association	dataset	threshold value	standardized value
hsa-miR-1224-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
pentolonium-2305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42971
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66301
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25668
hsa-miR-4704-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K16604405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81106
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.376586
hsa-miR-4682	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05384
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1402
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35866
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44165
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE264010_0_v_1_parp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3519
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96171
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.981254
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09779
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17989
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.822
BRD-K95735693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8447
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64344
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1237	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.822
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.83033
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43214
teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1279
MXI1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32516224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4879
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6849
CS1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4034
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85239
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.95985
testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42649
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16342
OAW-42	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50187
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.4586
BRD-K85912419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23546
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.03179
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	1.59014
ALL-PO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19254
BRD-K45145114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24961
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02411
riluzole-2295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839101
cebpa_22442349_pbmc_lof_human_gpl570_gds4407	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.63632
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69118
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0394
BRD-K83916197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46394
BRD-K65315551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19373
COV318	CCLE Cell Line Gene Expression Profiles	1.0	2.53146
GATA1	ENCODE Transcription Factor Targets	1.0	null
semustine-7492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-K15259298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42156
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.880957
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
P63_DEPLETION_GDS2534_63_human_ME180 cervical carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K36709933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39944
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9031
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42726
BRD-K37165790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67117
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28246
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-K45928581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01728
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Multilymphoid progenitor cell_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
RERFLCAD2	CCLE Cell Line Gene Expression Profiles	1.0	1.40095
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37132
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32956
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908066
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3906
hsa-miR-526b	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K37721603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06629
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9495
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83099
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30944
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.67224
H3K27me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95042
hsa-miR-4720-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51519
BRD-K56915252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10731
POLQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85922
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65944
GSE48812_3_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Testis seminoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09466
UBE2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36891
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03225
Lung squamous cell carcinoma_LUSC_TCGA-22-1012-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
withaferin A-4376	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880763
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68834
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.02647
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16655
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3941	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830786
foliosidine-4295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alpha-estradiol-6169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K14589361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07872
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
T3M4	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.881473
BRD-K90902537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03404
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04684
BRD-K77601667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20107
Kidney Chromophobe_KICH_TCGA-KL-8342-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09777330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67369
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61985
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15621
KMS11	CCLE Cell Line Gene Expression Profiles	1.0	1.57499
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27502
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071577
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05084
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.83789
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.61373
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19251
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20501114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10352
BRD-K00976973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48381
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93299
BRD-K50008138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05993
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1164
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1895
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45289917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50657
hsa-miR-4773	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K09378334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09506
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0693
hsa-miR-4474-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K01667746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68547
ZR75_1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.871003
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80333
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86603
USP6NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14598
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908066
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176328
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5953
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60608
ACC3	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.15783
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6733
BV-173	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
Teratocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.34604
BRD-K75707803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00452
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19553
Bladder Urothelial Carcinoma_BLCA_TCGA-LC-A66R-01A-41R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57883
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
taste	GAD Gene-Disease Associations	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05178
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.16477
Perturb_4882_OE_BCL2L1_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.76077
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917474
SNU61	CCLE Cell Line Gene CNV Profiles	1.0	2.47565
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.51034
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068004
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90535
hsa-miR-4303	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7698
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14215
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21016
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94543
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28096758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37202
Ankylosing Spondylitides_macrophage_GSE11886	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.39178
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_4897_KD_U2AF1_SRP160510	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.8568
teratocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533856
BRD-K75807319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06865
BRD-K75637705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53138
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.25858
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14893
BRD-K01749472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16902
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.31206
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45806
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00298
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE210476_11_v_3_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.91639
celecoxib-206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-557	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K46824282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31875
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27757
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34636
em3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
BRD-K48436333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18035
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6945-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77950699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83316
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57464717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35017
BRD-K69611470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22513
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08842
BL3434 (CRTC1)	NURSA Protein Complexes	1.0	null
PMC12494973-41467_2025_63880_MOESM1_ESM.pdf-176-RUNX2_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93942001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06246
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MU-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.94419
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913574
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LRATD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74053
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07918
BRD-K37402529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13466
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933179
BRD-K61383885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04635
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47237224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34164
