association dataset threshold value standardized value Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059137 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25215 extracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.7908 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2981 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52539 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.24877 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.879804 Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.7196 NCIH1573 DepMap CRISPR Gene Dependency 1.0 3.00207 hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1799 ursodeoxycholic acid_mus musculus_gpl8321_gse21266 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null hsa-miR-4720-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6019-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neoplasms CTD Gene-Disease Associations 1.0 2.23712 methylprednisolone_rattus norvegicus_gpl341_gds972 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07162 Biological oxidations Reactome Pathways 2024 1.0 null RVH421 CCLE Cell Line Gene CNV Profiles -1.0 -1.32181 Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63569 Urinary Bladder Neoplasms CTD Gene-Disease Associations 1.0 1.69597 KLE DepMap CRISPR Gene Dependency 1.0 4.43733 Hemoglobin levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.0 cafestol CTD Gene-Chemical Interactions 1.0 null ZFX_KO_GDS2718_150_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058701 orbital frontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.863077 LS1034 DepMap CRISPR Gene Dependency 1.0 3.62244 S-(Formylmethyl)glutathione HMDB Metabolites of Enzymes 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null extracellular vesicle GO Cellular Component Annotations 2015 1.0 null TCCSUP COSMIC Cell Line Gene Mutation Profiles 1.0 null OTX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5315 PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1 Rummagene Transcription Factor Associations 2026 1.0 null GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07162 NCIH661 CCLE Cell Line Gene CNV Profiles 1.0 1.96307 respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053688 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.564 sulfur compound metabolic process GO Biological Process Annotations 2015 1.0 null Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.267 MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.541 TAL1 ENCODE Transcription Factor Targets 1.0 null Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 55.135 K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 2.63801 ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7016 HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6904 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.24348 renal GAD High Level Gene-Disease Associations 1.0 0.293278 GATA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5634 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07148 Pyruvaldehyde CTD Gene-Chemical Interactions 1.0 null CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null L363 DepMap CRISPR Gene Dependency 1.0 2.04195 OSC19 DepMap CRISPR Gene Dependency 1.0 3.06336 primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34582 cuneus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.77185 NFE2L2_Mutation_GDS4498_597_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SMAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74006 TP63 ChEA Transcription Factor Targets 1.0 null amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02836 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25624 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4477 globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12778 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.357 Defective UGT1A4 causes hyperbilirubinemia Reactome Pathways 2014 1.0 null nfe2l2_2383093_whole_skin_gof_mouse_gpl1261_gse35160 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.229104 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13648 Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 2.39964 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null HNF4alpha_KO_GDS1915_173_mouse_Small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Cholestasis, Intrahepatic CTD Gene-Disease Associations 1.0 1.03939 Blood Coagulation Disorders CTD Gene-Disease Associations 1.0 1.2596 Liver Neoplasms CTD Gene-Disease Associations 1.0 2.51251 SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.919086 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02675 Gap junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.375 Oxycodone CTD Gene-Chemical Interactions 1.0 null MFE280 DepMap CRISPR Gene Dependency 1.0 4.72401 supramarginal gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.838975 Cholestasis CTD Gene-Disease Associations 1.0 1.35328 Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null S-(2-Chloroacetyl)glutathione HMDB Metabolites of Enzymes 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.841993 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.850853 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.643573 Cardiovascular Diseases CTD Gene-Disease Associations 1.0 1.23328 colorectal cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.490619 DB DepMap CRISPR Gene Dependency 1.0 4.39107 Hyperplasia CTD Gene-Disease Associations 1.0 2.30025 posterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50456 orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.931703 cellular metabolic process GO Biological Process Annotations 2015 1.0 null PMC8505648__F3 PFOCR Pathway Figure Associations 2024 1.0 null Liver Failure, Acute CTD Gene-Disease Associations 1.0 1.37705 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AB-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1539 ZBTB32 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1207 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.00614 CLPP_KO_GDS4791_541_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.4369 nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.2207 PRDM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32539 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9393 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2607 Heart - Left Ventricle GTEx Tissue Gene Expression Profiles 2023 1.0 4.89165 Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PADI4-21655091-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Mental Disorders CTD Gene-Disease Associations 1.0 1.03493 Olig2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.8727 feather TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.195437 SJSA1_BONE CCLE Cell Line Proteomics 1.0 4.79418 SP1 ENCODE Transcription Factor Targets 1.0 null COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65607 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1737 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38723 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.098266 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35843 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6824-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYB-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8430-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEC2 CCLE Cell Line Gene CNV Profiles -1.0 -1.48518 SCC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null GP5D DepMap CRISPR Gene Dependency 1.0 3.9979 copy GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76236 producing GeneRIF Biological Term Annotations 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16508 SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.955272 chronic myeloid leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.169218 DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2158 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059584 Prostate adenocarcinoma_PRAD_TCGA-G9-6370-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.25 Prostatic Neoplasms CTD Gene-Disease Associations 1.0 1.11741 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.340019 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59274 Glycosuria CTD Gene-Disease Associations 1.0 1.08266 Spz1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.3333 Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hydrogen Ion HMDB Metabolites of Enzymes 1.0 null RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8133 Pathways in cancer KEGG Pathways 2026 1.0 null Mammary Neoplasms, Animal CTD Gene-Disease Associations 1.0 1.2352 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.6108 ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Butylated Hydroxyanisole CTD Gene-Chemical Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-FC-7708-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.068 HT1376 DepMap CRISPR Gene Dependency 1.0 4.25446 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null colonic adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.540188 Hemorrhage CTD Gene-Disease Associations 1.0 1.56828 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Lymphatic Diseases CTD Gene-Disease Associations 1.0 1.01739 S-(1,2-Dichlorovinyl)glutathione HMDB Metabolites of Enzymes 1.0 null M07E DepMap CRISPR Gene Dependency 1.0 2.35737 AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830536 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12354 posteroventral (inferior) parietal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.916107 blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066046 colorectal cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.162436 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.2923 MELHO DepMap CRISPR Gene Dependency 1.0 2.08706 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10285 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62279 CLPP_KO_GSE40207_394_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null A-CA-04-2009(H1N1)_12Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.37994 SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3829 Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 Metabolism of xenobiotics by cytochrome P450 KEGG Pathways 2026 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.279011 MET_knockout_251_GDS3148 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.20787 HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.421 NCI-H358 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.87 hek-293t cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.358546 Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null agranular insular cortex (area Iag) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.834946 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6053 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19095 colon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.309335 ochratoxin A CTD Gene-Chemical Interactions 1.0 null mature GeneRIF Biological Term Annotations 1.0 null A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65279 mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37742 Parkinson Disease CTD Gene-Disease Associations 1.0 1.05685 NCIH2286 CCLE Cell Line Gene CNV Profiles -1.0 -1.7014 IM9 DepMap CRISPR Gene Dependency 1.0 5.71923 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SS-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PATU8988T