association	dataset	threshold value	standardized value
IgG immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.945
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960683
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SUDHL6	CCLE Cell Line Gene Expression Profiles	1.0	1.35595
Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
Sarcoma_SARC_TCGA-DX-A8BQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
peptide antigen assembly with MHC protein complex	GO Biological Process Annotations 2025	1.0	null
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52095
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormality of the ulna	GWASdb SNP-Phenotype Associations	1.0	1.72225
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73608149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08384
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11554
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24554
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65423
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
BRD-K64748422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68342
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Shellfish allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16359
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.155
BRD-K24815102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31725
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17356
ASTRA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.045
positive regulation of immune response	GO Biological Process Annotations 2015	1.0	null
Lymph node disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.676
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Phosphorylation of CD3 and TCR zeta chains	Reactome Pathways 2024	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8631
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.718
Triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.85229
Integral component of lumenal side of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the upper limb	GWASdb SNP-Phenotype Associations	1.0	1.58847
BRD-K45893504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40886
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal response/metabolism to endogenous compounds	MGI Mouse Phenotype Associations 2023	1.0	null
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062071
OMC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.63314
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
pheneticillin-5763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTSS	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Buccal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
clathrin-coated endocytic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
abnormal axial skeleton morphology	GWASdb SNP-Phenotype Associations	1.0	1.04359
abnormal cortical bone morphology	GWASdb SNP-Phenotype Associations	1.0	1.72225
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
METTL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.162
positive regulation of cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00721
Allergic disease (asthma, hay fever or eczema)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.13979
lymph node disease	GWASdb SNP-Disease Associations	1.0	0.794247
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56312
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38831170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15541
patchy osteosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846202
vacuolar membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hladqb2	GeneRIF Biological Term Annotations	1.0	null
TYKNU	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.74299
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.68476
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
BFSP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610473
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05876
MHC class II, beta chain, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41066
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05468
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4717
MST cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217762
PRKCQ	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8127234-12885_2021_8319_MOESM2_ESM.docx-0-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
epitopes	GeneRIF Biological Term Annotations	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67682
Complement C3 and C4 levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.15229
Upper respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.045
terbutaline-5764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sensorineural hearing loss	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.853201
BRD-K50129495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55472
Squamous cell carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160658
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
hsa-miR-4522	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.913
BRD-K00551139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15964
WM2664	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62654
BRD-K93516545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9055
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary biliary cirrhosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4699
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2035
S100A8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.487
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.446
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34739
Cutaneous malignant melanoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
trans-golgi network membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.88819
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
HOM-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.948
Hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.869
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30133
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.190786
Dental plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1131
BRD-K30172718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08481
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.093
MHC class I protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.491
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
demyelinating disease	GWASdb SNP-Disease Associations	1.0	1.80801
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
TRAF3IP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569229
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
positive regulation of lymphocyte activation	GO Biological Process Annotations 2015	1.0	null
endosome membrane	GO Cellular Component Annotations 2025	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.319
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33106
Disabling Disease	DisGeNET Gene-Disease Associations	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1731
ACTR1A	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dr0401	GeneRIF Biological Term Annotations	1.0	null
Tomato allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4882
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	0.861774
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07476
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54262203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66689
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNASE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47218
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66288
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15913
increased bone mineral density	GWASdb SNP-Phenotype Associations	1.0	1.72225
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of immune response	GO Biological Process Annotations 2025	1.0	null
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24898
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.43338
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1137
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
interleukin-2 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
lysosomal membrane	GO Cellular Component Annotations 2015	1.0	null
sirolimus-5975	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850133
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
EN	DepMap CRISPR Gene Dependency	1.0	3.71585
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.715
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43391
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9444
DOV13	CCLE Cell Line Gene CNV Profiles	-1.0	-2.53734
BRD-K09521953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05464
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13757
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35562
susceptible	GeneRIF Biological Term Annotations	1.0	null
Interferon regulatory factor 7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.857
OTC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00634817
hla	GeneRIF Biological Term Annotations	1.0	null
BRD-K47673408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67687
disease	GWASdb SNP-Disease Associations	1.0	0.280146
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
MDA-MB-453	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46372
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.691
BRD-K82105033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03253
BRD-K14476597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22943
antigen processing and presentation of exogenous antigen	GO Biological Process Annotations 2015	1.0	null
Strep throat	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891253
CCL23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541346
abnormal artery development	MGI Mouse Phenotype Associations 2023	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8786
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17874
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57397
Thymic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
NCIH1930	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0739
CTSH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
SUMO activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.324
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.269
Lung function (FEV1)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00458
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0701
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06087
type i diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	3.07973
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K18109695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45943
er to golgi transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
LILRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00715783
Enhanceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carbohydrate metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.821
Follicular dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
PMC12481292-rmdopen-11-3-s002.pdf-2-GTF2I_GTF2I	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of radial diaphysis	GWASdb SNP-Phenotype Associations	1.0	1.72225
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	2.38555
choroidal sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
HCLS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056664
BRD-K36465335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27988
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
OVCA420	DepMap CRISPR Gene Dependency	1.0	5.02959
PTPN6	Pathway Commons Protein-Protein Interactions	1.0	null
lymphoma	GWASdb SNP-Phenotype Associations	1.0	0.919744
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10959171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06525
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04109
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34081
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64929
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7978
REH	DepMap CRISPR Gene Dependency	1.0	2.33245
abnormality of bone mineral density	GWASdb SNP-Phenotype Associations	1.0	1.5289
CD3D	Pathway Commons Protein-Protein Interactions	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7442
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45981
PDE6G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491127
Glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30801
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K29144638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27267
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881754
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15423
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25315
Scarlet fever	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.30458
abnormality of head or neck	GWASdb SNP-Phenotype Associations	1.0	0.334219
Medication use (thyroid preparations)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
chr6_32652534_T_C_b38	GTEx eQTL 2025	1.0	4.19086
AF-01-FE42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204696
chr6_32667428_C_T_b38	GTEx eQTL 2025	1.0	5.61823
vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932773
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9677
KIF2C	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE174498,GSE174500_0_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
increased anti-single stranded DNA antibody level	MGI Mouse Phenotype Associations 2023	1.0	null
FEV1	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.71549
BRD-K79904333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27241
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
intestinal disease	GWASdb SNP-Disease Associations	1.0	0.228898
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Autoimmune Thyroid Disease (Aitd)	DisGeNET Gene-Disease Associations	1.0	null
MCF7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.68062
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0655
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10121
BRD-K28932860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17852
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.237979
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.64742
SPTBN2	Pathway Commons Protein-Protein Interactions	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041998
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844884
CD247	Pathway Commons Protein-Protein Interactions	1.0	null
Response to hepatitis B vaccine	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24862
Lumenal side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.425
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40214
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.756726
Prestwick-674-4276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2519
abnormal spleen morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954581
CENPE	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
BRD-K28165749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05264
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996667
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42744
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7791
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.56985
PLCG1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K36923996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47461
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
Bt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCIMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534595
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5747
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874377
decreased interleukin-12 secretion	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K91282650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66457
Vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1506
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7841-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LK2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06773
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30652
IgA glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00816
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-A34826857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18098
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5846
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926011
increased urine protein level	MGI Mouse Phenotype Associations 2023	1.0	null
Nasal lavage fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
Th1 and Th2 cell differentiation	KEGG Pathways 2026	1.0	null
Interferon regulatory factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.515
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4947
Allergic disease (asthma, hay fever and/or eczema) (age of onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.3
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	2.24757
bounding membrane of organelle	GO Cellular Component Annotations 2023	1.0	null
positive regulation of leukocyte activation	GO Biological Process Annotations 2015	1.0	null
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
collagen disease	GWASdb SNP-Disease Associations	1.0	0.452186
CAPAN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49432
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07963
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H358	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64908
Generation of second messenger molecules	Reactome Pathways 2014	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2726
BRD-K38343532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.073
abnormal immunoglobulin level	MGI Mouse Phenotype Associations 2023	1.0	null
KIF3A	Pathway Commons Protein-Protein Interactions	1.0	null
Mean corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.85229
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9444
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.794
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9578
PBMC cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
tridihexethyl-5486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K52075209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25429
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.129156
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289859
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.2995
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.275156
BRD-K15427120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40227
Interferon Signaling	Reactome Pathways 2014	1.0	null
BRD-K70163662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39727
BRD-K61520618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02115
BRD-K95121261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66783
BRD-K95365728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0115
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
TNFRSF13C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546243
membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.007697
interleukin-12 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.166
NB17	DepMap CRISPR Gene Dependency	1.0	3.70888
BMP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00739486
immune system process	GO Biological Process Annotations 2015	1.0	null
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.08886
BRD-K54751614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86736
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9413
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5624-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K48389907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20977
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.18401
kidney_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0201
sulfadiazine-5523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Medial temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
Thymic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
DHRS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551066
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068928
FOLR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594466
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07634
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07491
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45481
bleomycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12648
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GNMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00535019
Small intestine mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
na90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
Immunoglobulin A vasculitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9192
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.82404
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929416
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21472896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59877
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03809
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46623934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14054
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K31780647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31718
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1389
SNUC2A	Achilles Cell Line Gene Essentiality Profiles	1.0	1.18099
artery disease	GWASdb SNP-Disease Associations	1.0	0.137712
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.167435
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
c96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
Scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.973
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2348
C1orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
positive regulation of lymphocyte activation	GO Biological Process Annotations 2023	1.0	null
golgi membrane	GO Cellular Component Annotations 2015	1.0	null
abnormal appendicular skeleton morphology	GWASdb SNP-Phenotype Associations	1.0	1.60896
BRD-K71210410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11065
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
vh2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.486053
chr6_32666554_G_C_b38	GTEx eQTL 2025	1.0	3.329
integral component of endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.167435
BRD-K36997940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20152
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8134
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7115
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
endosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K12741517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40839
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Hepatitis C	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
Lumenal side of endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GPC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601115
Multiple Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K73579545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26865
LDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.42218
Small Fiber Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
PMC9237085-41467_2022_31238_MOESM4_ESM.xlsx-Table_4_MYC_BC_signature-HGNC_symbol_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Prestwick-692-4424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0064
BRD-K18523456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2558
BRD-K22316029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39834
BRD-K80009401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10905
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
trans-Golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1879
lymphadenitis	GWASdb SNP-Disease Associations	1.0	0.794247
BRD-K17840858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10474
IZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26875
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.785
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.189
LRRFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61744
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73494324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71486
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071914
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.91881
BRD-K51275565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64095
Autoimmune disease of musculoskeletal system	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40201
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	1.68032
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
integral component of lumenal side of endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
hepatocellular carcinoma	GWASdb SNP-Disease Associations	1.0	2.2205
ORM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0068236
Endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940556
STK33_knockdown_50_GSE15151	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.46103
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
t cell receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
chr6_32648030_A_G_b38	GTEx eQTL 2025	1.0	2.6908
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K66889220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18374
NCI-H1573	GDSC Cell Line Gene Expression Profiles	1.0	1.93559
decreased tumor necrosis factor secretion	MGI Mouse Phenotype Associations 2023	1.0	null
IBMX	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18928
Narcolepsy Type 1	DisGeNET Gene-Disease Associations	1.0	null
LRIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84844
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847812
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045387
BRD-K66823946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6144
LN319	DepMap CRISPR Gene Dependency	1.0	2.29062
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
trans-Golgi network	GO Cellular Component Annotations 2025	1.0	null
GSE173169,GSE173170_0_v_1_epc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.913
EPN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00385931
decreased CD4-positive, alpha-beta T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LCK	Pathway Commons Protein-Protein Interactions	1.0	null
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
Perturb_16442_KD_IL13RA2_SRP314695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.4266
YAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00410691
abnormal spleen B cell follicle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.842
regulation of homotypic cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126504
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37625653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00378
diaphyseal sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9126
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.268091
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.123414
Hypopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.913
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.975
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9555
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Adult-Onset Still Disease	DisGeNET Gene-Disease Associations	1.0	null
White blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6301
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34143
vacuolar part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
naturally	GeneRIF Biological Term Annotations	1.0	null
Non-Alcoholic Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
antigen processing and presentation of peptide antigen	GO Biological Process Annotations 2015	1.0	null
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52489
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15468
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63888
Lung adenocarcinoma_LUAD_TCGA-55-7281-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88292241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80461
Integrin alpha4-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
IL4I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497691
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.989
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.039
Ulcerative Colitis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08043
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.8394
GSE234637_2_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7396
external side of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69066
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4723
BRD-K07431402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1156
QPCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46157
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.36293
BRD-A15330900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05502
OV7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28569
Eosinophil percentage of granulocytes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1301
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7338
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
