association dataset threshold value standardized value Perturb_6_KO_Rnf114_SRP301146 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.78798 paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78882 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.81919 RCOR1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.900296 MXI1 ENCODE Transcription Factor Targets 1.0 null 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.966188 U118MG DepMap CRISPR Gene Dependency 1.0 2.47805 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054886 male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Ovarian fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.761 Dentate gyrus, granule cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53441 OVMIU DepMap CRISPR Gene Dependency 1.0 4.22062 CEBPA-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCIH1581 CCLE Cell Line Gene CNV Profiles 1.0 1.65776 GSE182921_0_v_1_slit2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null transferase activity GO Molecular Function Annotations 2015 1.0 null GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null plastid envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.468001 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.232744 root nodule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.263327 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZR751 CCLE Cell Line Gene CNV Profiles 1.0 1.8765 APOBEC3G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89653 inferior occipital gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.962622 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.92594 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46635 plastid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.544411 periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.19292 amygdalohippocampal transition zone, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.49013 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.08067 L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930798 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.074925 aspartate family amino acid biosynthetic process GO Biological Process Annotations 2023 1.0 null cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.60444 Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.56552 SMAD1 ChEA Transcription Factor Targets 1.0 null neither GeneRIF Biological Term Annotations 1.0 null ZFX ChEA Transcription Factor Targets 1.0 null OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68332 HT29 CCLE Cell Line Gene CNV Profiles -1.0 -2.32856 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64125 NCIH1339 CCLE Cell Line Gene Expression Profiles -1.0 -1.89038 Fibrosis CTD Gene-Disease Associations 1.0 1.03345 DANG CCLE Cell Line Gene CNV Profiles 1.0 2.09412 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.0437 ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3259 REEP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96021 SREBF1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE179002_0_v_1_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09968 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Interrenal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.519 intermediate stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07198 Lassa Fever Virus_4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.18533 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TSSK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03578 ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CORL88 CCLE Cell Line Gene CNV Profiles 1.0 1.5048 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nuclear inclusion body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.589 dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.977197 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.88898 SALL4 ChEA Transcription Factor Targets 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16321 Arginine and proline metabolism KEGG Pathways 2026 1.0 null periventricular stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32549 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE112761,GSE112767_1_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Leukemialymphoblastic(MOLT-4) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.4748 CTCF_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null thorax TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060073 Chloroplast chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.281 KG-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34184 SHISA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.16347 isthmic roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77536 496100630_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.49628 CAMA-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.493122 SNU81 DepMap CRISPR Gene Dependency 1.0 2.11689 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 325.206 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04228 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01913 RBBP5 ENCODE Transcription Factor Targets 1.0 null REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV2-25802403-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.882952 Kwashiorkor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.238 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.82979 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13976_KO_H3f3a/H3f3b_ERP109384 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45037 KPNYN DepMap CRISPR Gene Dependency 1.0 2.22865 juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.257907 GSE144115_1_v_3_stag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCIH1781 CCLE Cell Line Gene CNV Profiles -1.0 -1.55329 PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR7-List_of_differentially_expressed_genes_in_AR11_vs_AR7_Negative_value_means_down-regulation_in_AR11_THRA Rummagene Transcription Factor Associations 2026 1.0 null HCC-56 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 130.547 JcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20701 CMLT1 CCLE Cell Line Gene Expression Profiles -1.0 -1.98848 Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94335 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null DKMG CCLE Cell Line Gene Expression Profiles 1.0 1.39639 serum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.664368 Miracidium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.916 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.899777 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A4TM-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883178 EFM-192A COSMIC Cell Line Gene Mutation Profiles 1.0 null differentially GeneRIF Biological Term Annotations 1.0 null dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.914648 SYNGR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42307 fusiform gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14972 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null BICR31 CCLE Cell Line Gene Expression Profiles 1.0 1.35899 NCI-H2444 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 intermediate stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17364 hippocampus (hippocampal formation)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.952633 Brain ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.88497 periventricular stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79289 molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0083 mRNA_SALL4_19060217 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE179002_2_v_7_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE196699_2_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044656 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.93402 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.40164 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045902 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 bacteroid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.692493 ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5995 dorsolateral isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28068 ZNF416 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71222 phloem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.558457 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78833 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.913073 stele TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.287447 CAL33 CCLE Cell Line Gene CNV Profiles -1.0 -1.40763 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.843286 CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61541 Ventral part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.97744 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05161 RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8903 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Glutamate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.865 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6625 Hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE220520_6_v_8_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE153064,GSE153065_1_v_0_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09177 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040564 ChIP_SMAD1_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null flower TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.17375 vascular tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.178807 SMAD1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null reye syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.03577 inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041865 RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.983545 GSE220520_1_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.26745 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.825065 HUCCT1 CCLE Cell Line Gene Expression Profiles -1.0 -1.53883 FEV JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6701 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0245 PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Ensemble_gene_ID_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null WHSC1 ENCODE Transcription Factor Targets 1.0 null GATA1_G1E-ER4_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE179002_0_v_8_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BV173 CCLE Cell Line Gene CNV Profiles 1.0 1.57878 hepatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.138236 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.10304 ZCCHC24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35978 SKNMC CCLE Cell Line Gene CNV Profiles 1.0 1.3435 Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11331 HCC2279 CCLE Cell Line Gene CNV Profiles -1.0 -1.37939 REST ENCODE Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2950-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923784 JIMT-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 Plastid nucleoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.722 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.964129 SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95459 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Histidinemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.016 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887423 Skeletal muscle satellite cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.698 metabolic process GO Biological Process Annotations 2015 1.0 null FABP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01692 fusiform gyrus, left, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01572 TGFBR2_knockout_293_GSE46211 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.747 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE173578_1_v_0_atf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73785 HCC78 CCLE Cell Line Gene Expression Profiles -1.0 -1.54871 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.0307 CDC42EP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30567 GSE71674,GSE71676_0_v_2_cbfa2t2_mouse RummaGEO Gene Perturbation Signatures 1.0 null LMSU CCLE Cell Line Gene CNV Profiles 1.0 1.42843 Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.245 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.200656 striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.885424 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.02289 Large_Intestine-intestinal crypt stem cell of large intestine Tabula Sapiens Gene-Cell Associations 1.0 0.0 Aspartate/other aminotransferase InterPro Predicted Protein Domain Annotations 1.0 null intermediate stratum of PThE Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27333 Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.10208 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.825776 Primary somatosensory area, lower limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11776 Atherosclerosis CTD Gene-Disease Associations 1.0 1.02671 CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Plant vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.728 SRF_KO_GDS3732_148_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Coronary artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.281 Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ventrolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.109 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52159 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE112760,GSE112767_4_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.3748 FOXF2 JASPAR Predicted Transcription Factor Targets 1.0 null organic