association	dataset	threshold value	standardized value
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.87206
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63045
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.39576
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0756
PMC2882232__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98438
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.014
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85798
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228177
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22335
Kidney Chromophobe_KICH_TCGA-KL-8343-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.833254
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.90964
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2448
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33557
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979265
SARS-dORF6_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.43477
JHOM2B	CCLE Cell Line Gene Expression Profiles	1.0	1.65606
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906005
lethality throughout fetal growth and development, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79428
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02349
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68756
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Y-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249652
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00751
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24526
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29979
Lung adenocarcinoma_LUAD_TCGA-38-4628-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15488
Brain Lower Grade Glioma_LGG_TCGA-HT-A616-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930558
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32413
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF282	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64137
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6128
golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
protein kinase inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891569
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829894
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYO1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11693
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4U-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.18597
INCB 3284	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2429
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65954
u251mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.853779
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0668
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2503
PPARD_KO_GDS4320_619_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TRPM7_overexpression_305_GSE23102	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.37666
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5832
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56929
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07391
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.842669
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75829
AT9283	DGIdb Drug Targets 2026	1.0	4.812
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4239_KO_Ddx5_SRP187042	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.55251
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04624
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90715
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00826
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02489
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09994
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20292
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	1.0	1.18845
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906005
Prostate adenocarcinoma_PRAD_TCGA-EJ-5516-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50806
SNU601	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87199
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02995
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	4.58764
ac88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
PMC5108588__F8	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35334
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.99511
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948256
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	1.50496
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34566
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.43685
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06124
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15227
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A82F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2294
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00783
4951_MED28_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.21223
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35113
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
fusiform gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873633
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15024
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-PKNOX1_mod_PKNOX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.54418
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29406
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14568
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868504
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872661
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225266
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03368
regulation of Wnt signaling pathway	GO Biological Process Annotations 2025	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906195
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-QDVN-1026-SM-48TZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24672
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940166
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19903
intrinsic apoptotic signaling pathway in response to oxidative stress	GO Biological Process Annotations 2023	1.0	null
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31057
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.1197
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922022
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25286
abnormal hard palate morphology	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-758	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17103
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.939
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04042
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
icSARS CoV_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.46771
chr14_96360910_A_T_b38	GTEx eQTL 2025	1.0	1.5921
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00909
PMC10350077-media-7.xlsx-microglia_proteomics_LPS-Gene_Symbol_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59771
FRAT2	Pathway Commons Protein-Protein Interactions	1.0	null
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03498
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80219
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040126
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35686
Perturb_3122_KO_Slc6a14_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43316
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911464
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26692
GTEX-T6MO-1126-SM-4DM5D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913342
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78204
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55217
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37579
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36292
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8397
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2243
HCC1588	CCLE Cell Line Gene Expression Profiles	1.0	2.06334
Childhood infratentorial ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12284
IEC-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24396
NTERA-2-cl-D1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.10123
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929409
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34098
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7324530__F1	PFOCR Pathway Figure Associations 2023	1.0	null
NCIH1694	CCLE Cell Line Gene CNV Profiles	1.0	2.20012
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09924
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18324
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24136
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18386
hsa-miR-659	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
Perturb_13047_KO_YAP1/WWTR1_SRP212218	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.5176
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16816
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975189
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00522
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34801
PC14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47065
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839469
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58324
Intracranial meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31413
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02143
KYSE30	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68857
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31251
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44872
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.606089
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
18535662-TableS2c	GeneSigDB Published Gene Signatures	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3279
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906244
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	1.0	2.02324
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
AB-84-PK04_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306453
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948582
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00372
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08995
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13637
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847921
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.925
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14305
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65287
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11947
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89752
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39829
GSE114992,GSE114993_9_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19742
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
umbilical cord blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.561808
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66701
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252861
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
7996_SLC25A26_ENST00000354883.6	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.622353
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051922
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22998
hsa-miR-342-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837505
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44454
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15169
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01891
Type 1 diabetes mellitus 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2164
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15814
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.76009
hsa-miR-4724-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_8843_KD_PPARGC1B_SRP254908	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_9617_KD_LKB1_SRP045048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0YX-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23243
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25291
Perturb_16581_KO_Cited2_SRP321006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.91694
GSE95688_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
wnt	GeneRIF Biological Term Annotations	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03341
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01336
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.31152
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43974
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE57871_5_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60541
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21147
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC1	CCLE Cell Line Gene Expression Profiles	1.0	1.37079
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838939
Perturb_4521_KO_Mapk1/Mapk3_SRP281895	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.10142
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10516
KMBC2	CCLE Cell Line Gene Expression Profiles	1.0	1.80557
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04569
EJM	CCLE Cell Line Gene Expression Profiles	1.0	1.57957
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5006
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20085
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	3.54343
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888468
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84448
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.837358
inner CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926636
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63201
AKAP11	Pathway Commons Protein-Protein Interactions	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56994
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EM2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.52629
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.07179
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906005
GATA2_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66548
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08222
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98882
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27379
ZNF143	ENCODE Transcription Factor Targets	1.0	null
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250206
GSE147240_3_v_4_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CB-11-GB40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212789
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886494
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26978
Perturb_5967_KD_SUV39H1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.89923
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841253
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21441
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17151
Perturb_11776_KO_Abca8b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.54175
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16504
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.484
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18324
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.99416
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18324
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.3479
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67902
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10059
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14468
Perturb_216_KO_Gpd2_SRP361070	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.39944
LU-65	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.1661
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282184
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29073
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1085_KD_MYEOV_SRP242311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7014
able	GeneRIF Biological Term Annotations	1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1071
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844525
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97468
GSE194358,GSE194361_0_v_1_kdm5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
697 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15905
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04189
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
Laryngeal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
RPL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21825
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64302
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDEM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20269
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40212
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86846
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_0_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CL34	CCLE Cell Line Gene Expression Profiles	1.0	1.96709
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02205
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13637
20081105-Table5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98374
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.960943
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.07331
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08213
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48427
IRF8-22096565-GC-B-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4567_KD_Smc1a_SRP172038	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.63722
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29662
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973551
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949741
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5541666__F1	PFOCR Pathway Figure Associations 2023	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-1.28678
Protein of unknown function DUF727	InterPro Predicted Protein Domain Annotations	1.0	null
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495579
MIB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.009
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.62742
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
Perturb_11828_KO_Ptpdc1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31717
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A2PC-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hydroxyl	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Transient myeloproliferative syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
ABC1_LUNG	CCLE Cell Line Proteomics	1.0	10.2325
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923892
