association	dataset	threshold value	standardized value
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97547
monocarboxylic acid catabolic process	GO Biological Process Annotations 2023	1.0	null
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20174
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substrate	GeneRIF Biological Term Annotations	1.0	null
GSE160373_1_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998426
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5190-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02219
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
amino acid catabolic process	GO Biological Process Annotations 2023	1.0	null
Peroxisomal acyl-CoA oxidase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01461
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33668
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959609
oxalate metabolic process	GO Biological Process Annotations 2025	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
ESR1_T47D_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967402
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27804
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06987
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885723
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59958
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27111
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98968
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3368
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8801
Ureterolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
ML-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57997
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.902429
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10029
SAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.113
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3393
context	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.57947
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37783
NXT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49864
GSE152379_0_v_4_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
PRICKLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50523
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5032
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48407
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PARP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17428
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30789
Lung adenocarcinoma_LUAD_TCGA-73-4677-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-acetylneuraminate metabolic process	GO Biological Process Annotations 2023	1.0	null
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36612
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94692
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874899
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20359
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
(R,S)-4-hydroxy-2-oxoglutarate aldolase activity	GO Molecular Function Annotations 2025	1.0	null
GSE200352_4_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCCSUP	DepMap CRISPR Gene Dependency	1.0	2.51851
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042981
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4344
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6903
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.05423
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.92694
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931412
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16943
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12568
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.72306
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11875
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02925
ABITRAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36638
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04015
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18676
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55G-1126-SM-48FDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59506
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919922
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
ZNF358	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13211
RERFGC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44005
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86238
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01493
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41869
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.76616
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49233
liver_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.13557
UMRC3	DepMap CRISPR Gene Dependency	1.0	2.33427
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61228
4-hydroxyproline catabolic process	GO Biological Process Annotations 2015	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73635
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68946
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13514
Lung adenocarcinoma_LUAD_TCGA-95-7567-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BICR6	DepMap CRISPR Gene Dependency	1.0	2.19682
STARD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11193
Scutellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65673
NFIC	ENCODE Transcription Factor Targets	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5155
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992749
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR1	ENCODE Transcription Factor Targets	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.88179
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91299
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
CCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09899
TC106	DepMap CRISPR Gene Dependency	1.0	2.6277
Delta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.017
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
remission	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921145
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33319
oxalate	GeneRIF Biological Term Annotations	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.26001
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.21534
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10433
PMC3348545-NIHMS263168-supplement-3.pdf-279-ZNF518A_ZNF518A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3348
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32209
aldehyde catabolic process	GO Biological Process Annotations 2025	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970144
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	1.5645
Microbody lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
Dravet syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9081
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51692
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73062
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6006
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183271_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.846712
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82745
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKES1_BONE	CCLE Cell Line Proteomics	1.0	5.58354
oxo-acid-lyase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854441
Uric acid nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
monocarboxylic acid metabolic process	GO Biological Process Annotations 2023	1.0	null
BYSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
CTCF	ChEA Transcription Factor Targets	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC16A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66662
organic acid catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88299
NB10	DepMap CRISPR Gene Dependency	1.0	4.89562
GSE111247_0_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6119
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975142
GSE174735_2_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR3C1	ChEA Transcription Factor Targets	1.0	null
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62471
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	2.27647
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03953
DLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67487
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35044
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923221
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69029
Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
Larval integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.26655
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
vesicle	GO Cellular Component Annotations 2015	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11489
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10047
RecFOR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
OUMS23	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20121
utilizes	GeneRIF Biological Term Annotations	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU7-1426-SM-4BRWT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871025
GSE162276_2_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76573
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76524
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15655
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16415
Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE216538_5_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32757
inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.312827
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CNTNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44786
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11964
disease	GWASdb SNP-Disease Associations	1.0	0.033927
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-THRB_THRB	Rummagene Transcription Factor Associations 2026	1.0	null
PWWP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86007
Edema	CTD Gene-Disease Associations	1.0	1.11606
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05397
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03366
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833273
ZFAND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37564
GTEX-RWSA-1326-SM-47JX9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837715
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
CMAH_KO_GDS4200_114_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0596
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38498
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06139
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80699
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.8906
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8398-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77075
Perturb_5925_KD_LOXL1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.6957
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93552
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87404
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	2.05115
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-597	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
mitochondrial matrix	GO Cellular Component Annotations 2025	1.0	null
KARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88446
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15194
ESCRT II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.602
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929112
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14796
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.35386
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02293
GGCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84393
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29802
primary	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.04794
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46282
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36185
PMC12119775-13402_2024_1033_MOESM1_ESM.pdf-30-HNF1A_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01412
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.26001
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91973
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-143	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
intermediate stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22842
UOK101	CCLE Cell Line Gene Expression Profiles	1.0	1.85143
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cause	GeneRIF Biological Term Annotations	1.0	null
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06068
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96207
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23542
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041744
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50475
superior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868325
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dysuria	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894422
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1667
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923221
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995436
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5358
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56258
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46088
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
organonitrogen compound catabolic process	GO Biological Process Annotations 2015	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.25986
organonitrogen compound catabolic process	GO Biological Process Annotations 2023	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24187
RMGI	CCLE Cell Line Gene Expression Profiles	1.0	1.42507
ANKS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07684
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05506
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35105
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892748
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1326-SM-2XCDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846501
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91299
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33475
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1152
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059805
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pyruvic acid	HMDB Metabolites of Enzymes	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00509
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	3.36351
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13795
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94135
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845354
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12062_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Metabolite levels	GWAS Catalog SNP-Phenotype Associations	1.0	0.713153
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A66F-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940481
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-11A-12R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854881
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7735
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28162
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10285
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907787
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13448
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879782
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23808
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23643
Nephrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51695
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29047
FU97	DepMap CRISPR Gene Dependency	1.0	2.34619
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922364
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02212
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00573
GTEX-RTLS-2626-SM-46MUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855486
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15547
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
CORL47	DepMap CRISPR Gene Dependency	1.0	3.52997
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.62653
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836302
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04861
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
monocarboxylic acid catabolic process	GO Biological Process Annotations 2015	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
HUH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.983
liver	GTEx Tissue Gene Expression Profiles	1.0	1.1758
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05232
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2461
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056365
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04041
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24217
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-3609	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49899
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21687
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905867
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH28	CCLE Cell Line Gene Expression Profiles	1.0	1.52969
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9898
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06077
