association	dataset	threshold value	standardized value
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.638
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.92173
Cerebrovascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
Borderline Personality Disorder	DisGeNET Gene-Disease Associations	1.0	null
microphthalmia	MGI Mouse Phenotype Associations 2023	1.0	null
abnormal kidney morphology	MGI Mouse Phenotype Associations 2023	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9199
Autism	DisGeNET Gene-Disease Associations	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.775249
Pseudomyxoma Peritonei	DisGeNET Gene-Disease Associations	1.0	null
showing	GeneRIF Biological Term Annotations	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Hypomagnesemia	DisGeNET Gene-Phenotype Associations	1.0	null
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.3922
Hormone Refractory Prostate Cancer	DisGeNET Gene-Disease Associations	1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.742806
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4116
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75626
Marijuana Abuse	DisGeNET Gene-Disease Associations	1.0	null
Right colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Flp-In-T-REx cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
Carney Complex	DisGeNET Gene-Disease Associations	1.0	null
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
abnormal sympathetic neuron innervation pattern	MGI Mouse Phenotype Associations 2023	1.0	null
gpr42	GeneRIF Biological Term Annotations	1.0	null
rather	GeneRIF Biological Term Annotations	1.0	null
Taste Sweet	DisGeNET Gene-Phenotype Associations	1.0	null
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.843069
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.912
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0504
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8843
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.17259
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.922221
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Leukemogenesis	DisGeNET Gene-Disease Associations	1.0	null
Nerve plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
Tumor Initiation	DisGeNET Gene-Phenotype Associations	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-576-ZNF688_ZNF688	Rummagene Transcription Factor Associations 2026	1.0	null
smoothmuscle_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.33145
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
Memory Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Endometrial Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Squamous Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Total Hypotrichosis, Mari Type	DisGeNET Gene-Disease Associations	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.559
Pseudohypoparathyroidism	DisGeNET Gene-Disease Associations	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.64
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Acrodyostosis	DisGeNET Gene-Disease Associations	1.0	null
decreased circulating leptin level	MGI Mouse Phenotype Associations 2023	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5402
Adrenocortical Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-634-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.359
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.746
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
Chronic Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Idiopathic Hypogonadotropic Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	201.377
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2909
decreased liver triglyceride level	MGI Mouse Phenotype Associations 2023	1.0	null
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
Renal Sclerosis With Hypertension	DisGeNET Gene-Disease Associations	1.0	null
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.75
Malaria	DisGeNET Gene-Disease Associations	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.4566
Forgetful	DisGeNET Gene-Phenotype Associations	1.0	null
Benign Prostatic Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
Multiple Myeloma	DisGeNET Gene-Disease Associations	1.0	null
Erythroleukemia (Erythroid/Myeloid)	DisGeNET Gene-Disease Associations	1.0	null
Autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.717
Left Ventricular Hypertrophy	DisGeNET Gene-Disease Associations	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
Genetic Hypertension	DisGeNET Gene-Disease Associations	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
Priapism	DisGeNET Gene-Disease Associations	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4763
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
Triple Negative Breast Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
Food allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
Lewy neurite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2365
Familial (Fpah)	DisGeNET Gene-Disease Associations	1.0	null
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
Intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.486
increased circulating insulin level	MGI Mouse Phenotype Associations 2023	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.5322
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5509
Skin Endocrine Disorder	DisGeNET Gene-Disease Associations	1.0	null
NCI-H716 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
PMC11956947-media-4.xlsx-C_GSEA_gene_sets-TGAYRTCA_ATF3_Q6_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Von Willebrand Disease	DisGeNET Gene-Disease Associations	1.0	null
small superior cervical ganglion	MGI Mouse Phenotype Associations 2023	1.0	null
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.924826
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0542
Papillary Thyroid Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
abnormal energy homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Ulcerative Colitis	DisGeNET Gene-Disease Associations	1.0	null
Endometriosis	DisGeNET Gene-Disease Associations	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.902685
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
Childhood Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Paget Disease	DisGeNET Gene-Disease Associations	1.0	null
Catecholaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
Hypoglycemia	DisGeNET Gene-Disease Associations	1.0	null
Colonic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0592
Rhinovirus Infection	DisGeNET Gene-Disease Associations	1.0	null
appendix	HPA Tissue Gene Expression Profiles	1.0	1.18994
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Osteitis	DisGeNET Gene-Disease Associations	1.0	null
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
Mccune-Albright Syndrome	DisGeNET Gene-Disease Associations	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.868615
Hereditary Hemochromatosis	DisGeNET Gene-Disease Associations	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.579
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Platelet alpha granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
decreased oxygen consumption	MGI Mouse Phenotype Associations 2023	1.0	null
