association dataset threshold value standardized value outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03398 Myelin sheath COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.784 reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34553 abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.237927 ANP32A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80614 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70382 RHBDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50831 PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null extracellular vesicular exosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.499447 EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null urinary bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.195851 EP300_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE119978,GSE180930_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.850487 BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.32009 CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19242 RBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55584 Perturb_8099_KD_UBE2L3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null WDR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12395 globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.77798 ATF3-27146783-CHIP-SEQ-COLON-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 GTEX-NPJ7-0011-R4a-SM-2I3GJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.12475 H3K9me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8242_KD_SRSF7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.28018 AR-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GNG13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64333 HEL9217 CCLE Cell Line Gene CNV Profiles 1.0 2.71784 DNAJC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55534 SP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32516 ZSCAN9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80728 HOSE cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.763 GSE214382,GSE214383_1_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null Node of Ranvier COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.657 GSE154074_2_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null LC1SQ DepMap CRISPR Gene Dependency 1.0 2.08613 WDR82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56877 Anterior cingulate area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.46486 Primary motor area, Layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61923 GSE154074_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92767 NCIH196 CCLE Cell Line Gene CNV Profiles -1.0 -1.99331 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.857284 Autism DisGeNET Gene-Disease Associations 1.0 null RCC 786-O cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.909 Perturb_8088_KD_FMR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.57816 GSE101239_4_v_1_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.04259 GTEX-Q2AG-0011-R7A-SM-2HMJP GTEx Tissue Sample Gene Expression Profiles 1.0 1.12558 MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37118 p3hr1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.895 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_8132_KD_EIF4A3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SLC19A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08714 RCC-AB COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7791-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Glucose metabolism disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.428 establishing GeneRIF Biological Term Annotations 1.0 null prostate GeneRIF Biological Term Annotations 1.0 null CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null os-rc-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.00652 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10303 Isocortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03774 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GN-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.476201 COG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01352 cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.269 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47254 Perturb_8181_KD_XPO5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.68242 Perturb_8222_KD_AKAP8L_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.2311 GSE67266_7_v_3_etoposide_mouse RummaGEO Drug Perturbation Signatures -1.0 null cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.972195 CCNQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80697 neurological speech impairment HPO Gene-Disease Associations 1.0 null TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71849 Astrocyte_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null GTEX-XLM4-0011-R7A-SM-4AT5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.03683 YWHAE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79824 HCC1187 CCLE Cell Line Gene Expression Profiles 1.0 2.13765 GSE148066,GSE157787_5_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.727 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.913163 Globus pallidus, internal segment Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16219 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15595 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null bartter disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.46466 ZNF333 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19761 rostral ventrolateral reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13179 SH3GLB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69872 antiproliferative GeneRIF Biological Term Annotations 1.0 null ZNF730 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0564 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Down Syndrome DisGeNET Gene-Disease Associations 1.0 null MZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0095 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2207 Perturb_8286_KD_DDX28_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.06833 Organ system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 orbital frontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.916137 GSE210580_0_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F7_E2F7 Rummagene Transcription Factor Associations 2026 1.0 null cuneate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03616 spinalcordupper BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.873018 aplasia/hypoplasia involving the central nervous system HPO Gene-Disease Associations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148252_1_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null cause GeneRIF Biological Term Annotations 1.0 null PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null superficial gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53878 GTEX-RNOR-2326-SM-2TF4I GTEx Tissue Sample Gene Expression Profiles 1.0 0.898413 Perturb_8120_KD_SF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.39352 GSE161800_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05581 Canavan disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.791 external segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22993 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.745 inhibit GeneRIF Biological Term Annotations 1.0 null Diffuse Spongiform Leukoencephalopathy DisGeNET Gene-Phenotype Associations 1.0 null ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.926143 GSE197342_1_v_0_berberine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Brain - Spinal cord (cervical c-1) GTEx Tissue Gene Expression Profiles 2023 1.0 1.98921 Lung squamous cell carcinoma_LUSC_TCGA-39-5030-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute disseminated encephalomyelitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 amygdaloid complex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03907 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.871116 OS-RC-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.97 SPZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2995 Perturb_8158_KD_HNRNPLL_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.3053 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03307 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.85262 Spinal cord disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.333 GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles 1.0 1.16159 Nucleus of the lateral lemniscus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31058 GTEX-XLM4-0011-R9A-SM-4AT45 GTEx Tissue Sample Gene Expression Profiles 1.0 0.97171 GYS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81237 hsa-miR-4697-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Copula pyramidis, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23114 protein localization to cell-cell junction GO Biological Process Annotations 2025 1.0 null Perturb_1100_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles 1.0 0.945056 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X585-0011-R4B-SM-46MVH GTEx Tissue Sample Gene Expression Profiles 1.0 0.954582 GTEX-QMR6-0011-R4A-SM-32PKU GTEx Tissue Sample Gene Expression Profiles 1.0 1.09666 SREK1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23408 Perturb_8147_KD_KRR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.95746 breast carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.371847 GPR153 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82721 CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ7-0011-R5a-SM-33HBK GTEx Tissue Sample Gene Expression Profiles 1.0 1.19765 TCF7L2 ENCODE Transcription Factor Targets 1.0 null layer 2 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39401 P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_8144_KD_PABPC4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.83759 Cerebrovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 GSE100464,GSE100465_0_v_3_atrx_mouse RummaGEO Gene Perturbation Signatures 1.0 null cellular protein localization GO Biological Process Annotations 2015 1.0 null Neuroepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.944 WM88 CCLE Cell Line Gene CNV Profiles -1.0 -2.2573 Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14094 astroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.87782 EP300 ChEA Transcription Factor Targets 1.0 null Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.193 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13935 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05205 extracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.499447 PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GSE234767,GSE234769_3_v_4_cocaine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE218060_7_v_3_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null VPS33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03458 cell-cell contact zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.328332 cognitive impairment GWASdb SNP-Phenotype Associations 1.0 0.658236 nucleus of diagonal band Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.851876 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 OV7 DepMap CRISPR Gene Dependency 1.0 2.03825 NCIH1876 CCLE Cell Line Gene Expression Profiles -1.0 -1.53076 KP1N DepMap CRISPR Gene Dependency 1.0 2.77626 ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.49006 HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838871 hsa-miR-4461 TargetScan Predicted Conserved microRNA Targets 1.0 0.274552 STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STEAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79738 Small Intestine - Terminal Ileum GTEx Tissue Gene Expression Profiles 2023 1.0 2.07608 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.468824 Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.751 Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Piriform-amygdalar area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39304 central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 abnormality of skeletal morphology HPO Gene-Disease Associations 1.0 null SCAND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29496 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.366 GTEX-XOTO-0011-R3A-SM-4B64W GTEx Tissue Sample Gene Expression Profiles 1.0 0.879914 inner CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27943 SNU349 DepMap CRISPR Gene Dependency 1.0 2.94872 AGRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95411 GTEX-N7MT-0011-R10A-SM-2I3E1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.93624 Internode TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.103 connection GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pleated septate junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.141 GSE159728,GSE159730_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null TP53_01_10 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59258 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847959 Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUDHL8 DepMap CRISPR Gene Dependency 1.0 2.52777 first GeneRIF Biological Term Annotations 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.466111 Perturb_8345_KO_EDEM3_SRP251113 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.44365 slow progression HPO Gene-Disease Associations 1.0 null EIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88651 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.013 MARVELD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19434 VAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34217 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46603 SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RET_mutant_23_GDS3319 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.02237 membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.055982 adipose tissue GTEx Tissue Gene Expression Profiles 1.0 1.00859 GSE150349_0_v_1_msx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null KU812 DepMap CRISPR Gene Dependency 1.0 10.2532 peroxisome LOCATE Predicted Protein Localization Annotations 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.977838 Digestive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HT-29 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4445 TargetScan Predicted Conserved microRNA Targets 1.0 0.165047 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PPM1K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10884 Lobule III, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75142 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22784 Perturb_8279_KD_ZNF622_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.9648 breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.175679 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.23676 Electrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.651 pace of progression HPO Gene-Disease Associations 1.0 null Oculodentodigital dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.412 ARVCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97977 CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0011-R1A-SM-3DB7E GTEx Tissue Sample Gene Expression Profiles 1.0 0.845242 LONRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31427 Cerebral degeneration DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 5.0 SW948 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_9818_KD_GATA3_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.60179 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TET1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31397 outer SZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0009 H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null needed GeneRIF Biological Term Annotations 1.0 null SLC25A19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27732 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.91715 Perturb_15098_KD_PDHA1_SRP385600 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.92502 Perturb_3813_KO_Cftr_SRP067491 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -15.0086 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE127790_10_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-N7MT-0011-R7a-SM-2I3FZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.12787 liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.42589 hsa-miR-4640-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHF20L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40485 cellular GeneRIF Biological Term Annotations 1.0 null Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.401 vitamin c_homo sapiens_gpl570_gse11919 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null UBE2Q2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40836 GTEX-R55E-0011-R5A-SM-2TC5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.28451 Medial longitudinal fasciculus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.785 CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null upper dorsal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08477 hsa-miR-4782-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.056784 GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.071 EME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06658 NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10075 Perturb_8170_KD_HNRNPAB_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.34329 CREB3L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2066 epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.500398 CAKI1 DepMap CRISPR Gene Dependency 1.0 2.13979 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07507 AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.169805 GSE101239_4_v_2_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null Retrosplenial area, lateral agranular part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50498 MPZL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.388 system GeneRIF Biological Term Annotations 1.0 null Basolateral amygdalar nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17468 H3K27me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28477 carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.170789 GTEX-QDT8-0011-R5A-SM-32PKN GTEx Tissue Sample Gene Expression Profiles 1.0 1.43406 GTEX-NPJ8-0011-R4a-SM-2HML3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41313 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.062605 Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.064 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Transitional cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.243 cleavage GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-7525-01A-31R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null Bladder Neoplasm DisGeNET Gene-Disease Associations 1.0 null Slow Progression DisGeNET Gene-Phenotype Associations 1.0 null clumsiness HPO Gene-Disease Associations 1.0 null BL41 CCLE Cell Line Gene Expression Profiles 1.0 1.40883 fasciola cinerea Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18303 Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.41172 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04733 Perturb_8175_KD_PNPT1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.88301 SLC35E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12272 primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50242 liver HPA Tissue Protein Expression Profiles 1.0 1.63587 GSE210580_3_v_2_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Infectious mononucleosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.852 ZNF32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63099 ST14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59268 suggested GeneRIF Biological Term Annotations 1.0 null KOPN8 CCLE Cell Line Gene Expression Profiles 1.0 1.44727 PCYT1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25427 PMC9250250__F5 PFOCR Pathway Figure Associations 2024 1.0 null Motor Delay DisGeNET Gene-Phenotype Associations 1.0 null KYSE-510 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5027-01A-21R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE200839,GSE233826_5_v_4_tnrc18_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-NPJ7-0011-R1a-SM-3GACT GTEx Tissue Sample Gene Expression Profiles 1.0 0.94843 Perturb_8186_KD_DNAJC21_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.871116 ChIP_TBX3_20139965 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Myelin membrane TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.416 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE164505,GSE164506_3_v_1_indisulam_human RummaGEO Drug Perturbation Signatures 1.0 null CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 18565887-TableA8 GeneSigDB Published Gene Signatures 1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.85122 SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.986286 TP53-23651856-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-QVUS-0011-R6A-SM-3GACX GTEx Tissue Sample Gene Expression Profiles 1.0 1.20834 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ULK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67725 internal granular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61027 tccb GeneRIF Biological Term Annotations 1.0 null HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -3.2104 liver_d HPA Tissue Sample Gene Expression Profiles 1.0 1.20676 HDAC2 ENCODE Transcription Factor Targets 1.0 null Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.04 Perturb_8228_KD_KIF1C_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.62568 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.283 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37118 Autoimmune disease of peripheral nervous system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.443 CTCF ENCODE Transcription Factor Targets 1.0 null GTEX-N7MT-0011-R4a-SM-2I3G9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28149 Hereditary Nonpolyposis Colorectal Cancer DisGeNET Gene-Disease Associations 1.0 null dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19963 CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126127_5_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MIAPACA2 CCLE Cell Line Gene Expression Profiles -1.0 -2.36274 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.059282 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.679 regulation of biological process GO Biological Process Annotations 2015 1.0 null NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.85338 Ataxia DisGeNET Gene-Phenotype Associations 1.0 null Perturb_8183_KD_DDX1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.5975 Adult Glioblastoma DisGeNET Gene-Disease Associations 1.0 null carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.740915 PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3 Rummagene Transcription Factor Associations 2026 1.0 null macromolecule localization GO Biological Process Annotations 2015 1.0 null GTEX-NL4W-0011-R6a-SM-2I3GA GTEx Tissue Sample Gene Expression Profiles 1.0 1.23907 HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null Orbital area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87622 cytoplasmic GeneRIF Biological Term Annotations 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.707961 A101D CCLE Cell Line Gene Expression Profiles 1.0 1.86465 Anterior cingulate area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79798 incoordination HPO Gene-Disease Associations 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null kidney cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.18113 dorsal part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11952 examined GeneRIF Biological Term Annotations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.638676 PHACTR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47187 digestive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.415434 Muscle Hypotonia DisGeNET Gene-Phenotype Associations 1.0 null NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1489 amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.973759 MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.044306 Congenital nervous system abnormality DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 SN12C COSMIC Cell Line Gene Mutation Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null occipital lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Perturb_8141_KD_MAGOH_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.72189 GSE207301,GSE207303_1_v_2_tp53bp2_human RummaGEO Gene Perturbation Signatures 1.0 null Maple syrup urine disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.19 H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HUH7 CCLE Cell Line Gene Expression Profiles -1.0 -1.86556 mantle zone of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20195 hsa-miR-4733-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23517 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Urinary bladder cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.293 RCOR1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null Secondary motor area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.86783 GSE226316_11_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8124_KD_CCAR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.55663 Pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.695 GTEX-X261-0011-R10B-SM-4E3JT GTEx Tissue Sample Gene Expression Profiles 1.0 0.894174 Cyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.23 Perturb_9821_KD_MYB_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.03369 hsa-miR-520d-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 DYNLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49745 GTEX-S7PM-0011-R6A-SM-3NM8F GTEx Tissue Sample Gene Expression Profiles 1.0 1.07265 Cortical amygdalar area, posterior part, lateral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08986 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05076 Cerebellar Ataxia DisGeNET Gene-Phenotype Associations 1.0 null C3A CCLE Cell Line Gene Expression Profiles 1.0 2.65491 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6255_KO_CIC_ERP108370 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 abnormal axial skeleton morphology HPO Gene-Disease Associations 1.0 null H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE148252_1_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null Perturb_8344_KD_KHSRP_SRP250831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.44783 BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46722 MM160113 DepMap