BRD-K32403186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8499
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040861
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09682
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52237
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933179
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00353
HCMV_TB40E_24Hour_19951172_GSE14816	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.00577
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.43146
saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.44404
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25985
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41192068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07138
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.18705
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63453
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15436
hsa-miR-3164	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51139
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.913815
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.96257
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.24922
PPP3CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09926
BRD-K09149805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14859
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11425
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2128
OVCAR-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K59744424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02982
Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.259
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21775
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	0.864758
BRD-K86077185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31813
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6597
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0436
LOUCY	GDSC Cell Line Gene Expression Profiles	1.0	1.47743
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-K28814368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86065
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38446
BRD-K99546030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2715
Perturb_17223_KD_NANOG_ERP128142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ciclosporin-602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
MC-IXC	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28248
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2826
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RXF393	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.934411
Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	-1.0	-2.45319
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3667
BRD-K72467884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70339
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55314
mepenzolate bromide-2169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A3-KAW	GDSC Cell Line Gene Expression Profiles	1.0	1.58449
BRD-K99660943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10205
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27318
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09142
BRD-K97377031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12074
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31584
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06408
BRD-K82126187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20733
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0552
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTDK-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01075
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-2102Ep-Genes_deregulated_in_2102Ep_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
chr8_132110254_C_T_b38	GTEx eQTL 2025	1.0	1.32199
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0727
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.72292
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47761
troglitazone-504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84601599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25274
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.38616
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.15341
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43037
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.246124
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65463
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2413
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8
Kidney Chromophobe_KICH_TCGA-KO-8416-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
other	GAD High Level Gene-Disease Associations	1.0	0.293278
496100544_PCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59453
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15993
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.8684
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4528
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01519
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24769
oligohydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.2909
pipenzolate bromide-4484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RELCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04802
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.55948
egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.676172
timolol-5645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39594
hsa-miR-412	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
chlorcyclizine-6053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3612
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73665
Charcot-Marie-Tooth disease type 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00329
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10691
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.65955
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77447
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06811
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.72292
BRD-K31348453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0891
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06346
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4861
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2022
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95312
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A57762296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79969
Perturb_8660_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.5926
PL18	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45215
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7769
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44664
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903553
Brain Lower Grade Glioma_LGG_TCGA-FG-7641-01B-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.37408
SK-N-DZ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43955991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03127
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.84993
BRD-K02420839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68473
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2349
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38022
BRD-K76960970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02171
BRD-K28698418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7562
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9324
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0387
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.82135
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6994-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12194
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6748
ERG	ChEA Transcription Factor Targets	1.0	null
BRD-K03562091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4661
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
extracellular region	GO Cellular Component Annotations 2015	1.0	null
Endometriosis_Endometrium_GSE7305	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.34765
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0261
SKNFI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72662
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00334
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.89575
LCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10361
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36979
nordihydroguaiaretic acid-203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51735
Perturb_8665_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.60362
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952263
BRD-K32043305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0336
heptaminol-6015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1804
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08136
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23454
cyproterone-6124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12984
OTUD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3372
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE95771_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50033
GSE211866_2_v_1_usp11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
methylbenzethonium chloride-3943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A67254212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4104
BRD-K06997715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27245
INTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73994
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040554
genistein-4459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SAOS-2	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14234
BRD-A91404865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55683
Taste	dbGAP Gene-Trait Associations	1.0	0.50886
Perturb_4883_KO_NOXA_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.19261
BRD-K62982188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45599
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845344
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042673
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057543
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
amprolium-1479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8539
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37948
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13195
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K46306993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08076
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889363
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8469
Inclusion Body Myositides_Muscle tissue_GSE3112	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.4603
CAOV4	CCLE Cell Line Gene Expression Profiles	1.0	1.90329
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933179
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2053
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8932
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.76765
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069081
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50685439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41183
Adipocyte	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.17133
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K13782363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4339
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WJ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42674
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96263
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K60828476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54591
BRD-K26667087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04219
hsa-miR-205	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.986294
NCI-H3122	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9068
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4379
Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01472
hsa-miR-4690-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K25081034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28133
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6475
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.89892
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844294
CRCGN015_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0967
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K61973443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13023
