association	dataset	threshold value	standardized value
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2126	DepMap CRISPR Gene Dependency	1.0	2.57064
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9463
GSE210101,GSE210114_11_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
MYD88_Deficiency_GDS2650_652_mouse_LUNG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85128
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKMEL31	CCLE Cell Line Gene Expression Profiles	1.0	1.75683
GSE110268_2_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Diseases	CTD Gene-Disease Associations	1.0	1.02299
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14269
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3320-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11127_KO_Epor_SRP061270	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58195
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30111
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04244
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057589
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27619
Perturb_5706_KO_Abcc8_ERP119268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
hsa-miR-4273	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070032
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.18718
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3292_KD_RORA_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2756_KD_RBMS1_SRP254632	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.87484
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	GO Biological Process Annotations 2025	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.36583
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39188
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.931402
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34885
Perturb_3358_KO_Xbp1_SRP157113	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.02096
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34654
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0232
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.65087
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_4894_KD_ZBTB12_SRP158631	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.42119
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCABER	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S11-DUX4_DiffExprGene-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
cholesterol binding	GO Molecular Function Annotations 2025	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.92674
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13396
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23894
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12696
Perturb_126_KD_Tcf7l2_SRP100171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.9661
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5713_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.89892
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_16833_Mut_Runx3_SRP349093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.95248
stomach	HPA Tissue Protein Expression Profiles	1.0	0.81361
Perturb_2013_KO_Blimp1_SRP061216	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.99294
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11785
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09445
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Caudate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1639
GSE109530,GSE109531_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52158
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846673
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.071
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
PAX5_OE_GDS4978_548_human_L428-PAX5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900288
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13894
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19278
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55765
GSE199606_1_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-1226-SM-4LMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15051
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LOU-NH91	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-450b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-577	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.40613
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35797
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
GTEX-XUZC-1126-SM-4BOPZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12497
hsa-miR-548c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6024-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.184424
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agranular insular area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4785
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55664
Autistic Disorder	CTD Gene-Disease Associations	1.0	2.88009
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central subpallium (classic basal ganglia)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14455
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38434
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90718
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64067
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14412_KO_Cnot6/Cnot6L_SRP285826	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31164
Perturb_14730_KD_MAZ_SRP338457	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_16426_KD_APP_SRP187586	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77815
GSE210101,GSE210114_11_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2275
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35738
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.97453
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.46622
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223008_11_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18242
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996048
Liver hepatocellular carcinoma_LIHC_TCGA-T1-A6J8-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9468
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.405
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38969
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06916
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.217
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00302
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23019
TCF4	ChEA Transcription Factor Targets	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00123
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14963
BGC823	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44155
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26857
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975479
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2846
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.623134
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31506
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907239
abnormal lymph node morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7404
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6543_KO_Pck1_SRP363462	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43285
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847483
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836635
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0118
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47582
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of cellular response to growth factor stimulus	GO Biological Process Annotations 2025	1.0	null
NCIH3122	DepMap CRISPR Gene Dependency	1.0	2.53166
GSE128099,GSE128159_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.698
SAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08844
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217452_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10762
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02073
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00002
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53475
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985904
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.0018
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37215
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.999705
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54152
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18967
MCAD_KO_GDS4546_423_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MCF7_CUDC-907_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00704807
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6479
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973964
chr2_174495517_TGTAG_T_b38	GTEx eQTL 2025	1.0	4.06094
Perturb_17244_KO_Klf3_SRP029447	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.71694
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	1.4816
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45705
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04949
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13568
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.14
GSE207728,GSE207808_2_v_1_c646_human	RummaGEO Drug Perturbation Signatures	1.0	null
DLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42653
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22589
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LB771HNC	DepMap CRISPR Gene Dependency	1.0	3.80804
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-579	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43709
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12262
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06948
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.976901
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-944	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ERBB3_drugactivation_31_GDS4361	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.37178
hsa-miR-3919	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
SKMES1	DepMap CRISPR Gene Dependency	1.0	3.03301
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.03009
MAPK14_knockout_14_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.21929
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930053
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66931
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00224
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-544	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_0_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Dacinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00769626
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965779
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.51296
22RV1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07333
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39189
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.1263
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.21877
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81173
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932863
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43076
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06771
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892111
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28463
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06278
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217763
periventricular stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01354
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880738
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NALM6	CCLE Cell Line Gene Expression Profiles	1.0	1.77029
hsa-miR-539	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07794
GTEX-QCQG-1226-SM-48U23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828828
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56691
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.874
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7007
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-23a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC9314667-Table_1.xlsx-Regulons-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.948046
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57851
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_5_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05255
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983955
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01473
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.65181
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935644
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17779
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	73.6442
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54904
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48248
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.989549
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05792
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
MCF7_Panobinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121561
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943173
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59896
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.877298
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
17975224-TableS6	GeneSigDB Published Gene Signatures	1.0	null
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883357
GTEX-P78B-1126-SM-3P615	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839707
Liver Diseases	CTD Gene-Disease Associations	1.0	1.76309
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7305
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3179	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7401-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.5093
A101D	CCLE Cell Line Gene Expression Profiles	1.0	1.50931
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-1926-SM-4DM6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864473
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70057
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5553-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	1.45554
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3777
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.217
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.21984
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69991
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08392
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.414164
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850337
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00505
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PKBalpha_KO_GDS1784_196_mouse_Embryonic fibroblasts (MEFs) - 24h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
18321301-Table2c	GeneSigDB Published Gene Signatures	1.0	null
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
irinotecan_rattus norvegicus_gpl1355_gds3466	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991245
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.49545
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-3_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053623
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.0113
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920274
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901841
MTA3	ENCODE Transcription Factor Targets	1.0	null
CD1C-CD141- dendritic cell_Blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057445
SNU869	DepMap CRISPR Gene Dependency	1.0	2.19739
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03986
Perturb_16935_KD_SOX2_SRP286421	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
A-CA-04-2009(H1N1)_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.40477
enlarged lymph nodes	MGI Mouse Phenotype Associations 2023	1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.977962
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2145
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991597
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82358
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.19607
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837981
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63398
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.44007
Poisoning	CTD Gene-Disease Associations	1.0	1.29781
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88778
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-125a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
enlarged lymph nodes	IMPC Knockout Mouse Phenotypes	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82969
SARS-CoV MA15_Day7-C57BL6_None_GSE51386	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.24748
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2GZ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5606034__F5	PFOCR Pathway Figure Associations 2023	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAK-901_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.015114
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.3671
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3152-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92602
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_118_KD_Fto_SRP314220	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04113
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894144
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30197
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49492
hsa-miR-548k	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23491
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76661
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dexamethasone_mus musculus_gpl6105_gse44208	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0915
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29161
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55442
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186483_1_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10644
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964347
hsa-miR-509-3-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.77073
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09586
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62545
Perturb_3294_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.47502
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11188
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07822
PSPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44816
Mesothelioma_MESO_TCGA-TS-A7OY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16393_KO_Barx2_SRP034552	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25791
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10483
TTC549	DepMap CRISPR Gene Dependency	1.0	2.02793
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZW-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
perilemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00408
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56661
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04651
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.945461
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A551-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26299
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67802
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	1.0	1.4218
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18346
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13346
PMC6293073-LSA-2018-00153_TableS3.xlsx-A_KD_Tr_1_3_genes-30_genes_upregulated_upon_knockdown_of_Tr_1_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03655
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A689-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37573
C8166	DepMap CRISPR Gene Dependency	1.0	3.20988
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2115	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2374
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23258
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06214
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165334_3_v_1_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16830_KO_Cldn18_SRP096968	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04074