CRISPR Gene Dependency 1.0 3.66669 SNU886 CCLE Cell Line Gene CNV Profiles -1.0 -1.63899 GTEX-WZTO-0011-R4A-SM-3NMC7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.927746 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenal gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.187 CORL24 CCLE Cell Line Gene Expression Profiles -1.0 -1.45444 Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88678 abnormality of the cerebral white matter HPO Gene-Disease Associations 1.0 null SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78988 GSE210580_3_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE123958,GSE123959_0_v_1_mta1_human RummaGEO Gene Perturbation Signatures 1.0 null Encephalomyelitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.651 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.760137 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958459 Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65675 CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8152_KD_TBRG4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.174 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Secondary motor area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.49308 PMC3568013-1471-2105-13-128-S6.xls-NME2-Unnamed_1_NME2 Rummagene Transcription Factor Associations 2026 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XLM4-0011-R2B-SM-4AT5Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.930582 GOLGA6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38285 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.972559 plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE57875_1_v_0_hnrnpl_mouse RummaGEO Gene Perturbation Signatures 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-4539 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 PCDHB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81188 HNF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36517 ej cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.978917 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VILL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3517 retardation GeneRIF Biological Term Annotations 1.0 null Perturb_8537_KO_Notch2_SRP152804 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.9067 CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59979 axon GO Cellular Component Annotations 2023 1.0 null MBD4_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null mental GeneRIF Biological Term Annotations 1.0 null intermediate stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16219 muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.062116 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.008 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07495 r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47337 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7537 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15595 H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null uroepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.191557 Lung squamous cell carcinoma_LUSC_TCGA-96-A4JK-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KATOIII CCLE Cell Line Gene CNV Profiles 1.0 1.58442 spinal cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.818994 hippocampus (hippocampal formation)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.90987 GSE210580_0_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04312 inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08801 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.10501 ANKRD17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57371 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z2-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Potassium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.086 PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_8191_KD_ILF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.8734 hepacam GeneRIF Biological Term Annotations 1.0 null hsa-miR-1255a TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 YY1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null silencing GeneRIF Biological Term Annotations 1.0 null SLC25A27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90897 2-hydroxyglutaric aciduria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.174 CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063668 GTEX-T6MN-0011-R2A-SM-32QOW GTEx Tissue Sample Gene Expression Profiles 1.0 0.880397 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-1266 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null LCN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07215 NCIH1105 CCLE Cell Line Gene Expression Profiles -1.0 -2.74731 GTEX-X4XX-0011-R3B-SM-46MWK GTEx Tissue Sample Gene Expression Profiles 1.0 1.10891 Urinary bladder carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.854 hsa-miR-3146 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 EBV-B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.556 exosome (rnase complex) COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.499042 biological_process GO Biological Process Annotations 2015 1.0 null Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10076 PMC4172779-13048_2014_87_MOESM1_ESM.pdf-145-C9orf90_NAIF1 Rummagene Transcription Factor Associations 2026 1.0 null E2A MotifMap Predicted Transcription Factor Targets 1.0 null breast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.089254 cell-cell junction GO Cellular Component Annotations 2025 1.0 null Perturb_8262_KD_RPS5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.94302 Fast muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.975 zonal layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44367 reticular nucleus of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44031 GSE226316_1_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE199092_1_v_0_ddx5_human RummaGEO Gene Perturbation Signatures -1.0 null intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.858815 tumorigenesis GeneRIF Biological Term Annotations 1.0 null Perturb_8075_KD_AATF_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.503 CARMIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05381 bounding membrane of organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.054699 Reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.646 Intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.598 ARID3A ENCODE Transcription Factor Targets 1.0 null hsa-miR-4423-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.436802 caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21526 Perturb_8142_KD_MATR3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.80778 SUPHD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.4706 seizures HPO Gene-Disease Associations 1.0 null GTEX-N7MT-0011-R6a-SM-2I3G3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.42503 ovary GTEx Tissue Gene Expression Profiles -1.0 -0.875678 striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07134 HAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52291 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.963609 ataxia HPO Gene-Disease Associations 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.922632 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 hsa-miR-370 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28112 layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.01989 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE223008_5_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59154 GTEX-X4XX-0011-R2A-SM-3P623 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18494 CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ACHN cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.997 abnormality of the skull HPO Gene-Disease Associations 1.0 null Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75142 RAD21_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH526 CCLE Cell Line Gene Expression Profiles -1.0 -1.46246 ATAD3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00567 diffuse swelling of cerebral white matter HPO Gene-Disease Associations 1.0 null Perturb_8113_KD_U2AF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.7917 Septate junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.931 TP53-23651856-MEF-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null cysts GeneRIF Biological Term Annotations 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.564 Transitional Cell Carcinoma Of Bladder DisGeNET Gene-Disease Associations 1.0 null GSE182680,GSE182683_0_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null C6orf132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84766 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01906 Perturb_8100_KD_ABCF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 ZNF264 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08064 H3K4ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.146 PMC12480273-12672_2025_3611_MOESM1_ESM.xlsx-csgene-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null BBm cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.545 membrane region COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.094002 ectopic GeneRIF Biological Term Annotations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.85505 Brain myelin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.315 H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-KLF5_targets-target_gene_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null GSE210580_3_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OXRO-0011-R9A-SM-3NB1X GTEx Tissue Sample Gene Expression Profiles 1.0 0.841789 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.960525 Axolemma COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.561 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23384 organelle LOCATE Predicted Protein Localization Annotations 1.0 null UROD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77299 WWP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89614 abnormality of brain morphology HPO Gene-Disease Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null astrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.89817 primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.988495 substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12904 GOLGA6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41229 Deutocerebrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.242 cerebral lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 MTDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8829 GTEX-QDT8-0011-R4A-SM-32PKM GTEx Tissue Sample Gene Expression Profiles 1.0 1.43 layer 4 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72031 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04322 regulation of growth GO Biological Process Annotations 2015 1.0 null PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null renal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.633169 Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50394 FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null A375SKINCJ3 DepMap CRISPR Gene Dependency 1.0 2.22645 Hypothalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.175 CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.682 PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1 Rummagene Transcription Factor Associations 2026 1.0 null r4 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2323 renal carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.617486 GSE89057_0_v_1_sox5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE92457_9_v_12_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_8112_KD_SUPT6H_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.46024 GTEX-T5JC-0011-R5A-SM-32PLK GTEx Tissue Sample Gene Expression Profiles 1.0 1.05651 Carcinoma Of Bladder DisGeNET Gene-Disease Associations 1.0 null NCI-H1869 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of hindbrain morphology HPO Gene-Disease Associations 1.0 null Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null SEPTIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9302 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8207_KD_RAVER1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.20234 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055779 Aicardi-Goutieres syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.153 EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE218060_1_v_6_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null dorsolateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20223 Epilepsy HuGE Navigator Gene-Phenotype Associations 1.0 null KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10006 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.54455 CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Carcinogenesis DisGeNET Gene-Phenotype Associations 1.0 null GTEX-NPJ7-0011-R2a-SM-2I3GF GTEx Tissue Sample Gene Expression Profiles 1.0 1.27803 Perturb_8162_KD_SNRNP70_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.27036 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19406 LAMB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25125 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.922632 TKKK DepMap CRISPR Gene Dependency 1.0 2.39917 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.58723 GTEX-RVPU-0011-R3A-SM-2XCAE GTEx Tissue Sample Gene Expression Profiles 1.0 1.08068 Hypomyelinating leukodystrophy 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.193 HNF4A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10006 GTEX-TSE9-0011-R6A-SM-3DB7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.990165 nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044639 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null glial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.97285 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03509 A673 DepMap CRISPR Gene Dependency 1.0 3.18116 TBX3 ChEA Transcription Factor Targets 1.0 null NCIH524 CCLE Cell Line Gene Expression Profiles -1.0 -1.53597 atrophy/degeneration affecting the central nervous system HPO Gene-Disease Associations 1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Tooth agenesis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.221 hsa-miR-655 TargetScan Predicted Conserved microRNA Targets 1.0 0.303626 Follicular dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.717 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PLEKHG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57965 Perturb_11382_KD_NKX25_SRP152523 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.9556 GTEX-NL3H-0011-R6a-SM-2I3G8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20987 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.182454 GTEX-QDT8-0011-R1A-SM-32PKS GTEx Tissue Sample Gene Expression Profiles 1.0 1.36626 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.960874 outer SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.78724 corpus callosum TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 control GeneRIF Biological Term Annotations 1.0 null GTEX-N7MS-0011-R6a-SM-2HMJ4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.983921 Non-Small Cell Lung Carcinoma DisGeNET Gene-Disease Associations 1.0 null GSE210580_0_v_2_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH1105 CCLE Cell Line Gene CNV Profiles 1.0 1.79918 GSE221577_4_v_5_pik3r1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXA1_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-0011-R3A-SM-3GIK8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.839625 H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null u-373mg cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.540188 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.963336 Adrenoleukodystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.231 PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_8193_KD_PPIL4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.70581 CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE119978,GSE180930_3_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE241402_0_v_1_prmt5_human RummaGEO Gene Perturbation Signatures 1.0 null lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.83833 abnormal oligodendrocyte physiology MGI Mouse Phenotype Associations 2023 1.0 null mantle zone of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18056 hsa-miR-4286 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07748 H2BK15ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040734 GSE258991_1_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.063374 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Electric organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.789 type ii diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.82634 Myelin sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.315 inhibits GeneRIF Biological Term Annotations 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.922632 HEC151 CCLE Cell Line Gene Expression Profiles 1.0 1.55459 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.878856 cerebral cortex HPA Tissue Protein Expression Profiles 1.0 1.013 negative regulation of biological process GO Biological Process Annotations 2015 1.0 null DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE80098,GSE80366_0_v_8_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-NPJ7-0011-R10A-SM-2I3E5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26736 GSE198971_0_v_2_ncor2_mouse RummaGEO Gene Perturbation Signatures 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null Perturb_8050_KD_METTl14_SRP167173 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.64263 IGROV1 DepMap CRISPR Gene Dependency 1.0 3.26147 Perturb_8107_KD_FIP1L1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.2757 Fibre tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.46 Megalencephalic leukoencephalopathy with subcortical cysts 2B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.776 GTEX-PWO3-0011-R1A-SM-2I5EW GTEx Tissue Sample Gene Expression Profiles 1.0 1.28352 GSE142684_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06521 GSE111881_0_v_1_znf768_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RU72-0011-R6A-SM-2TF71 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23537 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52054 POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4170_KO_Atp1a2_SRP248220 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.696 LRRC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23599 CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATP5F1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46715 GSE223008_9_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_7day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.79521 hsa-miR-124 TargetScan Predicted Conserved microRNA Targets 1.0 0.187098 MYC ENCODE Transcription Factor Targets 1.0 null central lateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20959 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.931517 Renal Cell Carcinoma DisGeNET Gene-Disease Associations 1.0 null CEBPB_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Large For Gestational Age DisGeNET Gene-Phenotype Associations 1.0 null MM485 DepMap CRISPR Gene Dependency 1.0 2.23802 PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OXRO-0011-R10A-SM-2I5EH GTEx Tissue Sample Gene Expression Profiles 1.0 1.04944 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.842413 Perturb_16822_KD_Miat_SRP379156 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.844387 Urinary bladder cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.854 regulatory GeneRIF Biological Term Annotations 1.0 null primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00871 GSE163862_1_v_3_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89221 H3K27me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ependymal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.297806 central GeneRIF Biological Term Annotations 1.0 null parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3972 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in rostral cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.864975 CCK81 DepMap CRISPR Gene Dependency 1.0 4.51615 glycosylation GeneRIF Biological Term Annotations 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EW-12 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S7PM-0011-R5A-SM-3NM8G GTEx Tissue Sample Gene Expression Profiles 1.0 1.04528 posteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08515 Perturb_8276_KD_UPF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.26153 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.919606 Lung squamous cell carcinoma_LUSC_TCGA-22-4599-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null brain_a HPA Tissue Sample Gene Expression Profiles 1.0 1.66606 CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.721 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX Rummagene Transcription Factor Associations 2026 1.0 null cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.608663 GSE138672_0_v_1_rabgef1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nervous system disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 5.0 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30175 brain cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065456 hsa-miR-371b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OV90 DepMap CRISPR Gene Dependency 1.0 3.49312 GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06941 Prelimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06673 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10993 megalencephalic leukoencephalopathy with subcortical cysts 2a OMIM Gene-Disease Associations 1.0 null only GeneRIF Biological Term Annotations 1.0 null GSE127790_4_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8257_KD_RBM27_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.5525 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Orthogonal array COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.132 extracellular GeneRIF Biological Term Annotations 1.0 null Perturb_9690_KO_RNASEH2B_SRP355094 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.44169 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.37211 Ribonuclease H2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.598 RELCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2816 HEK-293A cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.708 abnormal astrocyte morphology MGI Mouse Phenotype Associations 2023 1.0 null Perturb_8196_KD_TIAL1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.95764 SBF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80218 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.888632 MECP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.602 Perturb_10353_KO_Hbb_SRP333852 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.35844 GRINA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52737 TAF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05205 mantle zone of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00666 Fra-1_KO_GDS5078_402_mouse_Lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SDCBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11762 Male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.068 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE98898_4_v_1_hoxa1_human RummaGEO Gene Perturbation Signatures -1.0 null Astrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.405 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.977547 UBC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31806 Perturb_8206_KD_PRPF6_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.64318 phenotype GeneRIF Biological Term Annotations 1.0 null Autistic Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Krabbe disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 promote GeneRIF Biological Term Annotations 1.0 null renal cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.652589 hsa-miR-544b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GSE185163_5_v_2_clic4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.212 cell-cell junction GO Cellular Component Annotations 2015 1.0 null extracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.13137 FOXA2 ENCODE Transcription Factor Targets 1.0 null periventricular stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22417 TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.939099 GTEX-NL4W-0011-R4a-SM-2I5GZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.09635 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35505 CTCF_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.16825 Breast cancer (survival) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.9 MB21D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65918 PLPPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79447 COLO678 CCLE Cell Line Gene CNV Profiles 1.0 1.39932 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE92457_9_v_10_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.897954 inner CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.85001 Perturb_5104_KO_Ythdc1/Dux_SRP251747 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.79716 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8195_KD_SMN1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.39443 liver HPA Tissue Gene Expression Profiles 1.0 1.07016 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.97099 GSE159446,GSE159449_1_v_0_tunicamycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null methylphenidate_mus musculus_gpl11180_gse33619 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null motility GeneRIF Biological Term Annotations 1.0 null cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null D542MG DepMap CRISPR Gene Dependency 1.0 4.5835 GSE87615_2_v_3_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null Leukoencephalopathy with vanishing white matter DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.691 H3K18ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Diabetes mellitus DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.428 cav1 GeneRIF Biological Term Annotations 1.0 null HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.89018 telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-PVOW-0011-R1A-SM-32PL6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.830014 GTEX-T6MN-0011-R4A-SM-32QPG GTEx Tissue Sample Gene Expression Profiles 1.0 1.02393 PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null habenula (old epithalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11551 abnormality of the musculature HPO Gene-Disease Associations 1.0 null CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE122215,GSE122217_0_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null MOB1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1121 ventrolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0736 nucleus sagulum, deep part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1612 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34825 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5124 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.972559 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Copula pyramidis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14874 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20566 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40219 transitional cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.865999 GSE223008_7_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_8129_KD_DDX3X_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.16211 CTCF_astrocyte of the spinal cord_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver Carcinoma DisGeNET Gene-Disease Associations 1.0 null LRRC10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37977 astrocyte projection GO Cellular Component Annotations 2025 1.0 null r3 part of parvicellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01698 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2064 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-25-MYBL2_MYBL2 Rummagene Transcription Factor Associations 2026 1.0 null neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.062543 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09782 interferongamma GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inward rectifying potassium channel COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.902 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Hypomyelinating leukodystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.784 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.875185 Bladder transitional cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.338 GTEX-TSE9-0011-R10A-SM-3DB7O GTEx Tissue Sample Gene Expression Profiles 1.0 1.06898 NFIC ENCODE Transcription Factor Targets 1.0 null basolateral amygdaloid nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25355 Perturb_8336_KD_CTNNB1_SRP213717 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 contribute GeneRIF Biological Term Annotations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5013636-ncomms12601-s5.xlsx-LEF1-Groups_LEF1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T5JC-0011-R2A-SM-32PLZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.00778 GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45365 ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0776 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Multiple sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.045 GTEX-NPJ7-0011-R8a-SM-2I3G2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.899326 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QMR6-0011-R2A-SM-32PKV GTEx Tissue Sample Gene Expression Profiles 1.0 1.11077 hsa-miR-1255b TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 POLR2A ENCODE Transcription Factor Targets 1.0 null Perturb_8109_KD_MSI2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.23349 Perturb_1088_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.40374 outer SZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.987577 renal GeneRIF Biological Term Annotations 1.0 null autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.460883 lipid GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23725 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19242 ARHGEF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30083 HIF1A_01_220 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.78353 H2BC21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77795 RAB9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69167 Gizzard smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.938 GTEX-T5JC-0011-R9A-SM-32PLV GTEx Tissue Sample Gene Expression Profiles 1.0 1.21184 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.880721 nuclear membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.17687 ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.0348 GTEX-T6MN-0011-R7A-SM-32QP5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03572 mcf-7 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.407832 GSE210373_0_v_1_cntnap4_human RummaGEO Gene Perturbation Signatures -1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11568 abnormality of the skeletal system HPO Gene-Disease Associations 1.0 null GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_8138_KD_IGF2BP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5677 NFIC_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8080_KD_DDX24_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.4522 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Astrocyte end-foot COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.489 Perturb_8083_KD_FASTKD2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.8039 extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.159462 truncation GeneRIF Biological Term Annotations 1.0 null PMC7762487__F8 PFOCR Pathway Figure Associations 2023 1.0 null Cerebral white matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.398 Diffuse White Matter Abnormalities DisGeNET Gene-Disease Associations 1.0 null Cranial nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.447 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8135_KD_G3BP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_8146_KD_HSPD1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.95871 Perturb_5054_KO_Adnp_SRP104194 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.95426 cell-cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 PDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4981 TREX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90668 SMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1784 localization GO Biological Process Annotations 2015 1.0 null Disease of anatomical entity DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 5.0 Perturb_8084_KD_CELF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14514 GTSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.454 PMC7762487__F8 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-N7MS-0011-R2a-SM-2HML6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.967549 SNU466 CCLE Cell Line Gene Expression Profiles 1.0 1.97139 PMC8554124-DataSheet2.XLSX-34-RFX3_RFX3 Rummagene Transcription Factor Associations 2026 1.0 null layer 3 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33434 D425 DepMap CRISPR Gene Dependency 1.0 2.9005 Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.116 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.476 paraventricular nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31506 diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.321252 TBC1D13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41185 chr11_124921026_C_A_b38 GTEx eQTL 2025 1.0 1.83319 hepatocytes GeneRIF Biological Term Annotations 1.0 null Progressive Neurologic Deterioration DisGeNET Gene-Phenotype Associations 1.0 null FLI1 ChEA Transcription Factor Targets 1.0 null multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8202 Perturb_8081_KD_EIF3G_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.7758 KLHDC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.32471 hsa-miR-508-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.072324 mRNA_NR2F2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSPA1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30301 Axon initial segment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.011 H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FXR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68729 Stomach TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.193 Perturb_11440_KO_RB1/TP53_SRP253428 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.58869 HEV_60Day_None_GSE53731 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.42947 CHP126 CCLE Cell Line Gene CNV Profiles -1.0 -1.59067 spasticity HPO Gene-Disease Associations 1.0 null GSE138945,GSE138947_0_v_1_mboat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47699 GTEX-Q2AG-0011-R6A-SM-2HML7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20252 GSE216757_4_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_8154_KD_CPSF6_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 red nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23939 Paranodal junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.97 MAGOHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26018 Subventricular zone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.298 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.12082 CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null adhesion GeneRIF Biological Term Annotations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.929131 KMS12BM CCLE Cell Line Gene Expression Profiles 1.0 1.43216 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r5 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03774 protein localization GO Biological Process Annotations 2015 1.0 null Adrenal cortical hypofunction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.122 GSE137177_2_v_0_folic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null CALU6 CCLE Cell Line Gene Expression Profiles 1.0 1.44204 GTEX-R55E-0011-R9A-SM-2TC6C GTEx Tissue Sample Gene Expression Profiles 1.0 1.11251 brain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 abnormal myelin sheath morphology MGI Mouse Phenotype Associations 2023 1.0 null Perturb_8300_KD_AUH_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12056 necessary GeneRIF Biological Term Annotations 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TRIM41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89181 Perturb_8323_KD_INO80_SRP103083 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.59655 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12387 Perturb_8200_KD_FUBP3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.28749 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.844676 Perturb_8091_KD_NOL12_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Dystroglycan complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.897 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64049 CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HK2 CCLE Cell Line Gene Expression Profiles 1.0 1.38278 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14344 GSE142684_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null neuron part GO Cellular Component Annotations 2015 1.0 null ERVK3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50502 TE15 CCLE Cell Line Gene Expression Profiles -1.0 -1.8654 REST-18959480-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCIH526 CCLE Cell Line Gene CNV Profiles 1.0 2.17876 PTPN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39246 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.93786 r11 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23194 encodes GeneRIF Biological Term Annotations 1.0 null GSTP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87093 CEBPD ENCODE Transcription Factor Targets 1.0 null H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cerebellar disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.274 Perturb_13601_KD_YAP1_SRP337871 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.4307 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Meninx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.493 abnormality of forebrain morphology HPO Gene-Disease Associations 1.0 null differentiation GeneRIF Biological Term Annotations 1.0 null GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.24493 GTEX-QMR6-0011-R5A-SM-32PKT GTEx Tissue Sample Gene Expression Profiles 1.0 1.18807 hsa-miR-4722-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.020071 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.940123 GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles 1.0 1.01724 ROCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39457 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044404 Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NL3H-0011-R5a-SM-2I3GB GTEx Tissue Sample Gene Expression Profiles 1.0 1.27754 CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Childhood Glioblastoma DisGeNET Gene-Disease Associations 1.0 null Superior colliculus, zonal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.06432 GSE162892_3_v_2_isox_human RummaGEO Drug Perturbation Signatures 1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.542566 t-24 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.906256 Perturb_8180_KD_STIP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.10922 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40967 Prostate disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.062 Cerebral Ventriculomegaly DisGeNET Gene-Phenotype Associations 1.0 null primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12235 JUND ENCODE Transcription Factor Targets 1.0 null H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Myotonia congenita DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.34 GTEX-RU72-0011-R5A-SM-2TF6U GTEx Tissue Sample Gene Expression Profiles 1.0 1.33538 urothelial GeneRIF Biological Term Annotations 1.0 null whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.900903 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39287 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.93942 Schwann cell microvillus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.834 VASP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92707 Regio parietalis capitis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.293 GTEX-X261-0011-R7A-SM-4E3JJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.924425 upregulation GeneRIF Biological Term Annotations 1.0 null GTEX-QDT8-0011-R7A-SM-32PKF GTEx Tissue Sample Gene Expression Profiles 1.0 1.21733 Perturb_6253_KO_CIC_ERP108370 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 FOXA1 ENCODE Transcription Factor Targets 1.0 null GSE119978,GSE180930_6_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_8166_KD_CNOT7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 negative regulation of cellular process GO Biological Process Annotations 2015 1.0 null oligodendrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.347408 Primary motor area, Layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.13527 leukodystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.31275 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles 1.0 1.0221 Astroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.404 GSE207301,GSE207303_0_v_3_tp53bp2_human RummaGEO Gene Perturbation Signatures 1.0 null Female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.646 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.546533 TCF21-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MT-0011-R2a-SM-2I3GI GTEx Tissue Sample Gene Expression Profiles 1.0 1.19555 superficial stratum of FCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38527 GM2 gangliosidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0591 apparent GeneRIF Biological Term Annotations 1.0 null SERPINE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41446 VSIG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67989 primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.57847 layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07969 High grade glioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 X-linked recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.252 GSE211983_0_v_2_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Basal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.844 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null dorsal endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1907 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0011-R1A-SM-2HMJI GTEx Tissue Sample Gene Expression Profiles 1.0 1.00848 CCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84334 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.026054 ROS50 DepMap CRISPR Gene Dependency 1.0 3.88965 CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WVLH-0011-R5A-SM-3MJFW GTEx Tissue Sample Gene Expression Profiles 1.0 1.2313 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14344 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0385 lowlevel GeneRIF Biological Term Annotations 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18013 Neuron projection membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.544 SELENON CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60743 GTEX-RU72-0011-R9A-SM-2TF67 GTEx Tissue Sample Gene Expression Profiles 1.0 0.841096 Renal cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.381 GTEX-N7MS-0011-R7a-SM-2HMKN GTEx Tissue Sample Gene Expression Profiles 1.0 0.932532 Perturb_4317_KO_Fmn2_SRP109283 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.6255 Lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.1 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04973 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.295 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SUM185PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.759948 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.835287 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.999909 AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60428 hsa-miR-570 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Perturb_14013_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 hsa-miR-4726-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 1.43394 ZNF692 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96087 LAPTM4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57302 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53309 bladder carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.899924 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null less GeneRIF Biological Term Annotations 1.0 null Perturb_8133_KD_EIF4B_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.91297 Inward rectifier potassium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.059 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null PMC9334851__F1 PFOCR Pathway Figure Associations 2024 1.0 null Astrocyte_Brain_Human CellMarker Gene-Cell Type Associations 1.0 null Sarcoma_SARC_TCGA-SI-A71P-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inferior frontal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.656 MUS81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13617 glia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.967225 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX Rummagene Transcription Factor Associations 2026 1.0 null PIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66409 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0861 Bladder disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.283 PATU8902 CCLE Cell Line Gene CNV Profiles 1.0 1.3371 vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.055089 sirolimus_homo sapiens_gpl2895_gse16944 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20743 496100438_PCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.43417 Perturb_8056_KD_IGF2BP1_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_8086_KD_EIF4G1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 nuclear outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.591812 Astrocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.644 Perturb_8225_KD_DKC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.199 Perturb_9820_KD_LMO1_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.10502 cerebral degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.18152 GTEX-NL3H-0011-R4a-SM-2I3GK GTEx Tissue Sample Gene Expression Profiles 1.0 1.16221 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00164 hypertonia HPO Gene-Disease Associations 1.0 null Allan-Herndon-Dudley syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.261 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886256 layer 3 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92899 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20379 CDIPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71672 LN340 DepMap CRISPR Gene Dependency 1.0 4.27412 PRPF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28571 zona incerta, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.878938 Leukodystrophy DisGeNET Gene-Disease Associations 1.0 null PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE148066,GSE157787_3_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 0.908036 GSE185519_3_v_7_gilteritinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mutant GeneRIF Biological Term Annotations 1.0 null GTEX-NL3H-0011-R7a-SM-2I3G5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06382 chaperone GeneRIF Biological Term Annotations 1.0 null Internal capsule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.561 NCIH1436 CCLE Cell Line Gene Expression Profiles -1.0 -2.22103 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAF-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Cerebral amyloid angiopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.059 Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.6706 GSE214514_1_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Leading edge membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.507 Hepatobiliary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 Muscle Spasticity DisGeNET Gene-Phenotype Associations 1.0 null urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.05242 EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.425514 POLR1F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3381 Mild Mental Retardation DisGeNET Gene-Disease Associations 1.0 null Cavum septum pellucidum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.712 LRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2312 GTEX-QVJO-0011-R5A-SM-2S1QM GTEx Tissue Sample Gene Expression Profiles 1.0 1.16411 H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF3/E2A-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE211241_1_v_0_runx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC366 CCLE Cell Line Gene CNV Profiles 1.0 1.99785 autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.487407 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.246 Lobule II, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27421 abnormality of the metencephalon HPO Gene-Disease Associations 1.0 null HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24875 presents GeneRIF Biological Term Annotations 1.0 null H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126345_4_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB134VI CCLE Cell Line Gene CNV Profiles -1.0 -1.40751 496100496_FWM_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.47616 Prostate adenocarcinoma_PRAD_TCGA-J4-A83K-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34867 GTEX-XOTO-0011-R1B-SM-4B65C GTEx Tissue Sample Gene Expression Profiles 1.0 1.01213 GTEX-R55E-0011-R8A-SM-2TC66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08502 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.03907 A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.36474 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68855 head TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Perturb_8359_KD_HNF4a_SRP365071 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.10886 GTEX-TSE9-0011-R7A-SM-3DB7P GTEx Tissue Sample Gene Expression Profiles 1.0 0.98825 ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.3033 membrane part GO Cellular Component Annotations 2015 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Occipital lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.322 Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Endoplasmic reticulum quality control compartment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.88 H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE205332_1_v_0_queuine_human RummaGEO Drug Perturbation Signatures -1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12844 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Asperger syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.448 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 temporal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 astroglial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.890525 LRFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24042 COIL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22744 central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.520731 TE4 CCLE Cell Line Gene CNV Profiles -1.0 -1.43728 GTEX-RNOR-0011-R9A-SM-2TF52 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28133 MTMR14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75913 Perturb_8072_KD_SNORD126_SRP337208 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.11696 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33071 kidney cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.166686 COV504 CCLE Cell Line Gene Expression Profiles -1.0 -1.6621 GSE119978,GSE180930_2_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null HARA CCLE Cell Line Gene CNV Profiles 1.0 2.79325 Perturb_8085_KD_DAZAP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 hsa-miR-4260 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU1544 DepMap CRISPR Gene Dependency 1.0 2.56279 cerebral atrophy HPO Gene-Disease Associations 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.51219 GSE146687_2_v_5_eribulin_human RummaGEO Drug Perturbation Signatures 1.0 null YAP_OE_GDS3220_32_human_MCF10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PL21 CCLE Cell Line Gene Expression Profiles -1.0 -1.50591 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1993 DepMap CRISPR Gene Dependency 1.0 3.57344 Perturb_6257_KO_CIC_ERP108370 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Secondary motor area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02591 GTEX-XLM4-0011-R3B-SM-4AT6E GTEx Tissue Sample Gene Expression Profiles 1.0 1.21817 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.919606 L33 CCLE Cell Line Gene CNV Profiles -1.0 -1.60414 TCEAL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55393 GTEX-P44H-0011-R5A-SM-2XCEX GTEx Tissue Sample Gene Expression Profiles 1.0 1.17893 Cell envelope Sec protein transport complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.851 PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9 Rummagene Transcription Factor Associations 2026 1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.56044 neuron part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Malignant astrocytoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.237 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Temporal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.816 carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.37687 CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17552 Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.897251 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31988 posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.6111 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hydrocephalus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040613 CMK86 CCLE Cell Line Gene CNV Profiles 1.0 1.74415 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.967324 HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenal adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.03 WDR26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30413 mitochondrial membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.064186 superficial stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50817 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.75302 Megalencephalic leukoencephalopathy with subcortical cysts 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.303 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.88824 EIF4E2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98274 macrocephaly GeneRIF Biological Term Annotations 1.0 null IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00714 medial habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42646 CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null D423MG DepMap CRISPR Gene Dependency 1.0 4.33293 intact GeneRIF Biological Term Annotations 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850301 SLC25A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56754 substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.65463 Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04227 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.255567 dystrophin-associated glycoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.589 GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 1.51367 EMB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44225 abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.097167 EXOC3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49826 Pathologic nystagmus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.076 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.4634 GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.14647 Cerebral gray matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.618 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8009 dorsolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.84127 astrocytoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.084537 GSE213746_0_v_1_kdm5b_mouse RummaGEO Gene Perturbation Signatures 1.0 null GA10 CCLE Cell Line Gene Expression Profiles 1.0 1.39693 Perturb_9817_KD_E2A_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.5535 central medullary reticular group, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.934624 WM983B CCLE Cell Line Gene CNV Profiles -1.0 -2.57193 X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45129 Superior colliculus, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64726 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_8250_KD_LSM11_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.50546 Astrocyte projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.928 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.83475 Perturb_8367_KD_IGF2BP1_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Retrosplenial area, lateral agranular part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13597 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.588 musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045901 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07709 rcc 786-o cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.36268 abnormality of muscle physiology HPO Gene-Disease Associations 1.0 null GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 0.915826 Perturb_8221_KD_ACO1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.0374 Seizures DisGeNET Gene-Phenotype Associations 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054845 Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.026 SDHAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57387 GSE81803,GSE81912_3_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4699-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 GSE149880_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null renal cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.77857 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.115883 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.4712 report GeneRIF Biological Term Annotations 1.0 null Kidney cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.349 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0393 EBF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92505 GSE119498_0_v_7_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RNOR-0011-R7A-SM-2TF4V GTEx Tissue Sample Gene Expression Profiles 1.0 0.826494 GTEX-X4XX-3026-SM-3NMB2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04975 HCC827GR5 CCLE Cell Line Gene Expression Profiles 1.0 1.7913 hsa-miR-29a TargetScan Predicted Conserved microRNA Targets 1.0 0.15008 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.217 H3K23ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null layer 3 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10979 GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 0.87144 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.4905 GSE139016_3_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XMD1-0011-R10A-SM-4AT4A GTEx Tissue Sample Gene Expression Profiles 1.0 1.13908 TMEM175 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92331 GTEX-QDT8-0011-R3A-SM-32PKR GTEx Tissue Sample Gene Expression Profiles 1.0 1.52241 GATA1-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-S7SE-0011-R10A-SM-2XCDF GTEx Tissue Sample Gene Expression Profiles 1.0 0.824895 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64893 Oligodendrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.303 brain GTEx Tissue Gene Expression Profiles 1.0 2.18944 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NASP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28812 Neoplasm Metastasis DisGeNET Gene-Phenotype Associations 1.0 null TPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25222 EAST syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.442 LSS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25209 Perturb_8137_KD_HNRNPK_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.2218 GSE210580_3_v_1_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null iglike GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2704-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null ZNF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18285 CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NSMCE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33054 Lobules IV-V, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94423 mRNA_SMAD4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mouth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.056 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126345_7_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_4327_KO_Zcchc8_SRP187429 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.61432 internal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05318 Perturb_8212_KD_SMNDC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.98806 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Subarachnoid space TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.737 resulting GeneRIF Biological Term Annotations 1.0 null GSE109140_0_v_1_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13216 Perturb_4203_KO_Fmr1_SRP075646 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.59418 MYBL2 ENCODE Transcription Factor Targets 1.0 null UNC13D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96322 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null relapsing-remitting multiple sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.712 UBE2D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17068 Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.942212 Neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.404 all GWASdb SNP-Phenotype Associations 1.0 0.032793 GTEX-OXRN-2426-SM-2I5EQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.32517 HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.40471 AKIRIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46594 ZNF771 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84775 Ion channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.035 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Astroglial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.403 RIPK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48191 GSE216523_1_v_0_ptpmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Astrocyte end-foot COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01565 primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.64463 GTEX-Q2AG-0011-R9A-SM-2HMJ6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05088 Dysarthria DisGeNET Gene-Disease Associations 1.0 null H3K27me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null U-373MG cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.023 VAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7818 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01163 Frontal pole, cerebral cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.34046 Perturb_8111_KD_STAU1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.485 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.72233 ZNF845 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96376 GTEX-NL4W-0011-R5a-SM-2I3GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.3422 Syntrophin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.461 macrocephaly HPO Gene-Disease Associations 1.0 null Lobule III Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72501 cellular localization GO Biological Process Annotations 2015 1.0 null HLE CCLE Cell Line Gene Expression Profiles 1.0 1.74683 hsa-miR-1914 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Oral hairy leukoplakia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.36 Myelinating Schwann cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.781 GTEX-UTHO-0011-R1A-SM-3GIJO GTEx Tissue Sample Gene Expression Profiles 1.0 0.943856 BEX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06264 TE159T CCLE Cell Line Gene Expression Profiles 1.0 1.88965 Spinal cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.386 cell cycle process GO Biological Process Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Amyotrophic lateral sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.266 Ovary TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.646 CREB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6924 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2228 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.878234 CDC42SE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61871 gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.210253 superficial stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13155 cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74323 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null Perturb_2901_KD_HDAC1_SRP327853 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 AKAP17A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64976 hcc GeneRIF Biological Term Annotations 1.0 null superficial stratum of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33468 LARP4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69795 increased brain size MGI Mouse Phenotype Associations 2023 1.0 null H3K27me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE196110_1_v_2_ndrg3_mouse RummaGEO Gene Perturbation Signatures 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the cerebral subcortex HPO Gene-Disease Associations 1.0 null POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anaplasmosis_Leukemic Cell_GSE2600 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 0.96507 GSE88819_11_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210580_0_v_1_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XLM4-0011-R4B-SM-4AT5C GTEx Tissue Sample Gene Expression Profiles 1.0 1.2259 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1966 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.939099 Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H727 COSMIC Cell Line Gene CNV Profiles 1.0 2.15316 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.01431 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042711 ITGB1BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52854 ventrolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20269 cell part GO Cellular Component Annotations 2015 1.0 null H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WL46-0011-R5A-SM-3LK6V GTEx Tissue Sample Gene Expression Profiles 1.0 0.956355 PLTP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94477 Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.051 LRRC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9286 GTEX-PWO3-0011-R5A-SM-2I5EZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.42252 GTEX-WZTO-0011-R1B-SM-3NMAR GTEx Tissue Sample Gene Expression Profiles 1.0 1.15272 X-linked monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.287 ZNF502 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71715 TEAD4 ENCODE Transcription Factor Targets 1.0 null FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null p21waf1 GeneRIF Biological Term Annotations 1.0 null Sphingolipidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.175 mantle zone of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23194 Perturb_8182_KD_ADAR_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.4064 H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0316 chr11_124944386_A_T_b38 GTEx eQTL 2025 1.0 1.93543 LPCAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81917 ALG13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06482 Primary motor area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40088 cognitive impairment HPO Gene-Disease Associations 1.0 null GTEX-T5JC-0011-R1A-SM-32PM6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.854873 Chl TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.607 Hyperactive Behavior DisGeNET Gene-Phenotype Associations 1.0 null GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11238 GSE227891_2_v_0_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null molecular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51609 Astrocyte projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 LGR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36066 GSE220600_1_v_2_clpp_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE221577_2_v_0_pik3r1_human RummaGEO Gene Perturbation Signatures 1.0 null Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25637 GSE138468_3_v_6_dyrk1a_mouse RummaGEO Gene Perturbation Signatures -1.0 null functions GeneRIF Biological Term Annotations 1.0 null Megalencephalic leukoencephalopathy ClinVar Gene-Phenotype Associations 2025 1.0 null anion GeneRIF Biological Term Annotations 1.0 null Perturb_8209_KD_RPS10_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.33506 fat_x1.V2 HPA Tissue Sample Gene Expression Profiles 1.0 1.26504 STAT3 ENCODE Transcription Factor Targets 1.0 null GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.891885 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.042015 GTEX-Q2AG-0011-R5A-SM-2HMJH GTEx Tissue Sample Gene Expression Profiles 1.0 1.28441 Dystrobrevin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.446 GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 0.933694 hepg2 GeneRIF Biological Term Annotations 1.0 null Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.193 Urinary bladder cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.38 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847959 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46307 Orbital area, medial part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.18747 DISP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52616 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null Tectum mesencephali TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.702 RANBP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17834 Perturb_8074_KO_LDB1_SRP327786 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.25503 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.837329 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06757 ALDOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56273 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.703 Congenital nystagmus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 LMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.65476 outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13777 hsa-miR-29c TargetScan Predicted Conserved microRNA Targets 1.0 0.154935 abnormality of higher mental function GWASdb SNP-Phenotype Associations 1.0 0.267786 TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null Retrosplenial area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23765 Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.39176 PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_8_MSC Rummagene Transcription Factor Associations 2026 1.0 null Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.963 Perturb_8184_KD_DHX30_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE82104,GSE82299_1_v_0_acriflavine_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_8077_KD_CSTF2T_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.39613 PRKACB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76862 Lung squamous cell carcinoma_LUSC_TCGA-98-A53A-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210580_4_v_1_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.569222 HS294T CCLE Cell Line Gene Expression Profiles 1.0 2.25276 Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05749 CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64129 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.836197 LNCAP-C4-2B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.619 abnormality of the nervous system HPO Gene-Disease Associations 1.0 null layer 5 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2087 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886256 pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.407919 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76214 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.644 Conventional (Clear Cell) Renal Cell Carcinoma DisGeNET Gene-Disease Associations 1.0 null abnormality of the cerebellum HPO Gene-Disease Associations 1.0 null PPP4R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80306 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01655 superficial stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11346 H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cmyc GeneRIF Biological Term Annotations 1.0 null H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bladder transitional cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.646505 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08609 thomsen disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.817976 abnormality of the head HPO Gene-Disease Associations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LMCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19843 HNF4G ENCODE Transcription Factor Targets 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10381 GSE210580_5_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48011 C1QL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21239 GSE200673,GSE200691_2_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ventrolateral prefrontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.848181 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.728 cerebral edema MGI Mouse Phenotype Associations 2023 1.0 null TALDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86495 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46722 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UTX-26944678-CHIP-SEQ-JUKART-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8376 hepn1 GeneRIF Biological Term Annotations 1.0 null Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67832 mantle zone of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10597 Perturb_8261_KD_RPS2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.3934 GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 1.23993 dominant GeneRIF Biological Term Annotations 1.0 null GTEX-S7SE-0011-R1A-SM-2XCDE GTEx Tissue Sample Gene Expression Profiles 1.0 0.893064 Neural arch TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.916 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.935469 GSE162892_3_v_2_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WWYW-0011-R7A-SM-3NB3H GTEx Tissue Sample Gene Expression Profiles 1.0 0.959625 H3K27me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_8054_KD_IGF2BP1_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.44394 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.512564 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.032862 relationship GeneRIF Biological Term Annotations 1.0 null HT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34122 HNF4G_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46603 H2810 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.214017 Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.667 Perturb_8258_KD_RCC2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.4927 GSE130246_2_v_3_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null OCILY10 CCLE Cell Line Gene CNV Profiles -1.0 -1.43442 cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.179459 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null protein localization to cell junction GO Biological Process Annotations 2025 1.0 null Axonal growth cone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.757 GSE184210_0_v_1_glucagon_mouse RummaGEO Drug Perturbation Signatures 1.0 null TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null Microcephaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.099 Cataract 37 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069 KU812 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pelizaeus-Merzbacher disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.717 HS746T COSMIC Cell Line Gene Mutation Profiles 1.0 null Ovarian Diseases CTD Gene-Disease Associations 1.0 1.29502 H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_17305_KD_Chrm1_SRP222274 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.382 RPRML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50076 GTEX-WVLH-0011-R7A-SM-3MJFB GTEx Tissue Sample Gene Expression Profiles 1.0 1.10086 r11 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1978 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00133 GTEX-WVLH-0011-R6A-SM-3MJFZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.18538 Perturb_14749_KO_MEOX2_SRP330486 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 periventricular stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01551 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null FAM3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59431 ZFP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14469 outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.132113 XBP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8957 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KE39 CCLE Cell Line Gene CNV Profiles 1.0 1.66085 MOLT16 CCLE Cell Line Gene Expression Profiles 1.0 2.40871 Perturb_8106_KD_ESF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.66945 GSE163862_2_v_3_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null NCIH2066 CCLE Cell Line Gene Expression Profiles -1.0 -1.63824 mode of inheritance HPO Gene-Disease Associations 1.0 null RNF187 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70543 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.31006 GTEX-Q2AG-0011-R8A-SM-2HMK5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.986108 VPS33A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31214 PGBD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36879 GTEX-QDT8-2926-SM-32PKC GTEx Tissue Sample Gene Expression Profiles 1.0 1.4249 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bladder GeneRIF Biological Term Annotations 1.0 null H2AK5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20208 H3K27me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null outer SZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.920272 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.65186 CSNK2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12549 cellecm GeneRIF Biological Term Annotations 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-ND-A4WF-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nuclear outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.771 frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.953423 GSE126345_2_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10993 FOXP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79554 Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22179 Glioblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.24 BBC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44711 cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45421 cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26502 Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89768 PSMD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32488 megalencephaly HPO Gene-Disease Associations 1.0 null GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50898 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04995 TMEM181 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03732 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-QMR6-0011-R1A-SM-32PKW GTEx Tissue Sample Gene Expression Profiles 1.0 1.05491 GSE135400_1_v_0_kdm1b_human RummaGEO Gene Perturbation Signatures 1.0 null KMT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38019 brain_3b HPA Tissue Sample Gene Expression Profiles 1.0 1.82008 rostral migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23846 Immunoglobulin subtype 2 InterPro Predicted Protein Domain Annotations 1.0 null Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 GSE60837_2_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null Gap junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.919 Retrosplenial area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02151 CMK115 DepMap CRISPR Gene Dependency 1.0 7.05663 MBD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal glial cell physiology MGI Mouse Phenotype Associations 2023 1.0 null Perturb_8190_KD_HNRNPU_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.77672 arrest GeneRIF Biological Term Annotations 1.0 null H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SUSD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95858 GSE115542_5_v_4_digoxin_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CMK115 CCLE Cell Line Gene CNV Profiles 1.0 1.95557 primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0769 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.06325 GTEX-WL46-0011-R2A-SM-3LK6O GTEx Tissue Sample Gene Expression Profiles 1.0 0.850517 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958741 GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 0.828852 NCIH2073 CCLE Cell Line Gene CNV Profiles -1.0 -1.79524 Diffuse Swelling Of Cerebral White Matter DisGeNET Gene-Phenotype Associations 1.0 null Perturb_8349_KD_MACROH2A1/MACROH2A2_SRP293365 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.05356 REM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14913 Alexander disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.049 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FGF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45021 Perturb_227_KO_Pet1_SRP194283 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 renal tubular transport disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.209248 glioblastoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.098182 H2AB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14457 hippocampus (hippocampal formation)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3673 mantle zone of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38527 GSE119978,GSE180930_3_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null STK38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97623 ORMDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43218 cytoskeleton GeneRIF Biological Term Annotations 1.0 null TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0168 RBBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77478 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08609 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19668 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70529 RHBDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29851 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 0.850476 Cell projection membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.237 GTEX-WZTO-0011-R7B-SM-4E3IS GTEx Tissue Sample Gene Expression Profiles 1.0 1.11627 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42068 GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.866305 transitional cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.636785 Paranode region of axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.833 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.007 GSE126127_2_v_1_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.654221 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09802 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.269335 GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.471 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02632 Spleen GTEx Tissue Gene Expression Profiles 2023 1.0 1.36412 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, barrel field, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30155 GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 0.972884 Perturb_8334_KD_HCF1_SRP178073 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.24921 Liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NL4W-0011-R10A-SM-2I3DY GTEx Tissue Sample Gene Expression Profiles 1.0 1.10508 neuron projection GO Cellular Component Annotations 2015 1.0 null GTEX-UTHO-0011-R2A-SM-3GIKC GTEx Tissue Sample Gene Expression Profiles 1.0 0.895241 Large_Intestine-monocyte Tabula Sapiens Gene-Cell Associations 1.0 1.91671 CYB5R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18763 Perturb_8230_KD_PUS1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null cell-cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE210580_4_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.161 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.873718 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFE2L2_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null Somatomotor areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91117 effect GeneRIF Biological Term Annotations 1.0 null Prelimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21394 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22288 Perturb_8219_KD_XRCC6_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.32543 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.895843 case GeneRIF Biological Term Annotations 1.0 null GSE239898,GSE239899_1_v_2_hiltonol_human RummaGEO Drug Perturbation Signatures 1.0 null external cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30611 Ependymocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.404 NCIH929 CCLE Cell Line Gene CNV Profiles 1.0 1.71284 brain cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076049 MTF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8986 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.443 Nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.267 SSBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9576 GSE142684_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Clumsiness - Motor Delay DisGeNET Gene-Disease Associations 1.0 null Perturb_8234_KD_NELFE_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NBPF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75641 GTEX-WVLH-0011-R4A-SM-3MJFS GTEx Tissue Sample Gene Expression Profiles 1.0 1.2449 Gas bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.603 GSE209928_0_v_1_kmt2b_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-N7MT-0011-R5a-SM-2I3G6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.43094 PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null ERBB2_knockdown_234_GSE8373 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.78544 Transitional cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.628 GTEX-WZTO-0011-R5B-SM-3NMC5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14785 H2BK20ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.569622 outer CP in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.940816 GTEX-R55E-0011-R7A-SM-2TC5Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.26575 SU-DHL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43446 BPH cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.879 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null STK26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17161 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15408 ULBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64885 CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Macrocephaly DisGeNET Gene-Disease Associations 1.0 null GSE109285_3_v_2_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null Lobule III, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7151 PRDM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94743 RL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05582 SNU761 CCLE Cell Line Gene CNV Profiles -1.0 -2.02159 Perturb_8134_KD_FXR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.6929 GTEX-P44H-0011-R1A-SM-3NM8J GTEx Tissue Sample Gene Expression Profiles 1.0 1.17322 NCIH1573 CCLE Cell Line Gene CNV Profiles 1.0 1.60543 Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXH1-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67067 PITX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66928 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886256 leukoencephalopathy GeneRIF Biological Term Annotations 1.0 null B95-8 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.662 Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NJ-01A-22R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23027 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040763 STAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55882 RNF40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00259 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.983543 BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12844 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.5736 GTEX-X261-0011-R5A-SM-3NMB4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24525 neuron projection GO Cellular Component Annotations 2023 1.0 null ERBB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5018 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847322 GSE92457_7_v_8_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_8122_KD_SNRNP200_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.44238 Hypomyelinating leukodystrophy 19 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.334 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0647 GSE236486_1_v_0_arnt_human RummaGEO Gene Perturbation Signatures -1.0 null GSE196671_5_v_0_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063131 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.862391 PMC12041165-401_2025_2886_MOESM1_ESM.xlsx-Meta_CAA_vs_AD-Genes_TSHZ1 Rummagene Transcription Factor Associations 2026 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24537 GTEX-X4XX-0011-R6B-SM-46MWP GTEx Tissue Sample Gene Expression Profiles 1.0 1.35493 breast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.294223 L-2-hydroxyglutaric aciduria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 GTEX-R55G-2426-SM-2TC5I GTEx Tissue Sample Gene Expression Profiles 1.0 0.884575 GTEX-QDT8-0011-R8A-SM-32PKE GTEx Tissue Sample Gene Expression Profiles 1.0 1.63753 GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 1.15866 hsa-miR-3661 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Subcommissural organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.737 GSE249714_0_v_1_anxa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 0.897176 GSE126345_2_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.999422 Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04544 layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09371 carcinogenesis GeneRIF Biological Term Annotations 1.0 null GSE119978,GSE180930_2_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XOTO-0011-R9A-SM-4GICI GTEx Tissue Sample Gene Expression Profiles 1.0 0.995824 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19213 AP2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39062 physical GeneRIF Biological Term Annotations 1.0 null abnormality of skull size HPO Gene-Disease Associations 1.0 null Dendritic branch COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.916 IGR39 DepMap CRISPR Gene Dependency 1.0 3.11317 PMC8421368-41598_2021_97059_MOESM3_ESM.xlsx-Genesets-GSC_GSC Rummagene Transcription Factor Associations 2026 1.0 null DAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57298 Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16614 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.965337 Macroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.419 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Renal cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.075 neurodevelopmental delay HPO Gene-Disease Associations 1.0 null P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-QVJO-0011-R6A-SM-2S1QN GTEx Tissue Sample Gene Expression Profiles 1.0 1.16947 estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-QVUS-0011-R9A-SM-3GIJA GTEx Tissue Sample Gene Expression Profiles 1.0 0.929088 anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.84099 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.865112 LPAR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05882 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE189653,GSE203344_2_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null extracellular region part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04751 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Glial cell projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 biological adhesion GO Biological Process Annotations 2015 1.0 null Immunoglobulin-like fold InterPro Predicted Protein Domain Annotations 1.0 null Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92198 frontal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 MCCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08087 Cardiomyocyte_Atrium_Human CellMarker Gene-Cell Type Associations 1.0 null GSE109140_2_v_3_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null Torsion dystonia 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.344 GSE227891_5_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null partially GeneRIF Biological Term Annotations 1.0 null oligodendroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.32205 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.06325 Jacobsen Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.608 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8F_Het1A-GATA6_2d_5x_closed-Gene_Name_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RU72-0011-R7A-SM-2TF5U GTEx Tissue Sample Gene Expression Profiles 1.0 1.0305 superficial stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38527 GTEX-XOTO-0011-R6B-SM-4B65X GTEx Tissue Sample Gene Expression Profiles 1.0 1.0324 adipose tissue HPA Tissue Gene Expression Profiles 1.0 1.1218 nerve GTEx Tissue Gene Expression Profiles 1.0 0.981296 Vermal regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56116 HS604T CCLE Cell Line Gene Expression Profiles 1.0 1.63399 primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23349 GTEX-RVPV-0011-R3A-SM-2TF63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14664 TMEM201 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67941 GTEX-T6MN-2626-SM-32PMQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.847384 Perturb_8076_KD_AGO1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.10661 TAF1 ENCODE Transcription Factor Targets 1.0 null Inhibitory synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.271 MDAMB436 CCLE Cell Line Gene Expression Profiles -1.0 -1.77902 Diencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.175 affects GeneRIF Biological Term Annotations 1.0 null such GeneRIF Biological Term Annotations 1.0 null Dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 GTEX-QVJO-0011-R2A-SM-2S1QK GTEx Tissue Sample Gene Expression Profiles 1.0 1.1972 GTEX-T6MN-0011-R5A-SM-32QPD GTEx Tissue Sample Gene Expression Profiles 1.0 1.14394 GSE119978,GSE180930_6_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.99342 GSE152050,GSE152052_1_v_0_arid1a_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE115542_2_v_4_digoxin_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30766 RFX5 ENCODE Transcription Factor Targets 1.0 null Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.116 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.988495 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3889 proper GeneRIF Biological Term Annotations 1.0 null Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6224 TRAPPC6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37116 Subacute sclerosing panencephalitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 ABCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61281 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0858 OVMANA DepMap CRISPR Gene Dependency 1.0 2.44457 Neuromyelitis optica DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.508 inner CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14519 GTEX-NPJ8-1526-SM-2D7VU GTEx Tissue Sample Gene Expression Profiles 1.0 1.36187 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.9741 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Necrosis CTD Gene-Disease Associations 1.0 1.06844 GTEX-NPJ8-0011-R1a-SM-33HCB GTEx Tissue Sample Gene Expression Profiles 1.0 0.894649 GTEX-N7MT-0011-R8a-SM-2I5GU GTEx Tissue Sample Gene Expression Profiles 1.0 0.83649 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.317503 Perturb_6502_KO_SOCS3_SRP168556 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.66499 organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.063546 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.900462 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.948873 lateral septal nucleus, intermediate part, periventricular Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05425 MM253 DepMap CRISPR Gene Dependency 1.0 2.76377 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null biological GeneRIF Biological Term Annotations 1.0 null Prelimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.27805 CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41825 urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.00794 PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null A-CA-04-2009(H1N1)_3Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.57786 CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rett syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.061 TTC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89672 Parotid acinar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.544 CEMIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81972 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.660304 Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reexpression GeneRIF Biological Term Annotations 1.0 null Contagious pustular dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.076 MTMR11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73603 Optic nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.449 brain HPA Tissue Gene Expression Profiles 1.0 1.77338 hsa-miR-4436b-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.078844 NALM6 DepMap CRISPR Gene Dependency 1.0 2.39179 KPNA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10501 GTEX-QVJO-0011-R4A-SM-2S1QL GTEx Tissue Sample Gene Expression Profiles 1.0 1.39437 CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles 1.0 0.964635 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE203060_0_v_2_kdm4c_human RummaGEO Gene Perturbation Signatures -1.0 null FAHD2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.029 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063373 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.09958 Lobules IV-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95027 nucleus sagulum, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48011 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847959 H3K27me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28271 GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 0.959935 hsa-miR-4725-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 0.846181 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HT55 DepMap CRISPR Gene Dependency 1.0 2.74444 ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1613 SMC3 ENCODE Transcription Factor Targets 1.0 null GSE122215,GSE122217_0_v_2_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-NPJ8-0011-R10A-SM-2YUMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.22451 HNF4A ENCODE Transcription Factor Targets 1.0 null lateropallial amygdalopiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56544 Perturb_8260_KD_RPLP0_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE119978,GSE180930_0_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.901994 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.891145 zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05033 CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null phase GeneRIF Biological Term Annotations 1.0 null GM2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39734 ARHGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22357 parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.918135 CEBPB_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1287 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.302118 GTEX-XOTO-0011-R5A-SM-4B657 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1481 Centrum semiovale TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.763 GSE113106_2_v_1_dnm2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE221577_3_v_5_pik3r1_human RummaGEO Gene Perturbation Signatures 1.0 null DDX19B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27055 cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59337 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.878234 GTEX-XOTO-3026-SM-4B65M GTEx Tissue Sample Gene Expression Profiles 1.0 1.04827 NPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81711 brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.612011 NR1I2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5326 Myelin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.293 Ensheathing process COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.428 ventrolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3057 GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles 1.0 1.17875 Parietal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.296 DOHH2 CCLE Cell Line Gene Expression Profiles 1.0 1.43627 GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.25348 H2BK120ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null research GeneRIF Biological Term Annotations 1.0 null GSE171311_0_v_1_ellagic acid_human RummaGEO Drug Perturbation Signatures -1.0 null GSE162892_4_v_2_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8280_KD_DDX5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 FGFR1OP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84381 KDM7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34307 CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.954052 Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.228 reactivation GeneRIF Biological Term Annotations 1.0 null cell projection GO Cellular Component Annotations 2015 1.0 null facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.977554 axon COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.434 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29359 SAFB2_02_150 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.73697 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.925987 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.357028 GSE235707,GSE235712_1_v_0_ctbp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenal glomerulosa cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.94 Hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.203 ELK3-25401928-HUVEC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE119498_2_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.902176 Perturb_9081_KD_XBP1_SRP117686 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.00598 GSE102342,GSE102648_1_v_2_curcumin_mouse RummaGEO Drug Perturbation Signatures -1.0 null primary auditory cortex (core)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01414 there GeneRIF Biological Term Annotations 1.0 null astroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.123708 SNU1196 CCLE Cell Line Gene Expression Profiles 1.0 1.44195 Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE225647_1_v_3_srsf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.893865 external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54728 ASB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42224 silenced GeneRIF Biological Term Annotations 1.0 null motor delay HPO Gene-Disease Associations 1.0 null prepontine hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21855 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4619 Urinary bladder transitional cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.63 lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04973 GSE142684_0_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.48997 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.371982 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05336 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31647 F5 CCLE Cell Line Gene Expression Profiles 1.0 1.47407 SKRC20 DepMap CRISPR Gene Dependency 1.0 2.90666 EFO27 CCLE Cell Line Gene Expression Profiles -1.0 -2.60669 POLR2A_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8293_KD_SUPV3L1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-526b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -1.59792 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43446 Central nervous system disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 5.0 mitochondrial part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.051059 GTEX-X4XX-0011-R1B-SM-3P622 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22977 ERCC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02729 Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.35597 cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Mesaxon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.344 SOX11-22085726-ESNS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14779 Addison's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.149 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21472 GSE213228_1_v_0_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null implies GeneRIF Biological Term Annotations 1.0 null isthmic alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36482 FOXA1-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_8232_KD_ZC3H8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.701 Uvula (IX), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16466 cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.269335 GTEX-WHSE-0011-R2A-SM-3P5ZL GTEx