association	dataset	threshold value	standardized value
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91337
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10350897-j_biol-2022-0528-S1.pdf-68-GPBP1L1_GPBP1L1	Rummagene Transcription Factor Associations 2026	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01347
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60902
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.04632
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32542
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4267
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.135
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894807
hsa-miR-3136-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Charcot-Marie-Tooth disease type 4D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.31
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46982
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946848
GSE95826_4_v_1_tcra_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.012
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_24_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43528
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04858
NMC-G1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855219
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07883
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01488
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09478
A-2058 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
YB-54-ET23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.290641
GSE210655_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124410_3_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_170_KO_Cebpd_SRP316336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68386
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53393
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11415
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85855
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60992
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38175
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGF1R_druginhibition_46_GSE14024	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.22545
GSE144443_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968839
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410491
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30185
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12849
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49892
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846665
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7005
RRP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03985
GTEX-P78B-0226-SM-3NB1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88459
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8619
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBGCP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21397
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.060576
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1092	DepMap CRISPR Gene Dependency	1.0	2.45481
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Lung transplant rejection_Trachea_GSE3418	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.10921
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0002
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2122
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31945
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19224
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
blocked	GeneRIF Biological Term Annotations	1.0	null
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62201
GTEX-X8HC-0226-SM-4E3K1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41105
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061136
FOXP2-23625967-PFSK-1-AND-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.44003
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10739
planum polare, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11507
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44502
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58209
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.26343
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65653
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	194.508
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-FL_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26737
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918145
SIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31391
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.886419
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052201
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24218
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23539
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18277965-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50743
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7611
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53352
GTEX-TMZS-0226-SM-3DB9N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37121
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARPP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36834
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.33944
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844861
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.397
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159302
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48863
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96009
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83554
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43049
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mdamb134vi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09231
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887715
ERBB2_knockdown_235_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.9508
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73552
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
PSMB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7255
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.897994
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10328
hsa-miR-302b	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16393
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21104
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7488531-13287_2020_1914_MOESM10_ESM.xlsx-HNF4A_regulated_DEGs_750-Unnamed_1_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987466
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3578
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969494
H3K36me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IB-94-WM88_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203293
RIPK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35393
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17422
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.06036
Perturb_4989_KO_Ythdc1_SRP212677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.61629
regulation of cholesterol biosynthetic process	GO Biological Process Annotations 2025	1.0	null
ranolazine_mus musculus_gpl1261_gse25767	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.41063
hsa-miR-372	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
RAGE_knockout_268_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.71304
CHSA0108	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB11FIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52622
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15219
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11851
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.93133
CHD7	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41271
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16549
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70037
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16146
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27752
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041119
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2181
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
IFNLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36299
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.848258
DENND6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52152
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78567
cfos	GeneRIF Biological Term Annotations	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8663
CHD2	ENCODE Transcription Factor Targets	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.87076
rosiglitazone_mus musculus_gpl8321_gds4021	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T5JC-0526-SM-32PM7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21873
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.48244
intermediate white layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08306
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92725
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51368
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41575
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KURAMOCHI	Achilles Cell Line Gene Essentiality Profiles	1.0	1.25296
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4076-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.913302
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of p2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20636
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842404
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21975
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226114,GSE226116_2_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42948
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2597
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051556
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12712
H3K36me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0855
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.42253
IGF2BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94152
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.26669
GSE77108_5_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11951737-12974_2025_3417_MOESM6_ESM.xlsx-Sheet5-CREB_Signaling_Pathway_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1775
GSE113106_0_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE199606_2_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922235
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ONECUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76787
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
el2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26582
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61143
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34139
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28292
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.9327
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51244
COV644	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.84211
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05274
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98866
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.31029
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01736
GSE213041,GSE241532_1_v_0_tle3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90179
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS34	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34788
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01449
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73874
Perturb_11426_KD_PRMT1_SRP357238	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.80646
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.933237
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846642
GSE160246_0_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CENPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24896
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.64929
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96022
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64058
KDM5B	ENCODE Transcription Factor Targets	1.0	null
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_8_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-1626-SM-3K2AE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10347
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.87957
JHH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82623
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79533
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39234
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57187
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883524
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34523
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23029
PMC7618435-EMS211310-supplement-Table_S1.xlsx-C2-HSC_ELP_NR5A1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1237	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889074
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62149
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10266
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rhombomere 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35084
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2168
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19196
HPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.1574
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06837
GTEX-XUJ4-1926-SM-4BOOV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01625
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832778
thrombocytosis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135514_8_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27741
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941858
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16912
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323003
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04913
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.699
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08641
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-1826-SM-4BRVO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27724
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.02334
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
AD-06-OB47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260377
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04961
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00602
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89637
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03596
NCIH1975	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.20729
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
inner CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04972
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58818
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43989
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67504
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842633
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39902
ARMCX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36355
decreased circulating triglyceride level	IMPC Knockout Mouse Phenotypes	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8337-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41215
RD	DepMap CRISPR Gene Dependency	1.0	3.53658
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15465
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56502
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A855-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885436
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1576
KMS34	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96902
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5834-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19155
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86081
EP300	ChEA Transcription Factor Targets	1.0	null
BAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96201
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Salivary_Gland-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.229007
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80978
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02539
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19658189-TableS5	GeneSigDB Published Gene Signatures	1.0	null
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31379
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63885
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
HCC1419	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17159
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89548
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25288
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201217_3_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_3_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7139
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64571
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29399
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40654
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03436
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.233
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21104
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	2.66017
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882063
PMC6831824-mmc7.csv--IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7048_KO_Dll4_SRP057171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.70234
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16288
GTEX-UJHI-1426-SM-3DB9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849788
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11856
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.84114
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847057
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal zona incerta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34925
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23914
Neoplasms	CTD Gene-Disease Associations	1.0	1.17168
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH889	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90975
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30991
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMUGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09132
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424963
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37363
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZY-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85592
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3351
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.890409
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12247
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95526
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50386
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.72
GSE178255_5_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15565
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866826
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Abetalipoproteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21808
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9569
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.840656
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830753
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824658
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLXIP_01_92	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.77313
786O	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9779
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909201
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-11A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53256
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162276_2_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29379
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2125
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.1294
HC-89-WQ85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268893
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.824855
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13607
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26921
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12108
DE-00-JU18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216733
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0829
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97596
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257893
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0787
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28821