interleukin-23 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
PHF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19943
BRD-K48528697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01853
BAS-012416453-6876	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02426
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Cytolytic granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of T cell activation	GO Biological Process Annotations 2023	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042371
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kainate selective glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
rheumatic disease	GWASdb SNP-Disease Associations	1.0	0.539099
ALK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620394
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31945
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932859
BRD-K37269981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2006
colitis	GWASdb SNP-Phenotype Associations	1.0	0.346455
DYNC1I1	Pathway Commons Protein-Protein Interactions	1.0	null
malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.239799
Parkinson's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
PIPOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00663685
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862259
PTPN11	Pathway Commons Protein-Protein Interactions	1.0	null
Mucous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
SARS-BatSRBD_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74391
Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9741
B-lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.598
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.86493
abnormality of the radius	GWASdb SNP-Phenotype Associations	1.0	1.72225
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
Cervical intraepithelial neoplasia grade 3 and invasive cervical cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.12218
6-azathymine-2466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
t cell costimulation	GO Biological Process Annotations 2015	1.0	null
abnormality of the nephron	GWASdb SNP-Phenotype Associations	1.0	1.40861
reproduction	GAD High Level Gene-Disease Associations	1.0	0.293278
ER to Golgi transport vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
IgG glycosylation	GWAS Catalog SNP-Phenotype Associations	1.0	0.405958
Pemphigus vulgaris	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.007
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
Membrane attack complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.344
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13625
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36342
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4338
NCIH1568	DepMap CRISPR Gene Dependency	1.0	3.41844
chr6_32666407_A_G_b38	GTEx eQTL 2025	1.0	6.33422
CRCGN008_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13396
Dhori Virus_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.59029
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00691
MBD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059215
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0718
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	1.0	0.866732
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7511
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5077
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7463
T84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
chr6_32659937_T_G_b38	GTEx eQTL 2025	1.0	8.24258
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
DPP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559085
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0667
positive regulation of t cell activation	GO Biological Process Annotations 2015	1.0	null
BRD-K36460699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25568
CTSO	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00039
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58455
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
ACTR1B	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the urethra	GWASdb SNP-Phenotype Associations	1.0	1.17014
GSE213988_0_v_1_rrm2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Human Papilloma Virus Infection	DisGeNET Gene-Disease Associations	1.0	null
BRD-K53458780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25595
BRD-K45799338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06135
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
BRD-K97086564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02264
A body shape index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
PDK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00624833
Anti-Glomerular Basement Membrane Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Alopecia areata	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
increased CD8-positive, alpha-beta T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14756
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
PD-1 signaling	Reactome Pathways 2014	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A8JM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1648
Inflamed seborrheic keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932859
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0505
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827672
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15566
hepatocellular carcinoma	GWASdb SNP-Phenotype Associations	1.0	2.17144
abnormal dendritic cell physiology	MGI Mouse Phenotype Associations 2023	1.0	null
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.25046
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
OAW42	DepMap CRISPR Gene Dependency	1.0	5.40478
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4009
Sero-negative rheumatoid arthritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.3699
KMBC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55163
RH18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60446
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.71
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K47441131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34269
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PLD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601096
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20892
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
RAC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511634
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866953
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Mucocutaneous Lymph Node Syndrome	DisGeNET Gene-Disease Associations	1.0	null
PMC6695281-mmc1.xlsx-Table_S6-Table_S6_Comparison_of_the_expression_levels_of_HLA_genes_between_TP53-mutated_and_TP53-wildtype_HNSCCs_and_between_HRAS-mutated_and_HRAS-wildtype_HNSCCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9056
BRD-K55852567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25333
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
JiyoyeP-2003	GDSC Cell Line Gene Expression Profiles	1.0	1.55913
C-reactive protein levels or LDL-cholesterol levels (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0619
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14982
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.7085
abnormal CD4-positive, alpha beta T cell morphology	MGI Mouse Phenotype Associations 2023	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.261072
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218441
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1476
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
clavicular sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44868
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69192
Inflammatory bowel disease	KEGG Pathways 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5635-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JK-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33337
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.139
tiaprofenic acid-4171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-DX-AB2Z-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289226
trans-Golgi network membrane	GO Cellular Component Annotations 2023	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	2.99557
sleep disturbance	GWASdb SNP-Phenotype Associations	1.0	0.488464
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.008
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24091
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.517
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormality of male external genitalia	GWASdb SNP-Phenotype Associations	1.0	0.39761
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074815
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
morphological abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.096606
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8343
gamma-delta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21518
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882871
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
positive regulation of leukocyte cell-cell adhesion	GO Biological Process Annotations 2023	1.0	null
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
long insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.959815
BRD-K28079391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.89232
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5367-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K10812033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61722
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85722
Narcolepsy	DisGeNET Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hallucinations	DisGeNET Gene-Disease Associations	1.0	null
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37854
BRD-K72452130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91916
BACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79532
DPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8838
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.689
chr6_32659664_A_C_b38	GTEx eQTL 2025	1.0	8.79671
GSE215086_5_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
Asthma and major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
BRD-K89632963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4602
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Systemic lupus erythematosus	KEGG Pathways 2026	1.0	null
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Antigen processing and presentation	KEGG Pathways 2026	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6275
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899386
L363	CCLE Cell Line Gene Expression Profiles	1.0	1.40801
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8757
HDLM2	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Histaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37187
ASPC1	DepMap CRISPR Gene Dependency	1.0	5.50277
BRD-K36197756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12866
Encephalomyelitis, Acute Disseminated	DisGeNET Gene-Disease Associations	1.0	null
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6945
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.673
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41022
Retinal vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.913
regulation of cell activation	GO Biological Process Annotations 2015	1.0	null
sleep disorder	GWASdb SNP-Disease Associations	1.0	0.852545
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4305
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K66954388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02583
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0907
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K20879770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24142
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.6336
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
lupus erythematosus	GWASdb SNP-Disease Associations	1.0	2.07237
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88805
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZAP70	Pathway Commons Protein-Protein Interactions	1.0	null
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.460724
BRD-K82658511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21925
Lung function in never smokers (low FEV1 vs high FEV1)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941382
FTC133	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68539
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.982853
Marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.945
JY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
BRD-K54179521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33306
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5743
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MHC protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
MDAMB453	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24738
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
chr6_32645347_C_T_b38	GTEx eQTL 2025	1.0	1.40445
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90482
Carcinoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.972
membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K63189715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13509
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63981
golgi apparatus part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE185519_1_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
CEACAM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599994
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00322
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.943445
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39194
Peripheral blood cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
MDAMB231	CCLE Cell Line Gene CNV Profiles	1.0	1.33916
BRD-K93693615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21656
Immunodeficiency 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
activation of immune response	GO Biological Process Annotations 2015	1.0	null
trans-Golgi network membrane	GO Cellular Component Annotations 2025	1.0	null
Brodmann area 36	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
abnormal immune system cell morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K86155080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11356
regulation of immune response	GO Biological Process Annotations 2015	1.0	null
autoimmune response	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15423
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044625
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047332
coronary aneurysm; mucocutaneous lymph node syndrome	GAD Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04203
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38839
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.423879
Yeast infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982676
KLC3	Pathway Commons Protein-Protein Interactions	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.269315
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OH-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13317726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32882
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3264
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25823
BRD-K87418665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10322
GTEX-S341-0826-SM-4AD73	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1098
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06271
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
increased IgM level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Chronic hepatitis B infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.41549
Temporal arteritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.327
Skin Diseases, Viral	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.7725
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4703
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6837
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colon sigmoideum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
urethral stenosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Sarcoma_SARC_TCGA-SG-A849-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0604
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	1.81504
CD3G	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01793276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51167
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal neuron proliferation	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K03765511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13521
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
Immunological synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982269
CD274	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K10089296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15874
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
absent spleen germinal center	MGI Mouse Phenotype Associations 2023	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03797
Ankylosing spondylitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84878
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K43936610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4848
GSE165334_3_v_1_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6194
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95233
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormality of limb bone morphology	GWASdb SNP-Phenotype Associations	1.0	1.72225
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27743
decreased regulatory T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
uroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496092
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Tuberculosis	KEGG Pathways 2026	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942198
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE193993_4_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
transport vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
Allergic sensitization	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
Dermatome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
BRD-K49981566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.463
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.293
RVH-421	GDSC Cell Line Gene Expression Profiles	-1.0	-2.09712
BRD-K97588749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10994
endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66599
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06301
PMC5577301-in-17-237-s001.xls-AR_upregulated_DEGs-Heart_GSE9377_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42601
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
interleukin-6 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.364643
623 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.576161
Cell adhesion molecule (CAM) interaction	KEGG Pathways 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26647686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02096
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35097
BRD-K38097136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37047
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0495
BRD-K11003742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01389
clathrin-coated endocytic vesicle	GO Cellular Component Annotations 2023	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41854
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
biological regulation	GO Biological Process Annotations 2015	1.0	null
MHC class II protein complex binding	GO Molecular Function Annotations 2023	1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67499
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Rheumatoid arthritis	KEGG Pathways 2026	1.0	null
BRD-K37865504_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HERPUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30907
metrifonate-5989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186460_3_v_6_baricitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MHC class II receptor activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.6552
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02686
C-reactive protein levels or total cholesterol levels (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8319
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Head and neck squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.973
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	2.09054
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07926
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3702
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41869
BRD-K56276074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97588
abnormality of finger	GWASdb SNP-Phenotype Associations	1.0	1.72225
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma	GWAS Catalog SNP-Phenotype Associations	1.0	0.085234
Costimulation by the CD28 family	Reactome Pathways 2024	1.0	null
Signal recognition particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.157
bupropion-5782	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of phalanx of finger	GWASdb SNP-Phenotype Associations	1.0	1.72225
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9072
DYNLL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SNOS-1426-SM-32PLY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
KPNYS	DepMap CRISPR Gene Dependency	1.0	6.43597
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE151612_4_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Automobile speeding propensity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K36445086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03111
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2387
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17061
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20946
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0741
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the upper urinary tract	GWASdb SNP-Phenotype Associations	1.0	0.434167
phentolamine-2323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K33064128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04881
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3646
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0804
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868831
CD276	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00816542
Respiratory bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826128
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K65086352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12495
BRD-K39979171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35764
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41749
Crypt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.821
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16524
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Lung squamous cell carcinoma_LUSC_TCGA-34-5232-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Iron status biomarkers (iron levels)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PI4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70991
abnormal lymphocyte physiology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34644
regulation of t cell activation	GO Biological Process Annotations 2015	1.0	null
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Wart	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
BRD-K28623804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41748
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932859
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99468
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902454
BRD-K05975035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27644
BRD-K92134254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15853
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chronic hepatitis C infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.53979
COV362	CCLE Cell Line Gene Expression Profiles	1.0	1.35239
PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
BRD-A03764094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01284
positive regulation of homotypic cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
tm902	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.884
BRD-K88070373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48118
Complex Regional Pain Syndromes	DisGeNET Gene-Disease Associations	1.0	null
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.83979
plasmacytoid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.63719
PCCB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00337032
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09249
BRD-K30199352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02946
mhc class ii receptor activity	GO Molecular Function Annotations 2015	1.0	null
chr6_32668369_T_C_b38	GTEx eQTL 2025	1.0	1.5328
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47122
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypersomnia	GWASdb SNP-Phenotype Associations	1.0	1.67453
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34673
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intrinsic component of endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6938
PEPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86401
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041282
mhc protein complex	GO Cellular Component Annotations 2015	1.0	null
HDAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00498932
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.108457
BRD-K06203116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04479
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8934
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	2.86296
Myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.586
MHC class II protein complex	GO Cellular Component Annotations 2023	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36342
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1501
Immunoglobulin-like fold	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K27147269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48216
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K01894374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15302
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
metaphyseal sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19755
increased susceptibility to parasitic infection	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19209
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08255
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
glomerulosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23585987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7737
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26954192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49868
transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.8384
BRD-K84077642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84338
Diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.821
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
ARL2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67186
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
antigen processing and presentation	KEGG Pathways	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.039
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10172
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.28645
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051611
abnormality of the liver	GWASdb SNP-Phenotype Associations	1.0	1.12825
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormal immunoglobulin level	GWASdb SNP-Phenotype Associations	1.0	1.21853
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29222
km3	HPA Cell Line Gene Expression Profiles	1.0	0.830862
CRCGN009_HEPG2_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09316
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
gastrointestinal inflammation	GWASdb SNP-Phenotype Associations	1.0	0.250082
Non-Rapid Eye Movement Parasomnia	DisGeNET Gene-Disease Associations	1.0	null
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.341391
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42554
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.6267
GSE86021_0_v_1_crenolanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
KIF11	Pathway Commons Protein-Protein Interactions	1.0	null
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0966
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.70372
Peripheral Arthritis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K62017257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17138
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87247
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.842
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909359
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52881
BRD-K45979235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70043
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.4674
Low density lipoprotein cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
