association dataset threshold value standardized value DENND11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91305 CAVIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15127 PSMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77805 CASKIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.69487 NF1 copy number variation syndrome WikiPathways Pathways 2024 1.0 null PIH1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81814 DEPDC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56813 Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.013 PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_EC_CSc_vs_NB_CSc_MSC Rummagene Transcription Factor Associations 2026 1.0 null PMC11519470-41467_2024_53624_MOESM1_ESM.pdf-52-TWIST1_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null HMMR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26678 Histone modifications WikiPathways Pathways 2024 1.0 null ESRRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38277 SLAIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58844 ZNF597 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00691 496100555_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07639 BHLHE23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45412 ARL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05259 NPFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91819 UGP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12118 ZNF844 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56213 ZNF665 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58943 EMC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.6493 AP2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82695 ZSCAN20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65085 RFX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29898 Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.026 Lymphatic system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF Rummagene Transcription Factor Associations 2026 1.0 null UBN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66564 SLC5A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68375 RIPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.07254 TMEM126A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.829 WNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53765 ECE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62606 ATF6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.16438 PDS5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20947 TMEM150A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40961 PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null RNASE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95184 IDH3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69418 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.468 MRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1509 AGO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.046 ANXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66846 PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null PMC12480273-12672_2025_3611_MOESM1_ESM.xlsx-csgene-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GATA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08335 B3GALNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68735 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.037 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.331 Extraocular retinoblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 RSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90887 PHGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1751 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 P3H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45626 HUS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29483 496100359_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.0747 PTPRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8012 PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B Rummagene Transcription Factor Associations 2026 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.695 PIP4P2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44643 SP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07507 PMC7773550-mmc4.xlsx-A-Table_S3_A_Differently_expressed_genes_FC_1_5_p-value_0_05_in_response_to_HyIL6_MSC_or_HyIL6_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null SMARCAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66854 C11orf96 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22447 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.664 RRAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40371 LYRM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92673 SIKE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67664 JUN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43524 ZDHHC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46948 HBEGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55319 ETV3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61466 BRI3BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59069 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.098 TBC1D24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55832 EIF3I CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28445 ZNF257 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97295 Respiratory system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 NUTM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9786 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.252 Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 MTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81502 Mood disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.037 PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB Rummagene Transcription Factor Associations 2026 1.0 null UGGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99951 PMC3371315-NIHMS350140-supplement-8.xls-MCF7-T47D-SK-453_Down_MCF7-T47D-Supplementary_Table_1_ER-positive_FOXA1_signature_Genes_decreased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null HSPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48875 LAMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59931 KCNJ11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24272 LAMB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33906 Schizophreniform disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 MFNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64608 CIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38088 TLCD3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13804 Male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.13 PRDM16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18467 PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null PMC7488531-13287_2020_1914_MOESM10_ESM.xlsx-HNF4A_regulated_DEGs_750-Unnamed_1_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null CAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12856 KDM4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37368 SP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63992 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 ASB16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58364 ZCRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03706 SAR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38779 Whole Blood GTEx Tissue Gene Expression Profiles 2023 1.0 1.82506 GJA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01297 PRMT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05195 ACAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36519 DUT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52515 Developmental disorder of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.817 REXO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63354 ZNF684 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20179 NFU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46451 C8G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28151 Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.133 RSBN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47025 NIBAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03398 DDX52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26195 LAMA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25895 Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.259 SSR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39625 RPS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59842 CCDC9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95649 Brain - Nucleus accumbens (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.11683 PAPOLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07098 RAB32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53096 FOXR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34254 UBQLN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56257 Brain - Hippocampus GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.11683 ZNF32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6786 UCHL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55465 CLCN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20837 SENP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76378 IRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41346 CTH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15237 ZFAND2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.36448 SCAMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27164 ZNF705A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56583 ZNF229 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4337 PDCD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90972 TMEM243 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69898 NAGPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1724 FBXL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16689 ZNHIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50359 BRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22195 BSPRY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82643 DNTTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06552 PRODH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3307 RUSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80749 USP42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27752 PARP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61415 HSP90AB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52766 EPS15L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85218 PRRT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10822 MMADHC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86918 TOR1AIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93333 WDR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22377 Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.329 PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1 Rummagene Transcription Factor Associations 2026 1.0 null PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null FEZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73834 TBX21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55736 Heart - Atrial Appendage GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.749092 ZNF596 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.36412 CHPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64957 DCAF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47879 MYF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01681 SOX14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99352 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.111 TM6SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22415 TRAF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84295 DMAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15273 Nucleotide excision repair in xeroderma pigmentosum WikiPathways Pathways 2024 1.0 null RARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0512 TCEA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26997 Prostate disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.915 PRKAR2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.71269 SETD1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10483 PTPRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54573 PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1 Rummagene Transcription Factor Associations 2026 1.0 null PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR Rummagene Transcription Factor Associations 2026 1.0 null G0S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30907 496100463_FWM_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07614 CHST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46199 ZBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94666 ZNF518A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.01442 ELMOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56207 SUOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51534 ARHGAP35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17222 Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.163 MXD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40061 FMO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.86776 C1orf50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07171 UQCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49338 PMC3912072-pone.0087850.s004.docx-0-List_of_promoters_positive_for_HA-E2F1_1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null Sebaceous gland disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.621 NR3C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94227 FOXP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69504 ODC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34512 KAT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1603 CLUH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37045 XYLT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18985 ZFP36L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.28271 NR2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6048 ROR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59397 POU3F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45436 LPCAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07668 PMC8758144-elife-74272-supp3.xlsx-AP1_REP1-GeneName_JUN Rummagene Transcription Factor Associations 2026 1.0 null Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.366 MAST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.174 DRGX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48634 STX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44238 FAM200B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85509 Major depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.037 OPTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47038 Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.13 CHFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35015 TPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62728 OAZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98409 Cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.037 FASTKD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60978 TMEM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66486 PMC4387713-supp_gad.255984.114_Table_S3.xlsx-S3A-Down_Dpy30_KD-Unnamed_1_AR Rummagene Transcription Factor Associations 2026 1.0 null ASPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51691 HOXC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1613 ACTN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97253 NFXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30766 NAA20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35186 GBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92675 PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR Rummagene Transcription Factor Associations 2026 1.0 null VAV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45258 NEUROG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18125 HRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14516 MRPL44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40045 IFFO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6538 Prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.136 ZSCAN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60759 CYB5R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39232 Lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null CNEP1R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6736 ACBD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24513 Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173 TSPAN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02196 TMEM69 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57438 SLC29A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40207 HIP1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80264 DACT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15857 STRIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60049 RAB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21832 ZGRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73527 PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null 496100548_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07625 SCYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03484 ERGIC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62216 ZNHIT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76061 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.699 SPATS2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.29273 Male reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.915 PIGU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47659 Systemic lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.307 MYEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94728 BIRC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80653 FBLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62591 BCKDK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13869 ZNF638 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55007 PRRG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73578 PSMB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07909 C5orf34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39426 WDR5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63597 MRPL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5755 NKX3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58826 NR2E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13236 Carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null PPP2R5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08814 SIK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58812 ACHE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54882 ATXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30338 H2AC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18213 YLPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75253 PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_name_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null YIPF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44068 DHX33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4612 RECQL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64004 WARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7417 MOCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71546 WBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17642 HTR1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1147 MATN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07547 PDZD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8817 TMEM229A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36415 GFI1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04343 WDR53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56138 Juvenile pilocytic astrocytoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.245 PI4KA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26115 MDH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24321 ZNF568 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60321 NEUROD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4669 SPRYD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45485 Adrenal Gland GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.11683 RAPGEFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52986 NUFIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35494 PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null NELFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18391 ZDHHC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75209 SIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40425 THTPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6788 BGN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82234 RPS6KA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02518 RBIS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58344 IFNLR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36299 NSUN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60662 RPIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93882 POLR2K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96443 UBXN2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03898 STRN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48631 FOXL2NB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52779 ANKRD34B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32262 SNTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99942 TSC22D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62066 BCKDHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41875 ACKR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74812 ATXN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82167 WDR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12395 MRFAP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.13698 MUS81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.12809 MRPL32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37707 SWAP70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35813 SLC25A37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69879 MKNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0734 TSPAN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35152 NKX1-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18661 GLI4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62711 C14orf132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73511 CSPG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83569 Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.261 H4C14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28202 RNPEPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.587 PRMT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04765 NECTIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15783 ARHGEF39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68761 SPIN2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65284 SLC2A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8857 HILPDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39002 PRR14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67217 TTLL12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71007 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.422 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.165 ZBTB43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74757 TMEM245 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97223 H2AC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8066 PNN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61289 Skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.621 TTYH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31623 Acne DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.621 CRTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62024 SAP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02174 MICU2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45084 ZUP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56553 WIPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54211 LYSMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50086 MRPL45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95001 NMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54015 LAPTM4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40728 MTARC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76442 MESP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01087 ZFP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14807 PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Hepatobiliary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 PMC10200789-41392_2023_1466_MOESM5_ESM.xlsx-TFs_target_genes-Top_100_targetGene_BACH2_BACH2 Rummagene Transcription Factor Associations 2026 1.0 null TEX264 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13775 Adipose - Subcutaneous GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.11683 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.814 UBR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31476 ZNF878 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11207 CREBRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96022 HSF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25904 496100365_HIP_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07428 SARAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76449 PAPSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29065 PGK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77099 DNMT3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04158 ZNF611 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27981 NPEPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50886 DMAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0347 TP53INP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50587 EDARADD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95107 PTDSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85252 PMM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80291 CALM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15505 Senescence associated secretory phenotype SASP WikiPathways Pathways 2024 1.0 null ZNF680 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46246 TAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22409 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.239 PCDHB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23506 EVX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16297 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 SEC16A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97598 GRK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17753 CCDC92B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50248 ADGRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71826 Lung squamous cell carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.574 GNL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51225 CPNE9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60217 Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.246 ZNF761 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22225 CIAO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60054 ZFP92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3114 CHST6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56766 FOXB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30152 ZFTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.67593 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.757 PDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4981 Fanconi renotubular syndrome 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.885 ZBTB42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23663 TSR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8845 PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.033 Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 EIF2AK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07272 BICRAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27205 ANKRD13D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33042 496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07607 E2F8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97546 ARHGEF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19592 NFKBIE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50366 EPB41L4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97741 DRAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67438 Brain - Cerebellar Hemisphere GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.11683 GNG12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.54183 ZNF600 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48285 ZNF585A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58656 Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null NLRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97114 PMC8160578-JCB_202009147_TableS4.xlsx-MYBL2_targets-Genes_n_532_MYBL2 Rummagene Transcription Factor Associations 2026 1.0 null 496100371_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07412 NPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30704 post-traumatic stress disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.635 PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null ZBTB41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15703 PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null ABL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20406 CASTOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.812 SRY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31332 ZNF263 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6273 HSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86488 CNOT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82637 Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.278 496100444_HIP_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.0766 BACH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79532 Cells - Cultured fibroblasts GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.11683 PMC7863452-12920_2021_883_MOESM2_ESM.xls-SRG_23_HCC_vs_17_NT-GENENAME_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null LRP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.90208 CCDC107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.11529 KXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23197 496100504_TCx_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07596 TBC1D10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66846 PRKCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73376 HACD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.56466 GOLT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6662 RUFY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23508 GRHPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36312 RNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68672 Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 RRP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58443 ERMAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06739 BCAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26033 Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066 MBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.37547 CCNG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0647 Prostate disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.134 COQ9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43007 HELLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6043 LEMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5146 Chronic obstructive pulmonary disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.245 MED26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.589 AQP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07147 COX7A2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90685 BLOC1S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3038 CHAF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03086 PPFIA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42905 TOP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22237 STK11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71442 PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2 Rummagene Transcription Factor Associations 2026 1.0 null XPO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07526 