association	dataset	threshold value	standardized value
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36686
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.58096
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43073
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12911
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.745
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26446
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898869
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185477
parkinsonism	GWASdb SNP-Phenotype Associations	1.0	0.440463
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32399
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10426
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09064
APTO-253_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0224425
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54212
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53832
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.1434
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.1832
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833081
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
osteosclerosis of the ulna	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962887
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95028
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46961
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0077
abnormality of forearm bone	GWASdb SNP-Phenotype Associations	1.0	0.881236
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.57888
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42195
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.882768
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Corpus allatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
reproductive system disease	GWASdb SNP-Disease Associations	1.0	0.175886
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883496
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889454
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832138
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1854
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00843
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08152
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9597
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7068
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69508
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09751
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841201
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39323
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1737
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23704
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.80788
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22938
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.880593
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
7515_RPS26_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.513951
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10755
SEBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.469
GPX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27992
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43902
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10478
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00668
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47581
A549_Ofloxacin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141008
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23149
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08206
GSE209973_1_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-84-PK04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209922
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85319
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996231
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0303
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854387
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39957
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64366
High light scatter reticulocyte percentage of red cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54239
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06564
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826895
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the ulna	GWASdb SNP-Phenotype Associations	1.0	0.881236
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302888
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25951
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2987
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1232
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17302
OB-06-WW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333024
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22938
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.84138
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
FE-94-WT30_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223975
A549_Ofloxacin_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111494
abnormality of head or neck	GWASdb SNP-Phenotype Associations	1.0	0.190763
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Superior mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
abnormality of male external genitalia	GWASdb SNP-Phenotype Associations	1.0	0.267827
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09681
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997328
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Mean corpuscular hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89866
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28698
Adrenocortical cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830343
imidazoleglycerol-phosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73895
glomerulosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993697
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953969
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15325
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22702
GSE99687_3_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.664
Emphysema annual change measurement in smokers (adjusted lung density)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
Tranilast_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0121536
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38812
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834357
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877175
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.1486
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56407
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01196
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45107
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26016
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38994
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33453
nephrosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20043
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55408
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47936
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70452
increased bone mineral density	GWASdb SNP-Phenotype Associations	1.0	0.881236
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	2.51935
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59563
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.49861
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01363
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09804
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.311672
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59651
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62482
A549_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164408
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.075
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38224
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T-tubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HOXA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33527
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25908
Daidzin_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0185506
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1184
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57456
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25335
disease	GWASdb SNP-Disease Associations	1.0	0.031978
RAB31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59346
LAMA84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56666
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82768
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70913
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69515
LY-2584702 (tosylate salt)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00666048
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4331
diaphyseal sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.75318
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988289
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26605
u698	HPA Cell Line Gene Expression Profiles	-1.0	-1.00674
Vinblastine (sulfate)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0137712
AZD1390_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0119051
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
6946_PTTG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.669669
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4733
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830915
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.946944
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831613
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39007
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888133
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of the metaphyses	GWASdb SNP-Phenotype Associations	1.0	0.881236
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49925
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885935
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62563
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52058
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61076
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893273
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34726
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16789
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47936
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10473
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25335
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954349
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274861
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.856439
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11119
Bacteroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
prostatic hypertrophy	GWASdb SNP-Disease Associations	1.0	0.871773
GSE73628_1_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40095
parkinson's disease	GWASdb SNP-Disease Associations	1.0	0.516361
GSE215086_1_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SF3B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64251
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150176
RAD21	ENCODE Transcription Factor Targets	1.0	null
K562_Mercaptopurine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149483
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858211
6455_PLK4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.502876
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41975
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33826
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933397
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841128
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972115
abnormality of phalanx of finger	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49402
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2788
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32883
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908264
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01223
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16343
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14963
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8351
KCTD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01492
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.212876
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327636
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983292
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38271
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02631
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55634
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34405
metaphyseal sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986408
A549_Celecoxib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01315
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240296
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
