association dataset threshold value standardized value Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chromatin organization GO Biological Process Annotations 2015 1.0 null perilemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28793 mantle zone of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16632 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.66313 isthmic part of basolateral isthmic reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86488 Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17359 MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.56755 CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23281 intermediate part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25064 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.78522 KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78722 septopallidal core nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2094 rostral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57097 SNCA_KO_GDS4153_444_mouse_Cerebellum - 21 month GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleosome assembly GO Biological Process Annotations 2015 1.0 null BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.52855 medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.6267 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.17541 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.899269 r4 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05874 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.946684 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.94748 superficial stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02541 liminal part of alar isthmus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73445 T84 COSMIC Cell Line Gene Mutation Profiles 1.0 null mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.89822 HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.933576 NCI-H1568 COSMIC Cell Line Gene Mutation Profiles 1.0 null SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38065 substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87278 SAP30 ENCODE Transcription Factor Targets 1.0 null JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.95334 PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39434 RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4758-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Type 1 diabetes mellitus_T lymphocyte_GSE10586 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.34371 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.850376 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27042 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null r5 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04503 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39846 hsa-miR-224 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40334 CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00685 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.77298 cellular component assembly GO Biological Process Annotations 2015 1.0 null H3K9me3_U2OS_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.853599 sirolimus_mus musculus_gpl7202_gse27784 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MOLM13 Achilles Cell Line Gene Essentiality Profiles 1.0 1.31892 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12097 septostriatal part of the olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16415 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.99678 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30019 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20436 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828218 Prostate adenocarcinoma_PRAD_TCGA-VP-A879-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3202 NFYA JASPAR Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.857069 navicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07734 Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Parabrachial nucleus, lateral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.48636 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular component organization GO Biological Process Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00685 hsa-miR-4476 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 OCIAML5 Achilles Cell Line Gene Essentiality Profiles -1.0 -3.24852 hsa-miR-588 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 H3K9me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.95834 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basomedial amygdaloid nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13315 nicotine_myzus persicae_gpl9470_gse18658 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Medial septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1869 KNS62 CCLE Cell Line Gene Expression Profiles 1.0 1.54714 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85045 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.65481 external segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05172 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828218 Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41674 DND41 CCLE Cell Line Gene CNV Profiles 1.0 1.46155 pyramidal layer of taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55186 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14251 intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39434 uterine cervix TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null nucleosome organization GO Biological Process Annotations 2015 1.0 null KKU100 DepMap CRISPR Gene Dependency 1.0 3.76014 Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4701-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38874 SW620 CCLE Cell Line Gene Expression Profiles -1.0 -1.81535 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19087 isthmic basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12926 MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53131 KP363T DepMap CRISPR Gene Dependency 1.0 3.69478 ELF1 ChEA Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5786-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02137 mRNA_TCF7L2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.345805 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828218 r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07355 Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.865706 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78548 Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null layer 2 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13684 hsa-miR-2054 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 DMS53 CCLE Cell Line Gene Expression Profiles -1.0 -2.23999 BT474 CCLE Cell Line Gene CNV Profiles -1.0 -1.37182 intermediate stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37503 A172 CCLE Cell Line Gene CNV Profiles -1.0 -1.79682 NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.40695 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TYKNU CCLE Cell Line Gene Expression Profiles 1.0 1.39076 Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16897 MYC ENCODE Transcription Factor Targets 1.0 null mRNA_SUZ12_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null TYKNU DepMap CRISPR Gene Dependency 1.0 2.71824 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.900046 Parabrachial nucleus, lateral division, ventral lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45564 nucleus of Barrington Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18209 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null KALS1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.75975 outer CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30798 