association	dataset	threshold value	standardized value
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3458
Facioscapulohumeral muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.191
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.813
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8182
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.82126
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.4483
Facioscapulohumeral muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.056
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
FACT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
Anus benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Systemic lupus erythematosus	KEGG Pathways 2026	1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	99.4
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.814
U7 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
HIR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.484
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.92945
Retinal telangiectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
Adult astrocytic tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Alpha thalassemia-X-linked intellectual disability syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4055
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6692
496100373_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.55695
Adductor magnus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9604
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.795
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
h4ii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
h4s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.04688
Clear cell chondrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6318
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0513
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5834
Transcriptional misregulation in cancer	KEGG Pathways 2026	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8066
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8893
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.203
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.059
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.598
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.924
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5131
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90463
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8385
Neutrophil extracellular trap formation	KEGG Pathways 2026	1.0	null
Cell surface furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
Shigellosis	KEGG Pathways 2026	1.0	null
Histone mutated tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
CENP-A containing chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44159
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
nucleus	GO Cellular Component Annotations 2025	1.0	null
CENP-A containing nucleosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.591
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.203
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1921
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.7486
Alpha thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1667
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.3416
INO80-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.981
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
Alcoholism	KEGG Pathways 2026	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7803
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7104
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.323
Bolting stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
Diffuse midline glioma, H3 K27M-mutant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.83
MutSalpha complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.792
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.61905
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
b18	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1962
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.48183
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0203
mv.1.lu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.521
Chondroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.088
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2785
PMC5446900-NIHMS72240-supplement-Table_S1.xlsx-Table_S1-Table_S1_Genes_differentially_expressed_in_human_primary_myoblasts_upon_ectopic_expression_of_DUX4_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
chromosome, centromeric core domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100588_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.89633
Chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.438
Floating-Harbor syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.29201
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4945
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8201
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3856
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0145
MTERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07512
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2756
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.6184
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.794
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7278
Heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.726
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8429
CENP-A recruiting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1588
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.24885
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1893
Facioscapulohumeral muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.315
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.79021
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2087
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.016
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5439
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.3666
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.963
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7444
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.12837
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
Musculoskeletal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1483
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1669
Lsm1-7-Pat1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.018
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7632
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1304
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.198
PMC5735185-41467_2017_1200_MOESM4_ESM.xlsx-Table_S1-Choi_et_al_2016_DUX4_up-regulated_targets_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Methylosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7044
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9375
TOM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
Vastus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
Methyl accepting chemotaxis protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
senescence-associated heterochromatin focus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.819
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.712
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.997
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2648
Coats disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.87
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7807
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9327
Connective tissue benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3
Pericentric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.467
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0943
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.96817
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0961
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8325
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7605
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8749
MBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0733
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4249
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.05099
alpha-thalassemia myelodysplasia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
Somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.686
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.5863
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
Swr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.184
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
Germinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
Chondroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.813