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37402
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.803
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65882
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42368
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4816-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-0326-SM-32QOK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883792
GTEX-XGQ4-2226-SM-4AT4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72579
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207787_1_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sepsis_Hepatic Tissue_GSE1781	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.04333
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX2-35687133-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486867
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33597
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893051
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25575
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04623
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.01474
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XY-0326-SM-46MVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892855
RCC-JF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12808
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.73051
GSE77108_3_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14423
Fat-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	13.5737
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32364
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04131
gpr146	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.09425
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_5760_KO_C9orf72/Tmem173_SRP266242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.60191
Weight Loss	CTD Gene-Disease Associations	1.0	1.17366
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910903
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5453-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.22201
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84434
perinatal necrotizing enterocolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.894179
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21826
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70031
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62098
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30722
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0591
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.11719
Sarcoma_SARC_TCGA-3B-A9HI-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12311
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57874
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043853
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neonate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352227
r5 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09302
r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62187
GSE143643,GSE143644_3_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19671
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4384
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27666
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976205
Thymus-endothelial cell of lymphatic vessel	Tabula Sapiens Gene-Cell Associations	1.0	0.422592
RFX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0139
INTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69022
GTEX-XUW1-2326-SM-4BOO5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37939
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7649-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832537
BAZ1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30742
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04768
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33004
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45501
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831724
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X261-0226-SM-3NMD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07335
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12883
MRPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92275
GRANTA519	CCLE Cell Line Gene Expression Profiles	1.0	1.50798
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268949
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33956
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08547
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39067
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13461
hsa-miR-4695-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K36me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82296
HE-16-PO98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245065
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.4294
AC-86-KF37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342003
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_3251_KD_RBM38_SRP091017	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.66555
GTEX-NFK9-0326-SM-3MJGV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0234
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830129
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8727
rhombomere 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04179
RIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0542
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261076
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0226-SM-4AT4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88524
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06422
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846665
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79169
RFWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39708
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.425312
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.876263
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.82997
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060415
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85723
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07882
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.794
Perturb_1558_KO_Ticam1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.80035
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9427
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28779
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58069
GATA1	ENCODE Transcription Factor Targets	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08741
hsa-miR-625	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05606
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41021
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.26856
decreased hemoglobin content	IMPC Knockout Mouse Phenotypes	1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917343
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31299
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.48068
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85266
GTEX-XXEK-2426-SM-4BRUS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40499
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19989
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06802
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16237
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00193
KE-04-OV29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208761
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1724
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-26b	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03606
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056852
GSE196540,GSE196542_4_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87003
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976317
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830746
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05541
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74771
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-IL10_repressed_LPS_induced-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11391
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.21443
BCL3	ChEA Transcription Factor Targets	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6875
UNC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.267
cop9 signalosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.06246
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9661
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35338
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87314
Perturb_16525_KO_Ahr_SRP318414	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.16321
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC8144624-41598_2021_90212_MOESM2_ESM.xlsx-3_hrs_ps_LPS-Duck_gene_name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35432
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863908
Pons, motor related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05766
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02946
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05579
EZH2	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33012
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94369
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2128
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8127
CEBPB-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43935
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52281
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.93735
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840904
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08222
WM793	CCLE Cell Line Gene CNV Profiles	1.0	1.32751
Perturb_2559_KD_U2AF2_SRP226431	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.8505
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00001
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89974
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUDHL10	CCLE Cell Line Gene Expression Profiles	1.0	1.57693
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933124
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57391
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27051
receptor activity	GO Molecular Function Annotations 2015	1.0	null
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3672
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15073
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.23799
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38665
Perturb_7748_KD_HRSP12_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.43782
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.07813
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.697
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01892
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57171
GTEX-XGQ4-1026-SM-4AT4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12262
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19841
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37328
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36075
Pulmonary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892537
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04365
KLF1	ChEA Transcription Factor Targets	1.0	null
RARG-19884340-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1718
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15328
U266B1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47619
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33073
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65567
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50703
WDR82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56877
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.318109
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32188
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12712
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ooplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
GTEX-RWS6-0526-SM-4GIAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928117
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21343
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28771
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ROCK_INHIBITION_GDS3944_462_mouse_Forebrain astrocytes - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab7_TRIM11-KD-down_genes-Table_7_Down-regulated_genes_in_TRIM11-KD_TRIM11-KD1_Control_overlap_TRIM11-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14346
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04769
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0042
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0265
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20219
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
hsa-miR-193a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89823
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40018
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910903
PMC12634441-41375_2025_2771_MOESM8_ESM.xlsx-ATACseq-Table_S3_Bulk_ATAC-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15074
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15073
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3743
CALR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7739
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05568
SNU16	DepMap CRISPR Gene Dependency	1.0	2.97607
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899152
H2461	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65402
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18351
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93767
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53311
GSE240439_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreas-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	7.96397
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65004
GPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22996
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46937
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52854
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78755
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.919275
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946848
frontal operculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.873826
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957474
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27296
TT	CCLE Cell Line Gene Expression Profiles	1.0	1.49345
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYM1	DepMap CRISPR Gene Dependency	1.0	2.40788
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848637
mRNA_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Perturb_5759_KO_C9orf72_SRP266242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.24213
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29266
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9128
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1299	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36438
GSE206400_1_v_0_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09665
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
GSE148066,GSE157787_8_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.424765
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85224
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25284
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965753
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02911
CB-24-AT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202708
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858082
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.05095
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5047
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985643
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21864
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8083
NCIH510	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20309
GTEX-OXRN-0226-SM-2I5EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07175
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T5JW-1726-SM-3GADN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15082
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21153
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43081
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.35139
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Melanotroph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06925
Perturb_1521_KO_Dad1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.69642
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.306
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44282
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56231
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897943
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_G1E-ER4_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12682
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11243
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07988
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05085
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07076
Prostate adenocarcinoma_PRAD_TCGA-G9-6361-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11546
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.402172
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042344
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.27875
Perturb_1544_KO_Rbck1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.40914
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04404
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4564
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51368
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04421
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48948
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19861
hsa-miR-3591-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2902
EBF1	ENCODE Transcription Factor Targets	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8691
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04293
Thymus-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	2.02598
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1553_KO_Sf3b6_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.23357
GSE215086_0_v_1_batf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC1A	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.57499
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0515
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917984
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95228
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869537
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
Poisoning	CTD Gene-Disease Associations	1.0	1.35792
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76162
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.973044
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888785
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.684853
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09231
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74897
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.51183
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34049
ATP2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49988
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21128
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862396
Perturb_1561_KO_Tlr4_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.05395
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24903
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21203
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12842
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.27687
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7736
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14703
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.274
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30227
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05085
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35926
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27638
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73513
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58294
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35883
GTEX-WEY5-1326-SM-3GILS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948832
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.789039
GATA2_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8452
PMC4629535__F5	PFOCR Pathway Figure Associations 2023	1.0	null
CNPY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38773
STK40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84168
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.946128
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKACA_knockout_266_GSE20984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.57356
