association	dataset	threshold value	standardized value
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83862
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11741
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92902
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828825
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49345
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5432
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
increased food intake	MPO Gene-Phenotype Associations	1.0	null
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88918
NCIH1915	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55774
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
TBP	ENCODE Transcription Factor Targets	1.0	null
MKN74	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08341
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959531
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854878
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18679
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05896
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97522
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7621
IM9	DepMap CRISPR Gene Dependency	1.0	2.16107
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00166
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06893
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97602
HDAC1	ENCODE Transcription Factor Targets	1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23054
hsa-miR-3121-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32265
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93358
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26027
hsa-miR-4780	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110802_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
KATOIII	CCLE Cell Line Gene CNV Profiles	1.0	3.26636
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-2.52829
r5 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52424
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828859
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916718
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951816
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.14128
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30774
BACH1	ENCODE Transcription Factor Targets	1.0	null
JAR	DepMap CRISPR Gene Dependency	1.0	2.28205
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9278
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.7787
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47939
brain	GTEx Tissue Gene Expression Profiles	1.0	1.82787
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47342
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08019
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80791
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal glucose homeostasis	MPO Gene-Phenotype Associations	1.0	null
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22346
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12744
hsa-miR-106a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32868
hsa-miR-361-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
PMC10684515-41467_2023_43264_MOESM7_ESM.xlsx-HOXA9_ChIP-seq_peaks_in_SEM-Closest_Gene_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8585
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.910445
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC39A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69703
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69879
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8302
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
MB21D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65918
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920563
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13393
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93201
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55048
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928578
HTR1A	Pathway Commons Protein-Protein Interactions	1.0	null
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32092
PRDM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38787
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22176
hsa-miR-4701-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42793
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11926
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80724
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RALGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29013
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43436
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7505
LMO2	ChEA Transcription Factor Targets	1.0	null
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26129
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.956
GTEX-RU72-0826-SM-46MUS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825722
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21318
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2904
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53822
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09003
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
Pleated septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.217
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97321
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.57907
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870421
ZNF346	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40442
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2479
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16476
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06364
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
DB	CCLE Cell Line Gene Expression Profiles	1.0	1.40779
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57027
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4263	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891565
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040048
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Hepcidin/ferritin ratio	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40365
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6267
THAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54927
hsa-miR-577	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03246
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.861728
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60992
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83222
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52622
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21913
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38159
adipose tissue phenotype	MPO Gene-Phenotype Associations	1.0	null
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31037
Posterior nuclear complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
Pulvinar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
MOGGUVW	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23161
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HERPUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30907
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13152
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45099
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
Acute Myeloid Leukemia_LAML_TCGA-AB-2828-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brodmann area 36	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.5691
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SULT4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11833
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20748
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87494
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-331-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
SLC24A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08084
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35105
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21762
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.38897
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27646
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.5804
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
MYC	ChEA Transcription Factor Targets	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3188	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
indicator	GeneRIF Biological Term Annotations	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96251
RAB11FIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.433
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5103
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6985
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59752
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Melanoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
hsa-miR-1237	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
STON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89636
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1694	CCLE Cell Line Gene Expression Profiles	1.0	2.40893
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9334
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12014
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ERGIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75805
abnormal circulating lipid level	MPO Gene-Phenotype Associations	1.0	null
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87314
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79379
HEC50B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90135
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08884
KS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52739
hsa-miR-17	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Ventral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33999
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31781
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23254
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.17076
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89653
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08931
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4531	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86324
TCF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6617
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Gemcitabine-induced early high-grade neutropenia in pancreatic cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
KATOIII	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78214
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29118
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22411
MOLM6	CCLE Cell Line Gene CNV Profiles	1.0	1.35679
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83617
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6479
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86287
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891117
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.885
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29059
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CLPP_KO_GSE40207_378_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29811
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71298
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04612
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08909
HBQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09713
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-34b	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
NDUFB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63739
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1061
increased physiological sensitivity to xenobiotic	MPO Gene-Phenotype Associations	1.0	null
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43707
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69926
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028796
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21565
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35102
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840972
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19957
SCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21811
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.12878
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38701
BOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19253
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73381
FAM124A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67868
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42809
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
abnormal triglyceride level	MPO Gene-Phenotype Associations	1.0	null
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00833
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0858
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04162
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08348
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69161
abnormal glucose tolerance	MPO Gene-Phenotype Associations	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949813
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96938
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886413
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23012
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54821
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03466
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27264
SFXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97555
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7899
ZFC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77217
CLPP_KO_GDS4791_537_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MECO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UOK101	CCLE Cell Line Gene CNV Profiles	1.0	1.39462
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923979
REST	ENCODE Transcription Factor Targets	1.0	null
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
increased susceptibility to diet-induced obesity	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03718
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955962
Lung squamous cell carcinoma_LUSC_TCGA-66-2727-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15048
AKT1_OE_GDS2308[_473_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18767
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60408
HOP-92	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64875
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57354
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.96158
NDUFAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52454
Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167886_3_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65147
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868228
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02649
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865895
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03064
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50796
SAC3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55826
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02704
hsa-miR-632	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48221
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.02003
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825286
hsa-miR-522	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993952
Perturb_4722_KO_Smarcc1/Smarcc2_SRP124677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.09264
ZXDB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3922
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01097
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50546
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98674
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24291
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7983
GSE101239_3_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96607
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30726
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898059
hsa-miR-4446-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95412
increased circulating triglyceride level	MGI Mouse Phenotype Associations 2023	1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	10.789
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16858
hsa-miR-4292	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
Perturb_16102_KO_Map3k12_SRP157873	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.9317
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50493
DOV13	DepMap CRISPR Gene Dependency	1.0	2.23025
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79454
RBM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6727
DENND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62109
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE201520_8_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bilateral frontoparietal polymicrogyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42077