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZQ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_4_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2585_OE_ROR2_SRP065310	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.79396
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63733
TAL1	ChEA Transcription Factor Targets	1.0	null
PMC5316868__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE127916_1_v_2_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58724
Perturb_12901_KD_ZBP1_SRP298473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Naive CD8+ T cell_Peripheral blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCI30	DepMap CRISPR Gene Dependency	1.0	2.39694
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18025
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07233
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lysosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32833
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21217
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
Vacuolar lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10592962-media-4.xlsx-OC2_genes-gene_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835335
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34604
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.32674
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_6438_KD_BAT1_SRP191579	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903951
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34486
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4628
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24008
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09017
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUCCT1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-657	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
SMC3	ENCODE Transcription Factor Targets	1.0	null
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47728
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1793	CCLE Cell Line Gene CNV Profiles	1.0	1.6708
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958543
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.328
HES3_KD_GSE64449_187_mouse_Min6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158853_0_v_1_hmgcs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855526
GSE137653_4_v_0_siglecf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02101
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02432
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12914
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08219
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914906
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.5975
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MONO-MAC-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.918597
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0026
PMC7204122-4623107.f1.docx-6-GABPA_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07222
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75237
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01268
Prader-Willi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
GTEX-RU1J-0526-SM-46MUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16127
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18888
GATA1_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826848
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.215
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.27346
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27978
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934783
TP53	ChEA Transcription Factor Targets	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13568
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.85261
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34986
Perturb_1996_KD_Sun1/Sun2_SRP354599	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.40394
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71062
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUPT11	CCLE Cell Line Gene Expression Profiles	1.0	1.71782
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824194
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43182
CCAR2_02_146	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66482
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965427
hsa-miR-640	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.39892
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7422-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19167
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.1341
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129241_1_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927427
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89262
Perturb_6419_KD_PTPRN_SRP322005	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
retina	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29131
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73599
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_11_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ruminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028577
SW948	DepMap CRISPR Gene Dependency	1.0	2.00282
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052781
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884212
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1442
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23464
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MERO82	DepMap CRISPR Gene Dependency	1.0	5.75475
GATA1	ChEA Transcription Factor Targets	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.053321
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79741
Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122509,GSE122513_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111881_0_v_1_znf768_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular response to starvation	GO Biological Process Annotations 2025	1.0	null
EB2	CCLE Cell Line Gene Expression Profiles	1.0	1.35547
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.75
abnormal kidney morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NIHOVCAR3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.89686
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5434
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00341
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27898
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.717
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14642
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30744
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02126
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04463
hsa-miR-3607-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23243
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44379
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular response to alcohol	GO Biological Process Annotations 2025	1.0	null
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06666
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39413
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSS	CCLE Cell Line Gene Expression Profiles	1.0	2.22926
MCF7_Givinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00883322
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7428-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung Diseases	CTD Gene-Disease Associations	1.0	1.23616
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05995
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-A71P-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.49787
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_1_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.30635
PMC5316868__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1011
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7746
HEPA 1-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852163
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-1526-SM-3LK7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68936
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053471
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03151
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26637
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42172
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32913
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0162
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10792
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051437
PMC6172027-elife-38795-fig2-data2.xlsx-XBP1_RNASeq_only-Gene_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13431_KO_Hsf1_SRP263204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.12551
lateropallial prepiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00268
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.65316
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19S-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Abexinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0087201
PMC4823830-ncomms11171-s2.xlsx-GATA3_upregulated_genes-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.108219
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.40489
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.59333
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10407
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	2.22133
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35779
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.4383
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41184
wm115	HPA Cell Line Gene Expression Profiles	1.0	1.28972
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13316
OVCA433	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42186
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5817105-thnov08p0972s2.xls-SIX3_LSD1-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885369
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55172
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pulmonary artery smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
Fatty Liver	CTD Gene-Disease Associations	1.0	1.60617
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TOV112D	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01622
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14641
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.41721
Lytic vacuole membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15903
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44121
GTEX-Q734-1026-SM-48U16	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938574
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893691
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28322
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16366
19036130-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13328
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
testosterone_mus musculus_gpl1261_gse17553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948347
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496874
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265038
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	2.33034
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03532
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.93781
hsa-miR-4766-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.969964
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07233
cellular process	GO Biological Process Annotations 2015	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02702
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21882
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051407
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82328
Perturb_11242_KO_Sirt6_SRP190930	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.05218
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06024
Adenoma_Adrenal gland_GSE8514	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.58595
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84448
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13642
GATA1	ENCODE Transcription Factor Targets	1.0	null
Cerebral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97178
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12898
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5348
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CORL47	DepMap CRISPR Gene Dependency	1.0	4.74696
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877015
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914056
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AZ521	CCLE Cell Line Gene Expression Profiles	1.0	2.58974
GTEX-T5JC-1226-SM-4DM7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840225
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65163
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998323
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
response to cholesterol	GO Biological Process Annotations 2025	1.0	null
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0464
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
c16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7898
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70169
Lung squamous cell carcinoma_LUSC_TCGA-77-8154-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44633
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00605
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3638
KNS42	DepMap CRISPR Gene Dependency	1.0	2.66799
CTR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8444
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06981
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.28177
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	2.52257
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_7_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1976	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
GSE148066,GSE157787_2_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	4.60272
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.930848
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30265
MYC	ENCODE Transcription Factor Targets	1.0	null
TYKNU	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12724
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06515
Inflammation	CTD Gene-Disease Associations	1.0	1.82884
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18541
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01161
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A44A-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-540-PROX1_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070178
CUX1	ENCODE Transcription Factor Targets	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	1.79582
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.696219
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5771
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61904
JHOM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70765
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3946
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23975
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.901294
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.42859
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67594
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12952
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.54178
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45536
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05347
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43723
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14409
striatum (corpus striatum)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39926
subpallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96778
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7CZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23696
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186483_6_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MITF_01_24	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.98602
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38038
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07374
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131887_1_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-223	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9912
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17856
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.5438
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8261-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU878	CCLE Cell Line Gene CNV Profiles	1.0	1.94279
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.19542
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953814
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864889
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.545481
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33939
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6558
Perturb_15726_KO_Il1rl1_SRP274117	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.48632
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19638
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11555
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59365
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967716
HEC1A	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.58756
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Fetal Death	CTD Gene-Disease Associations	1.0	1.60547
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74163
PMC11133462-41467_2024_47218_MOESM5_ESM.xlsx-IL-10_SBNO2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28333
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840283
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046307
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
NCIH146	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49066
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881529
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32511
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57547
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE179031_3_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07656
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2846
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.25245
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.5917
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
nfe2l2_23639809_whole_esophagus_lof_mouse_gpl7202_gse39629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.148306
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91869
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.0204
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9823
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4642	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981129
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15369
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA4_KO_GDS3486_483_mouse_jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7J9-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAG3_Mutation (R225Q)_GSE4067_390_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.984103
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QGP1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.4942
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89551
Substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
Weight Loss	CTD Gene-Disease Associations	1.0	1.5123
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07952
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051081
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38805
mantle zone of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00268
PHF8	ENCODE Transcription Factor Targets	1.0	null
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9824
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01322
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20933
Perturb_17819_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.29734
Perturb_9788_KO_Hif1a_ERP133576	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.52988
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59152
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5566_KO_Sorbs2_SRP221026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96958