acid metabolic process GO Biological Process Annotations 2015 1.0 null KLC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85579 AMO1 DepMap CRISPR Gene Dependency 1.0 2.70933 PCDH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10759 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.871827 protoxylem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.19645 FTC238 CCLE Cell Line Gene Expression Profiles 1.0 1.45673 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 digestive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.988032 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCIH2444 CCLE Cell Line Gene CNV Profiles 1.0 1.74745 CTCF_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null procambium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.166914 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9506 IST-SL2 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3229 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21581 UMUC11 DepMap CRISPR Gene Dependency 1.0 2.17402 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.13358 DEPDC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56813 brains GeneRIF Biological Term Annotations 1.0 null ventriculus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.330827 Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21568 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE138019_4_v_6_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100520_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.64748 CTCF_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.864712 POU5F1 ChEA Transcription Factor Targets 1.0 null posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.36562 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16002 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15993 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE213442_1_v_0_kpna2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE234334,GSE234336_1_v_0_zhx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.845277 Acute Myeloid Leukemia_LAML_TCGA-AB-2818-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16907 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 InterPro Predicted Protein Domain Annotations 1.0 null ZBTB12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9522 EBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5359 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18008 myc_20940306_e13dot5_erythroblast_purified_from_liver_gof_mouse_gpl6885_gse18558 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.39759 fruit TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.127046 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.969055 LOVO DepMap CRISPR Gene Dependency 1.0 2.50279 MHHES1 CCLE Cell Line Gene Expression Profiles 1.0 1.35476 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE130690,GSE130692_2_v_0_sirt6_mouse RummaGEO Gene Perturbation Signatures 1.0 null ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2378 TAL1_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GEO COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_3046_KO_Smarcd3_SRP044338 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.40846 SOX2-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null biliary tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.516494 r9 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15904 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles 1.0 1.64478 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.4261 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01651 hemoglobin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.45004 Septofimbrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40687 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21121 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.4645 Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38929 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051368 496100334_PCx_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.17718 lateral septal nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00355 Bacteriocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.22 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2721-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNF225 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48202 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04722 Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JJN-3 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052565 decreased glutamic acid level MGI Mouse Phenotype Associations 2023 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1954 CCLE Cell Line Gene CNV Profiles -1.0 -1.563 Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.119 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15075 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.66813 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052488 NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.106 Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34825 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2746 RCOR1 ENCODE Transcription Factor Targets 1.0 null P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null AMER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18516 KMRC-20 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXP2-21765815-NEURO2A-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32453 Blastodisc TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.607 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1429 LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG Rummagene Transcription Factor Associations 2026 1.0 null COV434 CCLE Cell Line Gene Expression Profiles 1.0 2.30622 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00011 RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9565 Methyl accepting chemotaxis protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.123 ZFX-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE100863,GSE100864_3_v_0_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08435 superficial stratum of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27191 mantle zone of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03618 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838858 Hemorrhage CTD Gene-Disease Associations 1.0 1.17926 endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.058122 NFATC2 JASPAR Predicted Transcription Factor Targets 1.0 null cellular amino acid metabolic process GO Biological Process Annotations 2015 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null JL1 CCLE Cell Line Gene Expression Profiles -1.0 -1.64359 MHH-PREB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041051 TENM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30462 mantle zone of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69162 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66406 lateral septal nucleus, intermediate part, periventricular Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49948 HEC59 CCLE Cell Line Gene Expression Profiles 1.0 1.68525 ChIP_SOX2_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Transcription factor TFIIIB complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.753 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null HOXA10_01_358 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.63068 C3A COSMIC Cell Line Gene Mutation Profiles 1.0 null Hyperglycemia CTD Gene-Disease Associations 1.0 1.02485 Intermediate spinal muscular atrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.527 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC78 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62649 female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cerebral ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.959017 Wholebrain BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.25839 Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-94-8035-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alcoholic hepatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.188 BRG1_DEPLETION_GDS2156_720_mouse_Embryos (maternally depleted) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12886 mantle zone of StrSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00088 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.2558 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null ludlu1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.89 SIX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92357 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC1 ENCODE Transcription Factor Targets 1.0 null PANC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.55402 HS888T CCLE Cell Line Gene Expression Profiles -1.0 -2.12343 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null protozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076177 PMC3348545-NIHMS263168-supplement-3.pdf-188-PURG_PURG Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLF4-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35013 primary auditory cortex (core)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08055 CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40167 olfactory lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.094333 core part of DTg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35244 hepatitis a DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.778204 single-organism cellular process GO Biological Process Annotations 2015 1.0 null H3C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98491 periventricular stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11608 18757432-Table1b GeneSigDB Published Gene Signatures 1.0 null central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10022 Prostate adenocarcinoma_PRAD_TCGA-EJ-5522-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3OO-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30125 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7419 ZNF484 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49019 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34932 occipito-temporal gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.997391 cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.410649 SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null EGFR_druginhibition_82_GSE27638 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.14677 early-onset vitamin B6-dependent epilepsy 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.213 r6 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14997 CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Medial geniculate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.668 fusiform gyrus, right, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86631 r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86552 MDA-MB-330 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03091 paraventricular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03736 UMUC9 DepMap CRISPR Gene Dependency 1.0 4.86543 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74057 Hepatitis CTD Gene-Disease Associations 1.0 1.02522 FGFR3_knockdown_173_GSE41035 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.56555 medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.96318 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 71.9167 Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE208096_1_v_0_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Hindbrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 LK2 DepMap CRISPR Gene Dependency 1.0 5.60735 TPRG1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21875 cellular metabolic process GO Biological Process Annotations 2015 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51822 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05466 snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.63783 erythroid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.170059 gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.270108 sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054668 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8698 SN-56 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.972 Amino acid metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 HDAC6 ENCODE Transcription Factor Targets 1.0 null NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7119 CEBPB-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lateral ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H2BK120ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100544_PCx_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.44861 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.5363 Alanine, aspartate and glutamate metabolism KEGG Pathways 2026 1.0 null MDAMB134VI CCLE Cell Line Gene CNV Profiles 1.0 2.97144 NCIH2110 CCLE Cell Line Gene Expression Profiles 1.0 1.49676 GATA1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null Dorsal tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32858 Bundle sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.052 PMC8410083-elife-65574-fig7-data1.xlsx-KLF10_network-Genes_bound_by_KLF10_in_their_-10_1kb_region_or_differentially_expressed_in_WT_vs_HepKO_hepatocytes_challenged_with_high_sugar_KLF10 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SUIT2 CCLE Cell Line Gene Expression Profiles 1.0 1.40171 Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059948 ELF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8692 PMC8410083-elife-65574-fig7-data1.xlsx-KLF10_network-Unnamed_25_KLF10 Rummagene Transcription Factor Associations 2026 1.0 null MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.18567 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null transaminase activity GO Molecular Function Annotations 2025 1.0 null Myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.288 PAK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13253 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.0793 LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null metaphloem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.178829 dorsal part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27259 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883178 Plastid stroma COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.599 HNRNPUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00588 Kidney Diseases CTD Gene-Disease Associations 1.0 1.19868 limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063228 GSE246053_4_v_3_hnf4a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Coleoptile TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.694 breast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063023 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Six3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.1333 r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18587 Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40932 CTCF ENCODE Transcription Factor Targets 1.0 null H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.69912 Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Perturb_5374_KO_Setdb1_SRP226379 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.79499 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.855204 SNU213 CCLE Cell Line Gene CNV Profiles 1.0 1.34961 GATA1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051794 Gizzard TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.137 Neurotoxicity Syndromes CTD Gene-Disease Associations 1.0 1.01212 GATA1_G1E-ER4_mm9_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null digits BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.22475 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.21258 LS513 CCLE Cell Line Gene Expression Profiles 1.0 1.78503 periventricular stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50031 TAL1 ENCODE Transcription Factor Targets 1.0 null intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.834481 Perturb_9515_KO_Sall4_ERP111723 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.82142 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17453 Lung Neoplasms CTD Gene-Disease Associations 1.0 1.17333 obstructive jaundice DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.739894 m1AD (DM) part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79289 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930798 GSE174751_0_v_1_postn_mouse RummaGEO Gene Perturbation Signatures 1.0 null trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054297 GSE246195,GSE246305_1_v_0_sin3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of isBL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09471 Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7219-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPP1R16B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00698 Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73071 CREB3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20657 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81338 LB771HNC DepMap CRISPR Gene Dependency 1.0 3.28685 ARVCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97977 NCIH2228 CCLE Cell Line Gene Expression Profiles -1.0 -2.6239 degeneration GeneRIF Biological Term Annotations 1.0 null nor GeneRIF Biological Term Annotations 1.0 null FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.2329 ficolin-1-rich granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.636 H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29329 ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066973 TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.490835 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.22085 r2 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23051 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.862627 Gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sporozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.11724 Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.1529 INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.860699 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PSIP1_Deficiency_GDS2883_633_human_T-cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE210377_0_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures 1.0 null blastocysts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.21858 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.74585 Dhori Virus_48Hour_20090954_GSE17400 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.72137 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.76642 Dinoflagellate hypocone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.242 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43391 CTCF_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.974026 mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12886 GSE216538_1_v_3_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.403 cellular process GO Biological Process Annotations 2015 1.0 null Perturb_5169_KO_Ddx5_SRP068412 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.83954 periventricular stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95648 SNU216 CCLE Cell Line Gene CNV Profiles -1.0 -1.48097 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976653 JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.19089 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.262645 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15497 Anterior hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60627 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.04804 intermediate stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0061 spine apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.424745 PDPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20661 Simple lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78735 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE228894_0_v_2_rnmt_mouse RummaGEO Gene Perturbation Signatures 1.0 null neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058454 ANP32E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4171 liver BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.952223 BV-173 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JX-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.176305 periventricular part of StrSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1029 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5011 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2481 seed coat TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.08369 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Liver Failure, Acute CTD Gene-Disease Associations 1.0 1.07057 GSE131161_1_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null leaf lamina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23604 Sapling TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.555 GATA1_G1E-ER4_mm9_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null HLE CCLE Cell Line Gene Expression Profiles 1.0 1.61811 GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46922 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ALAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41751 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.2621 HOXB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60697 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01353 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040678 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.92594 sporangiophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.608527 NQO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80167 FAM104A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47915 Bundle sheath cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.16 CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Spine apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.672 posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.966314 L-Glutamic acid HMDB Metabolites of Enzymes 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.41221 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU61 CCLE Cell Line Gene CNV Profiles -1.0 -1.97248 orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.969014 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.88682 GSE112761,GSE112767_2_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.912625 SMC3-22415368-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KYSE-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Plastid chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.995 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050838 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8922 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1_G1E-ER4_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Foxn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.6458 SPI1-22790984-ERYTHROLEUKEMIA-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.803308 Mantle muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.985 Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45727 GATA1_G1E-ER4_mm9_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null KP2 CCLE Cell Line Gene Expression Profiles -1.0 -2.85041 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.02093 Nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Cardiac muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.47668 KMS26 DepMap CRISPR Gene Dependency 1.0 3.5272 Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30126 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Obstructive jaundice DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05681 GSE120413,GSE120447_3_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05813 SNUC1 CCLE Cell Line Gene CNV Profiles 1.0 1.42063 Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6079 nucleus of the stria medullaris (prethalamic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27488 CAL120 CCLE Cell Line Gene CNV Profiles 1.0 2.06763 ZNF384_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.885424 Hypertrophy CTD Gene-Disease Associations 1.0 1.16001 SMAD1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null A673 CCLE Cell Line Gene Expression Profiles 1.0 2.06809 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.812309 GSE179002_0_v_7_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Riboflavin deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.813 Bronchus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 mantle zone of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13985 YMB1 CCLE Cell Line Gene CNV Profiles 1.0 1.53702 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051241 Lung squamous cell carcinoma_LUSC_TCGA-94-A5I6-01A-21R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37873 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19Q-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAL1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49689 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34252 r1 part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10841 Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1773 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058348 GSE232836_2_v_6_morphine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF700 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12127 496100427_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04979 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885267 GSE112762,GSE112767_1_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.410649 Dentate gyrus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22887 SIN3A ENCODE Transcription Factor Targets 1.0 null COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18162 PU.1-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76214 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9629 NANOG ENCODE Transcription Factor Targets 1.0 null Ornithine carbamoyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.234 cell part GO Cellular Component Annotations 2015 1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1655 Intergeniculate leaflet of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05301 eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1553 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null triangular septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2741 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32741 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.842672 Mesophyll cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.755 blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064707 estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null plastid part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.196999 cytoplasmic vesicle LOCATE Curated Protein Localization Annotations 1.0 null UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07291 tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0995 small molecule metabolic process GO Biological Process Annotations 2015 1.0 null SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27253 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100672_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.61432 ZNF841 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87216 