medial part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23877
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4995
SW948	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72482
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76446
PMC10280803-1415-4757-GMB-46-2-e20220358-s3.pdf-7003-NR1D2_NR1D2	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53046
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77648
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62002
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55205
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	150.889
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35236
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0706
Usher syndrome type 2C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.16743
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32299
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21804
DPP3_OE_GDS2653_650_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0046
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73995
Autosomal dominant nonsyndromic deafness 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18734
ACP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85563
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16861
Motion sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.689
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-514b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07118
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59495
U178	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32554
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.237
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36172
all	GWASdb SNP-Phenotype Associations	1.0	0.028772
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74806
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZCWPW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36283
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C21orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30445
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880429
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65476
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09206
Agranular insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845293
PMC9576445-IJG2022-9264555.nxml--Potential_targets_of_hsa-miR-15b-5p_AND_hsa-miR-16-5p_NOT_hsa-miR-184_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80865
SMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30763
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19099
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949813
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9712
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844844
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Papillary transitional carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8748
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0649
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94086
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11171
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
liminal part of r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02761
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3066
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47005
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906883
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
calcitriol_homo sapiens_gpl570_gse35925	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.380739
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86138
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21819
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16112
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70561
CLPP_KO_GSE40207_392_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-3940-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hsa-miR-4692	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
UBE2O	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8098
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.96029
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.135142
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30567
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89181
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54638
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	200.205
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94929
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057974
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64582
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-515-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94692
increased triglyceride level	MPO Gene-Phenotype Associations	1.0	null
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45098
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03254
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70785
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54632
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34728
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70375
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.34711
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.68365
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00107
abnormal physiological response to xenobiotic	MPO Gene-Phenotype Associations	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06906
hsa-miR-4782-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7993
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68173
SNU601	DepMap CRISPR Gene Dependency	1.0	5.30437
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07899
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39183
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12429
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825286
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824461
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
gliomas	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-409-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09479
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RD	DepMap CRISPR Gene Dependency	1.0	4.62616
Laterodorsal thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1573
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30248
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39368
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11705
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07349
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
Perturb_16882_KO_Pin1_SRP051514	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.789
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.980869
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH526	DepMap CRISPR Gene Dependency	1.0	7.325
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16521
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31027
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89544
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.508628
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10089
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98278
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
GTEX-TKQ2-0926-SM-4DXU5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871366
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51212
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
DNASE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70778
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01646
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71152
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840613
PMC11951737-12974_2025_3417_MOESM6_ESM.xlsx-Sheet5-CREB_Signaling_Pathway_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55379
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27031
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51668
LCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67369
hsa-miR-3160-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
hsa-miR-4324	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
LDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84392
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4929
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85115
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41661
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51241
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27333
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0726
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL3-CLOSEST_GENE_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44618
hsa-miR-3620	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027811
P30OHK	DepMap CRISPR Gene Dependency	1.0	2.13654
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38537
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52813
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93589
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.869259
hsa-miR-4708-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
hsa-miR-3617	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCC25	CCLE Cell Line Gene Expression Profiles	1.0	1.39516
PKP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85391
SNU398	CCLE Cell Line Gene CNV Profiles	1.0	1.42843
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6987
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54699
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.81832
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50054
RAD21	ENCODE Transcription Factor Targets	1.0	null
TGOLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59612
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3602
COL4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48606
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21949
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46021
RAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12917
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48736
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.135
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24322
suggesting	GeneRIF Biological Term Annotations	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18632
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70684
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15273
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.04237
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.6411
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.416
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RP-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal circulating hormone level	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878923
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer II of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972455
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45251
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33678
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.65113
TFEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63978
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65547
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-4471	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88211
Perturb_4144_KO_Bcl11a/Bcl11b_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.83374
ETS2_KD_GDS5040_129_human_H441	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05471
hsa-let-7b	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NS-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.844851
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32499
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02025
pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.157919
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3568
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.880388
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47552
bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.223853
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67671
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21574
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13355
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058619
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82857
h5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949813
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
intermediate stratum of 5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04377
hsa-miR-4490	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898464
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89102
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87622
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918763
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66846
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
PMC5503627-oncotarget-08-39497-s003.xlsx-hypo_in_shUHRF1_KD-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RAPGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95265
Perturb_8536_KD_Rbfox1/Rbfox3_SRP062242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.3382
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57684
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54189
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FCSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56702
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.85505
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25718
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53369
hsa-miR-3194-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88211
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.40628
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60532
MOLP8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82387
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIH1694	DepMap CRISPR Gene Dependency	1.0	2.28239
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.237
CYP2R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29977
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30346
BICR56	DepMap CRISPR Gene Dependency	1.0	2.36436
TPBGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26607
IRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17794
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08616
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.892828
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.0132
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931013
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nd7/23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30875
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14734
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27592
ARNT	ChEA Transcription Factor Targets	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3155
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74529
Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998763
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53671
Secondary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08211
hsa-miR-576-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
NCIH524	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72868
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57688
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05453
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4542
GSDMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17401
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16344
UBQLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40729
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34856
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86183
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20412
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49806
SLC25A27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90897
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18488
hsa-miR-3977	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
DSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6551
abnormal food intake	MPO Gene-Phenotype Associations	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33964
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.04831
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15559
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70632
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12476
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34314
IALM	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21038
hsa-miR-3647-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
hsa-let-7d	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
Monoclonal gammopathy of undetermined significance (MGUS)_Bone Marrow_GSE5900	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.72774
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25661
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75782
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CAOV4	DepMap CRISPR Gene Dependency	1.0	2.62428
