association dataset threshold value standardized value SLC6A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62969 TADA2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68617 MAEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87154 ZNF492 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43989 NPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31157 496100346_FWM_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.48288 ZNF212 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75776 PMC9691391-7945884.f3.pdf-0-ENSG00000008196_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null TGIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28901 HNRNPCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63707 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.13719 PTPN18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29775 DIP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19186 IFI16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87871 TM9SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34906 ELMOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47673 ENTREP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44102 496100321_HIP_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.20491 FAM3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59431 CAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12856 OLFML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27159 ZDHHC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98873 PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD Rummagene Transcription Factor Associations 2026 1.0 null MLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41677 GTF3C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99215 SHOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01083 Bone disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 RASL11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86942 RPS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59842 HK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81977 RAD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6474 PMC8758144-elife-74272-supp3.xlsx-AP1_REP1-GeneName_JUN Rummagene Transcription Factor Associations 2026 1.0 null PRRT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46675 PIGP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36757 ZNF606 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19304 RNF216 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78593 HABP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44053 ZNF559 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51874 TMEM168 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.966 DENND5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.92168 UCMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89114 SLC2A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95496 MOCS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30584 MYO5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86524 PLEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29124 HRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93944 EVX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16297 PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC Rummagene Transcription Factor Associations 2026 1.0 null ZNF766 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43293 DLGAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43227 C6orf226 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27733 JAG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46492 PLD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16858 496100598_PCx_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.10796 OSBPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68622 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.135 496100390_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01191 REPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65866 ALX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97056 SLC39A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40268 PHYKPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79277 BARX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10814 C2CD4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32719 DNAJC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20519 CCDC25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74537 HUS1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90663 Female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 Unilateral retinoblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 RB1CC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86846 TAPBPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50104 IP6K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61641 HPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13422 TCEANC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4585 PNKD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53877 DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 PMC12824906-mmc5.xlsx-Sheet1-Table_S4_Target_genes_of_FOXM1_and_their_expression_across_the_subtype_of_breast_tumors_FOXM1 Rummagene Transcription Factor Associations 2026 1.0 null CER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04528 ZNF107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27108 Lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.218 PRKRIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9559 USP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94783 NPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65517 POM121 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20954 MFSD14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16798 ZNF791 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77529 Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.293 THUMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46398 KLHL12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86324 496100324_FWM_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.57135 CNDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02148 YEATS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36007 KIAA0232 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90482 NDUFAB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27963 Senescence associated secretory phenotype SASP WikiPathways Pathways 2024 1.0 null ZNF222 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28156 COMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06122 PRDM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49608 PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-y_TFEB_KO_LLOMe_VS_WTLLOMe_UP_TFEB Rummagene Transcription Factor Associations 2026 1.0 null PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC Rummagene Transcription Factor Associations 2026 1.0 null NDUFA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03598 PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null SLC16A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31552 TRMT9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78002 TIGD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14338 SPIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71769 MAP3K4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49255 LLGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41889 POLR2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45794 ZNF843 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1833 PMC11568168-41598_2024_79607_MOESM3_ESM.xls-11-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null IGF1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53277 GBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53496 FUT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05464 KLHL15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22185 ARL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33912 GGCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84393 496100438_PCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.32316 Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.19 UBE2K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62004 BOLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19253 Lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 SLC25A19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27732 UBA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73404 FBXO17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28256 MYOCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3963 ZNF750 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91298 SULT2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87832 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.708 Nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.354 Fanconi renotubular syndrome 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.884 BRSK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35871 MPRIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38063 BCLAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40241 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.44139 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.412 CXCL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68224 SYPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70853 STK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42899 APAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57162 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.301 ZKSCAN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55312 Nucleotide excision repair in xeroderma pigmentosum WikiPathways Pathways 2024 1.0 null CXCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52706 PANK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36006 Potocki-Shaffer syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.026 CFP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69619 PCGF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87188 NLRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13659 GYG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83873 RDH14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32214 PSMA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73528 UBE2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3684 HOXC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43858 PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR Rummagene Transcription Factor Associations 2026 1.0 null C9orf72 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85933 VANGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48183 NCBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08643 PHIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27313 ACBD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73878 FLOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37031 PMC7069022-Table_1.xlsx-MYCN_Cor_Microarray_Analysis-GENE_MYCN Rummagene Transcription Factor Associations 2026 1.0 null RND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02787 TMED10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77397 UVSSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36155 