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LU-65	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACADSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01566
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956563
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.67675
BRD-K13204142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58531
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4877
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40359
BRD-K30198800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30718
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68852
Brain Lower Grade Glioma_LGG_TCGA-HW-7487-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25236390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38625
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7968
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.80842
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K60170940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29313
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2221
Choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1289
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.075
BRD-K09720842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17628
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.49666
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53942
BRD-K45609222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00524
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9939
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plastid envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.99507
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23578
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.880828
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81S-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21759
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4257	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
TGBC1TKB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74706
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47982
felbinac-3398	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KIJK	CCLE Cell Line Gene Expression Profiles	1.0	1.4414
BRD-K54100265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09543
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87258
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
tetroquinone-4078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
METTL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32531
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.04261
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rad51B-Rad51C-Rad51D-XRCC2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.989
BRD-K45936761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94641
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9207509-DataSheet_1.docx-3-FOXK1_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06286
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3179
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
WSUDLCL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92254
CP-319743-7491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K72646819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6241
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02133
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063901
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14388
BRD-K42271016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47242
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K44427106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02831
NUAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06812
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090574
vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.25297
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01696
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539
BRD-K82827604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10475
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7111
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45492
Perturb_4899_KD_TP53_SRP067400	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5459
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94624
BRD-K06218527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1877
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryo	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Mis6-Sim4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5059
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K33268483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30752
nifedipine-603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859579
IST-SL2	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-K21671578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37536
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894685
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.34019
supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268137
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Granular cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1654
Germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63401
P53-22127205-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
testicular cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.527928
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00572
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1781	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31746
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
OPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5644
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.991309
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.24485
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975176
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.02743
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K75135426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10422
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830786
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36498
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4653-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18345677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22405
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.702
BRD-K11726285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42287
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46326
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9102
SKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01613
hsa-miR-4701-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986436
GAK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Charcot-Marie-Tooth disease type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19488
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09576
hsa-miR-4757-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T2-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT29	CCLE Cell Line Gene CNV Profiles	1.0	1.89304
BRD-K83801418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0098
Perturb_8778_KI_SMARCB1_SRP223162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.6969
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1988
hsa-miR-513a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1508
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
HCC38	CCLE Cell Line Gene Expression Profiles	1.0	2.00189
hsa-miR-509-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Reading disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
potter's syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.19244
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-889	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2465
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4349
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.225
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.64521
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52939
PKIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54179
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77644
BRD-K89447773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51359
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75E-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52706
hsa-miR-4751	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K31608682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02612
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060283
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46497
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.073
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08198
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217554
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89482
Schwann cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
BRD-K28535931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70404
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82194980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03435
Teratocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871167
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0283
oxybuprocaine-3996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.27055
BRD-K57271749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48808
BRD-K57756744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23647
BRD-K26586614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39312
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31615
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
trimethadione-2846	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K32475622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28693
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.09258
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8424
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44219
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K0-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
wehi164	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00257
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31734
BRD-K07768565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.029
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41983
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73573019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50251
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.04261
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71108
BRD-K03344897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12091
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A11130173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32011
peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.30838
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68035
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69775
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3717
hsa-miR-3122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09337
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.0486
7-aminocephalosporanic acid-3258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908066
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
HAUS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18591
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29977
ES6	GDSC Cell Line Gene Expression Profiles	1.0	1.46749
BRD-K26195700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15172
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546533
BRD-K00231307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44077
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2976
496100501_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12443
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28357
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5472759-ncomms15770-s2.xlsx-KIRC_mean_chr8_GISTIC_CN_by_gen-Supplementary_Data_1_TCGA_KIRC_mean_CN_near_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3167
HD-MY-Z	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TK-01A-42R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854637
celecoxib_homo sapiens_gpl8300_gds3384	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01207
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3266
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03279
BRD-K77241556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20585
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01762
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18876