increased circulating insulin level	MGI Mouse Phenotype Associations 2023	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41695
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52812
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852722
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02844
HCT116	CCLE Cell Line Gene CNV Profiles	1.0	1.43944
RPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97241
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06098
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35652
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88158
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.952794
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03954
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.85632
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38354
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28353
hsa-miR-526b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826412
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26411
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8014
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
H2BC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
hsa-miR-579	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34205
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ALDH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99777
increased circulating cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0588
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68167
behavioral despair	MPO Gene-Phenotype Associations	1.0	null
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89262
hsa-miR-3671	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46864
hsa-let-7a	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
Bony labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
CSDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95695
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.825
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2745
CTSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67338
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03686
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59769
20161705-Table2	GeneSigDB Published Gene Signatures	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2439
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83656
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58715
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
MAFK	ENCODE Transcription Factor Targets	1.0	null
SNU324	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4881
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2270_KO_lincBrn1b_SRP028547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
abnormal circulating ghrelin level	MPO Gene-Phenotype Associations	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO792	CCLE Cell Line Gene Expression Profiles	1.0	1.5836
endocrine pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.206913
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88499
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48337
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82539
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
increased thigmotaxis	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-519d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Motion sickness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.1
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92196
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23855
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14361
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76829
abnormal eating behavior	MPO Gene-Phenotype Associations	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6341
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51264
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49455
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13809
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9912
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859895
Adult body size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16903
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00661
hsa-miR-190b	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05939
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.11499
TP53-18474530-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3927	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91153
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50314
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99797
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15127
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05071
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6182
SU8686	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66416
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60813
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
increased total body fat amount	MGI Mouse Phenotype Associations 2023	1.0	null
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23845
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JB-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal energy homeostasis	MPO Gene-Phenotype Associations	1.0	null
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04954
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12366
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25641
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	228.812
ETS2_KD_GDS5040_9_human_H441 lung cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31781
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35489
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072928
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01316
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.955769
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0448
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
SUM229PE	DepMap CRISPR Gene Dependency	1.0	2.98524
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04669
ABCF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58469
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C84	DepMap CRISPR Gene Dependency	1.0	5.8045
LN18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90661
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050255
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.79998
H3K9me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46827
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.92852
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15846
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32401
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6599
ischemic bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.823308
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	2.27945
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
silencing	GeneRIF Biological Term Annotations	1.0	null
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44269
alcohol preference	MPO Gene-Phenotype Associations	1.0	null
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32358
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21469
STAT3	ChEA Transcription Factor Targets	1.0	null
mantle zone of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02761
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03677
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54784
Trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70213
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21913
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.965503
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57568
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31379
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42631
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29155
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28463
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46661
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058012
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66037
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65954
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69238
increased anxiety-related response	MPO Gene-Phenotype Associations	1.0	null
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66693
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15364
HEY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75274
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35236
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09775
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40431
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08395
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040353
Prostate adenocarcinoma_PRAD_TCGA-SU-A7E7-01A-22R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.827119
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956854
Thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.421
HUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28316
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9257
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19507
hsa-miR-4639-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04474
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42748
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89544
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
Brain Lower Grade Glioma_LGG_TCGA-HT-A616-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973178
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99654
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05792
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
CC2D1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63004
YAP1	ChEA Transcription Factor Targets	1.0	null
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
TMEM97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.002
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
PACADD161	DepMap CRISPR Gene Dependency	1.0	5.0512
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13605
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66148
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04415
hsa-miR-487a	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
hsa-miR-3144-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
abnormal fear/anxiety-related behavior	MPO Gene-Phenotype Associations	1.0	null
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6745
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17289
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04772
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.922427
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38139
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844374
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56337
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82524
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94431
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47394
AHSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22147
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936568
BT20	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23423
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-380-ZNF584_ZNF584	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36122
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878438
abnormal depression-related behavior	MPO Gene-Phenotype Associations	1.0	null
CHK2_KD_GSE54268_668_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54145
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82469
TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38331
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53875
SIN3A	ENCODE Transcription Factor Targets	1.0	null
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81222
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45878
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11127
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47025
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
FZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58912
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46293
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6847
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99215
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.1745
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
hsa-miR-4251	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
SNU410	DepMap CRISPR Gene Dependency	1.0	2.04306
hsa-miR-142-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
NAMALWA	CCLE Cell Line Gene Expression Profiles	1.0	1.67188
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
HADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36372
hsa-miR-501-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
TPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62728
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11799605-jomes-34-1-65-supple.pdf-12-RARB_RARB	Rummagene Transcription Factor Associations 2026	1.0	null
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NEU3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2469
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66013
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79393
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48855
Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39423
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91376
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08002
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950457
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54165
FOXP3_ABLATION_GDS2525_64_mouse_mature regulatory T cells (Treg)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45826
NCIH524	CCLE Cell Line Gene Expression Profiles	1.0	1.74362
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46343
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863145
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87175
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38444
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.30332
RUNX1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847136
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92334
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16835
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.74836
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949813
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.37336
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
hsa-miR-1246	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10018
KASUMI1	CCLE Cell Line Gene CNV Profiles	1.0	1.37438
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_28_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60424
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14725
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07885
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67965
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7621
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891118
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04089
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2035
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal circulating insulin level	MPO Gene-Phenotype Associations	1.0	null
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_3Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.20259
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	87.2715
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80036
suppressor	GeneRIF Biological Term Annotations	1.0	null
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95105
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94761
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048774
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55612
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22071
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.957823
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56096
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.484
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99235
primary	GeneRIF Biological Term Annotations	1.0	null
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.89284
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49303
hsa-miR-4288	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
nucleotide-excision repair factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.482
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78058
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93574
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.242
decreased energy expenditure	MPO Gene-Phenotype Associations	1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36581
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
SPCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26936
PHETA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99854
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6839
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02143
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15629