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.55228
GSE200352_5_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36307
HCC1187_BREAST	CCLE Cell Line Proteomics	1.0	2.09215
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Cervix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05473
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62717
intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913335
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.03972
Perturb_3760_KD_TSG101_SRP325061	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.88909
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.43685
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41618
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19152
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38054
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36241
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01076
Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42523
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42886
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04125
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
appendix	HPA Tissue Protein Expression Profiles	1.0	0.83367
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25793
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86684
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93477
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01617
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68432
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.933054
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.22255
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53311
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10785
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32334
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06293
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.63797
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901082
TAL1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50388
superficial stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05274
nfe2l2_20133372_lung_lof_mouse_gpl1261_gds3622	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.566124
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40099
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48488
Sulcotrione	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27673
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62098
Sweat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834368
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0187
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.06664
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847225
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33192
rectum	HPA Tissue Gene Expression Profiles	1.0	0.971686
3570_GTF2E2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.544854
GSE255680_1_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.08899
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931317
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
Perturb_4607_KD_H2A.Z_SRP345495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.59044
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20019
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
UNC2881	DeepCoverMOA Drug Mechanisms of Action	1.0	0.79
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4690-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00203
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1257	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52178
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941122
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28648
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29966
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04822
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57617
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864069
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WW-01A-22R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.65229
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20493
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47506
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05646
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ4-2826-SM-3P617	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34061
NS309	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4156
OSC-19	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7386
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4760-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Perturb_11419_KD_CD95L_SRP302700	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80619
Megakaryoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.875168
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1c-List_of_1682_genes_differentially_regulated_by_GLI1_FDR_0_1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06751
EOMES	ChEA Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25011
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08811
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03471
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE224311_3_v_0_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.88967
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16734
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09145
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Laryngeal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.978218
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85645
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27679
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906005
blood vessel	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13175
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00364
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30082
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARS-CoV_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.26687
KDM4C_natural variation_GSE41040_590_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FRAT1	Pathway Commons Protein-Protein Interactions	1.0	null
COLO320	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5059
Lung squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
Prostate adenocarcinoma_PRAD_TCGA-M7-A725-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U3-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912858
Umbilical cord blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.821
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04248
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.983945
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69643
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8623
BICR16	CCLE Cell Line Gene CNV Profiles	1.0	2.16768
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53548
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05136
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BN-01A-61R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00909
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44175
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839516
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.23684
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14721
Cervical squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33129
GTEX-P4PP-0626-SM-3NM9X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05298
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-9	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-320b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940304
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bipolar Disorder_Lymphocyte_GSE7036	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.04349
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829815
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29369
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
(RS)-PPG	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
PMC7338542-41389_2020_247_MOESM5_ESM.xlsx-BRN2_2_of_3_UP_48_h-Symbol_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
PRKACA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40001
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rectum_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.898427
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Perturb_16947_OE_Mir181a1_SRP359086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.42955
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21198
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02058
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03116
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.952768
GSE137818_5_v_0_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gsk3beta	GeneRIF Biological Term Annotations	1.0	null
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table5_Fig_S-Supplemental_Table_5_The_Effect_of_Drugs_on_LPS_induced_Tolerant_Cells_Supplementray_Fig_1D_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-NFKB1_mod_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835295
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.852407
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14251
GTEX-S7SF-0926-SM-4AD4M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825759
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57148
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05718
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50566
PRPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03404
KDM5A	ChEA Transcription Factor Targets	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206743
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5151
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5161753__F5	PFOCR Pathway Figure Associations 2024	1.0	null
negative regulation of kinase activity	GO Biological Process Annotations 2023	1.0	null
Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.92504
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28455
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342499
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	1.38932
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20557
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77587
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970681
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21251
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.04142
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42938
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.19407
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.32209
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839641
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.997273
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3ER-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Promyelocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60761
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5234
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837759
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44793
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48375
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03035
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13032
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SiHa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42027
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.175
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2492
PMC5451507__F2	PFOCR Pathway Figure Associations 2023	1.0	null
hsa-miR-320c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2882232__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74441
PMC12510534-pone.0332407.s001.xlsx-S1_Table-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31569
Perturb_10885_KD_Mafg_SRP165897	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.72883
GTEX-WEY5-0926-SM-4LMI4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902064
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1179	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Perturb_10719_KO_Nrf2_SRP336215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.26953
GTEX-V955-1126-SM-4JBH3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830405
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45684
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6181
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17544
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886169
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.924835
hsa-miR-219-2-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
VCAP_PROSTATE	CCLE Cell Line Proteomics	1.0	2.06472
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07032
hsa-miR-1909	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6288
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46001
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60157
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23011
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1749
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TAL1	ChEA Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82676
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93141
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989538
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39006
LOUNH91	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86841
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33645
PMC3680531-cc-12-1510-s01.pdf-20-ZNF655_ZNF655	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16903
GSE124375_13_v_12_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hep3b2.17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35809
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58305
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.19717
Cul4B-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
OVMANA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66516
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95848
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04031
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03416
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Zofenopril	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
UMRC2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04959
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11877
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52814
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12192
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03868
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57144
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03813
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938445
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08849
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22626
SARS-BatSRBD_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.25293
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03035
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051268
regulation of Wnt signaling pathway	GO Biological Process Annotations 2023	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27144
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20688
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97715
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19228
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2774
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11509
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991388
SMARCA4	ChEA Transcription Factor Targets	1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31324
8651_TAF10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.651919
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00295
PMC5337147__F2a	PFOCR Pathway Figure Associations 2024	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7973
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16881
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8888
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02776
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02353
Retigabine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
Myeloproliferative neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.755
PMC11618734-ac4c05127_si_004.xlsx-OPTI-PISA_automated_MTX_900ng-Unnamed_2_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50414
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67882
protein kinase regulator activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40917
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22455
GSE201309_1_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35788
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.056
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34595
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.324
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972092
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01354
prostate	HPA Tissue Protein Expression Profiles	1.0	1.43685
Parabrachial nucleus, lateral division, ventral lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03976
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3297
PMC4944136-srep28995-s2.xls-DUXA-gene_DUXA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28516
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.91222
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3NI-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21121
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28138
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42885
SNUC1	DepMap CRISPR Gene Dependency	1.0	23.24
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878736
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12685
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2909
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4618
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NUDT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93228
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
bond	GeneRIF Biological Term Annotations	1.0	null
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.878
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22171
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841433
homologous	GeneRIF Biological Term Annotations	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.845012
HIPK2_defectivemutant_17_GDS1793	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.97686
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81321
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr14_96385734_T_C_b38	GTEx eQTL 2025	1.0	2.77856
CL40	CCLE Cell Line Gene Expression Profiles	1.0	1.35509
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995053
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16429
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16301