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929519
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900372
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.44306
GATA1-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE196117_1_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3793_KD_SNTA1_SRP057613	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.03429
GSE215132_1_v_0_ptpn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	159.992
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4776
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890159
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0002
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23668
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1667
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981926
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.972738
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93655
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1744
Perturb_6902_KD_Hdac5_SRP257918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.61718
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45772
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1463	DepMap CRISPR Gene Dependency	1.0	2.82973
Miyoshi muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14643
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4629535__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.091
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.19264
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1126-SM-3DB7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979534
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37476
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0722
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11851
DANG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46792
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01943
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99055
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3314
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56945
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05076
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60936
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847462
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0396
GSE178255_3_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12609_KO_Ezh2/Jak2_SRP075921	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.18724
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65684
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1_KD_AGO2_ERP014062	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053422
SALL4	ChEA Transcription Factor Targets	1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43191
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09076
hsa-miR-520d-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00148
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85204
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31761
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0021
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC25A38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42891
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941327
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14036
RB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32534
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
ATP5ME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77994
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Smith-Lemli-Opitz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
ERBB2_knockdown_234_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76078
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7437
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21002
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-0926-SM-47JXZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971228
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14221
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.8338
parolfactory gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40228
CEBPB	ENCODE Transcription Factor Targets	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09054
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908918
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846665
ZNF429	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04931
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65687
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111102,GSE111105_1_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13851
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36746
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39335
INTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33066
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843502
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.57144
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VK-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34029
CENPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05935
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45608
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199606_2_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89744
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2497
biological_process	GO Biological Process Annotations 2015	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28122
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
lung	GTEx Tissue Gene Expression Profiles	1.0	0.865993
decreased mean corpuscular hemoglobin concentration	IMPC Knockout Mouse Phenotypes	1.0	null
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30643
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nephrolithiasis_Kidney_GSE10162	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.05387
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.041
LN-405	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.984973
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47228
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
Choriocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04312
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21163
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360782
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42733
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9995
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909863
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_ZFX_17448993	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81464
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57153
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
MHH-CALL-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49451
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28292
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76596
GTEx Ovary 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-4.83709
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5395
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03779
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09174
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.852021
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21499
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	1.5924
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28258
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2012
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26467
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42467
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1831_KO_Irf9_SRP149944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.2218
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21803
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49883
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976222
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79578
Lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59758
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00936
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85796
RH30	DepMap CRISPR Gene Dependency	1.0	3.59843
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65045
hsa-miR-3194-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CD-97-ZV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234874
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930142
hsa-miR-520b	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79395
adrenal gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.41067
NCIH1836	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89096
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35828
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26515
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
rectum	HPA Tissue Gene Expression Profiles	-1.0	-1.24626
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67241
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79871
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60722
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83082
C22orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7588
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7551
MYOD1	ENCODE Transcription Factor Targets	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2599_OE_PTH1R_SRP132981	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.21932
Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.75
intermediate stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05085
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955406
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271182
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3302
PMC6275272-FEB4-8-1977-s006.docx-1-Supplementary_Table_S2_Upregulated_genes_under_MYC_knockdown_in_AMU-ML2_cells_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12894
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92579
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.04722
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00863
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48921
ChIP_STAT3_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965753
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.152
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18391
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23377
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36081
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10181
GTEX-XBED-1326-SM-4AT4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15408
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.902827
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2623
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80391
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00952
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84009
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4347
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55024
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30026
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25755
Lung-lung microvascular endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.330008
GTEX-W5X1-1426-SM-3GIKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08075
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.421
GTEX-TKQ1-0226-SM-33HB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20014
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5ST-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
MTF2	ChEA Transcription Factor Targets	1.0	null
OCIAML3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00425
GATA2	ENCODE Transcription Factor Targets	1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55066
FPGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27672
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31563
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7702
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971364
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02851
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07274
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.940369
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3792_KD_MYC_SRP057613	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.42161
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950008
PPP1R14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00569
knockdown	GeneRIF Biological Term Annotations	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12656
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9351
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.6372
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48405
Perturb_2954_KD_Mll3/Mll4_SRP029581	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4852
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13789
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63923
CCNT2	ENCODE Transcription Factor Targets	1.0	null
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2438
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12712
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03511
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.55646
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	2.97319
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60271
GTEX-XBED-2326-SM-47JYR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42377
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45742
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.46727
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
WT1	ChEA Transcription Factor Targets	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	2.21936
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.858525
Thymus-vein endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	3.86503
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161864,GSE161866_1_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95479
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967624
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64293
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.44745
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973513
ASPRV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52734
F36P	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02427
GTEX-S95S-1326-SM-2XCDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911384
GSE148066,GSE157787_5_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE147943_4_v_6_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08774
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7204122-4623107.f1.docx-6-GABPA_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860216
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.31446
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPU-1526-SM-47JXQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28613
Perturb_1600_KO_Ticam1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.47218
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
17683608-TableS1	GeneSigDB Published Gene Signatures	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04496
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72399
hsa-miR-1297	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7038
rectum_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.955001
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.922215
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896291
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09634
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78587
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLITRK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9333
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888785
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25883
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08806
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05766
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886492
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20603
decreased circulating HDL cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81116
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02671
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	4.36322
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207787_1_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT5A-28732065-J2E-MOUSE-BLOOD	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X638-0226-SM-47JZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03648
Acute Myeloid Leukemia_LAML_TCGA-AB-3001-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254194
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42914
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00987
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12611_Mut_Jak2_SRP075921	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.03375
PMC8144624-41598_2021_90212_MOESM2_ESM.xlsx-3_hrs_ps_LPS-merged_Gene_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-X6-A8C5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29624
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02044
Paranodal junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8416
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18274
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12646
YY1	ENCODE Transcription Factor Targets	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46453
GSE159084_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18925
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865227
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41113
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12986
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86416
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999142
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28604
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47005
GTEX-N7MT-0726-SM-3TW8S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890037
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18603
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.881075
GSE210225_0_v_1_uba6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11266
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6201
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23337
MINO	CCLE Cell Line Gene Expression Profiles	1.0	1.70753
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931311
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6208
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7423
GSE242167_1_v_2_cd40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50321
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Unnamed_1_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WXYG-0926-SM-3NB2O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15865
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07778
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29319
MAFG_02_189	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.69188
hsa-miR-491-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cpeptideinduced	GeneRIF Biological Term Annotations	1.0	null
GSE241031_0_v_4_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
colchicine_homo sapiens_gpl3386_gds1753	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13353
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.971447
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48496
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0557
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26661
Perturb_1517_KO_Ctcf_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44117
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4967
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36257
Lung-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.830802
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932487
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38877
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4822
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.977556
hsa-miR-4530	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15074
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53444
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05652
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
19286929-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69273
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23011
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46003
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09304
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0274
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.68596
tremors	IMPC Knockout Mouse Phenotypes	1.0	null
GSE143643,GSE143644_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34382
Striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23874
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04237
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
