association	dataset	threshold value	standardized value
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3068
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15625
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
TNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48036
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.8959
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01792
sodium phenylbutyrate-502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31705
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23771
oliguria	MGI Mouse Phenotype Associations 2023	1.0	null
GSE110802_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35442
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.38567
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25865
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.487307
SYNCRIP_OE_GDS1886_83_human_THP-1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CBX8	ENCODE Transcription Factor Targets	1.0	null
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17365_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.5788
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A878-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14085
BRD-K24825509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27269
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904281
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041954
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01764
BRD-K35026224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67358
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.99336
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC3889573__F2	PFOCR Pathway Figure Associations 2023	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11372
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927207
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95634
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17682
abnormal nephron morphology	MPO Gene-Phenotype Associations	1.0	null
human bladder microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.779401
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
BRD-K92795658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02026
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pulmonary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09762
Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79734831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22346
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51117
signals	GeneRIF Biological Term Annotations	1.0	null
actomyosin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.204039
abnormal kidney physiology	MPO Gene-Phenotype Associations	1.0	null
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20742
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9326
BRD-K24263752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24779
BRD-K08899466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19652
BRD-K38190084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27624
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19021
ZNF581	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80177
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_12_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03878
BRD-K00557942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56047
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
phospholipase C-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7765-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
abnormal respiratory system morphology	MPO Gene-Phenotype Associations	1.0	null
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37973
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90358
BRD-K75857911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03684
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.99803
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25959
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837855
BRD-K67016489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03442
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50177754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14876
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NE 52-QQ57	DGIdb Drug Targets 2026	1.0	26.466
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
chloroxylenol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6483
lysophosphatidylcholine	GeneRIF Biological Term Annotations	1.0	null
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
endogenous	GeneRIF Biological Term Annotations	1.0	null
PMC6874977__F3	PFOCR Pathway Figure Associations 2023	1.0	null
PMC12630751-41540_2025_602_MOESM2_ESM.xlsx-Sustained_Angiogenesis-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00093
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.939956
Renal tubular acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.556
SNU387	DepMap CRISPR Gene Dependency	1.0	2.16514
regulation of cell adhesion	GO Biological Process Annotations 2025	1.0	null
microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216203
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35824
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_78_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
cyclic adenosine monophosphate-5108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.983752
Meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06652
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K89524688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14621
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53937
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35181
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61034
postulated	GeneRIF Biological Term Annotations	1.0	null
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67989
BRD-K89399989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16001
Perturb_15424_KD_PXN_SRP199381	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.59586
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061441
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.95433
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06585
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K04722226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61719
positive regulation of small GTPase mediated signal transduction	GO Biological Process Annotations 2025	1.0	null
BRD-K94090114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16193
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH647	CCLE Cell Line Gene CNV Profiles	1.0	2.23206
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043182
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.49303
SNU738	DepMap CRISPR Gene Dependency	1.0	5.72065
Osteophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01641
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44945
Krabbe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.61515
TMEM178A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05072
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0891
E2F1	ChEA Transcription Factor Targets	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70192
Adrenocortical carcinoma_ACC_TCGA-OR-A5JC-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11277
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71873
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054923
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06028
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18797
phenacemide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2362
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37265
dorsal tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06305
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parbendazole-4357	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.592
BRD-K83942575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26017
BRD-K64264263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58417
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22208
stress fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.26166
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29918
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501965
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11307
SNU620	DepMap CRISPR Gene Dependency	1.0	6.1605
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60499
vestibular nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869149
GSE128730_4_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PECAPJ49	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06066
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39602
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.290103
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42206
B16-F10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
TE4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4575
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65410345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17293
SNU886	CCLE Cell Line Gene CNV Profiles	1.0	1.35732
FOSL1	ENCODE Transcription Factor Targets	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94571
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
Meningoencephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40835
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01866
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31882
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
20421987-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
piperacetazine-6152	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-510	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41683
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.03653
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916771
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7170-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40199
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0386
zardaverine-7347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal renal/urinary system morphology	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39549
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23087
pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183286
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.62059
thioproperazine-2073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03779
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10157
PNPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68953
YD38	DepMap CRISPR Gene Dependency	1.0	4.11774
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98969488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34073
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15202679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61532
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51876
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05805
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34872
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
lateral group of nuclei, left, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22083
systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.241895
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05704
Xenopus A6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71542
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95119
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34507
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27816
WAOSEL	DepMap CRISPR Gene Dependency	1.0	2.99332
BRD-K12003101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16357
driving	GeneRIF Biological Term Annotations	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059886
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042014
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00819
identify	GeneRIF Biological Term Annotations	1.0	null
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
indometacin-503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184133,GSE184137_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.53844
JAK1_knockdown_160_GSE37012	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.52093
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.817128
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13444
BRD-K72821236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36252
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99732
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amiodarone-4657	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327896
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829094
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980533
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04231
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38637
COLO-829	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
hsa-miR-4769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LCAM1	DepMap CRISPR Gene Dependency	1.0	3.6789
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39082
methacholine chloride-6248	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055038
BRD-K41355409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29497
PMC6438015-13148_2019_651_MOESM7_ESM.xlsx-Sheet1-Table_S2_Genes_exhibiting_both_significantly_increased_promoter_methylation_and_significantly_lowered_expression_in_CRISPR_TET2-KO_cells_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GPR4 ANTAGONIST 3B	DGIdb Drug Targets 2026	1.0	26.466
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50203
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888225
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11902
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.22833
BRD-K77624847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02001
BRD-K49401787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42282
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35149
metastasis	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CD-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1339	CCLE Cell Line Gene Expression Profiles	1.0	1.77404
swiss-3t3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
BRD-K43969492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2448
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836632
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_33_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1081
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ligandindependent	GeneRIF Biological Term Annotations	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-0.956564
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15554
SYK_knockdown_189_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78856
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHF8	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28213
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
Perturb_4368_KO_Peg10_SRP167954	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.47797
STAT4-19710469-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25936
midodrine-7156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
internal hemorrhage	MPO Gene-Phenotype Associations	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.84394
PMC6855629-pone.0225186.s005.xlsx-Sheet1-DEGs_upregulated_in_the_low_MEIS1_content_thalamus_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93591
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45161
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69I-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.35207
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57032
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908631
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64067
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14806
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31806725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.701
protoninduced	GeneRIF Biological Term Annotations	1.0	null
effective	GeneRIF Biological Term Annotations	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29992
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.03197
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99208
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860185
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78262
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.84967
BRD-K18142082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28075
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45017
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48518
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7236
Kidney Chromophobe_KICH_TCGA-KN-8434-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.31131
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.73036
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09872
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24679
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
BRD-K89284683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00722
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Fibromyalgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05962
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
residue	GeneRIF Biological Term Annotations	1.0	null
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22397
inflammatory	GeneRIF Biological Term Annotations	1.0	null
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30673
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	0.945955
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09802
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894428
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4981
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32552
ligands	GeneRIF Biological Term Annotations	1.0	null
t30-blood-rna_male_2w	MoTrPAC Rat Endurance Exercise Training	1.0	2.09156
BRD-K13289658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11085
GTEX-XGQ4-0926-SM-4AT4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13477
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05909
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849563
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.62385
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76069
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03226
BRD-K28653463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24035
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72060858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08936
BRD-K33371292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06579
SNU878	CCLE Cell Line Gene CNV Profiles	1.0	1.58667
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2765
molecules	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44483161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61262
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45044
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
appendices_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.0985
NCIH2170	CCLE Cell Line Gene CNV Profiles	1.0	1.56665
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07121
hsa-miR-323-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
mantle zone of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06462
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.889758
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994081
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bronchial epithelial hyperplasia	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08965
BRD-K24523560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00994
hsa-miR-942	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06614
GTEX-QV31-1326-SM-2S1QE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947872
renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
BRD-K41513047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41809
BRD-A23955117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08224
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54673
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78586
BRD-K72661036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15668
SP1	ENCODE Transcription Factor Targets	1.0	null
GCT	CCLE Cell Line Gene Expression Profiles	1.0	1.64091
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24688
protonsensing	GeneRIF Biological Term Annotations	1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.991959
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03705
IST-MEL1	GDSC Cell Line Gene Expression Profiles	1.0	1.51871
BRD-K52148119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65123
Signaling by GPCR	Reactome Pathways 2024	1.0	null
NCIH2452	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75541
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92635
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46651
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05108
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.157172
RBBP5	ENCODE Transcription Factor Targets	1.0	null
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33183
collagen disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178126
19808871-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Serotonergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.419
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07617
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.24965
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70521
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43N-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37783
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870944
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.713
GTEX-WH7G-1126-SM-3NMBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4826
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20622
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826353
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03219
PMC4850258__F5	PFOCR Pathway Figure Associations 2023	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55024
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62517
BRD-K80332123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68535
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853415
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-581	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00112
adhesion	GeneRIF Biological Term Annotations	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059608
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4870-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
gpr4	GeneRIF Biological Term Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826014
BRD-K23674935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08268
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	0.940921
high-affinity iron permease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.307
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10587
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06262
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01192
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07778
H4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52136
hsa-miR-4666-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
hsa-miR-448	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17686226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43162
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61664
microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.205189
UACC257	BioGPS Cell Line Gene Expression Profiles	1.0	1.27101
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.488276
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27466
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45685
formation	GeneRIF Biological Term Annotations	1.0	null
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5238
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26385
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
mammary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129511