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5984_KD_YLPM1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.49511
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_17429_KO_Rbpj_SRP110038	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.51366
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00565
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16173
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048971
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7583-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868877
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8354
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.46629
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30515
Perturb_283_KD_BRD9_SRP303690	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03634
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880149
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70863
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05514
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51464
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958563
Nephrocalcinosis	DisGeNET Gene-Disease Associations	1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09579
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33228
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61242
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900659
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41099
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5898
Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.888
Pod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06627
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35596
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6845-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCIMY7	DepMap CRISPR Gene Dependency	1.0	3.21708
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KB-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03256
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XKR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22976
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10384
pyruvate biosynthetic process	GO Biological Process Annotations 2015	1.0	null
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20345
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15428
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883549
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVKATE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45914
PEA1	DepMap CRISPR Gene Dependency	1.0	6.03275
PBX3	ENCODE Transcription Factor Targets	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02472
IRAK4_Deficiency_GDS2641_653_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Developmental and epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
GATA2	ENCODE Transcription Factor Targets	1.0	null
pancreas	HPA Tissue Protein Expression Profiles	1.0	0.961041
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08662
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852926
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79896
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13633
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.965499
OCILY10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78112
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944589
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02172
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29831
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32209
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51692
oxo-acid-lyase activity	GO Molecular Function Annotations 2015	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.12634
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13068
Adenine phosphoribosyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.548
PMC11948025-ADVS-12-2416484-s001.pdf-118-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00401
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054772
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43691
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12997
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2056
Eye-limbal stem cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.122666
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81949
abnormality of urine homeostasis	HPO Gene-Disease Associations	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-802	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42225
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051342
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
T24_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	5.17071
PE/CA-PJ15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3785
mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.169859
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01269
hsa-miR-4733-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
NOZ	DepMap CRISPR Gene Dependency	1.0	2.59291
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.808
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892578
GTEX-XXEK-0526-SM-4BRWD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901025
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60935
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.39155
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22741
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.854
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.204
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36079
alpha-amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964996
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.229
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01745
STAT3	ENCODE Transcription Factor Targets	1.0	null
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45819
ACTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
Lung squamous cell carcinoma_LUSC_TCGA-66-2791-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1437_LUNG	CCLE Cell Line Proteomics	1.0	2.65389
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatocyte_Embryo_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITK_knockout_242_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44801
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19055
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848512
hsa-miR-328	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1355_LUNG	CCLE Cell Line Proteomics	1.0	4.93055
Lung squamous cell carcinoma_LUSC_TCGA-18-4086-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40803
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926694
cellular amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24109
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50366
4-hydroxyproline metabolic process	GO Biological Process Annotations 2025	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mitochondrial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.218914
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5U8-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78411
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2724
4-hydroxy-2-oxoglutarate aldolase activity	GO Molecular Function Annotations 2015	1.0	null
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41631
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7347
Perturb_2821_KD_Src_SRP194728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.58186
Bartter disease type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43416
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04916
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58431
Perturb_14310_KD_CD83_SRP178846	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928235
Adenoma_Adrenal gland_GSE8514	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.1385
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
BT20	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20013
alpha-amino acid catabolic process	GO Biological Process Annotations 2023	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4098
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14664
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51622
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
ADA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17162
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4693-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT55_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.05702
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
resolution	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834831
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14787
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27743
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	3.61507
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84237
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.539667
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38072
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.6708
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23757
SCC4	DepMap CRISPR Gene Dependency	1.0	2.46466
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47141
SP1	ENCODE Transcription Factor Targets	1.0	null
TIMM10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22142
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12898
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
organic cyclic compound catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urinary bladder	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41184
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92715
Hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21889
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23023
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
monocarboxylic acid catabolic process	GO Biological Process Annotations 2025	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30295
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.831812
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17687
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12755
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7082-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07012
NCIH1755	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61206
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.26
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857299
DapA-like	InterPro Predicted Protein Domain Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-acetylneuraminate catabolic process	GO Biological Process Annotations 2023	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.70989
cas1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1668
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20105
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55069
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
Bladder	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25182
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
maturity-onset diabetes of the young type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
PRKRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04659
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.185
Hydronephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
PMC8452540-mmc2.xlsx-Table_S3-Table_S3_Differentially_expressed_genes_resulting_from_pairwise_comparisons_of_samples_derived_from_cells_with_different_HNF1B_genotypes_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36864
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41082
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10339
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840632
GSE216538_0_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9513
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67403
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1593
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29339
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_32_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
496100517_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02086
Primary hyperoxaluria, type III	ClinVar Gene-Phenotype Associations	1.0	null
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.299
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC3708595-NIHMS474972-supplement-1.pdf-6-FOXO3_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51758
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06311
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96228
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10504
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957905
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94867
USF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11244912-media-3.xlsx-Sheet2-ESR1_mutation_de_novo_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.25911
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883899
detection	GeneRIF Biological Term Annotations	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60932
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056331
hydroxyproline	GeneRIF Biological Term Annotations	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A77X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041285
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52137
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24847
CTCF-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5989_KD_ZNF207_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GATA3-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26098
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69029
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4887-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.128
maturity-onset diabetes of the young	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.501144
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14575
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892819
PMC8253910__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Peroxisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.196
HT1197	DepMap CRISPR Gene Dependency	1.0	8.37782
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62624
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EK-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1593
ATP2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5378
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59587
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48015
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4517
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59013
GSE62843,GSE64370_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04143
ONECUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72609
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A560-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48968
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.02447
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991089
Metabolism	Reactome Pathways 2024	1.0	null
Phosphoribosylpyrophosphate synthetase superactivity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05481
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31499
GSE178267_2_v_4_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Ureter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.437
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4G_HNF4G	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8097
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049035
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86664
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1028
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.865127
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62848
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85079
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10417
residue	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08244
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01547
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.21181
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930921
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.333
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56168
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940454
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11408
intermediate stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2271
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88533
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amino sugar catabolic process	GO Biological Process Annotations 2023	1.0	null
NCIH1092	DepMap CRISPR Gene Dependency	1.0	2.78849
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04995
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45501
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal liver physiology	MGI Mouse Phenotype Associations 2023	1.0	null
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33367
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GE-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65493
WM1799	DepMap CRISPR Gene Dependency	1.0	2.25619
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97577
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39981
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08096
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994885
HCC56	DepMap CRISPR Gene Dependency	1.0	3.30556
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998426
SCC-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Glyoxylic acid	HMDB Metabolites of Enzymes	1.0	null
