association	dataset	threshold value	standardized value
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.381
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54579
Legionellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46493
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20905
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Muckle-Wells syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
ACHN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970653
NCIH747	DepMap CRISPR Gene Dependency	1.0	2.06599
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87314
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30099
LEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65132
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878591
Ripoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.353
OE33	CCLE Cell Line Gene CNV Profiles	1.0	2.20504
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
AXIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.39929
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15884
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01659
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IX-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980081
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50376
Hematological parameters	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
KYAE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16843
PMC11630641-mmc8.xlsx-Human_1000cell_NOT_identified-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29395
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.654
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.990931
HCC1954	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92231
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91035
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902636
ADCYAP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16251
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.5418
IM95	DepMap CRISPR Gene Dependency	1.0	2.88902
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31371
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63503
MYC	ENCODE Transcription Factor Targets	1.0	null
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.41658
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB3A_Mutation - D77G point mutation_GDS2483_698_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48159
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NADPH oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.559
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23932
CTNNB1-24651522-LGR5+ INTESTINAL STEM CELL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.269
hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712549
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18463
Childhood Asthma	DisGeNET Gene-Disease Associations	1.0	null
SUM190PT	DepMap CRISPR Gene Dependency	1.0	2.70396
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
Tectum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
SRSF7_02_89	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.45943
Middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73803
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42569
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27346
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28067
abnormality of the integument	GWASdb SNP-Phenotype Associations	1.0	0.084965
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.5374
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
channel activity	GO Molecular Function Annotations 2023	1.0	null
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.689
HCC1428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CINCA Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06433
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08702
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28079
GSE112202_5_v_2_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
continent	GeneRIF Biological Term Annotations	1.0	null
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44956
abdominal symptom	GWASdb SNP-Phenotype Associations	1.0	0.295011
Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.4104
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.91215
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902636
Extracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.071
PMC7886351-elife-65905-supp3.xlsx-Supplementary_file_3a-MYB_IP-MS_protein_lists_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.943
Superior colliculus, motor related, intermediate gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10873
Neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.313
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.004
Rectum adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
HEPA 1-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00523
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.991975
gastric epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.761155
three	GeneRIF Biological Term Annotations	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053659
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07904
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03361
perinuclear region of cytoplasm	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-548h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.051166
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.830848
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.087
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.627081
dermatitis	GWASdb SNP-Disease Associations	1.0	0.371529
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060509
NCIH1693	DepMap CRISPR Gene Dependency	1.0	2.83779
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30401
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70367
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0546
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Cleavage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Neutrophil extracellular trap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.05
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ureteral obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
THP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38033
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59619
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40915
corneal opacity	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57151
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
ZNF564	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84123
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33109
abnormal hair growth	MGI Mouse Phenotype Associations 2023	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31488
Adrenal cortex cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.885
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905372
CHD1	ENCODE Transcription Factor Targets	1.0	null
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
LETMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93015
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01092
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02647
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27113
UW228	DepMap CRISPR Gene Dependency	1.0	2.52676
NCIH2030	DepMap CRISPR Gene Dependency	1.0	2.09869
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52091
White Blood Cell Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01506
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882042
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.445
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33661
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.62
present	GeneRIF Biological Term Annotations	1.0	null
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19759
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911521
Th2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25731
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCW-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306083
Dehydrodolichyl diphosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
ESCRT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.143
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.922619
PPARG	ChEA Transcription Factor Targets	1.0	null
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37095
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6329
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39108
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25096
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040838
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
med24	GeneRIF Biological Term Annotations	1.0	null
HSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17046
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	1.01845
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12208
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25067
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.167
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.8271
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81252
CYTH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25375
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98573
linked	GeneRIF Biological Term Annotations	1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49886
decreased erythrocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855306
Cervicovaginal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41461
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58592
MAP1S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64147
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5492
mantle zone of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48296
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38728
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852587
sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.736794
lmo1	GeneRIF Biological Term Annotations	1.0	null
skin lesions	MGI Mouse Phenotype Associations 2023	1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00759
Brain Lower Grade Glioma_LGG_TCGA-FG-6691-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22071
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	2.00616
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5998130-41467_2018_4619_MOESM7_ESM.xlsx-specificity_NCOA3-Gene_Name_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4769
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	352.829
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902696
NOS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69046
GTEX-OXRN-0226-SM-2I5EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971141
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.6819
NLRP3 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.012
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55045
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
imply	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875334
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Phosphatidylinositol 3-kinase complex, class III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.257358
Pancreatic ductal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0238
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
early	GeneRIF Biological Term Annotations	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91158
Rectum adenocarcinoma_READ_TCGA-AH-6544-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3176
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81845
SMAD5_02_48	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
phosphatidylinositol phosphate binding	GO Molecular Function Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75524
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11781
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.589
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEC8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074102
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	516.739
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33661
Skin epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14279
absent sebaceous gland	MGI Mouse Phenotype Associations 2023	1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04207
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48184
oncogenomic	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09163
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57583
Vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.267
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40659
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26128
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29256
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62874
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56753
A375SKINCJ1	DepMap CRISPR Gene Dependency	1.0	2.96414
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	1.68078
gsdma	GeneRIF Biological Term Annotations	1.0	null
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
QPCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46157
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E12	MotifMap Predicted Transcription Factor Targets	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12176
OV7	DepMap CRISPR Gene Dependency	1.0	2.00318
KYSE410	CCLE Cell Line Gene CNV Profiles	1.0	2.09817
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
Lysosomal lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
enlarged lymph nodes	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WHWD-0826-SM-3LK6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85683
WWC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24497
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985817
Mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.718
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35436
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.108
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00843
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91035
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.922619
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21624
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00707
RUNX1	ChEA Transcription Factor Targets	1.0	null
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3878
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protoxylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.201648
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10873
FHIP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46976
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43772
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39127
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.10265
phosphatidylinositol-4,5-bisphosphate binding	GO Molecular Function Annotations 2023	1.0	null
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11705
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
Hypersensitivity reaction type IV disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
RERF-LC-SQ1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	GeneRIF Biological Term Annotations	1.0	null
Eczema	DisGeNET Gene-Disease Associations	1.0	null
UBB_KO_GDS3906_491_mouse_Testis - 7 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
gsdm	GeneRIF Biological Term Annotations	1.0	null
Glycine cleavage complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.819
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833343
PGBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36879
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24841
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.528719
Colonic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
Ragulator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.542
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84791
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855933
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03957
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.461465
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38325
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.03569
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60802
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91035
AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61661
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62875
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.839205
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04027
Respiratory allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52489
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GD-82-CS38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24447
Shigellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29903
bronchial disease	GWASdb SNP-Disease Associations	1.0	1.70155
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46493
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939677
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
OE33	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.4974
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
Mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.183
Protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
phosphatidylinositol bisphosphate binding	GO Molecular Function Annotations 2023	1.0	null
upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.090482
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64582
Asthma	GWAS Catalog SNP-Phenotype Associations	1.0	0.463473
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.254536
GTEX-XV7Q-2626-SM-4BRVA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883944
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54579
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22741
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.925249
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.8441
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heart conduction disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
epithelium	GeneRIF Biological Term Annotations	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5007654-srep32566-s2.xls-DISEASE_GENE-POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28869
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832065
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	524.555
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
lung disease	GWASdb SNP-Disease Associations	1.0	0.41658
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46293
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tm95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50496
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06893
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.68658
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39507
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of InsCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50293
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89321
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149958
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55072
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06883
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7372-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
guanyl-nucleotide exchange factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.54
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.061708
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29042
Interferon regulatory factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.361
TERALPHA	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943244
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39044
XRCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31217
Glutathione synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.203604
hsa-miR-548a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41416
OVCA420	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52221
Nose disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8052
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86532
