association	dataset	threshold value	standardized value
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5748
Intraductal papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nrd1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0587
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7773-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	4.23339
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4368
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1698
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9269
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38019
CCNT2	ENCODE Transcription Factor Targets	1.0	null
PRDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32539
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17213
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	2.17258
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Valerylglycine	HMDB Metabolites of Enzymes	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0411
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840132
PPP2R1A	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3152-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.15638
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70613
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25152
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4397
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79454
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7957
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29666
HS683	DepMap CRISPR Gene Dependency	1.0	2.42888
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841668
GSE151471_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung disease	GWASdb SNP-Disease Associations	1.0	0.66115
dementia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0926
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833741
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.434
hsa-miR-3606	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
HEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31482
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.95
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914901
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7741
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11315
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.2107
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859917
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5535
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.314
CCT4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8789
cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.6688
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0453
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	1.21019
hsa-miR-154	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60589
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.15215
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0934
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.74257
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
U937	CCLE Cell Line Gene CNV Profiles	1.0	1.90408
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17306
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.177
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYRM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.95925
colon	GTEx Tissue Gene Expression Profiles	1.0	1.06308
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28509
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-380	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04154
FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74999
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7518
NASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28812
brain	GAD Gene-Disease Associations	1.0	null
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25941
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13421
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25152
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.33567
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35854
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4727
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75218
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3373
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
NPY5R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35807
SOX4-29892750-EML-MOUSE-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	2.33434
FHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83137
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2102
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86597
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3298
PPP4C	Pathway Commons Protein-Protein Interactions	1.0	null
BORCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49422
RPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48794
PJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30598
HCC2814	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44828
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
UMRC7	DepMap CRISPR Gene Dependency	1.0	3.82012
hsa-miR-885-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0304
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.33963
N-[(3a,5b,7a,12a)-3,7-dihydroxy-24-oxo-12-(sulfooxy)cholan-24-yl]-Glycine	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927455
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37288
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6011
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62937
CHAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96183
Lung squamous cell carcinoma_LUSC_TCGA-98-8023-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2448
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1421
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1087
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69918
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04813
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62058
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0554
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23438
SLC2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2517
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19707
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7724
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6048
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18187
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.32822
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48982
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4348
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77317
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2125
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08161
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0459
GSE174701_4_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1121
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3839
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5802
SPIN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65284
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hsa-miR-579	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
DNAJC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90933
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64192
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1279
TIS granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30287
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09956
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
CARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6871
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-412	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	84.3195
SAP30	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-8500-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93998
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55247
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7851
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1209
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970715
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03894
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.940477
PMC8640960__F3	PFOCR Pathway Figure Associations 2024	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0902
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.837019
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9424
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3684
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66643
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72652
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32272
hsa-miR-411	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17038
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0079
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26651
PANC-02-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24654
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858922
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08532
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50097
d17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9004
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30664
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8893
CDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4569
Perturb_4015_KO_Adam10_SRP168247	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.07295
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	2.14861
N-acyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95837
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6417
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.956
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14801
GPX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4158
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10115
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34811
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96052
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08363
PTPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.01
GATA3	ENCODE Transcription Factor Targets	1.0	null