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931752
rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.203604
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827448
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81989
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39339
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01103
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27448
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34803
abnormal vascular smooth muscle morphology	MPO Gene-Phenotype Associations	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
Head And Neck Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834737
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91786
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90827
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35876
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
BRD-K02635441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1521
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.695763
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3284
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-GSX1_GSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64703
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32479
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945963
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849944
BRD-K12784613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24116
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01481
BRD-K45677957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05881
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5677_KO_Pcgf1/Pcgf6_SRP269225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.21955
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88239
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4086
CTCF	ENCODE Transcription Factor Targets	1.0	null
C4orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63872
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59608
t30-blood-rna_male_1w	MoTrPAC Rat Endurance Exercise Training	1.0	1.31434
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15203
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064268
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76888
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47007
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908631
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65334
BRD-K61973443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05949
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.89721
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38177
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.84609
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
EPOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96372
NCI-H1299	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08485
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04102
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.78289
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.43205
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1483
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04067194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4222
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7428
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856818
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11937
REST	ChEA Transcription Factor Targets	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059003
BRD-A05823365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.941
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02872
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
Malignant Head And Neck Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_45_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00647
responds	GeneRIF Biological Term Annotations	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2065
Perturb_9150_KD_WTAP_SRP307037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.83525
GTEX-XXEK-2426-SM-4BRUS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63262
skin hemorrhage	MPO Gene-Phenotype Associations	1.0	null
meclofenamic acid-2128	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78711
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370655
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942339
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49635
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061681
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6355
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10535
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892177
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	2.2311
hsa-miR-4264	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_72_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02777
Endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.605
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20256
Perturb_12711_KD_KMT2D_SRP062172	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.6284
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1KW-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975848
abnormal cardiovascular system morphology	MPO Gene-Phenotype Associations	1.0	null
EPHA7	MSigDB Cancer Gene Co-expression Modules	1.0	null
HO-8910PM	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77122
abnormal skin vasculature morphology	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-548k	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K05068331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46978
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13623
SP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10673
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98339
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48175
medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306083
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8449
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25449
hsa-miR-4450	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46913
NCIH226	CCLE Cell Line Gene Expression Profiles	1.0	1.47825
BRD-K06146578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21508
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89684
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
oxybutynin-3168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24195
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00304
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64544
apnea	MGI Mouse Phenotype Associations 2023	1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
hsa-miR-1228	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
RCOR1	ENCODE Transcription Factor Targets	1.0	null
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86097
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.84411
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
increased urine osmolality	MGI Mouse Phenotype Associations 2023	1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12455
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242983
PL4	DepMap CRISPR Gene Dependency	1.0	2.93802
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99349
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19402
ACC3	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.09135
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91413
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34579
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917661
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851555
required	GeneRIF Biological Term Annotations	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8905
MEIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92785
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47321
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.77235
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91573
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65516
Perturb_9880_KD_RUNX1_SRP368113	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.06527
PANC1	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06509
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.902942
metanephrine-1933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
camp	GeneRIF Biological Term Annotations	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_0_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69068
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11829
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296013
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.703007
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170054
BRD-A30547447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27255
CD248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
Autonomic nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24964
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75057
SOCS3_KO_GDS3149_297_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056945
mantle zone of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23598
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04854
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99792
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6986
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56942
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956705
Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40142
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28658
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6018-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
angiogenic	GeneRIF Biological Term Annotations	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32479
kidney hemorrhage	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_299_KD_TPRX1/TPRX2/TPRXL_SRP361145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.79385
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05703
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37579
FOSL1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.910305
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediated	GeneRIF Biological Term Annotations	1.0	null
Orphan GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
HIF1A_01_348	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58565
GRHL2-25758223-PLACENTA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K37356599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27232
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.07244
RMUGS	CCLE Cell Line Gene CNV Profiles	1.0	1.61467
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875195
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
ILF2_02_152	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98545272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00218
BRD-K63806140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33185
abnormal cardiovascular system physiology	MPO Gene-Phenotype Associations	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82628
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1681
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041371
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829715
BRD-K17175263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96255
BAY-11-7085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29765
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.832588
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82433
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962159
BRD-K02920459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0499
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
mainly	GeneRIF Biological Term Annotations	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46671
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87254
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11062
abnormal gas homeostasis	MPO Gene-Phenotype Associations	1.0	null
phospholipase C-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87332
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35602
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45044
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86155400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00604
Signal Transduction	Reactome Pathways 2024	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06312
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7447
melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078145
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20524
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
histidine	GeneRIF Biological Term Annotations	1.0	null
spironolactone-2064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A822-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1883
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.966726
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.62126
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065363
AGO1_02_162	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
BRD-K30682979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99619
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S2-HSF1_CanSig_Genes-HSF1-CanSig_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88155
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78782
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991093
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	GO Biological Process Annotations 2023	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35115
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.623079
SYK_druginhibition_154_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.65956
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889689
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV44-1825-SM-447CF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17632
cyanosis	MPO Gene-Phenotype Associations	1.0	null
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00563
BT12	DepMap CRISPR Gene Dependency	1.0	2.24026
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15665
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33881
Prostate adenocarcinoma_PRAD_TCGA-VN-A88K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.117
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896136
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5622
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978605
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065218
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39807
BRD-K67390061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01153
NCIH2087	CCLE Cell Line Gene CNV Profiles	-1.0	-2.36757
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.89422
ogr1	GeneRIF Biological Term Annotations	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12869
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51876
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915399
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20275
intermediate stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.223
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99978
SPI1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4646-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7213
hemorrhage	MPO Gene-Phenotype Associations	1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9580020-tx2c00131_si_003.xlsx-Fig_5A_data-HSF1_KOVAC_same_dataset_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82486
BRD-K90284572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.017
BRD-K03810133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08205
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3192
BRD-K39773004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22632
N1E-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02354
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.2458
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296372
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cho cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315498
GTEX-P4QS-0226-SM-3NB1U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880666
Kdm1a_KD_GDS5055_274_mouse_3T3-L1 preadipocytes - 24h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal respiration	MPO Gene-Phenotype Associations	1.0	null
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06805
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87733
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal lung epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
ONS76	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54536
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19541
GPCRs, Class A Rhodopsin-like(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943351
tonzonium bromide-4617	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896689
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320793
GH3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.00202
skin	HPA Tissue Protein Expression Profiles	-1.0	-1.02945
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13263
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85547
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881104
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065493
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eoc	GeneRIF Biological Term Annotations	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06614
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61593
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25844
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45897
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07943
PMC4989457-13073_2016_339_MOESM9_ESM.xls-MITF_D1_vs_D10-Gene_id_HUGO_ID_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19313
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95500312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20191
FRK	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K61886116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28885
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_21_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11154
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02908
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15444
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914889
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047876
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.790023
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14696
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.799375
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.24103
partial neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JAK2_mutant_40_GSE11003	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.67502
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840747
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00991
BRD-K76960042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05088
mammary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.125446
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841285
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3931
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6774-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96839003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55522
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22206
BRD-K96218803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05681
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12672
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32479
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.74059
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58996
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28204
inner CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828701
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypoglossal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
BRD-K41307363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01978
GCIY	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
BRD-K04712840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11315
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4815
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46015
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.943785
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09461
n1e-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463787
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47794327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64639
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCBP2_02_135	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.64386
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2174
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73748
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962159
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51146
BRD-K78869873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5234
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33334
fat_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.43685
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66089
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30429
Perturb_9834_KO_miR31_SRP354225	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.8529
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SIRT1_KO_GDS3666_295_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68656
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1226-SM-3TW8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92082
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A50E-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
bronchial epithelial hyperplasia	MGI Mouse Phenotype Associations 2023	1.0	null
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24002
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73473
Perturb_13254_KD_Ncaph2_SRP073037	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.41737
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04197
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17975
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832083
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09762
SKMEL24	DepMap CRISPR Gene Dependency	1.0	2.30445
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29426
GSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50514
BRD-K73176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09053
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394953
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20673
icSARS CoV_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.13971
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00373
BRD-K47348275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2701
BRD-K97472167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08005
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.245
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
relative	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17772
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74827
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931498
BRD-K12175788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2789
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970628
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02439
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.80426
Umbilical vein endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02527
Cryptococcal meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89476396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19121
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04465
JHUEM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77987
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62369921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3474
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
propranolol-3059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77601667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06508