GSE205163,GSE205164_3_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE128730_4_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100291_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09247
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79624
BRD-K01643633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25265
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.76655
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16263
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03169
BRD-K01077691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13442
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60948317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23455
Perturb_8898_KD_IGF2BP1_SRP359044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.4508
BRD-K03305572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73123
15(S)-15-methylprostaglandin E2-7494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55732
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072707
GSE233112_2_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUN-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8846
hsa-miR-4436a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K82909038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10506
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4743
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83609
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94358
CAL120	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4942
H4	GDSC Cell Line Gene Expression Profiles	1.0	1.49703
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00823
Papillary transitional carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6186
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90295
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.61246
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1355	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49352
BRD-K71184289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03843
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33679
BRD-K79734831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02957
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51511
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08292
SNAI1_OE_GDS4596_344_human_SW480 - Colorectal cancer cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K69074358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33937
haloperidol-4427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K34482448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07471
Perturb_8667_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07566
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
esculetin-3120	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MG-63	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3140-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K96485138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70925
TP63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51377
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4937
BRD-K52017042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05624
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77177
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.09154
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0969
MAFK	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849247
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3913-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040785
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216528
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43365
Perturb_8666_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K08806664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5829
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20363
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961479
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30973
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
parbendazole-3799	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.565
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.822
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CW-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3179	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2723
MFE-296	GDSC Cell Line Gene Expression Profiles	-1.0	-2.09656
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25517
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3208
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.987162
benperidol-4781	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16988512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05264
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6515
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32872
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63782
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.688
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.70346
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40357
CRCGN009_HEPG2_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10831
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7281
Perturb_4878_OE_BCL2L1_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76948
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.123
IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97534
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3447
PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40602242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1717
karakoline-6059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DCA_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1289
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.516
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25611
BRD-K51398207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19142
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.27167
BRD-K93567937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86806
BRD-K02299361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28103
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16425
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21508
496100303_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44395
diclofenamide-3366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94403
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07246
hsa-miR-3921	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-2.42766
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65895
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16849
BRD-K69171646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20994
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7145-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35032
BRD-K89935890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4134
BRD-K55665639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11769
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59519
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
LM-1685-207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
butyl hydroxybenzoate-5245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K84688359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54823
indometacin-503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K19969409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1173
em2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44968
BRD-K75620843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04508
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09655230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8455
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18683
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849279
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
metformin-4	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68937579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69913
BRD-K23666684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21944
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-M08461891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79781
inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.718846
BRD-K85720719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25458
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-519c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17547
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4152
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33748896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87485
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11365
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8049
BRD-K90138084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49866
Perturb_17217_KD_NANOG_ERP128142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NUMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16933
nalbuphine-2225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
metformin-3	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Rett Syndrome_frontal cortex_GSE6955	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.580167
MAX	ENCODE Transcription Factor Targets	1.0	null
Inner kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
rofecoxib-205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K78747341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61889
ricinine-5725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04603
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1119
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22879
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44797874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67152
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K81888673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1757
CRCGN015_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29223
POLR1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31844
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2015
N-acetyl-L-leucine-3085	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K72216066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16717
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.78522
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055594
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-NTera-2-Genes_deregulated_in_NTera-2_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
LXF289	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46976
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04537
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14281
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85912
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	2.03232
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45525014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48223
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4651
hsa-miR-507	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71406
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71483
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44431
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00849
JJN-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43143
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41722
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XK-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48589
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0295
SKM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.0524
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1197	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K85572169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33077
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881026
BRD-K07396550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3617
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88505
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9983
SC-58125-208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51031
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3223
Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-556-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32171
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.46675
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H1-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69152679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49019
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62733
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACHN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.570329