carboxylic acid catabolic process	GO Biological Process Annotations 2023	1.0	null
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4328
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867259
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835788
MET_knockout_247_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73675
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40787
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
APPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1673
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17005
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.779
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52956
ZSCAN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43576
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95236
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
4-hydroxy-2-oxoglutarate aldolase activity	GO Molecular Function Annotations 2023	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	1.55416
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863439
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16154
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6012-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919347
ZKSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10453
hsa-miR-4448	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827962
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22177
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24017
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01197
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WAOSEL	DepMap CRISPR Gene Dependency	1.0	2.81467
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36107
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-11A-12R-A26B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38386
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73595
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39548
LPS6	DepMap CRISPR Gene Dependency	1.0	4.02468
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2657
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53418
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03591
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07936
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83704
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38877
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11637
Primary hyperoxaluria type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.012
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63371
mitochondrial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.189857
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04619
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.00942
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43862
SUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50538
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00968
MLST8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88516
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.47851
KASUMI6	CCLE Cell Line Gene CNV Profiles	1.0	1.36351
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12061_KO_Stat5a_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55406
STK40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9586
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47097
HNF4A	ChEA Transcription Factor Targets	1.0	null
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98778
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.25121
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4601-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP1LC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4279
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926263
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21993
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44506
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836293
protein dimerization activity	GO Molecular Function Annotations 2015	1.0	null
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069715
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6137
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48777
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.904
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6006
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09472
liver	HPA Tissue Gene Expression Profiles	1.0	1.02209
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	1.4912
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.10434
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57415
GOLM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77901
Urolithiasis	HuGE Navigator Gene-Phenotype Associations	1.0	null
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.77847
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14195
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.95145
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34859
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02966
GTEX-SNOS-0726-SM-4DM5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02435
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36276
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19279
NCI-H2030	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990132
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
obesity	GWASdb SNP-Phenotype Associations	1.0	0.454047
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48312
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0704
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09573
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_278_KD_ZHX2_SRP343502	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08096
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.199
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12608
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86428
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.15661
modified amino acid catabolic process	GO Biological Process Annotations 2025	1.0	null
SNU398	CCLE Cell Line Gene CNV Profiles	1.0	1.45716
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76378
MYCN	ChEA Transcription Factor Targets	1.0	null
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4219
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.957428
OCIM2	DepMap CRISPR Gene Dependency	1.0	4.08908
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903754
Lung adenocarcinoma_LUAD_TCGA-95-8039-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930734
aldehyde catabolic process	GO Biological Process Annotations 2015	1.0	null
TFPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3403
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34936
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041804
decreased thigmotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.45299
CAKI2	CCLE Cell Line Gene Expression Profiles	1.0	1.38169
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3W-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11408861-mmc2.pdf-4-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01293
submandibular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.818994
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05161
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41516
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11835
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27396
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.01966
GTEX-SNOS-0826-SM-4DM5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890445
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08629
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0366
ZNF568	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46464
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966286
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08035
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.465282
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
N-acetylneuraminate lyase activity	GO Molecular Function Annotations 2023	1.0	null
GTF2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99284
PMC8949908__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_5982_KD_YBX1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.67973
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14515
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer II of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845512
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052344
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2236
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36444
hsa-miR-92a-3p	MiRTarBase microRNA Targets	1.0	null
GSE89032,GSE89033_0_v_1_sfpq_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31907
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28215
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38595
HNF4A_KD_GSE29084_694_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831384
GSE147876,GSE147877_4_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
SLR26	CCLE Cell Line Gene Expression Profiles	1.0	1.77958
Perturb_11111_KO_Tsc1/Cpt2_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
IGR39	DepMap CRISPR Gene Dependency	1.0	2.06631
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.69166
variants	GeneRIF Biological Term Annotations	1.0	null
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular modified amino acid catabolic process	GO Biological Process Annotations 2023	1.0	null
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5004
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920771
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31004
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4P0-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8T8-1226-SM-4E3IH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17336
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
REXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36619
aldehyde-lyase activity	GO Molecular Function Annotations 2015	1.0	null
Urethra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Lung squamous cell carcinoma_LUSC_TCGA-85-8277-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01384
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3451
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51565
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905438
biochemical	GeneRIF Biological Term Annotations	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848688
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15644
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57245
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30734
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05041
Schiff base-forming aldolase, active site	InterPro Predicted Protein Domain Annotations	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Nauplius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
MAX	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EG-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976217
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.98236
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4027
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39123
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08904
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85705
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19991
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24865
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27913
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09129
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4323	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13842
RDES	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62501
Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24028
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr10_97609256_C_A_b38	GTEx eQTL 2025	1.0	2.51051
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.85387
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.42293
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49395
Lung squamous cell carcinoma_LUSC_TCGA-34-5240-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46786
Primary Hyperoxaluria Type Iii	DisGeNET Gene-Disease Associations	1.0	null
approximately	GeneRIF Biological Term Annotations	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39637
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834205
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Glyoxysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.7
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11183
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.05809
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.377325
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73614
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17633
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23778
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76364
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
KIJK	DepMap CRISPR Gene Dependency	1.0	2.18159
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0975
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52193
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
small molecule catabolic process	GO Biological Process Annotations 2015	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14858
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43511
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831747
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77141
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28511
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Nmyc_OE_GDS2406_14_mouse_LUNG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053311
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cellular modified amino acid catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.17593
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.35982
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.85212
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pyruvate biosynthetic process	GO Biological Process Annotations 2025	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4486	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
calcium nephrolithiasis	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53894
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07837
Perturb_285_KD_GPD1L_SRP303690	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Xanthinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.896
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18697
obesity	GWASdb SNP-Disease Associations	1.0	0.532281
Acquired Immunodeficiency Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.9225
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04179
WDR44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62421
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982756
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cSARS Bat SRBD_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.2276
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88964
Anteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0494
PMC11694450-Table_1.xlsx-MR_to_MM_at_2_DPI-Supplementary_Table_1_1_Differentially_expressed_genes_in_the_cecal_tonsil_transcriptome_in_the_M_R_group_compared_to_the_M_M_group_at_2_DPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853602
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18119
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.889027
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14252
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89371
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bacteriocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
EBF1	ENCODE Transcription Factor Targets	1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23012
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0966
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3667
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76014
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25622
Increased Frequency Of Micturition	DisGeNET Gene-Phenotype Associations	1.0	null
decreased thigmotaxis	IMPC Knockout Mouse Phenotypes	1.0	null
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21504
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18157
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.272
GSE237040_0_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36688
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26312
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
carboxylic acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary hyperoxaluria	ClinVar Gene-Phenotype Associations 2025	1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17975
hsa-miR-1268	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01719
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2536
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40152
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26814
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978122
diffracted	GeneRIF Biological Term Annotations	1.0	null
bladder	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14179
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43168
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05586
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64878
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934901
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.096388
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10099
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845378