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4865
RAD21	ChEA Transcription Factor Targets	1.0	null
GTEX-XUW1-2326-SM-4BOO5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25615
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.598
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37329
spiramycin-2558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4659b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM22_02_168	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.85798
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925409
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
TIMM17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0672
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42339
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40835
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
asiaticoside-3504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17284527-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dejerine-Sottas Disease (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1491
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.719113
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99354
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-FERNANDEZ_BOUND_BY_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0226-SM-48TBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01789
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8262
BRD-K28937085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12508
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2024	1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5356
resulting	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05992
mammary epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138608
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60546
BRD-K05041614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28024
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35882
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11731
GTEX-TKQ1-0226-SM-33HB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929093
TE441T	CCLE Cell Line Gene Expression Profiles	1.0	1.91954
BRD-K39247583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17256
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5370-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09006
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.354
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
HEL	DepMap CRISPR Gene Dependency	1.0	2.40959
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58703
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	1.42881
promonocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476201
BRD-K73706189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32685
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04568
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31664
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.25145
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2027
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	1.71139
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31463
MM77	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13265
TTC549	DepMap CRISPR Gene Dependency	1.0	4.20121
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36018
BRD-K59049340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5035
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1128
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3421
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32773
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
SW-1353 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
abnormal respiratory epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
Helaohio	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
BRD-K98841583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75225
Perturb_8489_KD_ETS1_SRP113518	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.0305
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91413
hsa-miR-875-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21614
methocarbamol-2111	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64743
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37561
PMC12035534-gfae237_supplemental_file.pdf-64-RUNX1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02232
taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.369373
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_69_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07984
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.581126
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81406
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87661
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38587
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13555
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51394
thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278251
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.4092
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061039
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29856
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VEGF_A_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
BRD-A71880598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43215
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07372
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07435
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946519
8305C	CCLE Cell Line Gene Expression Profiles	1.0	1.54828
BRD-K94516254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06524
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24185
CDK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79561
PMC10350897-j_biol-2022-0528-S1.pdf-68-GPBP1L1_GPBP1L1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66939
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77003
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09872
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850569
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37442
BRD-K66590796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06706
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80525
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.183248
Learning Disorders	CTD Gene-Disease Associations	1.0	1.08231
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16096
PMC5725737-IJC-142-297-s013.xlsx-DTC_mna_vs_TUM_mna-DTC_MYCN-high_vs_TU_MYCN-high_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7397-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35387
positive regulation of Rho protein signal transduction	GO Biological Process Annotations 2023	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54257
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78943
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846106
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11557
BRD-K51278788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41713
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC10949864__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Congenital disorder of glycosylation Iy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67954
BRD-K31575995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03196
PMC11760944-41598_2025_86694_MOESM1_ESM.pdf-112-FOXJ1_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30706
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13433
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28452
hsa-miR-3199	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864439
BRD-K71437774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39522
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83276
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5565-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47574
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF_01_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58514
YWHAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80493
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.77581
GTEX-PWCY-1926-SM-3NB25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95333
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12440228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13727
BRD-K08205503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2525
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.05608
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27782
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.842365
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19578
RI1	CCLE Cell Line Gene CNV Profiles	1.0	1.61982
BRD-K99339232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24497
ATDC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
BRD-K95735171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43021
KP2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66244
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.885714
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83898111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28236
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.858
MAN2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49433
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06325
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64241
not applicable_Hypothermia_GSE54229_131_mouse_Embryonic fibroblas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55554
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ethosuximide-1433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WH-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60589
felodipine-337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T84	DepMap CRISPR Gene Dependency	1.0	3.00158
BRD-K59765110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32496
GTEX-S4P3-1526-SM-3K2AV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827667
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310059
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932935
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55828
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PK-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54088
H3K27me3_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91413
JJN3	DepMap CRISPR Gene Dependency	1.0	4.8668
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20637
GTEX-T5JC-0526-SM-32PM7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924254
BRD-K13401825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05766
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02527
GTEX-S32W-2026-SM-4AD6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49626
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96704
hsa-miR-4699-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.311145
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01168
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RI1	DepMap CRISPR Gene Dependency	1.0	2.15914
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-371b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18126
ursolic acid-2067	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62819
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.989085
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938559
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13555
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.24478
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5858
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K98367403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03112
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33271
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22316
PMC4090731-bjc2014262x1.xls-Sheet1-CaSig-HSF1_Positive_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
CBX2	ENCODE Transcription Factor Targets	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1417
melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249653
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16164
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49546
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A6BG-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98339
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077136
Brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
abnormal renal corpuscle morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
tongue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277197
Dermal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.07026
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63543
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7265
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99436
GTEX-Q2AI-1426-SM-2S1P5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955637
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041373
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061622
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54877231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24642
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72677
BRD-K01095342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40008
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.81053
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3588
response to acidic pH	GO Biological Process Annotations 2023	1.0	null
Microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acetylsalicylsalicylic acid-2061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054258
BRD-A98203122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69595
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920944
abnormal muscle morphology	MPO Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58432
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.22771
BRD-K54814515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58964
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01387
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02948
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
glomerulus hemorrhage	MPO Gene-Phenotype Associations	1.0	null
BRD-K54463500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92492
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27438
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66507
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884083
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19264
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11412
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21037
TYK-nu	GDSC Cell Line Gene Expression Profiles	1.0	2.81293
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078091
TRIFLUPERIDOL-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35037
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.86081
BRD-K87461415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6773
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
PC-3	GDSC Cell Line Gene Expression Profiles	1.0	2.30295
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.156
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84944
SUM229PE	DepMap CRISPR Gene Dependency	1.0	2.05351
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26245
decreased pulmonary ventilation	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K08438266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67933
monocyte	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075679
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46759
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936661
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.42881
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2363
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0314
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal breathing pattern	MPO Gene-Phenotype Associations	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.752
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54144
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32368
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40693
BRD-K21036759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15558
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18636
Renal medulla cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721988
tumors	GeneRIF Biological Term Annotations	1.0	null
BRD-K05846874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07258
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.862832
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5569-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16941_KO_Mkrn1_SRP149173	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.99514
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44098
lateral part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05452
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82089
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77583
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32107
hsa-miR-1267	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K06313694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10066
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43035
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	2.39861
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96946
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.42881
Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83386
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of inflammatory response	GO Biological Process Annotations 2023	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0186
SALL4-18804426-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55973
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39633
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
BRD-A06327019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07567
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.54639
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17629
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39967
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09186
HCC1359	CCLE Cell Line Gene Expression Profiles	1.0	1.77652
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.443
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.02519
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6868
phenylalanine	GeneRIF Biological Term Annotations	1.0	null
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81204
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7588
neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
gentamicin-2082	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.02671
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34356
BRD-K66868536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18942
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41509
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37386
BRD-K99517495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01708
GTEX-OIZH-0226-SM-2YUMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0405
postnatal lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
placenta_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.03858
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6919
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08389
DANG	CCLE Cell Line Gene Expression Profiles	1.0	1.45993
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90358
BRD-K52303942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12146
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2697
Perturb_12788_KO_Gba_SRP385574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.88214
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-3.98805
NCI-H1792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23901
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24053
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55945
Perturb_9138_KD_SNAI1_SRP133893	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.7609
PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-DANG_BOUND_BY_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10374
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14279
HDLM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48471
Syndromic X-linked intellectual disability Cabezas type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15085
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.12746
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2366
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-11A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1794
Perturb_11380_KD_GATA2_SRP178865	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.09042
BRD-K02420839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0529
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11782
RAB39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86868
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02814
BRD-K91060460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65833
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55044
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60331
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_39_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73056
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.88191
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07591
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877137
GSE137818_5_v_0_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853163
GTEX-XV7Q-2326-SM-4BRVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22833
brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099933
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915839
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65402
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
BRD-K88964321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60596
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060068
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I9-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.362422
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11562
OBSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40225
u-937 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476201
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
G alpha (q) signalling events	Reactome Pathways 2014	1.0	null
gscampepac	GeneRIF Biological Term Annotations	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.88859
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946754
BRD-K06500446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23976
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51001
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hemoperitoneum	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23921
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.881626
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28435
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36822
lung hemorrhage	MGI Mouse Phenotype Associations 2023	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040473
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61635
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15206
actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.256925
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.935965
GSE156978_1_v_0_dnmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LbetaT2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27442
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34926
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01876
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37162
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AKAP8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15527
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE77108_6_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.86059
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1813
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16105
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLAGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45673
