association	dataset	threshold value	standardized value
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6391
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05518
GNPDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47534
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844823
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pathologic nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0411
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16066
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835691
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.8949
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044082
night blindness	HPO Gene-Disease Associations	1.0	null
GSE255680_1_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05018
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.15885
hsa-miR-3690	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52678
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Fhm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
GTEX-OIZH-0226-SM-2YUMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
Pallidum, ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23307
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.4633
SMARCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07451
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
CAKI2	DepMap CRISPR Gene Dependency	1.0	2.82423
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2075
three	GeneRIF Biological Term Annotations	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18237
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.924
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42251
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05964
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19954
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.197125
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24569
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841052
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.994251
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neurological system process	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.904706
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60679
Hereditary choroidal atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40595
ZNF268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.05046
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00048
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866972
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.514
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45097
MAPKAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61766
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96702
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02051
VSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16148
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871653
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32548
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05917
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.926241
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992759
MDA-MB-361	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
ahl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.642
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65701
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.47074
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95901
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827714
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985736
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08164
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998267
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31734
BRPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25125
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01364
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955799
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58887
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33895
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879655
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.841043
ZNF717	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52355
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72652
Birdshot chorioretinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80874
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0851
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE182835,GSE182836_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72809
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937445
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.2319
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881289
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2507
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF791	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77529
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44758
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945726
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47611
hsa-miR-4736	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68224
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.164315
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77231
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10087
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Congenital stationary night blindness 1B	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
FAM131A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47949
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47001
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4507	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Exudative vitreoretinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52911
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-KLF4_correlates_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89705
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.984339
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Ovarian cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.909691
RASSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03654
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17767
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.30496
Choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.49423
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79108
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.10364
OCUBM	DepMap CRISPR Gene Dependency	1.0	5.3681
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34687
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87299
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058194
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.989
other	GeneRIF Biological Term Annotations	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61875
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
VCAP	DepMap CRISPR Gene Dependency	1.0	4.62879
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06453
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992886
CFPAC1	CCLE Cell Line Gene CNV Profiles	1.0	2.09556
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47579
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34863
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26748
SIRT3_KO_GDS4817_417_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OSC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPATA5L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.569
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890308
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24232
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.837364
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14983
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24805
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0113
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92807
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1606
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02954
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05664
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HT29	CCLE Cell Line Gene CNV Profiles	1.0	1.75374
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32434
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8394
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79487
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07571
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06931
SNU119	CCLE Cell Line Gene CNV Profiles	-1.0	-3.15359
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864846
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3663-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05815
HCC366	DepMap CRISPR Gene Dependency	1.0	5.60327
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blindness	GeneRIF Biological Term Annotations	1.0	null
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49863
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23009
Malignant hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918629
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23395
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.960729
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081812
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42501
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.33306
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34234
H2810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypophysis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NB5	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.86102
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11028
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BC-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
visual perception	GO Biological Process Annotations 2023	1.0	null
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.296
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	0.969295
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.488
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26904
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GATA5_KO_GSE47425_386_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92546
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870863
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1685
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02344
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941729
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05515
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06632
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78014
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60564
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.29118
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0686
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.91102
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09307
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.253
RMG-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3149
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.56218
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2811
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.939826
Congenital disorder of glycosylation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30557
Lung adenocarcinoma_LUAD_TCGA-44-6775-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39178
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.974626
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961707
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54712
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20413
cortical cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.301425
DP-agonist13	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63234
HDAC1	ENCODE Transcription Factor Targets	1.0	null
TNS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74201
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.24138
congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.30863
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46535
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51589
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81242
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
embryoday9.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.954982
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35035
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07002
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
496100585_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4734
Pseudoxanthoma elasticum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995794
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.974221
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.663
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85124
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.19679
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135514_2_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44536
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17q12 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
GTEX-OHPK-0426-SM-3MJH3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915718
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05797
Perturb_14680_KO_P2Y14_SRP044222	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.08941
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39934
Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.915207
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38578
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99371
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81369
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brown-Vialetto-Van Laere syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43932
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02813
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8015
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893487
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye-muller cell	Tabula Sapiens Gene-Cell Associations	1.0	2.39718
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12307
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72377
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4445	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Ocular albinism 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68582
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.57066
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
FOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13935
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07299
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02128
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51849
BTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94214
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01609
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19517
496100588_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19011
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4896
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74196
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.844494
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39319
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75877
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.069
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33849
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88425
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874803
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41072
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.51013
SYPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88749
NCIH810	CCLE Cell Line Gene CNV Profiles	1.0	1.33321
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26598
HEPG2	DepMap CRISPR Gene Dependency	1.0	2.17535
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27375
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56923
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06453
Neuronal ceroid lipofuscinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10039511-12864_2023_9238_MOESM1_ESM.xlsx-FOXO1_group-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
harboring	GeneRIF Biological Term Annotations	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12127
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15069
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49345
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37193
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82896
Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4215
IZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843525
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925531
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	2.20984
hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51082
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42308
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SISO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	2.09814
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65445
MCC26	DepMap CRISPR Gene Dependency	1.0	2.27535
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859192
A388	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2312
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046446
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9557
Lasmiditan	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.21
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15554
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9079
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980311
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.73803
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.216
MKN74	DepMap CRISPR Gene Dependency	1.0	3.31747
POTEI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14546
Retinal dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
T3M4	DepMap CRISPR Gene Dependency	1.0	2.29752
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96137
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25101
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13487
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967304
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09696
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49974
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15039