interleukin-5 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
DOID:2939	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.398
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00774
GSE213410_0_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	1.80938
Laterodorsal tegmental nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00107
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3736
Immunoglobulin complex, circulating	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832863
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.881496
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.364643
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
BRD-K69154646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0867
Colon transversum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2806
BRD-K67090705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21645
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06953
NCIH660	CCLE Cell Line Gene Expression Profiles	1.0	2.38137
abnormality of b cells	GWASdb SNP-Phenotype Associations	1.0	0.542759
abnormal dendritic cell antigen presentation	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80443
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5773
Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
BRD-K66270896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19306
Tonsil	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Hepatitis B, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61J-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39194
Lung adenocarcinoma_LUAD_TCGA-05-4249-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Foramen magnum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
LDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70549
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-2.39898
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31834
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
placenta	HPA Tissue Gene Expression Profiles	-1.0	-1.28447
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2845
Generation of second messenger molecules	Reactome Pathways 2024	1.0	null
BRD-K35308744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13866
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.42479
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07488
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7786291-Table_1.xlsx-Table_S1-Supplementary_table_1_ETV7-related_genes_in_the_TCGA_SKCM_data_set_ETV7	Rummagene Transcription Factor Associations 2026	1.0	null
ADNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46339
Perturb_626_KD_CCND3_SRP325057	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.76221
BRD-K74651253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20724
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56936
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FtsQBL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.894
chr6_32647801_G_A_b38	GTEx eQTL 2025	1.0	16.4788
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19588
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Basal cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.715
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216933
MHC protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.958
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9481
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1101
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
clathrin-coated endocytic vesicle	GO Cellular Component Annotations 2025	1.0	null
cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
humeral sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PRRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.246
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856866
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.510707
abnormality of forebrain morphology	GWASdb SNP-Phenotype Associations	1.0	0.328207
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
Neuromyelitis optica	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1672
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
U2OS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7289
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6841
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098443
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85288
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7105
Cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.121
positive regulation of leukocyte cell-cell adhesion	GO Biological Process Annotations 2025	1.0	null
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51993
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
BRD-K42964952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13667
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41169
abnormal T cell differentiation	MGI Mouse Phenotype Associations 2023	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04881
BRD-K55510118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19406
positive regulation of T cell activation	GO Biological Process Annotations 2025	1.0	null
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
BRD-K38854468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72211
Childhood steroid-sensitive nephrotic syndrome	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.20458
clathrin-coated endocytic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
Sjogren's syndrome	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
BRD-K69423881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08514
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-geneid_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
20479250-TableS4	GeneSigDB Published Gene Signatures	1.0	null
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chronic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67435
SW1990	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
abnormality of the stapes	GWASdb SNP-Phenotype Associations	1.0	1.11116
crohn's disease	GWASdb SNP-Phenotype Associations	1.0	0.430459
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0341
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8874
IMPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71657
SLC26A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667345
Late endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
increased density of long bones	GWASdb SNP-Phenotype Associations	1.0	1.72225
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.146904
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29372
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9769
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.930116
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.48764
otosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.11116
LN235	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07815
BRD-K20028734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71651
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824921
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.2268
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4645
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Kidney Chromophobe_KICH_TCGA-KL-8329-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.986134
Pulmonary function	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16789
High-Grade Squamous Intraepithelial Lesions	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K88016677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23523
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36063
BRD-K16621460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74849
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4835
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062163
cancer	GWASdb SNP-Disease Associations	1.0	0.243227
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54101
sulfachlorpyridazine-3769	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.412377
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19456
CMLT1	DepMap CRISPR Gene Dependency	1.0	4.04492
cellular_component	GO Cellular Component Annotations 2015	1.0	null
ARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73508
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Autoimmune hepatitis in primary sclerosing cholangitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0301
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17072
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.03
Glutathione hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0147
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0141
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09734
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94777797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79892
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
KDM3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503804
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
lupus erythematosus, systemic	GAD Gene-Disease Associations	1.0	null
GSE132433,GSE132436_1_v_0_nr2f2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36096526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71761
BRD-K79665135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18446
chr6_32659745_C_T_b38	GTEx eQTL 2025	1.0	3.07995
BRD-K69184209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37783
lymphocyte costimulation	GO Biological Process Annotations 2015	1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM149PT	DepMap CRISPR Gene Dependency	1.0	4.26846
cefalexin-5250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE232624_4_v_3_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
regulation of leukocyte activation	GO Biological Process Annotations 2015	1.0	null
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85766
Stevens-Johnson syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.985
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.52433
GMEB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5537
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43572
Fc-epsilon receptor I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
endosomal part	GO Cellular Component Annotations 2015	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9797
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19775
Kidney Chromophobe_KICH_TCGA-KO-8407-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51167279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17714
PCI30	DepMap CRISPR Gene Dependency	1.0	5.18562
Persistent hepatitis B virus infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of immune system process	GO Biological Process Annotations 2025	1.0	null
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
GSE130956_0_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27782
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
chr6_32669186_C_A_b38	GTEx eQTL 2025	1.0	3.11631
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.184
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30109
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9537
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1011
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.327853
Pneumonia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
MHC class II antigen presentation	Reactome Pathways 2014	1.0	null
BRD-K16247913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30128
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.155
PMC9249059-DataSheet_1.xlsx-Table_S11-Genes_in_brown_AND_Up-related_genes_NOT_Down-related_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	1.21177
Interferon gamma signaling	Reactome Pathways 2014	1.0	null
antigen processing and presentation of exogenous peptide antigen	GO Biological Process Annotations 2023	1.0	null
postnatal growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.966
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
type 1 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	3.1343
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0687
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2204
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3W-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GMEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12045
OGDH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00421991
BRD-K61556970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25428
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0755
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2769-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67526257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14497
abnormality of digit	GWASdb SNP-Phenotype Associations	1.0	1.72225
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Latent autoimmune diabetes vs. type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	7.75229
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	0.943135
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K23578173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08053
chronic colitis	GWASdb SNP-Phenotype Associations	1.0	0.346455
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51602
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.20401
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MHC class II, alpha/beta chain, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59682
Sickle Cell Anemia_Endothelial cell_GSE9877	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.206136
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60221
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.205
GTEX-XQ3S-1326-SM-4BOPQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K93159873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17581
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57176
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54941
tetraspanin-enriched microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16433
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54988
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70308
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29545
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.8
BRD-K83877780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1894
SUPM2	CCLE Cell Line Gene Expression Profiles	1.0	1.57815
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
antigen processing and presentation of exogenous peptide antigen via MHC class II	GO Biological Process Annotations 2025	1.0	null
SW1417	Achilles Cell Line Gene Essentiality Profiles	1.0	1.3058
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05977
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6637
BRD-K10221669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20165
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97741
BRD-K00909602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.693
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.86369
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22145
Arthritis, Rheumatoid	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K73556828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1172
BRD-K10017294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27775
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95572
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5111
abnormality of the hand	GWASdb SNP-Phenotype Associations	1.0	1.72225
decreased IgG level	MGI Mouse Phenotype Associations 2023	1.0	null
Larynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.466
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.527139
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956816
Erythema	DisGeNET Gene-Disease Associations	1.0	null
late endosome membrane	GO Cellular Component Annotations 2025	1.0	null
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K89837874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55171
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18389
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102551
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.89315
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981496
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50089
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68F-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3353
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875783
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC3470785-NIHMS377161-supplement-3.pdf-106-HOXA4_HOXA4	Rummagene Transcription Factor Associations 2026	1.0	null
Asparaginase hypersensitivity in acute lymphoblastic leukemia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
BRD-K19734887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89496
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Costimulation by the CD28 family	Reactome Pathways 2014	1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18889
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Diastolic Blood Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bone disease	GWASdb SNP-Disease Associations	1.0	0.475111
spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186985
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12481
CSDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57874
Hepatobiliary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2328
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.814
mhc class ii protein complex	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A8BP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary biliary cholangitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.55229
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0
Chronic obstructive pulmonary disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27765
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881627
BRD-K16251850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30913
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44161
HIVEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98757
Lumenal side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Gestational Diabetes	DisGeNET Gene-Phenotype Associations	1.0	null
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr6_32647891_G_T_b38	GTEx eQTL 2025	1.0	8.59792
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2792
absent CD4-positive, alpha-beta T cells	MGI Mouse Phenotype Associations 2023	1.0	null
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10289
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Chikungunya Fever	DisGeNET Gene-Disease Associations	1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MHC class II protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6301
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1576
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91500340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3827
NCIH2122	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.93044
anterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04345
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.884
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3536
Dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
BICR10	DepMap CRISPR Gene Dependency	1.0	3.03684
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87317
BRD-K84391462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01852
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.41825
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Myeloid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
B cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.2034
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88939
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	2.71004
VDAC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716855
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46897
GIMEN	DepMap CRISPR Gene Dependency	1.0	4.4149
ACACA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00622042
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Buccal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
MWP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43529
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5197
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hepatitis C (spontaneous viral clearance)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.1
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052613
hepatitis b, chronic	GAD Gene-Disease Associations	1.0	null
hemolytic anemia	MGI Mouse Phenotype Associations 2023	1.0	null
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831468
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46638
cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05725
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6817
Head and neck cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.477
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
Late endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1815
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Oropharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
skin	HPA Tissue Gene Expression Profiles	1.0	1.92405
LCP2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K33940145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10987
Migraine	DisGeNET Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09297
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.269315
Sleep Disturbances	DisGeNET Gene-Phenotype Associations	1.0	null
trans-golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K35975002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00247
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57311
BRD-K25387295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46326
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
PMC3858414-NIHMS492171-supplement-1.pdf-59-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
better	GeneRIF Biological Term Annotations	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07966
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii	GO Biological Process Annotations 2015	1.0	null
Alopecia areata	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.9699
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PMC8545927__F2	PFOCR Pathway Figure Associations 2024	1.0	null
hsa-miR-654-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung cancer in ever smokers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49411
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085518
Myositis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.40969
BRD-K68330990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43484
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944122
generalized osteosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
chr6_32659398_A_C_b38	GTEx eQTL 2025	1.0	3.40395
Allergic rhinitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.0
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1216
OVMIU	DepMap CRISPR Gene Dependency	1.0	8.97862
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56612
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Sweat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44207
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937611
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
inflammation of the large intestine	GWASdb SNP-Phenotype Associations	1.0	0.346455
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.951
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40964045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12482
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7093
antigen processing and presentation	GO Biological Process Annotations 2015	1.0	null
mhc class ii protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KIF19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487584
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
Type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.83979
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.49165
GSE86021_1_v_3_crenolanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mhc protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Narcolepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59326
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.46047
BRD-K34117117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14377
BRD-K09594570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37399
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8457
chr6_32667290_T_A_b38	GTEx eQTL 2025	1.0	14.8742
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886314
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1828
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243709
Severe autoimmune type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.91549
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C75	DepMap CRISPR Gene Dependency	1.0	2.05307
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40349
LIVF001-023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0701
competitor	GeneRIF Biological Term Annotations	1.0	null
Golgi membrane	GO Cellular Component Annotations 2025	1.0	null
KIF22	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K50367303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02643
POR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580773
Spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.032
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.2831
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.24182
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3879
coated vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K93023309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17706
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69512
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43718
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6217
Autoimmune disease of cardiovascular system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.327
Oropharynx cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55032
BRD-K41645779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19415
Lung-dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.88437
Lumenal side of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.46
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
chr6_32666255_A_G_b38	GTEx eQTL 2025	1.0	3.45662
Immunoglobuin Deficiency	DisGeNET Gene-Disease Associations	1.0	null
Golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.327
KIF15	Pathway Commons Protein-Protein Interactions	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.045
antigen receptor-mediated signaling pathway	GO Biological Process Annotations 2025	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4907
Vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10172
Glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.821
ATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69133
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19513
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01671
Primary biliary cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.039
RKO	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04197
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
peptide antigen assembly with MHC class II protein complex	GO Biological Process Annotations 2023	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24554
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47433
levocabastine-2948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE185519_6_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41734
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19S-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96776591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29564
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
BRD-K26091803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32997
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS2_2019_Affy_IDs_SignalsQN-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.930108
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K27554804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29158
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mature B-cell neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
MHC class I peptide loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.055
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K90934902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81194
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856364
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914554
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05621
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
IgE levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Prostate adenocarcinoma_PRAD_TCGA-CH-5792-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Graves' disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.238
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831069
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09103
Hemidesmosome associated protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
BRD-K13038935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09986
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22014
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051221
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43607
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.821