stomach	HPA Tissue Protein Expression Profiles	-1.0	-1.1813
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82949
NCIH661	CCLE Cell Line Gene CNV Profiles	1.0	1.45269
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93998
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3709
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
molecular_function	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-548y	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3698
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39574
N-[(3a,5b,7b)-7-hydroxy-24-oxo-3-(sulfooxy)cholan-24-yl]-Glycine	HMDB Metabolites of Enzymes	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
HMGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08779
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.033749
496100475_TCx_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.41015
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01855
hsa-miR-1258	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58251
SUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50538
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01003
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6671
3-Hydroxyhippuric acid	HMDB Metabolites of Enzymes	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3001-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7037
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.399
hsa-miR-548w	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
NB1	DepMap CRISPR Gene Dependency	1.0	2.22439
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74405
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96195
Sto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
RTN4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55911
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
FOXO3	ChEA Transcription Factor Targets	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.1702
N-[(3a,5b,7a,12a)-3,12-dihydroxy-24-oxo-7-(sulfooxy)cholan-24-yl]-Glycine	HMDB Metabolites of Enzymes	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44686
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6954-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
disease	GWASdb SNP-Disease Associations	1.0	0.033177
UMUC16	DepMap CRISPR Gene Dependency	1.0	10.0431
hsa-miR-3173-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
HUT78	CCLE Cell Line Gene CNV Profiles	1.0	1.38212
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.078156
PMC10274745-media-4.xlsx-S3A-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05417
hsa-miR-548aa	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5689
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
B3GNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7156
central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0617
Lung squamous cell carcinoma_LUSC_TCGA-68-8251-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14764
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.73026
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17092
hsa-miR-1915	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2188
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892299
PPP2R5D	Pathway Commons Protein-Protein Interactions	1.0	null
Wing disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30651
n-acyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
N-acyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5061
HEC-1-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31017
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94817
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1495
hsa-miR-1306	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15204
NO11	DepMap CRISPR Gene Dependency	1.0	5.68648
personality disorder	GWASdb SNP-Disease Associations	1.0	0.758489
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48574
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6957
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26785
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	2.90928
BAZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7048
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998848
Perturb_14502_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.09944
glycine N-acyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33898
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67747
hsa-miR-3144-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8651
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08715
A498	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53745
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39506
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30287
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MICALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59955
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain structure	GWAS Catalog SNP-Phenotype Associations	1.0	0.238523
hsa-miR-3925-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-1278	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hsa-miR-4685-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ZSCAN5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53968
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2553
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.114834
Aspirin ADME	Reactome Pathways 2024	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMB	DepMap CRISPR Gene Dependency	1.0	2.05768
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8684
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87188
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8303
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69977
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.15638
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55232
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847784
PGAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7623
GSE157904_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0368
Perturb_9719_OE_Wt1_SRP126738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.30564
Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.039
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27205
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88779
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.102294
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160293_3_v_1_celf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2774
ZNF467	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65467
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89805
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
N-[(3a,5b,7a)-3-hydroxy-24-oxo-7-(sulfooxy)cholan-24-yl]-Glycine	HMDB Metabolites of Enzymes	1.0	null
NDUFA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03598
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8344
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.84852
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922816
T3M5	DepMap CRISPR Gene Dependency	1.0	2.0306
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02087
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
PPP4R2	Pathway Commons Protein-Protein Interactions	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.30999
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13421
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09865
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7355
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65445
Brain	dbGAP Gene-Trait Associations	1.0	0.518003
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4759
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-770-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7S9-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood microparticle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09186
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.48094
Perturb_9459_KO_Srsf3_SRP143519	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.92715
TEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49707
CHK1_KD_GSE54268_666_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.827
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.894
BL70	DepMap CRISPR Gene Dependency	1.0	5.2058
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48456
cellular_component	GO Cellular Component Annotations 2015	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70094
TBP	ENCODE Transcription Factor Targets	1.0	null
Suberylglycine	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940727
hsa-miR-548ab	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.177
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0693
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.916358
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7945
tauopathy	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5132
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83933
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
transferase activity, transferring acyl groups	GO Molecular Function Annotations 2015	1.0	null
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6056
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864998
REST	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4684-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
NGP	DepMap CRISPR Gene Dependency	1.0	2.92838
Perturb_2199_KO_Krit1_SRP173638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.78439
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37173
hsa-miR-4324	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88726
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51875
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.7969
CTCF	ENCODE Transcription Factor Targets	1.0	null
LRRC4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19367
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53897
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7678
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.13584
Perturb_13273_KO_Spen_SRP198728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.5482
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0215
NCOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5472
HCC202	DepMap CRISPR Gene Dependency	1.0	2.00142
Myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
