primosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60478
Bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56068
hsa-miR-4792	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7758
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKLMS1	CCLE Cell Line Gene Expression Profiles	1.0	1.40769
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81892
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.979461
icSARS CoV_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.56724
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.96816
Biological oxidations	Reactome Pathways 2024	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.14657
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56457
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.029
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939324
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5902-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11893
GTEX-TML8-1526-SM-4DXUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51725
LAN-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
N-Acetyl-L-alanine	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945343
Polycystic Ovary Syndrome_Adipose tissue_GSE5090	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.45115
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.3474
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61595
Heptadecanoyl CoA	HMDB Metabolites of Enzymes	1.0	null
skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51335
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70145
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15721
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.853622
Sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39259
hsa-miR-548a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13861
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44528
GTEX-RU72-0626-SM-46MUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1764
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)	Reactome Pathways 2014	1.0	null
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04474
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.42229
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5113-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99943
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48065
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72007
Prostate adenocarcinoma_PRAD_TCGA-V1-A8X3-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24081
Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0926-SM-4LVMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57448
ECC12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6492-01A-12R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-499a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07602
CCLFPEDS0008T	DepMap CRISPR Gene Dependency	1.0	3.91729
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937936
Lung squamous cell carcinoma_LUSC_TCGA-56-1622-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05935
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19572
A498	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34991
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991543
Larotrectinib sulfate_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0154717
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0778
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03629
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8431-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927714
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12942
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glycine N-acyltransferase, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	1.47544
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05186
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9707
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06131
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0146
Lithocholic acid glycine conjugate	HMDB Metabolites of Enzymes	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.17256
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973776
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852524
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEG01	CCLE Cell Line Gene Expression Profiles	1.0	1.39053
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855963
GTEX-XQ8I-1526-SM-4BOOH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82412
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984257
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32263
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29224
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47344
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990662
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898276
Defective UGT1A4 causes hyperbilirubinemia	Reactome Pathways 2014	1.0	null
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65391
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DC-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932812
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4773428-ncomms10751-s4.xlsx-S_Table_3-Supplementary_Data_3_497_common_genes_differentially_expressed_in_ER_breast_tumors_with_RUNX1_mutations_in_both_TCGA_and_Ellis_et_al_cohorts_FC_1_3_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36653
organelle	GO Cellular Component Annotations 2015	1.0	null
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lauroyl-CoA	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8387-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47174
LARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13655
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nicotinuric acid	HMDB Metabolites of Enzymes	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.629
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10031
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43913
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RIC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24338
3-Hydroxyhippuric acid	HMDB Metabolites of Enzymes	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1226-SM-32QON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50512
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27712
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992549
long-chain fatty acid metabolic process	GO Biological Process Annotations 2023	1.0	null
Phenylpropionylglycine	HMDB Metabolites of Enzymes	1.0	null
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26104
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0171
GTEX-X5EB-1726-SM-4E3J7	GTEx Tissue Sample Gene Expression Profiles	1.0	4.69826
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
long-chain fatty acid catabolic process	GO Biological Process Annotations 2025	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21108
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43023
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CWR22-Rv1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
Trachea-mucus secreting cell	Tabula Sapiens Gene-Cell Associations	1.0	1.20582
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8381
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68427
ETV6_01_91	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.6725
fatty acid catabolic process	GO Biological Process Annotations 2023	1.0	null
Acyl-CoA N-acyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0969
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4434	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04559
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28189
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.5425
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44583
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16456
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18653
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39587
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10731
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40254
GTEX-TMMY-0726-SM-33HBE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52008
WM983B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30388
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50515
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ACSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94815
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1074
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0697
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02966
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850464
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.372
HSC4	DepMap CRISPR Gene Dependency	1.0	4.75633
CW2	CCLE Cell Line Gene Mutation Profiles	1.0	null