estradiol-4465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MKN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79997
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12793
BCB000040-7493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4732
haloperidol-5200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prestwick-674-4276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.771252
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52788
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07569
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
TRABD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60873
BRD-K00562490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90805
hsa-miR-331-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
A2780	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41982
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292436
hsa-miR-4298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27638
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04624
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058438
GSE185744,GSE185747_2_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29760532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19985
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1653
PC3	CCLE Cell Line Gene Expression Profiles	1.0	1.77337
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00871
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03486
PMC8185471-mmc7.xlsx-DEGs-SOX15_peaks-Unnamed_2_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
SKM1	CCLE Cell Line Gene CNV Profiles	1.0	1.43042
spironolactone-2226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-61	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K40838215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44517
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15375
erythromycin-6729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00673
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89223
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33176
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.4186
NCI-H1781	COSMIC Cell Line Gene Mutation Profiles	1.0	null
testicular cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08891
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9141
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053521
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95231
epiphysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844126
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1111
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09281
USF1	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9633
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46175
Rad51C-XRCC3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926538
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47505
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85902
fulvestrant-7495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1975	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879608
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46836
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48032
BRD-K41326905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92583
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06361
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
RAD21	ChEA Transcription Factor Targets	1.0	null
sirolimus-6180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66532
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04649
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83753
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
etamsylate-2915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09284
Neoplasm, Residual	DisGeNET Gene-Phenotype Associations	1.0	null
GSE182680,GSE182683_5_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1025
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.706351
valproic acid-433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-520c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CIAPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00344
tanespimycin-4449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23705
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21621
Dyslexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_8481_KD_DAP5_SRP073613	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.6383
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62948
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX1_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3218
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder urothelial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33822
BRD-K08300592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25199
hsa-miR-592	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95846
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286381
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889363
Perturb_4891_KO_NOXA_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.94595
BRD-K33961995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06132
BRD-K69840402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05811
BRD-K52582315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36518
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.57883
BRD-K91297952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66673
Plastid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.169
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0289
BRD-K31575995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41552
SKLMS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63176
CAKI1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.957128
kinetin-4477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029508
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39679
proteasome regulatory particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18516
SW626	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1623
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17022
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68948
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2824
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49464
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69354
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.899881
VPS72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0063
BRD-A71933035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47624
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11345
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36087
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33436
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	-1.0	-2.32016
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7648
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04465
BRD-K38211037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06121
GSE190534,GSE190536_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KRAS.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26031
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847247
flumetasone-3610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
15902281-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
Sarcoma_SARC_TCGA-FX-A3TO-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5595
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.88043
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36054
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7943
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16193
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6522
BRD-K93283197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14446
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842874
CACTIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09901
Brain Lower Grade Glioma_LGG_TCGA-DU-6408-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14487
Ca-Ski	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52536
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_1_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59769
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31608
KP4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48953
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5863
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
HS-578-T	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9049
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85239
L-363	GDSC Cell Line Gene Expression Profiles	1.0	1.73454
benign paroxysmal positional nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.93139
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Prestwick-665-3681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09466
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.63845
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49079
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42055
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46836
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93705
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35905
BRD-K03331449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04123
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6834
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157S_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01848
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.851246
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50434315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37718
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21660570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79385
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49496
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0294
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.40364
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20997
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29102
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054416
GSE121198,GSE129779_0_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32418104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38081
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840063
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Adult T-cell lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
Perturb_8661_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.9059
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39403
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4502	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41146
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73472
hsa-miR-661	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Perturb_9063_KD_NANOG_SRP100928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.78693
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.02144
CUX1-19635798-MULTIPLE-CANCER-TYPES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12569
isotretinoin_homo sapiens_gpl8300_gds3215	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2502
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0707
KASUMI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.05833
BRD-K48665080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06666
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
santonin-4353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AURKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02634
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8163
A172	BioGPS Cell Line Gene Expression Profiles	1.0	0.908378
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0612
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18675
496100447_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07398
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01232
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.205254
TE8	CCLE Cell Line Gene CNV Profiles	1.0	3.11331
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10822
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.934
BRD-K86002795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83255
Adrenocortical carcinoma_ACC_TCGA-OR-A5K6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A78982410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00084
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65675
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34883
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	1.1894
berberine-6791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.41229
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3833
BRD-K96779993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66334