CSTF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07222 KLRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04204 MAD2L1BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41738 ERVV-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59751 GNA12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70579 MTHFD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24669 PMC12824906-mmc5.xlsx-Sheet1-Table_S4_Target_genes_of_FOXM1_and_their_expression_across_the_subtype_of_breast_tumors_FOXM1 Rummagene Transcription Factor Associations 2026 1.0 null GLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92988 STK10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67991 KIF18B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11651 ACSM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5794 Female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.112 PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3 Rummagene Transcription Factor Associations 2026 1.0 null ST14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59268 GDAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38578 Anxiety disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.635 ARL6IP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37262 SLC36A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52012 COPS7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28895 SOX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33137 Substance dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 DHRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45432 ECHDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28919 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.346 SMYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.34159 CLNS1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08206 CDKN2AIPNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45969 LRRC75B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46845 PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null RAD51C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.295 Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_18_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null PMC7863452-12920_2021_883_MOESM5_ESM.xls-SRG_13_GE2-HCC_vs_17NT-GENENAME_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null ACVR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26718 GPR137 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33797 DSEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63828 Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.037 PBXIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.02043 MON1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24841 Delusional disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.104 FAM104B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89983 PMC10203545-Table_4.xlsx-LM7_underrepresented-DMRTA1_DMRTA1 Rummagene Transcription Factor Associations 2026 1.0 null PLEKHG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87973 FGFR1OP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84381 TNNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13726 OLIG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38672 MFSD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90144 DUSP16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44206 E2F4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11386 ZMPSTE24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0245 ARG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7088 PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC Rummagene Transcription Factor Associations 2026 1.0 null PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_27_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null ACTG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18333 GGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4336 TFIP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97489 USP17L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78783 ULBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64885 Alpha thalassemia-X-linked intellectual disability syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 Intraocular retinoblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 PMPCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50217 SF3B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38846 AIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97073 PMC12224833-12967_2025_6787_MOESM3_ESM.xlsx-DEGs_PDX1-GeneSymbol_PDX1 Rummagene Transcription Factor Associations 2026 1.0 null CTTNBP2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0264 RTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61607 Depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.065 VTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57363 PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR Rummagene Transcription Factor Associations 2026 1.0 null POU6F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18139 CDK17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.825 OTX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12773 YJEFN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36034 ALG10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82563 TADA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69897 TBL1XR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46647 PMC7927818-AAC.01755-20-s0002.xlsx-Supplemental_Table_1-Supplemental_Table_1_List_of_significantly_altered_genes_in_MDMs_differentiated_in_the_presence_of_PrEP_FTC_v_No_Drug_TDF_v_No_Drug_FTC_v_TDF_SRY Rummagene Transcription Factor Associations 2026 1.0 null RAD9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27453 TBCCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72068 496100520_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07591 FAM91A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63405 CPEB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82885 Melancholic depression DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.037 Prostatic hypertrophy DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.915 WASF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39964 CBS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45109 ZNF221 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38987 PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null SLC25A45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92729 Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.206 PJA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30598 ARID1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72453 PIWIL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84481 RNASEH2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37473 FOXD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0189 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.163 SSBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99245 KLHL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87587 MSH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20958 METTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70034 Lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.307 RGS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.68763 PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null CUX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13647 PDXP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2125 PEX13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12123 KDM5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88617 KAT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2518 ACTN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90997 BARD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72461 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_47_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null NANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0558 CCDC74A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56478 C9orf78 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0238 TPGS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.62852 TXNDC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01372 TOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56106 HSPA12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69252 SLC1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55642 PDHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50695 CDC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.66043 FOXP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.26343 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.06998 MFSD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93614 FAM53B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98029 KLK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85734 POU3F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50465 TMSB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.94139 PPP2R5E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06543 496100330_PCx_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07467 CHGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1894 RYBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83938 Reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.915 FOXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1166 EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 PRICKLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62038 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.281 PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null NKAPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36803 Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.036 HOXD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05563 IREB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10373 RPL18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55627 CXCR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.53792 PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16 Rummagene Transcription Factor Associations 2026 1.0 null Nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.354 UBTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48919 TUBA1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96659 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.34 RASGRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91374 ATP5MC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73026 DNASE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35531 CLN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61648 Autism spectrum disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.817 GDPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.71466 TRIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14173 PDZD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76407 NIPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30443 PMC8296523-13287_2021_2498_MOESM1_ESM.docx-0-sc-RNAseq_EGR1_cell_trajectory_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null CLC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17059 TYMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68373 Hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 MAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62474 PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_up_VENN-697_elements_included_exclusively_in_HIF1_genes_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null ALDH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85758 CLDN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50966 Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.263 RPS26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72374 HOXD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39323 TAF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13876 LHX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03187 CCDC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51726 SIRT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1998 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.258 PABPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91396 Lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 KCNK15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00196 ZNF792 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57105 SPI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12206 Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 ATF7IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81306 Central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.095 MOV10L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36432 PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53 Rummagene Transcription Factor Associations 2026 1.0 null MSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40378 PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR Rummagene Transcription Factor Associations 2026 1.0 null VPS13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43354 NCKIPSD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64626 ELP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96832 SLC38A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24686 YWHAG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66729 MAP1S CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64147 TCL1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26253 H4C13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79487 ZNF865 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99835 CSGALNACT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25121 Respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 HNRNPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07198 SLC9A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94512 Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.111 CLDND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.56056 Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 GJA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32838 Lymphatic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.041 496100381_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07509 MTFMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06997 ZNF112 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74484 ACTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96903 ZNF462 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65597 DDX19B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27055 C4orf46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6521 CETN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00945 PTTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47744 DLGAP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18473 ATAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38839 UNKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35913 ZNF333 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19761 TDRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86232 ANKMY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75607 PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_id_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null MTMR11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37345 MTMR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45865 ZNF99 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70835 FUT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66544 PMC11639743-mmc2.xlsx-LIN28B-gene_name_LIN28B Rummagene Transcription Factor Associations 2026 1.0 null NTMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97162 SCN4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21655 DHPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57021 MUC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33433 PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_CUTOFF_2_5_TOTAL-HAND1_HAND1 Rummagene Transcription Factor Associations 2026 1.0 null PDLIM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11498 NDC80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18948 PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2 Rummagene Transcription Factor Associations 2026 1.0 null HSPA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71296 PMC3470785-NIHMS377161-supplement-14.pdf-109-PDX1_PDX1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF433 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44264 KLF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41124 CNOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06211 CDK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07411 NANOS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61707 KIF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09943 SLC12A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6073 PFKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13366 RFK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92001 IFT20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53266 GAL3ST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.75578 PMC11625982-AJH-100-10-s001.pdf-71-ZNF709_ZNF709 Rummagene Transcription Factor Associations 2026 1.0 null SPATA20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96548 EXOSC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25352 PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null MAPKAPK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81041 PCBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00989 Lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 VPS37C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42515 CHMP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55008 PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null PROCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16111 MTERF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22479 PMC9805873-Supp_Data.xlsx-dCas9-SALL1-SDS3_SEL1L_indiv-id_SALL1 Rummagene Transcription Factor Associations 2026 1.0 null NEU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84964 LHX9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04555 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.223 PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null TBC1D22B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87979 PI4K2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78769 CRKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.8785 PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_1_AR Rummagene Transcription Factor Associations 2026 1.0 null PIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75997 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 LRRC45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64237 PLCB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.64214 TMEM256 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62057 PREPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44561 RPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23107 WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 SEL1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29064 CYP2S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15219 Squamous cell carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.574 PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null ACAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06862 H4C11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85171 LIN7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22085 ASB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43285 Depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.037 SRI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41522 PBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32791 ADAM33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80357 CNST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98051 TLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33306 EMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12962 TAX1BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90643 HOXB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4231 Female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.029 TSPYL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57952 GNE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.67782 RHBDF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58372 TBC1D20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04308 COX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85333 ZNF425 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99428 LANCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17634 Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.021 HOXA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.886 EPHA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.97756 C3orf52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66221 FKBP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75636 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null TRMT44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72621 PMC11459127-pnas.2406837121.sd04.xlsx-Sheet1-AR_AR Rummagene Transcription Factor Associations 2026 1.0 null ADGRG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79734 Lung carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 Unilateral retinoblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 ATP8B3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32327 496100559_FWM_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07637 C3orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79613 EPN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81689 CINP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22656 