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42004
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85187
PMC10280803-1415-4757-GMB-46-2-e20220358-s3.pdf-7003-ENSG00000174738_NR1D2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal lipid homeostasis	MPO Gene-Phenotype Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02277
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040599
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9205
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16861
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16318
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.913016
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84452
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
TOV21G	CCLE Cell Line Gene CNV Profiles	1.0	1.53165
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55468
alcohol preference	MGI Mouse Phenotype Associations 2023	1.0	null
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45031
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053982
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69124
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
METTL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84721
glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.527676
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.994271
hsa-let-7f	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83797
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35093
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907792
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88274
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
ZBTB40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42044
GATA2	ChEA Transcription Factor Targets	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12441
WM983B	CCLE Cell Line Gene Expression Profiles	1.0	1.57881
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06776
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
SKMEL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32616
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93496
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal circulating triglyceride level	MPO Gene-Phenotype Associations	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985611
DLGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43227
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27305
Perturb_4147_KO_Bcl11a/Bcl11b_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal emotion/affect behavior	MPO Gene-Phenotype Associations	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11522
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06472
GJD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94398
PTPN1_KD_GSE54157_673_human_KM-H2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911813
Perturb_8601_KO_Pyk2_SRP285527	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.24828
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01299
MON	DepMap CRISPR Gene Dependency	1.0	2.17944
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03017
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856141
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53949
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.46988
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98595
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3223
TPSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15142
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9611
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8952
CHD7	ENCODE Transcription Factor Targets	1.0	null
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51886
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.639
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24131
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877618
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4055
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25223
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958065
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.340906
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03874
Cardiac Troponin-T levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4903
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20161705-Table4	GeneSigDB Published Gene Signatures	1.0	null
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01136
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90626
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.21274
abnormal cholesterol homeostasis	MPO Gene-Phenotype Associations	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3667-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1928
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05096
NDUFA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18045
YWHAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1702
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.41349
hsa-miR-4310	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48429
AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51246
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0693
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31623
ZNF655	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68124
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42332
brain	HPA Tissue Gene Expression Profiles	1.0	2.24804
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050202
Perturb_4471_KO_Prdm12_SRP334439	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.67179
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.521
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10443
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97421
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00903
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
middle frontal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844364
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07799
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33269
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
Vibratory urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
increased circulating leptin level	MPO Gene-Phenotype Associations	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053764
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89684
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11647
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1166
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97848
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09717
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15089
GTEX-UJHI-0926-SM-4IHKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908961
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.83282
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10742
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896669
abnormal body fat mass	MPO Gene-Phenotype Associations	1.0	null
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85879
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46858
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65895
CUEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20321
Rhomboid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6232
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
GSE149035_7_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02043
hsa-miR-4753-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
CORL311	CCLE Cell Line Gene Expression Profiles	1.0	1.84966
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.40025
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57152
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7346
YY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78275
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09183
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8339
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51244
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30069
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13344
USP17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78783
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9098
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32966
JJN3	DepMap CRISPR Gene Dependency	1.0	3.0935
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.968375
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19205
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27592
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82378
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7419
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11398
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18833
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20237
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.182
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.449
Malignant Glioma	DisGeNET Gene-Disease Associations	1.0	null
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38109
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intermediate reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03645
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47498
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.874326
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854088
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977796
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5269
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8106
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17975
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61452
hsa-let-7c	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99665
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50985
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63127
PRKAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64943
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45849
PAS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.319
abnormal circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44944
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04391
Lung squamous cell carcinoma_LUSC_TCGA-J1-A4AH-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95759
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	2.56089
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71691
hsa-miR-4474-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
H3K14ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
increased thigmotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	1.35631
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61871
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06413
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32808
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30439
frontal operculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827547
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7050-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38057
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53049
Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glioblastoma, Idh-Wildtype	DisGeNET Gene-Disease Associations	1.0	null
simultaneously	GeneRIF Biological Term Annotations	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1219
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040392
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	185.203
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68157
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77364
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050255
GSE169155_1_v_7_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55934
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856796
C8orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38236
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6492-01A-12R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1226	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.74884
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00918
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13471
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45521
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887213
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12327
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12144
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42898
PLS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.0277
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11168
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07186
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65181
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.0568
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7677
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.064188
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01442
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82309
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07077
CSTB_KO_GDS5089_565_mouse_cerebellum and granule neurons	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951349
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73995
Right lateral prefrontal cortical growth	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
NFKBIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8751
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859496
CYLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
TCF12	ENCODE Transcription Factor Targets	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNUC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51352
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43989
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15631
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824461
FIGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36137
NB6	DepMap CRISPR Gene Dependency	1.0	4.1768
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.70456
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51619
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
impaired glucose tolerance	MPO Gene-Phenotype Associations	1.0	null
GTEX-S33H-0726-SM-4AD6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03443
ETFRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8002
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85581
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977351
Cell septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12856
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95531
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4507	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56874
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81722
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26453
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05089
GTF2IRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31882
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8652
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.077
TAL1	ChEA Transcription Factor Targets	1.0	null
increased circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-190	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25459
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64626
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
hsa-miR-4459	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76724
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24276
SSTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42923
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26849
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941954
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4520a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Beare-Stevenson cutis gyrata syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838858
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2134
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4464	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
HTR1A-GPR26 complex	CORUM Protein Complexes	1.0	null
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-1260b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43155
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
ADCYAP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16251
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26179
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13356
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-421_ChIP-Seq_H3K9me1_2_AR_differential_expression_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48645
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02791
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.1347
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12222
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45199
MTF2	ChEA Transcription Factor Targets	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4724
CX-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
RAPGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68867
LYNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24591
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47462
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14937