CTSF	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of the clavicle	GWASdb SNP-Phenotype Associations	1.0	1.72225
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
T24	BioGPS Cell Line Gene Expression Profiles	1.0	1.12407
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GCSAML	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519782
BRD-K49507197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74615
BRD-K74948793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1661
Tumor necrosis factor receptor superfamily complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81445
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.327853
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
TUBA1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716558
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chronic lymphocytic leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.708
lysosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1978
BRD-K68683482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58102
abnormal diaphysis morphology	GWASdb SNP-Phenotype Associations	1.0	1.72225
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.135098
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059643
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35831
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PANC-10-05	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43289
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	1.15583
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23236
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040497
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19456
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9113
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4875
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4941
immunoglobulin production involved in immunoglobulin-mediated immune response	GO Biological Process Annotations 2023	1.0	null
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.158305
Lung cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6322
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99503
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22037
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Blood microparticle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40052
Moderate to vigorous physical activity levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
CDH24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86187
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36753
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0789
Myasthenia Gravis	DisGeNET Gene-Disease Associations	1.0	null
Intestinal immune network for IgA production	KEGG Pathways 2026	1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTSC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0423
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormality of the large intestine	GWASdb SNP-Phenotype Associations	1.0	0.218847
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.9249
Hepatitis B	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
BACE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056707
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40921
Adaptive Immune System	Reactome Pathways 2024	1.0	null
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28893
BRD-K46739745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44232
Granuloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
IgG glycosylation	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26613
Respiratory allergy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.045
physostigmine-5749	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72738
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249702
CSRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21659
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33009
PANC0813	Achilles Cell Line Gene Essentiality Profiles	1.0	1.25717
Fc receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.356
regulation of cell adhesion	GO Biological Process Annotations 2015	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831069
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991741
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981496
BRD-K03599766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26268
abnormality of the skull	GWASdb SNP-Phenotype Associations	1.0	1.40861
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
Liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.039
BRD-K97486995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37382
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067996
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116042
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7079
halflife	GeneRIF Biological Term Annotations	1.0	null
Lytic vacuole membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
IGR39	Achilles Cell Line Gene Essentiality Profiles	1.0	1.88397
abnormal renal morphology	GWASdb SNP-Phenotype Associations	1.0	1.3212
Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
Rad17 RFC-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
Cystic Fibrosis Related Diabetes	DisGeNET Gene-Disease Associations	1.0	null
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.842
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_8_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.71
Hematopoietic cell lineage	KEGG Pathways 2026	1.0	null
CBX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650019
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13101
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	2.09054
coated vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
Oxyntic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0324
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27857
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K76450502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59019
NEK11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00464853
Immunoglobulin-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE123943_1_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81S-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29745
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Sclerosing cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.975
Aa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43985
Rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.045
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	1.52393
BRD-K81949875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50311
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
KIF3B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
decreased CD8-positive, alpha-beta T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
lysosome	GO Cellular Component Annotations 2023	1.0	null
clathrin-coated vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
clathrin-coated endocytic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.11549
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05607
vacuolar part	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905126
regulation of immune response	GO Biological Process Annotations 2025	1.0	null
BRD-K25138450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32813
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.74174
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
ER to Golgi transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
oxybutynin-3168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
L428	CCLE Cell Line Gene Expression Profiles	1.0	1.50383
Anti-varicella zoster virus IgG seropositivity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
Nose disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.045
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8444
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.157499
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
endosome	LOCATE Curated Protein Localization Annotations	1.0	null
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.17896
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45153693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76734
BRD-K78245984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70777
BRD-K80336250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20391
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925551
BRD-K14399036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34908
MOLT4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45251
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
hsa-miR-647	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
KNS81	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.033
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5692-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K23857235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39051
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55894
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83895
chr6_32659351_C_T_b38	GTEx eQTL 2025	1.0	3.75106
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
KRTAP4-11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552949
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K83466873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45649
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K26383086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32038
chr6_32659042_G_T_b38	GTEx eQTL 2025	1.0	2.46095
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20748
vascular disease	GWASdb SNP-Disease Associations	1.0	0.099039
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78622
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79038
DNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93831
COPII-coated ER to Golgi transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Frailty index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.71549
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05677
systemic scleroderma	GWASdb SNP-Disease Associations	1.0	1.26855
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K47707657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0277
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7372
Abortion, Spontaneous	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25247
MM485	DepMap CRISPR Gene Dependency	1.0	4.04925
MHC class II receptor activity	GO Molecular Function Annotations 2025	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.35472
BRD-K69147598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.876
regulation of immune system process	GO Biological Process Annotations 2015	1.0	null
BRD-K52148119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04589
BRD-K16746805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02326
BRD-A20463452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62922
Conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38634
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.379881
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.58582
BRD-K27726273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03041
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9329
BRD-K64449549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17671
Gastroesophageal junction	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03586
Prostate cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
abnormal lymph node cell ratio	MGI Mouse Phenotype Associations 2023	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02233
regulation of leukocyte cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057628
CTSK	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08047
chr6_32643732_T_C_b38	GTEx eQTL 2025	1.0	3.78891
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.075
Cervix disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.075
Lymphadenitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67442425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16257
Lewy body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
YTHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42438
chr6_32646098_TAG_T_b38	GTEx eQTL 2025	1.0	3.89873
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.075
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75028
Lung squamous cell carcinoma_LUSC_TCGA-85-8350-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	2.35247
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.25576
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.265704
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2534
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K15694916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94757
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Nasal cavity disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.045
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80169
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	1.49196
cytoplasmic vesicle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
T-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.48
BRD-K30171122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11171
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855818
abnormality of facial skeleton	GWASdb SNP-Phenotype Associations	1.0	1.17014
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Skin disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K48912618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04376
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal humoral immune response	MGI Mouse Phenotype Associations 2023	1.0	null
urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.246098
Sarcoidosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K98639224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59153
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33024
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
CHCHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77288
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89445
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08812
skin	GTEx Tissue Gene Expression Profiles	1.0	1.45362
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890362
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967409
Hepatocellular carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.0902
Type 1 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K96120749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3406
Early chronic obstructive pulmonary disease in never smokers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14087001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01697
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.35229
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.075
decamethonium bromide-2933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Glycine cleavage complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.359
sclerosis of humeral diaphysis	GWASdb SNP-Phenotype Associations	1.0	1.72225
BRD-K00914921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00836
BRD-K73227372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01174
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18862
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.854418
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828803
BRD-K64862162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62339
Iga Glomerulonephritis	DisGeNET Gene-Disease Associations	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9668
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3858
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4056
Nasal vestibule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
LGMN	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52127
Kawasaki disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.21549
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.03
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
antigen processing and presentation of peptide antigen via mhc class ii	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15311
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K14431723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17777
High Grade Cervical Intraepithelial Neoplasia	DisGeNET Gene-Disease Associations	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062053
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.821
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63021
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
chr6_32655325_G_C_b38	GTEx eQTL 2025	1.0	4.09112
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47511
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37717
GEM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0074404
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6458
KIF2B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7591
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041397
BRD-K85802892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33642
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44102
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889391
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LY-01A-31R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56611
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.994411
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980507
T cell receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8179
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAG1	Pathway Commons Protein-Protein Interactions	1.0	null
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236484
KIFAP3	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6515-01A-21R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062321
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98767
BRD-K55814495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04693
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr6_32644510_A_G_b38	GTEx eQTL 2025	1.0	8.39018
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4640-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Latent autoimmune diabetes vs. type 1 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.90969
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03817
NDUFB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549857
GSE206729_5_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU16	DepMap CRISPR Gene Dependency	1.0	4.38039
early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.469203
monocyte-derived dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01749
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
functional abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.176814
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91263
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
lytic vacuole membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Integrin alpha6-beta4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1336
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71039
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871432
OLIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13044
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73089
Immunoglobulin C1-set	InterPro Predicted Protein Domain Annotations	1.0	null
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838758
Salivary gland epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
DYNLL2	Pathway Commons Protein-Protein Interactions	1.0	null
Posterior pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1598
multiple sclerosis	GAD Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Serine protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930342
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4916-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10326
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23903329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15784
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37682
Tuberculosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.8699
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8909
PMC8931289__F9	PFOCR Pathway Figure Associations 2024	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881754
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945597
Spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
urethral obstruction	GWASdb SNP-Phenotype Associations	1.0	1.72225
endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06643
GATD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04696
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89584810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39574
Acute-on-chronic liver failure in hepatitis B	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.81549
SARS-CoV_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.20462
PIP4K2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612669
Cystic Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
Tonsil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19595
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
SW1990	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
OIP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499731
chr6_32659712_A_G_b38	GTEx eQTL 2025	1.0	1.51629
PMC7029484-13041_2020_561_MOESM3_ESM.xlsx-Table_S8-Table_S8_The_extracted_upregulated_genes_in_SBMA-MNs_in_GSEA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Somnambulism	DisGeNET Gene-Disease Associations	1.0	null
pre-T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5106-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1362
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7308
SCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61983
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19588
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLC4	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04181
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3389
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.245
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.591388
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957961
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5595
clathrin-coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PECAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605018
496100666_HIP_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09826
squamous cell carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79216
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of lymphocyte activation	GO Biological Process Annotations 2015	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.3232
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.71
precuneus, right, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33534
Nephrosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
DMS273	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58655
chr6_32643512_A_G_b38	GTEx eQTL 2025	1.0	13.2174
GSE133516_0_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5233
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.8431
BRD-K40251180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55306
abnormal spleen marginal zone morphology	MGI Mouse Phenotype Associations 2023	1.0	null
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3111
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98911
GSE159049_3_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Multiple sclerosis (OCB status)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4301
Liver Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K89108431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74974
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879467
BRD-K90429860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77244
Biliary tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.975
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5218
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051295
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A3OU-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60398
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K93819193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27283
vertebral body sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52464
BRD-K29802952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32944
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	1.0	1.94178
RHOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88876
Oropharynx cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
COV318	DepMap CRISPR Gene Dependency	1.0	7.34737
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
endosome membrane	GO Cellular Component Annotations 2015	1.0	null
Thyrotoxic hypokalemic periodic paralysis and Graves disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6699
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3915
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfamerazine-3616	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCN1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053388
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08224
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.57045
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900806
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5038
BRD-K63663384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39256
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5675-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.73287
BRD-K88281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02328
confirming	GeneRIF Biological Term Annotations	1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5482
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K65361030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40137
Lysosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4148-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connective tissue disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9137
crohn's disease	GWASdb SNP-Disease Associations	1.0	0.504026
MHC classes I/II-like antigen recognition protein	InterPro Predicted Protein Domain Annotations	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3776
MAP2K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18392
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998535
BRD-K85066228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1549
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
organelle part	GO Cellular Component Annotations 2015	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K06243138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5002
BRD-K28790383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23382
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PMC11994450-44161_2025_628_MOESM3_ESM.xlsx-Supplementary_Table30-Supplementary_Table_30_Top_100_EC2_subcluster-specific_markers_in_carotid_atherosclerotic_plaque_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
encode	GeneRIF Biological Term Annotations	1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86686
CD1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00728959
BRD-K18623962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61779
BRD-K10820981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28754
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44938
abnormality of the ribs	GWASdb SNP-Phenotype Associations	1.0	1.72225
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11918
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2825
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.731
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9671
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.589
Head and neck carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.973
BRD-K63024248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40784
fosfosal-2997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22888
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98672
endocytic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66591
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GPAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39925
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S341-0426-SM-4AD5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Immune System	Reactome Pathways 2014	1.0	null
BRD-K50859531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15713
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
CHCHD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470491
NCI-H1666	GDSC Cell Line Gene Expression Profiles	-1.0	-2.39084
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.70114
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83296
CD3E	Pathway Commons Protein-Protein Interactions	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.046
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25146
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.075
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.222008
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4167-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850181
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8369
BRD-K44427106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49879
BRD-K29246335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73254
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
ICC137	DepMap CRISPR Gene Dependency	1.0	2.24504
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CSK	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