CELF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85325 PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18 Rummagene Transcription Factor Associations 2026 1.0 null ATP6V0E2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10357 Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.073 HOXC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81565 PMC8758144-elife-74272-supp3.xlsx-AP2_REP1-GeneName_GTF3A Rummagene Transcription Factor Associations 2026 1.0 null KIRREL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98426 TRO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4896 EDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39992 APBB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98765 IGF2BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66289 H1-8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71125 PMC8758144-elife-74272-supp3.xlsx-AP1_REP2-GeneName_JUN Rummagene Transcription Factor Associations 2026 1.0 null H2AC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14528 SLC66A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33752 CTSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03232 QRICH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27235 Immune system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 RPS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40092 F12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67726 ELOA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61931 PARD6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02729 UNC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39924 TNS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64029 MRGPRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44295 NID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2043 NEMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98339 PMC11568168-41598_2024_79607_MOESM3_ESM.xls-11-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null ALPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75942 VAMP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54571 ZNF41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99376 COA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34234 TADA2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40553 BAZ1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57779 PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null DICER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14569 PEDS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65268 CLCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72177 Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 FBXL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93405 496100338_HIP_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.0754 PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG Rummagene Transcription Factor Associations 2026 1.0 null MRPL21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.09951 Pervasive developmental disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.817 SMYD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32446 GATD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62177 HEATR5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01131 TRAF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19229 TCFL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68842 PUM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73456 Adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.083 FLNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40881 SELENOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72902 HNRNPUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00588 USP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58431 TATDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.065 ZDHHC20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94004 USP16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21003 RHOXF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31705 ZDHHC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96565 DOLK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31791 VDR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73972 UBE2H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58068 NOMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41362 HSPA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57546 PGBD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36879 ZC3HAV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98708 PMC8758144-elife-74272-supp3.xlsx-AP2_REP2-GeneName_GTF3A Rummagene Transcription Factor Associations 2026 1.0 null Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.249 FGFRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46058 PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521 Rummagene Transcription Factor Associations 2026 1.0 null MEGF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71248 HEY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26964 ROMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06257 UCHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5147 USP47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96072 FARSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37292 Lung cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066 PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1 Rummagene Transcription Factor Associations 2026 1.0 null Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.26 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.196 Lung non-small cell carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.574 PSORS1C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94019 SHOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01083 RNF112 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23301 ISLR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78275 ZSCAN25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20279 ZBTB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.02947 POLR2J2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14048 IER2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35403 AEBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5729 SNRNP70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41306 PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null SAP30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87156 PNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.28566 E2F6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32315 ELP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58008 NPIPA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75638 496100476_TCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07653 CTDNEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78223 FUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71531 Integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.621 CHCHD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.69447 LACTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99515 TMEM104 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94861 PALS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39154 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 ITPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33788 PLS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76835 PHF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.65157 GSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02416 MED6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42717 IRF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40249 Obstructive lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.245 ING4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66328 SLC16A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.31552 PMC7863452-12920_2021_883_MOESM6_ESM.xls-SRG_13_GE2-HCC_vs_10_GE1-HCC-GENENAME_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF160 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13897 496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07383 CERCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31329 FOSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4719 SOCS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00165 DPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09144 PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null MLYCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70589 ZFTRAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96174 FAM118A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11852 POLR2H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37493 Cell type cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 CFAP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3485 HIVEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93835 MTPAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71141 ATXN7L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91451 RRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10328 H3C8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43294 KLHDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32458 TBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94722 SMOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61324 ERBIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62391 TRPM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62733 GMCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18852 MEOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80627 MEAK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48085 NYAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.54851 PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR Rummagene Transcription Factor Associations 2026 1.0 null INO80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02775 Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.38 ASB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5895 AGPAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43746 ARF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72964 DHRS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30399 EBF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53906 THYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87374 NEK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43562 ZFP57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90916 DDR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.97657 PF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86345 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.0747 MYBPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83288 CCDC113 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50246 DTYMK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83299 EZR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76977