4-Aminohippuric acid	HMDB Metabolites of Enzymes	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6966
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
PPP4R4	Pathway Commons Protein-Protein Interactions	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9431
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44238
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transferase activity, transferring acyl groups other than amino-acyl groups	GO Molecular Function Annotations 2015	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995024
Perturb_9714_KO_miR34a_SRP058984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.64991
ZFP69B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34106
hsa-miR-340	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6345
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81965
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05417
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30757
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35213
Phase II - Conjugation of compounds	Reactome Pathways 2024	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Lithocholic acid glycine conjugate	HMDB Metabolites of Enzymes	1.0	null
Hexanoylglycine	HMDB Metabolites of Enzymes	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4309
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30631
HSQ89	DepMap CRISPR Gene Dependency	1.0	2.30041
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35987
PMC10823279-CAS-115-283-s001.xlsx-Table_S6-Table_S6_List_of_182_genes_particularly_down-regulated_by_AR_in_AILNCaP14_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86776
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.216161
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP1N	DepMap CRISPR Gene Dependency	1.0	2.03819
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5977
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30161
FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-3153	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1718
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.29056
RPL29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15908
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5529
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23779
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34942
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842487
MYBPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83288
hsa-miR-3663-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0154
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.66316
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
NCIH82	DepMap CRISPR Gene Dependency	1.0	3.07506
KYSE150	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34717
VIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.635
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42291
Deoxycholic acid glycine conjugate	HMDB Metabolites of Enzymes	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6243
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65705
Breast carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20928
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5333
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0331
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00441
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.346
hsa-miR-3925-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.7274
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
Hydroxyphenylacetylglycine	HMDB Metabolites of Enzymes	1.0	null
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0836
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33419
all	GWASdb SNP-Phenotype Associations	1.0	0.03367
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1217
EP300	ENCODE Transcription Factor Targets	1.0	null
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49196
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6972
ZBTB33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66627
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE195663_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7788
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38307
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-548b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
hsa-miR-548i	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892299
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5475
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93998
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86499
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28399
RGL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78106
COLO792	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0175
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3931
GP5D	DepMap CRISPR Gene Dependency	1.0	2.04833
ZNF623	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54483
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.604
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65057
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4059
JMSU1	DepMap CRISPR Gene Dependency	1.0	2.53777
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7412
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	1.15638
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5593
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67154
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75055
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.45381
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4643-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98238
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A184-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26374
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14589
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06382
hsa-miR-448	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Prostate adenocarcinoma_PRAD_TCGA-G9-6499-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92256
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41292
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1456
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20929
TP53BP1_KD_GSE54268_669_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-2.46499
Perturb_5340_KO_Dnmt1/Dnmt3a/Dnmt3b_SRP337936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.75722
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.036097
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829592
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990966
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63176
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SK-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41666
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34507
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892299
Imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964485
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995515
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38179
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39506
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
TC138	DepMap CRISPR Gene Dependency	1.0	2.42347
Perturb_4669_OE_Wdr5/Trp53|Wdr5_SRP324834	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.8546
AP1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95469
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93998
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.54229
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
Capryloylglycine	HMDB Metabolites of Enzymes	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0435
PLCXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25405
MFE296	DepMap CRISPR Gene Dependency	1.0	4.2963
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Comedo carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.009
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7138
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.57
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.42
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1356
hsa-miR-4691-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
HOS	CCLE Cell Line Gene CNV Profiles	1.0	2.4922
CCDC6	Pathway Commons Protein-Protein Interactions	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.8124
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877465
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-579	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18596
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1876
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841668
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14818
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45215
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33804
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09543
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979456
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54552
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4789
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3667
HCC1806	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1313
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05389
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57167
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56517
MEC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48959
hsa-miR-559	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
GSE255680_2_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45414
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7788
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
hsa-miR-4528	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.19112
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.889
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HO-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11328671-jitc-12-4-s003.pdf-126-GLI4_GLI4	Rummagene Transcription Factor Associations 2026	1.0	null
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83625
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12798
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.89576
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87493