OVCA420	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82745
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56891
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1609
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82905
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.85222
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
HS852T	CCLE Cell Line Gene Expression Profiles	1.0	1.64073
OCIAML3	CCLE Cell Line Gene Expression Profiles	1.0	1.73344
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053577
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24297
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84408
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9295
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24529
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40715
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52556
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_5_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-88-VW47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368355
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52829
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5176-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922177
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16122
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22337
gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180797
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11516
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25189
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88461
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965753
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241951
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATP6V0E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32627
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876043
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05964
KBTBD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04525
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58143
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Kidney_GSE9493_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8845
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08583
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9129
PMC9362915-pone.0272017.s003.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.984655
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75912
RARG-19884340-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85246
hsa-miR-4800-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GATA4	ChEA Transcription Factor Targets	1.0	null
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926612
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4474_OE_Smn_SRP258674	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.05308
Penis_Foreskin_Keratinocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.37272
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03044
AM38	Achilles Cell Line Gene Essentiality Profiles	1.0	1.01638
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40909
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95823
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7957
ELF1	ENCODE Transcription Factor Targets	1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-429	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
GD-51-SU60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320731
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9518
VTI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94082
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06586
increased circulating alanine transaminase level	IMPC Knockout Mouse Phenotypes	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87884
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-302c	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
long insular gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860794
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58008
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23941
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OV7	DepMap CRISPR Gene Dependency	1.0	2.83179
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
superior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07808
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06868
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69136
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.0304
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67293
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05492
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.90629
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04415
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08461
Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04496
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
20003503-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.399
LNZ308	Achilles Cell Line Gene Essentiality Profiles	1.0	2.81878
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57874
Perturb_1524_KO_Dhx15_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.6468
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06757
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAMALWA	CCLE Cell Line Gene Expression Profiles	1.0	1.53039
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48159
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62372
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924221
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46797
NR2E3	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40293
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03533
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab5_KDM5C-KD-down_genes-Table_5_Down_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848689
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89482
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
tremors	MGI Mouse Phenotype Associations 2023	1.0	null
Sarcoma_SARC_TCGA-DX-A3LW-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1515_KO_Ciao2b_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.81829
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21926
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16833
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055517
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99733
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87435
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01214
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68064
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054219
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83686
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3776
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13923
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-520a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837611
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.36387
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32292
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32481
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72328
GSE101527_0_v_1_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02954
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08806
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.71355
Cytotrophoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38668
GTEX-T6MO-1726-SM-33HB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08294
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.39853
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.965743
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07461
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888284
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826404
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96772
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68437
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03965
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Perturb_1513_KO_Cd14_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.35205
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75293
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01839
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89919
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77342
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25755
Perturb_1570_KO_Cd14_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.84588
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60785
GTEX-OHPM-0226-SM-3LK61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868804
hsa-miR-26a	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922074
GSE126219_0_v_1_haloperidol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18653
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02502
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28105
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT4-19710469-TH1 cell mouse-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02299
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
OCIM1	CCLE Cell Line Gene Expression Profiles	1.0	1.84425
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845897
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909748
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39571
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.13056
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19843
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum (corpus striatum)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96172
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12254
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-c_GATA2_R361_whole_sample_DEGs-Gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17548
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917066
QF-00-NO42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222918
TAL1	ChEA Transcription Factor Targets	1.0	null
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11476
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17911
decreased circulating triglyceride level	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_13490_KD_Ncor1_ERP132013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15764
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64513
BNIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2349
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825994
Breast Cancer_Mammary Gland Tissue_GSE1872	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.74215
M07E	CCLE Cell Line Gene Expression Profiles	1.0	1.4013
GSE149075_3_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23178
Salivary_Gland-endothelial cell of lymphatic vessel	Tabula Sapiens Gene-Cell Associations	1.0	0.304758
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5995
intermediate periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01857
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
Kidney Chromophobe_KICH_TCGA-KO-8411-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40709
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
SALL4-18804426-XEN-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
GTEX-XQ8I-1426-SM-4BOPW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52249
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ROMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06257
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.835246
BCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04989
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040949
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60228
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49595
irf8_00000000_splenic_cd11bplusgrdash1_hdash2b_gen_background_lof_mouse_gpl6887_gse39228	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.873495
OXSM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65849
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041317
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930819
hsa-miR-4269	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8966
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of alcohol biosynthetic process	GO Biological Process Annotations 2025	1.0	null
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23444
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WA-15-KX40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.463724
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0326-SM-48FES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04579
Perturb_6274_KD_HOXCAS3_SRP158772	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.45857
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00497
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14983
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44647
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94261
Perturb_12604_KO_Cbx3_SRP212056	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.47711
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16511
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30705
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55175
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.2868
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93582
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOVO	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10447
Corticotroph adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
OCI-LY-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95001
JHESOAD1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.49856
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87542
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OV-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-82-PP66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311232
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89278
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02742
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73528
BeWo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887702
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
GTEX-S4Q7-1126-SM-4AD6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83061
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10736
HSC4	CCLE Cell Line Gene CNV Profiles	1.0	1.44349
Acute Myeloid Leukemia_LAML_TCGA-AB-2869-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838073
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40153
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3674
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970851
H3K36me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inner SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927781
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26812
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.85678
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75329
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64076
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14502
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66781
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8652
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06903
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4478
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.930818
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66675
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_168_KO_Itgb3_SRP305656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.83778
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC7041704-JEM_20180649_TableS1.xlsx-IL10_repressed_LPS_induced-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849376
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.889058
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59356
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-200b	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12847870-41419_2025_8402_MOESM5_ESM.xlsx-Supplemental_Table_3-Supplemental_Table_3_Top_250_genes_upregulated_in_L1236_or_L428-_conditioned_THP1-_or_monocyte-derived_macrophages_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09231
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39867
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53448
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4217_OE_Hoxa2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.76322
H4K20me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-2.40384
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76596
GSE104508_0_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP2-23625967-PFSK-1 AND SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O5-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.33431
Perturb_12232_KD_SNRPA1_SRP291357	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.33541
GSE124410_6_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.5514
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nodal receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
RKO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.64445
parahippocampal gyrus, left, bank of the cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839532
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45335
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0041
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32852
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24139
increased spleen weight	IMPC Knockout Mouse Phenotypes	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969494
Perturb_17679_KO_l2LsL_SRP228817	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X88G-0226-SM-4GIE4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04364
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOUCY	CCLE Cell Line Gene Expression Profiles	1.0	1.59529
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51272
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15764
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33315
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882704
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07595
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18401
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	1.56763
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02641
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917877
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68438
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146949_1_v_0_hemgn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1902
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-1426-SM-32PLY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97983
GTEX-NPJ8-0226-SM-48TBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02842
MAZ	ENCODE Transcription Factor Targets	1.0	null
CORL47	DepMap CRISPR Gene Dependency	1.0	2.82567
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23985
Perturb_13188_KO_Rbfox2_SRP216887	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.06882
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97377
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12747
Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02505
membrane	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55188
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35963
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.870966
GTEX-XYKS-1826-SM-4E3JV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878807
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17615
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17574
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85314
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.532
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90445
GTEX-UPK5-2326-SM-3P5Z8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16873
Perturb_1545_KO_Rbx1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.27682
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3934
BATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.482
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44771
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5088
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14799
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2505
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79385
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
CMLT1	CCLE Cell Line Gene Expression Profiles	1.0	1.35404
nes	HPA Cell Line Gene Expression Profiles	-1.0	-0.933656
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39022
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21893
SENP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5584
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E8-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_17379_KD_Pparg_SRP190223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.61226
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157233_2_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55847
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5699