K562_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018409
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89866
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05396
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2672
abnormal axial skeleton morphology	GWASdb SNP-Phenotype Associations	1.0	0.385262
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56378
Pith	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09811
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997101
abnormality of the upper limb	GWASdb SNP-Phenotype Associations	1.0	0.694828
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30134
BF-49-KQ10_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294293
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4016
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975317
abnormality of macrophages	GWASdb SNP-Phenotype Associations	1.0	0.314563
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993273
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918581
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97586
Root hair tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08261
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16913
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2955
6906_PTER_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.528872
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40247
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40072
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89866
A549_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132979
abnormality of long bone morphology	GWASdb SNP-Phenotype Associations	1.0	0.881236
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40136
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07684
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63886
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22688
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916245
abnormal renal morphology	GWASdb SNP-Phenotype Associations	1.0	0.434607
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48203
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34474
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75197
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04937
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69421
SIN3A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10794847-mmc3.xlsx-PBRM1_KD_up-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24357
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33453
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964736
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Costamere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.837352
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4706
2792_EXOSC5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.509361
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4537
urethral stenosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13727
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13508
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1703
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2963
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10359
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19036
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.52469
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04495
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.951
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00313
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
APELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07539
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4355
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32349
5447_NADSYN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.637666
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33453
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44704
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08996
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40924
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06725
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67461
GSE215086_8_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160242
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07144
BC3C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61109
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09898
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5483
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23601
MKRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26735
MCF7_Barasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118061
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.09456
Biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3367
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16117
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14604
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878599
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33396
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75082
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Axillary bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.41
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932432
TA-20-FO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211545
male reproductive system disease	GWASdb SNP-Disease Associations	1.0	0.398597
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63428
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36474
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Luminespib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015294
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10659
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79377
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19418
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77484
A549_Decitabine_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127452
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.896388
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.07559
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FF-90-JK74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226787
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42303
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCCSUP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38989
6549_POLR2H_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.606574
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42341
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35343
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05745
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.03347
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Vinblastine (sulfate)_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0161576
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20589
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.500819
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.21194
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.942889
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04924
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20786
non-caseating epithelioid cell granulomatosis	GWASdb SNP-Phenotype Associations	1.0	0.765174
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18294
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995225
sclerosis of finger phalanx	GWASdb SNP-Phenotype Associations	1.0	0.881236
LJI308_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.024542
A549_G007-LK_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122506
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25979
Leaf axil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46767
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.179108
clavicular sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5617
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.22581
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KDM4A	ENCODE Transcription Factor Targets	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.1442
5587_NEDD8-MDP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.507701
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18917
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46103
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.981755
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21615
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.702651
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877133
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18942
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3895
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04324
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35913
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1441
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873643
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.065148
Visceral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
HTR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20506
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47901
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6773
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88851
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8102
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.019
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57341
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89381
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06122
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.08599
JUND	ENCODE Transcription Factor Targets	1.0	null
abnormality of the lower urinary tract	GWASdb SNP-Phenotype Associations	1.0	0.403971
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34358
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4965
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.034
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Chronotype	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Aliskiren_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0192879
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36262
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03012
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24922
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01732
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Vinblastine (sulfate)_SW 900	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0117853
Daytime nap	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4699
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17643
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02633
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913468
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03069
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10475
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45305
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66706
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06976
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38573
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41626
Benproperine (phosphate)_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0186843
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.113692
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
L428	CCLE Cell Line Gene CNV Profiles	1.0	1.41201
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21172
colon	HPA Tissue Protein Expression Profiles	-1.0	-0.723977
Proglumide_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0174784
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9669
AKAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67636
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978656
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38865
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40894
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04779
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8618
Elongin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.962
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74673
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.038
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25563
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10784
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16611
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60802
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55341
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932756
GTEX-XUZC-1226-SM-4BRVJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827475
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30444
ANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09908
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15212
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
K562_WP1066_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174037
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06134
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15542
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the forearm	GWASdb SNP-Phenotype Associations	1.0	0.881236