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85835
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
HCE4	DepMap CRISPR Gene Dependency	1.0	6.19983
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940727
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7305
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
JURKAT	DepMap CRISPR Gene Dependency	1.0	4.65132
TTC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50221
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.56381
hsa-miR-548c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
Breast invasive ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.33529
SET2	DepMap CRISPR Gene Dependency	1.0	5.18536
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85829
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
Perturb_4943_OE_Hoxa13_SRP316002	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.64192
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SI-01A-31R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07038
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3161
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
hsa-miR-548d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1366
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.443
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2498
alzheimer's disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95766
Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABCB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6962
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.27531
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892299
SNU46	DepMap CRISPR Gene Dependency	1.0	3.13996
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12688
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841668
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00057
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42689
FABP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78243
Glycine N-acyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70944
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2348
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
N-Acryloylglycine	HMDB Metabolites of Enzymes	1.0	null
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01015
ANKRD16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85327
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.910003
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Phenylpropionylglycine	HMDB Metabolites of Enzymes	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65337
KIAA1671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73023
AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21451
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48509
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93431
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6453
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941385
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13515
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45807
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.3185
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909174
hsa-miR-4518	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZFP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90916
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26763
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7037
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991045
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73065
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60267
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7364-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47908
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61791
hsa-miR-548h	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7944
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40874
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33898
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93998
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0961
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0647
POLR2A	ENCODE Transcription Factor Targets	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868559
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61925
TOX_01_332	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59023
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55841
hsa-miR-664	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.920313
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22091
MTHFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89327
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2307
VP229	DepMap CRISPR Gene Dependency	1.0	3.04041
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99515
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58372
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51489
EFR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53318
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85792
MOB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89679
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1576
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30287
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907032
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.8084
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
HT1197	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54604
Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66462
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JHUEM3	CCLE Cell Line Gene CNV Profiles	1.0	1.74107
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7383
Perturb_9718_OE_Wt1_SRP126738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.79535
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2784
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73006
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
hsa-miR-107	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52785
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0225
SMEK2	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33817
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	6.7076
Perturb_5482_KD_Ctnnb1_SRP130920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.4671
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.95162
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4755
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30117
hsa-miR-146b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
EPLC-272H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	1.15638
hsa-miR-4519	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5051
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9677
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37669
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2976
FBXW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59547
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25118
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84351
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
SNU668	DepMap CRISPR Gene Dependency	1.0	2.50296
PMC10260405-41588_2023_1409_MOESM6_ESM.xlsx-ST12-Supplementary_Table_12_Most_likely_causal_genes_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
MTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.564644
Perturb_5154_KO_Dcr_SRP038929	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.1543
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6765
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-365	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.738
Mesocorticolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0312
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66235
HEY	DepMap CRISPR Gene Dependency	1.0	2.34435
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
Brain structure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.609691
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0363
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
U2904	DepMap CRISPR Gene Dependency	1.0	4.52198
2-Methylbutyrylglycine	HMDB Metabolites of Enzymes	1.0	null
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.10575
PANC0327	CCLE Cell Line Gene CNV Profiles	1.0	1.61539
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17969
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23636
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
GTF3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42295
glycine n-acyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09844
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7964
PSMB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7255
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846132
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0242
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.42753
EZH2	ENCODE Transcription Factor Targets	1.0	null
Amino Acid conjugation	Reactome Pathways 2024	1.0	null
Mammary ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.10364
Salicyluric acid	HMDB Metabolites of Enzymes	1.0	null
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.41635
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Glycine N-acyltransferase, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-4729	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.144216
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26527
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.196317
Conjugation of benzoate with glycine	Reactome Pathways 2024	1.0	null
SUM149PT	DepMap CRISPR Gene Dependency	1.0	2.07731
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01453
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00234
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4278_KO_Nr2f1_SRP149321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.57323
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	2.42256
LU165	DepMap CRISPR Gene Dependency	1.0	6.2257
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.3553
ZSCAN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1641
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67607
Isovalerylglycine	HMDB Metabolites of Enzymes	1.0	null
Vinylacetylglycine	HMDB Metabolites of Enzymes	1.0	null