Skin - Sun Exposed (Lower leg) GTEx Tissue Gene Expression Profiles 2023 1.0 2.2759 PPP1CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97212 UNCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03863 SIRT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30091 PBDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7422 ZNF648 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90654 BTN2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56037 MRPS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4796 PRKAG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18095 FAM98A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18569 MIX23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66186 RHNO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33069 Systemic lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.203 PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_1_AR Rummagene Transcription Factor Associations 2026 1.0 null KAT14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82403 EDEM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36973 High grade glioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.006 HCN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63789 STAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54043 PPFIA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77391 ZNF564 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84123 ZNF792 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67895 GLRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24258 SMARCAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66854 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.299 CNOT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4742 PMC12480273-12672_2025_3611_MOESM1_ESM.xlsx-csgene-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF Rummagene Transcription Factor Associations 2026 1.0 null Idiopathic scoliosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 FBXO27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90672 OGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35072 SDCBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11762 ERI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15483 SERPINE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56715 PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_DN_AA_DN-AA_DN_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null ARHGAP45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27902 CFAP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3485 ZNF540 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12236 CELSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62219 TLX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4253 LBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36953 AKT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73399 POGLUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80027 MFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99606 ARHGEF40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86122 GABRB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.52313 CLIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96647 NKIRAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84298 RIDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5089 ACSS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2007 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.119 Juvenile pilocytic astrocytoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.245 ZNF280D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13373 DRD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72037 NF1 copy number variation syndrome WikiPathways Pathways 2024 1.0 null TLCD3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18018 ACTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88016 PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null SNX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11132 LRRC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.67598 TIPARP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45461 TYMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68373 ZNF423 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83862 CLK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98641 DHCR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31981 Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.033 APEX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46298 RAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 Type II interferon signaling WikiPathways Pathways 2024 1.0 null DCUN1D4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71794 SOX15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46864 ZSCAN18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1641 PIANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17717 SKOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93502 CNBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10236 ZFP30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12362 GNAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21415 TRIM24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7488 NEURL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86636 PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_2_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null B3GNT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56531 IQGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88009 HSPA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27762 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.762 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.298 ZNF263 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6273 AK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20108 ZNF721 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89135 COMMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05983 ZNF333 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19761 ALPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75942 ZNF74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31935 PRAME CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09836 PEMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72622 TMEM88B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75684 ZNF727 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06846 SPRTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15808 PGAM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91853 NELFCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36282 TMEM106B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7075 CEP55 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7244 MAP4K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0307 RLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74771 PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null ASMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44095 MPST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16066 BBLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85485 PRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45699 B3GAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16782 SNX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34185 MCUR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75065 NR1I3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75007 USP33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97911 PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_14_PDX1 Rummagene Transcription Factor Associations 2026 1.0 null RIOK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78931 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 COX7A2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90685 SGSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88706 TRAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49006 UBE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39395 496100651_FWM_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.09145 FICD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52566 GFUS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30239 ADPRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68432 PHKG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4401 MOCS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37151 F12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67726 KDM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10054 ITPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22684 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.678 IRF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1051 CCDC71 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76428 WBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47311 TMEM86A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31676 Artery - Tibial GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.778137 PPP5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29339 CNOT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43729 FBLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5269 CERS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2097 PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4 Rummagene Transcription Factor Associations 2026 1.0 null MTAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37415 NPTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43121 PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null FSTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77051 BATF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94435 CTDSPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11292 KDELR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53265 JUNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29946 Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.188 ATG16L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66705 CPEB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32933 MYLIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78238 TMBIM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19775 DNER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91358 ISOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62987 BTN2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36976 L3MBTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78113 ZSWIM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60299 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.2557 ABCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.95509 XRCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12926 ZNF98 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76782 ME2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84383 DUT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52515 TMEM120B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15158 496100320_PCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.44994 IRF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11256 TOMM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46643 LEO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43212 PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null