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226301
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.584
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25059
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anomaly of the upper limb diaphyses	GWASdb SNP-Phenotype Associations	1.0	0.881236
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3032
SNU324	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81226
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25114
costochondral joint sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.9369
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18831
GSE146982_3_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83482
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08932
abnormality of central motor function	GWASdb SNP-Phenotype Associations	1.0	0.440463
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04924
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06338
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08804
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181622
K562_TAK-901_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177984
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83648
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.06927
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.989
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00811
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60443
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926579
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27993
PMC12179407-MCO2-6-e70261-s004.xlsx-down_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14014
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01196
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19629
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22984
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07256
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927638
patchy sclerosis of radial diaphysis	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911305
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989324
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64671
sclerosis of skull base	GWASdb SNP-Phenotype Associations	1.0	0.881236
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14209
A549_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170327
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01928
Allantoin_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0174455
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02569
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16148
Mean reticulocyte volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.72218
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73005
anomaly of the limb diaphyses	GWASdb SNP-Phenotype Associations	1.0	0.881236
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.953767
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.618515
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879462
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09961
NCIH69	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
9972_ZBTB16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.540862
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74613
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-1.09854
Ankyrin repeat	InterPro Predicted Protein Domain Annotations	1.0	null
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42215
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Corpus cardiacum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
Femur bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
EE-32-EY37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240438
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34576
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61187
MAFF	ENCODE Transcription Factor Targets	1.0	null
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0407
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68054
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01583
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95582
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935345
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	0.853266
Cognitive decline rate in late mild cognitive impairment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03836
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51558
Dura mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
A-172 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89866
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21669
Fer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
Tadalafil_AN3 CA	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.019398
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832882
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91276
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872802
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172542
GTEX-RWS6-1726-SM-47JXP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926582
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893432
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16611
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877987
Hydroxyfasudil_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0384384
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13509
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
1578_CHML_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.607179
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89352
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the urethra	GWASdb SNP-Phenotype Associations	1.0	0.403971
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24338
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11666
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20194
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887891
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.946509
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903115
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7869
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.871
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950951
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16014
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933724
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16611
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Coronary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22614
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17213
2235_DKC1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.512137
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
A549_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172398
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2963
generalized osteosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863935
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71486
abnormality of limb bone morphology	GWASdb SNP-Phenotype Associations	1.0	0.881236
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11053
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925707
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924999
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97911
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66809
abnormality of the vertebral column	GWASdb SNP-Phenotype Associations	1.0	0.244301
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the ribs	GWASdb SNP-Phenotype Associations	1.0	0.881236
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-2.30927
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74223
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954349
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.29388
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42726
Methylthiouracil_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0140825
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33066
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09403
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70165
hsa-miR-4724-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Ofloxacin_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123765
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907066
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09178
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37113
BT549	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3494
Fumaric acid_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0261149
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	2.07482
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28623
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.113908
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92149
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853166
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	3.50833
SOCS protein, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870783
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3716
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10029_ZC3H8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.653025
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24738
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04462
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0494
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62888
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988734
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2955
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07411
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	1.37645
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4971
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43281
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.1486
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22601
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39173
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.835027
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75204
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870115
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05034
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904445
Bisoprolol (hemifumarate)_HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0221627
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6709
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72006
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.156
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992645
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07764
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05556
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50385
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872321
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4827
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11011
TAK-733_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0123696
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03824
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31961
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65729
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66938
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1597
Allantoin_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0406067
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.929459
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.02212
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.56387
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Peribacteroid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45091
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33705
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77737
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225095
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858132
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30636
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92425
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16676
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15235
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of extrapyramidal motor function	GWASdb SNP-Phenotype Associations	1.0	0.440463
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903456
abnormality of the vertebrae	GWASdb SNP-Phenotype Associations	1.0	0.881236
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866523
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1854
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32142
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.051285
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6304_PHLDB3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.556272
TTC30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2402
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.257
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.18006
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03546
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12663
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.22581
