association	dataset	threshold value	standardized value
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21273
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25444
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12887
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19505
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
4940_MED18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.671856
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0893
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POLR2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10639
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05806
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Transforming growth factor beta activated kinase 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21434
2893_TAFA2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504225
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10431
8661_TAF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.690345
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
PMC11185845-NIHMS1996282-supplement-Table_S1.xls-TableS1_txt-CB_TBL1XR1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4839
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8549
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7785_SEPTIN2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.605896
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.542073
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64189
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20154
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11354
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76085
2789_EXOSC2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.643786
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.905
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287971
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PTPN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37937
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
9687_UTP6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.595145
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30208
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186647,GSE217288_1_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC42SE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5663
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2607
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19344
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39702
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
SPDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55976
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTSV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08788
10478_ZNF585A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.846423
GSE120612_4_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3263
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.4941
4950_MED27_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.785387
GSE119978,GSE180930_2_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GAMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4614
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04936
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14899
3865_HNRNPF_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.522591
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00766
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34146
GSE131649_4_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59902
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11112608-BLOODA_ADV-2023-011512-mmc1.pdf-26-ZNF512B_ZNF512B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23167
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05916
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38584
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.759592
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
859_BMS1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.610122
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8088
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0438
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
Macroglobulinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140074_1_v_0_kif20a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34083
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33414
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08055
ENSG00000286190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61692
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08218
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12251
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
4116_INCENP_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.568244
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10133
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183335,GSE183351_3_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13077
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45926
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304609
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.65073
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64778
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_13_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.714
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.9172
NUP214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06051
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09694
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07362
MED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21627
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32115
2784_EXOC7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.58157
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.2806
BF-27-HP68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213677
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23313
NME6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42763
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46178
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.45
SLC35B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76169
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
2795_EXOSC8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.570711
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62997
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Blood 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-11.9095
10569_ZNF705B_ENST00000443676.1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.643956
5462_NAPA_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.885052
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Up_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7339546-12915_2020_793_MOESM2_ESM.xlsx-Table_S12-Table_S12_common_twin_genes_in_one_HMR_core_region_between_cattle_and_human_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29053
GSE119345_2_v_4_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.8389
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4731
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.566
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6657
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr11_76401668_G_T_b38	GTEx eQTL 2025	1.0	9.903
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2142
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
5964_LTO1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.572505
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.905
SPRYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40309
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43785
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07835
2473_EDARADD_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.550461
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237138
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12031
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44215
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0995
2140_DEDD2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.537801
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.8798
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06276
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91727
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12147031-NIHMS2026129-supplement-Supplemental_Material__Tables__Figures__and_original_Blots.pdf-18-HES6_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7413_RORA_ENST00000335670.6	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.503395
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAPK8IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51938
Mitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.544
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09382
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.198
LAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67009
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38163
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02747
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49868
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE156708_1_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369511
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29463
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Diffuse large B-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.054
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
2233_DIS3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.638955
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6422
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42252
GSE143692_0_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_0_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14969
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
LANCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44989
C8orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29346
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6866
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE200839,GSE233826_2_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.387074
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.679
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2434
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7255
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H4C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.57491
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.3654
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6143
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0768
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260678
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
2233_DIS3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.753524
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61898
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Chl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZFAND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68819
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57405
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02656
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09828
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3313
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7208
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.435
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246567_0_v_1_acat2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.976
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
6283_PHF19_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.663063
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48721
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_3_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
9684_UTP20_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.54294
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
105_ACTG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.928485
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
8662_TAF2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.677342
GSE231829_0_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37761
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15366
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40497
5726_NOB1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.573489
2988_FBL_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.648963
2790_EXOSC3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.641098
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03646
NPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15474
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15115
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84937
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06717
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
2458_EBP_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.529763
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6354
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195559_3_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	226.282
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
5900_NUP62_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.508503
8662_TAF2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.620459
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8652
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11151
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1616
608_ATF5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.573672
Chronic lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8113
MRPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01868
RPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36934
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.448
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6421
LIPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92739
GSE210101,GSE210114_11_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_14_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
C1QTNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17387
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01222
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65675
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.281
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TWIST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49976
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.718656
6576_POP5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.577877
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.6627
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50879
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.539
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75782
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
GSE159049_3_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20263
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7141_RBBP5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.641357
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16939
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07704
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44373
GSE102187_0_v_1_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28298
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334235
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.9765
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
2789_EXOSC2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.579949
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
10738_ZWINT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654479
ZNF449	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0864
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9687
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
8666_TAF5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.889073
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201902
2792_EXOSC5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.870483
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.4833
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12711
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CXCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43522
GSE197532,GSE197533_0_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12232
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.094
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.154
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PPP1R13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02989
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE189336_1_v_0_nitric oxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1051
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
2793_EXOSC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.837965
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.417
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
3986_HSPE1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.783768
KHNYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2357
RRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10773
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13991
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.773103
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19907
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE99687_3_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13325
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
PMC12147031-NIHMS2026129-supplement-Supplemental_Material__Tables__Figures__and_original_Blots.pdf-18-ENSG00000144485_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27474
WDR45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16129
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1552
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19452
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
4150_INTS5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.625404
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20801
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7203476-Table_3.XLSX-Sheet1-GV_MI_overlap_227_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16919
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84788
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.6139
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0404
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7473
GDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09682
2795_EXOSC8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.54672
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_6_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
301_ANAPC10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.600317
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.821
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69953
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211128_9_v_8_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75949
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99881
PMC12178829-mmc4.xlsx-Sheet_3-MEG3-KD_Down-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.037
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.9536
TPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13308
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17564
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41639
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8586
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0759
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66211
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.572
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
4651_LRP8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.697185
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4263
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.6932
GSE133087_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
6446_PLEKHJ1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.54845
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200805
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47593
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
LUBAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.995
GTEx Breast 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-3.2511
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0816
2793_EXOSC6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.590694
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05274
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2647
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29368
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39657
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.454
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30628
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27873
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TXNDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03207
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45406
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3967
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09249
CIAPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25698
8653_TAF12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.572464
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183335,GSE183351_3_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091