association	dataset	threshold value	standardized value
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.961868
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983409
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68891
GSE198165,GSE198166_5_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Xc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.603
GSE206870,GSE206872_4_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
3t3msv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
LFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19775
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48558
hTERT-RPE1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.842
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69438
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09701
DMS273	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.938795
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.522136
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21137
CLOCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18547
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73387
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06663
layer 3 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23585
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07933
LS180	CCLE Cell Line Gene Mutation Profiles	1.0	null
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5486
EPS8L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55221
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54792
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33755
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824578
ZNF415	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93936
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.2032
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Mitotic checkpoint complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
CLSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41164
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_Ruxolitinib_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123193
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16652
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72507
hsa-miR-548ah	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-HIF1A_mod_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
U-2-OS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D341Med	DepMap CRISPR Gene Dependency	1.0	2.09168
Inactive sex chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
Basal-Like Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
vegf	GeneRIF Biological Term Annotations	1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.53577
meiotic sister chromatid cohesion	GO Biological Process Annotations 2015	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01255
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
HOS	CCLE Cell Line Gene CNV Profiles	1.0	1.48259
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18954
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15572
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89424
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983571
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
synaptonemal complex assembly	GO Biological Process Annotations 2025	1.0	null
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15397
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04021
condensed chromosome	GO Cellular Component Annotations 2015	1.0	null
atm	Phosphosite Textmining Biological Term Annotations	1.0	null
20208059-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
A4-FUK	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
Lung squamous cell carcinoma_LUSC_TCGA-34-5240-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15004
reproductive process	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-X6-A8C4-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86347
HCV_8week+IFN-a_None_GSE37715	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45856
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
chromosome organization	GO Biological Process Annotations 2015	1.0	null
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05941
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69113
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06762
small testis	MPO Gene-Phenotype Associations	1.0	null
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0565
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20167
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0447
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52099
Lung adenocarcinoma_LUAD_TCGA-67-4679-01B-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.298
blastocyst development	GO Biological Process Annotations 2015	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
homologous chromosome pairing at meiosis	GO Biological Process Annotations 2025	1.0	null
Complex laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.133
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07114
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895817
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17921
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.516
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83848
mRNA_PANCT1_22327834	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057203
A549_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177066
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09779
Acute Myeloid Leukemia_LAML_TCGA-AB-2888-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10364
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73419
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30016
H4C16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93741
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03008
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19483
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
PPIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27579
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	3.37181
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89932
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HI-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02313
Acrosomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.598
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33987
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cellular component assembly	GO Biological Process Annotations 2025	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4606
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD38	DepMap CRISPR Gene Dependency	1.0	2.22752
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00395
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846343
meiotic sister chromatid cohesion	GO Biological Process Annotations 2023	1.0	null
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
Hereditary spastic paraplegia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
A549_JNJ-7706621_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124318
controls	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02048
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79085
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.505
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.725
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26687
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.404
TGF-beta_OE_GDS2974_137_mouse_corneas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1899
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF341	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70018
Replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.438
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74816
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23769
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.24664
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22346
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.11678
seminiferous tubule degeneration	MPO Gene-Phenotype Associations	1.0	null
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
TCF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3753
PMC3500769-srep00875-s3.xls-CEBP-Time_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Monopolin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.411
MYBL2	ChEA Transcription Factor Targets	1.0	null
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06925
hsa-miR-4803	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68724
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nuclear chromosome part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.94211
PKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67312
Skin carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78434
GABARAPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2442
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26029
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Z-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908276
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1545
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043588
A549_Barasertib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125816
Meiotic septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
Spore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
SLC39A13_Deficiency_GDS3485_570_mouse_Chondrocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11233907-mmc9.xlsx-S8-Table_S8_Colocalization_Analysis_for_MR_TWAS_PWAS_Hits_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18819
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153443_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00088
NECTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15783
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.8808
WM88	DepMap CRISPR Gene Dependency	1.0	2.62505
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21888
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TYW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20929
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26736
Perturb_5331_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.80644
A549_Belinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114249
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5896
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39457
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.0841
condensed nuclear chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70121
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56868
Perturb_6388_KO_Mettl3_SRP254797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.1549
LN428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71511
failure of embryo implantation	MGI Mouse Phenotype Associations 2023	1.0	null
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.703
sister chromatid cohesion	GO Biological Process Annotations 2015	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.872
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950595
hsa-miR-2276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44154
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19456
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU738	DepMap CRISPR Gene Dependency	1.0	2.22384
CAOV4	CCLE Cell Line Gene CNV Profiles	1.0	1.81798
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
remain	GeneRIF Biological Term Annotations	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61422
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02613
GTEX-XQ8I-1526-SM-4BOOH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29238
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31329
bub1-bub3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
CREM	ChEA Transcription Factor Targets	1.0	null
Metaphase plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45704
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1348
U2-type prespliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