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Superficial temporal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
9420_TUBB_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.67927
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28556
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962758
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69212
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832083
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.140995
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Omeprazole_NCI-H596	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.051222
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20971
vh2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918452
EKVX	CCLE Cell Line Gene CNV Profiles	1.0	1.34168
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23213
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31003
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948383
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304424
CHD1	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32246
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.922458
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.89051
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
A549_XAV-939_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135438
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43971
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.501158
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825834
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.77435
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.113908
VCB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
GTEX-P78B-1126-SM-3P615	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951524
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
High light scatter reticulocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.81577
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27536
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-2.56786
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1854
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.88549
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5946
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25375
abnormality of the skull	GWASdb SNP-Phenotype Associations	1.0	0.486206
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.917706
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04233
MCF7_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0106616
FUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29894
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.929899
Root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
Vinblastine (sulfate)_HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0112021
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865957
Cytoplasmic ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3785
urethral sphincter sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
8040_SLC35A4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.561345
A549_MK-5108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152232
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26313
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.2349
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01196
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	3.03269
Naproxen_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0269457
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9444
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.6945
abnormality of the head	GWASdb SNP-Phenotype Associations	1.0	0.190763
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77179
abnormal diaphysis morphology	GWASdb SNP-Phenotype Associations	1.0	0.881236
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328004
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08685
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.830422
A549_JNJ-7706621_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127724
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04957
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.118111
MK-3903_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0212026
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950788
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870115
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86981
A549_Bisindolylmaleimide IX_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146897
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0023
NC-27-AD53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466618
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.203534
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40923
PMC11588066-pnas.2410331121.sapp.pdf-145-ZNF621_ZNF621	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10303
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11565
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9201
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.92175
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6373
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14891
abnormal appendicular skeleton morphology	GWASdb SNP-Phenotype Associations	1.0	0.721003
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10942
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16732
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75204
A549_Decitabine_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140868
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.840479
brain	HPA Tissue Gene Expression Profiles	1.0	1.50472
Phenytoin (sodium)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0281616
patchy changes of bone mineral density	GWASdb SNP-Phenotype Associations	1.0	0.881236
Ivermectin_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00790157
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22738
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00237
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bacterial biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06078
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.006
K562_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149711
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08865
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149359_3_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968895
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
8-Hydroxyquinoline_SW 900	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00594571
abnormality of the thorax	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980149
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15056
hsa-miR-543	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93511
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01334
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937068
Bimiralisib_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0212534
sclerosis of humeral diaphysis	GWASdb SNP-Phenotype Associations	1.0	0.881236
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GB-73-QS80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.602524
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.524063
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38629
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07078
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34447
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00271
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37106
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.04001
CREB1	ENCODE Transcription Factor Targets	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870115
Sunitinib_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0186908
efo21	HPA Cell Line Gene Expression Profiles	1.0	1.25369
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20415
K562_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153884
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2454
abnormality of bone mineral density	GWASdb SNP-Phenotype Associations	1.0	0.584073
GSE212848_1_v_0_pum1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954349
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65291
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839084
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38113
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6565
1789_COQ10A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.557416
5888_NUP155_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.835714
granulomatosis	GWASdb SNP-Phenotype Associations	1.0	0.348465
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5154
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34724
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9667_USP4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.647203
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44284
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16715
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3333
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8761
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.876333
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Root cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
K562_YM155_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166844
Sulfisoxazole_SW 900	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0196954
Neutrophil percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2301
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829629
GTEX-S3XE-0226-SM-4AD6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26514
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912649
sclerosis of foot bone	GWASdb SNP-Phenotype Associations	1.0	0.881236
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.850467
Alcohol consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13303
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03232
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880931
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62071
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43192
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1863
kidney	HPA Tissue Protein Expression Profiles	-1.0	-0.723977
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.917668
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14015
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990532
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.62947
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11244
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41456
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28414
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7425
A549_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159414
BICR56	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91977
22RV1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23803
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4492
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832951
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.60292
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844018
calvarial osteosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56475
Adult body size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34034
GTEX-XGQ4-1226-SM-4AT67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52627
abnormality of the glomerulus	GWASdb SNP-Phenotype Associations	1.0	0.486206
Systemising	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846042
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
A549_Prednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0197276
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03849
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
LNCAPCLONEFGC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87807
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.11873
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878359
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08101
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80835
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882941
abnormality of the radius	GWASdb SNP-Phenotype Associations	1.0	0.881236
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.87853
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01308
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951277
2988_FBL_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.626461
abnormality of the choroid	GWASdb SNP-Phenotype Associations	1.0	0.359395
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.21815
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3134
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.040512
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940159
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38234
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.368905
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879574
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40136
Bronchodilator response in asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16554