Acute Myeloid Leukemia_LAML_TCGA-AB-2854-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serum Albumin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab10_KDM5C-KD-up-DKD-rescued-Table_10_Up-regulated_genes_in_KDM5C-KD_and_rescued_genes_in_DKD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4167
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YO-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09878
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37146
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862208
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46277
TBP	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01461
hsa-miR-1254	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53259
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10373
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8150-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08651
HYPEROXALURIA, PRIMARY, TYPE III	CTD Gene-Disease Associations	1.0	2.88009
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12259
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18855
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34752
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835547
incomplete	GeneRIF Biological Term Annotations	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44559
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61955
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84531
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14909
YPEL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24948
MM1S	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06299
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22282
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67782
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14515
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A60K-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18295
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08288
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14467
iii	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958158
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.696
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07713
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16878
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4527
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12856
4-hydroxyproline metabolic process	GO Biological Process Annotations 2023	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97089
Oculocerebrorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70147
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40591
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10526
NCIH524	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74476
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58645
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48661
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51489
Nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.136
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5857
GSE237812,GSE237813_3_v_2_hmgb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50186
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.03411
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95285
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.436
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6319725-pone.0204197.s006.xlsx-Table_S2-S2_TABLE_-_Operon_Expression_and_SOM_clustering_data_for_Gene_Set_identified_by_ANOVA_p_0_005_1005_genes_FDR_8_8_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33741
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043854
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Glyoxylate metabolism	WikiPathways Pathways 2024	1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X62O-0826-SM-46MW8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22744
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
xrays	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H6PD_KO_GDS3195_603_mouse_Skeletal muscle - Tibialis anterior	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14268
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13328_KD_Mnt_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.38696
carbon-carbon lyase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01371
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48765
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
RCC10RGB	CCLE Cell Line Gene Expression Profiles	1.0	1.55021
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70963
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954957
ZNF582	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21684
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890383
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00563
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928085
Primary hypomagnesemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903036
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00877
calcium	GeneRIF Biological Term Annotations	1.0	null
WDR76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56202
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91299
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92294
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52537
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21621
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
organonitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00262
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2918
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40648
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28239
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968611
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933361
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31636
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
ESO51	DepMap CRISPR Gene Dependency	1.0	2.01359
hsa-miR-548ah	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910278
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Short bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91947
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22645
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852906
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32462
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.086
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-515-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889532
urinary bladder	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21721
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
253J	CCLE Cell Line Gene Expression Profiles	1.0	1.66966
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910089
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.268884
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.726
step	GeneRIF Biological Term Annotations	1.0	null
greater	GeneRIF Biological Term Annotations	1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868645
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4474-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889532
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30105
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
metabolism	GAD Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963297
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47489
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04713
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
foreign-body giant cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85841
cyclophosphamide_rattus norvegicus_gpl1355_gse48407	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034194
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55098
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09097
Glycolate oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.441
SUDHL10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69376
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7132
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30666
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3934	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Brain Lower Grade Glioma_LGG_TCGA-CS-6667-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE160373_8_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Scrapie	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42238
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897717
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8383
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051193
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5291
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09943
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971404
type	GeneRIF Biological Term Annotations	1.0	null
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33268
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
obtained	GeneRIF Biological Term Annotations	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09609
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44331
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5358
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09972
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19215
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59083
SMC3	ENCODE Transcription Factor Targets	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01599
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57379
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.37234
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12438
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74915
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.01698
interactions	GeneRIF Biological Term Annotations	1.0	null
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66204
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02484
aa94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02821
4-hydroxyproline degradation	HumanCyc Pathways	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45781
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848275
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77914
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0391
8-MG-BA	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.09365
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
despite	GeneRIF Biological Term Annotations	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6184
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0926-SM-4DXU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861571
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.92514
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.45626
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCC-JW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868877
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.212627
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87114
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13189
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16206
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.15458
monocarboxylic acid biosynthetic process	GO Biological Process Annotations 2023	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76185
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66962
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57239
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.391141
t24/83	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37002
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.67998
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938488
GRM	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00537
Weight Loss	CTD Gene-Disease Associations	1.0	1.13075
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16923
LMX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52934
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912129
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53358
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0175
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12997
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLP8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76789
Glyoxylate metabolism and glycine degradation	Reactome Pathways 2024	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1223
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76581
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Root apex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.28201
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885703
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17129
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44477
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	2.07457
TUHR14TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.46308
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35916
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
HMGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15637
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44909
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09952
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22886
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0572
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887938
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25942
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32094
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80869
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24271
organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28482
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63588
glyoxylate catabolic process	GO Biological Process Annotations 2023	1.0	null
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933108
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	2.97499
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.97579
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF4alpha_DEPLETION_GDS4798_91_human_HepG2 hepatocellular carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.218563
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	3.41104
TBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97618
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17732
hsa-miR-550a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73082
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33869
BL2777 (NF2)	NURSA Protein Complexes	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	1.47233
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88457
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921453
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91063
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31356
GSE211357_1_v_0_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	5.14835
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07334
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.912835
hsa-miR-4708-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978755
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4959-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oxo-acid-lyase activity	GO Molecular Function Annotations 2023	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16519
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42432
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Methane monooxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.565
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87023
decreased anxiety-related response	IMPC Knockout Mouse Phenotypes	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892283
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.81639
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1357
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4353_KO_Pten_SRP260985	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8831
HS578T	DepMap CRISPR Gene Dependency	1.0	2.19003
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMG-I	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.1212
Perturb_5937_KD_NCOA5_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.6748
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.164
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
A704	CCLE Cell Line Gene Expression Profiles	1.0	2.58116
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829054
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882476
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.26001
HGC27	DepMap CRISPR Gene Dependency	1.0	2.46752
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42927
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
pyruvate metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46136
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.885
D-glyceric aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43X-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9669
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5634
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.26001
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.163
hsa-miR-519e	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5911_KD_GATAD2B_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.02592
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.75641
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	2.06759
HS840T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.51664
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
cellular modified amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19853
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44711
phenylalanine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