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.425531 hexokinase1 GeneRIF Biological Term Annotations 1.0 null occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.905998 Bacteroid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.449 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.15251 vascular bundle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.271604 laterodorsal tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46809 CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOB1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89679 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01199 Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92177 GSE93674_1_v_0_ezh2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_5021_Mut_Sall4_ERP122174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.4772 r2 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01274 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6925 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32232 membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.00735 ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.90466 SPI1 ChEA Transcription Factor Targets 1.0 null organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.063295 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54545 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.0423 KLF4-19030024-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE169571_3_v_4_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.835664 chloroplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.266042 Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32822 EJM DepMap CRISPR Gene Dependency 1.0 2.28944 viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.160948 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HCC95 CCLE Cell Line Gene CNV Profiles 1.0 1.71749 H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hypocotyl TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.32497 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JAK2_activemutant_178_GSE44961 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.47685 NANOG-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM19 CCLE Cell Line Gene CNV Profiles -1.0 -1.71944 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4659 transaminase GeneRIF Biological Term Annotations 1.0 null dorsal motor nucleus of the vagus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3218 IST-SL2 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 Triangular nucleus of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50991 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null HCFC1 ENCODE Transcription Factor Targets 1.0 null mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49689 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Fruit juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.602 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2613 biosynthetic process GO Biological Process Annotations 2015 1.0 null 18787207-TableS2 GeneSigDB Published Gene Signatures 1.0 null Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.552 H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15326 HN COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 KU1919 CCLE Cell Line Gene Expression Profiles -1.0 -1.56988 primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.02771 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04301 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05513 Endoplasmic reticulum Sec complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.242 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45457 NANOG-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null r6 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19079 organelle envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.133186 AGS COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15884 lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37336 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE112763,GSE112767_4_v_1_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null JHH6 CCLE Cell Line Gene Expression Profiles 1.0 1.60093 superficial stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23211 PMC11711664-41598_2025_85366_MOESM6_ESM.xlsx-AA-METABOLIC_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20701 NCIH1703 CCLE Cell Line Gene CNV Profiles 1.0 1.83606 TCF3/E2A-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1426 NDUFA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26757 smooth endoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.175745 BEN COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POU5F1-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73785 SUPM2 CCLE Cell Line Gene Expression Profiles 1.0 1.91867 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.14644 plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22246 cytoplasmic membrane-bounded vesicle LOCATE Curated Protein Localization Annotations 1.0 null layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15657 GSE102598_1_v_2_nmda_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE112761,GSE112767_4_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null pyridoxal phosphate binding GO Molecular Function Annotations 2015 1.0 null CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.73308 496100291_TCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.05405 PANC-08-13 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98424 LMO2 ChEA Transcription Factor Targets 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null DIXDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55205 CHD1 ENCODE Transcription Factor Targets 1.0 null AMMECR1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8697 FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 71.2289 THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.653 Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06226 posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09281 KASUMI1 DepMap CRISPR Gene Dependency 1.0 3.34205 NCIH810 CCLE Cell Line Gene CNV Profiles -1.0 -1.83835 hilus of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17204 Sarcoma_SARC_TCGA-IE-A3OV-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.4576 parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02135 Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8214 PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-NFAT5_NFAT5 Rummagene Transcription Factor Associations 2026 1.0 null Mesocotyl TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.724 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.124 HCC1395 COSMIC Cell Line Gene Mutation Profiles 1.0 null SOCS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38532 CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4146 NCIH1155 CCLE Cell Line Gene Expression Profiles -1.0 -1.58514 PMC4521181-oncsis201520x8.pdf-149-RREB1_RREB1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21756 496100466_PCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.24219 chr8_37937384_G_C_b38 GTEx eQTL 2025 1.0 2.98089 GSE169713,GSE169715_1_v_2_tert_mouse RummaGEO Gene Perturbation Signatures 1.0 null EMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05884 MON2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74867 carboxylic acid metabolic process GO Biological Process Annotations 2015 1.0 null Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.25566 Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.8071 suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.190957 HCC1500 CCLE Cell Line Gene CNV Profiles 1.0 2.61968 Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPARD ChEA Transcription Factor Targets 1.0 null SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22599 adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05398 cholestasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.59952 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11087094__F3 PFOCR Pathway Figure Associations 2024 1.0 null 496100618_PCx_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.0112 LRR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2517 periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.091 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.861748 COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE149123,GSE149128_1_v_0_cdk7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pyrenoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.63 Metencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32444 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06293 GSE153064,GSE153065_1_v_2_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE138818_1_v_0_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pyridoxamine 5'-phosphate oxidase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 aspartate metabolic process GO Biological Process Annotations 2023 1.0 null Acute myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 HS2ST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69716 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96956 SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Euthyroid sick syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.271 FOXP2 ENCODE Transcription Factor Targets 1.0 null cytosol COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.61883 MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.11864 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.09893 piriform cortex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25352 superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.8645 pyridoxine-dependent epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.840833 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19706 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 4.15499 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_18Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.37932 OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976653 intracellular part GO Cellular Component Annotations 2015 1.0 null ChIP_POU5F1_16518401 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null aspartate biosynthetic process GO Biological Process Annotations 2025 1.0 null HEBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08017 ETS1-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DAN-G COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 SLR25 CCLE Cell Line Gene CNV Profiles -1.0 -1.49784 locus GeneRIF Biological Term Annotations 1.0 null ZFX-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SPI1-22790984-ERYTHROLEUKEMIA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE179002_4_v_7_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null dicarboxylic acid biosynthetic process GO Biological Process Annotations 2025 1.0 null Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01274 DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08052 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cytoplasmic part LOCATE Curated Protein Localization Annotations 1.0 null marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067728 SLU7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10788 gametophyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.742564 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.13358 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE173911,GSE173917_0_v_1_morc3_mouse RummaGEO Gene Perturbation Signatures -1.0 null ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.146 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.107 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01595 Superior colliculus, superficial gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09021 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74784 IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07138 CTCF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4568 PANC1005 DepMap CRISPR Gene Dependency 1.0 3.00906 SW1271 CCLE Cell Line Gene CNV Profiles -1.0 -2.08265 HMV-II COSMIC Cell Line Gene Mutation Profiles 1.0 null L-Aspartic acid HMDB Metabolites of Enzymes 1.0 null proplastid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.844237 Oligospermia CTD Gene-Disease Associations 1.0 1.23993 p2 portion of the parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03006 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.015 GATA1 ENCODE Transcription Factor Targets 1.0 null ehrlich ascites carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.566828 inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33145 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_KLF4_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40167 intermediate stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67945 Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16389 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.936635 Nectar TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.965 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 129.385 SMC3 ENCODE Transcription Factor Targets 1.0 null GSE193685_2_v_3_il11_mouse RummaGEO Gene Perturbation Signatures -1.0 null CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22831 GSE248858_4_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.079238 Hepatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057245 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21756 GSE198165,GSE198166_9_v_11_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69415 PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.076 bundle sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.701489 occipito-temporal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31872 Telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-KD-A5QU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCILY19 CCLE Cell Line Gene CNV Profiles 1.0 1.3623 Childhood spinal muscular atrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.159 lateral parabrachial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.852939 KDM5A ENCODE Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATP13A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06659 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.2956 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 RAD21_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null L3MBTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78113 GSE200687,GSE200688_1_v_0_sox15_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.97928 globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22485 FOXH1-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RUNX1-22343733-PBMC-HUMAN-BONEMARROW ChEA Transcription Factor Targets 2022 1.0 null Cerebellum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H6PD_KO_GDS3195_602_mouse_Skeletal muscle - Soleus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE156907,GSE160237_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.21847 GSE183271_2_v_3_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15751 SIRT6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE199899_4_v_2_diethylnitrosamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE100217_1_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null ENTPD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46569 CoPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95539 Neurobehavioral Manifestations CTD Gene-Disease Associations 1.0 1.165 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97192 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null sirolimus_mus musculus_gpl1261_gse5332 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nectary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.215147 plant ovule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.887133 FERMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45007 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01913 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null atypical GeneRIF Biological Term Annotations 1.0 null RUNX2 JASPAR Predicted Transcription Factor Targets 1.0 null DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09359 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.4031 Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.7947 neuron part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.048666 organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE162739_7_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.330827 dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28439 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.44637 Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07774 EEIG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86131 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.732 Fatty Liver CTD Gene-Disease Associations 1.0 1.44954 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4063 thyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.0949 Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.02435 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08116 POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.842672 EP300-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE57875_1_v_0_hnrnpl_mouse RummaGEO Gene Perturbation Signatures 1.0 null ATP-binding cassette (ABC) transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.673 496100476_TCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.72064 GSE114690_2_v_3_tnfsf14_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9672 Oxalacetic acid HMDB Metabolites of Enzymes 1.0 null HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.958073 neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066331 FOXP2_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SNU761 CCLE Cell Line Gene CNV Profiles -1.0 -1.69541 captopril_mus musculus_gpl1261_gds3683 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null seedling TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306083 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045447 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052063 H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Phosphopantothenoylcysteine decarboxylase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.12 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.957817 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLF4-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9673 Oxoglutaric acid HMDB Metabolites of Enzymes 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12875 frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.080078 Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.501 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null leaf epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.246442 H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null estradiol_mus musculus_gpl4134_gse23241 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058904 ZNF580 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47541 SW1271 CCLE Cell Line Gene Expression Profiles -1.0 -1.76417 Cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976653 superior parietal lobule, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.834566 Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32403 NCIH2172 CCLE Cell Line Gene Expression Profiles 1.0 1.63536 Sarcoma_SARC_TCGA-DX-AB2F-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Cholestasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.143 L-aspartate:2-oxoglutarate aminotransferase activity GO Molecular Function Annotations 2023 1.0 null NUP155 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7521 Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067555 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_35_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 1.22402 NANOG_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.941957 NCIH226 DepMap CRISPR Gene Dependency 1.0 2.429 SW1417 CCLE Cell Line Gene CNV Profiles -1.0 -1.95097 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C6-06A-12R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE196699_2_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.6993 KDM5B-21448134-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.3786 microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36285 anion binding GO Molecular Function Annotations 2015 1.0 null HS255T CCLE Cell Line Gene Expression Profiles 1.0 2.07789 KDM5B-21448134-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28275 olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.103422 NCIH520 CCLE Cell Line Gene CNV Profiles 1.0 1.39408 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22167 BACH1 ENCODE Transcription Factor Targets 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FGFR3_knockdown_34_GDS4454 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.56557 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27253 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2508 ZNF384_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LAMC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21161 Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null erythroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.170059 GSE157049,GSE157051_7_v_1_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 temporal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44174 CCK81 DepMap CRISPR Gene Dependency 1.0 4.19901 Hyperplasia CTD Gene-Disease Associations 1.0 1.17268 basolateral nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.834414 SETDB1_KO_GSE40296_7_mouse_brain (telencephalon) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.552251 SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923784 ovary HPA Tissue Protein Expression Profiles -1.0 -0.846728 Lymph node TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -1.91733 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXP2-21765815-NEURO2A-MOUSE ChEA Transcription Factor Targets 2022 1.0 null DCP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93483 ventral paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68138 Perturb_4945_KO_Rybp/Yaf2/Prc1_SRP247114 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.38085 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Muscle myosin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.553 MEL-JUSO COSMIC Cell Line Gene Mutation Profiles 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.873965 SIRT1_KO_GDS3666_295_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.881383 periventricular stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27847 OCI-AML3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976653 GSE149124,GSE149128_3_v_0_cdk7_mouse RummaGEO Gene Perturbation Signatures 1.0 null oxoacid metabolic process GO Biological Process Annotations 2015 1.0 null blood serum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.707221 CHST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65147 primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23676 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5737 zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15026 telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054963 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22953 Proteinuria CTD Gene-Disease Associations 1.0 1.26886 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0245 YKG-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARS-CoV MA15_Day4_None_GSE49262 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.53629 Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89279 Sarcoma_SARC_TCGA-3B-A9HP-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.129241 Proteasome core complex, alpha-subunit complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.167 HCC70 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Nucleus x Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09651 ZNF384 ENCODE Transcription Factor Targets 1.0 null organelle LOCATE Curated Protein Localization Annotations 1.0 null periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79088 Reye syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 GSE149124,GSE149128_3_v_1_cdk7_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.8684 GYG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83873 whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.357058 MDAMB157 DepMap CRISPR Gene Dependency 1.0 2.24716 transaminase activity GO Molecular Function Annotations 2015 1.0 null mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.59264 SNU182 CCLE Cell Line Gene CNV Profiles -1.0 -1.7868 FOXP2 ChEA Transcription Factor Targets 1.0 null SIRT6 ENCODE Transcription Factor Targets 1.0 null OVTOKO DepMap CRISPR Gene Dependency 1.0 3.90497 GSE118617,GSE118619_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Myxedema DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.281 Superior colliculus, zonal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32403 GRK5 Pathway Commons Protein-Protein Interactions 1.0 null Blood serum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.335 Brain Lower Grade Glioma_LGG_TCGA-HT-7475-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2142 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.41833 aspartate family amino acid biosynthetic process GO Biological Process Annotations 2025 1.0 null SOX13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93574 Reservosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.759 19621087-Table1a GeneSigDB Published Gene Signatures 1.0 null Cytostome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.635 Aminotransferase, class I/classII InterPro Predicted Protein Domain Annotations 1.0 null Bone marrow TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 496100366_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19796 Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56354 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55073 GSE110268_2_v_3_foxd1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC70 COSMIC Cell Line Gene CNV Profiles -1.0 -3.44288 GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100468_PCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.90421 Cell envelope Sec protein transport complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.007 NANOG ChEA Transcription Factor Targets 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ROCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39457 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null methylphenidate_mus musculus_gpl11180_gse33619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28779 RELA JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null WM983B CCLE Cell Line Gene Expression Profiles 1.0 1.50081 HCC1395 DepMap CRISPR Gene Dependency 1.0 2.25855 GSE133213_2_v_3_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48005 ETV4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2134 HT1197 CCLE Cell Line Gene Expression Profiles 1.0 1.65888 GSE130690,GSE130692_1_v_0_sirt6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.56553 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 89.7085 CTCF_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.482038 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0245 DMS-114 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25831 RAD21 ENCODE Transcription Factor