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
bacteroid-containing symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
Vitamin K4_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0134978
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10743
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20928
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37671
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6361
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31576
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.45192
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29353
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4197
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10521
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879759
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Interferon regulatory factor 7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.344
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14146
MDAPCA2B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01586
abnormality of the humeral diaphysis	GWASdb SNP-Phenotype Associations	1.0	0.881236
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12139
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225081
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12646
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08607
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25785
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.901408
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10027
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32067
SA-32-CC58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244326
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11627
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888102
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36764
diaphyseal sclerosis of the upper limbs	GWASdb SNP-Phenotype Associations	1.0	0.881236
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41921
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14557
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996598
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63418
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DA-58-LZ09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.516355
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64426
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94608
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
T47D	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35846
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57284
7893_SEM1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504488
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48538
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38125
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18831
synucleinopathy	GWASdb SNP-Disease Associations	1.0	0.516361
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45983
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7603
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.0529
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.845846
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85237
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
714_AURKA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.820595
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86207
GTEX-Q2AH-0626-SM-48TZJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34313
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867028
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03438
A549_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180088
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate	GTEx Tissue Gene Expression Profiles	1.0	0.827528
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919365
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31686
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44168
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Reticulocyte fraction of red cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6301
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.104799
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sapanisertib_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0228764
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.1486
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35516
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944579
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287702
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44853
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87572
K562_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188278
Anterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889454
Vortioxetine_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0157666
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2631
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42947
Axillary bud meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
L-Eflornithine (monohydrochloride)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0122652
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65145
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953052
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32228
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27139
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34933
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23913
AA-81-IB40_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286276
multiple sclerosis	GWASdb SNP-Disease Associations	1.0	1.00203
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lidocaine (hydrochloride)_SW 900	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.016782
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.940272
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46679
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal external genitalia	GWASdb SNP-Phenotype Associations	1.0	0.267827
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colo-205 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225987
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70499
GTEX-T5JC-1226-SM-4DM7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966808
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_AT9283_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157448
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9561
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.88453
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983549
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88851
DNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14283
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71748
USF2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23017
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29478
GSE242290_3_v_6_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02024
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8607
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23623
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.058153
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879868
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.140995
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926816
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882602
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911138
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00193
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5068
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1579
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	3.66103
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal bone structure	GWASdb SNP-Phenotype Associations	1.0	0.584073
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891962
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
Type I pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66227
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.47377
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
abnormality of radial diaphysis	GWASdb SNP-Phenotype Associations	1.0	0.881236
A549_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012997
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.88139
J-82 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
abnormality of the clavicle	GWASdb SNP-Phenotype Associations	1.0	0.881236
Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.74824
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0352
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00971
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47038
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40363
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77553
Ankyrin repeat-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
Anorexia nervosa	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5588
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01957
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881554
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1435
HMGN3	ENCODE Transcription Factor Targets	1.0	null
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4892
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43808
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23017
A549_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155055
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994821
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25573
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.58341
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24751
HTATSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08915
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13094
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6153
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.331
SHP77	CCLE Cell Line Gene CNV Profiles	1.0	2.24153
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46652
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00317
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37371
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22504
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12571
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCT-116 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46866
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56021
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07678
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59493
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EW8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4988
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0523
A549_Temsirolimus_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157773
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12623
t47d	HPA Cell Line Gene Expression Profiles	-1.0	-1.75533
FBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24202
Balsalazide (sodium hydrate)_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0210075
K562_WP1066_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156629
CC-90-NK44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277164
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92017
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84082
Cul2-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30552
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02587
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15123
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883844
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.940272
sclerosis of hand bone	GWASdb SNP-Phenotype Associations	1.0	0.881236
1536_CFL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.58789
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890237
Almonertinib (hydrochloride)_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0221603
1458_CDT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.773797
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18615
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5333
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861854
abnormality of the humerus	GWASdb SNP-Phenotype Associations	1.0	0.881236
A549_SRT2104_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151826
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cepharanthine_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0180663
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40136
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22834
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
humeral sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
demyelinating disease	GWASdb SNP-Disease Associations	1.0	1.00203
MAFK	ENCODE Transcription Factor Targets	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.22063
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93994
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.12692
Duckembryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.56368
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.409116
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14404
YIPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33739