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.069
abnormal adipose tissue physiology	MGI Mouse Phenotype Associations 2023	1.0	null
Childhood Acute Lymphoblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3566
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
Rickets	DisGeNET Gene-Disease Associations	1.0	null
NCI-H226Br cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.65
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
abnormal feces composition	MGI Mouse Phenotype Associations 2023	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-IRF6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
Neuralgia	DisGeNET Gene-Phenotype Associations	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
Gastric juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
blood	GTEx Tissue Gene Expression Profiles	1.0	1.57855
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5944
decreased body temperature	MGI Mouse Phenotype Associations 2023	1.0	null
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.925
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4878
Acth-Independent Macronodular Adrenal Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
Meningeal Melanoma	DisGeNET Gene-Disease Associations	1.0	null
Acute Erythroblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46789
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.64853
abnormal heart rate	MGI Mouse Phenotype Associations 2023	1.0	null
Bronchial smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
Kidney Calculi	DisGeNET Gene-Disease Associations	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31682
Intestinal T-Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
Gut wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.7311
Anxiety	DisGeNET Gene-Phenotype Associations	1.0	null
decreased physiological sensitivity to xenobiotic	MGI Mouse Phenotype Associations 2023	1.0	null
Vibratory Urticaria	DisGeNET Gene-Disease Associations	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.666549
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.758
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8075
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59499
Glioma	DisGeNET Gene-Disease Associations	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7996
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.81952
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Left colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8894
Experimental Organism Basal Cell Carcinoma	DisGeNET Gene-Phenotype Associations	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Anophthalmia And Pulmonary Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	0.910227
Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8673
Conventional (Clear Cell) Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6304
Adult Erythroleukemia	DisGeNET Gene-Disease Associations	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.2275
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_CBCTGACGTCANCS_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
skin	HPA Tissue Gene Expression Profiles	-1.0	-1.02652
Retinoid Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
abnormal noradrenaline level	MGI Mouse Phenotype Associations 2023	1.0	null
Huntington Disease	DisGeNET Gene-Disease Associations	1.0	null
six	GeneRIF Biological Term Annotations	1.0	null
Rmz	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.15596
Depression	DisGeNET Gene-Disease Associations	1.0	null
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	0.930433
Humoral Hypercalcemia Of Malignancy (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
Gut cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4701
Adrenal Cushing'S Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Recurrent Tumor	DisGeNET Gene-Phenotype Associations	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8931
Aortic Valve Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.26896
acid	GeneRIF Biological Term Annotations	1.0	null
Malignant tumor of pancreas_saliva_GSE14245	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49982
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26851
Squamous Cell Carcinoma Of Skin	DisGeNET Gene-Disease Associations	1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tetralogy Of Fallot	DisGeNET Gene-Disease Associations	1.0	null
Bronchopulmonary Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
Tick Fever	DisGeNET Gene-Disease Associations	1.0	null
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79558
Retinoblastoma	DisGeNET Gene-Disease Associations	1.0	null
Tumor Angiogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
increased circulating ketone body level	MGI Mouse Phenotype Associations 2023	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
APUD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.014
Adult Acute Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Bulimia	DisGeNET Gene-Disease Associations	1.0	null
T-84 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
Gastrointestinal allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
Atypical Ductal Breast Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5841
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8399
Ischemic Stroke	DisGeNET Gene-Disease Associations	1.0	null
Inflammatory Pain	DisGeNET Gene-Phenotype Associations	1.0	null
Triple-Negative Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Blastoma	DisGeNET Gene-Disease Associations	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.60179
Kaposi Sarcoma	DisGeNET Gene-Disease Associations	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2414
Adult Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5615
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Small intestine mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86582
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7168
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4717
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8666
Depression	DisGeNET Gene-Phenotype Associations	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0217
Polyps	DisGeNET Gene-Phenotype Associations	1.0	null
small liver	MGI Mouse Phenotype Associations 2023	1.0	null
Nociceptive Pain	DisGeNET Gene-Phenotype Associations	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9321
Depressed Mood	DisGeNET Gene-Phenotype Associations	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal digestion	MGI Mouse Phenotype Associations 2023	1.0	null
Atherothrombosis	DisGeNET Gene-Disease Associations	1.0	null
PMC11956947-media-4.xlsx-C_GSEA_gene_sets-ATF3_Q6_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Primary Effusion Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic Ductal Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
PMC12405457-41467_2025_63629_MOESM3_ESM.xlsx-Gene_Pair_List_LOC-GATA1_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
Fibrous Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	179.21
Enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.015
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hirschsprung Disease	DisGeNET Gene-Disease Associations	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7327