Perturb_5988_KD_ZNF207_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02227
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49014
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40722
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868877
KASUMI1	CCLE Cell Line Gene CNV Profiles	1.0	1.48086
JSC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.85585
PMC12484354-40620_2025_2355_MOESM1_ESM.docx-0-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91299
Lung adenocarcinoma_LUAD_TCGA-86-8669-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.332967
condition	GeneRIF Biological Term Annotations	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21967
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57636
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1979
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.323
hsa-miR-4763-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6409
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4321
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39132
MDAMB468_BREAST	CCLE Cell Line Proteomics	1.0	3.22487
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56042
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825211
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22694
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
monocarboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922572
PURG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23183
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0343
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.17593
Bartter disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988312
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19467
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11818
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
CLASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81809
PMC11711664-41598_2025_85366_MOESM6_ESM.xlsx-AA-METABOLIC_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15328
IOSE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93358
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4741	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13044
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKRD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52542
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8652378__F1	PFOCR Pathway Figure Associations 2024	1.0	null
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0672
genetic	GeneRIF Biological Term Annotations	1.0	null
GSE62843,GSE64370_4_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496483
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78691
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056537
SNU601	DepMap CRISPR Gene Dependency	1.0	2.99421
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.839
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
hyperoxaluria	GeneRIF Biological Term Annotations	1.0	null
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.30287
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12695
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00603
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
glyoxylate metabolic process	GO Biological Process Annotations 2025	1.0	null
organic aciduria	HPO Gene-Disease Associations	1.0	null
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE168797_2_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.25614
an3ca	HPA Cell Line Gene Expression Profiles	1.0	0.884194
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45009
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21612
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02191
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.955319
intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067732
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.59241
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00383
reaction	GeneRIF Biological Term Annotations	1.0	null
Renal glycosuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.00424
ATOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06025
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05324
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52206
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
DANG_PANCREAS	CCLE Cell Line Proteomics	1.0	2.34526
GSE143944_1_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1326-SM-4LVMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15557
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCDC90B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77832
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74165
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81831
Mesothelioma_MESO_TCGA-SC-A6LQ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85079
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03501
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42166
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23991
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49234
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84992
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26986
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14206
liver_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.09338
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
protein homodimerization activity	GO Molecular Function Annotations 2025	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.26001
alpha-amino acid catabolic process	GO Biological Process Annotations 2025	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11948025-ADVS-12-2416484-s001.pdf-118-ENSG00000136574_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.66544
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-proteinogenic amino acid catabolic process	GO Biological Process Annotations 2025	1.0	null
GSE242199_2_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Renal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
Hydathode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.880956
GT1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
small molecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03162
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62967
GSE126762_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08907
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89043
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86726
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6073
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12119775-13402_2024_1033_MOESM1_ESM.pdf-30-ENSG00000135100_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23063
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.908933
catalyzing	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11927
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1939
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60668
stomach_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
Spondylometaphyseal dysplasia with cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65043
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nephronophthisis 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84584
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02613
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840154
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11955
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53737
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05364
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85829
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.496271
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19284
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Table_S5A_Upregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03183
GSE206516,GSE206518_5_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	2.39367
seven	GeneRIF Biological Term Annotations	1.0	null
carboxylic acid catabolic process	GO Biological Process Annotations 2015	1.0	null
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837407
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70608
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Hemorrhage	CTD Gene-Disease Associations	1.0	1.15156
TCF12	ENCODE Transcription Factor Targets	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4575
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11817
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
4-hydroxyproline catabolic process	GO Biological Process Annotations 2025	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849189
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
hsa-miR-1972	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06892
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08267
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
hsa-miR-3116	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26476
idiopathic	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32014
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4688
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42165
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83031
TIS granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Metabolism of amino acids and derivatives	Reactome Pathways 2024	1.0	null
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53193
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46765
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2004
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.85044
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cc81	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90376
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068839
GSE166317_3_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861706
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0125
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00107
E2F6	ENCODE Transcription Factor Targets	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2818
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.76864
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31004
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62152
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21185
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220378
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37003
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9201
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876164
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34631
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05729
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22212
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosome Aberrations	CTD Gene-Disease Associations	1.0	1.17268
SW48	DepMap CRISPR Gene Dependency	1.0	2.092
RCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20589
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.937893
Phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
hsa-miR-4430	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
Inflammatory bowel disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
EBC1	DepMap CRISPR Gene Dependency	1.0	2.10776
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6797
hsa-miR-4437	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18499
hepg2	HPA Cell Line Gene Expression Profiles	1.0	1.28313
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36824
Lung adenocarcinoma_LUAD_TCGA-69-7760-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1973	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14215
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04861
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874596
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3WB-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.961
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10575
hsa-miR-4284	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68122
NF-Y	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BAZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41168
Inflammatory bowel disease 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.82116
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35077
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
pyruvate biosynthetic process	GO Biological Process Annotations 2023	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852436
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.299092
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NRK-52E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64911
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71543
abnormal behavior	IMPC Knockout Mouse Phenotypes	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13713
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06665
VMRCRCZ	CCLE Cell Line Gene Expression Profiles	1.0	2.00376
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34979
PMC12141477-41467_2025_60329_MOESM3_ESM.xlsx-log2FC_0_5_cut_off_-_258_genes-Supplementary_Data_1_Genes_identified_by_both_HLF_overexpression_OE_and_knockout_KO_RNAseq_HLF	Rummagene Transcription Factor Associations 2026	1.0	null
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09124
Tubulointerstitium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27618
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9611
urolithiasis	GeneRIF Biological Term Annotations	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
testis	HPA Tissue Protein Expression Profiles	1.0	1.82116
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03142
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08096
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lesch-Nyhan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11901
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44362
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.21573
Pyuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895331
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77247
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32542
GSE193027_1_v_0_krt19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872471
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5316
PMC8253910-mmc9.xlsx-Sheet1-Supplemental_Table_9_ARCHS4_analysis-_z_scores_of_PPAR-family_transcription_factors_in_genes_encoding_DE_Proteins_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051341
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37424
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
TFAP2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02869
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1972
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61451
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pyruvate metabolic process	GO Biological Process Annotations 2025	1.0	null
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7485
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aldolase	GeneRIF Biological Term Annotations	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.47977
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53775
Perturb_12064_KO_Stat5a/Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836869
PRDM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51693
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044389
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.68996
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52986
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.05656
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05335
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67245
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08788
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16002
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34253
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3043
hsa-miR-4308	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Acute Myeloid Leukemia_LAML_TCGA-AB-2869-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7J9-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836141
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11918
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923221
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5319-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1272	CCLE Cell Line Gene Expression Profiles	1.0	1.8774
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946546
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Hereditary hypophosphatemic rickets with hypercalciuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06631
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
hnf4a_16714383_e18dot5_liver_lof_mouse_gpl1261_gds1916	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.365223
CCLP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
hsa-miR-4533	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.594451
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57453
PMC11601903-jciinsight-9-175998-s107.pdf-4-GCM2_GCM2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
forms	GeneRIF Biological Term Annotations	1.0	null
Nephrolithiasis	DisGeNET Gene-Disease Associations	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.07625
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47487
TC71_BONE	CCLE Cell Line Proteomics	1.0	3.22533
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2052	DepMap CRISPR Gene Dependency	1.0	3.88104
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09972
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848707
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00979
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18505