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09685
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95652
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51544
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40005
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26691
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3-1855785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16581
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18572
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A8BV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
placenta_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.1409
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89078
kato-iii cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.82094
hsa-miR-4465	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29087
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32203
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59218
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891598
GTEX-WI4N-1426-SM-3LK7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76501
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
SNUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07931
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040125
SUPT11	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12096
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21109
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1551
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29199
WC-33-YP46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281613
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19301
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09665
STAT3-1855785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39902
GSE81193_3_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39257
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50958
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JA-79-II25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227224
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.64439
GTEX-OHPK-0226-SM-3MJH6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931027
TOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11769
decreased mean corpuscular hemoglobin	IMPC Knockout Mouse Phenotypes	1.0	null
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23578
GTEX-XGQ4-0926-SM-4AT4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60559
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.9801
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5574-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KB-77-BA46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223992
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853277
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XV7Q-1726-SM-4BRUU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35301
HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08038
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06169
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
WC-33-YP46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38372
r7 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05198
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20176
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19344
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15273
GTEX-WY7C-2726-SM-3NB3P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77379
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50468
USF2	ENCODE Transcription Factor Targets	1.0	null
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26469
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00711
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886816
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2108
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03668
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69879
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72256
regulation of sterol biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864407
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15296
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.53157
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18212
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.68688
vincristine_rattus norvegicus_gpl1355_gse19290	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27689
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09952
HIF1A_01_224	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60985
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936675
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57079
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74688
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0219
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18076
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.22894
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866838
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6327
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22707
Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23132
PMC12520974-44161_2025_709_MOESM2_ESM.xlsx-Extended_Data_Fig_4a-Extended_Data_Fig_4a_Marker_genes_used_in_the_heatmap_for_ATF3_4_Capillary_and_Venous_in_non-ischemic_vs_PAD_comparison_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04623
NFE2L2_Mutation_GDS4498_597_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC12372887-sciadv.adx2434_sm.pdf-55-HHEX_HHEX	Rummagene Transcription Factor Associations 2026	1.0	null
increased spleen weight	MGI Mouse Phenotype Associations 2023	1.0	null
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51726
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41974
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
hsa-miR-4533	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CDC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15163
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-a_GATA2_R361_Subclone_4_DEGs-SubGene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1067
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35591
decreased circulating cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU-99A	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29855
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47415
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05395
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897782
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUPB15	CCLE Cell Line Gene Expression Profiles	1.0	1.78761
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857727
STAT4	ChEA Transcription Factor Targets	1.0	null
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5469
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27619
decreased circulating iron level	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976587
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03499
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.22853
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903603
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.956005
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.96086
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.98924
PMC7585942-mmc5.xlsx-RBM10_OE_upregulated-Supplementary_Table_S5_RBM10-mediated_gene_expression_changes_in_BEAS-2B_and_PC9_cells_Cutoff_P_0_05_log2FoldChange_1_KD_knockdown_OE_overexpression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TGFBR2_knockout_296_GSE22989	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52596
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25882
ELK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8175
RCM1	DepMap CRISPR Gene Dependency	1.0	3.18432
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64407
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10494
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990425
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35474
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9835
colon_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00209
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11222
JOPACA1	DepMap CRISPR Gene Dependency	1.0	2.14
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954495
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10727
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	3.95967
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57659
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14324
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.49546
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9383
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cholesterol, total	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73319
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4UY-0226-SM-3K2AP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967109
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased circulating alanine transaminase level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE186112_1_v_0_med23_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74464
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH716	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.53932
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28392
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
SUM 159PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965753
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11761_KO_Arg2_SRP198795	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64229
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01016
SLC7A6OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1276
EN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41063
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARG	ChEA Transcription Factor Targets	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07298
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05206
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30607
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8435
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926877
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28134
MM1S	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23765
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
MOLT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51075
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910903
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.990656
GTEX-OXRN-1426-SM-3LK5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83702
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33077
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13382
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68375
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40278
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-1526-SM-3K2AV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824792
PCI-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QS-0226-SM-3NB1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20209
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303253
SREBP-SCAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.306
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6209
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.51481
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-1.28724
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26877
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	1.47142
PMC4254984__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918323
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27679
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R2-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78967
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83031
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0458
HSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27201
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.02114
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34198
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987198
ZNF624	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76894
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.02092
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10649
GTEX-T2IS-0226-SM-32QPH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14547
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21665
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902574
SB-94-ZA83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321978
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90336
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-LUAD_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06599
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.94052
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.45795
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4	CCLE Cell Line Gene CNV Profiles	1.0	1.80584
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08461
HS944T	Achilles Cell Line Gene Essentiality Profiles	1.0	1.4878
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11364
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23745
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.604
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910903
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21727
ZNF528	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60452
Hyperplasia	CTD Gene-Disease Associations	1.0	1.58421
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-11A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0719
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41S-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11978
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3431-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31483
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04983
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	2.88547
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34857
GSE223008_0_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846665
Lung adenocarcinoma_LUAD_TCGA-50-5930-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFAP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26088
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507849
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00764
H3K36me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11059513-mmc1.xlsx-Supplementary_Table1-Table_S1_The_gene_profile_was_down-regulated_after_HIF1A_was_knocked_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61036
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957063
Perturb_324_KD_BCAP31_SRP320890	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.1072
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5837
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22775
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.962719
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70616
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3443
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853956
decreased mean corpuscular hemoglobin concentration	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_16670_KO_Rfx7_SRP140675	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.41032
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84069
TP53	ChEA Transcription Factor Targets	1.0	null
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PELI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58757
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87389
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0051
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30335
TCF3	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8863
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AKT1_activemutant_216_GSE9484	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.47835
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49729
GSE95685_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.90433
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209601_2_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270341
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZB-16-BR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.419416
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
HCC1500	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77067
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49672
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944471
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11243
GTEX-R55G-2426-SM-2TC5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47714
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09835
JHOM1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11135
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68938
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4811
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62564
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35798
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32114
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09724
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12779
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54821
Perturb_1585_KO_Ly96_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.61315
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210859
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82097
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906741
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15073
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13394
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07781
salivary gland	HPA Tissue Gene Expression Profiles	1.0	0.864432
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49168
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11978
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39377
RS411	Achilles Cell Line Gene Essentiality Profiles	1.0	1.31074
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.827092
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946848
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06874
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.411251
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03413
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29808
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42347
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93536
E2F6	JASPAR Predicted Transcription Factor Targets	1.0	null
IGR39	DepMap CRISPR Gene Dependency	1.0	2.91403
18081427-TableS8	GeneSigDB Published Gene Signatures	1.0	null
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17612
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01885
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_767_mouse_Skin - 1 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79121
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8723
STAT4-19710469-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935301
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11588
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862215
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.478095
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28882
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05796
STAT3	ChEA Transcription Factor Targets	1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.69445
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.49669
GSE213746_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3339_KO_Cns4_SRP310440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.81621
ERBB2_knockdown_237_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.02463
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23094
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17956
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13097
GTEX-XPVG-2726-SM-4B66W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91257
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.15301
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47499
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46398
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3194-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ZNF621	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14315
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.4546
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.15252
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46493
HS852T	DepMap CRISPR Gene Dependency	1.0	23.7857
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842731
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4436
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73448
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.56135
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
YD38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52676
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87175