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43213
Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUP-T3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93785
GSE178267_2_v_4_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50203
NKX6-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40112
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73584
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23368
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0693
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Geleophysic dysplasia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885901
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53899
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51371
CFPAC1	DepMap CRISPR Gene Dependency	1.0	2.05942
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.852807
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00755
Metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.692623
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.687
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91832
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12566
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1707
abnormal eye electrophysiology	MPO Gene-Phenotype Associations	1.0	null
Retinal vein occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13102
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90527
horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.847904
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61591
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18164
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63673
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38331
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08495
hsa-miR-4436b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866938
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66809
KYSE-410	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
HCC515	DepMap CRISPR Gene Dependency	1.0	4.65278
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4858
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18108
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23395
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	2.12743
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38644
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09227
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65653
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87654
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65168
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5331
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30408
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38719
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00387
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00899
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7732
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54187
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45164
Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03416
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885193
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23949
PLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1005
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.12894
Cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
FOXC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9445
PPARGC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37697
RASSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48746
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.16894
M040416	DepMap CRISPR Gene Dependency	1.0	2.72907
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.64093
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03832
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55914
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975671
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MORCPR	DepMap CRISPR Gene Dependency	1.0	3.3638
PRDM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83284
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03867
CNKSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13456
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38856
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4555
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52221
CENPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82464
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2435
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pallidum (globus pallidus complex)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10632
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22889
GSE112860_9_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76932
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063163
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29294
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68864
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.12
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0285
nystagmus	HPO Gene-Disease Associations	1.0	null
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83386
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC14	DepMap CRISPR Gene Dependency	1.0	5.50256
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19601
POGZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32075
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33347
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40092
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8664
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.66388
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9055
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04777
LN319	DepMap CRISPR Gene Dependency	1.0	3.08298
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863141
Retinitis pigmentosa 86	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4148
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850046
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0822
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77537
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08388
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43256
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24467
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Perturb_14796_OE_Mycn_SRP094656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.60417
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54732
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0318
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71433
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06442
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73284
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9539_KD_Utx_SRP066186	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4546
Dendrite	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE157594_5_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962446
ECGI10	DepMap CRISPR Gene Dependency	1.0	3.23911
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24227
GYPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32851
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08595
icSARS-Cov_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.18064
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82539
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88926
KDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19603
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18088
PMC3738137-bjc2013359x6.pdf-3-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
visual impairment	HPO Gene-Disease Associations	1.0	null
Reelin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.33
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.096
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16033
JOPACA1	DepMap CRISPR Gene Dependency	1.0	2.3947
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
SW13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850428
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04103
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16625
Color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33997
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22423
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920898
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19268
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42344
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0316
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95577
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.917231
Superior colliculus, optic layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28376
Perturb_11763_KO_Irgm1_ERP020504	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.22245
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08787
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03812
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1359
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.207
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51812
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14161
AGK2	DeepCoverMOA Drug Mechanisms of Action	1.0	1.23
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19309
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81846
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901311
dendrite	GO Cellular Component Annotations 2025	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0354
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7927818-AAC.01755-20-s0002.xlsx-Supplemental_Table_1-Supplemental_Table_1_List_of_significantly_altered_genes_in_MDMs_differentiated_in_the_presence_of_PrEP_FTC_v_No_Drug_TDF_v_No_Drug_FTC_v_TDF_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4512	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Lung adenocarcinoma_LUAD_TCGA-97-8179-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16412
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39749
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
KDM1A_KD_GDS5055_457_mouse_adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10711
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.876129
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6302
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
CLIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31208
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41254
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844358
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Perturb_14446_KO_Kdm4a_SRP101992	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.75925
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15558
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.087
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72352
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13995
Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC-3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.1519
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2653
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53625
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6789
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992531
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64484
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25111
Retinal vascular occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58614
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.77025
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
strabismus	HPO Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33372
Lung squamous cell carcinoma_LUSC_TCGA-56-8629-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55992
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.979398
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885901
HNRNPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32846
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87102
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50656
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
hsa-miR-4457	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
an3ca	HPA Cell Line Gene Expression Profiles	1.0	0.882423
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32178
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01364
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56136
congenital stationary night blindness	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dendritic tree	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01034
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	1.20754
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.961628
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89419
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
FIBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27252
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00756
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7222
ENSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95037
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31109
TBK1_druginhibition_188_GSE53658	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.48681
Retinitis pigmentosa 87	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31888
SLC39A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85975
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02721
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.940772
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38638
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59505
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19309
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76569
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06262
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70758
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31955
Substantia innominata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1626
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40333
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NOTCH1_Deficiency_GDS2848_635_mouse_Hair follicles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865507
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35511
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83344
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67609
screening	GeneRIF Biological Term Annotations	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840435
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30314
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36279
GPCR, family 3, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6493
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SETSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0208
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
HSD3B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27286
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6231
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.14539
PLD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04502
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42539
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.1965
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.67549
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5257
ADRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08746
NGP	DepMap CRISPR Gene Dependency	1.0	2.62205
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919093
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2086
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4271
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44649
MDA-MB-330	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964085
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00756
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01378
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46663
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29997
hsa-miR-4533	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NR1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08645
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96266
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38394
Abnormality Of Macular Pigmentation	DisGeNET Gene-Disease Associations	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9569
Brown-Vialetto-Van Laere syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1541
cell cortex part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.244962
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079086
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.987023
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22254
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01635
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39053
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05337
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87866
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995765
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.059597
JJN3	CCLE Cell Line Gene CNV Profiles	1.0	1.44961
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87357
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30448
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48579
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90772
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01286
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
CORO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32936
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89867
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06335
STF-31	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.58
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98126
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827231
skbr3	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8406
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12754469-ab-25-0159-Supplementary-1.pdf-11-TEAD3_TEAD3	Rummagene Transcription Factor Associations 2026	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15964
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866972
GI-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.71552
KCNK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54746
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04892
GSE173873_2_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCLRE1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81953