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1254
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45525
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19698
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.957512
SYK_druginhibition_282_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.50515
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09232
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53539
hydrogen	GeneRIF Biological Term Annotations	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969972
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47137
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06524
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic apoptotic signaling pathway	GO Biological Process Annotations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843745
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07507
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.970697
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
rectum	HPA Tissue Protein Expression Profiles	1.0	1.43685
PMC7599793__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35261
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43762
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.37142
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.04734
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953509
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62256
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1745
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59773
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
ESO51	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.82732
structures	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856406
Perturb_6228_KO_Mbnl1/Mbnl2_SRP142522	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.72998
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405134
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305915
ovary	HPA Tissue Gene Expression Profiles	-1.0	-1.02446
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17818
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08913
SK-MES-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49403
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2467_KO_NAT10_SRP388804	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33034
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986233
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05939
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881101
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43601
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26635
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935247
Inner mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243918
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2343
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826986
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.84719
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925236
Perturb_16778_KO_Tbet_SRP120994	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.13697
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860173
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09292
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9616830-42003_2022_4093_MOESM3_ESM.csv--Zhang2019_FOXN4_cell_FOXN4	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-5337-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90799
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
VMRCRCW	CCLE Cell Line Gene Expression Profiles	-1.0	-2.89334
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206147
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56576
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82693
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45848
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57617
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4726-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12367
Perturb_3251_KD_RBM38_SRP091017	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.9266
Perturb_16714_KO_Selenbp1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45338
GTEX-S4P3-1226-SM-4AD4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38324
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942652
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.177
ERG	ChEA Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838171
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4576
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835463
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26993
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.997618
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.935948
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23431
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11088
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3415-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RASSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22603
CDK8_knockdown_129_GSE30816	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.48759
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871531
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16324
H3K36me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49108
PMC4344387__F1	PFOCR Pathway Figure Associations 2024	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7504
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17357
4379_KIF18A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.602689
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1552
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.82615
positive regulation of canonical Wnt signaling pathway	GO Biological Process Annotations 2023	1.0	null
Sumatriptan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69311
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
Vorinostat	DeepCoverMOA Drug Mechanisms of Action	1.0	1.62
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85083
Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WT1	ChEA Transcription Factor Targets	1.0	null
METTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22491
Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_10_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.436652
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25693
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82395
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04967
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991196
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880721
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41166
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17674
PMC5541666__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intrinsic apoptotic signaling pathway	GO Biological Process Annotations 2025	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kinase binding	GO Molecular Function Annotations 2025	1.0	null
protein kinase A regulatory subunit binding	GO Molecular Function Annotations 2023	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.216
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47924
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
protein kinase inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11954
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858692
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TV-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPB41L3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-548p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
GSE112860_5_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92821
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86084
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8525
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SKCO1	CCLE Cell Line Gene Expression Profiles	1.0	1.69839
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3081
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72191
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15375
Myelocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45613
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0335
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47118
NCIH1568_LUNG	CCLE Cell Line Proteomics	1.0	3.39486
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326072
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28467
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24954
EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63314
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.533156
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948553
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_1_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64243
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4876
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.16052
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88053
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37909
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5027
NCI-H2172	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.05229
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12494
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00137
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYKNU_OVARY	CCLE Cell Line Proteomics	1.0	2.41939
FA-92-JL46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216863
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00886
GE-63-WI86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246037
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984634
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10339
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79892
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cuboid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.842
SETDB1	ChEA Transcription Factor Targets	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
kinase inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21233
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50428
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40888
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09465
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ALDH1A2_KO_GDS4836_290_mouse_anterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
2-Bromophenethylamine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
SMYD2	Pathway Commons Protein-Protein Interactions	1.0	null
positive regulation of Wnt signaling pathway	GO Biological Process Annotations 2025	1.0	null
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23088
PMC12828823-BLOODA_ADV-2025-017980-mmc1.pdf-3-GATA2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
chr14_96363513_G_T_b38	GTEx eQTL 2025	1.0	1.25244
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0366
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24986
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836036
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6004_KD_CEBPZ_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
chr14_96376339_G_GC_b38	GTEx eQTL 2025	1.0	1.00483
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BV173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50756
GSE135334,GSE136010_2_v_3_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.117
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14505
PMC7849364-supp_gad.342378.120_Supplemental_Table_S4_.xlsx-Hoja1-Table_S4-_SIX2-associated_genes_identified_by_CUT_RUN_overlapping_with_differential_expression_by_SIX2_knockdown_SIX2	Rummagene Transcription Factor Associations 2026	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23794
Perturb_10308_KO_Pkd1_SRP128475	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.30649
Perturb_12324_KD_PHF20L1_SRP188318	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03834
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22417
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85007
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26637
GATA3	ChEA Transcription Factor Targets	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82638
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905111
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21539
EZH2	ENCODE Transcription Factor Targets	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863685
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05323
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942652
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05272
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.269
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SK-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8215
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05142
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05927
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LS513	CCLE Cell Line Gene Expression Profiles	1.0	1.74544
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047802
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982369
GSE143782_6_v_8_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
xray	GeneRIF Biological Term Annotations	1.0	null
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01881
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02206
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.42788
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00522
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51336
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.51358
negative regulation of kinase activity	GO Biological Process Annotations 2025	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25422
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07183
hsa-miR-888	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2965-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11757_KD_Gatm_SRP330646	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.46906
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54183
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.859677
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7339546-12915_2020_793_MOESM2_ESM.xlsx-Table_S12-Table_S12_common_twin_genes_in_one_HMR_core_region_between_cattle_and_human_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3690_KD_NUF2_SRP352847	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.45366
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16358
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.962603
GTEX-XGQ4-1226-SM-4AT67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895994
Essential thrombocythemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
colon	GTEx Tissue Gene Expression Profiles	1.0	1.64305
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.66919
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888505
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66225
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6552
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18963
Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.65
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1464
HEL	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48589
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901811
negatively	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-634	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SNU-387 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31697
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20441
Perturb_446_KD_FOXP1_SRP127520	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975912
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.945886
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8301
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0491
PMC8775565__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22369
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
RET_mutant_23_GDS3319	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.30409
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48421
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824908
PMC7037748__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PSN1	DepMap CRISPR Gene Dependency	1.0	3.03713
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18302
Perturb_4324_KO_Btg1_SRP325922	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.88067
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17659
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05436
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853373
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16562
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19177
MXI1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.32386
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
H3K36me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
naturally	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4293	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
delayed bone ossification	MGI Mouse Phenotype Associations 2023	1.0	null
abnormal palatal shelf morphology	MGI Mouse Phenotype Associations 2023	1.0	null
HCC4006	CCLE Cell Line Gene Expression Profiles	1.0	1.49603
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46247
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9468
Hepatopancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0702
Prostate adenocarcinoma_PRAD_TCGA-G9-6499-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79035
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sigmoid_Colon	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.95321
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13129
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10837
Perturb_4988_KO_Ythdc1_SRP212677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.19939
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30902
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852429
hsa-miR-4485	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841244
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5161753__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Sima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07852
PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSSK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32417
DICER1_KO_GDS4504_583_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
PSMD1	Pathway Commons Protein-Protein Interactions	1.0	null
YWHAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25203
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50203
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56516
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16943
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.90693
Perturb_2698_KD_EXOSC8_ERP005739	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Parabrachial nucleus, lateral division, dorsal lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1372