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54279
hsa-miR-3713	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLPP_KO_GDS4791_104_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57261
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
hsa-miR-4652-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40155
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04382
kidney disease	GWASdb SNP-Disease Associations	1.0	0.844278
hsa-miR-1197	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.0319
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43984
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.9514
MCAS	CCLE Cell Line Gene CNV Profiles	1.0	1.59504
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00661
Lung squamous cell carcinoma_LUSC_TCGA-22-5473-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-331-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ZNF555	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56455
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.70099
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82175
biological regulation	GO Biological Process Annotations 2015	1.0	null
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850803
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	362.714
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896308
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCNB1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32531
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26086
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84247
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.7129
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C19orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3997
OVK18	CCLE Cell Line Gene CNV Profiles	1.0	1.46964
Intelligence	DisGeNET Gene-Phenotype Associations	1.0	null
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17038
ECC10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70801
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	296.647
hsa-miR-203	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61313
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933307
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13148
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44205
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2462
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21935
PMC5747948__F6	PFOCR Pathway Figure Associations 2024	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.43451
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64067
IFNLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61181
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
gpr26	GeneRIF Biological Term Annotations	1.0	null
PDIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4079
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1084
NMB	DepMap CRISPR Gene Dependency	1.0	4.13817
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	1.82822
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CFLAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26602
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875126
hsa-miR-4520b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
malignant	GeneRIF Biological Term Annotations	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.157919
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05362
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	225.197
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55748
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18577
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4742-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
increased anxiety-related response	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60448
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00154
Perturb_16513_KD_C11orf53_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5491
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36275
abnormal drinking behavior	MPO Gene-Phenotype Associations	1.0	null
CSTB_KO_GDS5090_198_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17109
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944898
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51158
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41459
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7749
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-4695-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38577
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4264
EIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38894
HSPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86257
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957105
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95311
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86822
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01288
myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.239799
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77852
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
adenylate cyclase-activating g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824488
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54066
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15274
abnormal adipose tissue morphology	MPO Gene-Phenotype Associations	1.0	null
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62024
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9352
PHF8	ENCODE Transcription Factor Targets	1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62024
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27928
tetraspanin-enriched microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
SUZ12	ChEA Transcription Factor Targets	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053407
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49887
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.908438
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31437
Lung squamous cell carcinoma_LUSC_TCGA-18-3409-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03317
EW16	DepMap CRISPR Gene Dependency	1.0	2.12045
MCOLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07621
ZC3HAV1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27834
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1519
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924928
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.02399
glioblastoma	GeneRIF Biological Term Annotations	1.0	null
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22194
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.16016
increased circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98166
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0996
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10355
Autosomal dominant nonsyndromic deafness 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
NMC-G1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55367
UMUC6	DepMap CRISPR Gene Dependency	1.0	4.42213
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7825356-8844261.f3.docx-48-IKZF5_IKZF5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22167
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15958
increased cholesterol level	MPO Gene-Phenotype Associations	1.0	null
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36761
HES3_KO_GSE64449_186_mouse_Min6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72143
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87066
preference for addictive substance	MPO Gene-Phenotype Associations	1.0	null
MAP3K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49255
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.28273
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
vacuole-mitochondrion membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37212
icSARS CoV_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.37818
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
HCV_8week-No IFN-a_None_GSE37715	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83188
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826967
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37564
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sirt1_OE_GDS2658_140_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13726
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981455
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ABHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17397
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54705
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27549
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45118
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62116
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13726
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11731
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25545
UROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81978
r4 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0196
TAF1	ENCODE Transcription Factor Targets	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.995187
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61593
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14688
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
liminal part of the r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02396
superior frontal gyrus, right, medial bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964027
TMEM30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57858
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-656	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35281
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858158
hsa-miR-106b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K9me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.909791
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PR-DUB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4416
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7551
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828391
caudal group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963852
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13175
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866398
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19099
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01934
hsa-miR-2278	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51518
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65048
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63871
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11888
r5 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02598
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.118569
CAMKK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2776
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994002
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923651
Lung squamous cell carcinoma_LUSC_TCGA-77-7141-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased energy expenditure	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_12547_KO_Shank2_SRP309197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.35566
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4008
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2827
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01349
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26719
PLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80943
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29384
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20099
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853113
hsa-miR-4253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0536
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12326
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41212
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68569
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18527
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3681	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-4514	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
DAGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64452
H3K27me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.68
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPVG-1326-SM-4B65P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845336
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00272
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12169532-pone.0325700.s010.xlsx-Table_S4-Table_S4_List_of_genes_that_upon_knockdown_KD_led_to_transcriptional_signitures_similar_to_the_input_DEG_set_of_CRC_or_LIHC_and_their_KEGG_enrichment_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11184788-40164_2024_526_MOESM4_ESM.xls-MSC-EV_proteins-Unnamed_4_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91282
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61565
BE2M17	DepMap CRISPR Gene Dependency	1.0	4.27273
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48829
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26848
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055235
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66199
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4693
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
ZNF416	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71222
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01295
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01352
hsa-miR-3136-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
HOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4231
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94678
IGFBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39662
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74611
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34179
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36396
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
ATXN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86719
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98147
NCIH650	DepMap CRISPR Gene Dependency	1.0	3.85137
CPCN	CCLE Cell Line Gene Expression Profiles	1.0	3.40829
PDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56251
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.40981
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96722
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925427
increased circulating leptin level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE149075_8_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3928	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55576
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38067
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.251
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97624
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0433
NDUFAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63265
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54429
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9264
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3352
L428	DepMap CRISPR Gene Dependency	1.0	2.92075
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
POLR2A	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.946723
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22374
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879957
LDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70549
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9425
SELENOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80613
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82985
KMCH1	DepMap CRISPR Gene Dependency	1.0	3.13819
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26017
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30294
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050706
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02067
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25907
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31329
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898059
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985586
CLPP_KO_GSE40207_388_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79003
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99483
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC1A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9803
A-172 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11155
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07958
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93313
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41982
NCIH1694	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91339
EIF2AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80688
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63388
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.889979
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42324
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51499