Hypoxia_Astrocyte_GSE4483	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.579728
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1921
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952446
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33374
Perturb_16442_KD_IL13RA2_SRP314695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.0132
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.74963
MCF7_M344_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00783491
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neurological system process	GO Biological Process Annotations 2015	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0852
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.816968
LPS510	DepMap CRISPR Gene Dependency	1.0	4.47269
KDM5B	ENCODE Transcription Factor Targets	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12262
GTEX-RTLS-1226-SM-46MUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989515
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50724
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PSMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57071
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07727
hsa-miR-203	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
Perturb_11226_KD_Mafg_SRP165897	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.90239
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
L540	CCLE Cell Line Gene CNV Profiles	1.0	1.65857
Perturb_11592_KD_CASP4_SRP345007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.71522
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66331
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039297
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7286
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833276
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47162
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_14123_KD_Fus_SRP182046	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93991
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMPK gamma-3_KO_GDS1938_163_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.875018
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39059
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21825
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17823
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3789
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31254
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65372
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	202.373
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37135
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-559	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051224
Perturb_14947_KD_Parp1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.72858
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Hypnozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3653	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07168
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
T98G	CCLE Cell Line Gene CNV Profiles	1.0	2.00797
Perturb_3350_KO_miR23~27~24_SRP158259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.35672
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.25565
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82626
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.59404
Perturb_11853_KO_Gdf2/Bmp10_ERP128742	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.39908
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52744
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11799
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.92904
hsa-miR-3677-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2005
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56615
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052599
VPS45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06878
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3425
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988971
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15218
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20775
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95624
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09353
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.953057
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23439
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-HSLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876141
SUM229PE	DepMap CRISPR Gene Dependency	1.0	3.36595
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903224
GDM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.8459
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
19286929-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25063
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8991
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828064
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00611
GSE174383_1_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21783
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33815
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847965
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5515
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50676
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02001
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02215
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.73277
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_2_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65031
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832295
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	2.53908
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78441
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63773
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_949_KO_Bhlhe40|Bhlhe41_SRP216680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.5552
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5104-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55368
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44936
Small_Intestine-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.680926
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7925689-41467_2021_21687_MOESM10_ESM.xlsx-A_HIF1A-Unnamed_8_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910551
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Entinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120765
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-LUAD_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837276
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1787_KO_Irf8_SRP265303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82355
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38306
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_32_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
lysosomal membrane	GO Cellular Component Annotations 2025	1.0	null
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11762
LK2	CCLE Cell Line Gene Expression Profiles	1.0	1.53554
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE212487,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982597
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4174-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal seminal vesicle morphology	IMPC Knockout Mouse Phenotypes	1.0	null
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.01771
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10301
YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0651
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1	ChEA Transcription Factor Targets	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897937
molecular_function	GO Molecular Function Annotations 2015	1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	2.75386
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.852184
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16523
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929099
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A264-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00498
786-0	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99891
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.978896
STAT5A	ChEA Transcription Factor Targets	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.53989
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075857
MYCN_01_296	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.64296
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
HEC59	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65901
GTEX-U8XE-1826-SM-4E3HV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862276
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28192
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882075
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	1.50039
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4002
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99056
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
TAL1-20566737-PRIMARY-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11855
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15991
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A172	DepMap CRISPR Gene Dependency	1.0	3.13459
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01057
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18541
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166308_1_v_0_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02908
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SOCS3_KO_GDS3149_297_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3622b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-miR-632	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059066
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43832
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917284
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846104
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterus	GTEx Tissue Gene Expression Profiles	-1.0	-0.83442
hsa-miR-4539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75057
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49945
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52729
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827504
PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_UP_2_5-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS939T	CCLE Cell Line Gene Expression Profiles	1.0	1.38505
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GSE116299_4_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151364,GSE151366_1_v_0_taf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149075_6_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03268
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-1126-SM-4KKZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14303
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
FOXO1_KO_GSE46025_480_mouse_CD8 T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SH-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06132
cognition	GO Biological Process Annotations 2015	1.0	null
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91087
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18387200-Genes	GeneSigDB Published Gene Signatures	1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19978
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985672
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77273
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.991142
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Large_Intestine-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	5.0052
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11494_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.31887
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KNS60	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24216
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52552
GPR137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52941
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5606034__F4	PFOCR Pathway Figure Associations 2024	1.0	null
CHK2_KD_GSE54268_668_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93656
SP2	ENCODE Transcription Factor Targets	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
trachea	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48784
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03164
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18733
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.21877
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160246_9_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0241749
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92123
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21208
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAPK14_KO_GDS2693_535_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89339
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35786
22RV1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2038
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.9319
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08505
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26346
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5673_KO_Rbfox1/Rbfox2_SRP151185	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43099
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	2.46766
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5413
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.29295
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04949
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824454
GSE131161_3_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2574
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
D542MG	DepMap CRISPR Gene Dependency	1.0	2.13923
valproic acid_homo sapiens_gpl570_gse14973	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLF2_02_29	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63743
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.02716
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
NRDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29573
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04845
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07685
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054804
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE223008_4_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10543
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.863222
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46622
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7511
hsa-miR-3148	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
MBD4	ENCODE Transcription Factor Targets	1.0	null
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66329
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.59991
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855788
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_947_KO_Vdr_SRP176410	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.52598
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901105
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
Perturb_4500_KO_zc3h12a_DRP003625	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.332
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-548l	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63234
hsa-miR-548a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94997
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9864
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00942
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.5612
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Quisinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00864035
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.09948
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16201
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042353
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833276
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4433	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4161-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19947
GTEx Lung 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	10.8042
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908525
WHSC1	ENCODE Transcription Factor Targets	1.0	null
ATM_KD_GSE54268_663_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06234
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24107
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00624
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.319
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13776
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	GO Biological Process Annotations 2023	1.0	null
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.0503
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913408
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22077
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21871
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
CDK8_knockdown_147_GSE32108	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.71871
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912243
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061005
SARS-CoV MA15_Day4-C57BL6_None_GSE51386	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58594
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8963
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ficolin-1-rich granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4700-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.40859
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946529
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7567
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.21877
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.6751
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08903
RAB3A_KO_GDS2482_706_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914906
PMC9882185-media-2.xlsx-Rbm12-specific_B2-AR_targets-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.949663
GSE130475_1_v_2_thpo_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.62728
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82504
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_GSEA_state_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40463
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158815_5_v_0_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833276
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.9419
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19895
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3470785-NIHMS377161-supplement-14.pdf-481-ZNF708_ZNF708	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEx Nerve 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	8.63112
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09898
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09278
IRF6_KO_GDS2359_126_mouse_skin E17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.36768
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44605
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02249
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX5	ChEA Transcription Factor Targets	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56055
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31147
MXI1	ENCODE Transcription Factor Targets	1.0	null
Psmb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-580	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941256
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cortical subplate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15889
disease	GWASdb SNP-Disease Associations	1.0	0.024501
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.57404
vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127970_1_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21422
NFATC2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE228413_4_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68465
SP4	ENCODE Transcription Factor Targets	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PC14	CCLE Cell Line Gene CNV Profiles	1.0	1.89806
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BICR10	DepMap CRISPR Gene Dependency	1.0	2.32537