Tissue Sample Gene Expression Profiles 1.0 1.04129 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14446 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1601 outer SZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11446 Six3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.6727 CMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07435 KMBC2 DepMap CRISPR Gene Dependency 1.0 2.38155 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.69842 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34884 NANOG-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null vacuolation GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null glioblastoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.094365 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tumor Cell Invasion DisGeNET Gene-Phenotype Associations 1.0 null Mural cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.866 Perturb_14504_KO_Tgfb3_SRP020224 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.2623 Uvula (IX), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26944 single-organism process GO Biological Process Annotations 2015 1.0 null NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8148 ZNF569 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59402 glial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07041 optic fiber layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2527 Renal carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.177 Perturb_8302_KD_RBM22_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SIGLEC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65879 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null Liver GTEx Tissue Gene Expression Profiles 2023 1.0 2.61043 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96533 PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_8204_KD_IGF2BP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Cerebellar ataxia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 GTEX-XOTO-0011-R8A-SM-4B65J GTEx Tissue Sample Gene Expression Profiles 1.0 0.889692 GSE161302,GSE161304_1_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null abnormality of the cerebral ventricles HPO Gene-Disease Associations 1.0 null AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05599 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14174 GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56657 regulation of cellular process GO Biological Process Annotations 2015 1.0 null Autoimmune disease of the nervous system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.025 superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04973 SLC39A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18174 perilemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37458 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.839194 cellular macromolecule localization GO Biological Process Annotations 2015 1.0 null Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urinary bladder cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.2149 GID8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7728 GTEX-PWO3-0011-R3A-SM-2I5EX GTEx Tissue Sample Gene Expression Profiles 1.0 1.2892 myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.064053 extends GeneRIF Biological Term Annotations 1.0 null membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045688 type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.938237 Perturb_8058_KD_IGF2BP1_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30046 SLC35D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22101 close GeneRIF Biological Term Annotations 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11643 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40219 medial intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05737 suggesting GeneRIF Biological Term Annotations 1.0 null upper motor neuron dysfunction HPO Gene-Disease Associations 1.0 null hsa-miR-3616-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.454769 hsa-miR-3065-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 Perturb_8098_KD_TUFM_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.301 bladder transitional cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.62108 Dilated Ventricles (Finding) DisGeNET Gene-Phenotype Associations 1.0 null Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.8692 Progression Of Non-Small Cell Lung Cancer DisGeNET Gene-Disease Associations 1.0 null H3K14ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ES5 DepMap CRISPR Gene Dependency 1.0 3.12422 Glioblastoma DisGeNET Gene-Disease Associations 1.0 null Perturb_8256_KD_RACK1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.5975 Cortical amygdalar area, posterior part, lateral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59967 Orbital area, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04 Infertility, Male CTD Gene-Disease Associations 1.0 1.26359 TARBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57594 NCIH841 DepMap CRISPR Gene Dependency 1.0 3.52061 SOGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68817 Inflammation CTD Gene-Disease Associations 1.0 1.11877 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057955 currents GeneRIF Biological Term Annotations 1.0 null HT CCLE Cell Line Gene CNV Profiles -1.0 -1.61729 KYSE-70 COSMIC Cell Line Gene Mutation Profiles 1.0 null substantia nigra, pars reticulata, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09929 autism GeneRIF Biological Term Annotations 1.0 null GSE151090_2_v_4_verteporfin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE226316_4_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10006 Leukoencephalopathy with vanishing white matter 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.113 GSE148066,GSE157787_11_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CTAGE15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32053 Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73681 T-24 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.937 Disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 5.0 posterior triangular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28414 Epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.942 Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.558 TFAP2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.477 Carcinoma, Transitional Cell DisGeNET Gene-Disease Associations 1.0 null Glial cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.775 PMC3631253__F4 PFOCR Pathway Figure Associations 2024 1.0 null neuron projection COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H4K91ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Compact myelin COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.739 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.931315 cytoplasm GO Cellular Component Annotations 2015 1.0 null gracile nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.47691 interacts GeneRIF Biological Term Annotations 1.0 null Glaucoma_Retina_GSE3554 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.18696 BOK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95923 liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.404931 PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-OLIG2-M_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null GSE261563_9_v_4_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null Tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.433 Corpus callosum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.61 CIZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63529 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH727 CCLE Cell Line Gene CNV Profiles 1.0 1.37255 cerebral white matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.58282 Cerebral Atrophy DisGeNET Gene-Disease Associations 1.0 null GTEX-XMD1-0011-R3B-SM-4AT5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.14193 dorsolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33681 Perturb_11387_OE_OC2_SRP122890 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.75975 PDIA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52974 GTEX-T6MN-0011-R9A-SM-32QOZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.836677 TTC642 DepMap CRISPR Gene Dependency 1.0 4.14782 GSE183327,GSE183328_3_v_0_ddit3_human RummaGEO Gene Perturbation Signatures -1.0 null Status epilepticus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null biu87 GeneRIF Biological Term Annotations 1.0 null glial GeneRIF Biological Term Annotations 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0769 MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.931166 glialcam GeneRIF Biological Term Annotations 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.57212 496100316_TCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.74636 NUP214 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38092 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15515 RLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74771 Orbital area, medial part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80985 Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.243 T47D CCLE Cell Line Gene CNV Profiles 1.0 2.02533 SDHAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79703 axon GO Cellular Component Annotations 2015 1.0 null Mitochondrial electron transfer flavoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.662 GSE173262_2_v_0_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.873718 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16034 OVSAHO CCLE Cell Line Gene CNV Profiles -1.0 -1.92032 hsa-miR-4518 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Frontal pole, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.50238 hsa-miR-488 TargetScan Predicted Conserved microRNA Targets 1.0 0.283838 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.244 ATIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56334 GSE143316_0_v_6_somatostatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_8192_KD_PARN_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.5037 GTEX-T5JC-0011-R10A-SM-32PM2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.865712 GTEX-WHSE-3026-SM-3P5ZH GTEx Tissue Sample Gene Expression Profiles 1.0 1.0776 Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.253 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03371 Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65695 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null isthmus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2847 GSE227891_5_v_0_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null acted GeneRIF Biological Term Annotations 1.0 null GSE113106_2_v_4_dnm2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.90881 OVOL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42741 GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Epstein-Barr virus infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.15 GTEX-NPJ7-2726-SM-2I3FT GTEx Tissue Sample Gene Expression Profiles 1.0 1.41598 Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3689a-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.072324 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.07396 Large Head (Disorder) DisGeNET Gene-Phenotype Associations 1.0 null abnormal muscle tone HPO Gene-Disease Associations 1.0 null transmembrane GeneRIF Biological Term Annotations 1.0 null Motor neuron disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.276 adult-onset leukoencephalopathy with axonal spheroids and pigmented glia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04 CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-939 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 TAF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.667215 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE60837_2_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.17277 ALS2CL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71627 PGGHG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47184 induces GeneRIF Biological Term Annotations 1.0 null hsa-miR-3714 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NH-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ICAM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83792 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARHGDIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99349 SAP30L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91505 neurodevelopmental abnormality HPO Gene-Disease Associations 1.0 null autosomal dominant inheritance HPO Gene-Disease Associations 1.0 null EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Disease of metabolism DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.428 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null vegf GeneRIF Biological Term Annotations 1.0 null mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59394 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860946 Perturb_6437_KD_HDAC1_SRP327853 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.699 CMK CCLE Cell Line Gene CNV Profiles 1.0 1.72494 Perturb_8297_KD_XRN2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.10364 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3127-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.45923 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.966684 ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.84377 Oligodendroglioma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.551 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10944835-41467_2024_46639_MOESM4_ESM.xlsx-SD17-Supplementary_Data_17_Differentially_expressed_genes_according_to_homozygous_genotype_at_the_TWIST1_locus_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null NAT8L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17838 PPTC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9477 suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.003992 ZNF410 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1933 H2BK12ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null B-103 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.764 GTEX-RVPU-0011-R10A-SM-2XCAH GTEx Tissue Sample Gene Expression Profiles 1.0 0.876666 PMC9692021-Table_4.xlsx-Table_S4-Table_S4_405_DEGs_of_RA_synovial_tissues_between_NFIL3-high_and_NFIL3-low_group_NFIL3 Rummagene Transcription Factor Associations 2026 1.0 null PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null layer I of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05226 H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058439 ARHGEF39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79003 Perturb_8128_KD_CIRBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.56197 hepatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.299242 r10 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12826 layer 2 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74324 Nucleus dentatus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.661 Perturb_8304_KD_SSB_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19811 ENTPD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46569 Atherosclerosis CTD Gene-Disease Associations 1.0 1.169 GTEX-QDT8-0011-R10A-SM-32PKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.31077 hsa-miR-587 TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 Orbital area, lateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03254 TCF7L2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEL CCLE Cell Line Gene CNV Profiles 1.0 1.90371 Generalized Hypotonia DisGeNET Gene-Phenotype Associations 1.0 null CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8078_KD_DAZAP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX Rummagene Transcription Factor Associations 2026 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11792 CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-0011-R6A-SM-4AT4B GTEx Tissue Sample Gene Expression Profiles 1.0 1.09905 PTPRZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58808 HCC1143 CCLE Cell Line Gene Expression Profiles -1.0 -1.46704 abnormality of the cerebrum HPO Gene-Disease Associations 1.0 null PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null Chromosomal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.094 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03531 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16875 GTEX-S7SE-0011-R2A-SM-2XCDC GTEx Tissue Sample Gene Expression Profiles 1.0 0.886067 noticeably GeneRIF Biological Term Annotations 1.0 null HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.952793 GTEX-WHSE-0011-R6A-SM-3P5ZP GTEx Tissue Sample Gene Expression Profiles 1.0 1.15069 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LCLC103H CCLE Cell Line Gene CNV Profiles -1.0 -2.07342 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.81746 CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain_3c HPA Tissue Sample Gene Expression Profiles 1.0 1.65716 DCBLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02665 accelerated GeneRIF Biological Term Annotations 1.0 null Perturb_8274_KD_SERBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null cell cycle arrest GO Biological Process Annotations 2015 1.0 null Perturb_8290_KD_PRPF8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.8874 kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.136732 white matter of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22337 Encephalitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.184 GTEX-X261-0011-R6B-SM-4E3J8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.992551 GSE168797_2_v_3_cannabidiol_human RummaGEO Drug Perturbation Signatures -1.0 null NIF3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90755 Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.33618 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-374c TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12272 Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lynch Syndrome DisGeNET Gene-Disease Associations 1.0 null MISP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91172 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.89443 GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles 1.0 1.15412 Renal Carcinoma DisGeNET Gene-Disease Associations 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21745 FASTKD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76406 LHX9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04555 cetuximab_homo sapiens_gpl570_gse21483 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null senescence GeneRIF Biological Term Annotations 1.0 null GSE233679_5_v_11_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null morphological abnormality of the central nervous system HPO Gene-Disease Associations 1.0 null Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.294 CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.900322 SKMEL30 DepMap CRISPR Gene Dependency 1.0 6.8606 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 amygdaloid complex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.917805 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null P3H4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73438 negative regulation of cell cycle GO Biological Process Annotations 2015 1.0 null hsa-miR-29b TargetScan Predicted Conserved microRNA Targets 1.0 0.15008 Glycinergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.537 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042405 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.924708 U266B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.66332 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0629 thorax TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.080459 Oligodendroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.297 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Blindness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.145 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.59689 KYSE450 CCLE Cell Line Gene CNV Profiles -1.0 -1.95631 Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14921 Perturb_8097_KD_SUCLG1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.1936 JM1 CCLE Cell Line Gene Expression Profiles 1.0 1.39076 actin GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8226_KD_EWSR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.2133 MYC-27129775-CHIP-SEQ-CORNEA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null layer 1 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55213 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ7-0011-R6a-SM-2I3G7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09841 Congenital stationary night blindness autosomal dominant 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.25 RERFLCSQ1 DepMap CRISPR Gene Dependency 1.0 2.18939 SNN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34111 ACTR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27473 intellectual disability HPO Gene-Disease Associations 1.0 null Cerebral degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.753 mRNA_RHOX6_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE196671_6_v_8_obox4_mouse RummaGEO Gene Perturbation Signatures 1.0 null EB-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36257 transitional cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.831099 Lysosomal multienzyme complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.672 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.124 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00941 essential GeneRIF Biological Term Annotations 1.0 null NSUN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49516 superficial stratum of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23248 autosomal recessive inheritance HPO Gene-Disease Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46B-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Syncytium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.191 Immunoglobulin-like domain InterPro Predicted Protein Domain Annotations 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.111 PAQR9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50302 Perturb_8238_KD_RBM25_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.31943 GTEX-QDT8-0011-R6A-SM-32PKI GTEx Tissue Sample Gene Expression Profiles 1.0 1.46 Megalencephalic leukoencephalopathy with subcortical cysts 2A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.856 Lobule II Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32618 GTEX-XMD1-0011-R1A-SM-4AT4C GTEx Tissue Sample Gene Expression Profiles 1.0 1.12832 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.43146 Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.063 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.15997 contact site COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.275569 Viscus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 YPEL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95307 ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8261 CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hormone Refractory Prostate Cancer DisGeNET Gene-Disease Associations 1.0 null cerebellar atrophy HPO Gene-Disease Associations 1.0 null mlc1 GeneRIF Biological Term Annotations 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8605 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null reduction GeneRIF Biological Term Annotations 1.0 null Benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.131 stable GeneRIF Biological Term Annotations 1.0 null Bartter disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.247 EFEMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81305 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01906 Megalencephalic leukoencephalopathy with subcortical cysts 2a ClinVar Gene-Phenotype Associations 1.0 null PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30171 GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null either GeneRIF Biological Term Annotations 1.0 null cell periphery COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.406361 Prostate Carcinoma DisGeNET Gene-Disease Associations 1.0 null GSE223008_0_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60911 NES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40166 MTMR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79309 LP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null detailed GeneRIF Biological Term Annotations 1.0 null Glial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.361 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.926143 Escherichia coli infection of the central nervous system_CNS - Brain (MMHCC)_GSE3253 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.46959 volumeregulated GeneRIF Biological Term Annotations 1.0 null Perturb_3821_KO_Zfp280c_SRP330880 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.99057 GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles 1.0 1.27949 SEPTIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69655 autismepilepsy GeneRIF Biological Term Annotations 1.0 null GTEX-P44H-0011-R8A-SM-2XCEL GTEx Tissue Sample Gene Expression Profiles 1.0 0.898661 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-0011-R4A-SM-3GAD3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.30816 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42068 Minor Salivary Gland GTEx Tissue Gene Expression Profiles 2023 1.0 1.28536 Perturb_8188_KD_HNRNPC_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NCIH2110 CCLE Cell Line Gene CNV Profiles -1.0 -1.64028 MYL12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64777 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.23 NAAA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45583 CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.32753 mental deterioration HPO Gene-Disease Associations 1.0 null Plasma membrane bounded cell projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02877 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventriculomegaly HPO Gene-Disease Associations 1.0 null hsa-miR-561 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KATNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04548 Measles DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 Central lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56323 Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE113106_0_v_5_dnm2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-3181 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Perturb_8153_KD_BOP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 exogenous GeneRIF Biological