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847595
SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27142
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921105
lm9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
beta-catenin destruction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.271
group	GeneRIF Biological Term Annotations	1.0	null
SU-DHL-4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.18521
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4519	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851549
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867667
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47059
hsa-miR-146b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
LY2090314	DeepCoverMOA Drug Mechanisms of Action	1.0	0.97
Pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
NCI-H1694	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	175.997
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64983
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04748
PMC9490101-mmc3.xlsx-Sheet1-Supplementary_Table_3_Differentially_expressed_genes_in_CASC11_KD_MHCC-97H_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123022,GSE123030_2_v_6_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46439
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3676
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824062
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961949
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43688
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Arnt::Hif1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2212
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99298
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSP90-CDC37 chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
RAB3A_Mutation - D77G point mutation_GDS2483_697_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11595
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_6048_KD_PIAS2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35974
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.09437
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
myelodysplastic/myeloproliferative neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.898586
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37609
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4044
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24248
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02047
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941727
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039451
Lung squamous cell carcinoma_LUSC_TCGA-22-4607-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE234767,GSE234769_3_v_1_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50227
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_N1-GOPC_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62944
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984132
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.182749
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55148
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935507
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4504
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.875
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01336
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833642
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839886
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01967
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15869
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02765
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976616
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36867
CLASP2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11722_KD_Poldip2_SRP303067	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.23987
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28457
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367753
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926475
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9386
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
BxPC-3	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.67381
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC4344387__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17833
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86825
hsa-miR-4495	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06378
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27843
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52603
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
axin	GeneRIF Biological Term Annotations	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37882
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317999
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949207
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06462
SNU81	CCLE Cell Line Gene Expression Profiles	1.0	1.46938
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.715
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856613
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893503
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849084
Perturb_18563_KO_Tal1_SRP117185	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.53749
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23933
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01744
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14194
Orbital area, ventrolateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06181
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915677
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sh-sy5y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07309
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.085
SN12C	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.33894
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04471
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53703
MELJUSO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83798
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12332
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.98594
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37692
SNU61	CCLE Cell Line Gene Expression Profiles	1.0	2.08896
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4211
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03037
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32232
creb1_22108299_heart_left_ventricle_lof_mouse_gpl1261_gds3660	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.010781
mesoderm	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94059
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.850225
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.9377
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27144
Perturb_5968_KD_SUV39H1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.40268
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36625
cleft secondary palate	MGI Mouse Phenotype Associations 2023	1.0	null
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2113
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.966856
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.803
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12253
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204533
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96946
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845136
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23327
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76724
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95695
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.6901
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16429
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31145
PMC4944136-srep28995-s2.xls-ARGFX-gene_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03106
MAFF	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08781
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855335
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98935
rectum_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.848128
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.10296
SNU-175	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.68533
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.553
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TE-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.390769
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-449 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041424
SARS-CoV_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75433
Sarcoma_SARC_TCGA-QQ-A5VB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88947
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925747
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89799
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894083
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXP1	ChEA Transcription Factor Targets	1.0	null
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15185
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981336
palatal shelves fail to meet at midline	MGI Mouse Phenotype Associations 2023	1.0	null
GSE236511_1_v_0_ngfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436726
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839867
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_37_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
cisplatin_homo sapiens_gpl570_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE127205_1_v_0_asf1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54049
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0817
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62986
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07462
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mirabegron	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12544
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418805
CB-11-GB40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289424
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957842
Perturb_3481_KO_Ccn1_SRP304010	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.89156
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49164
GSE193993_4_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26767
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IM95	CCLE Cell Line Gene Expression Profiles	1.0	2.63086
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157555,GSE157556_5_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90888
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876982
8738_TBL3_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.43062
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.903049
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46874
occurring	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17753
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-257-FOXN3_FOXN3	Rummagene Transcription Factor Associations 2026	1.0	null
umbilical cord	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.19134
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DV90	CCLE Cell Line Gene Expression Profiles	1.0	2.48821
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15551
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07467
Perturb_12663_KD_SLNCR1_SRP070082	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.2663
SIN3B	ChEA Transcription Factor Targets	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943093
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21432
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63766
SKRC31	CCLE Cell Line Gene Expression Profiles	-1.0	-3.60576
Eplerenone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
OCIAML3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19514
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20638
PMC11950762-BLOODA_ADV-2024-014354-mmc2.pdf-22-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24131
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41374
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879772
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1254
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48413
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GN-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4529_KD_Chaf1b_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.67936
hsa-miR-3671	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6008
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47924
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241303
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899671
regulation of signal transduction	GO Biological Process Annotations 2025	1.0	null
Myelofibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43516
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968809
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.17025
IRF8	ChEA Transcription Factor Targets	1.0	null
GSE108614,GSE108615_0_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHOM1	CCLE Cell Line Gene CNV Profiles	1.0	1.33106
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14261
protein kinase binding	GO Molecular Function Annotations 2025	1.0	null
GSE176008_4_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-19a	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14255
Lung squamous cell carcinoma_LUSC_TCGA-18-3412-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-218	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50005
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66679
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RRP7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41356
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17092
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201246
A-CA-04-2009(H1N1)_24Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.17101
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83843
Synaptic vesicle protein transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.063
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21879
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40913
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2334
DLX5_Deficiency_GDS4443_356_mouse_E10.5 embryos otic vesicle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0343
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09675
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.89293
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35129
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50343
KYSE-410	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.1754
hsa-miR-330-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32907
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47333
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824945
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04654
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04243
Integral component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1254
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02937
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.00509
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04078
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18382
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22838
Perturb_5288_KD_Rpl10a_SRP064202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.62015
Perturb_14040_KO_Mbd1/Mbd2/Mbd4/Mecp2_SRP337936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.25957
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83433
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37215
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4613
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49299
primary atelectasis	MGI Mouse Phenotype Associations 2023	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.981586
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13228
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68747
Perturb_17510_KD_Klf4_SRP338421	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.41614
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955489
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37882
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.973381
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06611
NCIH1694	CCLE Cell Line Gene Expression Profiles	1.0	1.37856
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11696
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41905
hsa-miR-4429	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19491
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3785
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41865
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5797
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905524
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49338
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838361
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20762
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.937639
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.67618
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.739156
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.856184
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.31393
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56014
cisplatin_homo sapiens_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04648
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948736
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.640306
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8525
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10111
CLDN18_KO_GSE48443_44_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.869496
Perturb_3923_KD_VPS37B_SRP266781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.54044
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.932625
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19778
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99593
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41701
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43991
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77497
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25044
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994986
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.845375
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17924
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.08932
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3470785-NIHMS377161-supplement-12.pdf-481-ZNF395_ZNF395	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15179_KD_AIM2_SRP404341	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.00467
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95884