DepMap CRISPR Gene Dependency 1.0 3.39192 leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07594 NCI-H1155 COSMIC Cell Line Gene Mutation Profiles 1.0 null gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.229024 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TGFBR1_activemutant_291_GSE14523 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.72536 Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0345 Defective UGT1A1 causes hyperbilirubinemia Reactome Pathways 2014 1.0 null MYC-20876797-MEDULLOBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null short insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08404 SCD_KO_GSE24243_46_mouse_Skin (8-9 wk) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08873 large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.30342 Jaundice CTD Gene-Disease Associations 1.0 1.13211 quercetin 3-arabinopyranoside CTD Gene-Chemical Interactions 1.0 null Dizziness CTD Gene-Disease Associations 1.0 1.09716 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.696 Proteinuria CTD Gene-Disease Associations 1.0 1.70886 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Aryl hydrocarbon receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.953 urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.320227 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.992008 anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.910476 ZNF587 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0891 red nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15689 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-11A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE236437_2_v_3_aldosterone_human RummaGEO Drug Perturbation Signatures -1.0 null KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00569 Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.371 Glutathione HMDB Metabolites of Enzymes 1.0 null EN2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8683 GATA1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CERS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17536 cellular_component GO Cellular Component Annotations 2015 1.0 null sw-480 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.375743 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23176 Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Reactome Pathways 2014 1.0 null cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.164089 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.518465 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.424765 midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36981 TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5314 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1 Rummagene Transcription Factor Associations 2026 1.0 null VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15975 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38215 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040661 Prenatal Injuries CTD Gene-Disease Associations 1.0 1.13963 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055765 XBP1_OE_GDS5065_273_mouse_F424a adipocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09428 leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077479 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20832 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.3156 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null piriform cortex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10886 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11362 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene HMDB Metabolites of Enzymes 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.990194 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30656 OCT4-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3321 anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40921 Hypothyroidism CTD Gene-Disease Associations 1.0 1.0353 enzyme GeneRIF Biological Term Annotations 1.0 null primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.17289 GATA-1_KD_GDS1245_81_mouse_megakaryocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5452 EBC-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.707 inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.68424 CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pleura TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.19632 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12816 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.8751 TT CCLE Cell Line Gene CNV Profiles 1.0 2.17103 CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.58806 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2614 Phase II conjugation Reactome Pathways 2014 1.0 null CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7848 PK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.61207 RXRA ENCODE Transcription Factor Targets 1.0 null hep-g2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.316224 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hyperglycemia CTD Gene-Disease Associations 1.0 1.59896 adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.544549 SARS-CoV_72Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.68204 OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895491 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.4008 KURAMOCHI CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 fusiform gyrus, left, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.898832 CLPP_KO_GSE40207_382_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61576 Stomach Ulcer CTD Gene-Disease Associations 1.0 1.26052 Thyroid Neoplasms CTD Gene-Disease Associations 1.0 1.46015 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.858158 J82 DepMap CRISPR Gene Dependency 1.0 3.09202 HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9692 principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0522 18614019-TableS4d GeneSigDB Published Gene Signatures 1.0 null MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45827 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2758 metabolism of xenobiotics by cytochrome p450 KEGG Pathways 1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.241746 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.19 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03035 extracellular region part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.932 Cognition HuGE Navigator Gene-Phenotype Associations 1.0 null NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71485 KYSE150 CCLE Cell Line Gene CNV Profiles 1.0 1.52076 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1897 CCLE Cell Line Gene CNV Profiles -1.0 -1.75786 MAX ENCODE Transcription Factor Targets 1.0 null Drug Hypersensitivity CTD Gene-Disease Associations 1.0 1.3103 testis HPA Tissue Protein Expression Profiles 1.0 0.773003 Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A498 CCLE Cell Line Gene CNV Profiles -1.0 -1.5269 CLDN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26915 Detrusor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.552 LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4502 COLO205 CCLE Cell Line Gene CNV Profiles 1.0 2.19903 bronchus HPA Tissue Protein Expression Profiles 1.0 1.0151 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3721 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.6417 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.358 COLO792 CCLE Cell Line Gene CNV Profiles -1.0 -1.9285 posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25235 Benzo[a]pyrene-4,5-oxide HMDB Metabolites of Enzymes 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13752 Glutathione S-transferase, N-terminal InterPro Predicted Protein Domain Annotations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.90867 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.979614 Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.6811 Prostate adenocarcinoma_PRAD_TCGA-FC-7961-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF4_01_339 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.89157 LHX1_NULL MUTATION - Ablation_GDS1748_748_mouse_Embryonic kidneys (from day E14.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null alitretinoin_rattus norvegicus_gpl85_gse3952 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RH28 DepMap CRISPR Gene Dependency 1.0 2.20985 Nausea CTD Gene-Disease Associations 1.0 1.17629 SCH COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08916 CAL148 CCLE Cell Line Gene CNV Profiles 1.0 1.74922 POLR2A ENCODE Transcription Factor Targets 1.0 null Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7171 inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29149 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12354 large intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.255234 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.838062 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.0221 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0396 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01538 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.40471 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01383 SP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.76772 GSE86021_0_v_1_crenolanib_human RummaGEO Drug Perturbation Signatures 1.0 null A2058_SKIN CCLE Cell Line Proteomics 1.0 2.52241 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16373 Memory Disorders CTD Gene-Disease Associations 1.0 1.70533 colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.303781 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5174 CAVIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84269 SRF JASPAR Predicted Transcription Factor Targets 1.0 null 647-V COSMIC Cell Line Gene Mutation Profiles 1.0 null Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.006 NCI-SNU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.45403 Neurotoxicity Syndromes CTD Gene-Disease Associations 1.0 1.74601 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4398 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04852 Glutathione metabolism WikiPathways Pathways 2024 1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09113 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null LC1SQ DepMap CRISPR Gene Dependency 1.0 3.6022 RCCFG2 DepMap CRISPR Gene Dependency 1.0 2.08567 Hepatitis CTD Gene-Disease Associations 1.0 1.68506 SHP-77 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1907 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Metabolism Reactome Pathways 2024 1.0 null Aldophosphamide HMDB Metabolites of Enzymes 1.0 null Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Reactome Pathways 2014 1.0 null layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15517 rosiglitazone_rattus norvegicus_gpl341_liver_gds3850 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3809 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.30347 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.03072 dexamethasone_rattus norvegicus_gpl1355_gse29912 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null glutathione transferase activity GO Molecular Function Annotations 2025 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H661 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65M-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Hepa-RG cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.85 Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052226 Lung Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null Intercellular bridge COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.248 ethyl tert-butyl ether CTD Gene-Chemical Interactions 1.0 null TLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33306 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72755 2,2-Dichloroacetaldehyde HMDB Metabolites of Enzymes 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35554 Diarrhea CTD Gene-Disease Associations 1.0 1.03493 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1402 H-EMC-SS COSMIC Cell Line Gene Mutation Profiles 1.0 null NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7238 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0695 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.98682 extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3129 NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null Metapathway biotransformation(Homo sapiens) WikiPathways Pathways 2014 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.89066 EGR1 ChEA Transcription Factor Targets 1.0 null adrenal gland GTEx Tissue Gene Expression Profiles 1.0 0.981868 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.7658 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.56732 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23495 Cell Transformation, Neoplastic CTD Gene-Disease Associations 1.0 1.6593 Chloroacetyl chloride HMDB Metabolites of Enzymes 1.0 null cellular_component LOCATE Curated Protein Localization Annotations 1.0 null MYC-20876797-MEDULLOBLASTOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene HMDB Metabolites of Enzymes 1.0 null wing TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.174878 1-cyano-2-hydroxy-3-butene CTD Gene-Chemical Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DBH_KO_GDS4324_362_mouse_Embryonic heart E10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.961208 Kidney Diseases CTD Gene-Disease Associations 1.0 2.16329 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.924815 CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 HCT116 DepMap CRISPR Gene Dependency 1.0 7.23097 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.322414 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054818 Lung non-small cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.054 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.899156 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.83578 Hypertension CTD Gene-Disease Associations 1.0 2.88009 Glutathione episulfonium ion HMDB Metabolites of Enzymes 1.0 null HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13648 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -2.12421 Biological oxidations Reactome Pathways 2014 1.0 null KPL1_BREAST CCLE Cell Line Proteomics 1.0 4.45397 cytoplasm LOCATE Curated Protein Localization Annotations 1.0 null PMC10202654-mmc6.xlsx-KEGG_cancer_pathway-KEAP1-NRF_signaling_NKRF Rummagene Transcription Factor Associations 2026 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68174 Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12769 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12354 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.832489 Weight Gain CTD Gene-Disease Associations 1.0 1.17893 EGFR_drugactivation_20_GDS2146 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -3.52755 Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC ChEA Transcription Factor Targets 1.0 null Warfarin sensitivity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.31 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72467 mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.31919 colonic cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.234016 chronic myeloid leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.531089 Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 Ciliary shaft COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.587 HOXC10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4111 Glutathione metabolism KEGG Pathways 2026 1.0 null Seizures CTD Gene-Disease Associations 1.0 1.67718 Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.351 EZH2 ENCODE Transcription Factor Targets 1.0 null CLPP_KO_GDS4791_375_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7817-01B-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.3218 Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.4972 Testis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 Fever CTD Gene-Disease Associations 1.0 1.48838 NANOG-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null UACC893 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.45512 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062404 parahippocampal gyrus, right, bank of the cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03557 NP3 DepMap CRISPR Gene Dependency 1.0 3.02014 NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.34189 liver cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068502 2-(S-Glutathionyl)acetyl glutathione HMDB Metabolites of Enzymes 1.0 null Liver TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.338 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.834875 Male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2291 gastrointestinal cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.224893 LHX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7158 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064901 769P_KIDNEY CCLE Cell Line Proteomics 1.0 2.3481 Alzheimer Disease HuGE Navigator Gene-Phenotype Associations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6721 Drug-Related Side Effects and Adverse Reactions CTD Gene-Disease Associations 1.0 1.88409 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02978 KLF15_Deficiency_GDS2687_648_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-4799-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Glioblastoma CTD Gene-Disease Associations 1.0 1.13245 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13648 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4368 CLPP_KO_GSE40207_379_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null A_CA_04_2009_4dayMOI-10^6_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.2319 Obstructive sleep apnea_Hepatic Tissue_GSE1873 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.59154 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97512 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8776 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3645 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44367 Acrolein CTD Gene-Chemical Interactions 1.0 null Headache CTD Gene-Disease Associations 1.0 1.03567 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8499 Warfarin resistance DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22682 extracellular vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.057922 IZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39588 Gut TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.367 MFE296 DepMap CRISPR Gene Dependency 1.0 2.88717 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uveal melanoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.611 Benzo[a]pyrene-7,8-diol HMDB Metabolites of Enzymes 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null XPO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06451 Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9553 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20214 HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.083 PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3 Rummagene Transcription Factor Associations 2026 1.0 null spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.895207 molecular_function GO Molecular Function Annotations 2015 1.0 null Metabolism Reactome Pathways 2014 1.0 null extracellular organelle GO Cellular Component Annotations 2015 1.0 null Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.2963 Cholangiocarcinoma CTD Gene-Disease Associations 1.0 1.16799 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.286 Kidney Neoplasms CTD Gene-Disease Associations 1.0 1.1253 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null Platelet count GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.809691 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-11A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Neoplasms CTD Gene-Disease Associations 1.0 1.10803 2,3-Epoxyaflatoxin B1 HMDB Metabolites of Enzymes 1.0 null Banded collagen fibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.538 outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.961915 Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.001 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.955731 hepatoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.388158 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Metapathway biotransformation Phase I and II WikiPathways Pathways 2024 1.0 null COLO800 DepMap CRISPR Gene Dependency 1.0 4.38402 Anorexia CTD Gene-Disease Associations 1.0 1.10282 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27556 Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.6154 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.35852 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9474 cell part LOCATE Curated Protein Localization Annotations 1.0 null posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.89865 T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.817239 CLPP_KO_GDS4791_539_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null pi1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.682 Estrogen metabolism(Mus musculus) WikiPathways Pathways 2014 1.0 null VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0985 RH30_SOFT_TISSUE CCLE Cell Line Proteomics 1.0 3.43149 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2227 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6042 Gastrointestinal Diseases CTD Gene-Disease Associations 1.0 1.3903 TAL1_megakaryocyte_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4299 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.71683 SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 1.74149 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.54587 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2074 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04059 Lung Neoplasms CTD Gene-Disease Associations 1.0 2.05821 Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.265 mediodorsal nucleus of thalamus_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.925917 extracellular vesicular exosome GO Cellular Component Annotations 2015 1.0 null gata1_15895080_e12dot5_liver_megakaryocyte_lof_mouse_gpl1261_gds1316 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.838146 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.353 metabolic process GO Biological Process Annotations 2015 1.0 null transferase activity, transferring alkyl or aryl (other than methyl) groups GO Molecular Function Annotations 2015 1.0 null 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.39185 BSX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9562 ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7767 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null aflatoxin B1-2,3-oxide CTD Gene-Chemical Interactions 1.0 