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94911
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31773
Acute leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.269
FOS	ENCODE Transcription Factor Targets	1.0	null
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17346
GTEX-QCQG-1526-SM-48U25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867236
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97505
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2096
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
hemolytic anemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.5306
PTBP1_02_120	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.24793
TAF15_02_163	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.52356
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13758
Tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26006
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44068
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.446
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45028
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.841444
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913433
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43327
B16-F10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.561725
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47524
decreased alkaline phosphatase activity	MGI Mouse Phenotype Associations 2023	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.53555
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883627
SREBF1	ChEA Transcription Factor Targets	1.0	null
Extracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.204
AKT1_knockout_214_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.657
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94046
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08009
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34068
Stomach	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34083
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10341
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12123
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60043
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.561725
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994565
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248361
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059771
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64226
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08435
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01582
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94826
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900225
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20023
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.5273
programmed cell death	GO Biological Process Annotations 2015	1.0	null
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.069
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87698
KYAE1	DepMap CRISPR Gene Dependency	1.0	2.34716
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39964
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98689
MIDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76037
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
KLF4_01_339	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.11581
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8383365__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Acute lymphoblastic leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.269
Mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.225
Liver enzyme levels (alkaline phosphatase)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.90458
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
Sarcoma_SARC_TCGA-DX-A3LY-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thin hair shaft	MGI Mouse Phenotype Associations 2023	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.914
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02678
fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.009
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.02
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.889921
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7164
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.971984
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
ARPE-19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
Respiratory Hypersensitivity	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05449
rectum_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.887668
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4787-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.18668
COQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56056
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.2105
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35035
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997206
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rnf2_21051595_92dot1_lof_human_gpl10558_gse24896	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.546315
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.867771
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2258
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.44464
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
mpkCCD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042372
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.882793
Extrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
hsa-miR-3162-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47449
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
dorsal terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19452
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28221
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.998332
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56923
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2053
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EZH2	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01259
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60429
Macrophage cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
RPL26L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20401
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
hsa-miR-4496	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79447
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08836
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3425-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7901903__F1	PFOCR Pathway Figure Associations 2023	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65792
Lymphopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2611
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21625
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26128
Glandular stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
Bcl-2 family protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.946
LRATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82559
HCA1	DepMap CRISPR Gene Dependency	1.0	2.30902
STING complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.052
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.109
Bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.955
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46759
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54321
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
hsa-miR-587	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30396
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7115
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33517
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9145
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.839211
CENPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20034
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960964
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53346
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039982
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12757
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
hsa-miR-760	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12663
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2273
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88882
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91035
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
normocytic anemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.5306
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.782
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86061
LRRC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13017
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	2.365
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8256
Outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.02
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16981
Aortic intima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.016
496100530_FWM_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41277
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36766
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81631
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64138
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88456
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.129
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06754
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70456
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939272
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9709
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.97
prostate_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MITF_02_85	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
RSRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20986
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.869415
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950013
Perturb_15173_KO_PTPN14_SRP167101	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.57889
PMC11604901-13555_2024_1298_MOESM1_ESM.pdf-23-SP2_SP2	Rummagene Transcription Factor Associations 2026	1.0	null
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61759
Histiocytic lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	1.87782
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.05531
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0918
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825071
pretectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07646
Leukocyte Count	dbGAP Gene-Trait Associations	1.0	1.0562
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
Rif1_KD_GDS4943_243_mouse_F1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Tertiary granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
FN3KRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5333
ESCRT III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.999
Sarcoma_SARC_TCGA-DX-A3U6-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7623
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5432-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15676
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
RMG-I	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1343
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vitiligo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37486
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66232
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27874
thick skin	MGI Mouse Phenotype Associations 2023	1.0	null
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65792
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.653
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27874
HK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7413-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833343
Phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.189
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51232
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40919
UBALD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87046
USP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32414
apoptosis	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20703
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.049
HCC1143	DepMap CRISPR Gene Dependency	1.0	2.92884
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62455
lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.561725
abnormal hair cycle	MGI Mouse Phenotype Associations 2023	1.0	null
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64438
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.28287
interleukin-1 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.918
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63851
asthma	GWASdb SNP-Disease Associations	1.0	1.70155
Rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14693
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	168.525
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126453
interleukin-6 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18833
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15769
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6
wide pore channel activity	GO Molecular Function Annotations 2023	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8375
Bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06869
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04421
External carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07044
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855933
KMCH1	DepMap CRISPR Gene Dependency	1.0	2.25779
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.717
POLR2J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65631
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52205
PMC8127234-12885_2021_8319_MOESM2_ESM.docx-0-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12415
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21293
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26978
DCAF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75728
FFAR4_KO_GDS4811_507_mouse_adipose	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-548ak	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.407
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43522
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11352
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10563
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24363
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.1338
decreased hematocrit	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_8748_OE_SRC_SRP131095	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1366
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
PRELID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08686
Gastric adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	284.447
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64759
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16521
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredProteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
susceptibility	GeneRIF Biological Term Annotations	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
asthma	GWASdb SNP-Phenotype Associations	1.0	1.57346
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17561
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12538
Alveolar macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.536
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55748
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54209
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.022
LY6E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96431
vitamin c_mus musculus_gpl6246_gse19378	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.63792
cellular process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7521
Phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58339
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055226
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01399
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19714
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23165
ENO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5281
atopic dermatitis	GWASdb SNP-Disease Associations	1.0	0.67359
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96708
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78572
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
Renal proximal tubule epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
ZNF594	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3464
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal corneal epithelium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	1.82085
skin	GTEx Tissue Gene Expression Profiles	1.0	2.18987
Cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.986
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848883
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9541
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9746897__F2	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20943
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44206
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07912
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.61496
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
GTEX-WVLH-0226-SM-3MJG6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923243
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08448
Nasal cavity disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65824
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT3_KO_GDS4817_417_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39118
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
GDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86365
Pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67732
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44172
mcf-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260945
Cardiac microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
Familial Mediterranean fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.038
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3056
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28595
SKNMM	DepMap CRISPR Gene Dependency	1.0	2.65695
Keratinocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4167-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.884009
MG63	DepMap CRISPR Gene Dependency	1.0	2.65487
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87272
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.175
Adrenal cortex disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18956
HUO9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PSMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11357
TCMK-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61584
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28513
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
Lymphocyte percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
spinal cord disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.382966
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.14424
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16104
decreased hematocrit	MGI Mouse Phenotype Associations 2023	1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224645
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12818
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0549
SPI1	ChEA Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.937044
SH3D21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00786
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39953
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05481
investigated	GeneRIF Biological Term Annotations	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.861664
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Myosin III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4266	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Nasopharyngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4445
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39468