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT-549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865475
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00203
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0394
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.825
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835576
19377508-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905263
SARS-CoV NSP16_Day2_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.4071
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64101
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	DepMap CRISPR Gene Dependency	1.0	4.02287
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0851
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.854379
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864149
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_upregulated-Genes_upregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_15734_KO_Kmt2d_SRP058264	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.47571
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.833831
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41122
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4470	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832918
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53778
SNU840	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63846
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19816
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04354
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36511
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05069
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6447_OE|KD_EGFR|TRIM24_SRP100743	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35949
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12262
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MES-1	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9203
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43304
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039329
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999294
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4802-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_4_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autism	DisGeNET Gene-Disease Associations	1.0	null
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17876
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.29626
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6983
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53899
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878492
small seminal vesicle	MGI Mouse Phenotype Associations 2023	1.0	null
regulation of BMP signaling pathway	GO Biological Process Annotations 2023	1.0	null
RD	CCLE Cell Line Gene CNV Profiles	1.0	1.52649
GTEX-RWS6-0726-SM-47JXI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94303
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39946
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37193
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32783
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68456
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49118
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00841
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03275
CBX8	ENCODE Transcription Factor Targets	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4876
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-23c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
ATM_knockout_74_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.11703
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	1.0	1.44462
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuronal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
KDM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48548
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075205
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48552
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28613
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
tongue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
MYOG	ENCODE Transcription Factor Targets	1.0	null
enlarged kidney	IMPC Knockout Mouse Phenotypes	1.0	null
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62967
GSE192663_1_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3673
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-451b	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50168
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881895
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10416
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.10295
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-2116	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
GSE186112_1_v_0_med23_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the ear	GWASdb SNP-Phenotype Associations	1.0	0.296809
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53187
GTEX-T2IS-0926-SM-4DM5B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865969
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.574
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_6_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174383_4_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04266
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26444
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199606_2_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04011
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199606_5_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03578
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105159
MFE280	DepMap CRISPR Gene Dependency	1.0	2.48175
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE147240_3_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54181
hsa-miR-4418	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
ROGDI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02331
GSE119564_2_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	1.0	3.02583
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.869778
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7979
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69528
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PKCA_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
CAOV4	DepMap CRISPR Gene Dependency	1.0	2.09711
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16728_Mut_Zfp36_SRP052881	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.81121
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5332-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43938
single-organism process	GO Biological Process Annotations 2015	1.0	null
Whipple's Disease_macrophage_GSE16180	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.369
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Leber congenital amaurosis_Retina_GSE3249	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.30426
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARB-27405468-CHIP-SEQ-BRAIN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4330	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
U937	CCLE Cell Line Gene CNV Profiles	1.0	1.36354
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.08975
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44249
valproic acid_mus musculus_gpl6246_gse23957	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5339
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11603
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.67113
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47798
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999511
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948156
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32611
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052503
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	1.36922
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.897871
Proteinuria	CTD Gene-Disease Associations	1.0	1.20328
small seminal vesicle	IMPC Knockout Mouse Phenotypes	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-495	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4762-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
hsa-miR-4688	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-Q2AG-1226-SM-4GICA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900616
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918208
RCOR1	ENCODE Transcription Factor Targets	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4744	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TRIM28	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40612
GSE137653_2_v_3_siglecf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62038
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UTP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67038
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-2467-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
periventricular stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52986
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908773
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-23b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orphan GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422673
Leydig cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0974
hsa-miR-548d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Agranular insular area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99092
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896773
GSE223008_0_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.969731
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32617
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10476
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71225
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4451
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7000_KO_Acadl/Acadvl_SRP323582	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.1385
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23013
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01905
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4498_KO_Hnf4g_SRP139365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129858,GSE129859_1_v_3_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46153
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5652
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843169
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43413
PMC12956708-DataSheet1.xlsx-Supplementary_Table_7-Supplementary_Table_6_The_DEGs_from_high_altitude_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36266
GATOR1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.444
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41641
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61871
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	3.23192
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64842
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218669
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943038
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941342
hsa-miR-3143	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC16A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66564
BACH1	ENCODE Transcription Factor Targets	1.0	null
Odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25934
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87469
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845538
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864544
NCI-H2066	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SNOS-0826-SM-4DM5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28003
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.58221
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838561
Striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12287
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	231.298
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1887
Perturb_17768_KO_Rbm24_SRP268577	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.54113
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16103
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4753-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	2.21529
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.58678
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_153_KD_Pparg_SRP319128	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8410861-41467_2021_25544_MOESM32_ESM.xlsx-MCR-MCR_cells_-_DGE_iGCA_testis_vs_adult_testis_from_GSE112013_and_GSE124263_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975479
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04146
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27947
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	137.135
TAF7	ENCODE Transcription Factor Targets	1.0	null
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	3.38445
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885725
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879345
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936241
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855613
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.52865
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917989
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970929
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19289
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.682187
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22547
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59512
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90078
establishment of localization	GO Biological Process Annotations 2015	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82425
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1003
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967537
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07799
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876823
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03234
Glans penis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
MCF7_Trichostatin A_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0105408
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08795
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77527
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_224_KD_YBX3_SRP289565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.0265
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04172
mRNA_YY1_22210892	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053133
Perturb_5926_KD_LOXL2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.20083
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30474
HCC364	Achilles Cell Line Gene Essentiality Profiles	1.0	1.94434
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04289
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.046
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2253
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99603
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01164
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58336
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.05423
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKMES1	CCLE Cell Line Gene CNV Profiles	1.0	1.80531
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35603
hsa-miR-1539	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28001
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47394
GSE199606_2_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26695
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW403	CCLE Cell Line Gene Expression Profiles	1.0	1.60507
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.65884
periventricular stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18397
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879216
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A464-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.071936
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14033
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11136
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3429
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7517_KD_SPF45_SRP216858	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Hypertension	CTD Gene-Disease Associations	1.0	1.31387
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.08663
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80483
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881325
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.01549
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.38171
Winged helix-turn-helix DNA-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14426
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923013
system process	GO Biological Process Annotations 2015	1.0	null
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08795
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
WM88	CCLE Cell Line Gene Expression Profiles	1.0	1.58785
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831795
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.07199
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13452
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1-26981420-C2C12-MOUSE-MUSCLE	ChEA Transcription Factor Targets 2022	1.0	null
hESC_Derived_CD56+_Ectoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.31081
hsa-miR-3545-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23244
Brain Lower Grade Glioma_LGG_TCGA-FG-8182-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3021
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43429
GSE116299_6_v_1_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.989727
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19743
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE111247_0_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
Endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47116
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851993
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11958
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978466
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98289
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05337
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27036
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909211
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19505
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.98611
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive congenital ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.361
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04442
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37496
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0726-SM-48FCN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12087
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924811
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14652
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17676
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.873329
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.61194
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07944
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6947
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.939579
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1462
Perturb_14772_KD_SP140_SRP076599	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.07852
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0741
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
hsa-miR-3974	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.5736
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76077
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958588
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20384
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.7129
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05586
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064443
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0628
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82773
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6965
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.74583
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59824