Primary somatosensory area, unassigned, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33265
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.91204
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153071
GSE158285_0_v_1_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
meiotic sister chromatid cohesion	GO Biological Process Annotations 2025	1.0	null
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
abnormal embryo implantation	MPO Gene-Phenotype Associations	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94149
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.794
cell cycle process	GO Biological Process Annotations 2015	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.47497
breast	Phosphosite Textmining Biological Term Annotations	1.0	null
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95052
regulation of chromosome segregation	GO Biological Process Annotations 2015	1.0	null
PDIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4079
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
Lymphocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.8
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75037
lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.356341
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21004
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.715
8505C	DepMap CRISPR Gene Dependency	1.0	2.04268
abnormal male genitalia morphology	MPO Gene-Phenotype Associations	1.0	null
GSE193258,GSE193259_5_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
HEC251	CCLE Cell Line Gene Mutation Profiles	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
male	Phosphosite Textmining Biological Term Annotations	1.0	null
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
aneuploidy	MPO Gene-Phenotype Associations	1.0	null
GSE193258,GSE193259_9_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS53	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63614
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12374
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74642
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960607
PUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40058
SRRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22713
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930843
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02592
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.156
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06714
meiotic DNA double-strand break formation	GO Biological Process Annotations 2025	1.0	null
RALDH2_KO_GSE43578_6_mouse_head (rostral or posterior)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07984
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2365
single-stranded DNA-binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
Ndc80 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Embryonic stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
NO11	DepMap CRISPR Gene Dependency	1.0	2.85623
NR5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42502
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.356324
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26423
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20969
abnormal meiosis	MPO Gene-Phenotype Associations	1.0	null
A549_Glesatinib(MGCD265)_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195765
Filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.852
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78813
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDKN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43257
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73965
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01909
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.632024
SNU489	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34548
Trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Perturb_5153_KD_Dcp1a_SRP014645	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.66923
TRIM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45426
PSIP1_Deficiency_GDS2883_633_human_T-cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58617
Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.643
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
meiotic DNA double-strand break formation	GO Biological Process Annotations 2023	1.0	null
OCUG1	DepMap CRISPR Gene Dependency	1.0	3.16294
histone	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62227
aneuploidy	MGI Mouse Phenotype Associations 2023	1.0	null
however	GeneRIF Biological Term Annotations	1.0	null
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08008
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61333
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.938834
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11643
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03805
Piriform area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61155
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2479
Lung squamous cell carcinoma_LUSC_TCGA-58-A46M-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
lateral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19841
LY6E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92796
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
Cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.451
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46396
HT-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.842
abnormal oogenesis	MPO Gene-Phenotype Associations	1.0	null
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Aurora A Inhibitor I_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118102
FERD3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03761
spermatogenesis	GeneRIF Biological Term Annotations	1.0	null
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43541
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32771
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850262
ERCC4-ERCC1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35891
ART5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44639
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6821
Urogenital ridge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33247
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9381
RTL8C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83512
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8616-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56517
RNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7077
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52291
hsa-miR-4528	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56876
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3609
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972776
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.901215
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46454
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85352
abnormal cell nucleus morphology	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10818
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7329
LB771HNC	DepMap CRISPR Gene Dependency	1.0	2.21602
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.498
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07375
RNASE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33372
metabolic process	GO Biological Process Annotations 2015	1.0	null
HNF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99249
GSE193993_1_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.940995
GTEX-UJMC-0926-SM-4IHLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05159
A549_Lomustine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181382
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.133
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38681
CJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61406
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.41866
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78549
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02664
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29092
female infertility	MPO Gene-Phenotype Associations	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927499
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.375
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10513
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00988
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7932
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24149
HUH7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75184
hsa-miR-4477a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4756
Translation initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
chr1_150827614_T_G_b38	GTEx eQTL 2025	1.0	1.07111
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1055
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.9328
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cisplatin_mus musculus_gpl6887_gse35257	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chromosome, telomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.422
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9239
atf1-pcr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383509
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69879
Sarcoma_SARC_TCGA-QQ-A5V9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67158
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
abnormal cell death	MPO Gene-Phenotype Associations	1.0	null
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07053
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.46
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.994
PMC3721393-bjc2013326x2.xls-Breast_Cancer_SOX10_Gene_Sig-Unnamed_1_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6869-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31636
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47495
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09586
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04188
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06433
Microtubule organizing center attachment site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.413
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21649
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980949
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1878
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26036
embryogenesis phenotype	MPO Gene-Phenotype Associations	1.0	null
Germarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
alpha-heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.027
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_U2OS_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
negative regulation of nuclear division	GO Biological Process Annotations 2015	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64137
JHH7	DepMap CRISPR Gene Dependency	1.0	2.74137
Lung adenocarcinoma_LUAD_TCGA-78-7220-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06243
superficial stratum of InsCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82797
MutSbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
LGI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39423
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.519647
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68495
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.293
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC38	CCLE Cell Line Gene Expression Profiles	1.0	2.15126
XBP1_OE_GDS5065_273_mouse_F424a adipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.47268
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z4-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1-C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3143	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59602
Agranular insular area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35999
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.406