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157S_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HD-01B-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC265	CCLE Cell Line Gene Expression Profiles	1.0	1.56365
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2953
ethosuximide-2280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4316	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37459038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34238
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30966
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.38778
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21935128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29682
BRD-K35122752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39643
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51888
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	2.42895
hsa-miR-4724-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE95771_0_v_2_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.85975
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K59519347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54479
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5658
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	2.27828
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24369860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08769
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE48812_2_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKMEL2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47371
BRD-K19712167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46939
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9555
metoclopramide-4285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K90882192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04405
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35560933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31494
DEF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0364
ANGPTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2357
BRD-K87146261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53801
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865567
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CK-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48746
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10465
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-635	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Perturb_8663_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.3524
BRD-K24965236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35862
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K19516614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08324
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2081	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K17602350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03824
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.21425
WWC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64981
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00334
BRD-K91079447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03613
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17395
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7864-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM14	ChEA Transcription Factor Targets	1.0	null
BRD-K61441533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17842
BRD-K68073004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17069
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-224	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine lavage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89045
BRD-K89767945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27328
2313287	CCLE Cell Line Gene CNV Profiles	1.0	1.38225
ITPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32092
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54287
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51393
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01789
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF2LX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15053
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94675
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13083
hsa-miR-4757-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88936
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1339
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2626
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3912
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0544
Perturb_8664_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046905
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73604422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14227
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37518
HSF1_KD_GDS1733_754_human_HeLa cells -  0 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78937
DOK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96344
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5251
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862654
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.16531
BRD-K36031198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45784
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42465
hsa-miR-3188	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
EW-1	GDSC Cell Line Gene Expression Profiles	1.0	1.73279
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1615
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07696
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lymecycline-5994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Common traits (Other)	GWAS Catalog SNP-Phenotype Associations	1.0	0.22914
BC-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042541
BRD-K81779733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35093
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prestwick-664-3613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.11238
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18467
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02588
GSE225869_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Retinitis pigmentosa 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3196
BRD-K05902089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11119
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1997
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26638
Amyotrophic lateral sclerosis type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907254
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84729
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.951245
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917872
Ca9-22	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62371
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61812
BRD-K07368164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52815
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K89260735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50595
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2203
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37132
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60508
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IG-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metformin-1	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
IM-9	GDSC Cell Line Gene Expression Profiles	1.0	1.6513
BRD-K85546819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02916
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J7-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226770_3_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55298
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.040961
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYNCRIP_OE_GDS4596_85_human_SW480	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CUX1	ChEA Transcription Factor Targets	1.0	null
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5018
celecoxib_homo sapiens_gpl8300_gse11237	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2889
hsa-miR-1302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Testicular cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.973
Teratocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.985
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65545
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.71659
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98975
sirolimus-6167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K35308744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01886
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9494
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00734
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
DDX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4417
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.33434
SKM-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
hsa-miR-4768-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835117
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.971613
BRD-K95591629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17225
GSE128730_7_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03581
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.45413
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81W-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933179
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99225
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06593
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01602
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45204
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3211
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32443
Familial combined hyperlipidaemia_Blood monocyte_GSE11393	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.61509
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912922
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.36795
EWSR1_KD_GDS4962_467_human_not specified	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03756
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MCF10A_KD-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824743
BRD-K10433727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39711
MKN28	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059838
IZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22858
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6827
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.29044
Perturb_8900_KD_SRF_SRP359044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.4035
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K39979888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18941
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04874
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33505770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31078
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09896
Lung adenocarcinoma_LUAD_TCGA-55-8089-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1304
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50678
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38628
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865567
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2326
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
Perturb_4885_KD_TP53_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.42057
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47852
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1572
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17696
BRD-K12328371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18544
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PIAS1_KD_GSE44024_133_human_breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05434
BRD-K73834056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44678
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A0TN-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48255
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.33455
PIAS1_Depletion_GDS5076_12_human_MDA-MB 231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.49691
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00257
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
SDHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0469
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6954-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TWIST1_01_252	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58635