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13676
BT20	CCLE Cell Line Gene CNV Profiles	1.0	1.6708
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNTNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1521
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.983388
Perturb_12661_KD_RAB7_SRP017435	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.80718
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17767
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	1.0	null
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58008
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1259_KO_Bap1_SRP253039	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE122509,GSE122513_2_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.927051
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.870147
Prostate adenocarcinoma_PRAD_TCGA-HC-7075-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sp3_17923686_e12dot5_heart_lof_mouse_gpl1261_gds3058	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.543414
GABPA	ENCODE Transcription Factor Targets	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836889
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.631
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BC-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928406
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of TORC1 signaling	GO Biological Process Annotations 2025	1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Belinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136635
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.90594
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21882
hsa-miR-3938	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14227_KO_Lsd1_SRP064569	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.37757
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_4_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.08
CREB1	ChEA Transcription Factor Targets	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123943_4_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82218
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08409
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24624
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3324_KO_Tkt_SRP364774	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.53678
hsa-miR-4461	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929283
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09043
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	2.19001
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.21877
PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_CUTOFF_2_5_TOTAL-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83872
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00929
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00812
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Infantile neuronal ceroid lipofuscinosis_Brain_GSE6678	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.56661
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM370	DepMap CRISPR Gene Dependency	1.0	2.29962
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27866
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869494
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21211
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13841
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046935
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86698
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.63107
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02932
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.592506
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33437
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08442
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25194
ZFP57-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1682
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.86667
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905182
positive regulation of TOR signaling	GO Biological Process Annotations 2025	1.0	null
lytic vacuole membrane	GO Cellular Component Annotations 2025	1.0	null
TIMM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12612
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14335
HUTU80	CCLE Cell Line Gene Expression Profiles	1.0	1.67896
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-513b	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.092
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10398
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15794_KO_S1pr3/S1pr1/S1pr2_SRP234700	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.82867
GSE140322_3_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.855472
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9908
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05814
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.21877
Perturb_6562_KO_Zfp423_SRP105097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45259
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1703	DepMap CRISPR Gene Dependency	1.0	2.13403
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.84062
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041034
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.854352
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0938
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39858
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.876
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.919325
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333718
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14614
GSE124410_3_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33472
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_9_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59985
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37695
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-361-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00182
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15711
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70674
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48307
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27608
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH660	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50803
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-668	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67144
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2828
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.56733
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05173
hsa-miR-4696	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14835_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SUZ12	ENCODE Transcription Factor Targets	1.0	null
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85996
Isolated growth hormone deficiency type IB	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PLK1_druginhibition_181_GSE46856	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	3.52991
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5113-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885308
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936344
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A498-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vacuolar membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CBX3	ENCODE Transcription Factor Targets	1.0	null
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43264
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.01346
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34654
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4228
FOXO1_KO_GSE40655_481_mouse_T reg	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10794847-mmc6.xlsx-PIAS1_KD_down-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856262
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39216
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-IRF1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.15593
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925555
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20779
KDM5A	ENCODE Transcription Factor Targets	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2637
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.924947
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53808
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13372
abnormal kidney morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_20_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.48886
laterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68405
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970121
Perturb_11212_KO_Cd36_SRP351120	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.77819
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12708
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.14971
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.33089
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4653-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MYBL2	ENCODE Transcription Factor Targets	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7393
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44633
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548w	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.01179
Dot1l_DELETION_GDS4295_426_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 3 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64652
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Table_S5A_Upregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056121
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31598
hsa-miR-4756-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894538
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUES64_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.34267
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37738
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	2.85759
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3158-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
T98G	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05655
phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.49742
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPZ_02_176	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62149
KY821	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	1.08355
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87188
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26435
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17147
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23396
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27947
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379499
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6224
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042284
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-2.46092
Lung squamous cell carcinoma_LUSC_TCGA-77-8130-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.12703
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29849
PMC10350897-j_biol-2022-0528-S1.pdf-68-GPBP1L1_GPBP1L1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982322
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937761
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0587
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WM115	CCLE Cell Line Gene Expression Profiles	1.0	1.96832
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548y	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24114
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.54281
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESRRA	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4509	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE81193_3_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	2.18502
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895372
Perturb_6380_KO_Snf5_SRP271283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.74265
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.28996
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01196
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17297478-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83434
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.0894
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32469
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72112
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865305
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.14624
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.651375
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.903824
hsa-miR-548b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.1461
PPP1R1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1153
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910166
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.6069
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
OV7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29265
SW579	DepMap CRISPR Gene Dependency	1.0	2.02621
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36077
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08645
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12197_KD_ERCC6_SRP310546	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
RRP7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41356
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.50116
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42473
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149359_3_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-5654-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_10_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00511
GSE223008_5_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19087
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.1576
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleolus-like body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day2-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.34501
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1476
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10756
A-CA-04-2009(H1N1)MA_Day1_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73587
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.527
Perturb_4399_KO_STING1_SRP191307	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.8972
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10916
HT1197	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50865
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21578
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909649
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73803
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47128
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046631
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16843
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942373
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43087
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.236073
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069079
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.927203
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LOVO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09296
PRKAG3_KO_GSE4063_389_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58088
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.987555
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47481
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19738
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pontine central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66456
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A-CA-04-2009(H1N1)_Day1_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.38184
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02202
GSE147240_3_v_1_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
18234966-Table2	GeneSigDB Published Gene Signatures	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	137.373
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.83
CHD7	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4738-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Glutamate decarboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894504
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898351
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843901
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.977079
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42266
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73219
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07422
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Perturb_16376_Mut_Rps2_SRP277547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.97893
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34516
CBX2	ENCODE Transcription Factor Targets	1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.698475
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-935	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.604
KP2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.46107
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8877
sterol binding	GO Molecular Function Annotations 2025	1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79918
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4714
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.094779
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Malotilate_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.024117
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48923
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.850974
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5861
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914945
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31363
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99474
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01435
hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422292
Perturb_16919_KD_H19_SRP151268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.08777
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23833
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847169
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23698
TT	CCLE Cell Line Gene CNV Profiles	1.0	2.10328
GSE111138,GSE111149_1_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07819
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12005
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166317_3_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54871
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32896
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
v91	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
MCF7_Panobinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00972343
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10879
stomach	HPA Tissue Gene Expression Profiles	1.0	1.99095
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1466
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7407-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73E-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41886
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.6783
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34126
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891688
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10305_KO_Cxcl12_SRP114370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.23178
GSE142210_11_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-CA-04-2009(H1N1)MA_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.36733
MED31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38419
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832052
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0479
Medial preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0915
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.7626
Lytic vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116299_0_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEx Lung 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.95536
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25497
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JK-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64558