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843302
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
Congenital muscular dystrophy-dystroglycanopathy type A1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50634
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47523
UMC-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23125
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60816
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885193
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857792
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
HSC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05244
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34437
Choroidal sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34887
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18002
C1QL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.2152
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53604
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03548
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11127
SMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67711
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
C2CD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54406
Achromatopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253908
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.212
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248361
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89422
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02863
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16510_OE_Tafazzin_SRP284254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36811
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8094
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
sensory perception of light stimulus	GO Biological Process Annotations 2025	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39674
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50112
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15266
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0069
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.899
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2972
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNB1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32531
Perturb_10358_KD_Ascl1_SRP340223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.7986
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25177
GTEX-WH7G-2226-SM-3NMBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842786
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19208
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13551
hsa-miR-3940-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-563	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TEN	CCLE Cell Line Gene CNV Profiles	1.0	1.93874
GSE173873_5_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1231	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.194
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28705
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37579
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96323
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESS1	DepMap CRISPR Gene Dependency	1.0	2.00114
GSE250089_0_v_3_epcam_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01641
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85663
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828083
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.982
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33664
GSE135334,GSE136010_2_v_3_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.719
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39383
SLC43A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77258
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89838
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69253
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00737
Exotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
HOP62	DepMap CRISPR Gene Dependency	1.0	2.36334
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52813
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13678
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62348
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	3.02122
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17353
ZBTB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59567
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.973801
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15328
OPM2	DepMap CRISPR Gene Dependency	1.0	2.63686
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17093
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91821
F5	DepMap CRISPR Gene Dependency	1.0	4.10922
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2777
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87844
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.942
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
Leber congenital amaurosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.949963
lateral orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957094
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857053
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50755
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81988
Coloboma of optic nerve	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828015
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1472
JOSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17368
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93921
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35829
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.055
STC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52319
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871705
Retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PCI-30	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.1233
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	3.6329
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4101-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00554
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11686
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81166
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87763
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940439
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
Veliparib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.612
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9569
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50755
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919324
GTEX-VJWN-0626-SM-3NMAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.87074
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5208
mantle zone of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10554
SNX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72738
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21496
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18517
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08388
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4549
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03284
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.146094
FBXO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30108
LIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8098
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0465
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HBEGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31434
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07858
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
Myopia	DisGeNET Gene-Disease Associations	1.0	null
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Strabismus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57896
NCI-H250	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078516
RT11284	DepMap CRISPR Gene Dependency	1.0	4.08141
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.886479
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55229
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27717
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79801
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56137
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98189
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72709
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Night Blindness	DisGeNET Gene-Disease Associations	1.0	null
GDF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32282
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53387
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43944
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903956
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.922055
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905501
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36976
NCIH647	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52576
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51978
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17179
OFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30376
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC5094751__F12	PFOCR Pathway Figure Associations 2024	1.0	null
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27553
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842787
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-01A-21R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886822
THAP1_02_46	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.41504
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05259
ZNF331	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86301
Diamond-Blackfan anemia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.592
GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.365
PMC11952327-media-1.pdf-1-ENSG00000184492_FOXD4L1	Rummagene Transcription Factor Associations 2026	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51579
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12055
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30443
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17276
IGHMBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92427
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74642
Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00556
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60884
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30173
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2814-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919911
inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.91908
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
GLUL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22583
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30704
ZNF92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75813
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04285
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO678	DepMap CRISPR Gene Dependency	1.0	2.25929
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62256
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918276
DDX19A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81524
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.09296
SLC30A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85873
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.892136
CTDSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39836
Central retinal vein occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13196
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63858
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69669
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14187
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912432
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5332
PNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11234
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7935
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC44	DepMap CRISPR Gene Dependency	1.0	5.3052
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.31184
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46128
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876046
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895036
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11887
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3371
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860307
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80383
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41307
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JO-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	HPO Gene-Disease Associations	1.0	null
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
night blindness, congenital stationary (complete), 1e, autosomal recessive	OMIM Gene-Disease Associations	1.0	null
Retinal detachment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-451b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03995
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
NSMCE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33054
Ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.552
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06893
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4227
Peripheral retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43893
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15906
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29496
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899672
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19095
Congenital stationary night blindness 1E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.085
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07081
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MYB	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60086
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72195
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96271
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.56808
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30087
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03832
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96754
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1534
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	0.857034
hsa-miR-3182	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94546
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4098
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49235
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.852807
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8CQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28399
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836804
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18916
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961707
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842077
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975876
GSE152637_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11937
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61627
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RHOQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70372
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.933142
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.1184
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.069
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ALOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85915
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.377
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85386
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.96594
ATP5F1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46715
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.19426
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02242
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84828
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10693
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.268
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.72
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79479
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
mantle zone of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08185
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.07
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15944
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
night	GeneRIF Biological Term Annotations	1.0	null
GSE173873_4_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838548
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11126
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857339
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6875
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50378
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.768
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96371
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902698
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.650768
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1563	CCLE Cell Line Gene CNV Profiles	1.0	1.84255
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974873
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61545
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
X-linked juvenile retinoschisis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37729
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58748
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.187
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30627
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88773
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01746
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05319
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63585
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13259
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052011
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63005
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27069
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28186
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
HNRNPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44431
GSE173873_2_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.86973
SLC25A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58921
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72265
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.18131
GSE65617_2_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08817
cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ESRRA	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
NB(TU)1-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1818_KO_Adam17_SRP394864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.24171
GSE197562_1_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31301
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
hsa-miR-4291	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90529
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84276
INPP5J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56157
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48078
Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56684
PEHO syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43495
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21053
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92195
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Striatum-like amygdalar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47143
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28346
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15774_KO_Uxt_SRP240277	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.5047
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hypophysis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41445
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
THP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22156
Aniridia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
SKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Congenital stationary night blindness 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
Congenital stationary night blindness	ClinVar Gene-Phenotype Associations 2025	1.0	null
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0456
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81099
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6878
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital muscular dystrophy-dystroglycanopathy type A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.48763
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55647
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6275
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74021
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56295
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17883
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884872
Syndactyly type 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Optic atrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
ZFC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77217
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8547-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
FAM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85166
IHH-4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.02925
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34408
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stargardt disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.088
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24841
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917187
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0579
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997015
JAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61152
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35108
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
DHX57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67382
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08907
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70584
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55711
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.983018
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01953
U-CH2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2K	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
pc3	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
Brain Lower Grade Glioma_LGG_TCGA-IK-7675-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89137
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41416
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.890905
TT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
visual perception	GO Biological Process Annotations 2025	1.0	null
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96038
HEC6	DepMap CRISPR Gene Dependency	1.0	2.49877
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92446
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21318
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.38086
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53423
congenital	GeneRIF Biological Term Annotations	1.0	null
Renpenning syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.694
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.34723
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Acrodermatitis enteropathica	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
ESRRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13995
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03102
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5
abnormal rod electrophysiology	MPO Gene-Phenotype Associations	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MCF7	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.76895
X-Linked Csnb	DisGeNET Gene-Disease Associations	1.0	null
UMUC7	DepMap CRISPR Gene Dependency	1.0	2.72678
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947029
4EGI-1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16278
hsa-miR-3679-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08348
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02606
127399	DepMap CRISPR Gene Dependency	1.0	3.94071
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33772
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892211
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174735_4_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYAE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19066
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862035
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7893
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75351
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27408
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08366
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00594
NCIH2030	DepMap CRISPR Gene Dependency	1.0	2.30296
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.41444
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55773
superior parietal lobule, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.969958
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PF-514273	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
sensory perception of light stimulus	GO Biological Process Annotations 2023	1.0	null
FUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83719
RLIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98686
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898846
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05134
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01223
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.85776
PALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15885
PAX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00512
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44493
GSE156033_1_v_2_sparc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41935
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
receptor activity	GO Molecular Function Annotations 2015	1.0	null
KYSE410	DepMap CRISPR Gene Dependency	1.0	4.74724
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3455
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052153
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08388
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SLC2A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95496
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19081
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.1702
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851253
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71444
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49197
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32006
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62038
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.953495
KDM1A_KD_GDS5055_367_mouse_adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	89.8169
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Waisman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042276
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19578
GATA3-21867929-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02475
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09628
SW982	DepMap CRISPR Gene Dependency	1.0	2.73072
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49912
ASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38046
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.911
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24975
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826355
TOV-112D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE9	DepMap CRISPR Gene Dependency	1.0	2.36476
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49091
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055159
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.95233
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83371
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04608
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60472
sanger	GeneRIF Biological Term Annotations	1.0	null
bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.01825
OCT4_KD_GDS1824_135_mouse_embryonic stem (ES)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65968
H3-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73527
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.635
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
GCIY	DepMap CRISPR Gene Dependency	1.0	2.69421
Lung squamous cell carcinoma_LUSC_TCGA-43-8116-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39867
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00474
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046204
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11626
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_13811_KD_Zfp609_ERP013418	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.6146
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883782
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuron projection	GO Cellular Component Annotations 2025	1.0	null
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23019
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18232
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0961
eye and adnexa disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
SELENOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8321
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
orbital frontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04938
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870137
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1681
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39323
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
TUR	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.95722
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9488
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.47069
Synaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35494
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31068
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0251
x-linked recessive inheritance	HPO Gene-Disease Associations	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09906
brain	GTEx Tissue Gene Expression Profiles	1.0	2.18679
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02957
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43049
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78544
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.00993
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18237
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.72206
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19126
SNU1079	DepMap CRISPR Gene Dependency	1.0	3.25939
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199681
KLF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58137
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62852
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
USP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51316
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64955
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40874
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89123
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58871
GSE151494_1_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23516
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986967
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32548
Syndromic X-linked intellectual disability 94	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95677
VU 0364439	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82304
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6358
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066478
spleen_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.48437
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.956014
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01214
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.97203
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08388
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLOC-3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
IGF1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40118
trans-synaptic protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842309
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97295
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07061
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00189
MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911492
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45283
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.845993
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25543
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00923
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34116
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18394
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13095
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25826
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069882
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47673
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22219
KYSE410	CCLE Cell Line Gene CNV Profiles	1.0	2.58625
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08388
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26164
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51545
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45991
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65999
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97525
KPL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33737
Congenital stationary night blindness, type 1E	ClinVar Gene-Phenotype Associations	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888306
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.854673
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48325
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.83272
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.2264
GSE173873_8_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09549
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983138
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83518
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15219
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12072
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41642
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00787
Perturb_13258_KO_Pcgf3/Pcgf5_SRP115638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.13754
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.08356
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.957572
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70242
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23092
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8164
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059749
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70116
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
HUES64_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.926241
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.965692
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54697
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95906
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Hs-633T	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.81627
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52631
BLOC-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934873
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89157
ccsnb	GeneRIF Biological Term Annotations	1.0	null
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3757
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2592
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994345
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30173
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50929
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.890157
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27917
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Severe Myopia	DisGeNET Gene-Disease Associations	1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50136
SKES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59679
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840517
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15774