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03887
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH2141	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51182
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-3664-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal cortical bone morphology	GWASdb SNP-Phenotype Associations	1.0	0.881236
ZNF268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56807
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53926
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0316
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44485
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7607_RUVBL1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.523162
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05452
8085_SLC43A1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.597877
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40757
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Flavopiridol HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226855
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89866
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12571
Oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883139
S-Adenosyl-L-methionine (disulfate tosylate)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0155057
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13259
H2AC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08976
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72245
A549_Ofloxacin_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124951
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.134138
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948308
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890561
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17044
GSE215086_3_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	1.37014
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77443
abnormality of the rib cage	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91607
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5875
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36418
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30922
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20851
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906784
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50894
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.58363
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.70147
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06584
choroidal sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
Adventitious root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10521
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54822
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Curli	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16263
1315_CCNA2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.547935
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.113122
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20665
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59735
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862301
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
K562_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171873
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76162
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21187
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.07278
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tirabrutinib_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0179083
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962389
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	2.34193
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
7566_RRP7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.503334
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15659
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93043
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39151
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18051
5470_NAT10_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.75473
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29892
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887206
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07817
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09245
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19353
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45818
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.3626
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05826
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.867514
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reticulocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7699
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1997
J82	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44314
GTEX-WFG7-0926-SM-4LMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998679
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89866
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84213
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75691
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916011
Lymphocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26383
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6411
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954349
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934874
abnormality of upper limb metaphysis	GWASdb SNP-Phenotype Associations	1.0	0.881236
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833081
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.86517
Mean corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
abnormality of limbs	GWASdb SNP-Phenotype Associations	1.0	0.410695
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.68233
abnormality of the upper arm	GWASdb SNP-Phenotype Associations	1.0	0.486206
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11877
breast	HPA Tissue Protein Expression Profiles	-1.0	-2.30927
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.61377
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TD-69-UA90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210654
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844396
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Interleukin-1-receptor antagonist levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.974817
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07098
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22385
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40072
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
increased density of long bones	GWASdb SNP-Phenotype Associations	1.0	0.881236
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the uvea	GWASdb SNP-Phenotype Associations	1.0	0.296278
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17553
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.62852
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.716
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.940272
hsa-miR-193b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840942
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68685
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-2626-SM-4BRVA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921303
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46364
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17718
Rad51B-Rad51C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20256
vertebral body sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
Retrocerebral complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
Cepharanthine_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0142083
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67852
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50266
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0172
OC-10-FB51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217817
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40363
Sulfisoxazole_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0302309
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02968
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20027
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7151
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954349
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23227
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14975
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40363
Hematocrit	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
DF-37-AV77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20119
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18028
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24038
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Dapagliflozin_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00957621
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07934
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956094
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.606357
PMC9745835-supp_079195.122_Supplemental_Table_1.xlsx-ADAR-KD-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
7251_RFFL_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.620182
prostate disease	GWASdb SNP-Disease Associations	1.0	0.871773
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33177
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03953
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14061
Type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2643
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915436
lm9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871023
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09357
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977702
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09396
GTEX-OHPM-0226-SM-3LK61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64426
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887439
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8499
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AZD1390_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0125515
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930892
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32969
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357321
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.548511
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43558
GTEX-QDVN-1126-SM-48TZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16308
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5516
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.609589
abnormality of the hand	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08174
GSE215086_4_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10424
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221355
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42499
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833994
1747_COG8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.620527
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	1.1865
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0748
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.1709
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9578
BLZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21436
K562_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139707
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12727
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49443
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22035
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12571
GTEX-P4PP-2526-SM-3P61P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875848
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Excessive daytime sleepiness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41931
Epicuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
K562_EED226_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169649
abnormality of the costochondral junction	GWASdb SNP-Phenotype Associations	1.0	0.881236
Lymphocyte percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0703
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1661
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dexmedetomidine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0160638
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6032
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
6548_POLR2G_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.608398
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1036
urethral obstruction	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874316
abnormality of the nephron	GWASdb SNP-Phenotype Associations	1.0	0.486206
Coronary artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.850467
Pexidartinib (hydrochloride)_SW 900	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0119923