positive regulation of response to stimulus	GO Biological Process Annotations 2025	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3626
BRD-K36135420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1559
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44549
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993803
B-50 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7177
NCIH2081	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04933
Oral cavity cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.902965
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.74921
Urate levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
BRD-K39419290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08006
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Interferon Signaling	Reactome Pathways 2024	1.0	null
CP66-MEL	GDSC Cell Line Gene Expression Profiles	-1.0	-2.0457
osteosclerosis of the ulna	GWASdb SNP-Phenotype Associations	1.0	1.72225
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4722
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
decreased susceptibility to experimental autoimmune encephalomyelitis	MGI Mouse Phenotype Associations 2023	1.0	null
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02584
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47316
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29471
BRD-K01329192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.001
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
antigen processing and presentation of exogenous peptide antigen via MHC class II	GO Biological Process Annotations 2023	1.0	null
BRD-K84239940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18157
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.836333
KARPAS-299	GDSC Cell Line Gene Expression Profiles	1.0	2.22642
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
BRD-K01436366_XMD-1150_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Gastrointestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
Uterine Cervical Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
hsa-miR-148a	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the intestine	GWASdb SNP-Phenotype Associations	1.0	0.160689
GSE135350_3_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Melanoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
PDCD1LG2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09643
chr6_32659708_T_C_b38	GTEx eQTL 2025	1.0	5.89343
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8633
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981496
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7619
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062367
Allergic rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.045
SW954	DepMap CRISPR Gene Dependency	1.0	2.88332
Serum uric acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
LS-123	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54764
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47468
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18033
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040617
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04232
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	2.00576
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923715
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4353
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CORL105	CCLE Cell Line Gene Expression Profiles	1.0	3.40805
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.275156
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.241198
BRD-K03730976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09471
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
bound	GeneRIF Biological Term Annotations	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	5.06726
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ER to Golgi transport vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61416
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K72335238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04551
BRD-K21635266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35573
LC1SQ	DepMap CRISPR Gene Dependency	1.0	5.75396
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.216895
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.009294
PC14	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02794
Allergy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.35229
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.842
diffuse cerebral sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.11116
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K13817284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53596
chr6_32635710_T_C_b38	GTEx eQTL 2025	1.0	1.71869
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
Vacuolar membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25667
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
KIF20A	Pathway Commons Protein-Protein Interactions	1.0	null
Viral infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.048
Scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
Carcinoma In Situ Of Uterine Cervix	DisGeNET Gene-Disease Associations	1.0	null
BRD-K99210277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08719
chr6_32720752_T_G_b38	GTEx eQTL 2025	1.0	1.50853
Downstream TCR signaling	Reactome Pathways 2024	1.0	null
BRD-K16780806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19981
BRD-U28903152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18294
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13279
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.3621
BRD-K95443593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71316
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53595
Endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.178
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
abnormality of the humeral diaphysis	GWASdb SNP-Phenotype Associations	1.0	1.72225
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANGPTL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587935
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6275
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221479
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.8611
transport vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
MHC class II protein complex assembly	GO Biological Process Annotations 2025	1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
clathrin-coated vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48656
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2111
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15984
BRD-K62624148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92651
Lymphoid leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.708
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37269
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57961
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
BRD-K41355839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74379
er to golgi transport vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K38604123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70701
golgi apparatus part	GO Cellular Component Annotations 2015	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
EHEB	GDSC Cell Line Gene Expression Profiles	1.0	1.42786
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228773
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0
immune response-regulating signaling pathway	GO Biological Process Annotations 2015	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05338
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8713
NRIP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00889917
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03767
BRD-K13057245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22232
Oral cavity and pharyngeal cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
BRD-K83645749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32862
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2232
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17295
SCABER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44949
viral hepatitis	GWASdb SNP-Phenotype Associations	1.0	2.11688
ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.354868
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7695
BRD-K17956418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39314
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6479
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3561
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.759
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
Follicular lymphoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.9
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.5129
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6266
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91095
Adaptive Immune System	Reactome Pathways 2014	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRTAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00662222
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Germinal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.49
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06544
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057848
BRD-K39159284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81853
TPST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56041
abortion, spontaneous	GAD Gene-Disease Associations	1.0	null
hr5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
Aedesaegypti	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
chr6_32666857_C_T_b38	GTEx eQTL 2025	1.0	2.84114
TYK2_KD_GDS4754_158_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13588
ERI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00461409
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47081
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1769
GSE193993_0_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.595
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
Diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.977
KARPAS299	CCLE Cell Line Gene Expression Profiles	1.0	1.50221
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9711
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889533
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31399
KU812	CCLE Cell Line Gene CNV Profiles	1.0	1.44291
abnormality of the vertebral column	GWASdb SNP-Phenotype Associations	1.0	0.380018
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS1_2019_Affy_IDs_RA-STvsOA-ST-Unnamed_2_PAX3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18334106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52874
carboplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60138
BRD-K87213231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14377
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060257
BRD-K07409609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37839
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
RNA polymerase II termination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1847
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
IMR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
A375	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51069
GRAP2	Pathway Commons Protein-Protein Interactions	1.0	null
Allergic Asthma	DisGeNET Gene-Disease Associations	1.0	null
Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
GTEX-S95S-0426-SM-4B64I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942335
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8697
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78392
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19102
Sleep Paralysis	DisGeNET Gene-Disease Associations	1.0	null
PMC8238154__F9	PFOCR Pathway Figure Associations 2024	1.0	null
dr9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.976
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
decreased single-positive T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
NHLH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620986
SLC4A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583534
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0227
ZEB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509707
Pharynx cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
nitrendipine-3087	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831069
HPV seropositivity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4
TC106	DepMap CRISPR Gene Dependency	1.0	2.18674
Churg-Strauss syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.972
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.345516
Coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Severe aplastic anemia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903837
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10135
abnormality of cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.372031
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39913
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.16505
abnormality of the skull base	GWASdb SNP-Phenotype Associations	1.0	1.72225
Phosphorylation of CD3 and TCR zeta chains	Reactome Pathways 2014	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09451
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2072
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06372
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900558
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6403
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8118
basomedial nucleus (accessory basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941316
regulation of T cell activation	GO Biological Process Annotations 2025	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
endocytic vesicle	GO Cellular Component Annotations 2025	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.608
abnormality of the ear	GWASdb SNP-Phenotype Associations	1.0	0.353573
lytic vacuole membrane	GO Cellular Component Annotations 2025	1.0	null
Tubulointerstitium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.277
Lung function (low FEV1 vs high FEV1)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
Bullous skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.007
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8187
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin melanoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42974
diffuse mesangial sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
DNM1	Pathway Commons Protein-Protein Interactions	1.0	null
bladder carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.613183
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
peptide antigen assembly with MHC class II protein complex	GO Biological Process Annotations 2025	1.0	null
Asthma (adult onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.00969
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23338
positive regulation of leukocyte cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12338
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.0064
GSE226355,GSE226357_1_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5574-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3797
BRD-K61029307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60835
Cytokine Signaling in Immune system	Reactome Pathways 2024	1.0	null
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853744
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K06020071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12203
Knee osteoarthritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
clathrin-coated endocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73092
lung	GTEx Tissue Gene Expression Profiles	1.0	0.846363
FDFT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00342506
Squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.973
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06223
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
AKR1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08115
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.03
Chronic lymphocytic leukemia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.52218
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862395
Eosinophil percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.50458
abnormality of the upper arm	GWASdb SNP-Phenotype Associations	1.0	1.40861
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98235
lower	GeneRIF Biological Term Annotations	1.0	null
Agranulocytosis	DisGeNET Gene-Disease Associations	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048615
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	1.58367
rheumatoid arthritis	GAD Gene-Disease Associations	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autoimmune thyroiditis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.8
hepatitis b	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.580828
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BY-01A-31R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827672
BRD-K44861255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22801
Selective IgA deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7437
abnormal T cell physiology	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
astrocytes	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.932635
abnormal spleen periarteriolar lymphoid sheath morphology	MGI Mouse Phenotype Associations 2023	1.0	null
TRAPPC13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00621593
RILP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
DRD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00397302
abnormality of the male genitalia	GWASdb SNP-Phenotype Associations	1.0	0.380018
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6446
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
TAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.818
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38315
anomaly of the limb diaphyses	GWASdb SNP-Phenotype Associations	1.0	1.72225
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
Tubulin folding cofactor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67965
Hepatitis B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
BRD-K90548911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07439
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05483
BRD-K12359218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21025
HuP-T3	GDSC Cell Line Gene Expression Profiles	-1.0	-2.27852
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24047785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14226
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
Body size at age 10	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
cefmetazole-6086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TNFSF11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546966
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06561
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828513
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	2.19514
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE134986_7_v_3_oma1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K11242872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39307
chr6_32667088_G_C_b38	GTEx eQTL 2025	1.0	3.62525
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Diastolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.122996
BRD-K54939987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0378
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63385
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043882
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3927
ABCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95994
Ulcerative colitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.4301
abnormality of the uvea	GWASdb SNP-Phenotype Associations	1.0	0.415295
abnormality of the vertebrae	GWASdb SNP-Phenotype Associations	1.0	1.72225
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.74706
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881754
BRD-K25187028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53384
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr6_32656990_G_A_b38	GTEx eQTL 2025	1.0	2.82846
CCNC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595257
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210208
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08677
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
LMNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52991
Mosquito bite size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.53979
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PF-00539745-00-5974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO792	CCLE Cell Line Gene CNV Profiles	1.0	1.45082
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Lung adenocarcinoma_LUAD_TCGA-86-7714-01A-12R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Thymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
BRD-K58596567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29919
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5196
cortical sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41869
antigen processing and presentation of peptide antigen via MHC class II	GO Biological Process Annotations 2025	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.217
BRD-K95709431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06052
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214145
autoimmunity	GWASdb SNP-Phenotype Associations	1.0	1.48952
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8662
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01551
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838974
sclerosis of hand bone	GWASdb SNP-Phenotype Associations	1.0	1.72225
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7147
KIF4B	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.457
Late-onset myasthenia gravis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
BRD-K82882121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03633
TE10	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29885
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Th17 cell differentiation	KEGG Pathways 2026	1.0	null
todralazine-1841	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Familial (Fpah)	DisGeNET Gene-Disease Associations	1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5523
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75314
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	1.05424
Pancreatic islet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.186
dqa1	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76655
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal cytokine secretion	MGI Mouse Phenotype Associations 2023	1.0	null
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83122
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Juxtaparanode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
CAL148	CCLE Cell Line Gene Expression Profiles	1.0	1.40972
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31691
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9451
BRD-K13488816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47254
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
antigen processing and presentation of exogenous peptide antigen	GO Biological Process Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peptide antigen assembly with MHC protein complex	GO Biological Process Annotations 2023	1.0	null
Bone marrow stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
BRD-K73994499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45215
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2197
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Takayasu's arteritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.501
Head and neck squamous cell carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837381
Bullous pemphigoid	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
Cervical Cancer	DisGeNET Gene-Disease Associations	1.0	null
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.71
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17676
Gemini of coiled bodies	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.151
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4714
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29615
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846202
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.268
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
endocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Viral myocarditis	KEGG Pathways 2026	1.0	null
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50274
Liver Cirrhosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00816
ficolin-1-rich granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981496
PMC5007654-srep32566-s2.xls-DISEASE_GENE-POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
dr0403	GeneRIF Biological Term Annotations	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.95028
NCIH2066	CCLE Cell Line Gene Expression Profiles	-1.0	-2.98875
Kawasaki disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.676
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19588
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76672835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14271
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58924
lysosome	GO Cellular Component Annotations 2025	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3925
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19908
BRD-M01343043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02052
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
Asthma and hay fever	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.33979
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074284
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
Liver cirrhosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.039
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.20058
BRD-K56261053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01451
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932859
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Lung adenocarcinoma_LUAD_TCGA-44-2665-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8710_OE_SMAD4_SRP255626	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.51003
chr6_32644006_A_G_b38	GTEx eQTL 2025	1.0	5.97077
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6175-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEp-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8978
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02808
urethral sphincter sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05634
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13143
Lymphadenitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.676
IgA nephropathy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
Allograft rejection	KEGG Pathways 2026	1.0	null
hepatitis b	GWASdb SNP-Disease Associations	1.0	2.38233
decreased IgM level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K29183384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10412
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064967
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58963
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17386
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.339
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06964
Primary immunodeficiency disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6763
increased anti-double stranded DNA antibody level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883859
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
interferon-gamma-mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
chr6_32659340_C_A_b38	GTEx eQTL 2025	1.0	4.30803
BRD-K12986105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03111
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.353027
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.116
U87MG	DepMap CRISPR Gene Dependency	1.0	5.90719
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844652
Psmb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
BRD-K38536183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85791
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24896
Drug-induced liver injury (flucloxacillin)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.3
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06947
Peanut allergy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.922185
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
decreased susceptibility to experimental autoimmune myasthenia gravis	MGI Mouse Phenotype Associations 2023	1.0	null
palmatine-2138	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K07540687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37109
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K73635724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36841
KARPAS-422 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20030272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78842
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T5-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of lumenal side of endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.1892