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00533
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00997
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4542
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14649
ZFYVE19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenylate cyclase-modulating g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3935	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-942	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
IMR32	CCLE Cell Line Gene Expression Profiles	1.0	1.97139
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00805
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047491
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00266
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.199785
hsa-miR-10a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE101112_0_v_2_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919855
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO679	DepMap CRISPR Gene Dependency	1.0	3.12964
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8874
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36294
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94831
RHOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91677
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16164
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10115
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
SMUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68887
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75031
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841889
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931433
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85294
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977796
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC74A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67881
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	1.7852
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
NB10	DepMap CRISPR Gene Dependency	1.0	3.27423
CPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6794
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	173.703
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19628
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838525
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24747
HMGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
FAM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41126
Brain Lower Grade Glioma_LGG_TCGA-DU-7309-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46492
Meniere's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36061
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
UMUC1	CCLE Cell Line Gene CNV Profiles	1.0	2.07609
Sensory dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906833
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92803
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.986184
PMC9630632-Table1.XLSX-diff_exp_genes-Group_2_vs_3_AND_Group_1_vs_3_NOT_Group_1_vs_2_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	1.53544
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39964
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82402
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85796
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30471
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966916
Perturb_13054_OE_HDAC4_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.90955
disease	GWASdb SNP-Disease Associations	1.0	0.024868
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-1926-SM-4DM6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03146
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845499
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06387
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64929
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14869
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G8-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CALU-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	2.00084
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894518
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837577
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0881
RAB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36701
hsa-miR-1305	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4088
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88296
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.03667
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85231
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930312
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64123
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64275
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04743
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52052
PMC5747948__F6	PFOCR Pathway Figure Associations 2023	1.0	null
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949813
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.0336
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953594
GSE108675_2_v_1_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10481
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
ITM2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73008
abnormal susceptibility to weight gain	MPO Gene-Phenotype Associations	1.0	null
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69499
hsa-miR-4644	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20237
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00381
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39011
Cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	2.00053
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60789
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.02708
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.602
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-1226-SM-46MUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86486
GTEX-XQ8I-1626-SM-4BOOI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844285
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922876
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.93935
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95001
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.7479
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26747
hsa-miR-4691-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
CHD1	ENCODE Transcription Factor Targets	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.237
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05294
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22176
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43808
Optic lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65767
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08029
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07459
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07588
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49891
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.11757
hsa-miR-1206	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983493
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864395
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81011
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39934
hsa-miR-4269	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-1248	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10037
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86333
abnormal behavioral response to xenobiotic	MPO Gene-Phenotype Associations	1.0	null
Amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4919
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02518
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949813
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82467
abnormal hormone level	MPO Gene-Phenotype Associations	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840293
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.24881
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.70099
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855912
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55429
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.08087
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-SOX14-sequence_name_SOX14	Rummagene Transcription Factor Associations 2026	1.0	null
MKI67	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72482
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21857
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
abnormal liquid preference	MPO Gene-Phenotype Associations	1.0	null
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0479
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26092
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-125a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41738
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03333
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6694
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-484	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	2.28259
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74119
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1286
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962332
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6389
Chronotype	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
hsa-miR-4278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
common	GeneRIF Biological Term Annotations	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	73.2467
SW626	DepMap CRISPR Gene Dependency	1.0	2.10224
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18852
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38294
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04295
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07543
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07799
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66904
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
impaired glucose tolerance	MGI Mouse Phenotype Associations 2023	1.0	null
MPT synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.929
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.4601
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03527
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SH-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10144
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84704
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal circulating leptin level	MPO Gene-Phenotype Associations	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00323
RBBP5	ENCODE Transcription Factor Targets	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23928
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09648
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07716
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92953
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.945062
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43279
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65795
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39712
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
Perturb_15744_KO_Cyp4v3_SRP358013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.02328
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11698
PMC3470785-NIHMS377161-supplement-12.pdf-886-ATF7_ATF7	Rummagene Transcription Factor Associations 2026	1.0	null
increased susceptibility to weight gain	MPO Gene-Phenotype Associations	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28587
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33165
SERPINB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98646
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958065
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
TRABD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69308
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66192
ETAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51151
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9349
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.61871
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72507
ZNF541	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39605
hsa-miR-4277	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
hsa-miR-136	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.942507
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882738
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87133
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849921
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19114
PLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65912
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
RERF-GC-1B	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3434
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2209
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09633
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12144
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68536
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42218
SNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56141
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45414
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89534
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52491
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23508
KPNYS	DepMap CRISPR Gene Dependency	1.0	2.9629
FMNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1481
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48425
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98114
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-202	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36399
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38893
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79642
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
Phagophore assembly site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.892
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07416
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72374
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41453
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
ZFHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53867
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10712
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09111
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05668
hsa-miR-591	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40938
Sin3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60435
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858002
MAX	ENCODE Transcription Factor Targets	1.0	null
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
ZDHHC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1614
KLRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01485
hsa-miR-4672	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Sarcoma_SARC_TCGA-WK-A8XO-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
hsa-let-7i	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31781
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2035
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23136
DNAJB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62685
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
genetic	GeneRIF Biological Term Annotations	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17413
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46262
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69776
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44755
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825286
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56868
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84828
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373118
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.002
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	2.65429
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
abnormal glucose homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
intermediate stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60532
LAMA84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59943
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76862
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44307
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.511
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25334
membrane	GO Cellular Component Annotations 2015	1.0	null
abnormal sterol level	MPO Gene-Phenotype Associations	1.0	null
Lateral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
Autosomal recessive nonsyndromic deafness 102	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.96209
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.922
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32675
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.52605
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829734
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26299