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55346
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01164
Chronic wasting disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1916
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54912
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866852
KLF5_KO_GDS3509_553_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
USF2_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30069
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MP-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
KARPAS422	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60141
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.838319
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47068
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56839
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835941
Fat-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.122666
hsa-miR-4254	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42023
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833732
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1701
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.02114
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15464
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96942
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53979
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93575
MONO-MAC-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01802
NB6	DepMap CRISPR Gene Dependency	1.0	5.3559
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29464
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84051
favorable	GeneRIF Biological Term Annotations	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13583
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08488
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04816
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33306
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.405305
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23485
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0406
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4634
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18623
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05358
efo21	HPA Cell Line Gene Expression Profiles	1.0	1.13033
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ureteropelvic junction obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3778
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90425
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.254
strongly	GeneRIF Biological Term Annotations	1.0	null
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2458
RAD51B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82938
RS5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58415
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979233
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8979
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994957
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07281
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25972
GSE162276_2_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48332
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.14064
GSE206516,GSE206518_0_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
mantle zone of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21313
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55197
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34581
predisposing	GeneRIF Biological Term Annotations	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1689
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-ESR1_mutation_de_novo_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9033
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355942
dicarboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DMRT1	ChEA Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09223
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98469
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29088
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0001
Brain Lower Grade Glioma_LGG_TCGA-TM-A84S-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827126
pyruvate metabolic process	GO Biological Process Annotations 2023	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18565
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40519
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59408
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH647_LUNG	CCLE Cell Line Proteomics	1.0	2.22244
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969864
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36188
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.73677
HEY	DepMap CRISPR Gene Dependency	1.0	3.66341
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1529
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5880-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aldehyde catabolic process	GO Biological Process Annotations 2023	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4661-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069838
HUH1	DepMap CRISPR Gene Dependency	1.0	2.79165
point	GeneRIF Biological Term Annotations	1.0	null
Perturb_12141_KO_Lgals9_ERP122370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.02463
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14123
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32956
mitochondrial chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.219265
ventral pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18234
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0266
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17554
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00699
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.555
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842119
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84243
Perturb_18229_KO_Insr/Igf1r_SRP190169	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.94372
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49213
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05616
Perturb_8423_KO_DGAT2_ERP114849	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951851
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44896
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76316
MM370	DepMap CRISPR Gene Dependency	1.0	2.88886
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0682
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R2-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26584
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874596
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52066
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
RABAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97658
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.991115
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47866
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41682
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44058
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24558
Lung squamous cell carcinoma_LUSC_TCGA-56-A5DS-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7813
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48736
Primary Hyperoxaluria	DisGeNET Gene-Disease Associations	1.0	null
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05115
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A3LQ-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10260405-41588_2023_1409_MOESM6_ESM.xlsx-ST12-Supplementary_Table_12_Most_likely_causal_genes_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44323
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45179
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.852184
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32294
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95621
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43971
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97061
intracellular organelle lumen	GO Cellular Component Annotations 2023	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56897
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883886
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00829
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism catabolic process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-6867-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974048
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88386
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0019
MCAS	CCLE Cell Line Gene CNV Profiles	1.0	1.81002
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
Atrophy	CTD Gene-Disease Associations	1.0	1.13793
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38898
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44717
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874577
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAA50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28522
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5897_KD_CCDC86_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.59297
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC9884267-41467_2023_36114_MOESM4_ESM.xlsx-dereg_genes_upon_HMG20A_siRNA_p-Unnamed_0_HMG20A	Rummagene Transcription Factor Associations 2026	1.0	null
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97546
hsa-miR-616	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
decreased anxiety-related response	MGI Mouse Phenotype Associations 2023	1.0	null
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
SW1710	CCLE Cell Line Gene Expression Profiles	1.0	1.49151
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0211
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66257
P2RX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83389
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2266
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46585
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923221
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47941
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.110737
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04861
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nephrolithiasis	HPO Gene-Disease Associations	1.0	null
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51508
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.639
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45042
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869688
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
USP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10942
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6023-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15309
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73504
T47D	CCLE Cell Line Gene CNV Profiles	1.0	1.48663
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04843
SCARA5_Down Expression_GSE32323_611_human_Colorectal Cancer Cell lines	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RAD21	ENCODE Transcription Factor Targets	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86784
CTCF_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81897
CESS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962535
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51262
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21112
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13206
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary hyperoxaluria type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.851
mitochondrial matrix	GO Cellular Component Annotations 2023	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04861
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826211
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64619
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9081
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03946
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01547
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81642
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62095
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RCM1	DepMap CRISPR Gene Dependency	1.0	2.30024
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dicarboxylic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00529
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89782
Urethral calculus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08391
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05334
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996886
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884046
overnutrition	GWASdb SNP-Disease Associations	1.0	0.404368
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.35972
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02971
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21296
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052714
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69155
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48913
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1729
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60258
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65804
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10433
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7567
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.66755
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	2.29661
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74308
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23528
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7035
RK-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UOK101	CCLE Cell Line Gene CNV Profiles	1.0	1.50658
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37172
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58838
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4ZB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212486,GSE212488_2_v_3_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905784
abnormal blood homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74168
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
Cisplatin	CTD Gene-Chemical Interactions	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AA-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11661
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01435
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.58598
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051321
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994559
monocarboxylic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-4675	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18719
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047724
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75357
RBM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13612
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19498
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25239
Lateral terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22021
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74753
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rhizomelic chondrodysplasia punctata type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3673	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998819
TOV21G	CCLE Cell Line Gene CNV Profiles	1.0	1.70049
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.35769
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857774
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62732
lyase activity	GO Molecular Function Annotations 2015	1.0	null
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40222
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66039
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.58255
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glyoxylate catabolic process	GO Biological Process Annotations 2025	1.0	null
ESO26	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.01469
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84985
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7817
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8489
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21664
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
16498405-TableS4	GeneSigDB Published Gene Signatures	1.0	null
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07804
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06966
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03721
Perturb_6669_KO_FGFR3/FGFR4_SRP386785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.52613
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.365
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53003
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0173
PMC5259899-13287_2016_455_MOESM2_ESM.xlsx-Up-regulated-Supplementary_Table_S2_Up-reguated_genes_expression_in_MESP1_positive_cells_MESP1	Rummagene Transcription Factor Associations 2026	1.0	null
SKNSH	DepMap CRISPR Gene Dependency	1.0	2.42952
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16732
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
ZNF789	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11576
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS618T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73946
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931374
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormal urine homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.304864