ZFP41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7474 EBLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43944 TXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75591 PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null TOR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97292 PPP1R11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64414 FEM1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21318 GJA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01297 UBXN2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03898 SPRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90691 Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.196 Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.35 MAML1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19806 496100366_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.09039 PMC12021929-Table1.docx-0-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null METRNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01755 PMC6802116-41467_2019_12517_MOESM5_ESM.xlsx-Sheet1-D9_8_GNF2-SERPINB5_CENPX Rummagene Transcription Factor Associations 2026 1.0 null PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53 Rummagene Transcription Factor Associations 2026 1.0 null SLCO4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9602 ARID5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50364 PLBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27447 Chronic obstructive pulmonary disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.225 SOX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92922 MKRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15339 OLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41588 PDXK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36826 C1QBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92318 PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_CUTOFF_2_5_TOTAL-HAND1_HAND1 Rummagene Transcription Factor Associations 2026 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 USP20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89891 FTCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71641 SEMA4F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88463 GTF3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90221 DNAJB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16232 NAP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25334 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.375 BCL9L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66214 HLX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98542 HOXA10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70854 PDK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36015 PGGHG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36625 SLC27A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8402 PDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4981 DSG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91122 PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null TEK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12688 SSBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88456 ACSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47254 PITX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81416 BAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27732 PLEKHF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87806 PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null SUMO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89857 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066 PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_DN_NR2F1_ind_DN-NR2F1_Ind_DN_NR2F1 Rummagene Transcription Factor Associations 2026 1.0 null MECP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.602 NEUROD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4669 ELK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42702 RASSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48746 TAF6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.286 CSNK2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12549 ZXDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3455 PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6B-Table_S6B_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_Type_II_LGG_CIC_Del_CIC Rummagene Transcription Factor Associations 2026 1.0 null FLI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54916 DDRGK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21838 CPNE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.786 ELL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74334 C8orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77473 TCF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42684 TMEM101 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34565 496100445_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.01287 Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null IZUMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07647 SPRY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92966 PACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46663 TRAF3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79478 PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB Rummagene Transcription Factor Associations 2026 1.0 null PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3 Rummagene Transcription Factor Associations 2026 1.0 null TUB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55272 BRD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92459 Esophagus - Muscularis GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.778137 FASLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10088 RNASE6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24409 EBNA1BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64546 IMPDH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45435 SEMG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05634 ANXA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05329 SPAG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46281 UNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75456 PMC12784616-12711_2025_1028_MOESM2_ESM.xlsx-TableS5-Table_S5_Summary_of_significant_MR_associations_in_blood_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.16 PHLPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1641 ZNF225 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39023 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.25 PMC11756367-peerj-13-18820-s001.xls-SP1-Target_SP1 Rummagene Transcription Factor Associations 2026 1.0 null ZFP69 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.89684 FOXN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88783 SBDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86424 ZDHHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5661 PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3 Rummagene Transcription Factor Associations 2026 1.0 null DPM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86726 Obstructive lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.225 PMC7553775-elife-61287-supp1.xlsx-Muller_2014_DREAM_bound_genes-Genes_KCNIP3 Rummagene Transcription Factor Associations 2026 1.0 null REEP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39916 MPZL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33663 ZEB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4742 ERBB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5018 496100336_TCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.45941 CACNA2D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36247 RHOU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91677 TEAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17686 SF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7969 DTWD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72602 TDRD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9205 MTMR9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29463 PRDM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51693 AAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26333 TIE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.26126 TNFRSF12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19199 HCN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12832 ECH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24605 COMMD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4543 MRPS18B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28162 LMO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7774 GCLC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54541 Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 TRIM36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74561 ZBTB41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15703 H2BC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38932 PMC4677459-NIHMS65392-supplement-Dataset3.xlsx-HIF1A-Unnamed_2_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null SLC16A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.04865 SLC2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2517 STAT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22646 BSX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40982 PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_7_CEBPB Rummagene Transcription Factor Associations 2026 1.0 null REXO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02424 PTTG1IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.952 TSPAN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00599 ICE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48102 NCOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3798 TBPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94226 DPP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69331 MAGED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51735 TRIM41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89181 DVL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52389 SLFN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22435 ITGB1BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99918 AGER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2585 SCMH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01781 COG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01352 C2orf49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87266 MFAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30664 USP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64226 496100347_PCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.38689 NELFE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72539 WHRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99069 PMC6772115-JCB-120-18332-s003.xlsx-MYC-Dataset_Gene_ID_MYC Rummagene Transcription Factor Associations 2026 1.0 null RASGEF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98537 SLC39A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07305 TEX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40798 Lysinuric protein intolerance DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.121 VAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7818 ANKRD50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83032 CENPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1632 CEP57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12064 SEC24A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87207 RFX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02115 CDC42SE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61871 AEBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82601 ANO8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7162 SMARCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29241 PIK3C2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1175 PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null CAPRIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06757 NPEPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50886 PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG Rummagene Transcription Factor Associations 2026 1.0 null KRTCAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36368 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.312 TSPAN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06693 ZMIZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86025 AGAP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57787 PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-DANG_BOUND_BY_MYC_MYC Rummagene Transcription Factor Associations 2026 1.0 null RNF125 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14727 Bone structure disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 PMC9490101-mmc3.xlsx-Sheet1-Supplementary_Table_3_Differentially_expressed_genes_in_CASC11_KD_MHCC-97H_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.16 PDRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92321 KAT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16125 DPP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.322 PCNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43415 OGFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80339 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.203 GOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18984 DCAF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54802 FKTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.2239 ATP11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.26496 Spinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-intersection_DEGs_of_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null H2BC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79144 ART5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40507 TMEM109 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36795 PPM1J CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74689 PMC10925000-12885_2024_12075_MOESM2_ESM.pdf-2-JUNB_JUNB Rummagene Transcription Factor Associations 2026 1.0 null CCNO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13765 Artery - Coronary GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.778137 IDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67982 TRIM68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10868 IGHMBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92427 JPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52311 RBBP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65949 PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null RBMS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59716 NOP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82855 ESPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00622 496100359_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.34804 KIFBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42997 PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.438 USP31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33971 CIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30734 PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null DNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95115 HSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86488 ZNF763 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91784 TAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5902 TBL1XR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46647 AOC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0174 CAMK2N1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4047 OSGEP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43253 ZNF233 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91112 ATP5MGL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33349 PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_1_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null PMC11519470-41467_2024_53624_MOESM1_ESM.pdf-52-TWIST1_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null H1-5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68552 ING2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35527 ERVK3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50502 ATG12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76663 TCF24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13271 ENAH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51182 NFE2L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44222 DGCR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51886 ZNF304 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74218 GH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61544 SERPINB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98646 Vagina GTEx Tissue Gene Expression Profiles 2023 1.0 4.69808 GGA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96437 TBX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68199 SGF29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3686 RUNX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29435 POLD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35854 B4GALT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51999 Lymphatic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.041 C17orf107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27304 C16orf87 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01454 MT-ND4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28111 IGFBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05088 MAMSTR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90632 SCAF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29522 OSBPL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33498 PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null PPP1CC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38576 NR0B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40142 ESRRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38277 ZFP69B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.34106 DESI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40563 Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.083 ZNF341 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70018 MAGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67604 G6PC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33403 ASRGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01882 NUAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60304 ANKRD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45092 SMC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08495 CD2AP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59837 HELLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6043 ELAVL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71096 EFNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96275 WT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21218 WASHC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93155 ZNF277 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36372 SMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98382 HECTD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84278 NTPCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12607 HSPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8463 EHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14153 PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null TACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29384 DHX36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.49576 UGCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82489 BPNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27341 GMPPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74294 NEMF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9128 GAMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58247 AKAP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7566 RNF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7738 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 PYGO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15984 GRHL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19482 AK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90195 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 FJX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3347 SRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5487 HPS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15396 CSNK2A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86025 KLF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32199 H4C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30562 GNG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03775 THAP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52218 CLCN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44025 GFI1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92993 DTX3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84199 ZDHHC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47365 TTLL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47942 RBMY1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.091 SLC35C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08874 APLP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04737 TP53I11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14801 CLASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81809 TPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21026 SLC25A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4549 GSTP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37925 TTC9C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25972 ERGIC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62216 DNAJC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.41909 EVA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85231 NACAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85549 NUP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5868 TRIM17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18328 CEP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61051 HBEGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55319 SSRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92718 PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Supplementary_Table_2F_Contrast_ATF4-def_IGG_8h_vs_HCT116_IGG_8h_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null