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.934325
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50485
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.91102
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29057
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71564
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28092
abnormal cone electrophysiology	MPO Gene-Phenotype Associations	1.0	null
maturity-onset diabetes of the young type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21585
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34926
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66361
cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.229888
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51589
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923318
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30432
Perturb_4844_KO_Hoxd12_SRP307505	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.12571
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54663
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88018
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
cos-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.545739
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986738
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
presynaptic cytoskeletal matrix assembled at active zones	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.596014
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915485
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02863
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00156
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903729
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71734
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3821
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39383
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937935
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23395
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42378
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18985
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893627
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43316
NCIH2030	CCLE Cell Line Gene CNV Profiles	1.0	1.41718
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2701
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39627
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64087
NB7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39487
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27329
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-394-ZBTB25_ZBTB25	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Pup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838746
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9324
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887546
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73998
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953417
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1184	CCLE Cell Line Gene CNV Profiles	1.0	1.3974
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067267
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85962
globe disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926693
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885193
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18143
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4476
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91129
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922695
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76072
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9387
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89181
Central amygdalar nucleus, capsular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03165
EDEM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33318
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60632
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DMAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10289
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.75
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862546
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09671
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0564
allelic	GeneRIF Biological Term Annotations	1.0	null
Amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16912
GUCA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81151
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8973
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89047
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57358
PPP1R16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64018
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75433
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11838
Complete Congenital Stationary Night Blindness	DisGeNET Gene-Disease Associations	1.0	null
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87404
H3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44888
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39822
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830485
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04834
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
GFPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70589
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82343
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862833
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49059
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52265
membrane part	GO Cellular Component Annotations 2015	1.0	null
abnormal eye physiology	MPO Gene-Phenotype Associations	1.0	null
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C8orf33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63478
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66148
Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77459
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1767
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39117
Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
superficial layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48368
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938641
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01632
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.93892
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38103
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21944
ITPRIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8571
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2194
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.43236
GTF3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45707
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851724
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.987742
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17271
stationary	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-436	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.35127
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Developmental and epileptic encephalopathy 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
SRSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
x-linked inheritance	HPO Gene-Disease Associations	1.0	null
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12559
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17979
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11004
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78491
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC35B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34995
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57832
UOK101	DepMap CRISPR Gene Dependency	1.0	3.11495
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54875
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04214
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978815
DAZAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89667
HOMER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61323
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3825
hsa-miR-4768-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34051
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.91954
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02198
BLOC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.894
PHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79858
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49345
OS-RC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OE33	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43062
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF696	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.339
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RQ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98905
eye disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38524
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01824
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922353
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26694
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.58668
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08388
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62894
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43215
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824899
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860223
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2682
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45221
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.21478
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41729
Olanzapine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20321
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15485
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73681
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37785
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.901973
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1869
GSE148252_2_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05765
ZINC8945	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94504
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02051
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.838016
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36152
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49245
TNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07636
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24402
Postsynaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
hsa-miR-4483	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11208
ZNF420	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4021
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882552
GFPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44816
Charcot-Marie-Tooth disease type 4K	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.021
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.79499
IFITM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47364
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.823175
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974518
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1990	DepMap CRISPR Gene Dependency	1.0	3.1185
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.657704
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84265
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14915
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.75747
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
DMS-273	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.91178
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60481
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829086
NB7	DepMap CRISPR Gene Dependency	1.0	5.27493
POLR2A	ENCODE Transcription Factor Targets	1.0	null
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22603
hsa-miR-371-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888924
superficial stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54253
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18143
ZNF396	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75907
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0284
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.34167
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11025
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969277
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79642
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77445
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.892004
abnormal rod electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.4836
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10596
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06807
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35179
hsa-miR-4640-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.899957
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916876
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.015
ZBED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17169
FASTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20835
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50359
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4957
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36211
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02863
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46222
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08388
KDM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56879
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32192
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965977
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25618
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955489
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03538
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04663
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35008
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26493
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67777
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941803
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50424
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65349
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11803
Enhanced S-cone syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.062107
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18132
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45431
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30207
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1185
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957432
Brain Lower Grade Glioma_LGG_TCGA-EZ-7264-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.341272
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.174
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38584
GTEX-OIZH-3026-SM-3NB1G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869637
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11572
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73776
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01295
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65407
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14977
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22423
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	1.59488
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1079
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27918
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01419
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
FKBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08249
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.99946
single-organism process	GO Biological Process Annotations 2015	1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
Retinoschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
ADD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27138
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830603
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87281
Cone-Rod Synaptic Disorder, Congenital Nonprogressive	DisGeNET Gene-Disease Associations	1.0	null
TBC1D16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32665
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99372
magnocellular diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.70643
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11452
Pepstatin A	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75788
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3267
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15267
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81846
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13403
ZC3H7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72091
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14258
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.45041
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32079
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.572
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22944
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
RGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79364
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45215
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01506
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM63A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31952
hsa-miR-4436b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13903
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8094
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843327
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81765
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0343
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63959
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nfe2l2_23639809_whole_esophagus_lof_mouse_gpl7202_gse39629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.70154
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18387
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80633
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49374
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.5787