Targets 1.0 null CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76514 WSU-DLCL2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976653 COLO792 CCLE Cell Line Gene Expression Profiles 1.0 1.45004 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 megasporangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.890525 ZC3H11A ENCODE Transcription Factor Targets 1.0 null Heart TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cell part LOCATE Curated Protein Localization Annotations 1.0 null shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.131783 GRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58553 GSE162739_4_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H1-0 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42474 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930798 MYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8847 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.277 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59408 496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.80232 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9969 GSE101537_1_v_2_neurog3_mouse RummaGEO Gene Perturbation Signatures -1.0 null inferior occipital gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.83836 r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05919 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.02041 primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.834935 KASUMI1 CCLE Cell Line Gene Expression Profiles 1.0 2.33655 spleen HPA Tissue Protein Expression Profiles -1.0 -0.846728 r3 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01503 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nuclei of the stria terminalis, posterior division, principal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17168 NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE186620_0_v_1_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SW837 CCLE Cell Line Gene Expression Profiles 1.0 1.47116 Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal part of m1A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39634 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SQ-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLF4-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.957998 Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KG1 CCLE Cell Line Gene CNV Profiles 1.0 2.12461 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null blood plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.587228 midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08773 CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE107854_2_v_0_prmt5_mouse RummaGEO Gene Perturbation Signatures 1.0 null pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.56502 CTCF_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bed nuclei of the stria terminalis, posterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10983 transaminase activity GO Molecular Function Annotations 2023 1.0 null SKOV3 DepMap CRISPR Gene Dependency 1.0 2.58987 ZBTB26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50547 central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34993 Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.401 dorsal preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69415 dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65271 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null 18757432-Table1a GeneSigDB Published Gene Signatures 1.0 null Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52665 Fascia adherens COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.562 ZNF410 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.738 periventricular stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17668 GSE150215_1_v_2_etl4_mouse RummaGEO Gene Perturbation Signatures -1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19083 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE246195,GSE246305_4_v_5_sin3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.656 Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.334498 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.232744 TE-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.396087 HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null lateral septal nucleus, intermedio-intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0878 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05677 Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00815 r2 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27028 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24218 RDES CCLE Cell Line Gene Expression Profiles 1.0 2.65491 KDM5B ChEA Transcription Factor Targets 1.0 null CHSA0011 COSMIC Cell Line Gene Mutation Profiles 1.0 null ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.8132 Cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.6323 fruit juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.7146 erythrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.307528 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 Skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ovary GTEx Tissue Gene Expression Profiles 1.0 1.52721 lateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32529 LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79088 ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08435 GPRC5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50798 Lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KLF4 ChEA Transcription Factor Targets 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null Nucleus of the lateral lemniscus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11535 forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053355 SUDHL8 CCLE Cell Line Gene Expression Profiles 1.0 1.42275 DMS114 CCLE Cell Line Gene CNV Profiles 1.0 1.88974 Ciliary pocket membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.78 nucleus of Barrington Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32549 SIGIRR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71598 inorganic GeneRIF Biological Term Annotations 1.0 null NP5 DepMap CRISPR Gene Dependency 1.0 2.6003 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_KLF4_19030024 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Immune system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 transferase activity, transferring nitrogenous groups GO Molecular Function Annotations 2015 1.0 null Brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.810638 cytoplasmic GeneRIF Biological Term Annotations 1.0 null KLKB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21075 EP300-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null VMRCRCW CCLE Cell Line Gene CNV Profiles -1.0 -1.59097 Edema CTD Gene-Disease Associations 1.0 1.29533 786-O Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05466 TEX261 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38809 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null Thylakoid lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.501 OCILY19 DepMap CRISPR Gene Dependency 1.0 8.95012 ARMCX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7084 lateral group of nuclei, right, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.903521 Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WHSC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null INSM1_KO_GDS5066_472_mouse_pituitary gland GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18746 nectar TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.00676 endoplasmic reticulum LOCATE Predicted Protein Localization Annotations 1.0 null retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3501 hnf4a_16714383_e18dot5_liver_lof_mouse_gpl1261_gds1916 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.202659 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Posterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00944 EP300_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null root TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.315135 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52408 PFSK1 DepMap CRISPR Gene Dependency 1.0 2.97756 HC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null SALL4-18804426-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null U2OS CCLE Cell Line Gene Expression Profiles -1.0 -1.72865 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.46548 membrane-bounded vesicle LOCATE Curated Protein Localization Annotations 1.0 null GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Weight Loss CTD Gene-Disease Associations 1.0 1.31867 cytosolic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.37966 bed nucleus of the stria terminalis, laterocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08298 CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ventriculus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.11 TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null heart TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.392309 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.73092 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP1_01_209 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.86685 Chloroplast nucleoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.842 shell of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27774 angular gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.960212 GSE224969,GSE224971_0_v_5_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 44.1384 aspartate biosynthetic process GO Biological Process Annotations 2023 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.53421 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054464 CREBZF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65516 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHLA90 DepMap CRISPR Gene Dependency 1.0 3.40602 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.50167 cytoplasm GO Cellular Component Annotations 2015 1.0 null amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.949927 ZNF341 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8519 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 PATU8988T DepMap CRISPR Gene Dependency 1.0 2.4689 GSE226316_1_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null EFCAB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27801 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32372 Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6793 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041882 chloroplast envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.51694 HCC2185 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.935302 H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null amacrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.314409 temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04319 olfactorybulb BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.1812 GSE145323,GSE145324_1_v_0_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null r10 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03544 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.336 dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08742 superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37956 intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null L-aspartate:2-oxoglutarate aminotransferase activity GO Molecular Function Annotations 2025 1.0 null Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.9433 CTCF_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01274 ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5697 CTCF_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part LOCATE Curated Protein Localization Annotations 1.0 null Glutamate synthase complex (NADPH) COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.196 LATS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4429 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HN CCLE Cell Line Gene CNV Profiles 1.0 1.42548 Leaf axil TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.643 CEBPB-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142684_0_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null DIFI DepMap CRISPR Gene Dependency 1.0 2.44536 RUNX2-24764292-MC3T3-MOUSE ChEA Transcription Factor Targets 2022 1.0 null r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34685 BHLHE40 ENCODE Transcription Factor Targets 1.0 null GSE138019_4_v_5_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE196110_1_v_2_ndrg3_mouse RummaGEO Gene Perturbation Signatures 1.0 null euthyroid sick syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.15666 GSE220520_5_v_7_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE184902_4_v_0_adipor1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03317 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.42082 HCC1500 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34774 mantle zone of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01199 OCIM2 DepMap CRISPR Gene Dependency 1.0 2.89926 GSE112860_3_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2AC21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00805 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22234 GSE173578_3_v_0_atf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE149124,GSE149128_2_v_1_cdk7_mouse RummaGEO Gene Perturbation Signatures 1.0 null plant embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.322779 RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.98365 Marasmus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.411 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00205 