null 2-(S-Glutathionyl)acetyl chloride HMDB Metabolites of Enzymes 1.0 null Fibrosis CTD Gene-Disease Associations 1.0 1.9841 SNU46 CCLE Cell Line Gene CNV Profiles 1.0 1.42701 Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUHR14TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.68606 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KF-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.24245 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68174 biological_process GO Biological Process Annotations 2015 1.0 null CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2916 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.044 SUM1315MO2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.11544 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5217 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.913992 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5965 temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.961415 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24775 1,1-Dichloroethylene epoxide HMDB Metabolites of Enzymes 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.843008 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43114 Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 121.65 Metabolic disorders of biological oxidation enzymes Reactome Pathways 2014 1.0 null PBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3333 Senile cataract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.008 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.941574 facial motor nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35382 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7481 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7653 peptide metabolic process GO Biological Process Annotations 2015 1.0 null RERFGC1B DepMap CRISPR Gene Dependency 1.0 2.15618 Oligospermia CTD Gene-Disease Associations 1.0 1.40787 Insulin Resistance CTD Gene-Disease Associations 1.0 1.13381 Liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.031 TCEAL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58548 JHUEM3 CCLE Cell Line Gene CNV Profiles 1.0 1.52459 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1029 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19875 SNU119_OVARY CCLE Cell Line Proteomics 1.0 4.43908 neurological GAD High Level Gene-Disease Associations 1.0 0.293278 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13648 HCC3153 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.941503 Type 2 diabetes mellitus_Renal Tissue_GSE642 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.00026 nicotine_mus musculus_gpl1261_gse31004 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H441 COSMIC Cell Line Gene Mutation Profiles 1.0 null SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55294 parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42403 Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Reactome Pathways 2014 1.0 null Hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.931952 posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18211 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26578 Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.182 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35718 1-Nitronaphthalene-5,6-oxide HMDB Metabolites of Enzymes 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73F-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hemoglobinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.047 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18967 extracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.292 CLPP_KO_GDS4791_106_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.851768 Pain CTD Gene-Disease Associations 1.0 1.02896 SW872 COSMIC Cell Line Gene Mutation Profiles 1.0 null a11 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.418 RAD21 ENCODE Transcription Factor Targets 1.0 null ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.412 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.59564 PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null SKNSH DepMap CRISPR Gene Dependency 1.0 4.39122 MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1479 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.587 TIE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26126 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.7104 Brain cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.073 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3482 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.02 HOXB8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.036 IZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.846061 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9172 NCIH1568_LUNG CCLE Cell Line Proteomics 1.0 3.34626 cell part LOCATE Predicted Protein Localization Annotations 1.0 null Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.263 PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4331 Edema CTD Gene-Disease Associations 1.0 1.80586 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.636 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.924747 Kidney Failure, Chronic CTD Gene-Disease Associations 1.0 1.25432 Cancer pathways WikiPathways Pathways 2024 1.0 null hepatoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.246124 Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null Hemolysis CTD Gene-Disease Associations 1.0 1.2818 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SOX14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6479 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.4334 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.6526 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 90.4766 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1199 Carcinoma CTD Gene-Disease Associations 1.0 1.2944 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.352227 HS729 CCLE Cell Line Gene CNV Profiles -1.0 -1.37319 HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8744 alitretinoin_rattus norvegicus_gpl85_liver b_gds2385 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HOXB7_01_170 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.39755 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.4557 single GeneRIF Biological Term Annotations 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31107 Melphalan CTD Gene-Chemical Interactions 1.0 null organonitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05269 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1048 SUDHL8 CCLE Cell Line Gene CNV Profiles 1.0 1.42517 ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE239844_11_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5089 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4833 Adenoma, Liver Cell CTD Gene-Disease Associations 1.0 1.27502 HSD17B4_KO_GDS3468_503_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MOGGUVW DepMap CRISPR Gene Dependency 1.0 3.78511 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3565 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60502 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40183 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.23022 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11291 SARS-BatSRBD_60Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.51254 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4458 SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.67362 organelle GO Cellular Component Annotations 2015 1.0 null H3K27me3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PADI4-21655091-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene HMDB Metabolites of Enzymes 1.0 null Hepatocellular carcinoma KEGG Pathways 2026 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.89029 HSC3 CCLE Cell Line Gene CNV Profiles 1.0 2.70696 496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 17.5032 SW579 DepMap CRISPR Gene Dependency 1.0 2.16718 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.272 HSC-3 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41P-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PC-14 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.579 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.83413 NIHOVCAR3 DepMap CRISPR Gene Dependency 1.0 7.70207 NCIH1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.45501 Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.926331 H3K27me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.18448 troglitazone_rattus norvegicus_gpl341_liver_gds3850 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5508-01A-02R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.438356 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040523 WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19429 Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.300533 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.553 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24775 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.967 RH41 CCLE Cell Line Gene CNV Profiles -1.0 -1.41935 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.16342 PDX1_KO_GDS4348_360_mouse_Proximal small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1325 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Nervous System Diseases CTD Gene-Disease Associations 1.0 1.58842 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.62445 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.49557 processed GeneRIF Biological Term Annotations 1.0 null PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR Rummagene Transcription Factor Associations 2026 1.0 null Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Reactome Pathways 2014 1.0 null FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0569 NRF2 pathway WikiPathways Pathways 2024 1.0 null CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.986475 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28279 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null PHGDH_KO_GDS2874_125_mouse_embryonic head tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Myocardial Infarction CTD Gene-Disease Associations 1.0 1.03084 Bromide HMDB Metabolites of Enzymes 1.0 null Hearing Loss CTD Gene-Disease Associations 1.0 1.02896 OCIM2 DepMap CRISPR Gene Dependency 1.0 2.08139 15860665-Table1 GeneSigDB Published Gene Signatures 1.0 null PMC8725436-12864_2021_8226_MOESM3_ESM.xlsx-Sheet1-Table_S3_Target_molecules_of_NFE2L2_and_their_directional_changes_in_the_RNAseq_dataset_from_fasted_vs_12hrpf_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 127.835 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5765 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00596 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89285 NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9396 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.50335 SW480_LARGE_INTESTINE CCLE Cell Line Proteomics 1.0 4.79282 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8283 Hoxc13_OE_GDS1890_174_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null furan CTD Gene-Chemical Interactions 1.0 null Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.919914 PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-TFAP2C_TFAP2C Rummagene Transcription Factor Associations 2026 1.0 null LHX1_NULL MUTATION - Ablation_GDS1748_749_mouse_Embryonic kidneys (from day E18.