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74739
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYB_01_102	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61047
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
Vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62408
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10252
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.824083
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-1.09976
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07955
LN235	DepMap CRISPR Gene Dependency	1.0	2.18763
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hearing impairment	GWASdb SNP-Phenotype Associations	1.0	0.609951
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32833
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22547
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5413
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1681
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68746
Catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.906
cellular response to cholesterol	GO Biological Process Annotations 2025	1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18033
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873609
hsa-miR-645	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Lysosomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34224
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.33081
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909649
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.032
SKMEL5	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.73861
THP1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.44133
stomach	GTEx Tissue Gene Expression Profiles	1.0	2.04417
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12805
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01802
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	3.69098
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997098
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7999
hsa-miR-548ab	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE104508_0_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02064
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76255
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6306
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.0943
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.44776
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11233
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41128
Perturb_4491_KO_Tcf4_SRP072458	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3383
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.02336
Perturb_12648_KD_Igfbp5_SRP191022	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0876
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04635
Perturb_17816_KO_Nr1d1_ERP120331	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.6211
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25672
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86621
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03926
brain	HPA Tissue Gene Expression Profiles	1.0	1.02016
GSE149075_8_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217139
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25452
tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.255107
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845872
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_3_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21987
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_Dacinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100146
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01547
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23641
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T5JC-1826-SM-4DM6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841223
cognition	GO Biological Process Annotations 2025	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91921
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_8613_KO_Ctcf_SRP078142	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.73292
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78117
Perturb_13678_KD_DHX9_SRP018815	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.41203
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60531
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31953
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93312
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18622
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20715
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02384
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
Perturb_152_KD_Tmbim1/Pparg_SRP319128	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07732
Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884524
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cellular response to sterol	GO Biological Process Annotations 2025	1.0	null
E2F2_KD_GDS4094_447_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.99068
PMC6718408-41467_2019_11884_MOESM9_ESM.xlsx-YAP1_RELA_DEGs_mice_human-Human_Gene_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48153
sirolimus_mus musculus_gpl1261_gse21755	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62008
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13347
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35283
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.820734
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22641
PMC13127299-mmc2.xlsx-PBX1_kdRNAseq-hgnc_symbol_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
16728581-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21541
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54151
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7918-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891805
hsa-miR-656	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	177.397
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64136
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OH-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944283
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51471
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.05292
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42204
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3729
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35679
signal transduction	GO Biological Process Annotations 2015	1.0	null
K562_Dacinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146641
GSE113106_0_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14014
PMC10534007-Table_2.xlsx-S3_unique_up_MSC_V-817_elements_included_exclusively_in_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871586
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7138
Auxin efflux carrier	InterPro Predicted Protein Domain Annotations	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.951106
OSC20	DepMap CRISPR Gene Dependency	1.0	3.08228
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC202	DepMap CRISPR Gene Dependency	1.0	2.93479
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6411
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997916
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.937652
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00691
Type IC spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Perturb_6565_KO_Gja1_SRP377031	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.13843
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42272
Sarcoma_SARC_TCGA-QQ-A8VG-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942244
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30858
PKBalpha_KO_GDS1784_197_mouse_Embryonic fibroblasts (MEFs) - 48h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44473
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.716971
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18377
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0136
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.0414
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01368
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64527
E2F4	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1279	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
PMC9710014-12876_2022_2535_MOESM2_ESM.pdf-44-CSRNP3_CSRNP3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24631
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34654
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE189653,GSE203344_5_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39698
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29073
occluding junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.253653
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.462239
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.57733
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947421
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28848
GSE126463_4_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ	ChEA Transcription Factor Targets	1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63883
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLC-PRF-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01406
MAFK	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277197
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051332
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.15953
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PRRX1_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26777
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4127
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31151
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26213
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of BMP signaling pathway	GO Biological Process Annotations 2025	1.0	null
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07758
PRKAG3_KO_GDS1398_703_mouse_gastrocnemicus muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.28858
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17250_KO_Il17a_SRP069071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.21891
Perturb_10321_KO_Hnf4a_SRP282343	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03264
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC827GR5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52806
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of BMP signaling pathway	GO Biological Process Annotations 2025	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24258
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09445
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.56253
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.974852
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37858
negative regulation of cellular response to growth factor stimulus	GO Biological Process Annotations 2023	1.0	null
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29025
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28244
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37966
HS294T	CCLE Cell Line Gene Expression Profiles	1.0	1.47704
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.816
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18904
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855384
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86564
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23826
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9768
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28709
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.28149
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90421
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12783
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Follicular Variant Thyroid Gland Papillary Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893057
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54725
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16473
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33702
GTEX-S4P3-0526-SM-4AD58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922229
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13563
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14031
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2901
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31185
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.21043
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92134
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039931
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64067
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30038
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7852
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41817
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4475	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Perturb_15291_OE_Tp73_SRP134969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.0861
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	DepMap CRISPR Gene Dependency	1.0	3.26168
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426109
abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478145
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91893
hsa-miR-135b	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
GTEX-U8T8-1226-SM-4E3IH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853505
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02571
MCF7_AR-42_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142301
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	2.23921
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.39684
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Lung Injury_Lung Tissue_GSE1871	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.02174
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22232
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2955
SP2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05863
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990677
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61J-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17547
smoothmuscle_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.859684
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.273696
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11986
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50699
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.2987
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31728
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47963
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40586
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25679
u266	HPA Cell Line Gene Expression Profiles	1.0	1.71464
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73355
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5164-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fenofibrate_SW480	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0102668
GATA2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARalpha_OE_GDS2289_244_mouse_Skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.582019
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.907811
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08841
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.46015
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.068
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03975
GTEX-RTLS-2626-SM-46MUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27144
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28182
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20249
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68666
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79508
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18345
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10013
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
hsa-miR-4697-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
DEP domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11464
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96596
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.2713
Perturb_124_KD_Tcf7l2_SRP100171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.60956
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269521
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03186
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.19412
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23454
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular response to amino acid starvation	GO Biological Process Annotations 2025	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972835
hsa-miR-509-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_25_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13944
hsa-miR-769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06035
GTEX-R53T-1226-SM-48FCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31611
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.20703
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13157
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.234
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
GSE142210_4_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836306
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84156
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.217
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887587
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48692
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15491
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895369
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16841
PCIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21507
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
PMC9882185-media-2.xlsx-Rbm12-specific_B2-AR_targets-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.36897
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBK1_druginhibition_188_GSE53658	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.44676
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	1.0	3.57196
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24295
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38086
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71433
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82189
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08624
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74148
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38691
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77886
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58752
hsa-miR-3200-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30728
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19743
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29139
POU2F2	ENCODE Transcription Factor Targets	1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Seh1-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
Locus ceruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27366
USF2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1179	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75403
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38747
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20136
SW156	DepMap CRISPR Gene Dependency	1.0	3.70706
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1946
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.9168
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04936
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15292
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0177
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039204
Auxin efflux carrier complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.079
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8781_KO_DNMT3A/DNMT3B_SRP186642	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.96479
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01115
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.531862
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.974151
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.762988
hsa-miR-664	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.15089
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2473