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Aland Island eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935375
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832486
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867121
TSC1_Deficiency_GDS4572_347_mouse_Naive CD8 T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BHT101	DepMap CRISPR Gene Dependency	1.0	2.47641
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3189
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51108
Anterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95183
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7618
Cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
RAB35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.756
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01364
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47228
MTERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07512
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6591
TRAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69222
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51431
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01139
gonosomal inheritance	HPO Gene-Disease Associations	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11217
Perturb_3046_KO_Smarcd3_SRP044338	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.02157
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55223
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922533
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49156
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03538
Leber congenital amaurosis 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58835
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885632
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17385
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.052
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Kdm1a_KD_GDS5055_275_mouse_3T3-L1 preadipocytes - 48h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969725
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.568
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28295
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72776
Partial central choroid dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27138
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
maturity-onset diabetes of the young	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
A172	DepMap CRISPR Gene Dependency	1.0	2.37739
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09214
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25874
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855107
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75547
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7643
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03596
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75665
COA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19431
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925572
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75776
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.14
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28725
ELF5	ChEA Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58159
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890671
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1951
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23948
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93939
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2736
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842691
CSDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95695
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95233
mantle zone of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18716
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34288
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_16610_KO_Phb_SRP229743	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
RUNX3	ENCODE Transcription Factor Targets	1.0	null
Orphan GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959607
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62743
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14121
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82621
polymorph layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3165
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.926
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828534
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27227
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59208
myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.531928
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22954
night blindness	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09512
photoreceptor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328262
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52231
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.994295
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828269
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69648
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arciform density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9514
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07716
SARS-CoV MA15_Day2-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.13392
Cysmethynil	DeepCoverMOA Drug Mechanisms of Action	1.0	0.45
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.22203
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00688
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25459
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02173
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19149
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23089
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44166
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04005
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13852
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0013
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53824
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01991
UBB_KO_GDS3906_496_mouse_Testis -  28 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844791
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879891
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.49646
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26218
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.57045
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
NS309	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20623
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9274
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
GLUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77879
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.05081
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1293	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
RNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57266
hsa-miR-4780	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35128
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
PR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06462
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74304
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22555
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5844
GSE173873_12_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97275
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72383
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15582
Kidney Chromophobe_KICH_TCGA-KM-8442-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.13156
Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
Perturb_3325_KO_Tkt_SRP364774	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.75373
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32591
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21547
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49644
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59273
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903618
PDX1	JASPAR Predicted Transcription Factor Targets	1.0	null
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18705
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.102
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.983958
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03272
Lung squamous cell carcinoma_LUSC_TCGA-77-8009-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.117457
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23087
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56132
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891935
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46102
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43437
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974518
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital stationary night blindness	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09537
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6478-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37553
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11566893-13062_2024_564_MOESM1_ESM.docx-0-GLI3_GLI3	Rummagene Transcription Factor Associations 2026	1.0	null
NB-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0306
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50755
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960635
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866745
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88011
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00066
Perturb_4587_KO_Socs3_SRP074146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.87978
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.4988
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54324
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91359
GSE163052,GSE163198_1_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.145
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00354
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05161
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1825
GSE173873_8_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91859
ILF2_02_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.34792
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50303
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28399
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65168
KDM4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37813
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88461
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.61651
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	1.0	0.986328
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857743
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19406
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41053
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SYT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49344
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03812
Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.91054
C1orf198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93591
SP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46589
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22222
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13599
SETD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16358
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93552
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905737
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4096
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6181
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97087
Cone dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15427
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.916096
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0519
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3065
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835579
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.316
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.48083
GTEX-S7PM-0426-SM-3NM91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87866
Congenital nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24178
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34979
XRCC5_02_114	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.97728
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86119
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
sequencing	GeneRIF Biological Term Annotations	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.925288
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871592
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041852
Lung squamous cell carcinoma_LUSC_TCGA-58-A46M-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
congenital stationary night blindness	HPO Gene-Disease Associations	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07307
Night blindness	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18328
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42447
PFDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.33386
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923347
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.9696
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0858
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7765
MEIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18854
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994345
SRSF7_02_133	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.61471
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
chr17_38359708_C_T_b38	GTEx eQTL 2025	1.0	1.90287
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04123
IZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895488
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57872
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BCL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2518
dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.15776
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08632
Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36921
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70078
KP-3	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.74783
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	1.39276
HCC2998	DepMap CRISPR Gene Dependency	1.0	2.49463
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53048
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12084
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
hsa-miR-198	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998627
RBMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10183
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39506
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35243
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9391
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836365
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.80297
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47363
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3705
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32437
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Nance-Horan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20226
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00767
FDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51647
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.903
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37888
EP300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9591
PK1	CCLE Cell Line Gene CNV Profiles	1.0	1.54506
Reduced Visual Acuity	DisGeNET Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5367-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
NFE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38542
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29446
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938516
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23087
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TCEANC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14988
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11876
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871675
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9569
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79613
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.638676
vitamin c_mus musculus_gpl6246_gse19378	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22275
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2759
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hel	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
AP3M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44075
Odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86122
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99361
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4028
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04142
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.39269
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.959385
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72493
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7118
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42291
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1332
ALDH1A2_KO_GDS4836_290_mouse_anterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978319
bj	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837909
ZNF160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13897
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30845
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9786
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28511
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88335
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28725
Lung squamous cell carcinoma_LUSC_TCGA-21-1080-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19178
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3792
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02226
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.13611
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.917009
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.42734
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.613