RAB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84957
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9324
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85669
mitochondria-associated endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.5
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21089
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57265
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peritoneal macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.561725
increased mean corpuscular hemoglobin	MGI Mouse Phenotype Associations 2023	1.0	null
IRF6_KO_GDS2359_126_mouse_skin E17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
locus	GeneRIF Biological Term Annotations	1.0	null
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959379
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040276
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76225
PMC8602451-41467_2021_26807_MOESM8_ESM.xlsx-SALL1_SUMO-ID-Gene_name_SALL1	Rummagene Transcription Factor Associations 2026	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.44425
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16028
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-938	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069369
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31004
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7362
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37486
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859117
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.43288
EZH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21987
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZFX_KD_GSE43021_130_human_NOMO1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.5699
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12663
RAW-264.7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
Cardiomyocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26128
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.865
Gingival fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63748
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
increased mean corpuscular hemoglobin concentration	IMPC Knockout Mouse Phenotypes	1.0	null
REEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88365
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77517
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
subpretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3584
SCD_KO_GSE24243_46_mouse_Skin (8-9 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09604
H9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB3A_KO_GDS2482_705_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.195
Epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.16
Autolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
all	GWASdb SNP-Phenotype Associations	1.0	0.050842
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.713
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.031
phosphatidylinositol bisphosphate binding	GO Molecular Function Annotations 2025	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.133
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73282
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81585
MXD3_02_83	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.08746
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.6786
atopic dermatitis	GWASdb SNP-Phenotype Associations	1.0	0.577224
ZNF461	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29604
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366754
GTEX-W5X1-1426-SM-3GIKH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872305
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24923
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46454
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267102
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2823
CALU-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908673
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.194
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
Macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.561
PMC11867302-mmc4.xlsx-Table_S5-Table_S5_Single-cell_transcriptome_differential_gene_analysis_DEG_results_for_all_of_our_potential_causal_genes_analyzed_by_MR_and_colocalization_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_8_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36328
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02026
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
alopecia	MGI Mouse Phenotype Associations 2023	1.0	null
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29339
Primary biliary cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11003700-pbio.3002240.s011.xlsx-MYCN-IMR32_RawData-Unnamed_2_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48296
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.92546
Esophageal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
Peptidase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08329
Nasopharynx carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OE33	DepMap CRISPR Gene Dependency	1.0	3.66777
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47S-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone deterioration disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.114
Mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.435
SETDB1	ChEA Transcription Factor Targets	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.025
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	2.65137
PMC12405659-CTM2-15-e70437-s001.xlsx-Supplementary_Table_5-BioGrid-interaction_protein_with_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33755
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58543
IgE immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.416
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12409
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950506
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16679
Fat-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	7.38266
Synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
Mitochondrial envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.187
GSE195559_3_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81755
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.561725
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.5148
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.871234
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.08659
tp92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80614
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.57479
Hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52109
abnormal coat appearance	MGI Mouse Phenotype Associations 2023	1.0	null
MEIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2063
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908673
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.757
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02124
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07869
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.720865
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67604
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.005
Bone marrow-derived macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.048
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.025
intermediate stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52221
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07016
PMC9281180__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.503824
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
Hypersensitivity, Immediate	HuGE Navigator Gene-Phenotype Associations	1.0	null
Esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.456
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51301
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
KMRC3	DepMap CRISPR Gene Dependency	1.0	2.78815
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09194
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072296
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43445
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69003
Mesothelioma_MESO_TCGA-LK-A4O2-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
TMEM39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43601
Apoptotic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.039
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881429
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2309
myc_00000000_e13dot5_heart_lof_mouse_gpl4865_gse7162	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.46605
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950506
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
hyperkeratosis	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73019
NCCIT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.24789
EW16	DepMap CRISPR Gene Dependency	1.0	2.83299
Autosomal recessive nonsyndromic deafness 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.924
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18313
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5143
OS-RC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41067
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860274
FOXP1_01_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.4198
CPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10875
increased susceptibility to bacterial infection	MGI Mouse Phenotype Associations 2023	1.0	null
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81174
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58075
Periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
SK-GT-2	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15321
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
EVSAT	DepMap CRISPR Gene Dependency	1.0	3.63767
C666-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.146457
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
abnormal hair cuticle	MGI Mouse Phenotype Associations 2023	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.64645
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96769
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H4C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4295
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38184
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53428
Mitochondrial chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.016
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42847
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.776
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63327
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19326
MB-49 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
Agranular insular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06707
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
Liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07555
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97383
hsa-miR-4727-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Gastric epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15255
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20285
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900536
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04359
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.886697
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06366
KYSE410	DepMap CRISPR Gene Dependency	1.0	3.11548
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.214
acanthosis	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H1693	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839588
PIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75997
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12272
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DENR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43861
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
5-lipoxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997206
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01453
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal hair cycle anagen phase	MGI Mouse Phenotype Associations 2023	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02563
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845294
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
tgfbeta	GeneRIF Biological Term Annotations	1.0	null
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51573
DECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39099
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26128
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STRA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8907
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
asthma	GeneRIF Biological Term Annotations	1.0	null
PSMB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07909
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56835
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64846
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1912
RBM25_02_119	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.58496
Ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.405
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.334
mantle zone of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50211
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.2703
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5970-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
chr17_39969978_A_G_b38	GTEx eQTL 2025	1.0	1.16123
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4173
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11471
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83439
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.54025
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08448
Systemic sclerosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9162454__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	83.431
Bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.131
Lymphoid leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.269
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02678
PMC10158025-ijbsv19p2081s6.xlsx-SupTable5-ZBTB20_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5699
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75579
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51016
Gamma delta T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40286
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28919
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.960863
NRK-52E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843185
death	GO Biological Process Annotations 2015	1.0	null
obstructive lung disease	GWASdb SNP-Disease Associations	1.0	0.68314
Hay Fever	DisGeNET Gene-Disease Associations	1.0	null
ELP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30323
PMC12515692-MOL2-19-2882-s005.xlsx-Proteome_AKT1_AKT2_KD_vs_SCR-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06172
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17436
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65492
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6331
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.56323
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52162
wide pore channel activity	GO Molecular Function Annotations 2025	1.0	null
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredPeptides-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0546
PKBalpha_KO_GDS1784_194_mouse_Embryonic fibroblasts (MEFs) - 2h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11037
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48025
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.926105
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165874
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54056
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887088
enlarged spleen	MGI Mouse Phenotype Associations 2023	1.0	null
ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
hsa-miR-3147	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.443
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12953
Colon adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Retinal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
Monocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.807
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81051
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2622
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91965
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07898
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041985
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17507
SAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.113
phosphatidylinositol phosphate binding	GO Molecular Function Annotations 2023	1.0	null
Intervertebral disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06498
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
TP63	ChEA Transcription Factor Targets	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07646
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13769
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28146
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53703
Myocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33554
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14428
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.083
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94288
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79558
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.174
hsa-miR-770-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
Melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.754
18614019-TableS4d	GeneSigDB Published Gene Signatures	1.0	null
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2709
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12663
GMPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46566
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18676
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
Mitochondrial permeability transition pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.453
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061065
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29975
apoptotic process	GO Biological Process Annotations 2015	1.0	null
Late endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.523
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.925249
HBE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25557
F8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52433
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
PMC10898041-41065_2024_311_MOESM1_ESM.docx-0-FOXL2_FOXL2	Rummagene Transcription Factor Associations 2026	1.0	null
RAMOS-2G6-4C10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal hair follicle bulge morphology	MGI Mouse Phenotype Associations 2023	1.0	null
recombination	GeneRIF Biological Term Annotations	1.0	null
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.0833
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11327744-CCHTS-27-1161_SD1.pdf-1-IRF2_IRF2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33839
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70476
Primary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163111
ESO51	DepMap CRISPR Gene Dependency	1.0	2.13963
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14211
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4972-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.979619
Hair follicle bulge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95055
Membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.866
Mitochondrial outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.843
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94889
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36287
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.635
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Calpain complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
NFYA_01_355	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63659