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085182
hsa-miR-4284	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06902
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ascites	DisGeNET Gene-Phenotype Associations	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
CYB5D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96507
Kdm1a_KD_GDS5055_275_mouse_3T3-L1 preadipocytes - 48h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08799
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04069
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56385
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-1226-SM-4BRUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27111
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24978
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03915
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80991
BRD-K22537050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04396
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09664
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.716241
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994546
regulation of Rho protein signal transduction	GO Biological Process Annotations 2023	1.0	null
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13813
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865283
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16407
Sarcoma_SARC_TCGA-DX-A3M1-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F4_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16789950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24405
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55325
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.962892
intermediate stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25584
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22359
abnormal angiogenesis	MPO Gene-Phenotype Associations	1.0	null
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53016
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22665
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
partial postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02956
hsa-miR-1233	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Secondary Malignant Neoplasm Of Lymph Node	DisGeNET Gene-Disease Associations	1.0	null
BRD-K08679933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26916
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_NANOG_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
constitutively	GeneRIF Biological Term Annotations	1.0	null
Rectal Prolapse	DisGeNET Gene-Disease Associations	1.0	null
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88778
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927218
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54128
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922395
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.801876
BRD-K90693562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94932
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4224
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27171
posterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09822
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09872
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81644801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22476
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63323
ZNF777	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3612
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040573
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:E12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03367
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940189
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01667
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09028
BRD-K92913067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16662
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31067
ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.230409
isoniazid-2083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10248509-Data_Sheet_6.CSV--GSE66724_DE-Genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
CH157MN	CCLE Cell Line Gene Expression Profiles	1.0	1.68387
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6484-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5901
ventral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12827
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70561
t30-blood-rna_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	7.57369
BRD-A94046266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02773
NCIH716	CCLE Cell Line Gene Expression Profiles	1.0	1.4847
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.38541
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.991512
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889698
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06037
Leukodystrophy disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080824
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE114894_1_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056443
abnormal renal glomerulus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Spinal trigeminal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9276
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935571
brain endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225395
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.487711
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_66_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22637
BRD-A32018906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97359
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00254
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.16559
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44706
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K43922968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16997
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72515
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08344
BRD-K41451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13054
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01866
kidney hemorrhage	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lpc	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076061
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24977
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80918
BRD-K82504878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0408
hsa-miR-3126-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16677
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.252
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_54_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal vascular development	MPO Gene-Phenotype Associations	1.0	null
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07598
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1536
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Slime layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
BRD-K88527653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45806
collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34334
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64395
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04917
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89369
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3054
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056408
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37419
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14252
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL4	ChEA Transcription Factor Targets	1.0	null
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K58827489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91709
BRD-K02093145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12468
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14844
acidosis	MGI Mouse Phenotype Associations 2023	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049637
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02733
BRD-K76885311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84107
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.93896
BRD-K75710031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60391
MYSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15671
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69964
Weibel-Palade body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20972
Fatty Liver	CTD Gene-Disease Associations	1.0	1.052
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37986
abnormal bronchus epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853823
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910111
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92915
first (dorsal) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23747
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.94753
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal respiratory function	MPO Gene-Phenotype Associations	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44306
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03025
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49818
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03211
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20104
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42956
BRD-K64859133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16208
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98147
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.125104
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4683	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54029
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79169
abnormal blood circulation	MPO Gene-Phenotype Associations	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
dorsal part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0643
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0653
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.855424
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
endothelial	GeneRIF Biological Term Annotations	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
epithelial	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03351377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51801
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11115
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843206
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2665-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76124
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59047
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32192
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
FOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47277
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28141
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-1426-SM-4BOPW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986685
STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326067
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15079
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
BRD-K22137463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57086
ARC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54078
BRD-K76763044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06836
POU5F1	ChEA Transcription Factor Targets	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4591
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51502
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37589
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
human lung microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.674543
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914429
extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.24894
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3262
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59687
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	2.60394
furazolidone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1847
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56605
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
KIF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98209
BRD-K38345640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33232
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.991616
Intralaminar nuclei of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30886
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25883
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874153
BRD-K96560179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10537
PANC0327	DepMap CRISPR Gene Dependency	1.0	9.24417
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.44968
abnormal smooth muscle morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61833
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.1237
GSE192689_0_v_3_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.28676
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10692
abnormal renal/urinary system physiology	MPO Gene-Phenotype Associations	1.0	null
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02063
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16043
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-643	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2663
Lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904317
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18499
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04497
hsa-miR-511	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987958
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308251
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2558
TAF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3BZ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.90982
GSE134700_0_v_4_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFO-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58324
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938843
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06712
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91851
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.852
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10287_Mut_Lmna_SRP309326	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.37547
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31239
OCIM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73876
molecular_function	GO Molecular Function Annotations 2015	1.0	null
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67354
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56011
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870699
BRD-K81647247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33368
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25186
lung hemorrhage	MPO Gene-Phenotype Associations	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.2565
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66503
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67367
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8807
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.05
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00866
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.404804
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64235
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97133
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900827
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75062
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6347
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79487
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969147
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5121-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dermatofibrosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904774
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.67495
PMC12648952-12915_2025_2452_MOESM4_ESM.xlsx-S4c-Pseudobulk_AP2_vs_B57-Unnamed_11_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77486
GATA2	ENCODE Transcription Factor Targets	1.0	null
BRD-K59272984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09536
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76107
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78504
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969545
Prestwick-860-5679	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835964
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35555
f1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982124
Lymphadenopathy	DisGeNET Gene-Phenotype Associations	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
FRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5715
CP-690334-01-3823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.945405
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73985
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18387
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53771043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79698
AG-013608-6440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
increased urine creatinine level	MGI Mouse Phenotype Associations 2023	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996509
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1666	GDSC Cell Line Gene Expression Profiles	-1.0	-1.87804
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14068
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29177
BRD-K10269761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08624
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6288
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	0.958339
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35732
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22245
metampicillin-2123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal tumor vascularization	MGI Mouse Phenotype Associations 2023	1.0	null
amoxapine-1931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01866
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BTS	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98093
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6025
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042782
hsa-miR-3679-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
myotonic dystrophy type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.473361
pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42993
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.787
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047967
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07668
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05208
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08349
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
Initial collecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8756
petechiae	MPO Gene-Phenotype Associations	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22129
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Perturb_12780_KO_C5ar1_SRP097094	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.70949
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.2332
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9663
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.67763
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
haloperidol-418	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.36432
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.487711
malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.232142
SALL4-18804426-XEN-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918457
HMX1_Deficiency_GDS4810_324_mouse_Retinas of C57BL/6J	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116666
NEU3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2469
LNCAPCLONEFGC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97183
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
brain microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.451813
BRD-K00974016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07641
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
BRD-K50133846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17426
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49903196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99385
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.56371
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15795
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscle-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	1.29307
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37973
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02161
JUND	ENCODE Transcription Factor Targets	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15621
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Ferroxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27962
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55932
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958606
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44203
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860141
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92291
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12752_KO_Per1/Per2_SRP315570	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65315
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02815
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20423
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07281
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84348716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.17578
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17519
BRD-K96149826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04346
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0786
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50754
b16-f10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.601283
TGW	GDSC Cell Line Gene Expression Profiles	1.0	1.42632
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
NANOG-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842097
lysophosphatidic	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850796
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964014
extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.2708
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal respiratory conducting tube morphology	MPO Gene-Phenotype Associations	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2803
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25281
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17222
BRD-A98888138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.28887
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52999
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83122
PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42325
abnormal bronchus morphology	MPO Gene-Phenotype Associations	1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28316
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17577
Perturb_4205_KO_Top1_SRP072888	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.90784
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K25638876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25486
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
BRD-K83481256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12411
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.983584
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smoothmuscle_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.877393
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
BRD-K25877713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1307
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911059
ethaverine-3037	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34862