intermediate stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45925 NCIH1581 CCLE Cell Line Gene Expression Profiles -1.0 -3.99808 Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUDHL4 CCLE Cell Line Gene CNV Profiles 1.0 1.69204 A_CA_04_2009_4dayMOI-10^5_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.58256 COLO678 DepMap CRISPR Gene Dependency 1.0 2.70394 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948271 Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43592 CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.23627 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.6267 COV644 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.57936 Nucleus of the lateral olfactory tract, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00108 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.62972 hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.47289 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.849088 NCIH23 CCLE Cell Line Gene CNV Profiles 1.0 1.35729 Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2935 DepMap CRISPR Gene Dependency 1.0 2.36026 Nucleus of the trapezoid body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.6267 Lobule II Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38781 NCIH2030 CCLE Cell Line Gene CNV Profiles 1.0 1.76229 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null LN428 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.00256 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r4 part of lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00108 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.945943 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49335 Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null superficial stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80356 D341MED CCLE Cell Line Gene CNV Profiles 1.0 2.20946 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OTX2_KO_GSE27630_51_mouse_brain (fourth ventricular choroid plexus, E13) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 ventrolateral part of isA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73445 Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23551 outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12751 SKCO1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.06634 mantle zone of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00367 retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.910388 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41569 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55186 Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Basomedial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11802 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22999 NFYB ENCODE Transcription Factor Targets 1.0 null mRNA_MYC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null anterodorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.827165 r6 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23917 Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30664 Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2940-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.33069 HCC1359 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.56524 hsa-miR-1205 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 UO31 CCLE Cell Line Gene CNV Profiles 1.0 1.50293 dorsal peduncular cortex, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00655 Pancreatic adenocarcinoma_PAAD_TCGA-IB-8127-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.807436 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945681 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PECAPJ15 DepMap CRISPR Gene Dependency 1.0 7.29844 intermediate stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33836 medial parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.86228 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null dorsal terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3587 isthmic part of mesencephalic trigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.28028 Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.38934 NCIH889 CCLE Cell Line Gene CNV Profiles -1.0 -1.68746 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.33069 Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.94318 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 pontine hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13684 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null mRNA_ID1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null superficial stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18381 r6 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67676 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.899515 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67173 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.953602 substantia nigra, pars compacta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21354 nucleus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 MPP89 CCLE Cell Line Gene CNV Profiles -1.0 -1.54754 Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SOD2_KO_GDS1080_128_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null NCIH2291 CCLE Cell Line Gene Expression Profiles -1.0 -1.55919 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00983 anterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855469 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59101 HCC1599 CCLE Cell Line Gene CNV Profiles 1.0 2.075 heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09496 layer 5 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11754 lateral group of nuclei, right, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.884373 SW579 CCLE Cell Line Gene CNV Profiles 1.0 1.54895 Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKMM2 CCLE Cell Line Gene Expression Profiles 1.0 1.45178 RPE1SS48 DepMap CRISPR Gene Dependency 1.0 3.05393 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00983 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A3Y1-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.726392 H3K9me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03779 RARRES1_KD_GDS4818_314_human_SUM149 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21678 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2805 mRNA_SMAD7_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null substantia nigra, pars reticulata, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1937 liminal part of the r6 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85612 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null liver GTEx Tissue Gene Expression Profiles -1.0 -0.94101 ES-I3 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.02213 protein-dna complex subunit organization GO Biological Process Annotations 2015 1.0 null NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.53592 outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.968475 r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.06641 GATA2_01_61 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60438 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.830152 HH CCLE Cell Line Gene Expression Profiles 1.0 1.4978 HCC89 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09625 Temporal association areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01187 mRNA_SFPI1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null KU1919 CCLE Cell Line Gene Expression Profiles -1.0 -1.70116 NCIH1648 CCLE Cell Line Gene Expression Profiles -1.0 -1.55109 chromosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Retrosplenial area, lateral agranular