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17247_KD_Brd2_SRP201499	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.71974
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.319
DNAJC2	ChEA Transcription Factor Targets	1.0	null
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2359
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.74199
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963109
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59567
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02395
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	1.0	1.37424
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IJ-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53489
MAZ	ENCODE Transcription Factor Targets	1.0	null
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Polycythemia vera	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
germ layer	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87215
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051006
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12325
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905939
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
regulation of canonical Wnt signaling pathway	GO Biological Process Annotations 2023	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7886-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.99976
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34105
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46197
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45856
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.58438
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999098
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulate	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.70529
PMC6823153-NIHMS1535502-supplement-3.xlsx-LSD1_SupplData1-Supplementary_Data_1_Potential_common_target_genes_of_LSD1_and_GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05125
NCIH2228_LUNG	CCLE Cell Line Proteomics	1.0	4.4044
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22977
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266816
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.837414
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26925
complexes	GeneRIF Biological Term Annotations	1.0	null
maintaining	GeneRIF Biological Term Annotations	1.0	null
Nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80671
SARS-CoV_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6883
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39403
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7XN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNDZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40872
JL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43095
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96139
colonrectum_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16449
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10623
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50535
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9083
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9833
TAL1_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3402
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0686
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868504
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.33477
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84108
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884883
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7138
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.08753
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40619
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
CORL105_LUNG	CCLE Cell Line Proteomics	1.0	9.84865
Perturb_13172_KD_Birc6_SRP115807	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13663
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43672
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828047
pallor	MGI Mouse Phenotype Associations 2023	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.081619
SNUC4	CCLE Cell Line Gene Expression Profiles	1.0	1.73215
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085437
PMC9348619__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
t56-vastus-lateralis_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.35931
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917908
PMC7599793__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Enzastaurin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.82
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.6125
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895202
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934108
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976996
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17337
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03329
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951003
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04388
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20419
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2025
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46412
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51586
Grey cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.216
STK416816	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7010_RAB18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.729906
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4011
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87731
Nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
egr1_20019881_retina_lof_mouse_gpl1261_gds3607	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.546965
HOP92	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34559
POU3F2	ChEA Transcription Factor Targets	1.0	null
STK066844	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.42
hsa-miR-3074-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
colon_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06239
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34491
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978147
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902208
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54224
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89744
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998534
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73439
MAFK	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62728
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878646
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7421
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1805
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40337
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858217
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23622
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4670-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_3900_KO_TCF7L2_SRP314475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991533
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7644-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP36_Deficiency_GDS2456_707_mouse_Fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48668
ERG-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_3250_KD_RBM38_SRP091017	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.51204
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31737
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16872
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67214
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.922003
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03115
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05913
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.85729
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06812
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23436
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22455
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6968
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.39774
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35687
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863685
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978493
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84988
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29T-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3689_KD_NUF2_SRP352847	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.434
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.155733
MLST8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30139
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06682
SB-29-ZH97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213456
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.971
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.913589
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855156
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sk-n-sh cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226496
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5551
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	3.02854
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588432
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3472
EOMES-21245162-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1426-SM-3MJHC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.84569
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04242
PPP1R3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21308
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03922
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14731
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10152
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5269
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.897707
253J	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15447
Rectum adenocarcinoma_READ_TCGA-EI-6882-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AXIN1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7915
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.799036
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30605
MYCN	ChEA Transcription Factor Targets	1.0	null
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Down_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4715-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
RPL29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09719
CHP-126	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.73953
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.11981
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2309
NCIH1869	DepMap CRISPR Gene Dependency	1.0	3.25755
Small intestine cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05804
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5951
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903011
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2826-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-320d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55249
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837707
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998666
PMC12866144-mmc3.xlsx-Sheet1-Table_S2_List_of_genes_that_comprehend_the_TP53_AML_signature_generated_in_this_manuscript_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-3688-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10314
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-3607-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08662
Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35184
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.904466
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27264
Prostate adenocarcinoma_PRAD_TCGA-CH-5745-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21802
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39955
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874388
SYK_druginhibition_287_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.71846
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64555
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215875
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883651
PMC7037748__F1	PFOCR Pathway Figure Associations 2023	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057723
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65471
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
negative regulation of protein phosphorylation	GO Biological Process Annotations 2025	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14176
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17685
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08219
Perturb_9129_KD_KDM2B_SRP359233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.3475
Hs-683	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.36286
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888505
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66891
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.43685
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
496100547_HIP_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03077
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838301
EP300	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4303	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08995
Mianserin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81745
KP-N-YS	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.61021
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855152
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12130_KO_Ldb1_SRP136181	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.14862
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-543	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10587
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6039
Prostate adenocarcinoma_PRAD_TCGA-J4-A67T-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pdx1_22135308_duodenum_lof_mouse_gpl1261_gds4348	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.199367
PMC3680531-cc-12-1510-s02.pdf-23-ZNF655_ZNF655	Rummagene Transcription Factor Associations 2026	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	7.56626
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98269
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58854
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993803
JVE127	DepMap CRISPR Gene Dependency	1.0	7.74224
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0215
hsa-miR-664	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252938
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041153
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.90737
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45313
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925097
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21853
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0339
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77005
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01429
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.23505
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947879
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.0635
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12353
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37111
EM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40049
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933265
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
artery	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868291
CD-80-ZD47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237308
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
crucial	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14865
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	171.533
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1475
HULC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.464
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01424
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948553
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MPHOSPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00714
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10907
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05359
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17978
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52195
vascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36301
NCIH23	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4753
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05888
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.24289
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210885_2_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	1.0	2.26246
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93858
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.49137
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8579
Perturb_4573_KO_Pwwp2a/Pwwp2b_SRP255880	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.08814
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903605
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134385
rectum_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.05857
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13776
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98563
PEX19	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22683
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23523
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2519
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51377
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99925
GSE221577_1_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.3143
hnf4a_16714383_e18dot5_liver_lof_mouse_gpl1261_gds1916	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.316957
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.401
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82238
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870486
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39473
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	GO Cellular Component Annotations 2025	1.0	null
negative regulation of protein phosphorylation	GO Biological Process Annotations 2023	1.0	null
MEL-JUSO	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.20917
PPP1R2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897365
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057927
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917123
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72254
Perturb_1126_KO_Myc_SRP168941	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.1881
Ubiquitin conjugating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.414