GSE211744_2_v_0_gdf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91358
CHST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80115
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.08759
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36738
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10113
glycine N-acyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-BRCA_AND_UCEC_NOT_CESC_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3455
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.9488
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898092
CELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08673
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12685
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.414
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sulfolithocholylglycine	HMDB Metabolites of Enzymes	1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73436
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.888
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8745
Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06062
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100590_FWM_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.71688
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1332
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78632
Methylhippuric acid	HMDB Metabolites of Enzymes	1.0	null
CHK1_KD_GSE54268_665_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.02548
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03078
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59085
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83573
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51N-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49616
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.04344
dementia	GWASdb SNP-Disease Associations	1.0	0.441184
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83252
KLF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56818
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
127399	DepMap CRISPR Gene Dependency	1.0	2.08533
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO-741	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70518
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48901
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67382
hsa-miR-548j	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
ES8	DepMap CRISPR Gene Dependency	1.0	5.54223
GSE93918_1_v_0_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_13247_KO_Cdk8_SRP190900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.68389
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.142685
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	1.05869
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.264
hsa-miR-3168	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC4021073-1471-2407-14-278-S4.xlsx-Sheet1-Supplementary_Table_S5_Genes_with_GATA3_ChIP-seq_peak_within_10kb_from_transcription_start_site_TSS_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
3-Phenylpropionylglycine	HMDB Metabolites of Enzymes	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3512
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6754
Hippuric acid	HMDB Metabolites of Enzymes	1.0	null
SKNEP1	DepMap CRISPR Gene Dependency	1.0	3.93876
SPEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96379
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7806
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02221
HMGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70559
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	2.14289
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9339
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25315
SUDHL8	CCLE Cell Line Gene CNV Profiles	1.0	1.50915
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6591
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0102
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.89576
Biological oxidations	Reactome Pathways 2024	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0301
TNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07636
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
CCDC120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76423
IL13RA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71068
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
2-Furoylglycine	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-4273	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
testis	HPA Tissue Protein Expression Profiles	1.0	1.15638
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5501
SKPNDW	DepMap CRISPR Gene Dependency	1.0	4.04435
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9869
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.5966
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.097381
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8753
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-11A-12R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Conjugation of salicylate with glycine	Reactome Pathways 2024	1.0	null
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68293
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4388
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2437
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35436
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80658
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24429
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
Intraductal breast benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
hsa-miR-3123	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BZW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74832
hsa-miR-3157-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9679
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8115
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37451
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3303
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2622
biological_process	GO Biological Process Annotations 2015	1.0	null
PPP4R1	Pathway Commons Protein-Protein Interactions	1.0	null
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.07063
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-186	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1925
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13154
hsa-miR-103a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
neurodegenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48356
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.256
FOXL2NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52779
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55068
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28847
metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10517
LBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60583
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93826
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44164
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2253
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.22398
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44618
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33545
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850224
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88138
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23639
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30401
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31721
Perturb_17277_KO_Kdm1a_SRP185978	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.12422
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1295
YAPC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82949
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7594
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03841
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47355
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-548a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2197
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25479
Perturb_1387_KO_IPO13_SRP128496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.16795
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61111
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8553
hsa-miR-1266	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844785
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-11A-12R-A26B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56063
hsa-miR-548ak	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59025
SNU449	DepMap CRISPR Gene Dependency	1.0	3.70692
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64514
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37441
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7894
Urinary metabolite levels in chronic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
BRD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59535
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92441
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828842
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ductal carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
3-Methylcrotonylglycine	HMDB Metabolites of Enzymes	1.0	null
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
hsa-miR-3153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.062555
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9779
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FAM217B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65259
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NP-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug ADME	Reactome Pathways 2024	1.0	null
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7147
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865594
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.072261
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39635
Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
VMRC-LCD	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.44099
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.89576
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1523
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53983