Bipolar Disorder_frontal cortex_GSE5389	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.60886
BFTC-905	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
NCI-SNU-1	GDSC Cell Line Gene Expression Profiles	1.0	1.69437
betamethasone-dipropionate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40019
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	2.25962
HD-MY-Z	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	2.2117
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84957
EWSR1_KD_GDS4962_468_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38822
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-Commonly_Deregulated_Genes-Genes_deregulated_in_both_2102Ep_and_NTera-2_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121198,GSE129779_0_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-518d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950238
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17326
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2012
dms79	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89161
BRD-K81976047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50676
Choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898075
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947935
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3967
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8415-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6297
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41722
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-526a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.99427
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912922
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63414
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K75281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03583
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02844551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0174
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46126513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10591
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7504
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01344
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992796
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.987118
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1629
Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17220_KD_NANOG_ERP128142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LY-294002-501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
5707885-6390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17395
bendroflumethiazide-3758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53703060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21686
496100553_TCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26455
Brain Lower Grade Glioma_LGG_TCGA-WY-A85B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13211285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31745
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3028
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260945
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43019
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51214
BRD-A13983189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08429
BRD-K72933250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00569
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	1.04261
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1765
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14215
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.171289
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.24425
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.83439
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94403
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04851
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64699
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11101
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25474
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.843461
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88104
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07276
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1323
BRD-K35562235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42158
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0088
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7304
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.3142
BRD-K40060703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14026
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040723
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
19061838-TableS15	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.46483
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929342
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84699
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44009
valproic acid-4433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64L-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11679
BRD-K70093308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29172
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16487
U251MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50105
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.65207
PHA-00745360-3824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	1.05066
BRD-K36847650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00177
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50789
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0039
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291008
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05271
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
LYRM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03131
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0417
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	2.26883
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81F-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proteasome accessory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.182723
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
BRD-K24929039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.314
Lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H23	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
CRCGN015_MCF10A.TP53.M_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92975
BRD-K43674766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60023
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5326
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7495
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.326
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.5313
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17026
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3519
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35283
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	3.05387
mRNA_FOXP1_21924763	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TIMM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28717
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868475
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07081
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0908
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.977002
Sarcoma_SARC_TCGA-DX-A1L4-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3157-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.23516
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.996398
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77426
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.40521
BRD-K57786075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00358
BRD-K68149575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20495
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.4598
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1307
KP-4	GDSC Cell Line Gene Expression Profiles	-1.0	-2.88317
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21599
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25771
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19171
hsa-miR-4704-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BV173	CCLE Cell Line Gene CNV Profiles	1.0	1.5599
BRD-K85649685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03584
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71315
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76847
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MK-886-601	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K83185986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1466
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24342
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89154
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03519778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31506
Perturb_4889_OE_BCL2L1_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.39092
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.12937
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.97077
BRD-K58286708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83677
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8339
BRD-K82107155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24703
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.940274
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933179
BRD-K89278382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08809
egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.272997
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22371
KRAS.AMP.LUNG_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
DACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06047
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95577144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28988
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19791
PATU8988S	CCLE Cell Line Gene Expression Profiles	1.0	1.50734
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.00918
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	2.84546
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.083
brain	GTEx Tissue Gene Expression Profiles	1.0	1.20452
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
BRD-K40189164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32111
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0764
SNU308	CCLE Cell Line Gene Expression Profiles	1.0	1.46311
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03225
BFTC905	CCLE Cell Line Gene CNV Profiles	1.0	1.44582
KMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.80842
estradiol-6200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96355
hsa-miR-4799-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55372
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23372
JAK2_knockout_79_GSE26188	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.52573
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4039
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.37738
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48301
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.061
SW1573	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62801
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01282
BRD-K58996625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21333
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44032
clenbuterol-5631	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4913
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915726
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825997
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67729
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72188
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06881
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6281
BRD-K48260102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49427
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08963
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841503
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62015
Lung adenocarcinoma_LUAD_TCGA-62-A46S-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Doyne honeycomb retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Mrsv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50936
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12967
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2312
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73606