part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44379 mRNA_GADD45A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14251 Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09272 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.827489 island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59869 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23921 HS737T CCLE Cell Line Gene Expression Profiles -1.0 -2.42504 hsa-miR-9 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15486 Parabrachial nucleus, medial division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54821 Otx2_KO_GDS4440_143_mouse_fourth ventricular choroid plexus tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13684 KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.931356 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-01A-21R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Histone core InterPro Predicted Protein Domain Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KC-A4BL-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.16682 TE15 Achilles Cell Line Gene Essentiality Profiles 1.0 1.11844 NCI-H727 COSMIC Cell Line Gene Mutation Profiles 1.0 null mRNA_ETV3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null A3KAW CCLE Cell Line Gene CNV Profiles -1.0 -1.44022 hsa-miR-193a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 r7 part of the basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57097 dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00317 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.911209 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GCIY CCLE Cell Line Gene Expression Profiles 1.0 1.49106 OELE Achilles Cell Line Gene Essentiality Profiles -1.0 -1.0858 PATU8988S CCLE Cell Line Gene Expression Profiles 1.0 1.65057 medial part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23917 Anterior olfactory nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02784 LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851839 Medial preoptic nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30537 Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HJ-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960627 non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SLR23 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.82733 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 nuclear part GO Cellular Component Annotations 2015 1.0 null SW48 DepMap CRISPR Gene Dependency 1.0 2.79508 SUDHL4 DepMap CRISPR Gene Dependency 1.0 2.62073 Medial amygdalar nucleus, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48415 globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10805 r5 part of the oral Sp5 subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18381 MDAMB453 Achilles Cell Line Gene Essentiality Profiles 1.0 2.73612 H1 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.65827 hsa-miR-510 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 NUDUL1 CCLE Cell Line Gene Expression Profiles 1.0 1.45101 HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.64692 periventricular stratum of the PBC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.09534 Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00685 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14248 H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06147 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30497 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38188 hsa-miR-3120-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 CTCF ENCODE Transcription Factor Targets 1.0 null SARS-CoV NSP16_Day4_None_GSE49263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.43851 brain GTEx Tissue Gene Expression Profiles 1.0 0.876457 binding GO Molecular Function Annotations 2015 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44348 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-5047 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 DAUDI COSMIC Cell Line Gene Mutation Profiles 1.0 null UterusCorpus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.830711 NCI-SNU-5 COSMIC Cell Line Gene CNV Profiles -1.0 -3.03592 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00983 LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44896 r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19389 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.868403 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.08214 Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21318 biological_process GO Biological Process Annotations 2015 1.0 null mantle zone of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25064 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15597 HCC-78 COSMIC Cell Line Gene CNV Profiles -1.0 -3.03592 hsa-miR-3147 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.847431 Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.04723 A704 COSMIC Cell Line Gene Mutation Profiles 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996498 HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70869 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13604 Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNUC1 DepMap CRISPR Gene Dependency 1.0 2.18128 MYBL2_01_148 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.77916 Retrosplenial area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32824 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828218 Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11152 HTK CCLE Cell Line Gene Expression Profiles -1.0 -1.62314 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 hsa-miR-3140-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 HS172T CCLE Cell Line Gene Expression Profiles -1.0 -1.6045 NCIH1648 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.900046 reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.47408 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Retrosplenial area, lateral agranular part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36381 cellular component organization or biogenesis GO Biological Process Annotations 2015 1.0 null NFYB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48415 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43573 r6 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37503 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45734 r5 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02541 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD1 JASPAR Predicted Transcription Factor Targets 1.0 null dna packaging complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.009118 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.84201 liver BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.917331 LUDLU1 CCLE Cell Line Gene Expression Profiles 1.0 1.51349 hsa-miR-4651 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 SNU449 CCLE Cell Line Gene CNV Profiles -1.0 -1.77101 HT115 CCLE Cell Line Gene CNV Profiles 1.0 1.42686 hsa-miR-545 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Taenia tecta, dorsal part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28024 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.901163 MYC_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DBTRG05MG DepMap CRISPR Gene Dependency 1.0 4.12634 reticular formation of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68486 globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29073 Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01535 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18882 SUM1315MO2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.879943 mantle zone of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25064 