Term Annotations 1.0 null STAT3 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null fibre tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.564434 Peripheral nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.4 GSE184210_0_v_3_glucagon_mouse RummaGEO Drug Perturbation Signatures 1.0 null SP1 ENCODE Transcription Factor Targets 1.0 null Megalencephalic Leukoencephalopathy DisGeNET Gene-Disease Associations 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Culmen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95129 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null lost GeneRIF Biological Term Annotations 1.0 null GTEX-T5JC-0011-R4A-SM-32PLT GTEx Tissue Sample Gene Expression Profiles 1.0 1.18281 CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cerebral peduncle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.664 breast cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306444 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23258 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070164 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.934506 FOXA1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST ChEA Transcription Factor Targets 1.0 null GTEX-XMD1-0011-R6A-SM-4AT5K GTEx Tissue Sample Gene Expression Profiles 1.0 1.20952 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27252 ChIP_REST_18959480 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null dysarthria HPO Gene-Disease Associations 1.0 null H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38184 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37956 Schmidt-Lanterman incisure COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.163 Perturb_8143_KD_NCBP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.5739 496100574_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03318 Perturb_11175_KD_ZNF529_SRP201912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.7609 Anterior commissure TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.809 TIMM50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50593 Piriform area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05208 Renal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.082806 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13324 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_9047_OE_PRRX1A_SRP168742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.37354 HCC78 DepMap CRISPR Gene Dependency 1.0 4.64914 CEBPB_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.74009 ACAD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3749 abnormality of central motor function HPO Gene-Disease Associations 1.0 null GTEX-PWO3-0926-SM-2I5EY GTEx Tissue Sample Gene Expression Profiles 1.0 1.49877 frontal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38338 immunoglobulin GeneRIF Biological Term Annotations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PC3 DepMap CRISPR Gene Dependency 1.0 2.93339 GSE210580_4_v_6_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC3568013-1471-2105-13-128-S5.xls-NME2-Unnamed_1_NME2 Rummagene Transcription Factor Associations 2026 1.0 null familial GeneRIF Biological Term Annotations 1.0 null Lateral habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04 Tail TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.642 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21428 Muscle - Skeletal GTEx Tissue Gene Expression Profiles 2023 1.0 1.88226 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.109 Adrenocortical carcinoma_ACC_TCGA-OR-A5K5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null Demyelinating disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.048 PRAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11753 superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7418 POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE127790_13_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null SP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63992 Lobules IV-V, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95327 Spasticity, Ctcae DisGeNET Gene-Phenotype Associations 1.0 null SARS-CoV MA15_Day7-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.89231 Perturb_8177_KD_RPS3A_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.07679 GSE196117_6_v_0_clarithromycin_human RummaGEO Drug Perturbation Signatures 1.0 null Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08829 GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.967682 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.81445 brain vacuoles MGI Mouse Phenotype Associations 2023 1.0 null Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.336 Internode region of axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.289 Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OGG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41114 GTEX-NPJ8-0011-R7a-SM-2HMJV GTEx Tissue Sample Gene Expression Profiles 1.0 1.15642 Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 Viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.575 Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.18884 NCIH727 DepMap CRISPR Gene Dependency 1.0 5.86725 downregulation GeneRIF Biological Term Annotations 1.0 null progressive neurologic deterioration HPO Gene-Disease Associations 1.0 null Kidney cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.242 HSPA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86257 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXD4L5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53311 brain very small HPO Gene-Disease Associations 1.0 null Perivascular astrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.996 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C1orf74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27437 Retrosplenial area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38815 HNF4A ChEA Transcription Factor Targets 1.0 null GSE120612_4_v_0_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null hek GeneRIF Biological Term Annotations 1.0 null cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.622183 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05582 COLO849 CCLE Cell Line Gene Expression Profiles -1.0 -1.81315 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.935796 Perturb_8220_KD_ZRANB2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.51365 GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02165 PDXK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36826 DNAJC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90933 myotonic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.254183 GSE130081,GSE130082_5_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0026 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.46006 astrocyte GeneRIF Biological Term Annotations 1.0 null GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles 1.0 1.08003 TRIOBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37965 inhibited GeneRIF Biological Term Annotations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE154074_5_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8MK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.646 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null brain ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.162009 PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_upregulated-Genes_upregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3 Rummagene Transcription Factor Associations 2026 1.0 null Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.41019 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null GTEX-WVLH-0011-R2A-SM-3MJFJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.949784 hsa-miR-601 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02439 Perturb_8087_KD_EIF4G2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.6913 Brain cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.014 Autoimmune disease of central nervous system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.045 KMS21BM CCLE Cell Line Gene CNV Profiles 1.0 1.53403 muscular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.123123 CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gestational diabetes DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.428 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.943769 Breast Neoplasms CTD Gene-Disease Associations 1.0 1.05052 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null brain atrophy HPO Gene-Disease Associations 1.0 null GSE119498_0_v_10_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-Q2AG-0011-R10A-SM-2HMLA GTEx Tissue Sample Gene Expression Profiles 1.0 0.959979 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.901264 GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles 1.0 1.05659 NAP1L5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5976 GTEX-RVPU-0011-R1A-SM-2XCAI GTEx Tissue Sample Gene Expression Profiles 1.0 0.9437 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.2858 COQ4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76364 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.33651 ZNF684 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.197 21NT DepMap CRISPR Gene Dependency 1.0 2.04691 ZNF304 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74218 LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59737 cho GeneRIF Biological Term Annotations 1.0 null Perturb_8148_KD_NKRF_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 superficial layers of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05825 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null epidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.34475 PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67017 HOS CCLE Cell Line Gene CNV Profiles 1.0 1.44742 CA SKI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11031 ATOH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47157 TBCEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85879 MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.637427 SCMCRM2 DepMap CRISPR Gene Dependency 1.0 8.60361 intracellular part GO Cellular Component Annotations 2015 1.0 null Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46106 more GeneRIF Biological Term Annotations 1.0 null molecule GeneRIF Biological Term Annotations 1.0 null GSE119978,GSE180930_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Leukodystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.928 biological regulation GO Biological Process Annotations 2015 1.0 null GTEX-XOTO-0011-R7B-SM-4B64R GTEx Tissue Sample Gene Expression Profiles 1.0 0.99155 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVUS-0011-R3A-SM-3GAFD GTEx Tissue Sample Gene Expression Profiles 1.0 1.02757 Perturb_8145_KD_AKAP8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.699 Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50279 NDUFS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37688 breast adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.350001 peripheral portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.88146 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV3-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.942456 Perturb_8105_KD_EIF2S2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.2454 migration GeneRIF Biological Term Annotations 1.0 null ARHGAP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82534 glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.317503 hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.42814 brain cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083461 DCTPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79213 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57467 INA6 DepMap CRISPR Gene Dependency 1.0 4.07148 cell-cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.365095 GSE81803,GSE81912_2_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36579 H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAMAC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26649 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04588 THAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7665 GTEX-QVJO-1426-SM-2S1QY GTEx Tissue Sample Gene Expression Profiles 1.0 1.20542 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43552 KARPAS-422 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50485 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 liver_c HPA Tissue Sample Gene Expression Profiles 1.0 0.905223 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.625319 GSE153836_11_v_2_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null SW403 DepMap CRISPR Gene Dependency 1.0 2.74496 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02008 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.544 amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.95478 AMIGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08253 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.428 astrocyte end-foot GO Cellular Component Annotations 2025 1.0 null H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22098 Lateral loop COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.886 FAM110A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85716 NFIC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-524-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 Secondary motor area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82056 Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Middle temporal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.622 BARX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39229 PMC5110160__F10 PFOCR Pathway Figure Associations 2023 1.0 null Internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.646 Liver TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78299 CAND2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5071 abnormal pyramidal signs HPO Gene-Disease Associations 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null spinal cord TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860468 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.48161 exhibits GeneRIF Biological Term Annotations 1.0 null UGT3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4249 abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.219742 JUND-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MLLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94874 ARPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47449 Perturb_11378_KD_OGT1_SRP311080 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.7834 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.906759 GTEX-WZTO-0011-R6B-SM-4E3J6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00886 Perturb_8237_KD_QKI_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.865313 ZNF841 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87216 SMPDL3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8931 mcf7 GeneRIF Biological Term Annotations 1.0 null spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.6367 AGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20013 specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.171286 Perturb_8172_KD_ILF3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.10591 hsa-miR-4271 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900169 GATA3-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900169 Autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.658 Transitional cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.683 GTEX-XLM4-0011-R10A-SM-4AT5P GTEx Tissue Sample Gene Expression Profiles 1.0 1.16859 urinary bladder cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.890078 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042771 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08041 GSE63048_11_v_8_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Carbohydrate metabolic disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.428 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anchoring junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 OAW42 DepMap CRISPR Gene Dependency 1.0 2.50719 GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null TXNDC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42981 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.57845 failed GeneRIF Biological Term Annotations 1.0 null hsa-miR-3689c TargetScan Predicted Conserved microRNA Targets 1.0 0.072324 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.13935 Megalencephalic leukoencephalopathy with subcortical cysts DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 5.0 CHD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41985 TMSB15A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01922 GIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33838 cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36678 H3K36me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-0011-R1A-SM-2TC6N GTEx Tissue Sample Gene Expression Profiles 1.0 1.15962 abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.480014 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-0011-R3A-SM-2HMJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.839984 Inferior colliculus, external nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16268 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.90978 CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15432_KD_CSN5_SRP316687 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.18799 hsa-miR-4757-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 ING5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94687 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.999422 Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.2425 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.972559 PCDHB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17975 TE6 CCLE Cell Line Gene Expression Profiles -1.0 -1.58212 Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVUS-2826-SM-3GADB GTEx Tissue Sample Gene Expression Profiles 1.0 1.34247 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCCSTCK140 CCLE Cell Line Gene Expression Profiles -1.0 -1.78652 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.665588 Perturb_8360_KD_HNF4a_SRP365071 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.42004 Perturb_8303_KD_SRFBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.133 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.563434 GSE148252_7_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null abnormality of head or neck HPO Gene-Disease Associations 1.0 null Brain disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 5.0 GTEX-UTHO-0011-R6A-SM-3GIJW GTEx Tissue Sample Gene Expression Profiles 1.0 0.988437 posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12115 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900169 Hereditary spastic paraplegia 13 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.284 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer CP in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03521 Uvula (IX) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21213 subcortical GeneRIF Biological Term Annotations 1.0 null GSE213228_4_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE210580_4_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null estradiol_mus musculus_gpl4134_gse23241 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-219-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.059817 Hereditary ataxia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.215 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE153064,GSE153065_1_v_2_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null modulating GeneRIF Biological Term Annotations 1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02256 GSE119978,GSE180930_0_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null REXO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.087 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-506 TargetScan Predicted Conserved microRNA Targets 1.0 0.193083 NEXN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47274 Perturb_8342_KD_NREP_SRP233376 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hemangioma of intra-abdominal structure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.314 suppressor GeneRIF Biological Term Annotations 1.0 null renal cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.741327 superficial stratum of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18138 Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-631 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.175411 Anterior cingulate area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22394 GTEX-X4XX-0011-R4B-SM-46MWL GTEx Tissue Sample Gene Expression Profiles 1.0 0.863485 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63791 cell-cell junction GO Cellular Component Annotations 2023 1.0 null organelle outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.172201 CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.60678 Perturb_8199_KD_CALR_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-X4XX-0011-R5A-SM-46MWN GTEx Tissue Sample Gene Expression Profiles 1.0 1.24006 Perturb_8301_KD_ETF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.974239 cell adhesion GO Biological Process Annotations 2015 1.0 null periventricular stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05512 GTEX-PWO3-0011-R2A-SM-2S1OX GTEx Tissue Sample Gene Expression Profiles 1.0 0.830026 r11 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23114 Perturb_8169_KD_HNRNPA0_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.20248 Perturb_8291_KD_RRP9_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.8112 Hypomyelinating leukodystrophy 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.42 RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null benign GeneRIF Biological Term Annotations 1.0 null GSE126345_0_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.864797 urinary bladder cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.21535 GTEX-QVUS-0011-R4A-SM-3GAE7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19333 NCI-H23 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4646-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Fallopian Tube GTEx Tissue Gene Expression Profiles 2023 1.0 2.62047 clinical modifier HPO Gene-Disease Associations 1.0 null megalencephalic leukoencephalopathy with subcortical cysts 2b, remitting, with or without mental retardation OMIM Gene-Disease Associations 1.0 null Perturb_9816_KD_ARID5B_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.09322 isthmus proper Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10597 CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0549 kidney cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.662784 Perturb_8096_KD_SRSF5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Swim bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.608 GSE212299_2_v_1_abi3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5ST-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Clumsiness DisGeNET Gene-Phenotype Associations 1.0 null embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055864 dorsal nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46593 intermediate stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31828 Eukaryotic translation initiation factor 2B complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.289 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.933369 Perturb_8156_KD_FTO_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 TMEM121B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98126 GTEX-WWYW-0011-R5A-SM-3NB3E GTEx Tissue Sample Gene Expression Profiles 1.0 1.00198 GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7299 Mental Retardation DisGeNET Gene-Disease Associations 1.0 null H3K27me3_CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.73371 Cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 SLC25A44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10241 EVSAT DepMap CRISPR Gene Dependency 1.0 2.57935 hippocampus (hippocampal formation)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1779 Infertility, Female CTD Gene-Disease Associations 1.0 1.17399 PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.894636 expressing GeneRIF Biological Term Annotations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42157 H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DIABLO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2478 Prostate adenocarcinoma_PRAD_TCGA-EJ-7793-01A-31R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P12ICHIKAWA CCLE Cell Line Gene Expression Profiles 1.0 1.66602 Eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.226 hsa-miR-3153 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32735 breast cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.099007 H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21252 GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 0.965431 LPCAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6228 MBD4 ENCODE Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00776 FXYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27057 Perturb_8110_KD_NAA15_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.00153 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 0.855229 JHH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_8101_KD_ATP5F1C_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.73485 cellmatrix GeneRIF Biological Term Annotations 1.0 null Abnormalities, Multiple HuGE Navigator Gene-Phenotype Associations 1.0 null Alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.405 Basolateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06828 Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE179036_1_v_0_trim24_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ependymal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.354 TIMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54604 CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-WL46-0011-R6A-SM-3LK6X GTEx Tissue Sample Gene Expression Profiles 1.0 1.11593 GSE162892_4_v_2_isox_human RummaGEO Drug Perturbation Signatures 1.0 null Posterior limiting nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18906 glycoprotein GeneRIF Biological Term Annotations 1.0 null SULF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89262 primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.90761 immunoglobulinlike GeneRIF Biological Term Annotations 1.0 null NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9037 