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Midbrain, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27314
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.257005
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7631
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51908
chromosome	GeneRIF Biological Term Annotations	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	1.0	0.886958
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
HaCaT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
Serine protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.23
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.988
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21778
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.977
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01092
long hair	MGI Mouse Phenotype Associations 2023	1.0	null
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
RIGI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16639
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11031
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.283
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.971
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29837
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
UTP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32623
enlarged thymus	MGI Mouse Phenotype Associations 2023	1.0	null
Hemophagocytic lymphohistiocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.668
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23412
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36738
hsa-miR-145	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC25A24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49448
Esophageal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.922619
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28665
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37192
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82816
Asthma and hay fever	GWAS Catalog SNP-Phenotype Associations	1.0	0.552116
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06879
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01892
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3062
Np	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
AML-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48802
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.830259
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
abnormal skin morphology	MGI Mouse Phenotype Associations 2023	1.0	null
affecting	GeneRIF Biological Term Annotations	1.0	null
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12663
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Collecting duct cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
GSE127916_1_v_4_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Organelle envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
Glomerular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940193
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2639
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78903
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.42321
leukocyte count	GAD Gene-Disease Associations	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.70785
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05111
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84769
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86655
gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.867263
CEBPB	ChEA Transcription Factor Targets	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22066
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5511
microphthalmia	MGI Mouse Phenotype Associations 2023	1.0	null
Esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.604
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83932
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
immune	GeneRIF Biological Term Annotations	1.0	null
CHP-126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978168
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48467
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08266
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05957
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37982
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autophagosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.03
interleukin-18 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.329
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	1.54733
hsa-miR-651	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Pneumoconiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03845
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0568
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10553
Helper T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167243
Autophagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.883
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.138573
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13776
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188626
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5709
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096209
White blood cell count	GWAS Catalog SNP-Phenotype Associations	1.0	0.696558
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04995
dermatitis	MGI Mouse Phenotype Associations 2023	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.061765
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38676
regulatory	GeneRIF Biological Term Annotations	1.0	null
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60827
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IPAF inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33135
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76977
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.109
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
MIXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34467
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OSBPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5914
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.394284
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054994
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00212
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.473
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970139
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53884
Liver cirrhosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IC-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C11orf71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18014
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53765
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
european	GeneRIF Biological Term Annotations	1.0	null
FBXO48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55953
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.806947
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877112
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.999
phosphatidylinositol-4,5-bisphosphate binding	GO Molecular Function Annotations 2025	1.0	null
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16842
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08856
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43612
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17406
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11865
hsa-miR-4291	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58008
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36786
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09613
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53162
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.511112
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.0773
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
progressive hair loss	MGI Mouse Phenotype Associations 2023	1.0	null
Gut mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.9415
PMC12335101-12575_2025_286_MOESM1_ESM.pdf-1-IRF2_IRF2	Rummagene Transcription Factor Associations 2026	1.0	null
ADNP_Deficiency - NULL MUTATION_GDS2540_692_mouse_E9 embryos - Homozygous mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.469
Organelle outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.837
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54056
GTEX-PWOO-2226-SM-2S1P1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839124
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28332
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3038
Nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60441
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36156
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44779
ZC3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50421
HT-29-MTX cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
OACP4C	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32407
phenotypes	GeneRIF Biological Term Annotations	1.0	null
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07904
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.469
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516497
Natural killer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.147
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83948
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59434
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Y-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Apoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.974
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HZ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.284
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00107
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37192
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56273
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19951
M14 melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A819-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF5	ChEA Transcription Factor Targets	1.0	null
Limited cutaneous systemic scleroderma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052859
PAQR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03542
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12663
CD79B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90974
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881429
Nucleus pulposus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64599
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	173.675
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.072
JTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84568
Perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25233
Autoimmune lymphoproliferative syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
artery disease	GWASdb SNP-Disease Associations	1.0	0.249866
SNX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76945
hsa-miR-2681	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59256
Lung epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
Esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
TGM2_KD_GSE23702_715_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.7591
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15116
Parkin-FBXW7-Cul1 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
NTPCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12607
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07889
RRP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72879
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18945
Rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
PMC11518656-ADHM-13-0-s002.pdf-40-BAZ2B_BAZ2B	Rummagene Transcription Factor Associations 2026	1.0	null
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18384
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38688
GATA1	ENCODE Transcription Factor Targets	1.0	null
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.841
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4176-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
TP53	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.232
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900536
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.88816
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51545
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22318
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31882
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H9c2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
CFPAC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
midbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09255
Asthma or allergic disease (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.63979
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17965
Cardiac muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
level	GeneRIF Biological Term Annotations	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7971
secretion	GeneRIF Biological Term Annotations	1.0	null
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRA_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876354
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91011
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31981
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01096
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	2.59705
gk1.5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
T-47 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.0787
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
SNU899	CCLE Cell Line Gene CNV Profiles	1.0	1.40236
around	GeneRIF Biological Term Annotations	1.0	null
rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.203604
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
PMC12354852-41467_2025_62818_MOESM3_ESM.xlsx-Sup_Data_10-Differentially_expressed_genes_in_TAF6L_KD_vs_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
Atrial fibrillation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27982
PIH1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81814
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0713
MARVELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50759
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4663
decreased hair follicle number	MGI Mouse Phenotype Associations 2023	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	84.1842
hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23227
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05442
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.2228
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27314
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sparse hair	MGI Mouse Phenotype Associations 2023	1.0	null
abnormal hair follicle development	MGI Mouse Phenotype Associations 2023	1.0	null
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2956
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89275
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26269
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6349
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.311
SK-OV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pyroptosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.065
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17983
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.259477
Sarcoma_SARC_TCGA-DX-A23V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929111
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19596
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99476
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21144
Glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05479
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.136734
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35754
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.350084
HP1BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26228
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02641
ventral part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10873
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18423
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
Calu-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18894
Lung adenocarcinoma_LUAD_TCGA-99-8032-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72501
mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213471
NFYA_02_76	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.62936
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08737
Inflammatory bowel disease 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BL2465 (NCOA7)	NURSA Protein Complexes	1.0	null
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09558
PRRC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43409
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04723
hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.582384
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02183
Lung adenocarcinoma_LUAD_TCGA-55-8619-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bronchial epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52072
ATF3	ChEA Transcription Factor Targets	1.0	null
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61054
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.8
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
Autoimmune lymphoproliferative syndrome type 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6392
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	1.42635
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42119
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.875484
ovary	HPA Tissue Gene Expression Profiles	-1.0	-0.933447
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7651-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
inflammatory response	GO Biological Process Annotations 2025	1.0	null
MYB	JASPAR Predicted Transcription Factor Targets	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116609
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259929
NPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48386
leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.368998
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76513
MAFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34912
PDCD6IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36578
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63785
WDR81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3039
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866669
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042763
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66327
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15565
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	1.59887
Familial cold autoinflammatory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
abnormal skin adnexa morphology	MGI Mouse Phenotype Associations 2023	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anion binding	GO Molecular Function Annotations 2025	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22194
Uterine cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
Atg1/ULK1 kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
FOXP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90057
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13632
UGCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82489
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10813
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07957
GSE64513_0_v_1_foxd3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pyroptosis	GO Biological Process Annotations 2023	1.0	null
delayed hair regrowth	MGI Mouse Phenotype Associations 2023	1.0	null
AU565	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
HGC-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
Juvenile rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1506
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.02116
NOTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27484
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03538
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38603