FOXA2	ENCODE Transcription Factor Targets	1.0	null
purine-pyrimidine metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.149
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MF-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20398
inferior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.934333
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23288
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49213
MITF	ChEA Transcription Factor Targets	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12161
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2446
ASIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0026
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927173
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rhizomelic chondrodysplasia punctata type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15766
SKMEL28_SKIN	CCLE Cell Line Proteomics	1.0	2.65934
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33596
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44884
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14649
furan	CTD Gene-Chemical Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3001-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911613
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66075
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72261
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE149075_6_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14384
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903927
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954974
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058298
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903824
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868877
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	3.50594
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193334_1_v_0_six1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96851
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922447
769P	CCLE Cell Line Gene Expression Profiles	1.0	1.41475
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16486
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09777
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	2.33905
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
encoding	GeneRIF Biological Term Annotations	1.0	null
Perturb_5928_KD_MATR3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.65381
aldehyde-lyase activity	GO Molecular Function Annotations 2023	1.0	null
increased body weight	GWASdb SNP-Phenotype Associations	1.0	0.454047
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92295
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26037
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47895
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915561
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52798
different	GeneRIF Biological Term Annotations	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844407
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14058
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63105
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12171
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
heterocycle catabolic process	GO Biological Process Annotations 2015	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46328
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883031
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993233
Cholestasis	DisGeNET Gene-Disease Associations	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50132
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05616
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7026
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5933_KD_MRTO4_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.48381
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	4.16361
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16982
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01969
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4674
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11247
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24838
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5158
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05497
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94657
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
major	GeneRIF Biological Term Annotations	1.0	null
X31(H3N2)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92381
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IQCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74574
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	1.69467
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918099
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96901
F11R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01889
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SQSTM1_OE_GDS2653_651_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03734
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17633
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
1min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.173
hsa-miR-4528	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10101
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18718
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8047
final	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3652	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE210718_1_v_0_shmt2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE249146_2_v_3_dusp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
TOV21G	CCLE Cell Line Gene Expression Profiles	1.0	1.60919
NFYB	ENCODE Transcription Factor Targets	1.0	null
Perturb_5922_KD_KHDRBS1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.03173
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50901
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.953268
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
appendices_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
4-Hydroxy-2-oxoglutaric acid	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13405
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18877
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	2.1697
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
X-linked recessive hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09137
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34264
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12799
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JM1	CCLE Cell Line Gene CNV Profiles	1.0	1.38836
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
Chronic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29253
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
rectum_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
Arginine and proline metabolism	KEGG Pathways 2026	1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0717
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2306
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832503
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892925
Hyperoxaluria, Primary	HuGE Navigator Gene-Phenotype Associations	1.0	null
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29295
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KIF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10352
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04134
glyoxylate metabolic process	GO Biological Process Annotations 2023	1.0	null
Thyroid primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.992734
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874261
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14199
WM3772F	DepMap CRISPR Gene Dependency	1.0	2.13755
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38514
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65668
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.973
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02021
GSE188599_1_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69455
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33211
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
LASV_FML29 _4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.13684
metabolic	GeneRIF Biological Term Annotations	1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54473
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955459
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883594
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15391
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74084
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alpha-CP1	MotifMap Predicted Transcription Factor Targets	1.0	null
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08832
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.42183
ChIP_CTCF_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.31659
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843733
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03295
Cytochrome o ubiquinol oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
Acute Myeloid Leukemia_LAML_TCGA-AB-2930-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.663
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14272
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
NZM42	DepMap CRISPR Gene Dependency	1.0	2.09247
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32873
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21084
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.238752
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27017
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10759
heart	GTEx Tissue Gene Expression Profiles	1.0	0.827254
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05256
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58758
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE222445_2_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1268b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MEC1	CCLE Cell Line Gene CNV Profiles	1.0	1.68014
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40217
USF1	ENCODE Transcription Factor Targets	1.0	null
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060641
hMPV_12Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.35321
GSE130401_6_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07077
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74809
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21416
Aldolase-type TIM barrel	InterPro Predicted Protein Domain Annotations	1.0	null
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68368
ERFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41828
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211357_2_v_0_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
suggests	GeneRIF Biological Term Annotations	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12015
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79454
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6478
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55671
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03276
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.90375
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51216
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41004
Hyperoxaluria	DisGeNET Gene-Disease Associations	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97577
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18831
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864779
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
metabolic process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-759	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93787
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928683
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
U178	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34246
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03519
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.12393
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.61309
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
crystal	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4354
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870886
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862484
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04305
14555994-Table2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18801
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944962
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28999
LOU-NH91	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08489
D502MG	DepMap CRISPR Gene Dependency	1.0	3.94909
DOV13	DepMap CRISPR Gene Dependency	1.0	2.05724
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-218-LCOR_LCOR	Rummagene Transcription Factor Associations 2026	1.0	null
20min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
basomedial nucleus (accessory basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847185
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3082
Primary somatosensory area, unassigned, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10146
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Metabolism	dbGAP Gene-Trait Associations	1.0	1.07287
TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.85706
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21503
Adrenocortical carcinoma_ACC_TCGA-OR-A5JS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8295
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.934405
Perturb_12065_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE14_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.18323
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03978
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S5-Supplemental_Table_S5_Genes_commonly_downregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.873861
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37509
TFAP2A	ENCODE Transcription Factor Targets	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843118
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.573
Uric acid urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.647
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE30	DepMap CRISPR Gene Dependency	1.0	2.25881
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05322
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61833
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964065
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041658
GSE134986_7_v_3_oma1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_3455_KO_Mecp2_SRP017936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.49263
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
4-hydroxyproline metabolic process	GO Biological Process Annotations 2015	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78026
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02338
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888102
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL54	CCLE Cell Line Gene Expression Profiles	1.0	1.63329
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29136
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2065
Perturb_10883_KO_Trp53_SRP322469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.22722
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2289
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91399
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77834
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53061
neuronal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.903701
GSE250534_0_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.53657
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0203_PANCREAS	CCLE Cell Line Proteomics	1.0	3.03531
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10791
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PL-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50198
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PELI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72413
cellular aldehyde metabolic process	GO Biological Process Annotations 2015	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053881
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKAP8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15527
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1285
Perturb_5945_KD_PPHLN1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.27917
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12387
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16647
heterogeneity	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE88819_5_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976217
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
nevoid basal cell carcinoma syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.86018
BHY	DepMap CRISPR Gene Dependency	1.0	4.43188
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.954355
glyoxylate catabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1789
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16411
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07769
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
glyoxylate metabolic process	GO Biological Process Annotations 2015	1.0	null
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
oxalate metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42147
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77149
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20759
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34827