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6034 ovary GTEx Tissue Gene Expression Profiles 1.0 1.14534 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A705-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_NR0B1_19530134 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NB10 DepMap CRISPR Gene Dependency 1.0 11.0815 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13172 Retrosplenial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34 MDAMB361 CCLE Cell Line Gene CNV Profiles -1.0 -1.64036 inner CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835219 EB1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.92033 V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16057 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.54696 ventral part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26343 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91499 Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2047 NCIH146 CCLE Cell Line Gene CNV Profiles 1.0 1.53241 BXPC3 CCLE Cell Line Gene CNV Profiles 1.0 2.02396 hsa-miR-4681 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.827489 III Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.86947 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-619 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08608 Brain Lower Grade Glioma_LGG_TCGA-DU-6394-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21083 Retrosplenial area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84719 CHP212 CCLE Cell Line Gene CNV Profiles 1.0 1.93509 hsa-miR-4646-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.769182 NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28257 H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.15076 r8 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41409 NCIH596 CCLE Cell Line Gene Expression Profiles -1.0 -2.41197 uterus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50222 MAX ENCODE Transcription Factor Targets 1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.47026 superficial stratum of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07808 Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20417 protein heterodimerization activity GO Molecular Function Annotations 2015 1.0 null HS839T CCLE Cell Line Gene Expression Profiles -1.0 -2.64713 CAL62 CCLE Cell Line Gene CNV Profiles 1.0 1.84465 Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH7 CCLE Cell Line Gene Expression Profiles 1.0 2.22358 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.21615 MKN45 CCLE Cell Line Gene CNV Profiles -1.0 -1.37725 cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00983 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.98338 cingulate cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16681 protein complex assembly GO Biological Process Annotations 2015 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null KE39 CCLE Cell Line Gene Expression Profiles 1.0 1.42489 fallopian tube GTEx Tissue Gene Expression Profiles 1.0 1.07419 NCIH2122 Achilles Cell Line Gene Essentiality Profiles 1.0 1.50719 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKMEL24 CCLE Cell Line Gene CNV Profiles 1.0 1.59691 Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.873947 MCIXC DepMap CRISPR Gene Dependency 1.0 5.06527 BXPC3 DepMap CRISPR Gene Dependency 1.0 3.93097 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1-20517297-JURKAT-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1299 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 intermediate stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25188 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12743 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of spinal trigeminal nucleus, pars oralis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04503 Spinal nucleus of the trigeminal, oral part, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33836 KNS62 CCLE Cell Line Gene CNV Profiles 1.0 1.72486 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.996248 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53976 SUDHL8 CCLE Cell Line Gene Expression Profiles 1.0 1.86036 Retrosplenial area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24767 AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.62358 C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00095 Lung squamous cell carcinoma_LUSC_TCGA-22-5492-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chromosomal part GO Cellular Component Annotations 2015 1.0 null inner CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.893621 Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRF JASPAR Predicted Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2429 DepMap CRISPR Gene Dependency 1.0 2.3116 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890781 hsa-miR-296-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22914 Lung adenocarcinoma_LUAD_TCGA-55-8087-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 4 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85123 lateral septal nucleus, intermedio-dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04361 Parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01489 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30413 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08748 DNA binding GO Molecular Function Annotations 2023 1.0 null protein dimerization activity GO Molecular Function Annotations 2015 1.0 null upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.63412 hsa-miR-3156-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 superficial stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16439 molecular_function GO Molecular Function Annotations 2015 1.0 null C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22632 SK-MES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4ZB-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KM12 CCLE Cell Line Gene CNV Profiles 1.0 1.61496 MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.4561 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26892 Brain Lower Grade Glioma_LGG_TCGA-P5-A77X-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Parabrachial nucleus, medial division, medial medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60357 r6 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39434 SF172 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.42409 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1056 nucleus of the central acoustic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67676 hsa-miR-3689d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 PATU8902 DepMap CRISPR Gene Dependency 1.0 3.35556 H3K9me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Basomedial amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23997 SNU5 CCLE Cell Line Gene CNV Profiles -1.0 -2.3514 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JE-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XJ-A83F-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2909 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996498 Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globus pallidus, external segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09454 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73482 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25086 r6 part of ventral gigangocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05874 internal female genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null dna bending complex GO Cellular Component Annotations 2015 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null isthmic liminal part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59522 