SLC35A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.06045 Leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 RRBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98689 PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2 Rummagene Transcription Factor Associations 2026 1.0 null CDS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40205 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 TADA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83335 CDK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07411 ZNF439 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47933 COX7A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18978 SLC25A27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90897 PRPSAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4474 PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null PEX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33031 GINS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58825 NHLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53444 PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null RNF185 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85169 CCDC28B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02859 NRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66717 TMEM184C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92719 PSMD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66364 496100401_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.0467 ZNF831 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65867 PMC4677459-NIHMS65392-supplement-Dataset3.xlsx-NFKB1-Unnamed_2_NFKB1 Rummagene Transcription Factor Associations 2026 1.0 null B3GALNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25098 EI24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66064 AMOTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01355 SAMHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9993 HPS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7006 HR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80724 ZNF714 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10606 ABCA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95994 ATP6AP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64522 ATN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37464 TRPC4AP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2479 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_33_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null PCMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30697 PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 BAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16783 PMC8758144-elife-74272-supp3.xlsx-AP2_REP1-GeneName_GTF3A Rummagene Transcription Factor Associations 2026 1.0 null EARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00867 FUS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58472 Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.065 FADS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09092 CHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80528 PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16 Rummagene Transcription Factor Associations 2026 1.0 null FTSJ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14468 PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2 Rummagene Transcription Factor Associations 2026 1.0 null SMIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67912 PMC11239940-44319_2024_164_MOESM1_ESM.pdf-22-LEF1-AS1_LEF1 Rummagene Transcription Factor Associations 2026 1.0 null GPI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96769 FOXA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05467 DGAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49233 PGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54374 CRCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81753 PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_GSEA_state_markers-AP1_JUN Rummagene Transcription Factor Associations 2026 1.0 null SNX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0911 ENY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65098 Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.007 PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR Rummagene Transcription Factor Associations 2026 1.0 null PYM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02779 PLOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53387 KDM6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73208 OTX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51177 CRX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66071 Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.262 LMO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64908 STRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89266 SSBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99245 AXIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41821 LHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43369 PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1 Rummagene Transcription Factor Associations 2026 1.0 null Lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.225 CLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15946 FOXRED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00843 NELFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18391 Alpha thalassemia-X-linked intellectual disability syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 NAPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75783 496100338_HIP_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.35387 IRF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22513 PGAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01588 NAB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15982 MCTS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80843 PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null SNCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25335 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 SP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77759 GPR176 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64395 VRK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22328 PTRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19992 STPG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29764 CLC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17059 G3BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3421 SLC30A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43313 ARG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7088 Lymphatic system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null MORF4L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34164 Central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.095 PLAGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45673 ZNF334 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7893 LCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67369 POLE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31819 TRIM56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86008 TBX15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91655 ZNF613 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6479 GINM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.453 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.151 GTF3C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45707 METTL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5937 TCF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44107 RUBCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17434 PMC11459127-pnas.2406837121.sd04.xlsx-Sheet1-AR_AR Rummagene Transcription Factor Associations 2026 1.0 null ZNF562 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44809 STAT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31086 PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null SCGB3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72848 PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR Rummagene Transcription Factor Associations 2026 1.0 null MBLAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25905 PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null 496100496_FWM_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.2103 CSNK2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22257 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.298 AHCY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97664 PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_13_PDX1 Rummagene Transcription Factor Associations 2026 1.0 null PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 Adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.119 PMC10624900-41467_2023_42825_MOESM13_ESM.xlsx-Module_19-TFAP2B_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null PALM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17928 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_10_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null OXSM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65849 CHMP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55008 CALU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61361 MRPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40652 CCDC177 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11927 USP34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90361 RNF213 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95653 TWNK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40519 ZNF416 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71222 Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 Scoliosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 RAB33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11228 NUDT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27309 PPP1R14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00569 PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4B-Supplemental_Table_S4B_Differentially_expressed_genes_upon_ZFX_Knock_down_in_MCF-7_ZFX Rummagene Transcription Factor Associations 2026 1.0 null ARC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74575 MAJIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71959 SNRPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56577 PLIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0881 PIWIL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04908 PIGQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84171 DTYMK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91609 PMC2813300-pone.0008960.s011.xls-SOX2_targets_in_human_ESCs-Gene_Symbol_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null MED25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19443 FADS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72995 ZNF318 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63888 ZNF528 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60452 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.274 C4orf48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63872 AP3M2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45016 