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57517066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76072
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.35563
hsa-miR-587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13757
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03819
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.428678
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.418
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18227
BRD-K46412655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20324
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.52318
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201217_2_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.00311
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WI4N-1426-SM-3LK7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961537
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887776
HS766T	CCLE Cell Line Gene Expression Profiles	1.0	1.60882
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15266
MYC	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0621
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT1376	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53877
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03816
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47287
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15663
BRD-A15330900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55976
breast	GTEx Tissue Gene Expression Profiles	1.0	0.937669
Cerebrovascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02946
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33198
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.47078
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-1126-SM-4AD6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05341
GTEX-S33H-0626-SM-2XCBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15215
HDAC2	ENCODE Transcription Factor Targets	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93483
dermal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.359664
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.8601
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Prolactin producing pituitary tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.854367
proinflammatory	GeneRIF Biological Term Annotations	1.0	null
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.168
GPR27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66196
BRD-K13681581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1924
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
Glomus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.551
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932644
beta-escin-3807	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976157
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00932
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27769
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	4.50033
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
positive regulation of response to external stimulus	GO Biological Process Annotations 2023	1.0	null
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16586
hsa-miR-661	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08502
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07566
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57621
BRD-K40361885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22112
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	1.0	1.49202
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02636
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	2.64477
hsa-miR-153	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00806
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.934217
Superoxide dismutase copper chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.279
SNB19	CCLE Cell Line Gene CNV Profiles	1.0	1.91498
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507064
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_24_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11633
acidosisgpr4	GeneRIF Biological Term Annotations	1.0	null
Dosage-Sensitive Sex Reversal	DisGeNET Gene-Disease Associations	1.0	null
GSE211128_7_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11876
GSK3B_knockdown_204_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.46705
BRD-K45631723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60118
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal angiogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22215
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841499
BRD-K54751293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02476
Rectal prolapse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63707
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1206
GSE134375_6_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K31462164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25184
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982711
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.50048
HOP62	CCLE Cell Line Gene CNV Profiles	1.0	3.19814
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02817
12115547-Table4	GeneSigDB Published Gene Signatures	1.0	null
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51682
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4-P-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75846
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	1.38786
CHD7	ENCODE Transcription Factor Targets	1.0	null
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29259
Organum vasculosum laminae terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17637
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48177
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41066
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951785
BRD-K42663584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58089
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A8S6-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485545
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Signaling by GPCR	Reactome Pathways 2014	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82019575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66525
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.907053
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.248
Uterus-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.00643166
NCI-H1299	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57864
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06146
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNMC	DepMap CRISPR Gene Dependency	1.0	4.08456
BRD-K92431275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10214
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.71193
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.656
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.604
SOCS3_KO_GDS3149_8_mouse_multiple cell types	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3ER-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3154	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
response to acidic pH	GO Biological Process Annotations 2025	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905424
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.828195
HSSCH2	DepMap CRISPR Gene Dependency	1.0	2.54421
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8563
breast epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118212
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCPAP	CCLE Cell Line Gene Expression Profiles	1.0	1.36492
BRD-K19817946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94942
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nterminal	GeneRIF Biological Term Annotations	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4405
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.272649
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78504
triprolidine-7248	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PIGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77893
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06043
Carbohydrate metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
rostral group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65626
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-35650195-DSRCT-HUMAN-MESENCHYMAL-SARCOMA	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45757
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7068
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84748
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleus of the stria medullaris (prethalamic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06523
Sporangiospore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
BRD-K26591929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04157
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.25404
Perturb_5136_KD_Dax1_SRP311833	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.47706
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
BRD-K03251393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74835
biological_process	GO Biological Process Annotations 2015	1.0	null
aminophenazone-2060	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987107
POLR2A	ENCODE Transcription Factor Targets	1.0	null
mechanisms	GeneRIF Biological Term Annotations	1.0	null
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65949
Skin-muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.309543
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
prosomere 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00714
BRD-K74779337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43351
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.952046
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Globoid cell leukodystrophy disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04157
PMC6874977__F3	PFOCR Pathway Figure Associations 2024	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08883
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69277
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19576
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23612
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TE-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883487
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Buccal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90969
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58316
Sarcoma_SARC_TCGA-DX-A8BV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83589
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
hsa-miR-4720-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K10696228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47534
BRD-K04992384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44562
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	8.69564
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.70974
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	2.70785
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04895
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095471
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051875
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9146
NPIPB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81265
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6197
BRD-K49040541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50405
WEHI-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05118861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42487
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.47374
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60783
BRD-K79932545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57482
BRD-K87399364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90749
carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14517
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.123
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05905
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01895
BRD-K02759046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01767
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03025
PMC6718408-41467_2019_11884_MOESM6_ESM.xlsx-TAD_genes_ST-EPN-RELA-Unnamed_4_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12267335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79334
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.583941
RAB5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14585
preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09216
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843152
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE206870,GSE206872_4_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399913
mp88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
AM-095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58128
IZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952971
HNRNPK_02_136	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36773
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1283	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34663
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.72487
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal respiratory system physiology	MPO Gene-Phenotype Associations	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
mebeverine-6795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	4.6864
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4469	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Human brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.42881
Pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19977
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53738
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36803
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7695
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Aortic body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.589
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47112
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07779
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K02073410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3232
tiotropium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04228
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.61515
r8 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33909
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215992
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01735
19861896-Table2	GeneSigDB Published Gene Signatures	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4170-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A38359809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39179
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K29547381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11563
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.9247
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21743
IRF1	ENCODE Transcription Factor Targets	1.0	null
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48017
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4073
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.04647
abnormal glomerular mesangium morphology	MPO Gene-Phenotype Associations	1.0	null
PMC3109512__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K50700697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22396
BRD-K19142902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13461
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30878
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896689
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.235964
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.17673
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1694
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10175
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93347
Brain Lower Grade Glioma_LGG_TCGA-DU-6401-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	3.29331
SUZ12	ENCODE Transcription Factor Targets	1.0	null
SAOS2	DepMap CRISPR Gene Dependency	1.0	2.25669
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LY-294002-501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LY-294002-318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hmc1	HPA Cell Line Gene Expression Profiles	1.0	1.19278
triggered	GeneRIF Biological Term Annotations	1.0	null
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53036
Colitis	DisGeNET Gene-Disease Associations	1.0	null
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00012
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51989
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35744
BRD-A89947015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07226
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
C33A	DepMap CRISPR Gene Dependency	1.0	7.50342
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2938
RHOD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78096
BRD-K41620124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91824
abnormal mesangial cell morphology	MPO Gene-Phenotype Associations	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972766
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
Carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052122
Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09782
BRD-K14041149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66295
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40898
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26283
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A15086915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6085
PMC7204122-4623107.f1.docx-6-GABPA_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.922749
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.30053
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47617
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
BRD-K07982814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5187
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22463
Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46714
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81516
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-STAT3_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
G protein-coupled receptor activity	GO Molecular Function Annotations 2023	1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12169
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830128
overexpression	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4279	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041796
KYSE-520	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45782
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4683
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0686
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38704
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4697456__F1	PFOCR Pathway Figure Associations 2023	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6274
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7069-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5316868__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25521
mesangial cell hypoplasia	MPO Gene-Phenotype Associations	1.0	null
ABHD16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69046
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37348
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0596
shifted	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28009
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34087
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897497
APP_KO_GDS4414_370_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Sarcoma_SARC_TCGA-DX-A6YU-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04365
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.97964
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34338
BRD-K47783463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39912
hydroxytoluic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00723
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16738
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35411
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.42881
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828455
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.58733
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_36_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77837
close	GeneRIF Biological Term Annotations	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.1628
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_48_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9043
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20941
side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.142276
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16305
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03408
BACH1	ChEA Transcription Factor Targets	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.499
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18776
HEYA8	CCLE Cell Line Gene Expression Profiles	1.0	2.21669
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902369
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58951
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10377
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852899
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070361
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28403
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K39348592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14292
AGS	CCLE Cell Line Gene CNV Profiles	1.0	1.48131
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64626
positive regulation of Rho protein signal transduction	GO Biological Process Annotations 2025	1.0	null
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54056
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83881
ec50	GeneRIF Biological Term Annotations	1.0	null
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
MALME3M	DepMap CRISPR Gene Dependency	1.0	8.90071
RKN	CCLE Cell Line Gene Expression Profiles	1.0	2.23232
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
Lung adenocarcinoma_LUAD_TCGA-44-2668-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nephrolithiasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
BRD-A78042852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25236
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17926
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17561
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.930739
GSE206870,GSE206872_4_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14887
abnormal kidney morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30773
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894654
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29069
Sarcoma_SARC_TCGA-3B-A9HL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K09146396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31977
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90935
GTEX-O5YT-0526-SM-32PK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04999
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K42995703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27769
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850569
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06805
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
CGR-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18391
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55295
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49927
KRAS.300_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
A-CA-04-2009(H1N1)_Day1_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.07273
regulation of Rho protein signal transduction	GO Biological Process Annotations 2025	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43983