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GATA1_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 2-Bromoacetaldehyde HMDB Metabolites of Enzymes 1.0 null TFAP2C-20629094-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Vomiting CTD Gene-Disease Associations 1.0 1.0189 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54943 feather vane TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.59405 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.91266 FIH_Deficiency_GDS3769_511_mouse_Immortalized embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Abnormalities, Drug-Induced CTD Gene-Disease Associations 1.0 1.44463 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.546 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV5::HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6955 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6011 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08963 posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04508 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6809 Lung carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.054 medial geniculate complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06322 S1P_Deficiency_GDS3654_521_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5554 Pancreatic Neoplasms CTD Gene-Disease Associations 1.0 1.13211 t30-blood-rna_female_2w MoTrPAC Rat Endurance Exercise Training -1.0 -15.6622 S-(Formylmethyl)glutathione MW Enzyme Metabolite Associations 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29966 CL11 CCLE Cell Line Gene CNV Profiles -1.0 -2.28139 TAL1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung Diseases CTD Gene-Disease Associations 1.0 1.28518 primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03129 oltipraz CTD Gene-Chemical Interactions 1.0 null increased physiological sensitivity to xenobiotic MGI Mouse Phenotype Associations 2023 1.0 null pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.38091 extracellular vesicular exosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.66237 allyl sulfide CTD Gene-Chemical Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.896863 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9611 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306083 indole-3-carbinol CTD Gene-Chemical Interactions 1.0 null Fibrillar collagen trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.601 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72834 LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.95 cSARS Bat SRBD_0Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.952228 ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9161 Anemia CTD Gene-Disease Associations 1.0 1.79254 survival GeneRIF Biological Term Annotations 1.0 null Whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 Chlorambucil CTD Gene-Chemical Interactions 1.0 null epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.08408 JUN ChEA Transcription Factor Targets 1.0 null Chemical carcinogenesis - receptor activation KEGG Pathways 2026 1.0 null U937 CCLE Cell Line Gene CNV Profiles 1.0 1.44076 H3K27me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 89.7035 Male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.377996 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.71489 ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7327 abcc4 GeneRIF Biological Term Annotations 1.0 null extracellular region part GO Cellular Component Annotations 2015 1.0 null Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.268 Pruritus CTD Gene-Disease Associations 1.0 1.11466 RXRA_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Defective GGT1 causes Glutathionuria (GLUTH) Reactome Pathways 2014 1.0 null Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.7863 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7423 Neurodegenerative Diseases CTD Gene-Disease Associations 1.0 1.40623 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 1.68791 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null KYSE70 CCLE Cell Line Gene CNV Profiles 1.0 1.77673 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6155 Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Trichloroethylene HMDB Metabolites of Enzymes 1.0 null Gonadal Disorders CTD Gene-Disease Associations 1.0 1.11325 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25419 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5316 Colonic Neoplasms CTD Gene-Disease Associations 1.0 1.3903 sinigrin CTD Gene-Chemical Interactions 1.0 null HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893236 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.93135 Glutathione metabolism(Mus musculus) WikiPathways Pathways 2014 1.0 null Bone Marrow Diseases CTD Gene-Disease Associations 1.0 1.10977 HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.402 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.881628 4-Glutathionyl cyclophosphamide HMDB Metabolites of Enzymes 1.0 null CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null COLO201 CCLE Cell Line Gene CNV Profiles 1.0 1.61422 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1419 epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071392 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9192 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.896472 colorectal adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.505887 colorectal adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.51453 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04967 SNU16 DepMap CRISPR Gene Dependency 1.0 2.60949 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basomedial nucleus (accessory basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.989569 Aflatoxin B1exo-8,9-epoxide-GSH MW Enzyme Metabolite Associations 1.0 null Fatty Liver CTD Gene-Disease Associations 1.0 2.11787 Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) Reactome Pathways 2014 1.0 null PMC5889290-koni-07-04-1412909-s001.xlsx-GSC-exo_vs_Fibro-exo_stat_sign-Gene_name_GSC Rummagene Transcription Factor Associations 2026 1.0 null OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.988864 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05964 Chemical carcinogenesis - reactive oxygen species KEGG Pathways 2026 1.0 null Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Reactome Pathways 2014 1.0 null Prostate adenocarcinoma_PRAD_TCGA-2A-A8W3-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 temporal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.926568 cSARS Bat SRBD_12Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.41919 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.944042 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1184 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.942 Immune System Diseases CTD Gene-Disease Associations 1.0 1.41721 SARS-CoV MA15_Day1-PFU-10^2_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.90704 KYSE-70 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 growth abnormality GWASdb SNP-Phenotype Associations 1.0 0.60465 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3144 lateral hypothalamic area, anterior region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.932377 cancer GAD High Level Gene-Disease Associations 1.0 0.293278 cellular modified amino acid metabolic process GO Biological Process Annotations 2015 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5581 Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.3913 SUM149PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.882278 TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1543 kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.335233 lung cancer GAD Gene-Disease Associations 1.0 null pioglitazone_rattus norvegicus_gpl341_liver_gds3850 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Heparanase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.768 H3K27me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BBm cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.818 dentate (lateral) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.15742 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924984 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6543 cSARS Bat SRBD_24Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.88514 cellular amide metabolic process GO Biological Process Annotations 2015 1.0 null primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.894838 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.929165 Glutathione metabolism(Homo sapiens) WikiPathways Pathways 2014 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31383 CBX2_KO_GDS4445_354_mouse_E11.5 XY embryonic gonads GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Metapathway biotransformation(Mus musculus) WikiPathways Pathways 2014 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.97881 USF1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GSE40207_399_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nephritis CTD Gene-Disease Associations 1.0 1.1014 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null colonic adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.510992 Clara cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.5 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.845411 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34672 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3284 NCIH2172 CCLE Cell Line Gene CNV Profiles 1.0 1.72097 NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.58168 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.26631 cytoplasm GO Cellular Component Annotations 2015 1.0 null 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene HMDB Metabolites of Enzymes 1.0 null FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9245 Glutathione S-transferase, C-terminal InterPro Predicted Protein Domain Annotations 1.0 null planum polare, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29891 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3055 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7745 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.905577 Liver Cirrhosis, Experimental CTD Gene-Disease Associations 1.0 1.78968 COV504 DepMap CRISPR Gene Dependency 1.0 2.03434 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69I-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Glutathione DrugBank Drug Targets 1.0 null Kidney Failure, Chronic HuGE Navigator Gene-Phenotype Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6385-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.350743 A2BAR_Deficiency_GDS3662_520_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Atrophy CTD Gene-Disease Associations 1.0 1.16269 ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.48467 MECP2_KD_GDS4759_334_mouse_E16 primary cortical neuron cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.82549 Fetal Death CTD Gene-Disease Associations 1.0 1.45936 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1962 orbital frontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.954706 rectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.180535 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Papilloma CTD Gene-Disease Associations 1.0 1.3382 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29966 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07162 NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -2.19984 