MTF2	ChEA Transcription Factor Targets	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863545
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950325
Cone cell pedicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.9
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0555
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174383_4_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H510A	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.77515
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
abnormality of vision	HPO Gene-Disease Associations	1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
HCC827GR5	DepMap CRISPR Gene Dependency	1.0	2.3793
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18347
KE-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3262
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15719
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7818
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92953
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fundus albipunctatus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.941
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69918
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37716
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917963
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835777
COA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10489
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92783
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998921
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963138
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67878
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Eye-retinal bipolar neuron	Tabula Sapiens Gene-Cell Associations	1.0	0.744886
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5339
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25637
BL3800 (PALB2)	NURSA Protein Complexes	1.0	null
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58718
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16385
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44048
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30301
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.50538
SPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26851
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.372
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01338
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952039
KMM1	DepMap CRISPR Gene Dependency	1.0	3.06836
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98274
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.811001
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37313
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92673
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35821
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22942
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43003
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60495
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4108
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26599
Retinitis pigmentosa 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900287
OE33	CCLE Cell Line Gene CNV Profiles	1.0	2.3676
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20501
Peroxisomal importomer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
HELA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
TGM2_KD_GSE23702_713_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	2.15174
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76716
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31315
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptic cleft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.23
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823998
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88536
Anterior amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00554
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32868
KLRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9212
Hyalocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5168
DMXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13918
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21504
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3736
biological regulation	GO Biological Process Annotations 2015	1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938108
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3677-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12559
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R9-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47798
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Somatodendritic compartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P12-ICHIKAWA	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.78914
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20229
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75709
mode of inheritance	HPO Gene-Disease Associations	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24402
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3945
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30907
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21867
Perturb_14529_KO_Gata4/Nr5a2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.5097
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10573
Central retinal artery occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.025
Cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2095
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27275
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02329
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24293
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	1.0	0.934219
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34311
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30114
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42709
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18366
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48277
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75533
B3GNT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23607
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046823
697	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF383	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74839
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881331
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.948269
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22782
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.897559
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47843
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27844
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616586
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99377
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97516
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73432
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.87
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33228
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6189
tectal gray formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07941
Perturb_7329_OE_MOV10_SRP120600	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.52004
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
AP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62321
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10037
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02403
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60523
cone-rod dystrophy 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28516
GSE126504_0_v_1_hpse_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34624
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057166
system process	GO Biological Process Annotations 2015	1.0	null
C19orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10456
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24907
posteroventral (inferior) parietal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00148
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
FYCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98122
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855678
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11121
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07042
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46005
Huntington's disease-like 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51116
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826793
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Perturb_16513_KD_C11orf53_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.2524
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74883
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31577
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
METTL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41421
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8466
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844545
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6947
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.8288
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5117
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ZR-75-30	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17812
UMRC3	DepMap CRISPR Gene Dependency	1.0	2.23609
molecular_function	GO Molecular Function Annotations 2015	1.0	null
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48925
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879891
BNIP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49539
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2972
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24414
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	2.22984
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.938079
GSE111247_11_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
cell part	GO Cellular Component Annotations 2015	1.0	null
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.24637
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8492
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10776
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52203
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76846
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35115
Familial partial lipodystrophy type 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19252
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM278	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.34961
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899193
TMED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55973
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01505
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912589
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PL45	CCLE Cell Line Gene CNV Profiles	1.0	1.40103
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905211
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961768
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06155
LMNB2_02_191	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.67807
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90119
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14369
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU-475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04148
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.548
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.947219
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60353
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3825
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901501
STXBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78572
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08678
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48718
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17434
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	1.53355
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.86301
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16724
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91171
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35243
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885846
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850611
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Lung adenocarcinoma_LUAD_TCGA-MP-A4T9-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TULP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17944
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846329
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67737
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.831465
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28725
Ocular hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal cone electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.72811
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tideglusib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856486
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5205
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC316	DepMap CRISPR Gene Dependency	1.0	2.22465
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95115
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982646
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71391
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08267
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909309
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11142
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46839
Congenital stationary night blindness 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.655
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88777
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66145
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21539
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
ZSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72208
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22852
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6795
Neurodegeneration with brain iron accumulation 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05241
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71114
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87194
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.841221
MAN2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49433
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11263
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18213
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
BICR10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51205
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12069
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.68
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20872
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ENTREP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43801
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1727
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8727
Eye disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0268
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.8097
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r1 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18808
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20491
hsa-miR-3978	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09671
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41094
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41998
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894377
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22883
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-491-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
KP1N	DepMap CRISPR Gene Dependency	1.0	2.24141
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.301797
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70616
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827321
PMC12347849-mmc1.pdf-3-ENSG00000118526_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.958616
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64204
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28399
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82794
SLC25A36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25371
hsa-miR-2117	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20556
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860223
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22288
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860223
Fog2_KO_GDS3659_152_mouse_adult heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67109
BL-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10324
NFE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44945
CRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19629
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75113
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69669
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69872
HCC202	CCLE Cell Line Gene CNV Profiles	1.0	1.8222
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
visual perception	GO Biological Process Annotations 2015	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
KDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75817
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18956
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53728
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67939
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89449
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.97326
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907467
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30925
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08366
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19271
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23137
DOHH-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.60885
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02125
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.99299
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20123
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976375
sensory perception	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01495