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Chromophobe renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Lung squamous cell carcinoma_LUSC_TCGA-46-3769-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8138
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18945
rs7216389	GeneRIF Biological Term Annotations	1.0	null
Allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
STOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08361
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055695
GSE131903_0_v_2_abca12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052885
PMC9306206-12915_2022_1367_MOESM6_ESM.xlsx-Table_S7_-_JIP-Gene_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
NLRP1 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.361
layer 5 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54453
GTEX-S4Q7-1626-SM-3K2AE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98209
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07079
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50585
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7665
MATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7278
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55131
decreased erythrocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Azurophil granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
CYRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49589
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49339
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83844
SRY	ChEA Transcription Factor Targets	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0345
Microglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.821
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NLRP6 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.615
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09823
increased mean corpuscular hemoglobin concentration	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCT-116 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
TRIM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35081
Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64351
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.517678
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.316
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11025
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99833
intracellular part	GO Cellular Component Annotations 2015	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84492
TTC9C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38091
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18365
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
tcell	GeneRIF Biological Term Annotations	1.0	null
WHSC1_02_66	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.12928
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.469
Disseminated intravascular coagulation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
Myeloid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
Periodontitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27948
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27314
Colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.641
ZW10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42078
Gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52785
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1503
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46334
17875932-TableS4	GeneSigDB Published Gene Signatures	1.0	null
DANG	DepMap CRISPR Gene Dependency	1.0	2.51215
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26849
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.867448
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
NEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24526
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56921
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0795
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71825
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37225
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.52646
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
Rheumatoid arthritis disease specific fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
Mitochondrial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.975
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2096
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20626
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.088
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8385
Ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.423
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	163.108
MITF	ChEA Transcription Factor Targets	1.0	null
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859336
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55627
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27994
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1693	CCLE Cell Line Gene CNV Profiles	1.0	1.739
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.255946
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24448
KAT2B_02_184	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65208
count	GeneRIF Biological Term Annotations	1.0	null
Mitochondrial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.017
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Colonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33127
BUB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17152
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77033
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50307
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
Bacterial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.100285
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052799
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855933
hsa-miR-4712-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Clear cell renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179447
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92439
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.0985
NOP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5078
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29284
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20185
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59989
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
UACC-893	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
big ears	MGI Mouse Phenotype Associations 2023	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06366
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27147
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23793
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3093
Lung adenocarcinoma_LUAD_TCGA-J2-A4AG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type I interferon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39368
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08064
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89663
ES-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02226
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12538
RBM15_02_87	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.20945
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.357
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
Vacuolar lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
GTEX-WRHK-0826-SM-3MJFG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917387
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98105
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16634
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8717
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36173
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25015
MEWO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.997
GTEX-XUZC-1126-SM-4BOPZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951332
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33434
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68834
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053012
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60463
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22663
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43205
Adrenal gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Upper respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
KO52	COSMIC Cell Line Gene Mutation Profiles	1.0	null
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18038
Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.352
RAB3GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58578
defense response to bacterium	GO Biological Process Annotations 2025	1.0	null
RHEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06381
runx3	GeneRIF Biological Term Annotations	1.0	null
glutamate-cysteine ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
Cervical cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30982
Pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.973
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5109
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924702
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
RNPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.587
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60872
gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266757
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39988
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35954
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	538.532
Superior colliculus, motor related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19962
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04463
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.6159
AIM2 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.497
immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.5306
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.859
SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997206
cas1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5335
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	3.74867
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46562
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.113
EDS1 disease-resistance complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90595
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45125
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6931
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.34694
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36479
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.0469
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844208
ZNF608	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99953
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31743
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00423
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833343
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	0.922619
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26411
MM383	DepMap CRISPR Gene Dependency	1.0	2.06865
asthma	GAD Gene-Disease Associations	1.0	null
FNDC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83312
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87157
LUBAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
cell death	GO Biological Process Annotations 2015	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.7595
ficolin-1-rich granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
ENSG00000286190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0636
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94831
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46907
Spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.189
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092035
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07719
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0984
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58716
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
Cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.211
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27647
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
myocardial infarction	GWASdb SNP-Disease Associations	1.0	1.68078
Alveolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
4T1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.922619
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.21978
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3382-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
white	GeneRIF Biological Term Annotations	1.0	null
ACADS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72949
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04237
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.927
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7021
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.016
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19242
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29796
hsa-miR-4284	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91041
ppp1r1bstard3tcappnmtperld1erbb2c17orf37grb7	GeneRIF Biological Term Annotations	1.0	null
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32755
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826845
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08977
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15537
HSPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86257
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.969
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17553
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.186
Ulcerative colitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.269
RAB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81549
Gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.45
Goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Host cellular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87919
TCEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50101
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.2849
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92539
perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.922619
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20285
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.561725
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24363
C32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.932
PMC8482521-mmc13.xlsx-Phosphosites_48vhr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58068
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.005
D283MED	DepMap CRISPR Gene Dependency	1.0	2.23065
Bronchial hyperresponsiveness in asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.95229
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
Thrombophilia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08074
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04015
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13246
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2008
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44249
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL4037 (CORO1A)	NURSA Protein Complexes	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60872
J-774A.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46709
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24502
Acute Myeloid Leukemia_LAML_TCGA-AB-2867-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859126
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86605
CDC14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58124
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54056
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34091
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38247
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14436
immunologic hypersensitivity	GWASdb SNP-Phenotype Associations	1.0	0.4279
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.181
CEBPZ_02_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1563	CCLE Cell Line Gene CNV Profiles	1.0	1.55453
SUMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44105
Endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.099
hotspot	GeneRIF Biological Term Annotations	1.0	null
Intestinal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.877
sw837	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
EPB41L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97883
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.852006
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05144
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8536
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98147
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Eiii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
BCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55952
mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.914
PMC9334849-Table_3.xlsx-subcutaneous_adipose_tissue-D1_VS_D9_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21594
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35022
Cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.836
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65792
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PQ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94783
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.8378
SPNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5917
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87032
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
HMGN3_02_45	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.47573
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
family	GeneRIF Biological Term Annotations	1.0	null
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28644
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rs7212938	GeneRIF Biological Term Annotations	1.0	null
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07347
NOMO1	DepMap CRISPR Gene Dependency	1.0	2.0906
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
Lung epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.451
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46531
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12653
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471927
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bronchial disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.561725
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27147
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_proteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33147
CCDC184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3152
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13804
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.788
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2451
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45749
reticular formation of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84765
Degenerative disc disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53387
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.6761
increased susceptibility to bacterial infection induced morbidity/mortality	MGI Mouse Phenotype Associations 2023	1.0	null
PRKRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47547
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8131-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.359
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04679
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1343
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	1.16574
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.942
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
VCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58646
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
Severe COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.0002
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01315
chr17_39965453_G_A_b38	GTEx eQTL 2025	1.0	3.00217
Null cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.139