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71173
KLF4	ChEA Transcription Factor Targets	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05212
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05707
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular amino acid catabolic process	GO Biological Process Annotations 2015	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.6652
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04689
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23158
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OE33	CCLE Cell Line Gene CNV Profiles	1.0	1.35572
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17626
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.967683
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46933
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05331
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.267
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23098
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852122
fungal-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18216
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.059709
TNKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53593
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19424
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058563
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30913
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05287
MBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90333
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.946528
Renal pyramid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890071
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5994
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1671
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.77847
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16996
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1271_LUNG	CCLE Cell Line Proteomics	1.0	5.88307
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12679
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00678
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.309037
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
MCAS	DepMap CRISPR Gene Dependency	1.0	3.19574
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59421
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.07641
Hematuria	DisGeNET Gene-Phenotype Associations	1.0	null
hyperactivity	IMPC Knockout Mouse Phenotypes	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Bacteriuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34788
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48524
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.849062
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02585
LRFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5112
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
LRRK2	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83009
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16157
Perturb_3805_KO_Cftr_SRP067491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.7748
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05687
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01757
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3069
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13366
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93
NR3C1	ENCODE Transcription Factor Targets	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1354
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.465282
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25963
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1835
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04243
RL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.34934
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF740	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27816
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53475
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36115
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.08942
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054635
KMRC20	CCLE Cell Line Gene Expression Profiles	1.0	1.64782
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate-sperm	Tabula Sapiens Gene-Cell Associations	1.0	-0.122666
Glyoxylate and dicarboxylate metabolism	KEGG Pathways 2026	1.0	null
IGROV1	CCLE Cell Line Gene CNV Profiles	1.0	2.42611
Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6875
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-651	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5896_KD_CCDC59_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.91858
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29464
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GU-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.12994
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6478
4-hydroxyproline catabolic process	GO Biological Process Annotations 2023	1.0	null
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
B4GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83391
TFEB	ChEA Transcription Factor Targets	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102870_1_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1057
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00442
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08161
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21631
Microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.196
GSE162739_2_v_1_bap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.978876
Perturb_5893_KD_CBX3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.3377
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78688
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218060_1_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
employs	GeneRIF Biological Term Annotations	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11918
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841575
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08262
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ML-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041276
intracellular organelle lumen	GO Cellular Component Annotations 2025	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929779
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03365
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-667-ENSG00000196233_LCOR	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.843653
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.225933
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868877
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5907
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959083
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EC-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976217
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1206
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78042
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45601
AMO1	DepMap CRISPR Gene Dependency	1.0	2.28838
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50097
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890383
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00841
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A4EM-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO27	DepMap CRISPR Gene Dependency	1.0	2.65749
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30069
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00192
Lower urinary tract calculus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11735
Dent disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.21
RVH421	DepMap CRISPR Gene Dependency	1.0	2.01854
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70202
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21831
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hyperoxaluria, primary, type iii	OMIM Gene-Disease Associations	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
RESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31753
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alpha-amino acid catabolic process	GO Biological Process Annotations 2015	1.0	null
Fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.09857
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44262
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86894
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.345
biological_process	GO Biological Process Annotations 2015	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26289
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29417
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RC-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14995
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48689
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56758
H3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69885
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825799
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
organic cyclic compound catabolic process	GO Biological Process Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hyperoxaluria	HPO Gene-Disease Associations	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82305
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2770-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56327
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38797
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16757
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_12142_KO_Lgals9_ERP122370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.12976
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein homodimerization activity	GO Molecular Function Annotations 2023	1.0	null
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19992
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42154
PMC12511553-41598_2025_19314_MOESM1_ESM.pdf-37-NFATC4_NFATC4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47386
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866728
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20295
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW626	DepMap CRISPR Gene Dependency	1.0	2.87662
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bartter disease type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941431
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01482
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12464
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827506
GSE87299_2_v_3_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16629
Renal tubular acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16772
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10458
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-11A-01R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DES_KO_GDS4804_171_mouse_young skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96674
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857228
HEC116	DepMap CRISPR Gene Dependency	1.0	2.27645
GSE99187_1_v_0_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
absent	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fruit juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
10min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15222
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5059
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12209513-JDI-16-1263-s001.pdf-7-GLIS3_GLIS3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Primary hyperoxaluria	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TP63	ChEA Transcription Factor Targets	1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18439
0min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07042
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.51271
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.60936
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29935
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10622
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Carbohydrate metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901828
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8327
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950971
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
MYOG	ENCODE Transcription Factor Targets	1.0	null
GSE169571_0_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.85212
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
GTEX-XGQ4-2426-SM-4AT55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951188
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Peroxisomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2279
KIJK	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02066
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27937
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92887
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051227
SLC49A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20887
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47215
MOLM6	CCLE Cell Line Gene CNV Profiles	1.0	1.36132
MEG01	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73291
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.5529
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989275
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18259
KRBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24491
SNU1105_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	5.17071
Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960682
OVK18	CCLE Cell Line Gene CNV Profiles	1.0	1.53762
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905419
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06311
IOSE-29 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.275
YJU2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59517
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30917
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4770	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900766
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9434
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A149-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998426
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.2898
Calcium oxalate nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.401
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825826
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7137
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7286-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934896
hsa-miR-3605-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
all	HPO Gene-Disease Associations	1.0	null
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00218
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MES-SA	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.96701
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13482
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22329
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977453
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
heterocycle catabolic process	GO Biological Process Annotations 2023	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984768
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21221
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967584
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980629
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_8587_KO_Adnp_SRP063269	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.8312
abnormal behavior	MGI Mouse Phenotype Associations 2023	1.0	null
single-organism biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41153
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90801
NFYA	ENCODE Transcription Factor Targets	1.0	null
GSE114232_10_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein homodimerization activity	GO Molecular Function Annotations 2015	1.0	null
HNF4A_KD_GDS4798_550_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71248
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.42201
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
outcome	GeneRIF Biological Term Annotations	1.0	null
calcium oxalate nephrolithiasis	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00348
aciduria	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956557
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884157
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955682
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09272
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06077
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01116
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10514
253JBV	CCLE Cell Line Gene Expression Profiles	1.0	1.63824
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53705
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93823
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18757
monocarboxylic acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
MDAMB468	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5425
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18954
monocarboxylic acid biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.11466
Perturb_5155_KD_Mbd3_SRP046299	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32365
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34788
RMGI	DepMap CRISPR Gene Dependency	1.0	2.79166
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04377
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56732
Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42344