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36163
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6148
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47812
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64242
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08533
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987681
PMC5076770__F2	PFOCR Pathway Figure Associations 2024	1.0	null
STAT1_KD_GDS4754_159_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41384
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67919
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851441
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286736
regulation of canonical Wnt signaling pathway	GO Biological Process Annotations 2025	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67985
NUDT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16092
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979352
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934273
DYNLL1	Pathway Commons Protein-Protein Interactions	1.0	null
2793_EXOSC6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.67838
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40255
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292243
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20931
crystal	GeneRIF Biological Term Annotations	1.0	null
SARS-dORF6_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.20201
hsa-miR-651	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43145
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856901
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03937
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW1710	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40383
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.829246
CCK81	DepMap CRISPR Gene Dependency	1.0	2.74969
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PA-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22365
ATP5PB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82158
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827018
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88053
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Quiflapon	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
9886_XAB2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.02952
RCCFG2	DepMap CRISPR Gene Dependency	1.0	4.04728
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
mp10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-11A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95754
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22838
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926946
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70493
PMC9438347__F14	PFOCR Pathway Figure Associations 2024	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55241
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85637
7657_SARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.662138
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.899336
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13975
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.039259
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13033
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.41409
hsa-miR-203	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00745
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27232
OVSAHO	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51197
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSC 23766	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09226
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965709
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intrinsic apoptotic signaling pathway in response to oxidative stress	GO Biological Process Annotations 2025	1.0	null
EW8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82119
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44868
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47491
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77747
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27796
U138MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87868
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8333
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60291
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42956
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3411-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9013323-13577_2022_685_MOESM7_ESM.docx-2-KLF5_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842715
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Guanethidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.71
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.353
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32684
TIA1_KO_GSE54418_262_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3134	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856971
GSE151782_3_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886618
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.53437
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.968115
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957776
Perturb_2019_KO_Parp1_SRP243891	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.90536
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.763869
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6FZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0997
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61517
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
doxorubicin_homo sapiens_gpl550_gds847	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.58708
Perturb_13914_KD_SLC45A4_SRP173763	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.26191
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825294
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9167
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5013
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944718
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.1622
xtk1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.698
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12042
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00966
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849797
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.837416
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17747
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06389
bewo	HPA Cell Line Gene Expression Profiles	1.0	1.14691
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995828
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84451
hsa-miR-4427	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02588
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.93069
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.938232
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.02915
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140322_3_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52711
TAL1	ENCODE Transcription Factor Targets	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53258
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00975
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21669
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14478
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.974167
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06842
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21359
GATA1	ENCODE Transcription Factor Targets	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961678
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941524
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01732
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.500019
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27098
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-4324	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22715
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20636
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.38505
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.826974
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11762
BT483	CCLE Cell Line Gene CNV Profiles	1.0	1.50824
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53234
NCI-H1792	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.19049
Perturb_2376_KD_Cdk8_SRP292215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.0222
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-8693-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.594707
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.55865
Perturb_17765_KO_Prdm16_SRP238935	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.93263
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310599
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.07487
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963109
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.18034
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19277
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
ZINC8945	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
HS695T_SKIN	CCLE Cell Line Proteomics	1.0	2.43365
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.59195
Bromopyruvic acid	DeepCoverMOA Drug Mechanisms of Action	1.0	0.62
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20598
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02813
Perturb_10276_KO_31O21Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.38521
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55087
Adrenocortical carcinoma_ACC_TCGA-OR-A5KW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03566
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11162
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228628
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.67019
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283304
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20886
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00151
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225668
POLR2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08992
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.981974
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61123
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864127
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05513
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
NB6	DepMap CRISPR Gene Dependency	1.0	2.84081
Intramuscular adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
Perturb_8595_KO_Scn1a_SRP311872	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32512
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998652
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4945
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48667
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30167
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6065
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26588
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37169
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976706
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BNIP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38544
small intestine	HPA Tissue Gene Expression Profiles	1.0	1.12911
Leber congenital amaurosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22738
Nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
TE6	CCLE Cell Line Gene CNV Profiles	1.0	1.99234
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09742
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91628
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04388
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7877185__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05909
hsa-miR-579	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHEMBL569227	DeepCoverMOA Drug Mechanisms of Action	1.0	0.41
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.11158
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5035
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.57167
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
GSE133683_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.976
structure	GeneRIF Biological Term Annotations	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37099
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13914
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00109
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EB-66-IH06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244867
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LCL161	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.937306
NCI-H2804	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.40396
RAB35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12774
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42012
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.5513
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39947
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUIT2	DepMap CRISPR Gene Dependency	1.0	2.1877
MELJUSO	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75074
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	186.044
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930366
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0041
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870965
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1254
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25366
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05484
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54623
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02088
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15071
PMC5451507__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04662
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.72837
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSKIP domain	InterPro Predicted Protein Domain Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11663
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14979
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950941
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1254
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.911159
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88053
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.934843
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13637
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09483
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05295
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ovary	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.97989
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03829
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42262
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928644
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21811
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339918
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4034
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841848
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39587
Glufosinate	DeepCoverMOA Drug Mechanisms of Action	1.0	0.66
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850354
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3415
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921992
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01734
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948553
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NUGC-4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.40633
Integral component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69244
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PRKAR1A	Pathway Commons Protein-Protein Interactions	1.0	null
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29499
TMK-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.35122
respiratory failure	MGI Mouse Phenotype Associations 2023	1.0	null
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02779
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.50878
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240896,GSE240899_10_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57857
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.861582
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6511
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.646513
KM12	CCLE Cell Line Gene Expression Profiles	1.0	1.54883
AXIN2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960975
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850421
ZR751	CCLE Cell Line Gene Expression Profiles	1.0	1.5792
regulation of protein kinase activity	GO Biological Process Annotations 2023	1.0	null
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00745
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0797
HCC38_BREAST	CCLE Cell Line Proteomics	1.0	2.37851
regulation of signal transduction	GO Biological Process Annotations 2023	1.0	null
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51156
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07948
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.41306
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6879-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891282
positive regulation of Wnt signaling pathway	GO Biological Process Annotations 2023	1.0	null
hsa-miR-4539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33959
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949744
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14034
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60633
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-398	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.72488
CLDN18_KO_GDS4961_28_mouse_whole lung tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5547
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90943
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21186
PMC8931289__F9	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56189
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843745
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32254
network	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17194
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71591
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXN4+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57577
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16659
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88464
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216936
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.27683
PMC7324530__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38242
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4348