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20233 hsa-miR-4684-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Necrosis CTD Gene-Disease Associations 1.0 2.46027 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE150_OESOPHAGUS CCLE Cell Line Proteomics 1.0 2.56974 PPARG JASPAR Predicted Transcription Factor Targets 1.0 null amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.896463 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene HMDB Metabolites of Enzymes 1.0 null nucleotide GeneRIF Biological Term Annotations 1.0 null MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1545 (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene HMDB Metabolites of Enzymes 1.0 null CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rectal cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.50471 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.6094 foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.10887 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rectal cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.490229 NCIH23_LUNG CCLE Cell Line Proteomics 1.0 2.17683 BRL-3A cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.896 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0217 extracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.04087 PMC7730811-13148_2020_983_MOESM1_ESM.xlsx-Table_S3C_HNF4A_Target_Genes-Table_S3C_HNF4A_Target_Genes_Average_Colon_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null gallbladder HPA Tissue Protein Expression Profiles 1.0 1.0151 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.935264 Bromobenzene-2,3-oxide HMDB Metabolites of Enzymes 1.0 null A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13648 PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null COLO680N DepMap CRISPR Gene Dependency 1.0 3.46518 JOSD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17368 SCS214 DepMap CRISPR Gene Dependency 1.0 2.61747 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.958589 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0461 Hepatomegaly CTD Gene-Disease Associations 1.0 2.33527 k-562 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.55607 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1279 skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057182 RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TIA1_KO_GSE54418_263_mouse_spinal cord GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null USF1 ENCODE Transcription Factor Targets 1.0 null COLO684 DepMap CRISPR Gene Dependency 1.0 3.61604 SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6038 molecular layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06397 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.924815 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.941574 hippocampus (hippocampal formation)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.873365 NB7 DepMap CRISPR Gene Dependency 1.0 6.16039 ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5279 NCOA2_KO_GDS4785_172_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Learning Disorders CTD Gene-Disease Associations 1.0 1.65045 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Water HMDB Metabolites of Enzymes 1.0 null intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.364139 NCIH226 DepMap CRISPR Gene Dependency 1.0 5.95857 Internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 Drug metabolism - cytochrome P450 KEGG Pathways 2026 1.0 null (1S,2R)-Naphthalene 1,2-oxide HMDB Metabolites of Enzymes 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Glutathione MW Enzyme Metabolite Associations 1.0 null Stomach Neoplasms CTD Gene-Disease Associations 1.0 1.15156 lung TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054071 AKAP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3765 primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.79371 TDOTT DepMap CRISPR Gene Dependency 1.0 2.15826 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 NCIH28 DepMap CRISPR Gene Dependency 1.0 2.24416 Hypertrophy CTD Gene-Disease Associations 1.0 1.95721 H4-II-E-C3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.062 MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9002 Glutathione S-transferase, alpha class InterPro Predicted Protein Domain Annotations 1.0 null HCC4006 CCLE Cell Line Gene CNV Profiles -1.0 -1.82569 Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null 1-Nitronaphthalene-7,8-oxide HMDB Metabolites of Enzymes 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.52938 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.373 Nr5a2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.8663 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07162 supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33203 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.0948 NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3867 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22091 Glutathione S-transferase, C-terminal-like InterPro Predicted Protein Domain Annotations 1.0 null Scd1_DELETION_GDS4910_309_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Leukopenia CTD Gene-Disease Associations 1.0 1.27564 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12244 liver TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.697808 colorectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.235167 Hepatic Encephalopathy CTD Gene-Disease Associations 1.0 1.07022 EFM19_BREAST CCLE Cell Line Proteomics 1.0 2.82197 Renal Insufficiency CTD Gene-Disease Associations 1.0 1.34401 posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.876621 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0923 Heart Defects, Congenital CTD Gene-Disease Associations 1.0 1.1786 associations GeneRIF Biological Term Annotations 1.0 null PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1603 CAPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -1.63837 colonic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.458373 Gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.051 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7521 glutathione metabolism KEGG Pathways 1.0 null COR-L26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.972659 HCC70_BREAST CCLE Cell Line Proteomics 1.0 6.12337 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4395 Anemia, Hemolytic CTD Gene-Disease Associations 1.0 1.26978 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2406 Precancerous Conditions CTD Gene-Disease Associations 1.0 2.10841 Liver Diseases CTD Gene-Disease Associations 1.0 2.0725 Liver Cirrhosis CTD Gene-Disease Associations 1.0 1.34227 HCC366 CCLE Cell Line Gene CNV Profiles 1.0 2.78295 CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.37498 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895491 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.866148 OCIAML2 DepMap CRISPR Gene Dependency 1.0 2.23871 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.834875 Nuclear receptors meta pathway WikiPathways Pathways 2024 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Get-1_Deficiency_GDS2629_161_mouse_embryonic skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07162 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7316 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34364 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.834875 hsa-miR-1183 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 EGR1-23403033-LIVER-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null cytosol COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.24713 RFXAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47476 Lamina epithelialis mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.529 disease GWASdb SNP-Disease Associations 1.0 0.024486 NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5101 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09499 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53412 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.6231 PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.224 Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dyslipidemias CTD Gene-Disease Associations 1.0 1.05015 HOXA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5625 Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.751911 SKPNDW DepMap CRISPR Gene Dependency 1.0 2.07988 CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9402 bone marrow TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064089 CTCF ENCODE Transcription Factor Targets 1.0 null IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.96272 posterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08826 Micronuclei, Chromosome-Defective CTD Gene-Disease Associations 1.0 1.64955 glutathione metabolic process GO Biological Process Annotations 2015 1.0 null amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20236 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M5-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.841704 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975406 Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Reactome Pathways 2014 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SCA1_Knock-in_GDS3544_562_mouse_Cerebellum - 12 Weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null kidney cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064238 Lung squamous cell carcinoma_LUSC_TCGA-77-6845-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.102 Disease Reactome Pathways 2014 1.0 null urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.327896 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861415 catalytic activity GO Molecular Function Annotations 2015 1.0 null active GeneRIF Biological Term Annotations 1.0 null PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17067 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.954267 aging GAD High Level Gene-Disease Associations 1.0 0.293278 colorectal cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.4914 PANC0327 CCLE Cell Line Gene CNV Profiles 1.0 1.55247 hippocampus (hippocampal formation)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53618 ESX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64955 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051989 Feather vane TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.44 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0782 lateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01743 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8037 SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.865554 glutathione-mediated detoxification HumanCyc Pathways 1.0 null RAJI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.851162 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null PMC12276197-18_2025_5784_MOESM1_ESM.xlsx-Sup_Table_10-Supplementary_Table_10_ERK_targets_from_Unal_et_al_2017_mapped_to_human_orthologous_genes_from_KD_and_SC_hypernetworks_AR Rummagene Transcription Factor Associations 2026 1.0 null ZNF784 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.047 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.986185 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06872 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16015 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.52507 bone marrow cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077561 