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.942456 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.43617 Perturb_4263_KO_OTX2_SRP388433 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.80049 Whole Blood GTEx Tissue Gene Expression Profiles 2023 1.0 2.20928 Perturb_8093_KD_PUM1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GALR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00574 Superior colliculus, optic layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18303 nervous GeneRIF Biological Term Annotations 1.0 null SW1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R55E-0011-R4A-SM-2TC5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.27333 496100290_PCx_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.00119 NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40219 GSE148252_7_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.04848 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null proliferation GeneRIF Biological Term Annotations 1.0 null NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.30201 periventricular stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23406 GTEX-WWYW-0011-R1A-SM-3TW8G GTEx Tissue Sample Gene Expression Profiles 1.0 0.838113 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.951851 GTEX-NPJ8-0011-R3a-SM-2HMIW GTEx Tissue Sample Gene Expression Profiles 1.0 1.23002 GTEX-N7MS-0011-R4a-SM-2HMKW GTEx Tissue Sample Gene Expression Profiles 1.0 1.1421 VEGFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47288 PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1 Rummagene Transcription Factor Associations 2026 1.0 null Zona glomerulosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.081 spleen GTEx Tissue Gene Expression Profiles -1.0 -1.70804 GSE238005_0_v_3_c9orf72_human RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Urothelial Carcinoma DisGeNET Gene-Disease Associations 1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-3026-SM-4AT6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.14423 Physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.248 Lymphoid follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.927 HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATAD3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47611 Copula pyramidis, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07115 VDAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9268 clear GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null physiological GeneRIF Biological Term Annotations 1.0 null PMC4470057-12943_2015_398_MOESM7_ESM.xls-probes_KD_inh_in_common-SYMBOL_AR Rummagene Transcription Factor Associations 2026 1.0 null effects GeneRIF Biological Term Annotations 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.877224 FOXA2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LANCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17634 Orbital area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39205 PANC1 CCLE Cell Line Gene Expression Profiles 1.0 1.66779 FADU CCLE Cell Line Gene Expression Profiles -1.0 -1.84181 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8F_Het1A-GATA6_2d_5x_closed-Nearest_Ensembl_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null posterolateral cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91571 a11 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.628 layer 2 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04303 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 frequently GeneRIF Biological Term Annotations 1.0 null CHRNA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86186 CEBPB-20176806-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Lobule II, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40462 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.11749 Glia TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.364 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9048_OE_PRRX1B_SRP168742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.1932 STOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60371 GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.959601 Medial geniculate complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06393 disease GWASdb SNP-Disease Associations 1.0 0.031684 GTEX-T2IS-0011-R6A-SM-32QP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05618 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null raftscaveolae GeneRIF Biological Term Annotations 1.0 null GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.951238 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.89327 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TEAD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14344 Perturb_8173_KD_KHDRBS1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.01722 inhibitory GeneRIF Biological Term Annotations 1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.166095 CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE190186,GSE190188_0_v_10_apoe_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3910 TargetScan Predicted Conserved microRNA Targets 1.0 0.241055 orbital frontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.917056 Prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.064 FLVCR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8669 Secondary progressive multiple sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.487 BEN CCLE Cell Line Gene Expression Profiles -1.0 -1.51069 Immunoglobulin subtype InterPro Predicted Protein Domain Annotations 1.0 null glioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069262 globus pallidus, internal segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57589 CPTP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60589 GTEX-OXRN-0011-R10A-SM-2I5GC GTEx Tissue Sample Gene Expression Profiles 1.0 1.13069 ZNF573 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02291 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.843537 Corpus amylaceum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.797 GSE196962_2_v_6_parg_human RummaGEO Gene Perturbation Signatures -1.0 null SRD5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02544 superficial stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04326 H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.29215 globus pallidus, external segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66494 GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles 1.0 1.00202 doxorubicin_homo sapiens_gpl570_gse46493 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.287235 MFHAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46759 GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.979166 Perturb_5221_KO_Zfp57_SRP173610 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.20022 Perturb_5245_KO_Ssrp1_SRP276644 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.98955 superficial stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13016 GGH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91359 forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE199606_3_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null periventricular stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2951 Genetic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.428 MM370 DepMap CRISPR Gene Dependency 1.0 2.03189 KE37 CCLE Cell Line Gene Expression Profiles 1.0 2.04754 regulation of cell cycle GO Biological Process Annotations 2015 1.0 null EP300_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE173262_6_v_0_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.1897 superficial stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55097 Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04153 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.89038 GSE246195,GSE246305_4_v_5_sin3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null abnormality of coordination HPO Gene-Disease Associations 1.0 null GSE119498_6_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE119498_0_v_5_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Perturb_8249_KD_LIN28B_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.82929 PL18 COSMIC Cell Line Gene CNV Profiles -1.0 -3.24687 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.36768 PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null GSE157049,GSE157051_6_v_4_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Juxtaparanode region of axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.524 Systemic lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.05 hsa-miR-4314 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.09142 microbody LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_8092_KD_PUF60_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-WHSE-0011-R3A-SM-3P5ZM GTEx Tissue Sample Gene Expression Profiles 1.0 1.06577 YY1 ENCODE Transcription Factor Targets 1.0 null CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4787-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE192870_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.306 MEX3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67507 GSE161170,GSE161268_1_v_3_med1_human RummaGEO Gene Perturbation Signatures 1.0 null decrease GeneRIF Biological Term Annotations 1.0 null Purkinje cell layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45904 amygdaloid complex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.837237 Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21428 atrophy/degeneration affecting the cerebrum HPO Gene-Disease Associations 1.0 null Perturb_8094_KD_PUM2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 ARAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68166 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8139_KD_IGF2BP3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.6015 GTEX-WWYW-0011-R6A-SM-3NB3G GTEx Tissue Sample Gene Expression Profiles 1.0 0.98504 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX3-20139965-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Cell projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 GTEX-Q2AG-0011-R2A-SM-2HMIT GTEx Tissue Sample Gene Expression Profiles 1.0 1.23563 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1558 GSE175571_3_v_2_acsl6_mouse RummaGEO Gene Perturbation Signatures 1.0 null IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.906237 PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 rhombomere 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32857 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00057 Bladder urothelial carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.099 posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.834532 FOXA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMD1-0011-R9A-SM-4AT49 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16536 Secondary motor area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05897 GSE87615_1_v_3_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null Myosin XVI complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.508 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null urinary bladder cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.04664 hsa-miR-3689d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Orbital area, medial part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41073 Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Chloride channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.424 HES7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9889 GTEX-Q2AG-0011-R4A-SM-2HMKA GTEx Tissue Sample Gene Expression Profiles 1.0 1.24422 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.68749 extracellular vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.499447 GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13758 Perturb_8131_KD_EIF2S1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.7345 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08688 without GeneRIF Biological Term Annotations 1.0 null Brain edema DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 GSE241701_1_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64049 red nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.863774 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B Rummagene Transcription Factor Associations 2026 1.0 null plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.427497 GTEX-NPJ8-0011-R9a-SM-2YUN5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.831753 Lung adenocarcinoma_LUAD_TCGA-97-A4M7-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Main axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.751 abnormality of nervous system morphology HPO Gene-Disease Associations 1.0 null EN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43891 Retrosplenial area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03477 Primary progressive multiple sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.611 SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35647 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.860004 GTEX-R55E-0011-R6A-SM-2TC5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.28682 pretectal region Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.836078 PTP4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26814 GSE94011_2_v_1_pias3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Dinoflagellate epicone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.951 Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06203 Cervix - Endocervix GTEx Tissue Gene Expression Profiles 2023 1.0 2.25484 Metachromatic leukodystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.275 UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_15191_OE_SOX5_SRP091936 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.3226 Conn's syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.161 cell junction GO Cellular Component Annotations 2015 1.0 null TMTC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07501 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.876628 Perturb_8202_KD_GTF2F1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.07049 Perturb_8241_KD_SRSF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_14746_OE_MEOX2_SRP330486 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.39693 H2AB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58716 Cerebrospinal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.701 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.28035 SNU840 DepMap CRISPR Gene Dependency 1.0 5.59359 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.916437 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8243_KD_SRSF9_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE148066,GSE157787_8_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ependymocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.423818 GSE126345_9_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null UBE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39395 Renal cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.381 intermediate stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12434 cortex of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55146 work GeneRIF Biological Term Annotations 1.0 null PMC5110160__F10 PFOCR Pathway Figure Associations 2024 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null fat_8b HPA Tissue Sample Gene Expression Profiles 1.0 1.02305 Perturb_11406_KD_HNRNPM_SRP143499 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.3958 Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02105 GSE109913_1_v_2_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null HCN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12832 GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 1.0409 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.966769 20460173-ImmPortCD40LandAnti-IgMvsControl GeneSigDB Published Gene Signatures 1.0 null abnormality of higher mental function HPO Gene-Disease Associations 1.0 null FAM43A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37521 mantle zone of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45341 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8264_KD_EEF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.60929 parietal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 ARL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55874 PMC3631253__F4 PFOCR Pathway Figure Associations 2023 1.0 null orbital frontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.16653 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null vrac GeneRIF Biological Term Annotations 1.0 null Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.447 GTEX-N7MT-0011-R3a-SM-2I3GC GTEx Tissue Sample Gene Expression Profiles 1.0 1.42209 Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Corpus callosum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.711 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69273 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.972029 phenotypic abnormality HPO Gene-Disease Associations 1.0 null AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null Inherited metabolic disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.428 fat_e HPA Tissue Sample Gene Expression Profiles 1.0 1.2691 GSE109140_0_v_3_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06018 Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 ATP6V0E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02748 TP53 ChEA Transcription Factor Targets 1.0 null PIGU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48871 HSP90AB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51053 primary auditory cortex (core)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.879692 Immunoglobulin V-set domain InterPro Predicted Protein Domain Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LHX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61447 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.924916 Neuropil TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.243 all HPO Gene-Disease Associations 1.0 null bladder transitional cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.07488 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.055558 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092592 Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.559 Cerebellar nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.787 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ME2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83721 Leukodystrophy DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 5.0 NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.43626 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.113823 critical GeneRIF Biological Term Annotations 1.0 null WBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21654 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.11406 PJVK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61496 basolateral amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09929 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE173810_4_v_6_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NIPSNAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22408 TEAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19585 mRNA_GADD45A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-WZTO-2926-SM-3NM9I GTEx Tissue Sample Gene Expression Profiles 1.0 0.88963 GSE200673,GSE200691_2_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35613 periventricular stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03627 HEPG2 CCLE Cell Line Gene Expression Profiles 1.0 3.4078 Megalencephalic leukoencephalopathy with subcortical cysts DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.643 Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.234 Cerebellar Atrophy DisGeNET Gene-Disease Associations 1.0 null DPPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67047 CBX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55518 Complete Trisomy 21 Syndrome DisGeNET Gene-Disease Associations 1.0 null GTEX-WHSE-0011-R1A-SM-3P5ZK GTEx Tissue Sample Gene Expression Profiles 1.0 0.858835 layer 2 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1001 GTEX-TSE9-0011-R4A-SM-3DB7H GTEx Tissue Sample Gene Expression Profiles 1.0 0.991764 superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60198 dorsolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.63993 GTEX-OXRN-0011-R5A-SM-2I5EF GTEx Tissue Sample Gene Expression Profiles 1.0 1.28918 NCIH82 DepMap CRISPR Gene Dependency 1.0 2.28066 abnormality of nervous system physiology HPO Gene-Disease Associations 1.0 null POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77208 Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.233 motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17635 integral component of membrane GO Cellular Component Annotations 2015 1.0 null core of nucleus accumbens Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.841509 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV4-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-0011-R9A-SM-3MJFP GTEx Tissue Sample Gene Expression Profiles 1.0 1.20162 hsa-miR-3691-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 characterization GeneRIF Biological Term Annotations 1.0 null macroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.919061 Superior colliculus, superficial gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47857 megalencephalic GeneRIF Biological Term Annotations 1.0 null cell projection COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-0011-R5a-SM-2HMK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19395 Gangliosidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.2 GTEX-WWYW-0011-R8A-SM-3NB3S GTEx Tissue Sample Gene Expression Profiles 1.0 0.921915 Perturb_8267_KD_FAM120A_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.15215 internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75142 esrra_19901197_kidney_lof_mouse_gpl1261_gse16623 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.101618 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976079 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3677-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 layer 1 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40677 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null RHBDF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58372 SKNAS CCLE Cell Line Gene CNV Profiles -1.0 -1.35533 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05453 MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.986158 CTCF_WI38_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44758 IGSF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.37193 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11859 single-organism cellular process GO Biological Process Annotations 2015 1.0 null GSE101239_5_v_0_valproic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EOL-1-CELL COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WZTO-0011-R3B-SM-3NMC6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85728 GTEX-N7MS-0011-R8a-SM-2YUMK GTEx Tissue Sample Gene Expression Profiles 1.0 0.98327 Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48263 SNU1076 DepMap CRISPR Gene Dependency 1.0 2.7968 ME1 CCLE Cell Line Gene CNV Profiles 1.0 2.05366 GSE90019,GSE90020_5_v_2_phf8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.093 SCRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25042 Simple lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34383 SH2B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82362 kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.059886 Perturb_11361_KD_METTL3_SRP292229 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.17528 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null astrocytoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.091065 SOX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31087 HEATR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77979 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7504 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886256 Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25815 g0g1 GeneRIF Biological Term Annotations 1.0 null fat_a.V1 HPA Tissue Sample Gene Expression Profiles 1.0 1.19878 H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Idiopathic generalized epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.388 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.968892 Brain Lower Grade Glioma_LGG_TCGA-VM-A8C8-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10690_KD_circPRKAA3_SRP372818 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null LAN2 DepMap CRISPR Gene Dependency 1.0 2.79938 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null localized GeneRIF Biological Term Annotations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.938317 PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.905422 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null TT CCLE Cell Line Gene Expression Profiles -1.0 -2.0984 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.999422 Bladder carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.256 GSE188870,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null BMPR1A_knockout_222_GSE48092 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -0.750829 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.973759 CAPRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06399 BTF3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20399 MTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45037 primary motor cortex (area M1, area 4)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18801 496100448_TCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07162 intermediate stratum of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46472 Perturb_8126_KD_AKAP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-2926-SM-2HMJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14268 Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TE-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inhibition GeneRIF Biological Term Annotations 1.0 null hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11004 Perturb_8125_KD_LARP4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.7696 liver TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.455284 GTEX-NPJ7-0011-R9a-SM-2TC5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.07918 HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.40574 GTEX-OHPN-0011-R9A-SM-4DXUH GTEx Tissue Sample Gene Expression Profiles 1.0 0.856846 Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null