EPM2AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19005
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858387
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11224
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38787
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14656
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50909
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32751
Integrator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
flufenamic acid-316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56063
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55928
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
human brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.800626
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258243
Giant Cell Fibroblastoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71854
BRD-K30699866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43851
BRD-K48875630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65795
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1855
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4212_KO_Mir140_SRP245562	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.61954
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59133
P2URK562	DepMap CRISPR Gene Dependency	1.0	4.44665
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
concentration	GeneRIF Biological Term Annotations	1.0	null
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal pulmonary circulation	MPO Gene-Phenotype Associations	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99087
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09184
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09762
NCIH2141	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92102
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
el2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
PMC9580020-tx2c00131_si_004.xlsx-Fig_5B_data-TABLE_S3_CORE_GENE_TARGETS_HSF1_KOVACS_ET_AL_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45959
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98701
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915839
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2407
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.943582
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965665
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08221
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A85216385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43445
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9167
Perturb_14868_KO_PU.1_SRP166067	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.46138
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56356
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06158
Acute Colitis	DisGeNET Gene-Disease Associations	1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37617
BRD-K80848948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82899
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35661
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.931248
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949963
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.88525
decreased urine calcium level	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K45498945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06705
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1933
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.8201
estradiol_homo sapiens_gpl14550_gse35034	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.119996
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04013
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53917
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.990479
angiogenesis	GeneRIF Biological Term Annotations	1.0	null
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11243
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZF-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310059
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93935
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986558
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47817
cloperastine-3710	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32479
Pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_15_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98841
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921267
HOP62	DepMap CRISPR Gene Dependency	1.0	2.81343
Trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
BRD-K69790201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25851
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04332
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22316
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7349
PMC4960540-srep30217-s5.xls-VD_metabolism-V_VDR_Q3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
SmoothMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.22545
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07879
BRD-K67592986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54612
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3657	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056623
BRD-K07396820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00857
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965469
Globoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
Tumor Angiogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59426
Fungal meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
renal tubular acidosis	MGI Mouse Phenotype Associations 2023	1.0	null
Thalamus, polymodal association cortex related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08691
BRD-K41006887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27383
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501965
BRD-K64753899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07165
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09872
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16265
molluscum contagiosum	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.01849
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843007
BRD-A63704386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14839
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory distress	MGI Mouse Phenotype Associations 2023	1.0	null
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02024
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21124
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_60_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01064
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81692
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
UPMD1	DepMap CRISPR Gene Dependency	1.0	2.59941
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53027
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37305
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938859
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19005
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23401
Osteosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12253
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970819
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
Aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_18_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
IMCD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943892
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15413
postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38029
VPS4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39018
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99011
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66425
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4758-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02965
GTEX-S4UY-0226-SM-3K2AP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997655
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
activated	GeneRIF Biological Term Annotations	1.0	null
GTEX-XGQ4-1026-SM-4AT4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01957
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.690042
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dipyrocetyl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70485
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.14942
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14719
G protein-coupled receptor heterodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03411
GPCR ligand binding	Reactome Pathways 2014	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923942
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1252
Supratrigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11708
TYKNU	CCLE Cell Line Gene Expression Profiles	1.0	3.40789
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91459
Prostate adenocarcinoma_PRAD_TCGA-CH-5754-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93726930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13216
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46872
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05391
positive regulation of response to external stimulus	GO Biological Process Annotations 2025	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962442
Adrenocortical carcinoma_ACC_TCGA-OR-A5J9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06105
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.113
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.977335
Myotonia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K74641261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29686
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969265
KDM1A_KD_GDS5055_367_mouse_adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04917
ZNF534	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77624
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
hsa-miR-4792	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
BRD-K64970964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06095
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP1R14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78767
abnormal vascular smooth muscle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.459373
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01106
Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065809
inner medullary collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.717061
hsa-miR-630	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.35964
inhibit	GeneRIF Biological Term Annotations	1.0	null
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63941
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07925
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21554
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.928
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069151
hypercapnia	MGI Mouse Phenotype Associations 2023	1.0	null
GSE211128_2_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07020302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0136
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12592
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Wnt signalosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.927
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72143
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07412
cefixime-4390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DOC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81097
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66798
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38677
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115409
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30219
Perturb_17320_KO_miR106b~25_ERP121195	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.8329
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20093
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331194
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916115
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.15776
elementbinding	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-483-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48518
Perturb_17362_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.661
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3357
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A81615860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41358
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01237
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824716
PRPF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49453
cyclic	GeneRIF Biological Term Annotations	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_11915_KO_Rankl_SRP190820	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.99817
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07106
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSF1_KD_GDS1733_757_human_HeLa cells - 4 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88301
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC3889573__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071238
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.2045
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
LY-294002-6175	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04784
BRD-K04741797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95537
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09782
GTEX-S32W-0326-SM-2XCBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38307
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54J-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFG_02_189	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61667
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
erk12	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48135
BRD-K24512597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31797
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964626
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32323
G alpha (q) signalling events	Reactome Pathways 2024	1.0	null
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC3122626__F8	PFOCR Pathway Figure Associations 2023	1.0	null
Disease	Reactome Pathways 2014	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.995161
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3143
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.42224
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03298
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00335
BRD-K34741587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29553
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Left colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
C6orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27733
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32516
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.02176
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06501
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09721398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09847
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19718
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.076
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053201
GSK3A_KD_GDS4305_182_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormal oxygen level	MPO Gene-Phenotype Associations	1.0	null
GSE240468_3_v_6_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21171
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52314
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_9_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69468381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10561
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42667
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19959
TGBC1TKB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58425
Thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00259
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43939
GPCR ligand binding	Reactome Pathways 2024	1.0	null
prethalamic eminence	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06462
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16551
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80801
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069675
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11428309-12920_2024_2011_MOESM1_ESM.pdf-2-TSC22D1_TSC22D1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.46737
alar plate of p2 (alar thalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06715
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11372
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
STAT4	ChEA Transcription Factor Targets	1.0	null
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H19_DEPLETION_GDS4787_92_mouse_C2C12 myoblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K54554531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86311
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3303
NUMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33373
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44754
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03547
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044788
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03303
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60589
LS123	CCLE Cell Line Gene CNV Profiles	1.0	1.51032
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38572
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18893
PMC9174882-EMMM-14-e15816-s002.xlsx-ThCell_GeneSigs-GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_UP_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25501
GTEX-UPK5-1826-SM-3GAEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09181
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03209
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86132
valproic acid-1209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39094
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.362422
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962158
BRD-K27120020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11134
BRD-K96567801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69314
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38784
biological regulation	GO Biological Process Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883237
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932318
BRD-K28057105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18433
BRD-K37698302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46814
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
intermediate tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08628
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K26968526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13747
PRDM14	ChEA Transcription Factor Targets	1.0	null
GTEX-WHPG-0626-SM-3NMBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36838
GSE209928_0_v_1_kmt2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4654	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cryptococcosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.782
Lung adenocarcinoma_LUAD_TCGA-44-6145-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19777
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.13597
scopolamine-4803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4141
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00233
BRD-K35066174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68876
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRSF4_02_12	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22527
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10451
PMC7529806-41467_2020_18638_MOESM7_ESM.xlsx-Supplementary_Data_4-Supplementary_Data_4_TG_of_EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03632
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.302
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
decreased mesangial cell number	MGI Mouse Phenotype Associations 2023	1.0	null
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.00625
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19351
lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.184023
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896689
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20468
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.892685
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_57_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57631
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r1 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25433
primaquine-4263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
changes	GeneRIF Biological Term Annotations	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.583621
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33479
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_27_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864931
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7081
BRD-K13754152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19524
ZNF132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99372
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80087
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_51_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.88837
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87812
MDA-B02 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
BRD-K10705624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86029
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06611
ovarian	GeneRIF Biological Term Annotations	1.0	null
Perturb_17360_OE_HDAC4_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.699
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
hemorrhage	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11708
SNU410	DepMap CRISPR Gene Dependency	1.0	3.14895
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47552
PMC6423903__F1	PFOCR Pathway Figure Associations 2023	1.0	null
NANOG-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52833
BRD-K47650707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04714
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61813
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XXEK-1426-SM-4BRW1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35542
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.931248
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852272
Squamous Cell Carcinoma Of The Head And Neck	DisGeNET Gene-Disease Associations	1.0	null
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853844
NCI-H250	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
BRD-K98940411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84899
GSE155031_5_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00175
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947108
Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52136059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42326
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-0.931248
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50877
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.2405
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948771
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.59011
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6212
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65516
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.565
NB7	GDSC Cell Line Gene Expression Profiles	-1.0	-1.87704
Sarcoma_SARC_TCGA-K1-A6RU-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84145110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3767
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GT1-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
BRD-K05471809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20905
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24711
ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.23353
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964777
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3325
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.3228
CRCGN015_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.015
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18234
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15085
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4767
BRD-K18296708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31292
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-376-SCMH1_SCMH1	Rummagene Transcription Factor Associations 2026	1.0	null
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
membrane part	GO Cellular Component Annotations 2015	1.0	null
elicits	GeneRIF Biological Term Annotations	1.0	null
BRD-K83877780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01543
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860277
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12667
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.832484
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838051
heterotrimeric g-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.362422
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291365
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31928
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02236
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55071
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6566
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1299	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54078
PC3	CCLE Cell Line Gene Expression Profiles	1.0	2.13706
abnormal lung morphology	MPO Gene-Phenotype Associations	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.927
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47472
EGR1	ENCODE Transcription Factor Targets	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K60024823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24385
KLF5_KO_GDS3509_553_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
pleura	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19597
Brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
Atypical Fibroxanthoma Of Skin	DisGeNET Gene-Disease Associations	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10928
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48626
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999619
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2621
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29142
KYM1	DepMap CRISPR Gene Dependency	1.0	2.42599
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49863
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963534
HUH1	DepMap CRISPR Gene Dependency	1.0	2.64656
HPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
Habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05343
GTEX-T6MO-1726-SM-33HB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40747
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0633
BRD-K86019347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59756
leflunomide-7238	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963234
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.907229
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23257
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870571
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_162_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8384
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23098
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062069
BRD-K54898824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60332
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38326
positive regulation of inflammatory response	GO Biological Process Annotations 2025	1.0	null
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041565
G361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3658
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910868
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09872
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_81_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936209
Mono-Mac-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.51104
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73757
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2014	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
hsa-miR-4799-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
8-azaguanine-7444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60271
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34146
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
Perturb_5526_KO_Crtc1_SRP279598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.9359
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378372
Perturb_11872_KO_lincRNACox2_SRP120127	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.66751
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05381
activities	GeneRIF Biological Term Annotations	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29897
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056779
Inner medullary collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	3.96508
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09505
BRD-K62555617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81231
abnormal skin morphology	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC251	DepMap CRISPR Gene Dependency	1.0	2.40681
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02667
intermediate stratum of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0643
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070844
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
regulation of inflammatory response	GO Biological Process Annotations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19A-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91413
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
Inflammation	CTD Gene-Disease Associations	1.0	1.49356
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_42_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6474-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35602
GTEX-REY6-0926-SM-48FDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828623
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.505102
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051849
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20673
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63436
LNZ308	DepMap CRISPR Gene Dependency	1.0	2.40941
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1694
BRD-K99097591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41515
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7596
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.297447
BRD-K33986892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47222
Aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.027
parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365095
AE-51-ZO26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203977
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCAT	MSigDB Cancer Gene Co-expression Modules	1.0	null
Gastrin-CREB signalling pathway via PKC and MAPK	Reactome Pathways 2014	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08984
hsa-miR-4691-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26704
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
Sarcoma_SARC_TCGA-3B-A9HI-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8944
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00861
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36845
BRD-K16411174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29881
LRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41948
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
splenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240216
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04283
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
SNU478	DepMap CRISPR Gene Dependency	1.0	3.96462
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
Chondrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
BRD-K53634892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00559
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34185
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A24223049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61921
BRD-K82791632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0933
Perturb_14834_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.89155
GSE133516_5_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16267084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30432
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.514
pirenzepine-2071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34472
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
bromocriptine-1925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.452
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
CJM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47147
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58255
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21126
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	1.64947
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37973
BRD-K66089377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45056
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16298
HCA1	DepMap CRISPR Gene Dependency	1.0	3.86408
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922395
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
regulation of cell adhesion	GO Biological Process Annotations 2023	1.0	null
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurological pain disorder_CNS - Spinal Cord (MMHCC)_GSE18803	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.622852
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00442
positive regulation of Ras protein signal transduction	GO Biological Process Annotations 2023	1.0	null
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35561
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.17819
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
hsa-miR-4766-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
tanespimycin-1225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77759
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892041
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.84001
SRSF9_02_134	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27726
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K72700187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06258
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60542
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14075
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.34845
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.805
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885971
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8105-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal kidney cortex morphology	MPO Gene-Phenotype Associations	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.865199
regulators	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990684
amylocaine-1909	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69035249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13997
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19127
maintaining	GeneRIF Biological Term Annotations	1.0	null
HUPT4	DepMap CRISPR Gene Dependency	1.0	2.55356
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal renal glomerulus morphology	MPO Gene-Phenotype Associations	1.0	null
Midline group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3237
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878144
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.2299
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45141
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
BRD-K56572622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57247
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.61515
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162306
mantle zone of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04372
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857982
8505C	CCLE Cell Line Gene Expression Profiles	1.0	2.62565
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899028
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5568
BRD-K58025976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56505
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54510565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04434
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4539
BRD-K35088248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01132
BRD-K86773205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08065
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01951
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	1.0	1.52638
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.5581
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
GTEX-X8HC-0226-SM-4E3K1	GTEx Tissue Sample Gene Expression Profiles	1.0	3.08667
OPM1	CCLE Cell Line Gene CNV Profiles	1.0	1.8718
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07619
BRD-K32259584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68024
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.936786
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
Perturb_15070_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.1498
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23148
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09307
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056294
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865811
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956625
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.350001
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7397
Squamous cell carcinoma_Lung Tissue_GSE1987	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.472619
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19329
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892289
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907116
BRD-K68424387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61429
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86055
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.32905
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.722
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29498
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K01615696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07653
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.328332
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48518
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-578	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K17627540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30071
Perturb_12749_KO_Per1/Per2_SRP315570	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.10203
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H716	GDSC Cell Line Gene Expression Profiles	1.0	2.18267
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303919
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4905-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12089436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07429
GDF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33704
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC4850258__F5	PFOCR Pathway Figure Associations 2024	1.0	null
campprotein	GeneRIF Biological Term Annotations	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77633
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5514
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09775
BRD-A61864215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1859
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20987
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
accumulation	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61028
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11369
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79562
efo21	HPA Cell Line Gene Expression Profiles	1.0	1.5493
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.444499
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	2.69718
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00251
ZNF57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19387
Sudden infant death syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5615
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
HLMVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79955
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.0107
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849563
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09165
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30708
GTEX-T8EM-1126-SM-3DB7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42631
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.583
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.797708
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K09414286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40009
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
BRD-K94385157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4494
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57471
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963078
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
16195754-table2	GeneSigDB Published Gene Signatures	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81535
CDS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64375
BRD-A94366206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30408
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HUVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.52
Catecholaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-642a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
decreased angiogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25921
BRD-K55766625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42849
hemoperitoneum	MGI Mouse Phenotype Associations 2023	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.98658
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCNA-p21 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842943
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0869
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
sphingosylphosphorylcholine	GeneRIF Biological Term Annotations	1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878167
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine leiomyoma_Uterus_GSE2725	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.51673
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08887
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40661
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66698
fallopian tube	HPA Tissue Protein Expression Profiles	-1.0	-1.61515
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20673
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217762
petechiae	MGI Mouse Phenotype Associations 2023	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12703
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25732
BRD-A42030853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16165
muscle phenotype	MPO Gene-Phenotype Associations	1.0	null
SK-LMS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.87313
GTEX-UPK5-2326-SM-3P5Z8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864437
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97337407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2517
RAI14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88474
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5334-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23526
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99396
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13004
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90492
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02395
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19714
inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05437
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT4-19710469-TH1 cell mouse-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
tdag8	GeneRIF Biological Term Annotations	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4755
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2176
CREB3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20657
G protein-coupled receptor 4 orphan	InterPro Predicted Protein Domain Annotations	1.0	null
brain endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193928
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943838
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.489
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71164
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58606467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05482
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.58667
GTEX-WXYG-0926-SM-3NB2O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27635
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_63_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
upregulation	GeneRIF Biological Term Annotations	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.307033
BRD-K17610834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7032
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62163
BRD-K32535831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15876
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TP53_01_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.50579
BRD-K27476975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80673
BRD-K67525206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11804
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49399
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
AMO1	DepMap CRISPR Gene Dependency	1.0	2.8149
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32648
BRD-K71671197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87044
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29678
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06068
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90441
RBFOX2_02_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
BRD-K00414849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0072
BRD-K66253082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45537
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75833
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07363
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242398
proteincoupled	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.819434
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02107
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849563
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881565
EFNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5899
PMC3109512__F3	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970246
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51543
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48175
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5316868__F2	PFOCR Pathway Figure Associations 2023	1.0	null
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.76844
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058757
KLF4	ChEA Transcription Factor Targets	1.0	null
previously	GeneRIF Biological Term Annotations	1.0	null
BRD-K27374902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92203
neonatal lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
ITGA7_OE_GDS3209_142_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04109
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841563
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1628
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933979