hsa-miR-3161	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20408
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_16720_Mut_Lmna_SRP309326	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.86231
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62494
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20012
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69445
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01665
hsa-miR-4799-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34351
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849589
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39994
increased circulating insulin level	MPO Gene-Phenotype Associations	1.0	null
C1QBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92318
GIMEN	DepMap CRISPR Gene Dependency	1.0	4.03093
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79108
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76349
H3K27me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-670	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.187113
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73784
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45098
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898059
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36204
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90697
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Trigeminal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26848
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41932
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.34461
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16433
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055373
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36015
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	79.332
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2806
behavioral despair	MGI Mouse Phenotype Associations 2023	1.0	null
Odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69798
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08835
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35414
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45426
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13283
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	191.01
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77234
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80119
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
RNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87482
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3736
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60988
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60532
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874138
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0246
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29914
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66828
hsa-miR-4760-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.6438
Dosage compensation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-20b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70663
KP2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71587
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-let-7g	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.04802
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29551
LRRC41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47236
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
TECPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20374
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
PLEKHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
Medial geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90108
HTATIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8938
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66042
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977796
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78362
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50865
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
IGLON5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44853
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897979
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33958
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894435
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31364
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36629
Cranial ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05512
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08319
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1214	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51634
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78639
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31968
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07332
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KCNK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00196
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.938367
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28369
r4 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02639
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82037
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58996
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32198
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52961
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.55262
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	2.63176
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	2.82174
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9641
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.715855
hsa-miR-338-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
Autosomal dominant nonsyndromic deafness 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98339
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.13018
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14601
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6966
hsa-miR-4748	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52767
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.926525
G protein-coupled receptor activity	GO Molecular Function Annotations 2023	1.0	null
BMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61466
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02962
Glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
CORL279	DepMap CRISPR Gene Dependency	1.0	6.43178
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64428
NCIH1436	CCLE Cell Line Gene CNV Profiles	1.0	1.53233
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881622
hsa-miR-4458	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6932
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
RNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28943
SNU668	CCLE Cell Line Gene Expression Profiles	1.0	1.41674
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44391
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53416
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02931
Perturb_8628_KO_Pyk2_SRP329328	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.65328
NPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65517
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14693
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32868
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53992
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.73564
increased sterol level	MPO Gene-Phenotype Associations	1.0	null
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78144
CCDC120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69524
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTDSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88443
CSTB_KO_GDS5089_169_mouse_Cerebrellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SLC39A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71676
CSTB_KO_GDS5089_486_mouse_Cerebellum and granule neurons	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.73801
NAXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30545
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-514	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95949
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7332
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72114
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2167
layer 1 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23741
hsa-miR-4306	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
KLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85734
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04274
hsa-miR-4533	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87012
CCNJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99564
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824416
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.237
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06923
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
GSTZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22583
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.30381
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64157
L-6 myoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07722
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83051
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-PHOX2B-fromNode_PHOX2B	Rummagene Transcription Factor Associations 2026	1.0	null
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
METTL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34888
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72328
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	181.771
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00289
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01331
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.1366
GSE215086_0_v_1_batf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98422
KLF7_KO_GDS2069_68_mouse_olfactory epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE218060_7_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852558
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898531
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5347
BT12	DepMap CRISPR Gene Dependency	1.0	3.70062
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11386
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.86073
GSE95685_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9914
abnormal energy expenditure	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4500	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.5676
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39332
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	164.153
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864441
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4176
NANOG	ENCODE Transcription Factor Targets	1.0	null
increased food intake	MGI Mouse Phenotype Associations 2023	1.0	null
GSE141667_3_v_2_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42947
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73
hsa-let-7e	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69445
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45338
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08796
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
hsa-miR-4716-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902344
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIV-1_LAI_12Hour-UV_treatment_None_GSE56484	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51663
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perirhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal alcohol consumption	MPO Gene-Phenotype Associations	1.0	null
Globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7302-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal cholesterol level	MPO Gene-Phenotype Associations	1.0	null
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33136
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21032
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882037
H3K9me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84002
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95299
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03775
RPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69344
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21851
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0024
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944502
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23641
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32813
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SPAST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85933
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940299
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
TRIM28	ChEA Transcription Factor Targets	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
A-CA-04-2009(H1N1)_0Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.52828
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04892
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06103
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24793
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94562
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01559
hsa-miR-548an	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04158
SOCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00165
GATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62177
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_17326_KO_Dis3_SRP328540	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.12933
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03254
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38055
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33825
LS123	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0885
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57051
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28893
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864593
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2396
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.263
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15941
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19107
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99942
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88968
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12203
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03584
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.591
RUNX1	ChEA Transcription Factor Targets	1.0	null
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15622
GTEX-V1D1-0326-SM-4JBIY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848274
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29126
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73586
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58101
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836623
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
hsa-miR-219-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79672
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36757
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28846
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1555
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76867
Ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
MYC	ENCODE Transcription Factor Targets	1.0	null
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52893
TCCPAN2	DepMap CRISPR Gene Dependency	1.0	4.1366
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	3.40474
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18399
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37286
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938139
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57961
UQCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67624
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-MB-A8JL-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEP131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20703
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051046
RNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92939
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61194
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65925
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30309
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ELF5	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.07728
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
NB17	DepMap CRISPR Gene Dependency	1.0	4.79646
MCIXC	DepMap CRISPR Gene Dependency	1.0	2.94946
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31551
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07939
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20983
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NDFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8045