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.9831
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
Perturb_14675_KO_RpL13a_SRP090469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.70943
Anterior group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12845
dexamethasone_rattus norvegicus_gpl1355_gds3746	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3PL-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02666
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044577
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0812
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944857
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44949
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32293
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26282
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69399
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900932
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17199
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77413
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARS-Cov_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.26921
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08301
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-548j	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46416
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GM2 gangliosidosis, AB variant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00408
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06597
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2984
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1621
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124704
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59818
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26269
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070734
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05479
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.88708
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52279
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_3_AP1_Up_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842416
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21817
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12914
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03994
Striatum ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22164
hsa-miR-4477b	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.185
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46683
Perturb_15364_KO_Mef2c/Mef2d_SRP064307	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31232
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.265
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4288	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11697_OE_SASP_SRP278399	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887791
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1488
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3613
Perturb_1004_OE_Bach2_SRP158472	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43788
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2625
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06522
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44128
r4 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01452
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39494
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548h	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2846
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35297
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1703
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23171
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28106
RAD21	ENCODE Transcription Factor Targets	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4392212-gutjnl-2013-306620-s9.pdf-4-SMAD4_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124410_6_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.36494
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J4-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916833
CPC-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
GSE86813,GSE86814_0_v_1_atf7ip_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.14296
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23931
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35496
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72383
UPCISCC152	DepMap CRISPR Gene Dependency	1.0	2.23207
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03991
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00333
Retina	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97567
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03972
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.976523
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91371
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
bed nucleus of the external capsule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97905
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NFIC	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73498
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49118
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1947
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0193
PRPF38B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62085
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLR26	CCLE Cell Line Gene CNV Profiles	1.0	1.47466
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85982
Perturb_5903_KD_DDX5_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.57259
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1387
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965427
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05173
SNU478	DepMap CRISPR Gene Dependency	1.0	2.51803
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04092
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.598
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
Eye-melanocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.17703
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.90041
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70643
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38317
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.098593
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39552
Perturb_13017_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.40769
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16754
Perturb_1709_KO_Tox_SRP054249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.08963
EW8	DepMap CRISPR Gene Dependency	1.0	4.28542
Perturb_1564_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.3178
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19895
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.2203
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09683
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.878845
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27366
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.832352
K562_Dacinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128406
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.9305
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37858
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.60681
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08853
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sensorimotor area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69831
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE198165,GSE198166_0_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89955
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.788252
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GN-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14302
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42413
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TET2_KO_GDS4287_430_mouse_CMP - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96289
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00481
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7585-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4704-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83894
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06767
MCF7_Panobinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01027
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875248
DAOY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62621
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valproic acid_homo sapiens_gpl6244_gse23909	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	4.95132
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_3296_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3507
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880157
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907146
GATA1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.251718
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
NCIH196	Achilles Cell Line Gene Essentiality Profiles	1.0	1.18254
GSE174383_4_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39247
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16718
CEBPD	ENCODE Transcription Factor Targets	1.0	null
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0702
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.34083
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38024
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27898
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8708
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59879
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964477
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_11_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13951_KD_ASCL1_SRP201348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4781-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01406
GSE103297_1_v_0_glis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73627
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16626
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836711
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.93567
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957189
P32-ISH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.525095
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987416
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3669
MCF7_Quisinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00807486
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99114
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5958
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Endopeduncular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3197
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41289
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863289
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.688
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858232
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95217
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00841
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.47005
hsa-miR-888	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36231
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830191
Lonafarnib_SW480	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00894657
chr2_174434588_G_T_b38	GTEx eQTL 2025	1.0	1.86083
MCF7_Pracinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122362
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.74979
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.951649
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90024
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04125
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1975	DepMap CRISPR Gene Dependency	1.0	2.10223
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4685
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LHX2_LHX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38576
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997091
SUZ12	ChEA Transcription Factor Targets	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.75977
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.949414
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863926
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.70474
MCIXC	DepMap CRISPR Gene Dependency	1.0	6.74436
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_35_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
lysosome	GO Cellular Component Annotations 2025	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89318
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12514
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953225
hsa-miR-548ak	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84267
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
CMPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69175
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952446
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62822
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936241
19286929-SuppTable2n	GeneSigDB Published Gene Signatures	1.0	null
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	1.88755
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28926
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80201
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SARS-CoV MA15_Day7-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63627
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905383
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.900135
PHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99711
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4802-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.3026
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352227
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
Fibrosis	CTD Gene-Disease Associations	1.0	1.31897
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.48045
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.826147
GSE145476_2_v_3_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38781
GSE159206_1_v_3_drd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4775-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5519_OE_LRG1_SRP386433	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.57223
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46712
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.741538
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87018
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25165
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36203
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50554
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12571657-DataSheet3.pdf-12-ENSG00000188313_PLSCR1	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21169
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cholecalciferol_mus musculus_gpl339_gse18993	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32677
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35215
hsa-miR-4435	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3415
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8775
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05753
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40129
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62537
PMC11588066-pnas.2410331121.sapp.pdf-84-ESR2_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE212488,GSE218420_1_v_2_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12312
RFX5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5333
hsa-miR-24	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.34054
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240996
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989786
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	3.47528
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2649
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.5812
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15579
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09942
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02202
bewo	HPA Cell Line Gene Expression Profiles	-1.0	-1.03901
TRIM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17033
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21069
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059798
Perturb_12143_KO_Lgals9_ERP122370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.46483
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13674
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67759
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.64563
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
auditory system disease	GWASdb SNP-Disease Associations	1.0	0.709078
Perturb_3293_KD_RORA_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lysosomal lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
NCIH520	CCLE Cell Line Gene Expression Profiles	1.0	1.63982
hsa-miR-1257	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29232
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982717
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RERFLCAD1	DepMap CRISPR Gene Dependency	1.0	2.79502
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4893-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PU.1_KD_GDS2411_175_mouse_Preleukemic hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A-VN-1203-2004(H5N1)_Day4-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.3089
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927607
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.40774
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CFPAC1	Achilles Cell Line Gene Essentiality Profiles	1.0	2.43489
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	190.286
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50663
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3336
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28531
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41741
Prostate adenocarcinoma_PRAD_TCGA-FC-7961-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cognition	GO Biological Process Annotations 2023	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32357
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01613
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48847
NELFE	ENCODE Transcription Factor Targets	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_0_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80429
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03868
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1875
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A388	DepMap CRISPR Gene Dependency	1.0	3.31633
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9265
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60523
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41178
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63781
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.965527
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40763
GSE223008_6_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SW1783	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61418
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08669
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00482
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12571657-DataSheet3.pdf-12-PLSCR1_PLSCR1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.42342
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fallopian tube	HPA Tissue Gene Expression Profiles	-1.0	-1.30947
MCF7_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120249
GSE116299_4_v_5_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.86538
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
MCC13	DepMap CRISPR Gene Dependency	1.0	2.64614
KCIMOH1	DepMap CRISPR Gene Dependency	1.0	2.37645
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4032
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866857
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159049_3_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.11116
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_150_KD_Fto_SRP144034	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10919
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.915