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7829
Enteropathy-Associated T-Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
Multiple Chronic Conditions	DisGeNET Gene-Disease Associations	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
Complete Trisomy 21 Syndrome	DisGeNET Gene-Disease Associations	1.0	null
gpr41	GeneRIF Biological Term Annotations	1.0	null
genespecific	GeneRIF Biological Term Annotations	1.0	null
Thyroid Nodule	DisGeNET Gene-Disease Associations	1.0	null
Colonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.006
Gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.694
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Hypoparathyroidism	DisGeNET Gene-Disease Associations	1.0	null
Multiple Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
abnormal sympathetic neuron physiology	MGI Mouse Phenotype Associations 2023	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3169
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.653
amino	GeneRIF Biological Term Annotations	1.0	null
Urease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
Irritable bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6418
Precursor B-Cell Lymphoblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Cholestatic Pruritus	DisGeNET Gene-Phenotype Associations	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.61
Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
496100660_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20206
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Sympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.526
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.394
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8638
Carcinoma, Basal Cell	DisGeNET Gene-Disease Associations	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1002
NLRP6 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
evidence	GeneRIF Biological Term Annotations	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1525
Hypercholesterolemia	DisGeNET Gene-Disease Associations	1.0	null
Withdrawal Symptoms	DisGeNET Gene-Phenotype Associations	1.0	null
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Cerebrovascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
PMC3348545-NIHMS263168-supplement-3.pdf-385-ZNF181_ZNF181	Rummagene Transcription Factor Associations 2026	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9899
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0855
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0204
appendices_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.80735
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6826
Ruminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7177
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4057
Ocular Albinism	DisGeNET Gene-Disease Associations	1.0	null
Kallmann Syndrome	DisGeNET Gene-Disease Associations	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3171
Nephrogenic Diabetes Insipidus	DisGeNET Gene-Disease Associations	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4231
Endothelial Dysfunction	DisGeNET Gene-Phenotype Associations	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Thyroid Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
Cannabis Dependence	DisGeNET Gene-Disease Associations	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.31778
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2719
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2
Tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.739
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
Portal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
chr19_35374928_A_G_b38	GTEx eQTL 2025	1.0	1.0364
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56204
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
NCI-H727 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
rw174	GeneRIF Biological Term Annotations	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1902
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6367
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_TGAYRTCA_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2451
Diarrhea	DisGeNET Gene-Phenotype Associations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-2.10016
appendices_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.828529
esophagus	HPA Tissue Gene Expression Profiles	-1.0	-1.02652
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
Autosomal Dominant Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
Flushing	DisGeNET Gene-Phenotype Associations	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9844
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6032
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Conn Adenoma	DisGeNET Gene-Disease Associations	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0766
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94703
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
Sympathetic chain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.31185
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	0.919065
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0835
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9537
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.765
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0788
Hypotrichosis	DisGeNET Gene-Disease Associations	1.0	null
Intracranial vasospasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3478
Heartburn	DisGeNET Gene-Phenotype Associations	1.0	null
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cystic Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Cholestasis	DisGeNET Gene-Disease Associations	1.0	null
trans-synaptic protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.278
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2833
Obesity	DisGeNET Gene-Disease Associations	1.0	null
Mental Depression	DisGeNET Gene-Disease Associations	1.0	null
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
Schizoaffective Disorder	DisGeNET Gene-Disease Associations	1.0	null
Gut mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7447
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0455
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7905
mopc31c	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0861
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
GSE162015_1_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0259
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
Colonic epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
Cecum cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
presents	GeneRIF Biological Term Annotations	1.0	null
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3328
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
Bronchial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
Gastrointestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.949618
Primary Pigmented Nodular Adrenal Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
abnormal intestine physiology	MGI Mouse Phenotype Associations 2023	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.86035
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Epithelial Ovarian Cancer	DisGeNET Gene-Disease Associations	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.9507