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42553 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.26811 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RN-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OC314 DepMap CRISPR Gene Dependency 1.0 3.40513 Superior olivary complex, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43592 intracellular organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBFbeta_Deficiency_GDS3577_557_mouse_Regulatory T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Superior olivary complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91499 hsa-miR-608 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.91447 cervical carcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null lateral superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.6267 VCAP CCLE Cell Line Gene CNV Profiles -1.0 -2.09287 intermediate stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0063 SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91592 globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15922 rhombomere 6 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6034 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16511 hsa-miR-4750 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3467 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.44124 Midbrain trigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94823 Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07905 hsa-miR-194 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-362-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 isthmic liminal reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04216 C10 DepMap CRISPR Gene Dependency 1.0 2.26846 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.38849 hsa-miR-874 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Basolateral amygdalar nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44871 IGR1 CCLE Cell Line Gene CNV Profiles -1.0 -1.60807 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IE-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57336 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05478 VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35127 NCIH1395 CCLE Cell Line Gene Expression Profiles 1.0 3.26069 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.66476 L-428 COSMIC Cell Line Gene Mutation Profiles 1.0 null laterodorsal tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30158 isthmus proper Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82677 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.46769 Periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41197 RERFLCSQ1 CCLE Cell Line Gene CNV Profiles -1.0 -1.5564 Lung squamous cell carcinoma_LUSC_TCGA-77-7465-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06655 PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.49193 mRNA_NR2F2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41409 outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14383 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08027 cellular_component GO Cellular Component Annotations 2015 1.0 null VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.872885 Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01287 superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.06641 D502MG DepMap CRISPR Gene Dependency 1.0 4.38061 MGMT Pathway Commons Protein-Protein Interactions 1.0 null Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.841106 intermediate part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75884 dorsal periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57097 dentate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.977661 TC71 CCLE Cell Line Gene CNV Profiles 1.0 1.38353 KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21923 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13972 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH647 CCLE Cell Line Gene CNV Profiles -1.0 -1.8646 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09496 SNUC2A Achilles Cell Line Gene Essentiality Profiles 1.0 1.938 SNU-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.933576 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997276 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86346 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06272 Prostate adenocarcinoma_PRAD_TCGA-EJ-A6RA-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17384 zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922843 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.73044 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19309 hsa-miR-1301 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 superficial stratum of CCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16632 organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 r4 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53976 mRNA_EP400_22196727 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.47529 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17945 SNU5 CCLE Cell Line Gene Expression Profiles -1.0 -1.7583 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21735 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.876449 superficial stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04503 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.19685 Prelimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03773 Magnocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.06641 hsa-miR-642a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 JHUEM7 CCLE Cell Line Gene CNV Profiles -1.0 -1.70701 Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2805-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null globus pallidus, internal segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08842 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.963218 cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 periventricular stratum of r1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12314 spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18888 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02542 I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.948606 JJN3 CCLE Cell Line Gene Expression Profiles 1.0 2.48897 Fog2_KO_GDS3659_152_mouse_adult heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null septohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54384 HCC3153 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.299 mantle zone of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04503 nucleic acid binding GO Molecular Function Annotations 2015 1.0 null HS944T Achilles Cell Line Gene Essentiality Profiles -1.0 -1.0933 CAKI1 CCLE Cell Line Gene Expression Profiles 1.0 1.47205 hsa-miR-539 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 chromosomal part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW1573 CCLE Cell Line Gene CNV Profiles -1.0 -2.00402 SNU1079 DepMap CRISPR Gene Dependency 1.0 2.91469 macromolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27067 intermediate stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14611 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00685 Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT20 CCLE Cell Line Gene CNV Profiles -1.0 -1.34633 membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 ROS50 DepMap CRISPR Gene Dependency 1.0 3.25512 NCIH841 CCLE Cell Line Gene CNV Profiles 1.0 2.3786 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.905882 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_MYOD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.865239 pretectal nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.859356 medial