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927131 cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06897 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.220152 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49774 OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12479 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PDCD2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46465 Chloroplast stroma COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.65 CTCF_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28144 Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.021 SOX2 ChEA Transcription Factor Targets 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051265 mesophyll TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.474258 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.246 lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25112 Ehrlich ascites carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.928 mantle zone of PThE Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27259 icSARS CoV_0Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.58297 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.7655 GSE224237_1_v_0_resiquimod_mouse RummaGEO Drug Perturbation Signatures -1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null GSE179002_3_v_8_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Rhox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.0381 NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84328 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74879 Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98655 r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94872 striatal septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00088 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18232 OSR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.067 hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.365193 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5609 PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-MYC_MYC Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95089 Arginine biosynthesis KEGG Pathways 2026 1.0 null inferior temporal gyrus, left, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10804 Inflammation CTD Gene-Disease Associations 1.0 1.50043 SIN3B-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE167218_1_v_0_hoxd12_mouse RummaGEO Gene Perturbation Signatures 1.0 null UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984801 SKNMC CCLE Cell Line Gene Expression Profiles 1.0 3.40792 SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984801 ChIP_ZFX_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2836 GSE229978_4_v_1_morphine_mouse RummaGEO Drug Perturbation Signatures 1.0 null r2 liminal central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11399 Tyrosine metabolism KEGG Pathways 2026 1.0 null mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49946 anterior digastric muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3426 dorsal part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69289 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null aspartate metabolic process GO Biological Process Annotations 2025 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10379 SALL4-18804426_ESC-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4264 Pectoral muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.915 KG-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 Lung squamous cell carcinoma_LUSC_TCGA-66-2742-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.266913 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE179036_1_v_0_trim24_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7312 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2170 DepMap CRISPR Gene Dependency 1.0 2.2636 medial parabrachial nucleus,right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54765 UCHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5147 H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SQ1 CCLE Cell Line Gene CNV Profiles -1.0 -2.29057 Testicular Diseases CTD Gene-Disease Associations 1.0 1.03197 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.86344 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 molecular layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10908 GSE163920_1_v_0_sirt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pyridoxal phosphate-dependent transferase InterPro Predicted Protein Domain Annotations 1.0 null GSE184902_4_v_0_adiponectin_mouse RummaGEO Drug Perturbation Signatures -1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles 1.0 1.03378 FOXO3_01_267 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.03092 BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.670739 Adrenocortical carcinoma_ACC_TCGA-OR-A5K5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null vesicle LOCATE Curated Protein Localization Annotations 1.0 null Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.2516 KDM5B ENCODE Transcription Factor Targets 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null RAD21_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52132 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1854 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null Histidine metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.897 GSE61117_0_v_1_trim24_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE193334_1_v_0_six1_mouse RummaGEO Gene Perturbation Signatures -1.0 null chloroplast part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.311478 CAL-120 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052542 CTDK-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.882 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35087 CMAH_KO_GDS4770_420_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32931 SIN3B ChEA Transcription Factor Targets 1.0 null ChIP_SALL4_18804426 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null glucosephosphate dehydrogenase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.231102 Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JIMT1 CCLE Cell Line Gene CNV Profiles 1.0 1.51849 SDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79693 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.115547 Bile duct disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.03 PMC9374162-mmc4.xls-KD_gene_list_heatmap_235_genes-Gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null SW756 COSMIC Cell Line Gene Mutation Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Interrenal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.636 H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE189683_3_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cell projection part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047476 Perturb_5109_OE_Trim66_SRP311833 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.43986 4-aminobutyrate transaminase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.21 r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50199 VASH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57152 HS751T CCLE Cell Line Gene Expression Profiles 1.0 1.97637 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null postmortem GeneRIF Biological Term Annotations 1.0 null Cysteine and methionine metabolism KEGG Pathways 2026 1.0 null Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8701 granule cell layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36964 medial part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04337 Pyridoxal 5'-phosphate HMDB Metabolites of Enzymes 1.0 null CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.65605 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.47284 GSE241701_2_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE248858_4_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null YRDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33436 fusiform gyrus, left, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.949939 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.84501 GSE179002_2_v_6_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZFP14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.7842 DB DepMap CRISPR Gene Dependency 1.0 2.9309 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.046 subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61598 pterigoid muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33663 hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062508 COLO680N CCLE Cell Line Gene CNV Profiles -1.0 -1.56191 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null aspartate biosynthesis HumanCyc Pathways 1.0 null Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8993 HIBADH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83565 segregated GeneRIF Biological Term Annotations 1.0 null Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77948 Phenylalanine, tyrosine and tryptophan biosynthesis KEGG Pathways 2026 1.0 null SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.949492 concordantly GeneRIF Biological Term Annotations 1.0 null Dentate gyrus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38671 dicarboxylic acid biosynthetic process GO Biological Process Annotations 2023 1.0 null Nutritional deficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.312 ITGA2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31226 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null inflorescence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.167342 GSE133213_11_v_3_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null plumule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.328262 Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17263 ZNF384_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Salivary gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SUDHL6 CCLE Cell Line Gene CNV Profiles -1.0 -1.44232 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055721 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4740-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null substantia innominata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13895 anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.978664 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Biliary tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.027 mantle zone of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39634 SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.992502 PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042461 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041561 EZH2 ENCODE Transcription Factor Targets 1.0 null ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 70.6226 COV362 CCLE Cell Line Gene Expression Profiles 1.0 1.83255 bile duct disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.520731 Sec62/Sec63 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.245 Zic1::Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.4212 Motor nucleus of trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27692 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 130.613 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18914 primary motor cortex (area M1, area 4)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.914648 Seed coat TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.083 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.49384 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25203 cell part LOCATE Predicted Protein Localization Annotations 1.0 null NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4068 TCF12 ENCODE Transcription Factor Targets 1.0 null 496100384_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14107 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4033 GSE220520_1_v_7_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null endoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.115878 Fascioliasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24587 Perturb_3162_KO_Smarcd3_SRP044338 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.06717 ZNF143 ENCODE Transcription Factor Targets 1.0 null NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64407 GSE131377_4_v_2_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MFM-223 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 Lung squamous cell carcinoma_LUSC_TCGA-85-8582-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59467 MAZ ENCODE Transcription Factor Targets 1.0 null carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05268 HMCB CCLE Cell Line Gene Expression Profiles -1.0 -1.48423 EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06925 glycerol-3-phosphate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.293 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.938017 sporangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.617796 PFEIFFER CCLE Cell Line Gene CNV Profiles -1.0 -1.38519 Perturb_13094_KD_Gcn5_SRP057021 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organonitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null influenza DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.17896 GSE127790_5_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prethalamic eminence Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27333 protophloem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.173104 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03774 liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.469576 planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00349 BT-483 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 BT483 CCLE Cell