Perturb_11133_KO_Hdac3_SRP082562	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.50168
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07755
hsa-miR-4276	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26556
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00316
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46242
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7549
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06146
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41036
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.6858
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58073
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055927
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.854864
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PL4	DepMap CRISPR Gene Dependency	1.0	2.88093
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10487
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33138
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877669
hsa-miR-548i	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22029
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.39154
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3061
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21875
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918014
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34952
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.06841
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03119
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.41485
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74805
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	141.227
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
LAMA84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5069
single-organism localization	GO Biological Process Annotations 2015	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2951
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12650_KD_IGFBP5_SRP191422	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0804
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6293073-LSA-2018-00153_TableS3.xlsx-C_KD_Tr_4_genes-66_genes_upregulated_upon_knockdown_of_Tr_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of BMP signaling pathway	GO Biological Process Annotations 2023	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126402_4_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06045
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37104
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17111
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.4732
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	2.29991
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.974496
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOCS3_KO_GDS3149_8_mouse_multiple cell types	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70345
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56536
GSE146687_2_v_3_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985126
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940404
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60863
CHD1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5606034__F4	PFOCR Pathway Figure Associations 2023	1.0	null
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.27181
ALG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52788
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925282
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22942
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058379
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110580_1_v_0_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952532
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47408
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
peritoneal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388912
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.817
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Perturb_15612_KO_Net39_SRP273304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.80095
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20211691-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Perturb_5920_KD_KAP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.49089
A-VN-1203-2004(H5N1)_Day2-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58266
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88231
Perturb_17520_KO_Cns2_SRP041655	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.31546
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24871
hsa-miR-4799-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24352
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22474
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70643
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7357
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7312
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72962
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80508
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209582_1_v_0_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16068
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36845
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09543
KDM4A	ENCODE Transcription Factor Targets	1.0	null
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.34465
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02962
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
KICSTOR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.10739
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14784_KO_Cdk7a_SRP257907	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.11214
GSE148692,GSE148695_7_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-BRCA_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839106
VAMP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06915
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49029
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21748
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.93992
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045635
icSARA deltaORF6_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.18275
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of VPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24227
SKMG1	DepMap CRISPR Gene Dependency	1.0	2.03838
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_10707_KO_RbpJ_SRP354352	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.1867
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961937
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070734
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964477
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC5303304-13073_2017_407_MOESM4_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S3_Genes_differentially_expressed_by_24h_RA_and_48h_Dox_co-treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887587
ESRRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal lymph node morphology	MGI Mouse Phenotype Associations 2023	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12033
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50374
Hypertrophy	CTD Gene-Disease Associations	1.0	1.47115
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_944_KO_Bhlhe40|Bhlhe41_SRP216680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.626
GSE108675_2_v_1_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38541
IM9	DepMap CRISPR Gene Dependency	1.0	2.60795
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27655
GSE199606_5_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42542
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24085
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.59479
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3295_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.5609
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2491
r3 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52866
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67199
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4342_OE_MIR9/MIR124_SRP271664	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997037
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7390-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-382	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216613
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02384
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.0412
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.3512
Perturb_8394_KO_Fak_SRP279401	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58575
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19006
hsa-miR-4678	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE211286_7_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08982
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70616
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149075_8_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14785_KO_Cdk7a_SRP257907	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.1262
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pentamidine (isethionate)_SW480	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0114234
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.17893
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_8_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17379
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051575
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90005
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22649
endometrium	HPA Tissue Gene Expression Profiles	-1.0	-1.03724
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63347
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28584
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28103
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07175
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16607
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10038
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051746
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infertility, Female	CTD Gene-Disease Associations	1.0	1.12151
GSE147240_3_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.20031
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49035
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943535
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884693
Perturb_17820_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.18228
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.989378
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51455
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837614
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15632
NCI-H2081	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.33063
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02409
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050678
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82066
all	GWASdb SNP-Phenotype Associations	1.0	0.028555
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59408
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73029
BC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14263
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39349
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00677
Learning Disorders	CTD Gene-Disease Associations	1.0	1.53308
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_8633_KO_Sh3gl1/Sh3gl2_SRP082219	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.46316
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90647
GSE216538_5_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_14946_KD_Nmnat1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.79593
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.59585
AA-58-FJ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416946
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06158
TET2_KO_GDS4287_431_mouse_GMP - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84714
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214514_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE90019,GSE90020_1_v_3_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0164
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE85302_0_v_1_kat6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CPSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39563
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.82568
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39662
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52916
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14743
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HG3	DepMap CRISPR Gene Dependency	1.0	4.71819
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25963
enlarged kidney	MGI Mouse Phenotype Associations 2023	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57206
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827693
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV MA15_Day1_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.31088
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22164
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COPI-coated Golgi to ER transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
biological regulation	GO Biological Process Annotations 2015	1.0	null
PMC4383005-ncomms7500-s3.xlsx-Supplementary_Table3-Supplementary_Data_2_HES5_vs_HES5-_expression_intensity_ratios_during_NSC_progression_HES5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5482637-oncotarget-08-36040-s002.xlsx-Table_S5-Table_S5_candidates_of_GATA3_related_genes_in_breast_cancer_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCTN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04243
Endopiriform nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59285
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Quisinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00956114
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36832
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11591
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03217
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Prostate-t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.437212
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53069
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48243
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.093
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868057
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22666
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4114
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54075
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975479
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43194
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-TPRX1_UP-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_up_to_an_FPKM_of_at_least_2_TPRX1	Rummagene Transcription Factor Associations 2026	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.852109
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846733
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9399
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24213
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU61	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53692
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35846
ML-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40983
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.920531
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998095
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11864
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26704
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OV90	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.74394
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884853
Choline	CTD Gene-Chemical Interactions	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01287
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09855
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10362
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94847
ficolin-1-rich granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.573
PPARG	ChEA Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5606034__F5	PFOCR Pathway Figure Associations 2024	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.149
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23877
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38064
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01578
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828359
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.999203
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_2_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18663
IM95	DepMap CRISPR Gene Dependency	1.0	4.37962
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04481
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.71547
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2751
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_29_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927641
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SW1417	CCLE Cell Line Gene Expression Profiles	1.0	1.78399
A1207	Achilles Cell Line Gene Essentiality Profiles	1.0	1.87235
Urate levels (BMI interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64842
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03791
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33518
response to amino acid starvation	GO Biological Process Annotations 2025	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.459
Perturb_4308_KO_FOXM1_SRP328179	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SW1783	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00351
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
hearing abnormality	GWASdb SNP-Phenotype Associations	1.0	0.380587
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.33029
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-135a	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
Perturb_12683_KD_circEZH2_SRP388087	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.8972
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972645
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12471
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879308
abnormal seminal vesicle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.829971
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16048
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299242
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.15661
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72616
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of TORC1 signaling	GO Biological Process Annotations 2025	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8358
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45229
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040338
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5520_OE_LRG1_SRP386433	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.17549
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56489
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3370-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65534
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.49434
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.3456
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5253
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05579
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22149
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199606_1_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928033
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KAT2B	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4495
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
GSE216538_0_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23952
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9207509-DataSheet_1.docx-3-FOXK1_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
ADNP_Deficiency - NULL MUTATION_GDS2540_692_mouse_E9 embryos - Homozygous mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Salivary_Gland-cd8-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.687513
hsa-miR-4728-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null