part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04503 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30664 KARPAS299 CCLE Cell Line Gene Expression Profiles -1.0 -1.64046 RT11284 DepMap CRISPR Gene Dependency 1.0 5.20395 Sarcoma_SARC_TCGA-KF-A41W-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHU029 DepMap CRISPR Gene Dependency 1.0 5.53979 Nucleus of the optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40217 reticular formation of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06973 estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null dna binding GO Molecular Function Annotations 2015 1.0 null WM1799 CCLE Cell Line Gene Expression Profiles -1.0 -1.71064 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41409 Retrosplenial area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57598 TE9 Achilles Cell Line Gene Essentiality Profiles 1.0 1.46954 hsa-miR-3686 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 EW-24 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-3915 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46B-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11427 hsa-miR-3663-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 hsa-miR-329 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 chromatin COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -2.0876 mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11914 SNU1 CCLE Cell Line Gene Expression Profiles 1.0 1.74924 superficial stratum of r5BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.16682 KE97 CCLE Cell Line Gene Expression Profiles 1.0 1.93192 Leukemia, Acute Megakaryocytic_Megakaryocyte_GSE2433 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.49481 1321N1 CCLE Cell Line Gene CNV Profiles -1.0 -1.47278 HLF Achilles Cell Line Gene Essentiality Profiles -1.0 -1.6403 DOT1L_DELETION_GDS4295_427_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 5 days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67305 KRAP_Deficiency_GDS3528_564_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-3153 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78548 Facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85612 Major island of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09282 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.52483 rhombomere 7 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09558 accumbens nucleus, shell domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06511 SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.893955 Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BHY COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral part of the isB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23527 intracellular part GO Cellular Component Annotations 2015 1.0 null Anterior cingulate area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02058 RI1 CCLE Cell Line Gene CNV Profiles -1.0 -1.92896 KYSE-70 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lobule II, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27296 medial part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21644 Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HHUA DepMap CRISPR Gene Dependency 1.0 2.87092 nucleosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05153 muscle GTEx Tissue Gene Expression Profiles -1.0 -2.01659 MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.963154 NCIH1838 CCLE Cell Line Gene CNV Profiles -1.0 -1.328 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-UT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4437 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07355 hsa-miR-4793-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.93302 organelle part GO Cellular Component Annotations 2015 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null protein complex GO Cellular Component Annotations 2015 1.0 null SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.61983 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HT-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-875-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 TrigeminalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.975152 EGI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null LS513 Achilles Cell Line Gene Essentiality Profiles 1.0 1.12722 IM9 DepMap CRISPR Gene Dependency 1.0 4.02666 hsa-miR-4761-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 HCC2218 Achilles Cell Line Gene Essentiality Profiles 1.0 1.30407 HS821T CCLE Cell Line Gene Expression Profiles -1.0 -1.70756 dorsolateral (non-cerebellar) part of isA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00435 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEPG2 CCLE Cell Line Gene Expression Profiles -1.0 -1.78171 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 MDAMB361 CCLE Cell Line Gene Expression Profiles -1.0 -1.68307 Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.865685 JHOS-4 COSMIC Cell Line Gene CNV Profiles -1.0 -3.03592 KASUMI2 CCLE Cell Line Gene Expression Profiles 1.0 1.50125 Infralimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01575 Orbital area, medial part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02541 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07171 r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11914 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Brain Lower Grade Glioma_LGG_TCGA-QH-A65Z-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEC2 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.87267 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01734 rhombomere 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37503 nucleus sagulum, deep part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25142 PMC5436210__F3 PFOCR Pathway Figure Associations 2023 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G361 CCLE Cell Line Gene CNV Profiles 1.0 1.44347 Pontine central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00823 NCIH716 CCLE Cell Line Gene Expression Profiles 1.0 2.1066 locus coeruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43125 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null rhombomere 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53976 hsa-miR-4704-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null nuclear nucleosome GO Cellular Component Annotations 2015 1.0 null Lobule II, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45155 intermediate part of StrSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04337 NMC-G1 COSMIC Cell Line Gene CNV Profiles 1.0 2.14588 hsa-miR-4733-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 pontomedullary hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6034 intermediate stratum of SePal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10776 COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872971 mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null layer 3 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32494 Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRL_Deficiency_GDS1693_236_mouse_Photoreceptors cells of retinas at P2 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Childhood Acute Lymphoblastic Leukemia DisGeNET Gene-Disease Associations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4599-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUPT1 CCLE Cell Line Gene Expression Profiles 1.0 1.67305 SKBR3 CCLE Cell Line Gene CNV Profiles -1.0 -1.48756 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null soft tissue HPA Tissue Protein Expression Profiles -1.0 -0.891519 protein-dna complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 LOU-NH91 