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of lymphocyte activation	GO Biological Process Annotations 2025	1.0	null
BRD-K56531121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00974
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
inferior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.948121
PKMYT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057411
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6659
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33453
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32601
immune response-activating signal transduction	GO Biological Process Annotations 2015	1.0	null
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27464
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4173-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.841
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1237
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MPT synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15549
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.731
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.068743
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5164-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.107
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.834
BRD-K87159315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52106
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Endocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43054
FGFR1_knockdown_94_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.36474
endoplasmic reticulum part	GO Cellular Component Annotations 2015	1.0	null
MHC protein complex	GO Cellular Component Annotations 2023	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Psoriatic arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.406
endocytic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.062798
F2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89496
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Waist-hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
Lung adenocarcinoma_LUAD_TCGA-49-4505-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Addison Disease	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Asthma	DisGeNET Gene-Disease Associations	1.0	null
PMC11338781-Table1.XLSX-ST_2-Table_S2_The_two-sample_Mendelian_randomization_results_of_blood_GRN_and_JIA_GWAS_This_table_only_show_exposures_with_statistically_significant_MR_p-value_0_05_13_640_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91577886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07235
CTSD	Pathway Commons Protein-Protein Interactions	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Nephropathy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.5699
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19264
HDLM-2	GDSC Cell Line Gene Expression Profiles	1.0	3.60177
b82	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clathrin-coated vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.394815
liver carcinoma	GWASdb SNP-Disease Associations	1.0	2.2205
BRD-K69808609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15235
MAP3K4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00911374
Interferon regulatory factor 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.613
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTSE	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160817_4_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66179
GSE151612_0_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8876
chr6_32648025_C_T_b38	GTEx eQTL 2025	1.0	5.08196
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922033
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.952
Signal recognition particle, endoplasmic reticulum targeting	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
Neuromyelitis optica (AQP4-IgG-positive)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.43979
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28094
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
A172	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.82801
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25824
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
longer	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3429-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14210122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58155
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX6B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00504453
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.250963
BRD-K52124788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02053
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	2.09904
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0961
TGFBR3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85664
BRD-K02614439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01602
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258828
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
increased B cell number	MGI Mouse Phenotype Associations 2023	1.0	null
langerhans	GeneRIF Biological Term Annotations	1.0	null
Lymphoid follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.325
GSE202434,GSE202438_12_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the costochondral junction	GWASdb SNP-Phenotype Associations	1.0	1.72225
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
Lamina propria	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
scleroderma	GWASdb SNP-Disease Associations	1.0	0.539099
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8396
PD-1 signaling	Reactome Pathways 2024	1.0	null
BRD-K67813189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54326
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05927
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
High altitude adaptation	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
hsa-miR-3187-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
abnormal level of surface class II molecules	MGI Mouse Phenotype Associations 2023	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7162
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
B-cell lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70278
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67897
BRD-K54456668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03027
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72352
SMAD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623734
Shingles	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.21549
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.833851
BRD-K95171874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02723
chr6_32644559_G_A_b38	GTEx eQTL 2025	1.0	9.08251
BRD-K63242692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93308
sclerosis of skull base	GWASdb SNP-Phenotype Associations	1.0	1.72225
abnormality of the kidney	GWASdb SNP-Phenotype Associations	1.0	0.434167
BRD-K69521416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04524
gastrointestinal system cancer	GWASdb SNP-Disease Associations	1.0	0.433921
Fr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34878
Human T-cell leukemia virus 1 infection	KEGG Pathways 2026	1.0	null
chr6_32666326_T_C_b38	GTEx eQTL 2025	1.0	2.60703
RAJI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
TUBB6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.003558
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932859
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46184
BRD-K81939454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2955
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857527
Autoimmune disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K30863464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20763
Nodular sclerosis Hodgkin lymphoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.70969
MSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2443
Guillain-Barre Syndrome	DisGeNET Gene-Disease Associations	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.826509
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53256
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
multiple sclerosis	GWASdb SNP-Disease Associations	1.0	1.80801
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41037
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5916
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4408
craniofacial osteosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044897
Bile duct disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.975
BRD-K40745976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9301
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36318
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.280909
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.831437
Neutrophil count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.20969
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8588
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Th2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.048
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991626
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55582
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
late endosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0947
CTSA	Pathway Commons Protein-Protein Interactions	1.0	null
RES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897943
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3333
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Necrotizing Fasciitis	DisGeNET Gene-Disease Associations	1.0	null
lymphoma	GWASdb SNP-Disease Associations	1.0	1.04846
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4495
RPL29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15908
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal immune system organ morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2333
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3237
chr6_32667271_G_A_b38	GTEx eQTL 2025	1.0	6.56041
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040426
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.715
demeclocycline-3604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9362
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8669
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
systemic lupus erythematosus	GWASdb SNP-Disease Associations	1.0	2.07237
tm903	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.547
Tongue-immune cell	Tabula Sapiens Gene-Cell Associations	1.0	10.5361
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0972
BRD-K47541706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19691
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79385
Medication use (antihistamines for systemic use)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07091
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17699
skw3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
endoplasmic reticulum part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE174498,GSE174500_5_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Diamine N-acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
Systemic Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
patchy sclerosis of radial diaphysis	GWASdb SNP-Phenotype Associations	1.0	1.72225
Lymphoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
Hepatocellular carcinoma in hepatitis C infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.25229
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
all	GWASdb SNP-Phenotype Associations	1.0	0.348934
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Celiac disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.0
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	1.39396
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4567
Pemphigus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.007
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28133
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18874
Golgi apparatus subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
abnormality of the thorax	GWASdb SNP-Phenotype Associations	1.0	1.72225
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20602
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K13071687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34629
MHC class II protein complex assembly	GO Biological Process Annotations 2023	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17876
BRD-K53802078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00948
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984122
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8434-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A44A-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992089
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4616
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00358
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13377
BRD-K80306055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34478
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829764
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24214
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Peripheral blood stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.576
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61617
SKNFI	DepMap CRISPR Gene Dependency	1.0	2.62822
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr6_32667449_T_G_b38	GTEx eQTL 2025	1.0	1.37812
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.142
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979362
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phagosome	KEGG Pathways 2026	1.0	null
abnormality of the head	GWASdb SNP-Phenotype Associations	1.0	0.334219
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835147
BRD-K10775155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04038
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51212
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
TEF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0080499
BRD-K86923998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18034
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr6_32667293_T_A_b38	GTEx eQTL 2025	1.0	1.50068
Asthma	KEGG Pathways 2026	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.13183
Cataracts (operation)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94031
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14685
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43353
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75202
Lytic vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981496
proxyphylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24113
chr6_32767343_C_T_b38	GTEx eQTL 2025	1.0	1.71793
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.673
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
MORN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.006066
BRD-K55665639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33538
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Crohn Disease	DisGeNET Gene-Disease Associations	1.0	null
Steroid-Sensitive Nephrotic Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
Self-reported allergy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.41549
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L105	GDSC Cell Line Gene Expression Profiles	1.0	2.56494
BRD-K78439758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07205
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8055
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19281
GSE157296,GSE157298_4_v_5_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.867012
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K77892726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0601
protective	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K54712090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05368
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.66084
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
DTX3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84199
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79943
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lymphatic system disease	GWASdb SNP-Disease Associations	1.0	0.454009
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K37507671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07744
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3623
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Peripheral blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5142
[D]Sleep Disturbances (& [Hypersomnia] Or [Insomnia])	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09111
KDR_knockdown_119_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.65891
B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.693
IFI16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518905
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0877
abnormality of limbs	GWASdb SNP-Phenotype Associations	1.0	1.22428
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215894
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44413
peptide	GeneRIF Biological Term Annotations	1.0	null
Golgi membrane	GO Cellular Component Annotations 2023	1.0	null
LP1	CCLE Cell Line Gene Expression Profiles	1.0	1.98274
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07471
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03036
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
DYNC2LI1	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.893306
NFAT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675911
chr6_32659403_G_C_b38	GTEx eQTL 2025	1.0	3.07719
chr6_32670001_G_A_b38	GTEx eQTL 2025	1.0	3.08857
abnormality of the lower urinary tract	GWASdb SNP-Phenotype Associations	1.0	1.17014
aortic root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.880781
NB5	DepMap CRISPR Gene Dependency	1.0	2.14734
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02985
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
GSE186647,GSE217288_1_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86097
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77337
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01126
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7553
Endocrine gland cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
laminin-6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.995
interleukin-4 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.206
SCC-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K53662389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67871
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
DNM3	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91543
sclerosis of finger phalanx	GWASdb SNP-Phenotype Associations	1.0	1.72225
Bronchial disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.226
GTEX-NPJ8-2426-SM-3MJHL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K71138333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50429
Salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.464
Cutaneous Melanoma	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the metaphyses	GWASdb SNP-Phenotype Associations	1.0	1.72225
Central nervous system vasculitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.327
Lung adenocarcinoma_LUAD_TCGA-86-8278-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
decreased IgG1 level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15482
immune response	GO Biological Process Annotations 2015	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48038
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
Mouth disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.198
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24539
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.039
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABCG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00493795
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.045
trans-Golgi network membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6966
RIDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513512
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
increased anti-erythrocyte antigen antibody level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
immune system disease	GWASdb SNP-Disease Associations	1.0	0.316388
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.075
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33424
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K37684893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.30587
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZMYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70065
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Autoimmune disease of central nervous system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.327
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
membrane part	GO Cellular Component Annotations 2015	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0672
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Pursuit maintenance gain	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
CCDC85B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0969
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K66030669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40595
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
Inner ear disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226926
BRD-K89199943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20311
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Celiac Disease	DisGeNET Gene-Disease Associations	1.0	null
Glucosuria (moderate to severe)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.2699
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.135888
Eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.427
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879326
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6792-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.8639
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.71
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942339
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
lysosomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
squamous epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PDE3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513228
Labial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39997
Cervix Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
interstitial cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.822488
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4037
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
intrinsic component of organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
LAMA-84	GDSC Cell Line Gene Expression Profiles	1.0	1.58082
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25566
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961244
Plantar warts	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.20969
BRD-K71296038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1724
TCR signaling	Reactome Pathways 2014	1.0	null
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15423
nipecotic acid-5999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal bone structure	GWASdb SNP-Phenotype Associations	1.0	1.5289
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39459
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5963
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.442
CDK6_knockdown_93_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76437
Rheumatic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.973
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4438
PLK3_knockdown_121_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.85809
BRD-K58028568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.665
morphological abnormality of the middle ear	GWASdb SNP-Phenotype Associations	1.0	1.11116
Squamous cell lung carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37895
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.115
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191666
intrinsic component of organelle membrane	GO Cellular Component Annotations 2015	1.0	null
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Autoimmune disease of the nervous system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.327
sclerotic forearm bones	GWASdb SNP-Phenotype Associations	1.0	1.72225
increased CD4-positive, alpha-beta T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Common variable immunodeficiency 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.450821
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56399425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15852
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5634
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
insulitis	MGI Mouse Phenotype Associations 2023	1.0	null
Genital mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SP-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr6_32652946_G_T_b38	GTEx eQTL 2025	1.0	4.32811
BRD-K48332223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11063
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41913
lumenal side of endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
lytic vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.989938
clathrin-coated endocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SNU201	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86472
SW1990	DepMap CRISPR Gene Dependency	1.0	6.81995
Basophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
BRD-K91820608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88489
pioglitazone-5972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K06029218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03709
Clitoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.79029
regulation of cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	1.04139
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84775
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8523
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.93071
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26226
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86638
PRKAA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00430654
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
PFEIFFER	CCLE Cell Line Gene Expression Profiles	1.0	1.79403
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945398
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1459
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
BRD-K52049165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00593
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13648
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
abnormality of the forearm	GWASdb SNP-Phenotype Associations	1.0	1.72225
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924295
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MN-01A-22R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3796
narcolepsy	GWASdb SNP-Disease Associations	1.0	1.77917
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058506
JVM2	CCLE Cell Line Gene Expression Profiles	1.0	1.64698
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904054
immune response-regulating cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
abnormality of limb bone	GWASdb SNP-Phenotype Associations	1.0	1.52267
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977775
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36213
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
ICC12	DepMap CRISPR Gene Dependency	1.0	2.29539
urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.545342
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61854
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855405
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85697
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
sclerosis of foot bone	GWASdb SNP-Phenotype Associations	1.0	1.72225
diaphyseal sclerosis of the upper limbs	GWASdb SNP-Phenotype Associations	1.0	1.72225
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982269
PMC11225427-13058_2024_1861_MOESM2_ESM.xlsx-Supplemental_Table_S4-Supp_Table_S4_AR_mediated_PGx-eQTL_genes_and_associated_with_all_GWAS_traits_from_GWAS_catalog_AR	Rummagene Transcription Factor Associations 2026	1.0	null
guaifenesin-4549	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.627
Centrum semiovale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
mesangial abnormality	GWASdb SNP-Phenotype Associations	1.0	1.72225
Membranous Glomerulonephritis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K44131977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1695
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
NOMO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02494
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
INHBC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591286
C21orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30445
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.84755
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89114
regulation of T cell activation	GO Biological Process Annotations 2023	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17187
Myeloid cell_Skin_Human	CellMarker Gene-Cell Type Associations	1.0	null