RIMKLB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70275 KIF5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78909 NKX6-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76716 SLTM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10093 496100548_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.0767 ONECUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38701 Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.248 PGBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28769 GMEB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49397 PHOX2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02817 496100407_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08711 Intraocular retinoblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 RTCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94591 ETF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68219 BCAN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14498 MSRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60459 ZSCAN16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15186 AFF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30355 NBN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06686 YPEL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92099 CENPV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24541 CLOCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95777 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.819 NELFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41357 CTNS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72746 SP110 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37212 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null CHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.4215 RPS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40092 496100646_TCx_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.47996 C1orf35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33945 MAP3K14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45406 ZC3H7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72091 SWI5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48808 PMC8758144-elife-74272-supp3.xlsx-AP1_REP2-GeneName_JUN Rummagene Transcription Factor Associations 2026 1.0 null ZNF876P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93129 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_29_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null ERMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79057 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.005 HNF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99249 PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null RIMOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30658 CNOT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82637 TCF20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05139 MIER2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92521 GRINA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37062 SLC7A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03833 Lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.225 Musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 TDRD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16568 ELF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10673 PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Downregulated_NR2F1 Rummagene Transcription Factor Associations 2026 1.0 null PMC7310461__F3 PFOCR Pathway Figure Associations 2024 1.0 null CNIH4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40134 G2E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62523 ACVR2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91231 TOMM40L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64408 DUSP16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44206 Immune system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 CD200 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55404 FAM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12636 PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53 Rummagene Transcription Factor Associations 2026 1.0 null UBALD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87046 SDHAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78443 NRBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37288 TDRD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44102 RGL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78106 HDAC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77886 PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR Rummagene Transcription Factor Associations 2026 1.0 null ATG14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98114 IKZF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09307 Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.112 RTN4RL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36192 TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 PRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94588 TUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56784 NFKB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63827 UFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82697 ADAM15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40635 RAB24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50917 NUDT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95203 CALCOCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39741 RFX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63176 ENSG00000286190 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0636 FAAP24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90451 EEF1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2911 INSR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21522 ZNF587 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.06 TBC1D23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12959 TMEM186 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29394 Extraocular retinoblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 ZNG1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33167 PEPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96664 SLC35B3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34995 CDC37L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68259 RELA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38228 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.007 NBEAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3675 IQSEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63768 ZNF331 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86301 SLC35A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23597 DAZAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89667 CDKN2AIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40793 PMC8120022-CTM2-11-e420-s006.xlsx-Sheet1-Table_S1_786_altered_genes_involved_in_cancer-related_pathway_in_TMPRSS2_ERG_fusion-positive_prostate_cancer_Genes_involed_in_multiple_pathways_are_duplicated_ERG Rummagene Transcription Factor Associations 2026 1.0 null ZNHIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50359 Respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.225 Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205 ANHX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25832 PMC3874167-supp_gkt849_Supplement_Table_S1.xls-DREAM_-_TSS_clearly_affiliated-Gene_name_KCNIP3 Rummagene Transcription Factor Associations 2026 1.0 null FOXS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35934 496100621_TCx_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.15541 TIGD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75784 RTN4IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88166 LRPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38537 BNIP3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42733 GTF3C5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27075 496100319_HIP_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.17633 DPYSL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33538 TUBB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17893 ZNF512 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86881 Connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 SMARCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35456 ATP6V1G1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.924 UBE2V2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34589 ZNF230 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06102 TTPAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61453 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.702 CRNKL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81045 TMEM98 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24459 MARVELD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20317 PALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26339 ZNF154 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48778 GATA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.55676 KMT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34606 C5orf34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39426 ZNF34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5353 POTEF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60589 GPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45851 NRDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15456 MED13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83956 KIT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97601 MORF4L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82037 TCTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85352 TMEM86B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53277 RPRML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50076 PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null CACNG6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60152 PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-x_TFEB_KOcon_VS_WTcon_UP_TFEB Rummagene Transcription Factor Associations 2026 1.0 null PSMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44938 CNIH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79693 STIMATE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97515 MRPS35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90975 PHF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63966 Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 TATDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30294 NKX1-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24709 WWP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89614 TBC1D25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.76973 FAM168B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7005 ZC3H4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50421 MAP2K7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81244 PROCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85179 PIK3R3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05113 COX6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0839 ABHD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5093