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01724 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.04593 D341Med DepMap CRISPR Gene Dependency 1.0 3.60491 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.869952 H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26343 ES-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43706 ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21644 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.74916 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.931356 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKNAS CCLE Cell Line Gene CNV Profiles 1.0 1.4256 parabrachial complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16531 septopallidal shell area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06902 hsa-miR-668 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 periventricular stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40782 BDCA4+_DentriticCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.52918 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27528 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCP1 CCLE Cell Line Gene Expression Profiles 1.0 1.38752 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.922886 dorsal part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0032 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.993977 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.6267 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70587 Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A673 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.11595 NO36 DepMap CRISPR Gene Dependency 1.0 2.81956 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.34994 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.868231 SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.853312 CHLA06ATRT DepMap CRISPR Gene Dependency 1.0 2.61305 OCUM1 DepMap CRISPR Gene Dependency 1.0 2.01016 layer 2 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10999 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48151 nucleus coeruleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04048 cell part LOCATE Predicted Protein Localization Annotations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lateral septal nucleus, rostral (rostroventral) part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00296 MFE280 CCLE Cell Line Gene CNV Profiles 1.0 1.32957 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macromolecular complex GO Cellular Component Annotations 2015 1.0 null Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07193 Locus ceruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34823 THP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.87443 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30561 intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K9me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.735652 Parabrachial nucleus, lateral division, central lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.1997 HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.904459 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.11412 Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61479 r5 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25064 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.31006 intermediate stratum of isBL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86514 SUDHL10 CCLE Cell Line Gene Expression Profiles 1.0 2.07698 JHOS4 CCLE Cell Line Gene CNV Profiles -1.0 -1.42524 mantle zone of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22725 horizontal nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27686 HCC202 DepMap CRISPR Gene Dependency 1.0 2.04648 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.7132 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828218 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null SW872 COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70869 CNR_KO_GDS2820_636_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-3128 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.86566 intermediate stratum of the PBC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.86228 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.987173 mantle zone of the PBC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16531 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MU-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AU565 CCLE Cell Line Gene CNV Profiles -1.0 -1.40476 BFTC-909 COSMIC Cell Line Gene Mutation Profiles 1.0 null OVK-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pons, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3232 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.931156 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cellular macromolecular complex assembly GO Biological Process Annotations 2015 1.0 null lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.952146 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parabrachial part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.09534 Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32199 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral wings of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07364 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spinal nucleus of the trigeminal, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33836 macromolecular complex subunit organization GO Biological Process Annotations 2015 1.0 null SREBF1 JASPAR Predicted Transcription Factor Targets 1.0 null OTX2_KO_GDS4440_424_mouse_brain (fourth ventricular choroid plexus) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5361-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45925 Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.975744 Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53763 22RV1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.00178 facial motor nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54242 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05688 Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JIMT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null CDK8_knockdown_147_GSE32108 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.72941 SW780 CCLE Cell Line Gene Expression Profiles -1.0 -1.94769 r6 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23917 LN319 Achilles Cell Line Gene Essentiality Profiles 1.0 1.74126 Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-6178-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.37697 layer 1 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17359 Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macromolecular complex assembly GO Biological Process Annotations 2015 1.0 null ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.89663 SJRH30 COSMIC Cell Line Gene CNV Profiles -1.0 -3.03592 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.31484 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of isBL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70974 Bed nucleus of the accessory olfactory tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53976 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7176 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r8 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32199 hsa-miR-576-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LB1047RCC DepMap CRISPR Gene Dependency 1.0 2.38906 S117 CCLE Cell Line Gene Expression Profiles -1.0 -2.31297 hsa-miR-330-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.70188 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-593 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.098 18614019-TableS4d