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
JAK2_knockout_79_GSE26188	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.77059
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2791
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983957
GTEX-XV7Q-2626-SM-4BRVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57897
MHC class II protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ROCK2_knockdown_157_GSE34769	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.66181
M040416	DepMap CRISPR Gene Dependency	1.0	3.6795
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23122
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rhombomere 7	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06705
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27052
Weight Gain	CTD Gene-Disease Associations	1.0	1.05423
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02456
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67392
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875122
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918772
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23721
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2508_KD_U2AF2_SRP226431	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.52191
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14011
MOLP2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0112
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03183
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49338
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8273
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.015
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30071
Lung adenocarcinoma_LUAD_TCGA-44-6144-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1063
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199606_6_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
decreased hemoglobin content	MGI Mouse Phenotype Associations 2023	1.0	null
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856026
GTEX-XQ3S-1326-SM-4BOPQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87282
TDG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49276
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44698
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19554
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42025
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.854966
MEL270	DepMap CRISPR Gene Dependency	1.0	2.98695
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.31901
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69751
ATF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WY7C-2426-SM-3NB2V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03134
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	141.237
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.466
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17567
GTEX-SJXC-0226-SM-2XCDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12328
OCRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23864
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0861
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82539
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5688
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10001
GSE215086_0_v_2_batf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12035
Trachea-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.456258
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07435
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
MARCHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58135
Pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKMES1	CCLE Cell Line Gene CNV Profiles	1.0	1.34985
Perturb_7457_KO_DHX36_SRP120502	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.16757
SERBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
GTEX-Q2AH-1726-SM-3NB2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20277
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95019
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63401
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16846
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18485
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.4425
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64475
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66729
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM-159PT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
CC-03-PW00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268004
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22587
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22104
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84129
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A6K9-06A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10774
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08107
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80991
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2072
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0072
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60697
SNU466	CCLE Cell Line Gene Expression Profiles	1.0	1.40783
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856899
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-2226-SM-3NMBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34005
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8172
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829856
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7428
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870415
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.6581
Vasculature-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	3.36003
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4532
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34179
JK1	CCLE Cell Line Gene Expression Profiles	1.0	1.43511
16357179-Table1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15404
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27456
H3K36me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3188	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148066,GSE157787_2_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5936-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1555_KO_Srp54c_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.79044
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33104
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08919
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33661
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00175
hsa-miR-2113	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85116
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11428309-12920_2024_2011_MOESM1_ESM.pdf-26-PITX1_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890205
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41813
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206967
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49159
GSE201309_5_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98422
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55672
2313287	CCLE Cell Line Gene Expression Profiles	-1.0	-2.59747
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4349-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973856
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GSE140322_3_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30742
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884464
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54949
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196962_4_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.11673
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83946
Influenza_B Cell Lymphocyte_GSE3203	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53018
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.811
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59539
Perturb_13491_KD_Ncor1_ERP132013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.74803
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41118
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867641
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246655
Lung adenocarcinoma_LUAD_TCGA-44-6777-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94595
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAC2A	DepMap CRISPR Gene Dependency	1.0	3.72249
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67595
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999607
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183327,GSE183328_3_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKMEL5	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17036
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21455
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
WA-15-KX40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206621
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79125
GSE178255_2_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MET_knockout_263_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.31189
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4642
ED-91-LY45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320402
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18205
ONS76	DepMap CRISPR Gene Dependency	1.0	4.63185
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72848
tcf12_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.081373
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267744
Lung-endothelial cell of artery	Tabula Sapiens Gene-Cell Associations	1.0	0.0564644
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ME1	CCLE Cell Line Gene Expression Profiles	1.0	1.38595
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.5904
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24218
PCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82878
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D1_1084_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15513
hsa-miR-302e	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
DD-66-VY52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203867
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7983
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39126
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04847
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0621
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906104
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83461
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859899
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.12247
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.04388
myc_20940306_e13dot5_erythroblast_purified_from_liver_gof_mouse_gpl6885_gse18558	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.229317
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.444768
PEO1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1225
GSE157555,GSE157556_5_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWOO-2226-SM-2S1P1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05611
Sarcoma_SARC_TCGA-DX-A1L2-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67354
Ebolavirus(ZEBOV)_5day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74526
GSE246195,GSE246305_1_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130956_2_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19454
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47231
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1226	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846665
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
u698	HPA Cell Line Gene Expression Profiles	-1.0	-1.68688
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56654
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36855
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917021
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.2308
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.258745
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968117
USF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ5-1826-SM-3NB22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03404
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80505
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11602
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27193
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PF382	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45919
ARNT_01_317	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-1.43918
NMB	DepMap CRISPR Gene Dependency	1.0	3.63306
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30582
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16288
hsa-miR-193b	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
D502MG	DepMap CRISPR Gene Dependency	1.0	2.80009
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13284
GSE165689_0_v_1_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930895
TP53-32428506-HUMAN-LIVER-HEPTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263242
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16538
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857356
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193999,GSE194000_4_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XE-69-AT35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358126
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GSE184884_6_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833934
Perturb_1554_KO_Sgms1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.75803
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925058
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41304
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41443
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888495
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41279
ZMIZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71363
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053576
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03763
Perturb_5703_OE_H2Aa/H2Ab1_ERP108769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.8406
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866373
intermediate stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01491
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79168
GSE212299_3_v_0_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38568
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55016
H3K36me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00012
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30875
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08701
H3K36me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AKT1_OE_GDS2308_498_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29368
SH2D3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0654
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25464
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28912
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10322841-41598_2023_38117_MOESM7_ESM.pdf-9-FOXF1_FOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
SUM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70092
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05981
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05058
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66297
Perturb_1551_KO_Rpn2_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.20103
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31717
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02079
katoiii	GeneRIF Biological Term Annotations	1.0	null
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7731-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0238
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05198
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857438
hsa-miR-558	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67732
KMS26	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67727
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904043
GTEX-OIZH-0226-SM-2YUMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78556
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55974
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909201
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.6071
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3532
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056326
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Intermediate reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01107
Acute Myeloid Leukemia_LAML_TCGA-AB-2931-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3084
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843926
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL4-18804426-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2852
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73199
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84395
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051203
Lung-vein endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.473092
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18447
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05766
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21835
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13644
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.969022
GTEX-XV7Q-2326-SM-4BRVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02377
CCDC142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54606
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838177
increased red blood cell distribution width	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13809_KD_Ints11_ERP013418	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.71507
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834291
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37012
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87661
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00175
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.78064
SGTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36451
SMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63859
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5147
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.18089
DSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6551
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09696
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.67411
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7927886-2019_239970_BOUSSAID_SUPPL_TABS2.xlsx-GATA1_targets_-_genesets-Unnamed_3_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838073
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61697
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3646
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236072,GSE236075_2_v_1_ccr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-1126-SM-3NMBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2419
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58887
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52344
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prerubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72395
Perturb_1601_KO_Ticam2_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.70877
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
ARHGAP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03725
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Perturb_960_KO_Psmc4_SRP173487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.2873
PMC6718408-41467_2019_11884_MOESM9_ESM.xlsx-YAP1_RELA_DEGs_mice_human-Human_Gene_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53493
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.997126
Hypertrophy	CTD Gene-Disease Associations	1.0	1.64775
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74467
QF-00-NO42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336078
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09836
GSE86507,GSE86509_7_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chorionic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68686
FOXP2	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47556
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2465
outer SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32185
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LK2	CCLE Cell Line Gene Expression Profiles	-1.0	-3.22587
Perturb_1978_KO_Sarm1_SRP332488	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.78892
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48681
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
A4-FUK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of cholesterol metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.9388
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00616
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7253