Brain Lower Grade Glioma_LGG_TCGA-FG-8188-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04021
BRD-K37696710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37658
PMC10960568-mjad044_supplemental_file.pdf-38-HES1_HES1	Rummagene Transcription Factor Associations 2026	1.0	null
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84097
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO783	CCLE Cell Line Gene Expression Profiles	-1.0	-3.08644
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41768
BRD-K86711517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33693
BRD-K69453385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30329
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906654
Fanconi anemia complementation group G	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GS-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEG-01	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
arachidonic acid-604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	1.33577
BRD-K80073743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23226
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15767
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9161
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC827	CCLE Cell Line Gene CNV Profiles	1.0	1.98025
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alpha-ergocryptine-3817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84096
GSE62292,GSE62295_2_v_1_col4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_3h_vs_Control-Unnamed_1_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
UHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48665
BRD-K75984692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48147
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Leber congenital amaurosis 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66248685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17834
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K34942615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05712
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17395
ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BZ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
hsa-miR-3162-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040626
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AdrenalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.23269
STAT1_KD_GDS4754_159_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4323	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18654
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5302
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_17648_KO_CEP83_SRP379856	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.02984
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75575
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.61412
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
labyrinthine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.11267
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64432
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.58
rectum	HPA Tissue Protein Expression Profiles	1.0	1.04261
BRD-K61315077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28746
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1515
PANC-08-13	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-K89515752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21129
Teratocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71115
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4983
hsa-miR-4264	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00988
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.77365
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30149
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07207
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22351
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0683
SIMA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57899
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31107
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25V-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-619	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96552
BRD-K49203165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20483
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22793
BRD-K12886565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22912
BRD-K93956318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05124
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01195
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38397
BRD-A04975445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23666
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48860650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05787
BRD-K33122655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01757
NCI-H211	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81961
teratocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52556
hsa-miR-4691-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IE-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.69
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.8198
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5573-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86769
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8345
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883977
BRD-K51972131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00876
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00675
BRD-K50713036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47735
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32592
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09137343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33677
BRD-K01030150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41803
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38118
BRD-K24711162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21302
HCC-44	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43993
GSE147626_2_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Testicular cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89343
CAL-39	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
hsa-miR-4452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973493
CRCGN017_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05115
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F7_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44652
BRD-K07164317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42757
KIF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81623
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9853
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5082
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19127
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06256
NCIH2081	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44644
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1277
GSE225869_1_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15654812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20884
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
rent1_15448691_hela_lof_human_gpl8300_gds705	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.442592
BRD-K18101567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20818
inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.37225
TUBGCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39693
Embryonic germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1288
BRD-K05584347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40343
BRD-K01973494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76678
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75866
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9117
BRD-K88478877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08986
hsa-miR-519b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PF382	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57499
Testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.707
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.72391
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900092
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Daudi	GDSC Cell Line Gene Expression Profiles	1.0	2.59883
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17325
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5664
KNSTRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87021
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06435
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848496
CBC32 (POLDIP3)	NURSA Protein Complexes	1.0	null
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.360026
LNZ308	CCLE Cell Line Gene Expression Profiles	1.0	1.35496
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K75539052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29116
BRD-K90797575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75138
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898965
etanidazole-5730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74873856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28495
BRD-K12115687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00465
PRECLH	CCLE Cell Line Gene Expression Profiles	1.0	1.59537
BRD-K10182289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20785
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64262
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08715020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57526
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.798
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12194
BRD-K79807180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63066
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9655
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.95975
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0852
GSE186112_1_v_0_med23_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46315
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38168
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K93927229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14743
hsa-miR-603	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16342
BRD-K25844701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5938
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25877
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_6_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52049165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69106
COLO-205	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52991
BRD-K07589203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19437
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_39_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	1.0	0.847924
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5273
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58088
HCC2935	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75547
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8706
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.53766
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8534
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95248
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE238018_1_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5745
BRD-K93894185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59044
496100598_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.22878
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	1.33075
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3144-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28089
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79626
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104126
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050769
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZC4H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56861
TE-8	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
HCC1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.21258
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1975
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95981
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8289
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865567
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1289
Brain Lower Grade Glioma_LGG_TCGA-DU-6403-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SK-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null