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of protein kinase activity	GO Biological Process Annotations 2025	1.0	null
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92721
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917612
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSK3B	Hub Proteins Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10238
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_13448_OE|KD_PAX2|PTEN_SRP279768	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.61028
Perturb_16920_KD_H19_SRP151268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.80935
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88083
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20598
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72359
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
duodenum	HPA Tissue Gene Expression Profiles	1.0	0.865002
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
JL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58435
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Perturb_5264_OE_Dcaf11_SRP328699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64018
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16737_KO_Rag2/Il2rg/Notch3_SRP220745	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.63909
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41248
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02238
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5732
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04388
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828078
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
16715129-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
GATA3-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5337147__F2a	PFOCR Pathway Figure Associations 2023	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926716
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02897
Uterine Carcinosarcoma_UCS_TCGA-NF-A5CP-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21929
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01236
EJM	CCLE Cell Line Gene CNV Profiles	1.0	2.59589
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.99062
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4693-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19235837-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03263
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	2.04915
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04089
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02169
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66292
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878122
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08849
hel	HPA Cell Line Gene Expression Profiles	-1.0	-1.79307
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00975
r5 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0506
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80149
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.30993
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10509
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6459
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03116
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3219
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05751
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881829
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IM-95	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.03216
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11211
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03794
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983869
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3284
LOUNH91	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53899
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.66973
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4711_KO_Sox9_ERP109172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.4553
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1254
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88947
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27997
Intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18355
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01918
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34689
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06132
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22458
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38153
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47922
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47497
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880292
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963217
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050829
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859314
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23795
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5809
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12595
Perturb_1223_KD_ACIN1_SRP033393	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.21801
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04393
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.874296
hsa-miR-3128	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_13761_KO_Hotair_SRP026100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97547
NCI-H226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14592
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.719
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87925
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63201
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924918
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62221
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15738
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867504
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855627
MADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9177
MORF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34164
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.782
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.25594
hsa-miR-4637	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FD-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU245	CCLE Cell Line Gene Expression Profiles	1.0	2.00711
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13282
L363	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53734
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22998
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045814
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.36205
GTEX-SNOS-0626-SM-4DM5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912794
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46945
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_12129_KO_IslandsH/Lipsi/Sfaktiria_SRP136181	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.78536
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24712
embryo	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252371
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05617
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.00444
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30148
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883978
GSE210101,GSE210114_7_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864608
PMC8144425-41467_2021_22930_MOESM4_ESM.xlsx-Fig_5c_Post-Viremia-ATF5_ATF5	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050725
GTEX-XUZC-1026-SM-4BOPY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24474
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.7752
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866418
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NH-12	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.21733
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23172
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cyanosis	MGI Mouse Phenotype Associations 2023	1.0	null
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74408
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890103
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5630-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937184
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86788
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24125
PMC8516342__F8	PFOCR Pathway Figure Associations 2024	1.0	null
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13279
Perturb_11720_KD_Plodip2_SRP303067	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.06639
SAP30	ENCODE Transcription Factor Targets	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Conotruncal heart defects (inherited effects)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286288
Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2345
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25439
Sarcoma_SARC_TCGA-DX-A1L0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17673513-Table1	GeneSigDB Published Gene Signatures	1.0	null
SF295_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.81938
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946509
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04558
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60358
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228123
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33444
USF2_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06682
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0456
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cd4.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13989
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13327
POLR2A	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3592
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60827
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.52264
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972971
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12859
GSK3A	Pathway Commons Protein-Protein Interactions	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76978
Plasma membrane respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08205
Perturb_16697_KO_70L02Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.89663
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9005
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03483
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52642
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.215761
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918889
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUDHL4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64158
Myeloid Leukemia	DisGeNET Gene-Disease Associations	1.0	null
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47609
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	75.3306
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13958
N6022	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
NEXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72668
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831567
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464702
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844983
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06066
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08782
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21042
cell part	GO Cellular Component Annotations 2015	1.0	null
APC	Pathway Commons Protein-Protein Interactions	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5762
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4447
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04455
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03555
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0653
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308664
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21978
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.94741
Prostate adenocarcinoma_PRAD_TCGA-VP-A87J-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6148
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.72251
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00239
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99698
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.05291
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24281
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16872
beta-catenin-TCF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67799
Perturb_3470_KO_Gsa_SRP045496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.009
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33516
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18036
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907821
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26426
hsa-miR-548aa	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34748
GTEX-XBED-1526-SM-4AT5W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11379
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31661
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-364-ZNF775_ZNF775	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13501
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846832
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839437
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02471
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15235_KO_Scl/Tal1_SRP179031	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.53749
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKM-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
LU-99A	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.20113
BAG3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02414
kinase binding	GO Molecular Function Annotations 2023	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.34299
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22603
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93938
EB-09-JJ93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248423
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847288
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08778
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25186
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872002
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68644
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00147
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89356
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1391
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825881
WM1799_SKIN	CCLE Cell Line Proteomics	1.0	4.19688
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.6236
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42885
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1823_KO_Ifnar_SRP371304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.31635
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56956
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8850648-Table11.xlsx-KS-DEGs_Vs_Liu_et_al_2019-Are_listed_the_239_DEGs_in_common_between_the_current_study_and_the_published_RNAseq_data_of_NRF1_overexpression_in_human_cells_Liu_et_al_2019_NRF1	Rummagene Transcription Factor Associations 2026	1.0	null
NCM-460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.09268
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01307
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.66619
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5076770__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7342
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.906693
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69331
RABEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33669
UBTF	ENCODE Transcription Factor Targets	1.0	null
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0363
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01317
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90243
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04424
positive regulation of canonical Wnt signaling pathway	GO Biological Process Annotations 2025	1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41489
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89044
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843654
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926309
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	3.05317
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01632
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39604
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03855
autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.388166
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZNF723	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2082
Perturb_4616_KD_Rfx1_SRP231452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.7533
AGAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22281
fluorouracil_homo sapiens_gpl550_gds847	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0691
PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16307
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53132
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUIT2	CCLE Cell Line Gene Expression Profiles	1.0	1.38841
EXT2	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68175
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8494
Small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.461
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19289
isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21538
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86044
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
GSE158285_0_v_1_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10111
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38007
hsa-miR-320a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.830397
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
ES8	DepMap CRISPR Gene Dependency	1.0	3.87321
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32715
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3622
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44427
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.76967
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.899657
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03263
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11221
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22838
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06349
Atglistatin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8267409__F1	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRUNE	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86032
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07572
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853831