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2554
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18827
AXL+SIGLEC6+ dendritic cell_Blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DF-93-BT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312353
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22377
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04858
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.372217
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94011
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02457
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.840315
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04369
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42516
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.18971
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852671
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87084
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.02521
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6255
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81604
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08429
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.166
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64472
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-ddORF6_24Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.03088
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EN	DepMap CRISPR Gene Dependency	1.0	2.37977
Perturb_16393_KO_Barx2_SRP034552	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65402
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6626
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985305
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04591
PMC11059513-mmc4.xlsx-Supplementary_Table_11-Table_S4_62_potential_substrates_of_HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-520c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35398
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.346628
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969494
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65471
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28758
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950683
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
M140325	DepMap CRISPR Gene Dependency	1.0	2.47532
TRMT10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47548
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66439
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28978
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2088
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
breast	GTEx Tissue Gene Expression Profiles	1.0	1.31177
km3	HPA Cell Line Gene Expression Profiles	1.0	0.948188
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33904
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95225
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21581
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58974
chr7_1027767_G_A_b38	GTEx eQTL 2025	1.0	5.16729
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25322
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119564_2_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ULK1_knockout_197_GSE60778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.50774
QF-00-NO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293758
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34442
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2958
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-2126-SM-4JBJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984501
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1208
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2013
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17202
r6 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24633
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25318
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60477
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74948
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44499
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11607
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25485
valproic acid_homo sapiens_gpl6244_gse23909	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00519
Perturb_169_KO_Cebpd_SRP316336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17187
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-3.17852
SEM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38912
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_15734_KO_Kmt2d_SRP058264	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.5755
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2_KD_AGO2_ERP014062	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.12675
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79235
H3K36me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H5-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950906
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270201
chr7_1052008_C_T_b38	GTEx eQTL 2025	1.0	1.97191
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62905
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855604
COL27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84243
H3K36me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nb4	HPA Cell Line Gene Expression Profiles	1.0	1.083
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.83733
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50603
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_12Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.59654
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3678
MSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08882
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.99632
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
17975224-TableS6	GeneSigDB Published Gene Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.854005
Fetal Death	CTD Gene-Disease Associations	1.0	1.16933
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04665
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03638
H3K36me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17415_OE_Gata3_SRP150425	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.96649
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04133
decreased mean corpuscular hemoglobin	MGI Mouse Phenotype Associations 2023	1.0	null
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54886
MOLT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.618
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21755
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11283
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85539
USP6NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14951
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
OCILY19	CCLE Cell Line Gene Expression Profiles	1.0	3.29844
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43052
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998348
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8362
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4908-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90807
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15271
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.34227
KP2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.32537
JM1	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5561
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.90008
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7927886-2019_239970_BOUSSAID_SUPPL_TABS2.xlsx-GATA1_targets_-_genesets-Unnamed_1_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59099
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
ELF5	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06418
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96785
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5710-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77623
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34637
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12549
hsa-miR-302a	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4902-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04404
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876402
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49275
GSE87144_3_v_1_rorc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67025
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Perturb_10774_KD_Csde1_SRP383422	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.74829
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306855
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48556
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08306
Perturb_15041_KO_Klf2/Klf4_SRP095733	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.7147
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07048
rhombomere 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28436
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77829
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.736382
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1181
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56171
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30082
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41779
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21104
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3484
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987287
HOXC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28692
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19102
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
GTEX-QV31-1326-SM-2S1QE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952969
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923402
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55355
inner SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970233
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860459
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-AAQO-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0354
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95107
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67595
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11926
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5396
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3658
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12015
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25755
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09231
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39806
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KINSSHIP syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-gen-Down-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8916
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
Perturb_11215_KO_Gpr151_SRP359303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.5176
GSE156033_1_v_2_sparc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.566192
PMC6642679-NIHMS1529080-supplement-5.xlsx-Sheet1-Supplementary_Table_4_ATF3_target_genes_in_DN2_B_cells_that_are_also_SLE_disease_DEG_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196540,GSE196542_2_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20045
JHOS2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.37068
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63267
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE162276_2_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5758_KO_C9orf72_SRP266242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.51785
Superior colliculus, motor related, deep white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00175
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23497
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
INTS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73296
PRDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13374
RS411	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54137
GTEX-WHPG-0626-SM-3NMBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13369
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95358
SW579	CCLE Cell Line Gene CNV Profiles	1.0	2.41117
GSE192689_0_v_2_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_TCF1-GeneSymbol_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45097
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98676
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14366
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949322
Perturb_7286_KD_HNRNPG_SRP064870	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.36475
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.899339
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07595
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12836
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.05089
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042159
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH1	CCLE Cell Line Gene Expression Profiles	1.0	2.0005
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983228
GATA1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MESP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13206
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14835
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1898
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933173
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.977869
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38871
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935107
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12927
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069075
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04986
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44451
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1349
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.56828
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14615_KO_MTAP_SRP186070	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2195
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5505
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17471
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26303
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40047
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823963
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26882
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.346425
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38045
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14585
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41064
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71274
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13748
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65927
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.55676
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0345
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357674
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.842617
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39718
TZM-bl cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15073
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GIMEN	DepMap CRISPR Gene Dependency	1.0	4.23132
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.976
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36561
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91122
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17921
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18143
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10596
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.21695
SLC11A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34986
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03067
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1519_KO_Cul3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.81539
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19139
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49924
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.25085
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C1GALT1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15462
testis_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.835166
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP5MGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21046
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09829
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	1.82044
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAI2_01_225	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.49439
GSE140322_3_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-KLF1_mod_KLF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80867
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01264
HSD11B1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00463
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46026
Liver Diseases	CTD Gene-Disease Associations	1.0	1.11325
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31571
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14094
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48741
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08672
ERBB2_druginhibition_7_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63272
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846665
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5243-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12809
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863939
KATO-III cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.947
r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1348
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31717
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16744
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.77833
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41982
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56795
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.338
Perturb_1537_KO_Ly96_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.86262
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904192
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.928459
PRDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2738
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213048_1_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
decreased mean corpuscular volume	MGI Mouse Phenotype Associations 2023	1.0	null
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13568
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48535
Perturb_1603_KO_Tlr4_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.51139
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26838
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49693
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2422
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23503
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.78532
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61362
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07765
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25921
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96852
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77499
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPCRs, Other(Mus musculus)	WikiPathways Pathways 2014	1.0	null
KINGS1	DepMap CRISPR Gene Dependency	1.0	6.79863
GTEX-WHWD-0826-SM-3LK6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72391
gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22648
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.91582
TP63	ChEA Transcription Factor Targets	1.0	null
SLITRK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68817
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42939
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.43682
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838718
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23985
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00514
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bewo	HPA Cell Line Gene Expression Profiles	1.0	2.33757
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31316
C32	Achilles Cell Line Gene Essentiality Profiles	1.0	1.34168
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
thrombocytosis	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_5510_KO_Vdr/Med1_SRP282245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC5749161-supp_gad.305813.117_Supplemental_Table_S1.xlsx-CLOCK_ChIP_database-Supplemental_Table_S1_ChIP_seq_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65125
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.12066
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15764