Pulmonary Cystic Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
Renin Induced Hypertension	DisGeNET Gene-Disease Associations	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.711
breast	GTEx Tissue Gene Expression Profiles	1.0	0.837395
Irritable Bowel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Angiogenic Switch	DisGeNET Gene-Disease Associations	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79019
Ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.646
Autosomal Dominant Hypocalcemia	DisGeNET Gene-Disease Associations	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
Primary Pigmented Nodular Adrenocortical Disease	DisGeNET Gene-Disease Associations	1.0	null
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
5-lipoxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2612
GATA1	ChEA Transcription Factor Targets	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
fat_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.24898
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.6625
Essential Hypertension	DisGeNET Gene-Disease Associations	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2981
abnormal oxygen consumption	MGI Mouse Phenotype Associations 2023	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Herpes Nos	DisGeNET Gene-Disease Associations	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
Graves Disease	DisGeNET Gene-Disease Associations	1.0	null
decreased heart rate	MGI Mouse Phenotype Associations 2023	1.0	null
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
impaired glucose tolerance	MGI Mouse Phenotype Associations 2023	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5933
PHA granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4643
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4746
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2495
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Nephrolithiasis	DisGeNET Gene-Disease Associations	1.0	null
Gut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.619
Uveal Melanoma	DisGeNET Gene-Disease Associations	1.0	null
chr19_35354837_A_T_b38	GTEx eQTL 2025	1.0	1.01716
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5483
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.910424
Postural Orthostatic Tachycardia Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0015
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.818604
placenta_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.37485
Squamous Cell Carcinoma Of The Head And Neck	DisGeNET Gene-Disease Associations	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-Genes_with_ATF3_combined_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Attention Deficit Disorder	DisGeNET Gene-Disease Associations	1.0	null
GSE162015_2_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Polyphosphate kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7455
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8933
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.01039
Infection By Babesia Bovis	DisGeNET Gene-Disease Associations	1.0	null
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nephrogenic Syndrome Of Inappropriate Antidiuresis	DisGeNET Gene-Disease Associations	1.0	null
enlarged kidney	MGI Mouse Phenotype Associations 2023	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4247
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2152
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5807
Hyperactive Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4221
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.72
17284527-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3091
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
Down Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
Agnosia	DisGeNET Gene-Disease Associations	1.0	null
Curli	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
abnormal eye morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Mood Swings	DisGeNET Gene-Disease Associations	1.0	null
Meconium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
GATA1-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4056
abnormal liver morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.42278
Down Syndrome Critical Region	DisGeNET Gene-Disease Associations	1.0	null
Secondary Malignant Neoplasm Of Bone	DisGeNET Gene-Disease Associations	1.0	null
Ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.534
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8662
PMC12405457-41467_2025_63629_MOESM3_ESM.xlsx-Gene_Pair_List_LOC-CEBPE_CEBPE	Rummagene Transcription Factor Associations 2026	1.0	null
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Intestinal wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.314
Acute Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Adult T-Cell Lymphoma/Leukemia	DisGeNET Gene-Disease Associations	1.0	null
L-929 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.542
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7201
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
Endotoxemia	DisGeNET Gene-Phenotype Associations	1.0	null
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
Bacterial biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
Chronic Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.04277
Asthma	DisGeNET Gene-Disease Associations	1.0	null
Enteric nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.466
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fatty Liver	DisGeNET Gene-Disease Associations	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7087
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0771
Childhood Leukemia	DisGeNET Gene-Disease Associations	1.0	null
differences	GeneRIF Biological Term Annotations	1.0	null
Gastrointestinal endocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.011
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Hydrops Fetalis, Non-Immune	DisGeNET Gene-Disease Associations	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hereditary Sensory Autonomic Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
Familial Benign Hypercalcemia	DisGeNET Gene-Disease Associations	1.0	null
Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal intestinal transit time	MGI Mouse Phenotype Associations 2023	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8639
Intestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.431
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8034
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4024
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1324
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.976
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9517
decreased epididymal fat pad weight	MGI Mouse Phenotype Associations 2023	1.0	null
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.399
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09006
Bartter Disease	DisGeNET Gene-Disease Associations	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Differentiated Thyroid Gland Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Intestinal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
decreased circulating noradrenaline level	MGI Mouse Phenotype Associations 2023	1.0	null