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04359
SNU175	CCLE Cell Line Gene Expression Profiles	1.0	2.78067
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13554
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08909
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35879
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13161
Perturb_10310_KO_3110043O21Rik_ERP013119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.6739
Perturb_13624_KO_Tet2_SRP201229	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.09403
NCI-H520	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.91076
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906005
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20349
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22171
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15188
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.909071
CUX1	ENCODE Transcription Factor Targets	1.0	null
PMC9013323-13577_2022_685_MOESM7_ESM.docx-5-FOXN3_FOXN3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31569
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34023
Glycogen synthase kinase-3 (gsk-3) signaling regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08451
nucleus	GO Cellular Component Annotations 2023	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	3.03724
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43841
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7064
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE143782_7_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44431
GTEX-QCQG-1426-SM-48U22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867423
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24131
Ripasudil	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834948
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848659
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03016
PDK1_knockout_80_GSE26290	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.85509
colon	HPA Tissue Gene Expression Profiles	1.0	1.23825
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05483
KAT2A	ENCODE Transcription Factor Targets	1.0	null
Perturb_16484_KO_Ikk2_SRP131881	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.158
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911385
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894206
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07835
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU620	CCLE Cell Line Gene Expression Profiles	1.0	1.44122
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13058
TP53	ChEA Transcription Factor Targets	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65652
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.36062
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05254
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4348
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05458
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42061
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34658
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.926435
Perturb_8576_OE_Xbp1_SRP288940	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.61084
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0267
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83091
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3897
me180	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
T3M4	DepMap CRISPR Gene Dependency	1.0	2.14809
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4117-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSU	CCLE Cell Line Gene Expression Profiles	1.0	1.3764
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.854265
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4849
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99222
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51407
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11574
vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-NFKB1_mod_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.97726
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
2-PMPA	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18814
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947879
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41539
nuclear part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
regulation of protein kinase activity	GO Biological Process Annotations 2025	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20349
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871771
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11796
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38385
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20341
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16872
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040636
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65667
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06135
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22947
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	1.0	3.27914
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22983
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0932
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02341
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32034
GSE143782_6_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.004
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4892
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863815
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18302
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842649
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52287
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	1.0	1.42171
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00269
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02276
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30941
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41835
PC14	CCLE Cell Line Gene CNV Profiles	-1.0	-2.83118
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0425
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75452
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07766
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5895
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.29054
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11966
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
16318415-TableS1	GeneSigDB Published Gene Signatures	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8526
peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.348981
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.57
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60959
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-dORF6_24Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.93056
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15555
mRNA_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
hsa-miR-636	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959011
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5108588__F8	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47189
protein kinase regulator activity	GO Molecular Function Annotations 2025	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888505
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04008
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871887
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2ES-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6125
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CV-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4664-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1192
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943312
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.967191
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.92427
4955_MED4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.536849
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63302
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69112
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839021
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49873
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NR2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8813
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
protein kinase A regulatory subunit binding	GO Molecular Function Annotations 2025	1.0	null
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58332
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43068
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919863
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898544
OCUM1	CCLE Cell Line Gene Expression Profiles	1.0	1.59023
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.869708
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.493155
connecting stalk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Megakaryocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
outer SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85135
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0722
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-19b	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.27142
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79308
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18752
Olodaterol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39695
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77965
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20563
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88053
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SM-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7919-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19759
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826408
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F3-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8032
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18487
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497663
CAL62	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97675
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18076
gskip	GeneRIF Biological Term Annotations	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832298
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.982143
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3399
TUHR4TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43842
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47107
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.767671
suggests	GeneRIF Biological Term Annotations	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972559
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3565
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.194865
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42137
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88053
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16612
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29307
H3K36me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11626
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.922768
hsa-miR-3121-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-39-ENSG00000151612_ZNF827	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERBB3:ERBB2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.74
OVCAR5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49897
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.167
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.838508
NB7	DepMap CRISPR Gene Dependency	1.0	2.60305
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25829
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06075
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13672
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965776
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02597
TD-69-UA90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317824
LN443	CCLE Cell Line Gene CNV Profiles	1.0	1.36702
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased vocalization	MGI Mouse Phenotype Associations 2023	1.0	null
PMC7877185__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886864
U138MG	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06378
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923081
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3919
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31579
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66566
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5708
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82695
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01995
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43545
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85261
CORL47_LUNG	CCLE Cell Line Proteomics	1.0	3.27171
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31131
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.64594
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42885
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12908
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13285
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6627
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.20349
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.885779
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363232
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05326
protein kinase binding	GO Molecular Function Annotations 2023	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Moxonidine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16276
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74326
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80576
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1842
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2059
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.877567
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3211
chr14_96346483_A_C_b38	GTEx eQTL 2025	1.0	1.86731
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83122
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21967
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30867
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91702
OCUM-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.02556
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
GATA2	ENCODE Transcription Factor Targets	1.0	null
Perturb_16704_KO_Dock11_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.10128
CA-48-JF51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249835
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17685
kinase inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050829
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246257
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15503
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10847
hsa-miR-646	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23936
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930026
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927447
PMC8563805-41598_2021_858_MOESM2_ESM.xlsx-Supplementary_Info_6-Gene_List_6_The_list_of_human_orthologs_of_the_downregulated_fly_DEGs_identified_from_TRAP_control_vs_PARIS_wild_type_comparison_ZNF746	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851469
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09786
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05428
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
17683608-TableS3	GeneSigDB Published Gene Signatures	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	10.897
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_down_VENN-1175_elements_included_exclusively_in_HIF1_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72346
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8876_KD_ABCB6_SRP309466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.12056
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07608
Myelodysplastic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-39-ZNF827_ZNF827	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36685
inferior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.928302
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59954
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40386
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42885
umbilical artery	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SMARCA4-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8370976-41467_2021_24932_MOESM6_ESM.xlsx-Annotation-Supplementary_Data_4_GO_and_metascape_analysis_of_the_genes_downregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.1615
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60657
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7651-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2515
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21739
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE204832_0_v_1_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04457
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53612
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33179
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41023
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03725
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03255
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05728
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00664
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82458
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5521-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15594_KD_PPARG_SRP049523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Golgi apparatus	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_5W_vs_LS_5W-gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7989
Lung adenocarcinoma_LUAD_TCGA-05-4390-01A-02R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-BatSRBD_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.49459
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040077
ACOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00529
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79091
negative regulation of protein kinase activity	GO Biological Process Annotations 2023	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3957
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848358
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14072
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.832464
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.46127
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48525
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47903
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null