NP8	DepMap CRISPR Gene Dependency	1.0	4.94065
Anti-Epstein-Barr virus nuclear antigen (EBNA) IgG levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48109
BRD-K27529556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50441
intrinsic component of endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatitis B	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.048
aminohippuric acid-6453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882199
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
occipito-temporal gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.948145
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36552
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857527
chr6_32663718_T_C_b38	GTEx eQTL 2025	1.0	5.88806
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74771
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1117
abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.334664
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057442
BRD-K52017042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14297
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8195
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26048
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.19202
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K19457629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10999
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7597
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19104
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0529
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.998
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hsa-miR-942	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K03855997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46521
17638852-Table3	GeneSigDB Published Gene Signatures	1.0	null
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
liver cancer	GWASdb SNP-Disease Associations	1.0	1.77016
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15459
BRD-K76251351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47709
coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984788
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
immunoglobulin mediated immune response	GO Biological Process Annotations 2023	1.0	null
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
clemastine-2412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
T3M4	CCLE Cell Line Gene Expression Profiles	1.0	1.47001
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02881
abnormal B cell physiology	MGI Mouse Phenotype Associations 2023	1.0	null
17638852-Table6	GeneSigDB Published Gene Signatures	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210305
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Tonsillectomy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
BRD-K36575476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14601
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16489
MKN45	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76384
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.254536
BRD-K39411863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32303
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918208
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04997
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5171
CADOES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23623
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU1919	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57812
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.759
Rectum adenocarcinoma_READ_TCGA-EI-6917-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
KIF3C	Pathway Commons Protein-Protein Interactions	1.0	null
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23465
Mucocutaneous Lymph Node Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8574
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040776
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15056
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917004
langerhans cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.608527
RBM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
BRD-K47415214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56642
Waist circumference adjusted for body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
systemic lupus erythematosus	GWASdb SNP-Phenotype Associations	1.0	2.04537
Crustacean allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
Graft-versus-host disease	KEGG Pathways 2026	1.0	null
BRD-K90694955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.411
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	9.9699
Integral component of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Sarcoma_SARC_TCGA-DX-A3U8-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6479
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061228
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8492
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Peripheral blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Translocation of ZAP-70 to Immunological synapse	Reactome Pathways 2014	1.0	null
Mitochondrial heteroplasmy measurement	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.23979
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myocarditis	DisGeNET Gene-Disease Associations	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.094
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7609
abnormality of the middle ear ossicles	GWASdb SNP-Phenotype Associations	1.0	1.11116
Vasculitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.972
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31182
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K39794286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31388
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2962
Addison's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53113
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.36
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931153
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.8
Gut cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
BRD-K99302735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46809
Asthma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.226
clathrin-coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K96416345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29003
GSE233183,GSE233187_2_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Translocation of ZAP-70 to Immunological synapse	Reactome Pathways 2024	1.0	null
chr6_32655706_A_C_b38	GTEx eQTL 2025	1.0	8.47438
KIF26A	Pathway Commons Protein-Protein Interactions	1.0	null
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59797
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
antigen processing and presentation of exogenous peptide antigen via mhc class ii	GO Biological Process Annotations 2015	1.0	null
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4871
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
b65	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-612	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K63154470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07908
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
type i diabetes mellitus	KEGG Pathways	1.0	null
Plasmacytoid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.879647
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7122
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42052
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.842
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881754
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88321
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MU-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967764
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thymic medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
Total cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2301
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4837
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51546
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4753
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
hsa-miR-3189-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.21707
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911368
chr6_32645273_G_A_b38	GTEx eQTL 2025	1.0	3.35499
PDCD1	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
postcentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937041
side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.007697
KIF2A	Pathway Commons Protein-Protein Interactions	1.0	null
Hypothyroidism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.3301
Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of upper limb bone	GWASdb SNP-Phenotype Associations	1.0	1.72225
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr6_32659383_A_G_b38	GTEx eQTL 2025	1.0	5.01658
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of lymphocytes	GWASdb SNP-Phenotype Associations	1.0	0.403699
BRD-K00083518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08053
GSE193993_0_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.62991
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.067
DAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00377743
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
B-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04317371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80308
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84276
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.0699
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.084831
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IL17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
patchy changes of bone mineral density	GWASdb SNP-Phenotype Associations	1.0	1.72225
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02171
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.007
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15728
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal immune system physiology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869552
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K76400756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00407
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
BRD-K09819684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22996
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875656
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09144
BRD-K53717076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4898
BACH1	ChEA Transcription Factor Targets	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882577
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939263
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.63051
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.517
A1BG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657977
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.197
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051097
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056881
Narcolepsy-Cataplexy Syndrome	DisGeNET Gene-Disease Associations	1.0	null
KIF23	Pathway Commons Protein-Protein Interactions	1.0	null
Biliary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963185
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.565772
BRD-K67597437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46278
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5119
Herpes simplex virus 1 infection	KEGG Pathways 2026	1.0	null
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
BRD-K90358614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09526
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Oral cavity cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.198
viral infectious disease	GWASdb SNP-Disease Associations	1.0	1.01351
Masseter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
Autoimmune thyroid disease	KEGG Pathways 2026	1.0	null
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8433
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5052
BRD-K06428422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58531
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1028
integral component of endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36818
rj2.2.5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
lysosomal membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K11671824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38912
Autoimmune disease of skin and connective tissue	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
SW156	DepMap CRISPR Gene Dependency	1.0	2.31999
Rheumatoid arthritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.31549
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.281
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.993613
ER membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.081
SK-MEL-28	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54548
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311355
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Ebola virus infection in host	WikiPathways Pathways 2024	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7834
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
sclerosis of metaphyses of the upper limbs	GWASdb SNP-Phenotype Associations	1.0	1.72225
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K91593159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30041
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04308
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05378
TMIGD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057205
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.93201
Sveinsson Chorioretinal Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Type 1 diabetes (age at diagnosis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K91268803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56142
non-Hodgkin lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
KIF18A	Pathway Commons Protein-Protein Interactions	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0296
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887139
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6642
COPII-coated ER to Golgi transport vesicle	GO Cellular Component Annotations 2023	1.0	null
Hypnozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
Kidney Chromophobe_KICH_TCGA-KM-8477-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
boldine-2148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69512
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912939
processed	GeneRIF Biological Term Annotations	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7587
Lymphocyte percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.15799
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03723
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
antigen processing and presentation of peptide antigen via MHC class II	GO Biological Process Annotations 2023	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4074
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23928
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.759
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15258
BRD-K07870648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35361
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.0593
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857527
IL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00545336
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.149702
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Type 1 diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.507
Extracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MHC class II protein complex binding	GO Molecular Function Annotations 2025	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Coronary Aneurysm	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
ZNF776	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71584
PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963148
SW626	DepMap CRISPR Gene Dependency	1.0	3.04607
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26508
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4365
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.224547
reduced fertility	MGI Mouse Phenotype Associations 2023	1.0	null
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20255
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K35945596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1814
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83097
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lumenal side of endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
Tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
BZW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67921
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12249
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.404797
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6137
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.719
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15423
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2912
Interferon gamma signaling	Reactome Pathways 2024	1.0	null
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1912
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.527
vacuolar membrane	GO Cellular Component Annotations 2015	1.0	null
dq8	GeneRIF Biological Term Annotations	1.0	null
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067851
hsa-miR-152	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5219
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26434
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79666
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2006
OVE-208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32604
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Histiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5526
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46027
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052008
MHC class II antigen presentation	Reactome Pathways 2024	1.0	null
Leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.708
BRD-K66207462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53391
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.9939
Locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
CCL19 levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28885073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37602
BRD-K63163033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35756
dissociation	GeneRIF Biological Term Annotations	1.0	null
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19566
SCABER	DepMap CRISPR Gene Dependency	1.0	3.46782
BRD-K94109423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04815
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844652
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of b cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.542759
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70368
chronic hepatitis	GWASdb SNP-Phenotype Associations	1.0	2.11688
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64004
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3275
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62S-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83090041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06263
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03636
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
infection	GAD High Level Gene-Disease Associations	1.0	0.295739
Serum IgE levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929244
Auditory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.655
Hepatitis B	DisGeNET Gene-Disease Associations	1.0	null
icSARA deltaORF6_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70814
SARS-CoV MA15_Day4-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.39833
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1983
C8orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056113
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2223
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3894
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	1.0164
Nasopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85887470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65533
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.075
eb185	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
DPM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518312
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
SNU466	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03608
BRD-K90133770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09532
BRD-K51335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07228
BRD-K07959057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06402
BRD-K05704547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21711
SYK_KD_GDS3609_440_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11182
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218613
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55165
PMC11265019-13048_2024_1474_MOESM4_ESM.docx-0-ZHX3_ZHX3	Rummagene Transcription Factor Associations 2026	1.0	null
chr6_32652754_T_C_b38	GTEx eQTL 2025	1.0	1.91086
integral component of organelle membrane	GO Cellular Component Annotations 2015	1.0	null
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81F-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.83001
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
alpha-beta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.501
MHC class II protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.015
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16507
Childhood ear infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.922185
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23734
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956154
APOC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00616045
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
Endocytic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PBX1	ChEA Transcription Factor Targets	1.0	null
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.00022
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250942
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K25931705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04063
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6477
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39194
SK-MEL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37743
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.48228
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24084
Red blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.10969
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34746
BRD-K07781799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66051
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
Downstream TCR signaling	Reactome Pathways 2014	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4228
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02643
hematologic cancer	GWASdb SNP-Disease Associations	1.0	1.39396
Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the choroid	GWASdb SNP-Phenotype Associations	1.0	0.79737
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866041
Nephrotic syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
OSBPL1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCI-AML2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93754
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870473
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.985
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26497
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7964
Staphylococcus aureus infection	KEGG Pathways 2026	1.0	null
CCAAT-binding factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.934
hepatitis	GWASdb SNP-Phenotype Associations	1.0	2.35031
MHC class Ib protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9941
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20112
Kawasaki disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85879
EM2	CCLE Cell Line Gene CNV Profiles	1.0	2.28101
protein complex	GO Cellular Component Annotations 2015	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	1.0	5.1556
clotrimazole-3166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.905
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00169
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98945
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
TRAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590392
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247223
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
er to golgi transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875324
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Cervical cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
BRD-K87053028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59232
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin-langerhans cell	Tabula Sapiens Gene-Cell Associations	1.0	1.30562
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
IgG levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0398
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1000-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21178
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A6BE-01A-41R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6638
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.59627
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5662
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867833
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2207
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.0634
PPARA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607194
CRCGN014_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06989
KIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
RACGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.78889
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03475
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Alveolar mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
chr6_32644511_A_G_b38	GTEx eQTL 2025	1.0	3.36789
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922027
Laryngeal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052901
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929038
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.96928
MFE-296	GDSC Cell Line Gene Expression Profiles	-1.0	-2.14047
Toxoplasmosis	KEGG Pathways 2026	1.0	null
A204	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57478
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11296
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peak expiratory flow	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.45229
Juvenile rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08612
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61296
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03847
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67395
Set3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
coated vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
Esophageal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.684
Immunoglobulin/major histocompatibility complex, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ITGA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0047796
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.75142
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.0564
PMC9335103__F4	PFOCR Pathway Figure Associations 2024	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2222
Cardiomyopathy_Myocardial tissue_GSE5406	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.52526
EBV-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal immune system morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
inflammatory bowel disease	GWASdb SNP-Disease Associations	1.0	0.323885
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PMC12454715-13555_2025_1471_MOESM1_ESM.pdf-34-HOXA5_HOXA5	Rummagene Transcription Factor Associations 2026	1.0	null
PTP4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584933
BRD-K14780713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13492
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.02
UNG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520019
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11315
C1QTNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06698
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
BRD-K04363234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17281
FD-20-OG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245157
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of upper limb metaphysis	GWASdb SNP-Phenotype Associations	1.0	1.72225
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
be11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
Infiltrating Cervical Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
immune response-activating cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6582
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15163