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3727
PMC11193738-41467_2024_48647_MOESM8_ESM.xlsx-Data_S5-Data_S5_HNF4A-bound_gene_targets_identified_from_ChIP-Seq_in_hepatic_cells_D8_Hep_and_HepG2_cells_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2125
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.33963
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93313
HOS	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.154828
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33874
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.15638
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.4151
FAR/SIN/STRIPAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.259
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7524
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94127
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3773
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6012
YKT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61958
outer CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871333
brain structure	GAD Gene-Disease Associations	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891384
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06676
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29489
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13933
697	DepMap CRISPR Gene Dependency	1.0	3.81987
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40915
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12565
LN235	DepMap CRISPR Gene Dependency	1.0	3.07245
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0586
Perturb_5100_KO_Zmym2_SRP161512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.87911
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5342
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13421
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0286
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31956
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46821
PA1	DepMap CRISPR Gene Dependency	1.0	3.63405
COLO205	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51326
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09164
NDUFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58059
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37317
Glycine N-acyltransferase, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9742
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94057
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.93463
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15824
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.21
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75636
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.8887
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4412
SMEK1	Pathway Commons Protein-Protein Interactions	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89891
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
DOK	DepMap CRISPR Gene Dependency	1.0	3.40308
RNASET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35287
3a,7b,12a-Trihydroxyoxocholanyl-Glycine	HMDB Metabolites of Enzymes	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09479
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4712-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26792
BMAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6874
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7485
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7747
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6753
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tiglylglycine	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
hsa-miR-4655-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862394
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1905
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07547
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0313
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.01585
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1475
Isobutyrylglycine	HMDB Metabolites of Enzymes	1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Nicotinuric acid	HMDB Metabolites of Enzymes	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5731
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.16224
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13625
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99977
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93998
DMXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13918
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4452
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58171
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841668
Chenodeoxycholic acid glycine conjugate	HMDB Metabolites of Enzymes	1.0	null
Glycocholic acid	HMDB Metabolites of Enzymes	1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.7328
MKN45	CCLE Cell Line Gene CNV Profiles	1.0	1.50428
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
personality disorder	GWASdb SNP-Phenotype Associations	1.0	0.656743
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.374
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43885
HCE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28256
Sarcoma_SARC_TCGA-DX-A3UA-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glycoursodeoxycholic acid	HMDB Metabolites of Enzymes	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9287
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6343
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP2K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894579
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.994553
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZT-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5665
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1771
Mesolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2985
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8552
PTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19911
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82628
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24481
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89934
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9138
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962507
hsa-miR-4656	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0932
SET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8673
prostate	HPA Tissue Protein Expression Profiles	1.0	1.15638
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47984
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63059
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892299
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4981_KO_Kmt2d_SRP107208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.87212
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81683
hsa-miR-3920	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.233
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19331
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3361
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR89A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92025
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21002
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93998
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8566
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07637
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9648
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5915
tauopathy	GWASdb SNP-Disease Associations	1.0	1.21019
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96692
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.545
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5746
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32869
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Propionylglycine	HMDB Metabolites of Enzymes	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921256
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.110689
PMC4872073-supp_gkv1528_nar-02930-x-2015-File004.xlsx-Table_S2C-CREB1_FoxA1_Target_Genes_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
liver	GTEx Tissue Gene Expression Profiles	1.0	1.42523
Conjugation of carboxylic acids	Reactome Pathways 2024	1.0	null
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81989
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33412
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7293
PSMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84611
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04207
organelle	GO Cellular Component Annotations 2015	1.0	null
Glutarylglycine	HMDB Metabolites of Enzymes	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.4392
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
ZNF354A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7459
Metabolism	Reactome Pathways 2024	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-1.01585
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64492
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
N18TG2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.546
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0303
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-146a	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
NCI-H2172	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6391
Phenylacetylglycine	HMDB Metabolites of Enzymes	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7645-01A-22R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-Butyrylglycine	HMDB Metabolites of Enzymes	1.0	null
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83176
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acyl-CoA N-acyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.786
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926479
COLO824	DepMap CRISPR Gene Dependency	1.0	6.36358
Perturb_4683_KO_Mll2/Suz12_SRP189864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.48949
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63059
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9852
MM253	DepMap CRISPR Gene Dependency	1.0	4.67225
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null