GeneSigDB Published Gene Signatures 1.0 null KYO1 DepMap CRISPR Gene Dependency 1.0 2.4081 dna bending complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.010431 KARPAS422 DepMap CRISPR Gene Dependency 1.0 2.82653 intermediate stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06462 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09496 SW 780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.864115 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.827489 HS675T CCLE Cell Line Gene CNV Profiles 1.0 1.84676 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null VIIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.830084 Retrosplenial area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59341 HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.69084 UMUC11 DepMap CRISPR Gene Dependency 1.0 10.0578 dna packaging complex GO Cellular Component Annotations 2015 1.0 null INA6 DepMap CRISPR Gene Dependency 1.0 3.21745 protein-dna complex GO Cellular Component Annotations 2015 1.0 null Gigantocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04503 Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09936 outer CP in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14629 Nucleus of the lateral olfactory tract, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06603 mantle zone of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0381 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6228-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Histone H2B InterPro Predicted Protein Domain Annotations 1.0 null SJRH30 CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 RH30 CCLE Cell Line Gene CNV Profiles -1.0 -2.20312 cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 KYSE-450 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01933 COLO680N CCLE Cell Line Gene CNV Profiles 1.0 2.55556 Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8012-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.958958 NCIH841 DepMap CRISPR Gene Dependency 1.0 5.55857 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.912507 CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.47446 nuclear chromosome part GO Cellular Component Annotations 2015 1.0 null intracellular organelle part GO Cellular Component Annotations 2015 1.0 null superficial stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08321 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2716-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-326 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Parabrachial nucleus, lateral division, dorsal lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98795 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16511 PTEN_01_302 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.64631 lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.919657 superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6034 SQ1 CCLE Cell Line Gene Expression Profiles 1.0 2.51458 icSARA deltaORF6_36Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.40829 neuropeptide-S nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46046 Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.03945 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12867 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35835 superficial stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05201 adrenal gland GTEx Tissue Gene Expression Profiles -1.0 -0.932174 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12666 Medial preoptic nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05725 mantle zone of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85612 protein-dna complex assembly GO Biological Process Annotations 2015 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.04985 superficial stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00108 NCIH1563 CCLE Cell Line Gene Expression Profiles 1.0 1.61009 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21443 breast HPA Tissue Protein Expression Profiles -1.0 -1.38279 protein complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.001526 protein complex subunit organization GO Biological Process Annotations 2015 1.0 null Parabrachial nucleus, lateral division, superior lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.03217 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19236 nucleosome GO Cellular Component Annotations 2015 1.0 null layer 5 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20916 HS839T CCLE Cell Line Gene CNV Profiles 1.0 1.40026 Retrosplenial area, ventral part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45905 intermediate stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53976 Medial amygdalar nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57097 r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13684 PLCPRF5 CCLE Cell Line Gene Expression Profiles 1.0 1.67738 Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-504 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Entorhinal area, medial part, dorsal zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13684 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.976364 Brain Lower Grade Glioma_LGG_TCGA-R8-A6MO-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05154 Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM4C_natural variation_GSE41040_590_human_fibroblasts fron neonatal foreskin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NFIC JASPAR Predicted Transcription Factor Targets 1.0 null NCI-H841 COSMIC Cell Line Gene CNV Profiles 1.0 2.14588 WM1799 DepMap CRISPR Gene Dependency 1.0 3.7409 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874443 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54141 Retrosplenial area, lateral agranular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28816 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.0348 rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.344535 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.02508 nucleoplasm GO Cellular Component Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4725-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD4 ChEA Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VK-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19618 KMS12BM Achilles Cell Line Gene Essentiality Profiles 1.0 1.00363 isthmic part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.46738 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.828218 SK-MEL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.53787 IGROV1 CCLE Cell Line Gene Expression Profiles -1.0 -1.71173 DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.02058 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21644 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30484 mantle zone of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82677 E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal peduncular area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11633 Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.827489 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cortical amygdalar area, posterior part, medial zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03148 H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NZOV9 DepMap CRISPR Gene Dependency 1.0 2.5623 shell of SCH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39434 E2F6 ENCODE Transcription Factor Targets 1.0 null MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16592 SARM_KO_GDS4842_412_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28554 Histone-fold InterPro Predicted Protein Domain Annotations 1.0 null G-401 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.33069