Sequoiosis	DisGeNET Gene-Disease Associations	1.0	null
Ragulator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
DDR1_knockdown_169_GSE39207	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.81015
neoplasm of the liver	GWASdb SNP-Phenotype Associations	1.0	2.17144
decreased susceptibility to parasitic infection	MGI Mouse Phenotype Associations 2023	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57481
positive regulation of immune system process	GO Biological Process Annotations 2015	1.0	null
Pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.179
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
abnormality of the rib cage	GWASdb SNP-Phenotype Associations	1.0	1.72225
decreased susceptibility to autoimmune disorder	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K53552465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43909
Malignant Tumor Of Cervix	DisGeNET Gene-Disease Associations	1.0	null
BRD-K13275849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17544
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Emphysema imaging phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
BRD-K43159427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15185
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46493
BRD-K65875972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05286
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-genename_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
monocyte-derived dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.666809
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
Sputum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
ZFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57356
BRD-K27226238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39072
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
early endosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.02684
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9742
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5904
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lysosomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
positive regulation of cell activation	GO Biological Process Annotations 2015	1.0	null
Liver Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K51898276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01996
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.715
CTSB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Enteric fever	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GO-06A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966178
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.619442
SPOTS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.887
TCR signaling	Reactome Pathways 2024	1.0	null
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Influenza A	KEGG Pathways 2026	1.0	null
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.193404
BRD-K06203932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79624
calvarial osteosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
BRD-K85395981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04025
BRD-K30761927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04049
Lung adenocarcinoma_LUAD_TCGA-64-1680-01A-02R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.025
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.847964
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912939
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92922
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6805
BRD-K89724519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55338
Peripheral blood lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
BRD-K05796780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04351
Multiple sclerosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.0
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48446
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48334
trans-Golgi network	GO Cellular Component Annotations 2023	1.0	null
HCT116	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27615
CORL23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.37186
hsa-miR-541	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
chr6_32652570_C_CT_b38	GTEx eQTL 2025	1.0	1.84712
Asthma (childhood onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.9
BRD-K94411351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04739
Mesothelioma_MESO_TCGA-SH-A7BC-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.351555
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04445
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063951
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_6_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.075
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.047
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40862705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55994
BRD-K60188481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61417
Diabetes Mellitus, Type 1	dbGAP Gene-Trait Associations	1.0	2.31725
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
molecule	GeneRIF Biological Term Annotations	1.0	null
chr6_32655653_G_A_b38	GTEx eQTL 2025	1.0	4.25571
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1612
BRD-K21176869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.187
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
Ankylosing Spondylitis	DisGeNET Gene-Disease Associations	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5306
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5601
MYOM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573425
Integumentary system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.154
rate	GeneRIF Biological Term Annotations	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3302
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13012
HUH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95336
Shrimp allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27264
ACSM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81546
Retrotransposon nucleocapsid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00149
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08518
Hepatitis B, Chronic	dbGAP Gene-Trait Associations	1.0	1.63528
BRD-K46308702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82481
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922021
testis_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
chr6_32667977_G_T_b38	GTEx eQTL 2025	1.0	2.91161
Graves Disease	DisGeNET Gene-Disease Associations	1.0	null
CYP1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00556016
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07963
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8345
Glucosuria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7301
Cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.975
BRD-A55411938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01161
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6597
Aedesalbopictus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877532
BRD-K67409155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62774
BRD-K16064200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36884
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.913
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	3.24099
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90313
LIN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38715
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69984954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31026
Dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.007
BRD-K66282601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05849
BRD-K36282114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92916
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.189
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6303
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Medication use (drugs used in diabetes)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	7.45229
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.464465
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
endocytic vesicle	GO Cellular Component Annotations 2023	1.0	null
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
late endosome	GO Cellular Component Annotations 2025	1.0	null
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62943
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B6-01A-21R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40116023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51276
than	GeneRIF Biological Term Annotations	1.0	null
Hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.966
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76829
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.333991
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19873
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883761
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26958
systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.164786
Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.612
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical Intraepithelial Neoplasia	DisGeNET Gene-Disease Associations	1.0	null
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222833
BRD-K30917841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25655
Leishmaniasis	KEGG Pathways 2026	1.0	null
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	2.15331
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
Schwann cell microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88321
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2361
BRD-K33891642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08615
positive regulation of cell adhesion	GO Biological Process Annotations 2015	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93255
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.78995
tacrolimus-284	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PTPRC	Pathway Commons Protein-Protein Interactions	1.0	null
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276929
neoplasm of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.391859
single-stranded DNA-binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.081
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19679
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
hladqa2	GeneRIF Biological Term Annotations	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6717
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15249
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01513
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16652
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53234
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99942
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K65496998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10779
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13407
lysosomal membrane	GO Cellular Component Annotations 2025	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Langerhans cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52576
abnormality of the cerebrum	GWASdb SNP-Phenotype Associations	1.0	0.328207
GSE94849_3_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Complement component C1q complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.581
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.654
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03909
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052468
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18205
Epstein-Barr virus infection	KEGG Pathways 2026	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35425
multivesicular body	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE215086_4_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04635516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30279
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33856
Juvenile rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13265
MTA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618887
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.186657
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5498
Intrinsic component of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.069
hsa-miR-4261	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
cell adhesion molecules	KEGG Pathways	1.0	null
Gut mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.1208
Thrombocytopenia	DisGeNET Gene-Phenotype Associations	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5118
class	GeneRIF Biological Term Annotations	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24332
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.46617
Hepatitis B	GWAS Catalog SNP-Phenotype Associations	1.0	1.37564
Lung adenocarcinoma_LUAD_TCGA-50-5941-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16036
premature death	MGI Mouse Phenotype Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2876
arthritis	GWASdb SNP-Disease Associations	1.0	1.35022
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949121
Cataplexy	DisGeNET Gene-Disease Associations	1.0	null
BRD-K03339354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13022
93T449	DepMap CRISPR Gene Dependency	1.0	2.34346
BRD-K22443456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29055
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	2.28469
Lung function (FEV1/FVC)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.6
PMC4521181-oncsis201520x8.pdf-150-MTERFD3_MTERF2	Rummagene Transcription Factor Associations 2026	1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931983
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85478
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Proteinuria	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
nephrosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35137
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3182
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.759
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3627
dohh2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
abnormality of long bone morphology	GWASdb SNP-Phenotype Associations	1.0	1.72225
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
guanyl-nucleotide exchange factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.055
Itch intensity from mosquito bite adjusted by bite size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.02218
diabetes mellitus, type 1	GAD Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48999
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976166
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
central medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.833415
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45734
BRD-K05414181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14466
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.35371
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
racecadotril-5755	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
postcentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947233
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.15608
BRD-K61795707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64737
Eczema	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040545
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973631
abnormal response to transplant	MGI Mouse Phenotype Associations 2023	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	2.31862
abnormality of the middle ear	GWASdb SNP-Phenotype Associations	1.0	0.459734
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078534
BRD-K94293016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21014
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8152
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PM-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981496
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881591
WM88	DepMap CRISPR Gene Dependency	1.0	2.65773
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Type I diabetes mellitus	KEGG Pathways 2026	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949057
BRD-K49490091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24622
Lymph node disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.007
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
endocytic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K01643633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07805
TXN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564127
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52967
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04116
antigen receptor-mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.51492
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4162
Systemic scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.973
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46353
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
BRD-K88856685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40645
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15607
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.77556
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12238
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.955
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K62288678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37136
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GSE160817_0_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35796
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3625
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chronic hepatitis B infection	GWAS Catalog SNP-Phenotype Associations	1.0	1.18976
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74825
golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.918
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAT	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K19590405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0602
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48556518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03618
Takayasu arteritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.968191
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9992
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7659
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85154
cell part	GO Cellular Component Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28093
BRD-K78647367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79817
CCDC158	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548949
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42368
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95698
BRD-K85636571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03883
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Multiple Sclerosis	dbGAP Gene-Trait Associations	1.0	1.19896
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.65081
non-hodgkin lymphoma	GWASdb SNP-Disease Associations	1.0	0.755533
Asthma or allergic disease (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.40969
CDK8_knockdown_88_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.60594
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5217
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961244
PAK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579717
endocytic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
LGLL - Large granular lymphocytic leukemia_Peripheral blood mononuclear cell_GSE10631	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53779
BRD-K96133500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30944
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.927
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8462
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0922
Rheumatic heart disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
abnormal external genitalia	GWASdb SNP-Phenotype Associations	1.0	0.39761
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4823830-ncomms11171-s2.xlsx-GATA3_repressed_genes-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872629
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.54836
Elementary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
BRD-K13898728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10863
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20218
NCIH1693	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77435
nefopam-2355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67817697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2108
Dendritic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4176-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11277
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.4405
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8125
trans-golgi network membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45166
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65329
abnormality of the glomerulus	GWASdb SNP-Phenotype Associations	1.0	1.40861
abnormality of the humerus	GWASdb SNP-Phenotype Associations	1.0	1.72225
BRD-K21215763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89289
ZR7530	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09214
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
Alopecia areata	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.981
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.733
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17232330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31362
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
BRD-K11105500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35783
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4033
JHH7	DepMap CRISPR Gene Dependency	1.0	3.00037
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5293
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959439
EHEB	CCLE Cell Line Gene Expression Profiles	1.0	1.99355
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9231
Duodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046494
Lymph_Node-mature conventional dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.128098
BRD-K82504878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05939
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations	1.0	1.10796
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23961
antigen processing and presentation of exogenous peptide antigen	GO Biological Process Annotations 2015	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32647
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
UBTFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22889
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34508
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Lupus Erythematosus, Systemic	dbGAP Gene-Trait Associations	1.0	1.22015
Epstein-Barr virus immune response (EBNA-1)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.936
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54046
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01316
signal transduction	GO Biological Process Annotations 2015	1.0	null
KIAA0040	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78191
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05049
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840329
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06457
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19412
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24397
Perturb_78_KD_BAP18_SRP074464	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.55427
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
cytokine-mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89187
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.007
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4129
RNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
B-lymphoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
MHC class II protein complex	GO Cellular Component Annotations 2025	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5357
Lung squamous cell carcinoma_LUSC_TCGA-22-4596-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5305
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887366
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
B4GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74072
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
anomaly of the upper limb diaphyses	GWASdb SNP-Phenotype Associations	1.0	1.72225
abnormality of humoral immunity	GWASdb SNP-Phenotype Associations	1.0	0.372031
Lung squamous cell carcinoma_LUSC_TCGA-34-5239-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7222
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
MHC protein complex	GO Cellular Component Annotations 2025	1.0	null
ERBB3_knockdown_65_GSE19921	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.43473
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899202
abnormal CD4-positive, alpha-beta T cell physiology	MGI Mouse Phenotype Associations 2023	1.0	null
integral component of organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74179
transport vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
BRD-K87794979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53108
GSE160817_0_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.785574
abnormality of forearm bone	GWASdb SNP-Phenotype Associations	1.0	1.72225
Bronchoalveolar lavage fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
KYSE-140	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50055
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
increased double-negative T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
PANX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10941
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.3414
Pulmonary function (smoking interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
costochondral joint sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.72225
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.975662
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.7265
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19449
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	2.2352
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37559
Heavy chain immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
BRD-K98140933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40768
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4836
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.80005
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61617
BRD-K95651150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35421
496100490_HIP_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59658
Aortic Root Dilatation	DisGeNET Gene-Disease Associations	1.0	null
Helicobacter pylori OMP antibody levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.91549
Immune system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.935763
BICR18	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4076
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.38666
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
kawasaki disease	GWASdb SNP-Disease Associations	1.0	0.794247
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4655
Skin-cd1c-positive myeloid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.529637
disease of metabolism	GWASdb SNP-Disease Associations	1.0	1.11707
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
peptides	GeneRIF Biological Term Annotations	1.0	null
HEC1A	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01715
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC8776696__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Immune System	Reactome Pathways 2024	1.0	null
hsa-miR-148b	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
COPII-coated ER to Golgi transport vesicle	GO Cellular Component Annotations 2025	1.0	null
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39569
Diabetic retinopathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.913
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4717
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
DYNC2H1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Systemic sclerosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.35229
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4324
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53309
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77859
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1129
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.972
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	2.2353
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.91675
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2035
BRD-K94442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14443
KIF4A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Asthma (moderate or severe)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.12218
Cytokine Signaling in Immune system	Reactome Pathways 2014	1.0	null
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
EB1	CCLE Cell Line Gene Expression Profiles	1.0	1.54035
PMC8410861-41467_2021_25544_MOESM32_ESM.xlsx-MCR-MCR_cells_-_DGE_iGCA_testis_vs_adult_testis_from_GSE112013_and_GSE124263_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01335