Olanzapine_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0215582
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
hsa-miR-4420	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Acn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
Tofacitinib_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0108252
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Torkinib_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0132748
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239542
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03359
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_Aurora A Inhibitor I_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143373
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1117
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01668
Sarcolemma	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
4149_INTS4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.523344
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4386
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8176
K562_Ellagic acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157316
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98647
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.15395
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29776
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.38657
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	1.51944
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941498
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.29624
GTEX-R55G-2426-SM-2TC5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934217
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.621507
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02711
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09544
abnormality of the kidney	GWASdb SNP-Phenotype Associations	1.0	0.306554
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02469
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45928
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83723
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00444
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32514
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28037
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9908
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.11742
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10213
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.01759
Torkinib_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0238633
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45359
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18578
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.44382
H4K20me1_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
9617_URB1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.572599
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92164
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-0.871305
A549_SRT2104_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187583
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19822
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866044
Small_Intestine-intestinal tuft cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.51779
Imiquimod (hydrochloride)_NCI-H596	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0331697
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09648
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.38146
Type III site-specific deoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.269
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27821
EZH2	ENCODE Transcription Factor Targets	1.0	null
abnormality of limb bone	GWASdb SNP-Phenotype Associations	1.0	0.573837
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FHC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44917
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
all	GWASdb SNP-Phenotype Associations	1.0	0.122225
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865346
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83387
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09064
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06748
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15504
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10442
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93398
Leaf bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21811
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.532
MAPKAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06208
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55559
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851912
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07656
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45743
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07158
abnormality of the skull base	GWASdb SNP-Phenotype Associations	1.0	0.881236
Elytron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
Aortic adventitial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.052752
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
diffuse mesangial sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33453
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	1.0	1.32854
abnormality of the male genitalia	GWASdb SNP-Phenotype Associations	1.0	0.244301
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of facial skeleton	GWASdb SNP-Phenotype Associations	1.0	0.403971
GD-70-NJ06_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295956
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98872
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839907
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.66572
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01876
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06902
Red cell distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.2
Folic acid_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0351981
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.831435
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.977348
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4026
abnormality of finger	GWASdb SNP-Phenotype Associations	1.0	0.881236
M059K	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41183
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95494
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60507
VB-89-RG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227336
hsa-miR-4474-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47335
H4K20me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21304
K562_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017557
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1436
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.509
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60462
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.552621
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Busulfan_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0125208
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
EWS502	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52066
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.992067
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	1.63615
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4198
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844269
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01342
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18622
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40994
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906601
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.00425
A549_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137419
abnormality of digit	GWASdb SNP-Phenotype Associations	1.0	0.881236
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98872
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870054
patchy osteosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35431
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22834
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.906205
Lumateperone (tosylate)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0196577
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00764
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44993
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.35229
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15188
hsa-miR-4646-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40929
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CP21R7_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0228504
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39884
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05598
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2523
Urinary bladder transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89866
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08482
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.4401
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882931
10571_ZNF705D_ENST00000400085.3	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.559834
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16782
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.931043
Adagrasib_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.044505
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38017
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sclerotic forearm bones	GWASdb SNP-Phenotype Associations	1.0	0.881236
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45657
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0392
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18037
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41387
Bimatoprost_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0113104
Hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.10969
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42581
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976729
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27899
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01501
CTCF	ENCODE Transcription Factor Targets	1.0	null
Sinomenine_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.027016
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.928778
hsa-miR-193a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899168
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
abnormality of the upper urinary tract	GWASdb SNP-Phenotype Associations	1.0	0.306554
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07698
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7826
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94219
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855561
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70781
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of upper limb bone	GWASdb SNP-Phenotype Associations	1.0	0.881236
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.038185
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.75
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7286
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75517
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73645
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909973
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01183
Atazanavir (sulfate)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0177681
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2836
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.41958
TCC-SUP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24411
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12947
Plume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929741
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.29721
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07731
KYSE30	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32756
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1179
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65688
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52974
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54305
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46345
sclerosis of metaphyses of the upper limbs	GWASdb SNP-Phenotype Associations	1.0	0.881236
Benproperine (phosphate)_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0170626
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57223
mesangial abnormality	GWASdb SNP-Phenotype Associations	1.0	0.881236
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7843
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.965757
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857865
cortical sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15871
craniofacial osteosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.881236
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40136
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17474
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830343
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33066