PMC4728380-ncomms10153-s8.xlsx-High_affinity_MYC_Targets-Unnamed_0_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03195
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2514
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87647
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35744
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.348725
lung	GTEx Tissue Gene Expression Profiles	1.0	1.16551
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04847
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AM38	CCLE Cell Line Gene Expression Profiles	1.0	1.70671
acid	GeneRIF Biological Term Annotations	1.0	null
BRAF_knockdown_193_GSE5481	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.89141
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8837
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
NMuMg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899683
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48518
BRD-K00048155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43707
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70114
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84101
CORL88	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12743
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ivermectin-2051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.565
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08028
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60726
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LB647-SCLC	GDSC Cell Line Gene Expression Profiles	1.0	1.78524
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06787
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85555
IL9	MSigDB Cancer Gene Co-expression Modules	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831121
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKLMS1	CCLE Cell Line Gene Expression Profiles	1.0	2.01679
bendroflumethiazide-3415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53612850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47521
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
suggested	GeneRIF Biological Term Annotations	1.0	null
kinase	GeneRIF Biological Term Annotations	1.0	null
Osteopetrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.42485
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058174
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A47615980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12848
Vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.741
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36408
Necrosis	CTD Gene-Disease Associations	1.0	1.57474
UW228-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31236
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46132
Congenital central hypoventilation syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.209
positive regulation of defense response	GO Biological Process Annotations 2025	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85599
Perturb_9219_KO_Mecp2_SRP056141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.8601
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361155
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27438
vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.879089
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99409
Perturb_3733_KO_Trp53_SRP296860	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.03152
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38738
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86982
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705993
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21328
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.350372
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59126
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
increased urine phosphate level	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25936
mantle zone of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08566
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.3973
BRD-K03470412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77036
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881143
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55927371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22584
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73254
pleural fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347778
PMC1539153__F6	PFOCR Pathway Figure Associations 2023	1.0	null
Urease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.999
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046794
syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050902
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889817
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13581
stomach	HPA Tissue Protein Expression Profiles	1.0	0.776546
Perturb_8537_KO_Notch2_SRP152804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.4651
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15829
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90039
NCIH1339	CCLE Cell Line Gene CNV Profiles	1.0	1.37378
EP300	ENCODE Transcription Factor Targets	1.0	null
H3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23516
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97128200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6194
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
nmumg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.637999
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061705
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14949
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29856
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6616
Lung squamous cell carcinoma_LUSC_TCGA-56-7731-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93875187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31595
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91227
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cyanosis	MGI Mouse Phenotype Associations 2023	1.0	null
PF-00562151-00-5922	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Habenular trigone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7119
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53031
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71656
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826442
transmigration	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979524
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.16953
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03096
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.842773
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
BRD-K01225247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48149
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81379
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832921
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15016
Perturb_1263_KO_Mll3_SRP352738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.86169
BRD-K57244822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96368
LMSU	CCLE Cell Line Gene Expression Profiles	1.0	1.54877
pentamidine-4396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.897745
BRD-A96334094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24395
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38344
BRD-K54260552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47148
Sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
Subparafascicular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04791
BRD-K88934376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75109
GSE150032,GSE181873_3_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16742
GTEX-SNOS-0426-SM-32PMH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00732
abnormal cardiovascular development	MPO Gene-Phenotype Associations	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09138
GTEX-TKQ1-1126-SM-4GIAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18554
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21983
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
Sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64358
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891662
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04694
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28485
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.170283
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09777
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16551
BRD-K51215422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64403
BRD-A34492468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25473
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22196
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
Connecting tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850978
BRD-K43566466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02467
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931993
BRD-K13267130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16879
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890602
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67208
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01317
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92939
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27329
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37805
Carotid sinus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54299
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53903
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87224
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963234
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UMUC5	DepMap CRISPR Gene Dependency	1.0	4.70856
membrane	GO Cellular Component Annotations 2015	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00961
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31485
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360409
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
BRD-K34026318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48624
myotonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.459373
GSE196962_4_v_1_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49624
cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.362422
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.926479
3T3-Swiss albino cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17736
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
increased urine ammonia level	MGI Mouse Phenotype Associations 2023	1.0	null
MAN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1194
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21003
BRD-K70343553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.69122
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57823
KDM1A_KD_GDS5055_457_mouse_adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
positive regulation of defense response	GO Biological Process Annotations 2023	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K74251295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73666
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39265
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29427
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37157
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2308
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	2.09746
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5355-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Z-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36766
BRD-K00914921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2786
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38354
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thyroid	GTEx Tissue Gene Expression Profiles	1.0	0.907376
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31765
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.700671
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953135
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2803
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853823
MDAMB361	DepMap CRISPR Gene Dependency	1.0	3.44436
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80403
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2803
TRAMP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78366
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909421
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19324
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76395
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	Reactome Pathways 2014	1.0	null
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25884
critical	GeneRIF Biological Term Annotations	1.0	null
PMC4989457-13073_2016_339_MOESM9_ESM.xls-MITF_Q1_vs_Q4-Gene_id_HUGO_ID_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227186
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897193
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133255
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97284
decreased tumor growth/size	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82969
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
BRD-K25045770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32216
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858164
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11694
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88138
GTEX-T2IS-0226-SM-32QPH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84018
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54629
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23901
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02612
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Huelle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48227
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856689
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53046137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13871
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4493
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15187
regulation of inflammatory response	GO Biological Process Annotations 2025	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37691
BRD-A82843133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64499
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.4031
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.81192
ES2	CCLE Cell Line Gene Expression Profiles	1.0	1.3631
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90251
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5168-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA0040	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78191
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.301976
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44223
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63001
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AtT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31157
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1056
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.41598
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55486
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58128
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
PMC10331420-NIHMS1908116-supplement-supplemental_figures_files_included.pdf-11-ZNF263_ZNF263	Rummagene Transcription Factor Associations 2026	1.0	null
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20954
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51736
SIN3A	ENCODE Transcription Factor Targets	1.0	null
BRD-K26194226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41047
cardiovascular system phenotype	MPO Gene-Phenotype Associations	1.0	null
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
Glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919009
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.964882
AR	ChEA Transcription Factor Targets	1.0	null
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CCDC153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52988
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13088
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834496
medial group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40179
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.67021
Preosteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.02949
Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
halfmaximal	GeneRIF Biological Term Annotations	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08887
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_0Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.6228
BRD-K78959251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42833
CHD2	ENCODE Transcription Factor Targets	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35296
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10441
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1694
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09031
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574816
NCIH1975	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326798
respiratory distress	MPO Gene-Phenotype Associations	1.0	null
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61137
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93032
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.02604
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64007
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06284
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.5471
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967854
BRD-K07928699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27798
apomorphine-1923	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74642
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052604
PMC9437808-mmc3.xlsx-IPA_Upstream_regulators-IPA_Upstream_regulator_analysis_Up_regulated_genes_following_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_0_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04206
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3414_OE_Zeb2_SRP072845	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.36706
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850569
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26976202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27453
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853415
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_75_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07688551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09345
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05576
GTEX-S4P3-1326-SM-4AD6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859026
GPCR downstream signalling	Reactome Pathways 2024	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58993
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_84_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3619
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4815
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22393
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09815
DCC	MSigDB Cancer Gene Co-expression Modules	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01688
amp	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056752
GSE196962_2_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66439
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.90276
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323874
BRD-K86371068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60023
Merkel Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K83125173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16994
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8973
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7548
BRD-K44401972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08551
BRD-K48629186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28392
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0479
ZNF415	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93936
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
PMC4697456__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22196
spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223906
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	1.5177
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089372
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25883
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79562
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4728-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
glomerulus hemorrhage	MGI Mouse Phenotype Associations 2023	1.0	null
PCTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42512
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7988
BRD-K93410934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02276
Umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7612
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32755
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922395
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388158
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15587
7-aminocephalosporanic acid-4826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24248
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974308
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal blood vessel morphology	MPO Gene-Phenotype Associations	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2803
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95993
BRD-K11804865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73503
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47325
Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5665
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29307
FOSL1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870118
BRD-K33979719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25364
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994546
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76183
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day1-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.84716
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71801
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
r1 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04372
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65338
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
GSE203158_12_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A52475911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68053
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06456
Lung adenocarcinoma_LUAD_TCGA-50-5933-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
right	GeneRIF Biological Term Annotations	1.0	null
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34596
GTEX-R55D-0326-SM-48FES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50523
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03787
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04203
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66483
HEY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	1.51559
Medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.45
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842799
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0071
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49361
Benign Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_30_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47038
Maple Syrup Urine Disease	DisGeNET Gene-Disease Associations	1.0	null
CEBPZOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45379
responses	GeneRIF Biological Term Annotations	1.0	null
proxyphylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18201
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.83254
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0699