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79261
Kdm1a_KD_GDS5055_274_mouse_3T3-L1 preadipocytes - 24h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19834
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.21858
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30239
LN18	DepMap CRISPR Gene Dependency	1.0	2.13216
PSMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48432
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68148
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060062
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06807
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.904481
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35159
KARPAS-422	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.51373
MATN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7002
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38538
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23005
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988472
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34576
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90345
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10585
abnormal conjugate eye movement	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830527
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28655
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C5-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77042
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0103
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
additional	GeneRIF Biological Term Annotations	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01497
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63719
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21364
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38708
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25943
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87173
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79498
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866194
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37547
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978704
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21761
TPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86611
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21554
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86873
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.20313
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873705
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48144
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837524
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24481
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61367
Telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.542
ATF3_02_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
EVSAT	DepMap CRISPR Gene Dependency	1.0	2.48228
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30173
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935226
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33763
BT474	CCLE Cell Line Gene CNV Profiles	1.0	3.27752
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.999967
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879891
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831446
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ARF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72964
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95577
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70051
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37955
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08814
Lung adenocarcinoma_LUAD_TCGA-44-A4SS-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
C16orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00585
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21561
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41141
AOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04487
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8941
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70368
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21976
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.908381
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30742
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81914
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32113
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05165
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.937496
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85715
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80169
TCF7	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45079
SIMA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42474
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84176
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0565
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43359
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958572
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838616
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5009
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
TRIM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45426
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00554
Terbinafine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
RFX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.941
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42604
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66959
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890955
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2249
sensory perception of light stimulus	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32581
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30399
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.69889
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12742
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Congenital stationary night blindness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413151
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843579
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04745
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76629
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17486
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89758
Lung adenocarcinoma_LUAD_TCGA-62-A472-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53059
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79801
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01083
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61916
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853279
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.6755
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09527
GAK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAMK2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37569
DLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42271
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55971
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06556
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ibrutinib1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.51
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45068
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91811
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17782
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7143-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.24117
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43007
EFNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83218
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
GTEX-TKQ1-1226-SM-4GICJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.4226
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49017
AHRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96819
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.006
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.118
EKC/KEOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW626	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEL-HO	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.03157
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35543
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38115
Neuronal ceroid lipofuscinosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
ZCCHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15294
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
hsf1_19179333_rko_colon_carcinoma_lof_human_gpl6244_gse12762	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.030454
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875902
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48622
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.102
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878039
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857222
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
PMC10039511-12864_2023_9238_MOESM1_ESM.xlsx-LPS_group-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.969013
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24502
GTEX-PWOO-2226-SM-2S1P1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879437
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09529
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGOLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59612
Congenital diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79533
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63819
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.048
NUDT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44632
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50749
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44036
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8068
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882167
vision/eye phenotype	MPO Gene-Phenotype Associations	1.0	null
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21025
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898624
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03171
presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.568001
Arrhythmogenic right ventricular dysplasia 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53748
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14939
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9777
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66389
ZFHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59123
NB14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hereditary night blindness	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
697	DepMap CRISPR Gene Dependency	1.0	3.80105
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.268
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35533
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4864
OVMIU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77443
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25858
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16142
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54082
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84451
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19045
VCPKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84921
Lung adenocarcinoma_LUAD_TCGA-05-4244-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15626
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5272
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247079
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826306
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98235
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.2048
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58578
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.564
ACTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54897
KLHL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41525
SIX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00851
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33656
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5815
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3836
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00668
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Posterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
REXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02424
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.151
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32628
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.888712
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86261
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47017
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15712_KD_Ctcf_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.83829
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9507
MITF	ChEA Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860197
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.942412
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55461
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07764
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06907
cone-rod dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
USP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14418
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVCA420	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00224
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital diarrhea 7 with exudative enteropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.321
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16451
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99977
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39414
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00992
Postsynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2108
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50385
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46554
GPSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47739
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11638
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51393
GSE199189_1_v_0_creld2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Epidermal growth factor-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3794
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88158
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54682
PFSK1	DepMap CRISPR Gene Dependency	1.0	4.20152
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50547
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5135
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Perturb_12142_KO_Lgals9_ERP122370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.79191
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	3.11566
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
TCEAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36158
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.2984
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7997
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979386
POU5F1	ChEA Transcription Factor Targets	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58996
CLASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81809
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28587
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81609
Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OE33	DepMap CRISPR Gene Dependency	1.0	4.85104
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44618
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
hsa-miR-943	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.94232
CHEMBL383736	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BZW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74832
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11541
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37157
hsa-miR-3614-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54541
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_118_KD_Fto_SRP314220	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.86
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.954637
anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43388
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6228-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1568	DepMap CRISPR Gene Dependency	1.0	2.13365
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0891
night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.16602
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13067
X- Linked Recessive	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10414
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10583
muscle	GTEx Tissue Gene Expression Profiles	1.0	0.874853
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHMAC5	DepMap CRISPR Gene Dependency	1.0	2.13552
SEC22C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95628
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19294
Nyctalopia	DisGeNET Gene-Disease Associations	1.0	null
PMC11952327-media-1.pdf-1-FOXD4L1_FOXD4L1	Rummagene Transcription Factor Associations 2026	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29812
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39043
PMC5094751__F12	PFOCR Pathway Figure Associations 2023	1.0	null
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87919
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24799
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19381
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1793
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21449
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9245_KO_Lin28a_SRP300815	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18793
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.2283
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00899
TBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97618
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2838
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.844494
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01386
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863545
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35482