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07646
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9444
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.7562
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1343
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50917
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.75449
septopallidal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48296
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26751
Respiratory allergy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99011
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926334
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69324
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.30381
RIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5089
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
Perturb_10230_KD_FOXC1_SRP068208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.04539
epidermal hyperplasia	MGI Mouse Phenotype Associations 2023	1.0	null
Cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26128
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45036
tonsil	HPA Tissue Gene Expression Profiles	1.0	0.929119
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9899
LRATD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74053
Nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.011
ISCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38008
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.462
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15973
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77238
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105353
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.4411
Lytic vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.684
gsdmb	GeneRIF Biological Term Annotations	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055092
HDGF_02_104	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.42626
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
phosphatidylinositol-4-phosphate binding	GO Molecular Function Annotations 2025	1.0	null
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97968
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37262
Microglial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.497266
ZSWIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33868
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33135
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64534
Gasdermin	InterPro Predicted Protein Domain Annotations	1.0	null
SAT	DepMap CRISPR Gene Dependency	1.0	2.77196
GA-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3135b	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	450.991
MYO1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76691
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76292
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061579
Pulmonary edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854831
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.635
Cervix disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59993
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36507
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13223
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830921
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15585
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1268
ISGF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98893
Podocyte foot	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54211
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13634
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489057
Respiratory epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
DMRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41669
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1343
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
GTEX-S4P3-1526-SM-3K2AV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824136
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18901
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17467
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.11923
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	73.1345
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51265
SELENOF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24268
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
stomach	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825917
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5163-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Umbilical artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-410	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
hsa-miR-1273e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
asthma	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.561725
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
PMC9285118__F2	PFOCR Pathway Figure Associations 2024	1.0	null
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54736
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67782
vascular disease	GWASdb SNP-Disease Associations	1.0	0.18824
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28438
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03284
alar plate of p1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06176
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
Membrane attack complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.476
CTNNB1	ChEA Transcription Factor Targets	1.0	null
CHOP-C/EBP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42706
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-1.17
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cervical squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52011
life	GeneRIF Biological Term Annotations	1.0	null
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78622
MFE280	DepMap CRISPR Gene Dependency	1.0	2.93356
ZNF195	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60856
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0493
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.5833
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37717
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
Traumatic brain injury	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
CARMIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51432
Endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.954
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35285
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Asthma (time to onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84892
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62608
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2738
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15799
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74583
C1orf174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60358
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00021
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bleb	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0922
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
Gastric pit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
Monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.224
UACC893	DepMap CRISPR Gene Dependency	1.0	3.892
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.3839
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3886
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.071
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
Asthma	dbGAP Gene-Trait Associations	1.0	0.796965
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
Peritonitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41649
nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173314
Necrosis	CTD Gene-Disease Associations	1.0	1.10388
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07301
Obstructive nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
IGF1R_druginhibition_47_GSE14024	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.85882
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00256
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58748
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03673
Skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Nuclear membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.46
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.844664
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.2157
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44067
stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413912
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44267
Vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.21
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.41868
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.5
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.087
Hypereosinophilic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993979
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.7221
TMX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4983
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
Inflammatory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.564
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56982
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19424
pyroptotic inflammatory response	GO Biological Process Annotations 2025	1.0	null
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53743
hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.5306
SMAD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6468
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16221
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04139
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43495
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21624
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
anemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.5306
skin	HPA Tissue Gene Expression Profiles	1.0	2.24241
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5213
Gut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
SRSF9_02_90	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.24793
psmd3	GeneRIF Biological Term Annotations	1.0	null
PGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13476
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52136
abnormal guard hair morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.857
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74827
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24011
eye opacity	MGI Mouse Phenotype Associations 2023	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04995
pattern	GeneRIF Biological Term Annotations	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971506
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXNDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9638
AKAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10696
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.792
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06772
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ST18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67022
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3Y-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased lymphocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853084
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37255
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34876
coarse hair	MGI Mouse Phenotype Associations 2023	1.0	null
PMC7906601-elife-62470-supp4.xlsx-Table_S7_MS_and_siRNA_KD-Supplementary_File_4_Summary_of_HIV-1_splice_variant_interactome_MS_data_and_siRNA_KD_expression_changes_data_Related_to_Figures_2_and_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EXOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47601
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0092
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04113
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	83.1332
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
RNF2_02_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.06609
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21472
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37285
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55336
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_02_183	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.67807
Salmonellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.862
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34325
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7368
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00115
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879225
integumentary system disease	GWASdb SNP-Disease Associations	1.0	0.138947
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24217
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.24378
Respiratory epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.582
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845294
PCI6A	DepMap CRISPR Gene Dependency	1.0	2.16195
single-organism process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17642
STAT3	ENCODE Transcription Factor Targets	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37579
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66883
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54056
EBF1	ENCODE Transcription Factor Targets	1.0	null
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06453
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971506
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.451
Rectum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
rectum	HPA Tissue Protein Expression Profiles	1.0	0.922619
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	86.7802
increased mean corpuscular hemoglobin	IMPC Knockout Mouse Phenotypes	1.0	null
PMC10274772-media-2.xlsx-TFAP2A_motif_in_promoters-TFAP2A_target_genes_with_TFAP2A_motif_in_their_promoter_region_n_64_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
GADD45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1655
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.895858
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97456
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27647
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormal hair cycle catagen phase	MGI Mouse Phenotype Associations 2023	1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94477
Endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.68
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.445
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.086
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937687
hsa-miR-4711-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50173
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96248
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88632
Allergic rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	175.444
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64795
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.648
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37192
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84765
TRIM24_knockout_298_GDS3087	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.53709
RET_druginhibition_184_GSE49414	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.949481
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38599
UBE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4643
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49616
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882759
Mucin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
gsdmlgsdm	GeneRIF Biological Term Annotations	1.0	null
generalized abnormality of skin	GWASdb SNP-Phenotype Associations	1.0	0.136381
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1113
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937687
Marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.277
BB65-RCC	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
closely	GeneRIF Biological Term Annotations	1.0	null
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60309
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23897
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09805
leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355942
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14492
Gastric epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72051
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.217996
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.246
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.1372
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06467
HCMEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06321
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68155
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I5-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.682
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900536
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	378.886
AQP11_Deficiency_GDS3395_578_mouse_Kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
phosphatidylinositol-4-phosphate binding	GO Molecular Function Annotations 2023	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03265
biological_process	GO Biological Process Annotations 2015	1.0	null
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0951
PMC8482521-mmc13.xlsx-Phosphosites_12_hr_48_hr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-922	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38542
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.826014
Systemic Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
Leaflet of membrane bilayer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.818
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7538
DIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19186
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.0994
possibly	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854831
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08735
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00759
oe19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.61495
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66544
EFM-192A	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.025
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88465
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
form	GeneRIF Biological Term Annotations	1.0	null
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.912
Photoreceptor distal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05654
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.976
wrinkled skin	MGI Mouse Phenotype Associations 2023	1.0	null
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Inner mucus layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
hsa-miR-3187-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.7352
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19977
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54056
separate	GeneRIF Biological Term Annotations	1.0	null
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.268
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2646
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pretectal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19452
SLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19065
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28631
outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.556865
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19199
PMC7901903__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.088
Scd1_DELETION_GDS4910_309_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Nascent polypeptide-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.268
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44551
Respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.954
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.922619
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1023
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12223