H3K27me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23113 Hepa-1c1c7 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.237 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13215 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041214 myeloid leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.113342 Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.853818 Glutathione conjugation Reactome Pathways 2024 1.0 null Inflammation CTD Gene-Disease Associations 1.0 2.29264 Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2758 Kidney Tubular Necrosis, Acute CTD Gene-Disease Associations 1.0 1.43564 HAE cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.12 Central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.595255 PPM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36129 Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27759 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3297 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GPRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47033 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059889 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41256 PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3148 Feather TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.104 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null Primary pulmonary hypoplasia_Lung Tissue_GSE1363 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.97932 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.06521 increased susceptibility to xenobiotic induced morbidity/mortality MGI Mouse Phenotype Associations 2023 1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.125 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96387 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.70273 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.3575 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.22274 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13648 Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.75894 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1922 S-(2,2-Dichloro-1-hydroxy)ethyl glutathione HMDB Metabolites of Enzymes 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07162 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76903 CORL105_LUNG CCLE Cell Line Proteomics 1.0 3.04137 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13648 P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null phenethyl isothiocyanate CTD Gene-Chemical Interactions 1.0 null membrane-bounded vesicle GO Cellular Component Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adrenal gland HPA Tissue Protein Expression Profiles 1.0 1.0151 Lymphoma_burkitts(Daudi) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.840736 gstt1 GeneRIF Biological Term Annotations 1.0 null lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15906 subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.985724 Heart Diseases CTD Gene-Disease Associations 1.0 1.56582 polymorphisms GeneRIF Biological Term Annotations 1.0 null Thioredoxin-like fold InterPro Predicted Protein Domain Annotations 1.0 null CD79B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90974 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.88412 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COLO668 CCLE Cell Line Gene CNV Profiles -1.0 -1.4952 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03324 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.958589 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.971376 cell part GO Cellular Component Annotations 2015 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cognition Disorders CTD Gene-Disease Associations 1.0 1.65621 Thrombocytopenia_Megakaryocyte_GSE2527 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.01608 intracellular part GO Cellular Component Annotations 2015 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease Models, Animal CTD Gene-Disease Associations 1.0 1.42696 Acute Kidney Injury CTD Gene-Disease Associations 1.0 1.7556 GATA6-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02036 SP in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15837 Dehydrodolichyl diphosphate synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.886 Phenobarbital CTD Gene-Chemical Interactions 1.0 null TFAP2C-20629094-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PADI4 ChEA Transcription Factor Targets 1.0 null VHL_Deficiency_GDS3769_513_mouse_Immortalized embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null DAOY_CENTRAL_NERVOUS_SYSTEM CCLE Cell Line Proteomics 1.0 3.8133 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8987 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11935 DBH_KO_GSE33906_53_mouse_heart (E10.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Ensemble_gene_ID_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null primary auditory cortex (core)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05187 Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0716 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.893656 gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 1.02871 Hematuria CTD Gene-Disease Associations 1.0 1.10459 H3K9me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.796 carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.439123 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14438 cellular nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null CUX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.899 EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0663 NCIH3122 DepMap CRISPR Gene Dependency 1.0 2.06186 HOXD11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3132 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08643 ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4198 NCIH510 CCLE Cell Line Gene CNV Profiles 1.0 2.0069 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene HMDB Metabolites of Enzymes 1.0 null PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.204 Adenoma CTD Gene-Disease Associations 1.0 1.80303 (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene HMDB Metabolites of Enzymes 1.0 null TGBC52TKB DepMap CRISPR Gene Dependency 1.0 2.52881 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5893-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LI7 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 CLPP_KO_GDS4791_376_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 ARH77 DepMap CRISPR Gene Dependency 1.0 2.48221 NB1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00569 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2735 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068467 Bromobenzene-3,4-oxide HMDB Metabolites of Enzymes 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.473869 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4767 cyclophosphamide_rattus norvegicus_gpl1355_gse48407 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 Prostate adenocarcinoma_PRAD_TCGA-EJ-5495-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Glutathione conjugation Reactome Pathways 2014 1.0 null 1,2-Dibromoethane HMDB Metabolites of Enzymes 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nasopharynx HPA Tissue Protein Expression Profiles 1.0 1.0151 Cystitis CTD Gene-Disease Associations 1.0 1.30056 Chromosome Aberrations CTD Gene-Disease Associations 1.0 1.46015 Brain Diseases CTD Gene-Disease Associations 1.0 1.65489 Electron transfer flavoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.793 WDR77 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8158 KDM5A ENCODE Transcription Factor Targets 1.0 null 22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null HNF4alpha_KO_GDS1916_168_mouse_Embryonic liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69014 ROCK_INHIBITION_GDS3944_464_mouse_Forebrain astrocytes - 24 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null obesity GWASdb SNP-Disease Associations 1.0 0.703511 KML1 DepMap CRISPR Gene Dependency 1.0 2.91696 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.159903 Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74676 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54892 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1021 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.41546 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.8615 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP2C ChEA Transcription Factor Targets 1.0 null Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 2.0154 membrane-bounded vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 gstm4 GeneRIF Biological Term Annotations 1.0 null 4-hydroxy-2-nonenal detoxification HumanCyc Pathways 1.0 null GSE239844_8_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25624 Infertility, Male CTD Gene-Disease Associations 1.0 1.11843 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25957 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7224 hematopoietic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071539 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene HMDB Metabolites of Enzymes 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.841993 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.70444 POR_KO_GDS1349_497_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.15 Prostate adenocarcinoma_PRAD_TCGA-HC-7747-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Fluid shear stress and atherosclerosis KEGG Pathways 2026 1.0 null Astrocyte projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.706 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00842 RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7344 Vitamin C levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 gsta5 GeneRIF Biological Term Annotations 1.0 null transferase activity GO Molecular Function Annotations 2015 1.0 null KYAE1 DepMap CRISPR Gene Dependency 1.0 6.26539 CGN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36184 Butylated Hydroxytoluene CTD Gene-Chemical Interactions 1.0 null HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9095 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6359 glutathione metabolic process GO Biological Process Annotations 2025 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15747 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.990802 JUN-21703547-K562-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null A-CA-04-2009(H1N1)_Day1_22532695_GSE36328 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.54086 nutrition disease GWASdb SNP-Disease Associations 1.0 0.37576 COLO741 CCLE Cell Line Gene CNV Profiles 1.0 1.34492 disulfiram_homo sapiens_gpl14550_gse42318 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE124177_1_v_0_gonadotropins_human RummaGEO Drug Perturbation Signatures -1.0 null PITX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6322 Phase II - Conjugation of compounds Reactome Pathways 2024 1.0 null disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.419517 Wt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 75.9501 colonic cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.458759 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene HMDB Metabolites of Enzymes 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12404 SARS-ddORF6_84Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.83403 Alzheimer Disease CTD Gene-Disease Associations 