Line Gene CNV Profiles 1.0 2.36568 Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.19624 SAP30 ENCODE Transcription Factor Targets 1.0 null gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null superficial stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38671 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Sickle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.713 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.985462 HCC38 DepMap CRISPR Gene Dependency 1.0 20.8811 paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1601 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.7846 MED20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99742 NCIH727 CCLE Cell Line Gene Expression Profiles -1.0 -1.58115 binding GO Molecular Function Annotations 2015 1.0 null GSE145323,GSE145324_1_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_5107_OE_Yy1_SRP281855 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 liver TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.03346 cofactor binding GO Molecular Function Annotations 2015 1.0 null IM-95M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976653 IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.9976 FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.6652 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14367 KMRC2 CCLE Cell Line Gene Expression Profiles -1.0 -1.55053 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.1271 SLC22A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74698 pyrophosphatase GeneRIF Biological Term Annotations 1.0 null cerebellar cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.143471 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.429 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48589 Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DYNLT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39557 seed TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.32132 EW22 DepMap CRISPR Gene Dependency 1.0 2.37406 Cerebral ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.406 H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null gizzard TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.3356 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.79558 GSE214442_0_v_1_pak4_mouse RummaGEO Gene Perturbation Signatures -1.0 null CBX3 ENCODE Transcription Factor Targets 1.0 null GSE179002_4_v_8_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null UBR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15938 SOX4-29892750-EML-MOUSE-BONEMARROW ChEA Transcription Factor Targets 2022 1.0 null CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09825 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 Bronchoalveolar system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 plant reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.114132 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.789796 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18232 CAPAN2 CCLE Cell Line Gene Expression Profiles -1.0 -1.64458 GSE178227_1_v_0_tet1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COPI-coated Golgi to ER transport vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.436 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null lobar GeneRIF Biological Term Annotations 1.0 null Smooth endoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.84 HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976653 primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.956437 HCC1359 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875444 mitochondrion COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.361277 rhombomere 11 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34087 NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976653 CTDSPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11292 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00086 Hypoglycemic coma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.397 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36338 CTB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Spinal nucleus of the trigeminal, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55477 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.994474 encoded GeneRIF Biological Term Annotations 1.0 null BT474 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.623867 GSE112761,GSE112767_2_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TCTN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11735 Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cellular_component GO Cellular Component Annotations 2015 1.0 null FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 105.063 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0507 SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hyperprolinemia type 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.153 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.93267 SLTM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10093 Exocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A8S6-01A-31R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Necrosis CTD Gene-Disease Associations 1.0 1.78052 EP300 ChEA Transcription Factor Targets 1.0 null frontotemporal GeneRIF Biological Term Annotations 1.0 null Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H1703 COSMIC Cell Line Gene CNV Profiles 1.0 2.06473 megagametophyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.933624 cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056802 GSE110440_2_v_0_rad21_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null pallidal septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13777 superficial stratum of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15079 trophozoite TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.242672 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAT8L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17838 alcoholic hepatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.684692 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.13171 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null A431 COSMIC Cell Line Gene Mutation Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism metabolic process GO Biological Process Annotations 2015 1.0 null cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060915 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.298524 Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIC JASPAR Predicted Transcription Factor Targets 1.0 null Phenylalanine metabolism KEGG Pathways 2026 1.0 null Superior colliculus, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08164 GSE169713,GSE169715_3_v_2_tert_mouse RummaGEO Gene Perturbation Signatures 1.0 null floret TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.54812 cotyledon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.389666 ZBTB11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9023 MRPL32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37707 CTCF_MEL cell line_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00011 PcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79186 Glutamate synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.442 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.180339 intermediate isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32626 RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.25858 GSE144115_4_v_3_stag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065029 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.526744 PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Gene_name_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null GSE220520_5_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.105396 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03963 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27165 Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null plastid membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.555973 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838858 GSE119701_0_v_1_phf7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_5161_KO_Trp53_SRP048945 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.67378 Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33911 ETV5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7147 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00017 brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059146 GSE149264,GSE149267_9_v_3_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054379 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.849511 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17607 neuropeptide-S nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6853 TC71 CCLE Cell Line Gene Expression Profiles 1.0 1.46532 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29984 ACAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72127 gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.215922 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28205 SPI1 ENCODE Transcription Factor Targets 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.7727 RCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47132 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5194 HEY DepMap CRISPR Gene Dependency 1.0 3.00307 GSE116894_1_v_0_tle3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05557 chloroplast membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.601487 myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067287 GSE145323,GSE145324_3_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38255 ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2819 TRAPPC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45967 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NCIH322 CCLE Cell Line Gene CNV Profiles -1.0 -1.48411 Forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TestisSeminiferousTubule BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.827138 OVKATE CCLE Cell Line Gene Expression Profiles -1.0 -1.4759 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25703 A_CA_04_2009_4dayMOI-10^6_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.12124 Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM98 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24459 GH3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.699 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52408 alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054559 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 8.72596 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.057802 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FTL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53822 normoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.170059 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.519 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THUMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46398 GSE197564,GSE198512_0_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.34334 INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0314 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040948 r7 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03087 GSE179002_4_v_1_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null LC1SQSF CCLE Cell Line Gene Expression Profiles 1.0 1.78936 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48076 posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61007 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.32404 muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.344818 bladder GTEx Tissue Gene Expression Profiles 1.0 0.847229 GSE63048_11_v_8_morc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null planum temporale, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00217 HCC33 CCLE Cell Line Gene CNV Profiles -1.0 -1.33665 xylem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.36526 496100433_HIP_probable Alzheimer's disease_TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.04234 Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE189683_1_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8793 SNU349 DepMap CRISPR Gene Dependency 1.0 2.44621 fusiform gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09941 decreased glutamine level MGI Mouse Phenotype Associations 2023 1.0 null catalytic activity GO Molecular Function Annotations 2015 1.0 null 496100601_TCx_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.58091 GSE174406_2_v_1_lin28b_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE224237_1_v_2_resiquimod_mouse RummaGEO Drug Perturbation Signatures -1.0 null inferior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.962189 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84328 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81443 hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02828 hippocampus (hippocampal formation)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.914648 glutamicoxaloacetic GeneRIF Biological Term Annotations 1.0 null r7 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38586 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 breast cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071603 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain stem TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Supraoptic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.574 cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00089 FADU CCLE Cell Line Gene CNV Profiles -1.0 -2.37824 MAX ENCODE Transcription Factor Targets 1.0 null CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null