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07479
ATL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45243
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64087
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7913-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.085
Mitochondrial crista	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6056
abnormal skin condition	MGI Mouse Phenotype Associations 2023	1.0	null
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09061
CLINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78567
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87698
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078044
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.119
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884761
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.999
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.229
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04723
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17159
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.5917
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.849
Gut cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
NRL_Deficiency_GDS1693_236_mouse_Photoreceptors cells of retinas at P2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23066
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11581
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	443.115
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09131
alar plate of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1343
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
gastrointestinal	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0078
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53897
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17436
IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Extrinsic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
Encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
MYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16917
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.46288
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.877
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61215
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06879
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.637495
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901724
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	2.24432
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.016
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.509
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69747
increased lymphocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
thick epidermis	MGI Mouse Phenotype Associations 2023	1.0	null
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52767
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09628
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39457
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1697
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.69458
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.3031
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.333
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57761
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851962
Gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.762
tongue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
PYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02176
SCC9	DepMap CRISPR Gene Dependency	1.0	3.44936
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
Colonic epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1685
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.2182
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6668
Chronic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.123
USP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51316
estradiol_homo sapiens_gpl14550_gse35034	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64237
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42441
SUPM2	DepMap CRISPR Gene Dependency	1.0	2.12553
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21624
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.033
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09661
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
I-cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
FOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15006
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831637
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17365
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
Hair follicle bulge stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ptosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.116
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92216
gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254239
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9923
Superior colliculus, motor related, intermediate white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10873
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
Plasmacytoid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.259
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920488
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28325
Lateral terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45251
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2264
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.049
TFEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63978
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
Hypertrophy	CTD Gene-Disease Associations	1.0	1.31297
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
hsa-miR-4487	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
hsa-miR-4440	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
18625725-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	384.518
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33696
GTEX-Q734-1826-SM-2I3EL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863633
ZNF483	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16355
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ELF1	ENCODE Transcription Factor Targets	1.0	null
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	384.59
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02695
xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496483
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30011
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.278
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79619
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68495
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.69384
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Targets 2022	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.224
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61538
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42513
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1051
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13344
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
layer 6 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30081
Asthma	DisGeNET Gene-Disease Associations	1.0	null
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10637
sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.860521
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81845
Intracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.802
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bacterial sepsis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hematological parameters	GAD Gene-Disease Associations	1.0	null
hsa-miR-3942-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89918
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32706
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
KP1N	DepMap CRISPR Gene Dependency	1.0	3.07288
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4467
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
proteasome core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.590553
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60248
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7059
SUZ12	Pathway Commons Protein-Protein Interactions	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.891
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908032
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53274
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5151-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04723
Lysosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.684
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
Lung squamous cell carcinoma_LUSC_TCGA-22-4605-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42616
GSE190076_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.991415
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2927
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02678
TTLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49518
Lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.216
observations	GeneRIF Biological Term Annotations	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6241
Gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.43
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85591
A-375 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0958
skin epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.796874
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49937
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70322
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.119003
dry skin	MGI Mouse Phenotype Associations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4742-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04027
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12617
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
Adult respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
Asthma	HuGE Navigator Gene-Phenotype Associations	1.0	null
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26948
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14913
J-774 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5025
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964878
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.4
Microvesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.346
EGR1	ChEA Transcription Factor Targets	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57357
intermediate stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91035
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10873
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98235
Eosinophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.664
skin inflammation	MGI Mouse Phenotype Associations 2023	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6479
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46768
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33256
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15793
MICALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59955
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30994
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12829
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18867
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25549
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5075-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.70906
PK1	CCLE Cell Line Gene CNV Profiles	1.0	1.38525
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00805
Respiratory syncytial virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
M1 macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52193
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15106
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.7037
Lipopolysaccharide receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040703
alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.651694
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14492
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95186
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EI-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57021
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236332
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76667
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MUTZ8	DepMap CRISPR Gene Dependency	1.0	2.18758
hypergranulosis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61999
Primary biliary cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39118
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64961
inflammatory abnormality of the skin	GWASdb SNP-Phenotype Associations	1.0	0.25743
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66393
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.877
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21922
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883337
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22899
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061242
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2624
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28017
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07637
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64294
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.47016
SKBR3	DepMap CRISPR Gene Dependency	1.0	3.00883
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41649
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4353-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052026
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90828
ormdl3	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DDX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23791
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02678
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3299
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6035
Secondary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.585
PARK2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866607
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057382
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4225
TES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16584
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35106
Prostate adenocarcinoma_PRAD_TCGA-FC-7708-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine corpus endometrial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
DBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59702
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91035
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854831
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.132
commissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40018
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24717
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.276
hsa-miR-548w	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855933
chr17_39959080_C_CA_b38	GTEx eQTL 2025	1.0	4.56544
chr17_39972395_C_T_b38	GTEx eQTL 2025	1.0	3.42668
DNAJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83046
Cytotoxic T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.057
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965137
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60872
Superior colliculus, optic layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37192
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19452
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08158
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.012
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05571
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-548c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.0073
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90128
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14772
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.701
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02395
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98056
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05299
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
IQGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46925
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60941
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23958
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0308
SAP30	ENCODE Transcription Factor Targets	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054457
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22357
skin disease	GWASdb SNP-Disease Associations	1.0	0.169131
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859554
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47X-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5120-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.318
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.03461
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38584
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68981
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.922619
Rheumatic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
UACC-812	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54579
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10312
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate	GeneRIF Biological Term Annotations	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.372743
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911878
ISCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36115
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27874
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6223-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66922
BV-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57715
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38445
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13824
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55099
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	122.803
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35718
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969664
Biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
Neuroma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.8398
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826057
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41446
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65557
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COV318	DepMap CRISPR Gene Dependency	1.0	2.08132
Perturb_15223_KD_FOXC1_SRP276213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.02851
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32875
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14207
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6201
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9482
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.962
Lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.216
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64318
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25459
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.05389
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.99315
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.1971
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31881
FLI1	ChEA Transcription Factor Targets	1.0	null
insular cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50334
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216933
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6220-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
evolutionary	GeneRIF Biological Term Annotations	1.0	null
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99371
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.724907
PMC11933697-41467_2025_58216_MOESM9_ESM.xlsx-SD7_C_R_NS1_Med_ATF3_DEG-symbol_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02031
MyoD	MotifMap Predicted Transcription Factor Targets	1.0	null
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.269
ZNF442	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13405