1.0 1.01474 PSN1 DepMap CRISPR Gene Dependency 1.0 2.0968 MAX_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Wing TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.032 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.51631 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A72E-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00674 icSARS CoV_36Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.57435 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3929 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2814 CCLE Cell Line Gene CNV Profiles -1.0 -1.44825 forelimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073337 UACC893 DepMap CRISPR Gene Dependency 1.0 5.62679 BARX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9606 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5418 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6968 Nerve Degeneration CTD Gene-Disease Associations 1.0 1.46621 Neural Tube Defects CTD Gene-Disease Associations 1.0 1.14989 Drug metabolism - other enzymes KEGG Pathways 2026 1.0 null pleural fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.360409 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06309 PL4 DepMap CRISPR Gene Dependency 1.0 4.81541 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.82525 GATA1 ENCODE Transcription Factor Targets 1.0 null CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08808 Lhx8 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8643 Fetal Growth Retardation CTD Gene-Disease Associations 1.0 1.58584 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.40978 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1406 Neurobehavioral Manifestations CTD Gene-Disease Associations 1.0 1.16766 E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.0033 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22596 SUDHL8 DepMap CRISPR Gene Dependency 1.0 3.35035 Melanoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.028546 GSE239844_7_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.96388 organelle LOCATE Predicted Protein Localization Annotations 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61539 glutathione transferase activity GO Molecular Function Annotations 2015 1.0 null NCI-H510A COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 Prostatic Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MZ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hepatobiliary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.843008 primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26021 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057976 SMARCA4 ChEA Transcription Factor Targets 1.0 null TMK1 DepMap CRISPR Gene Dependency 1.0 5.13292 Keap1-Nrf2(Mus musculus) WikiPathways Pathways 2014 1.0 null orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44219 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sulfate HMDB Metabolites of Enzymes 1.0 null amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.953404 kahweol CTD Gene-Chemical Interactions 1.0 null Aflatoxin B1exo-8,9-epoxide-GSH HMDB Metabolites of Enzymes 1.0 null DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9623 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.616 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39231 HCC364 CCLE Cell Line Gene CNV Profiles -1.0 -1.95278 SLC27A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86605 primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2135 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68317 SET2 DepMap CRISPR Gene Dependency 1.0 2.10219 Urinary Bladder Diseases CTD Gene-Disease Associations 1.0 1.20295 STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26266 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.885956 H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Carcinoma, Squamous Cell CTD Gene-Disease Associations 1.0 1.23868 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.36757 liver cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.375743 overnutrition GWASdb SNP-Disease Associations 1.0 0.443289 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12354 CDK2AP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83059 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7296 lateral parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990371 DMS-53 COSMIC Cell Line Gene Mutation Profiles 1.0 null Digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 Hydrogen Peroxide CTD Gene-Chemical Interactions 1.0 null 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene HMDB Metabolites of Enzymes 1.0 null Thyroid Diseases CTD Gene-Disease Associations 1.0 1.38527 HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -1.38822 JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1465 PMC11811213-42003_2025_7604_MOESM1_ESM.pdf-11-ZNF514_ZNF514 Rummagene Transcription Factor Associations 2026 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null intestinal cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.447576 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 2.50488 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4039 JHH2 DepMap CRISPR Gene Dependency 1.0 2.89326 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7644-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064629 gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22246 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052808 Poisoning CTD Gene-Disease Associations 1.0 1.41202 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05782 Neoplasm Metastasis CTD Gene-Disease Associations 1.0 1.14816 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null JUN-21703547-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Nde TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.931 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null erythroleukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.362646 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8307 DICER1_KO_GDS4504_586_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.733617 leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065009 Lymphopenia CTD Gene-Disease Associations 1.0 1.05936 t30-blood-rna_female_1w MoTrPAC Rat Endurance Exercise Training -1.0 -1.75634 EM2 CCLE Cell Line Gene CNV Profiles 1.0 1.6613 Adenocarcinoma CTD Gene-Disease Associations 1.0 1.40176 Nr1h2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.2958 20460173-ImmPortCD40LandAnti-IgMvsControl GeneSigDB Published Gene Signatures 1.0 null MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0671 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6568 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05678 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.842506 EVSAT DepMap CRISPR Gene Dependency 1.0 2.37545 suggestive GeneRIF Biological Term Annotations 1.0 null UIMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63409 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2034 SP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30188 catalytically GeneRIF Biological Term Annotations 1.0 null Breast Neoplasms CTD Gene-Disease Associations 1.0 1.88753 GATA1_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null muscle GTEx Tissue Gene Expression Profiles -1.0 -0.960637 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12354 Aflatoxin B1 CTD Gene-Chemical Interactions 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29966 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.218613 interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05043 COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26158 Cardiomegaly CTD Gene-Disease Associations 1.0 1.05237 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02132 Hypb_Deficiency_GDS3641_522_mouse_Yolk sac from E9 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.5026 myeloid leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.305001 PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.834875 ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8023 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.21365 ECGI10 CCLE Cell Line Gene CNV Profiles 1.0 1.54696 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.082 Cytosolic aryl hydrocarbon receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.505 Hydrochloric acid HMDB Metabolites of Enzymes 1.0 null limb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068931 Weight Loss CTD Gene-Disease Associations 1.0 1.78168 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76201 Cardiovascular Abnormalities CTD Gene-Disease Associations 1.0 1.14989 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6773 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 121.496 HEC59_ENDOMETRIUM CCLE Cell Line Proteomics 1.0 4.43908 caco-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.496483 Naphthalene epoxide HMDB Metabolites of Enzymes 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Submucosal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.529 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30603 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49851 SP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03879 Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SARS-CoV_36Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.989433 salivary gland GTEx Tissue Gene Expression Profiles 1.0 1.03714 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.301 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028568 Ethoxyquin CTD Gene-Chemical Interactions 1.0 null H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6502 Chemical carcinogenesis - DNA adducts KEGG Pathways 2026 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895491 THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 LS123 DepMap CRISPR Gene Dependency 1.0 3.31392 number GeneRIF Biological Term Annotations 1.0 null Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.135 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00569 observed GeneRIF Biological Term Annotations 1.0 null inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40613 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04937 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.8671 Cardiomyopathies CTD Gene-Disease Associations 1.0 1.38527 PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Gene_name_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null NCO2 DepMap CRISPR Gene Dependency 1.0 2.27969 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.239913 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.882061 NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04967 vesicle GO Cellular Component Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rectal cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.490229 FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3431 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21079 digestive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.65543 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1635 Adipose - Visceral (Omentum) GTEx Tissue Gene Expression Profiles 2023 1.0 2.29877 Exanthema CTD Gene-Disease Associations 1.0 1.21141 N-acetylsphingosine CTD Gene-Chemical Interactions 1.0 null HT1197 CCLE Cell Line Gene CNV Profiles -1.0 -1.53428 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0512 glutathione transferase activity GO Molecular Function Annotations 2023 1.0 null