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7601
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05096
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35121
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68429
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86241
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LYPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7027
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.95012
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5928-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0292
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68355
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03322
g-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	GO Biological Process Annotations 2015	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98332
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8025
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43109
UBE2S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00151
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02219
mgmt	GeneRIF Biological Term Annotations	1.0	null
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53604
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37124
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2442
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.32458
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38248
FAM83G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12199
hsa-miR-1229	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39219
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832606
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17486
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.738997
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41523
ETS2_KD_GSE43459_687_human_H441 lung cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47758
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08693
hsa-miR-4320	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36412
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68669
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897858
TOP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4309
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32327
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2901
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06472
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
blood vessel	GTEx Tissue Gene Expression Profiles	1.0	0.925632
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11458
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865969
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.890739
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976587
EDA2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54459
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
SCLC21H	CCLE Cell Line Gene Expression Profiles	1.0	1.90628
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48957
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10668
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41124
hsa-miR-1262	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
decreased circulating ghrelin level	MPO Gene-Phenotype Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85547
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38204
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053777
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3117-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
hsa-miR-214	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35346
CSTB_KO_GSE47516_677_mouse_mouse cerebellum P7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12415
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36343
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
CLINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78567
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8324
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13847
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955354
Endolymphatic hydrops	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35925
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49683
decreased circulating ghrelin level	MGI Mouse Phenotype Associations 2023	1.0	null
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44159
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.951215
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237513
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42963
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.237
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32877
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829237
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.72665
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06617
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24469
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
hsa-miR-9	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962784
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49998
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856386
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83236
UHO1	DepMap CRISPR Gene Dependency	1.0	3.05572
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07543
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40757
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77265
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10788
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
NT5C3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95497
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27592
NCIH209	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95955
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ITGB3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09375
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89544
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAZ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50998
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44068
DDX3Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62084
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02331
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10484
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.56169
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14924
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53679
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17616
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5213
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60138
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.45669
KCNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0809
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32017
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87988
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70208
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13802_KO_Mettl14_SRP286301	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.80062
ZNF891	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24608
PLCXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31221
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61415
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93305
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90523
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.5951
VPS26B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88578
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927661
increased circulating triglyceride level	MPO Gene-Phenotype Associations	1.0	null
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2081
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65089
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56336
hsa-miR-641	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02493
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1702
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60981
inactivates	GeneRIF Biological Term Annotations	1.0	null
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.00159
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836068
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased total body fat amount	MPO Gene-Phenotype Associations	1.0	null
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90755
membrane part	GO Cellular Component Annotations 2015	1.0	null
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17179
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67712
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65441
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92351
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75209
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SFT2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13274
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21913
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925968
abnormal circulating hormone level	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-93	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hsa-miR-98	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3924	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.985788
HDAC6	ENCODE Transcription Factor Targets	1.0	null
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57471
RASGRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91374
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92439
hsa-miR-185	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77759
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64045
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63516
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23012
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12474
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07967
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040572
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31427
USP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62768
epigenetic	GeneRIF Biological Term Annotations	1.0	null
CFAP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3485
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42194
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15192
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79176
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4555
ACAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33972
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91733
Perturb_13976_KO_H3f3a/H3f3b_ERP109384	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.6996
hsa-miR-4643	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33365
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940037
Medial mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05123
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	213.585
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.900083
EZH2	ENCODE Transcription Factor Targets	1.0	null
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29946
osteonecrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.874919
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61246
abnormal lipid level	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8390-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5502
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951428
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54013
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51943
Basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05096
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49035
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
CHLA57	DepMap CRISPR Gene Dependency	1.0	4.13021
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57955
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74847
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11105
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09206
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90157
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
HCC366	DepMap CRISPR Gene Dependency	1.0	2.84149
hsa-miR-3926	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8006
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6798
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61497
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1832
SLC44A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90578
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6677
LN464	DepMap CRISPR Gene Dependency	1.0	2.35376
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53785
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965384
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48977
NYNRIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44061
MAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38198
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972476
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936907
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0322
increased susceptibility to diet-induced obesity	MPO Gene-Phenotype Associations	1.0	null
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88726
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921919
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07339
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3569
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09157
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63966
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20748
abnormal anxiety-related response	MPO Gene-Phenotype Associations	1.0	null
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6635
TP53	ChEA Transcription Factor Targets	1.0	null
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56667
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0491
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867381
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
CPEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78045
REST_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4690-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3412
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61969
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45749
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840913
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1286
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.953591
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.077
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
SIN3B	ChEA Transcription Factor Targets	1.0	null
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.026
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920958
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42096
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
TCF3	ChEA Transcription Factor Targets	1.0	null
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11937
CUTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00712
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39418
PANC1	CCLE Cell Line Gene Expression Profiles	1.0	1.39963
ITLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.363
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.44443
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842083
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6777
STK33_knockdown_50_GSE15151	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.79155
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4174
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05898
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46968
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921658
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
hsa-miR-10b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-539	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10006
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89544
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.9188
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39338
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H-EMC-SS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_2_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPR137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9252
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	1.4467
H3K23ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59325
increased physiological sensitivity to xenobiotic	MGI Mouse Phenotype Associations 2023	1.0	null
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29229
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2445
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
MEX3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67507
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06047
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32743
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.00031
Anterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77391
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.88698
E2F6	ENCODE Transcription Factor Targets	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61744
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null