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
TMEM14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71544
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3134
directing	GeneRIF Biological Term Annotations	1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82824
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00861
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76489
pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.146457
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52479
TAL1	ChEA Transcription Factor Targets	1.0	null
non-small cell lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
maturation	GeneRIF Biological Term Annotations	1.0	null
Encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
E2F4	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.257358
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30712
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-ZNF205_ZNF205	Rummagene Transcription Factor Associations 2026	1.0	null
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
MTOR_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Osteophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396844
hsa-miR-548b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.612
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24676
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A901-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
childhood-onset asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.528
LN382	DepMap CRISPR Gene Dependency	1.0	2.04697
disorganized corneal epithelium	MGI Mouse Phenotype Associations 2023	1.0	null
Bronchial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.67
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78905
defense response to bacterium	GO Biological Process Annotations 2023	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06991
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8212
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62969
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_6_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.605306
abnormality of skin physiology	GWASdb SNP-Phenotype Associations	1.0	0.25743
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.293677
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13772
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	0.835327
Synovitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
upper	GeneRIF Biological Term Annotations	1.0	null
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85786
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09436
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64694
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
Mhs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.001
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0067
FAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.5
Daudi	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.07274
hsa-miR-548j	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6068
PCSK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31487
ARV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26798
Mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.516
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04834
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.293677
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
PAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60924
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.1692
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05544
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09505
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7969
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.94062
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
Alveolar epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
NCAPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33995
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.679
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333028
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81983
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system disease	GWASdb SNP-Disease Associations	1.0	0.176722
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35172
Asthma (childhood, severe)	GWAS Catalog SNP-Phenotype Associations	1.0	1.07711
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44694
PMC5842026-mmc5.xlsx-HIC1_directTargets_72h-Gene_symbol_HIC1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
CNKSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15145
PDE5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07916
Caspase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Asthma (childhood onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.05229
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23076
Brain infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983517
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33828
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24927
Rheumatoid arthritis disease specific synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
Autosomal recessive nonsyndromic deafness 59	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.937
RFX5_02_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90689
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	5.72835
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4872
Phosphopantothenoylcysteine decarboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
ZNF69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32995
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47305
Cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
PMC10274772-media-2.xlsx-TFAP2A_motif_in_enhancers-TFAP2A_target_genes_with_TFAP2A_motif_in_their_enhancer_region_n_99_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47818
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27217
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19477
PMC9360325-DataSheet_3.xlsx-DEGs_DLPSvsMLPS_54DOWN-Data_file_S3D_Downregulated_DEGs_in_DCATH-2_trained_LPS-stimulated_dTHP-1_cells_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CARD8 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.654
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88457
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04572
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20739
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73945
hsa-miR-4503	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
WDR45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49866
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.933
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00758
Adrenocortical carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86989
NRF1_02_62	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.9386
BAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.948
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41184
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90463
Osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02249
PMC5985538-mmc2.xlsx-selected_2X_in_2_exp_SALL1_FL-Gene_names_SALL1	Rummagene Transcription Factor Associations 2026	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.49396
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20153
Phagophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
collicular (rostral) midbrain tectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12596
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80959
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98764
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	375.181
SP2_02_42	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.22239
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.843
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.24912
AKT_UP_MTOR_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
channel activity	GO Molecular Function Annotations 2025	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040537
Organelle envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.197
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21561
Lung endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
wbc	GeneRIF Biological Term Annotations	1.0	null
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
increased corneal stroma thickness	MGI Mouse Phenotype Associations 2023	1.0	null
UBE2G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88604
ZFPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98728
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96055
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54056
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16495
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.52002
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80658
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6809
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25976
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
PMC9684248__F2	PFOCR Pathway Figure Associations 2024	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
SKES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.58976
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.009
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96638
Systemic scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
FOXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74386
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52812
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02941
epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245807
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40701
STAT4-19710469-TH1 cell mouse-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4872-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.88
PMC11657369-12951_2024_3025_MOESM2_ESM.xlsx-PC-3-NR2F1-AS1-pulldown-Gene_names_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.884009
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253578
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102653
Allergic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	114.844
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31017
bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.915963
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.38876
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07107
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91035
MFE-280	COSMIC Cell Line Gene CNV Profiles	1.0	2.23324
LHX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62781
RERF-LC-MS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63056
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraseptal subpallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2956
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0738
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85251
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.27151
GPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84227
hsa-miR-4747-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.01766
mantle zone of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10873
abnormality of the skin	GWASdb SNP-Phenotype Associations	1.0	0.104541
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.116
Osteomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22646
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855933
cancers	GeneRIF Biological Term Annotations	1.0	null
White blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.0699
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A1_02_84	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.35755
Lung epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46886
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Bronchial epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.58
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86514
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94512
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.871
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040365
Brain edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02264
Extracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.071
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02678
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Neurilemoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.54
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12586
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.269
VAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32708
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6907
Bone marrow-derived dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
pit	GeneRIF Biological Term Annotations	1.0	null
snps	GeneRIF Biological Term Annotations	1.0	null
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.289
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82429
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73448
ANAPC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78599
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59957
MM370	DepMap CRISPR Gene Dependency	1.0	2.0423
Uterine corpus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32345
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06991
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.469
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6619
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
nausea and vomiting	GWASdb SNP-Phenotype Associations	1.0	0.870579
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47735
Brain glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
Transforming growth factor beta activated kinase 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.687
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
Alcoholic hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52221
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	236.528
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	117.526
AU565	DepMap CRISPR Gene Dependency	1.0	3.39365
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20098
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063986
Large granular lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.146
NAA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14553
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373868
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18328
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71094
dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050629
19605494-TableS3	GeneSigDB Published Gene Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17532
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17828
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22077
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.025
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	1.50166
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.269
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22178
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
DHRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66761
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.033
U2-type catalytic step 1 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.412
mesomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12596
OCUBM	DepMap CRISPR Gene Dependency	1.0	3.7299
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0612
Lung squamous cell carcinoma_LUSC_TCGA-94-A4VJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177519
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53776
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hair follicle development cytodifferentiation stage 3 of 3	WikiPathways Pathways 2024	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03179
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968801
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52374
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1343
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92807
Crohn Disease	DisGeNET Gene-Disease Associations	1.0	null
subjects	GeneRIF Biological Term Annotations	1.0	null
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55757
amplicon	GeneRIF Biological Term Annotations	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18211
Bacterial outer membrane vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.406
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
abnormal corneal stroma development	MGI Mouse Phenotype Associations 2023	1.0	null
abnormal epidermal layer morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1917
EFO21	DepMap CRISPR Gene Dependency	1.0	2.1363
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74755
il17	GeneRIF Biological Term Annotations	1.0	null
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal skin physiology	MGI Mouse Phenotype Associations 2023	1.0	null
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91797
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.122
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	271.273
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
VHL_Deficiency_GDS3769_513_mouse_Immortalized embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60665
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.623446
Esophageal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45148
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.957933
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43713
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4alpha_KO_GDS1915_173_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02787
pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288514
Asthma and hay fever	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
PMC9170928__F8	PFOCR Pathway Figure Associations 2024	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.878
Rhinitis, Allergic, Seasonal	HuGE Navigator Gene-Phenotype Associations	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65492
IkappaB kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.567
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06269
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7519
GSE173169,GSE173170_0_v_1_epc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.149
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT4	ChEA Transcription Factor Targets	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996054
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42279
Glomerular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53533
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.991975
Urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Lung endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055112
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.70233
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4782-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66824
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14538
Silicosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-3.13513
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18129
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0264
Hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.441
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02678
Gout	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.983
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.715
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866115
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PANC0403	DepMap CRISPR Gene Dependency	1.0	2.41011
hsa-miR-548d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
RMGI	DepMap CRISPR Gene Dependency	1.0	2.21409
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41272
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19454
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251606
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325335
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50251
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.922299
Acute myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.448
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906