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.38527
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55399
SKBR3	CCLE Cell Line Gene Expression Profiles	1.0	1.42134
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DOTC24510	DepMap CRISPR Gene Dependency	1.0	2.14853
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24341
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3913
NAMALWA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87904
(2E)-Octenoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918215
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.691708
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
20117289-Table2a	GeneSigDB Published Gene Signatures	1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.23446
HCC70	CCLE Cell Line Gene Expression Profiles	1.0	2.35827
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0546
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40138
SLC18A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06548
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06131
KMS34	DepMap CRISPR Gene Dependency	1.0	5.20042
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13168
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3685
N6-Acetyl-L-lysine	HMDB Metabolites of Enzymes	1.0	null
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	1.7155
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52946
monounsaturated fatty acid catabolic process	GO Biological Process Annotations 2023	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-SNOS-0626-SM-4DM5F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34967
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06773
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6219
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31998
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	2.18466
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2168
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02575
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3088
icSARS CoV_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.36994
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02833
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88263
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42016
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14051
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46066
Amino Acid conjugation	Reactome Pathways 2014	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18619
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.92366
prednisolone_homo sapiens_gpl570_gse32962	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16488
A-CA-04-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.61643
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62508
Chenodeoxycholic acid glycine conjugate	HMDB Metabolites of Enzymes	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8943
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11684
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
d17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
U138MG	CCLE Cell Line Gene Expression Profiles	1.0	1.36408
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.446
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60927
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3429-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-[(3a,5b,7b)-7-hydroxy-24-oxo-3-(sulfooxy)cholan-24-yl]-Glycine	HMDB Metabolites of Enzymes	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877243
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.866707
(2E)-Hexadecenoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
N-Acetyl-L-aspartic acid	HMDB Metabolites of Enzymes	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1293
SNU349	CCLE Cell Line Gene Expression Profiles	1.0	1.65775
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
KU1919	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33347
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
(2E)-Dodecenoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46725
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03079
PR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
Conjugation of salicylate with glycine	Reactome Pathways 2024	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862409
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Conjugation of benzoate with glycine	Reactome Pathways 2014	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824548
KPL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3781
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45299
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02008
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16818636-TableS2	GeneSigDB Published Gene Signatures	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14755
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03762
MM127	DepMap CRISPR Gene Dependency	1.0	3.39219
PMC7875385-pgen.1008540.s022.xlsx-AR_ChEA-Genes_differentially_expressed_with_MED19_overexpression_in_the_presence_of_androgens_that_are_AR_targets_from_ChEA_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6876
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Metabolism	Reactome Pathways 2014	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02833
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48706
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945675
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16199
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	1.0	3.19519
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43865
GSE185865_0_v_1_celf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.93983
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03593
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.43875
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24099
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83476
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01838
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0566
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14116
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35493
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
DMS79	CCLE Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8982
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19859
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
(2E)-Tetradecenoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medium-chain fatty acid metabolic process	GO Biological Process Annotations 2023	1.0	null
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0981
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09996
PMC5303304-13073_2017_407_MOESM3_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S2_Genes_differentially_expressed_by_24h_RA_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052944
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.82846
production	GeneRIF Biological Term Annotations	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6629
Glycoursodeoxycholic acid	HMDB Metabolites of Enzymes	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4015
trans-Octadec-2-enoyl-CoA	HMDB Metabolites of Enzymes	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901158
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33551
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10301
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23943
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33267
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13061
HCC1599	CCLE Cell Line Gene Expression Profiles	1.0	1.63336
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.828618
Perturb_2818_OE_SUFU_SRP346101	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.58951
Isovaleryl-CoA	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
glycine N-acyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824149
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.4498
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.193
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5048
N-[(3a,5b,7a)-3-hydroxy-24-oxo-7-(sulfooxy)cholan-24-yl]-Glycine	HMDB Metabolites of Enzymes	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.53717
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874482
E4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19983
Pyrimidine metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Glutaconyl-CoA	HMDB Metabolites of Enzymes	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79818
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966742
Basophilic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53115
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986325
testis_7a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6244