GSE210990,GSE211030_3_v_2_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7444
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07692
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-06A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14746
increased red blood cell distribution width	IMPC Knockout Mouse Phenotypes	1.0	null
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58068
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30755
decreased mean corpuscular volume	IMPC Knockout Mouse Phenotypes	1.0	null
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8762
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.05375
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03577
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23163
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921051
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12016
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41346
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887408
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3792
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00739
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
H1-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82403
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.33944
MHHCALL4	CCLE Cell Line Gene Expression Profiles	1.0	1.71338
Perturb_6763_KO|KD_SERPINE2_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.5604
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50062
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.35808
Pulmonary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54335
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0888
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15478
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69006
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5389
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32238
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40306
Perturb_3327_KO_miR23_SRP092642	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.23173
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95901
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52161
ACSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20771
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00347
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03773
EXTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34479
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	3.44763
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03876
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228842
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76943
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.07403
GTEX-S3XE-1626-SM-3K2AJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944563
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40257
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15763
Lung adenocarcinoma_LUAD_TCGA-73-4676-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45413
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	2.80297
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Unnamed_3_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	2.24721
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23385
AE-88-WQ63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202943
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51607
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906321
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9256
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3781
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892053
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85829
hsa-miR-520e	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GTEX-XOT4-0226-SM-4B66Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13838
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886459
Vasculature-lymphatic endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.052256
SRY	ChEA Transcription Factor Targets	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41018
SRSF3_02_127	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59864
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56742
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897221
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
central subpallium (classic basal ganglia)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3006
PCDHGC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49595
GLIS3_KO_GDS3812_500_mouse_Embryonic pancreas at E15.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05006
Perturb_12610_KD|Mut_Ezh2|Jak2_SRP075921	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.39588
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77466
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16015
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894394
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924097
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12273
hsa-miR-149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849871
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12454715-13555_2025_1471_MOESM1_ESM.pdf-34-HOXA5_HOXA5	Rummagene Transcription Factor Associations 2026	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.25
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31897
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16798
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17864
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66822
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1559_KO_Ticam2_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.13016
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26928
Perturb_3341_OE_miR27_SRP092617	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.87622
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883284
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370088
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4099
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875003
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36728
ZNF791	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05604
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0345
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
HC-38-KI38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212913
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0842
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53087
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71276
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1748
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66118
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.884547
RBPJ	ChEA Transcription Factor Targets	1.0	null
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06582
SSNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35402
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lung	HPA Tissue Gene Expression Profiles	1.0	0.947239
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86784
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pioglitazone_rattus norvegicus_gpl341_gse21329	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4226
FXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13023
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-BRCA_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57471
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72139
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.566568
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87627
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0453
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30723
Perturb_3745_KO_Usp8_SRP301242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2075
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-2026-SM-4AD6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22819
H3K36me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBC1D14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52061
GTEX-QV44-1825-SM-447CF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07516
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SH2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73733
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149264,GSE149267_4_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04477
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58775
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73914
Pancreatic delta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71462
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.10644
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7922
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2557
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924663
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66715
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.438128
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847042
MIH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.951994
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X1-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62894
hsa-miR-200c	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69547
Acute Myeloid Leukemia_LAML_TCGA-AB-2854-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.245
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_17262_OE_Foxj2_SRP368260	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.5875
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.033
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39611
rhombomere 6	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53276
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VN(H5N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.87835
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	3.04771
Odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.40898
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83192
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07892
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09421
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59336
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2767
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11355
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	3.02057
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03709
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66677
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900844
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	1.0	1.69341
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994412
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_13004_KO_Upf2_SRP309261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.75362
H3K36me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1726-SM-3DB9F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993121
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40144
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2541
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pontomedullary hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48477
18081427-TableS7	GeneSigDB Published Gene Signatures	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040764
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19511
Gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
Hypotensive episode_Renal Tissue_GSE2401	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.76611
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4953
GTEX-SE5C-2126-SM-4BRUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16077
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62888
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83057
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
nfe2l2_00000000_neonate_p3_lung_lof_mouse_gpl1261_gse29632	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.009934
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250021
Perturb_1530_KO_Gtf2b_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.57555
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833821
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55136
Perturb_1574_KO_Cul3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.67049
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09784
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
u87	HPA Cell Line Gene Expression Profiles	1.0	1.2879
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26649
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0234
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.97785
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6884
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14983
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
decreased circulating HDL cholesterol level	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825186
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.989891
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.078587
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71462
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4403
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11053
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77662
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.59368
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86454
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE101527_3_v_2_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX11_01_213	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.73754
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05085
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865481
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31717
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50712
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32526
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2023
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33681
Villous cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
hsa-miR-4716-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40815
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.825
Pontine reticular nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2257
hsa-miR-892b	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.702522
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19392
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9894
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853096
Perturb_16697_KO_70L02Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.34551
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8057
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00467
P3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73438
MYOG	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89272
Perturb_13808_KD_Ints1_ERP013418	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.32602
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257149
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046905
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269407
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79007
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92359
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23701
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00226
intermediate stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41668
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-11A-12R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
GTEX-TKQ1-1126-SM-4GIAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14285
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2718
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11416
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NN-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2263
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PRKAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56112
GTEX-W5X1-2626-SM-4LMI8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02993
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18554
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.71521
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48604
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01003
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	1.0	2.04212
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5565-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97653
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90801
COQ10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01904
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22585
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8502
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842294
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919531
Rabies CVS-11_7day-Brain_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.45647
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48244
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE210225_0_v_1_inosine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
G protein-coupled receptor heterodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42649
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.85932
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00382
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3EP-11A-12R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2953
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20161705-Table3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05394
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983323
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042158
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27922
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
decreased circulating iron level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09966
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
decreased circulating cholesterol level	IMPC Knockout Mouse Phenotypes	1.0	null
GSE143643,GSE143644_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040034
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31673
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19176
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38714
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07754
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45058
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20648
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11125
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40497
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3692
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40217
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87309
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05643
HS852T	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
AB-00-IL62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227402
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
GSE166315_2_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958905
RBL1_KO_GDS1932_739_mouse_Neurospheres	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18287
GSE199606_6_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-1926-SM-3GIL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986333
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906321
NALM6	CCLE Cell Line Gene Expression Profiles	1.0	2.10356
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.59569
TAL1	ENCODE Transcription Factor Targets	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.56482
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19213
WT1-20215353-NEPHRON-PROGENITOR-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81677
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17384
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAL1-20566737-PRIMARY-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.6374
hsa-miR-373	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.835647
ZNF43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20004
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11387_OE_OC2_SRP122890	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.64768
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04603
hsa-miR-302d	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.094
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45275
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.186
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957661
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74629
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04311
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35022
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846665
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
U2OS	DepMap CRISPR Gene Dependency	1.0	2.24652
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05173
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26519
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17246
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null