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63882
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.68892
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.297
HEC108	CCLE Cell Line Gene Mutation Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
Germinal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.359371
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26753
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13036
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
DNA packaging complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.371
GTEX-P4PP-0626-SM-3NM9X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922641
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.08381
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85119
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
A549_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0225004
ATF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30312
Azoospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
SEPTIN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31886
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.35457
BRCA1-BARD1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microvessel	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNOS-0626-SM-4DM5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15463
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68098
relationships	GeneRIF Biological Term Annotations	1.0	null
abnormal female meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	1.43543
SLC18A3_KD_GDS4325_618_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-7755-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65686
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21174
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0106
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.95187
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830899
Perturb_7583_KO_MBD6_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.7802
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
PRDM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38787
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09955
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889087
Late recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.643
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7327
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49554
ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16102
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85406
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
STK31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27746
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7557
regulation of meiosis	GO Biological Process Annotations 2015	1.0	null
Zygotene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.352
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158951
pre-replicative complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76199
HCC44	DepMap CRISPR Gene Dependency	1.0	2.82995
AGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34029
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMS-11/TKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.911579
Brain Lower Grade Glioma_LGG_TCGA-HT-8013-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07837
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06216
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00871
Mre11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.929
A549_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164406
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82022
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
ACCMESO1	DepMap CRISPR Gene Dependency	1.0	2.79514
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42107
Sarcoma_SARC_TCGA-DX-A3LW-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21903
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915349
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9585724-12916_2022_2610_MOESM2_ESM.xlsx-ST12_-_MediationRatioStromalSCT-Unnamed_5_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
SKNMM	DepMap CRISPR Gene Dependency	1.0	2.34749
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83651
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065379
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38769
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.579251
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9996
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
IMR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88305
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91765
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31239
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950595
Condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.916
Lung adenocarcinoma_LUAD_TCGA-78-7539-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40091
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63428
singlenucleotide	GeneRIF Biological Term Annotations	1.0	null
3t3sv40	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954653
Perturb_1388_KO_Tet1/3_ERP010627	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.77414
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.811
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2667
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8469
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05252
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40821
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.92587
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.105
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5409
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19019
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33094
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.919
PMC6484770-41388_2018_602_MOESM5_ESM.xlsx-down_P53_vs_con-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837432
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
16729877-GeneTable	GeneSigDB Published Gene Signatures	1.0	null
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33791
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905361
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1568	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CHLA57	DepMap CRISPR Gene Dependency	1.0	3.63752
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
CAOV-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983409
abnormal embryogenesis/ development	MPO Gene-Phenotype Associations	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28707
Sarcoma_SARC_TCGA-DX-A1KU-01A-32R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6342-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOS	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HO-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COMMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52471
EID2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39032
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.357
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137717
MOLM14	DepMap CRISPR Gene Dependency	1.0	2.96483
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
Central element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.043
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893456
insular cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82537
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0694
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08584
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUDT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73439
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81621
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18287
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24706
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45158
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67368
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02444
embryonic growth arrest	MPO Gene-Phenotype Associations	1.0	null
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13847
increased male germ cell apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32749
A549_Crizotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120835
hsa-miR-29c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0767
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96836
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.761984
abnormal female meiosis I arrest	MGI Mouse Phenotype Associations 2023	1.0	null
LK2	CCLE Cell Line Gene CNV Profiles	1.0	1.50742
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23409
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1429
abnormal gametogenesis	MPO Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40595
HS852T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63438
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48287
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73063
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.245175
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.981
LNZ308	CCLE Cell Line Gene CNV Profiles	1.0	2.20921
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28202
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1623
A549_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014791
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85547
OVOL2_01_313	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.50703
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05202
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Caffeine consumption from tea	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.922185
Meiotic spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.419
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39036
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853477
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875928
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052309
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23948
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147748
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2ES-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
59M	DepMap CRISPR Gene Dependency	1.0	3.04454
TSC1_Deficiency_GDS4572_347_mouse_Naive CD8 T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907306
Nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.947
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.68983
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.926691
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38961
hsa-miR-1182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5842
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
RHJT	DepMap CRISPR Gene Dependency	1.0	3.30855
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050198
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
16651414-Supp4	GeneSigDB Published Gene Signatures	1.0	null
snps	GeneRIF Biological Term Annotations	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Syp1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.188
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86137
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907277
cellular process	GO Biological Process Annotations 2015	1.0	null
TRIM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35081
hsa-miR-548ag	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08163
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
TDG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49276
Pairing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.159
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999221
Kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.057
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
Site of DNA damage	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
cSARS Bat SRBD_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.565
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24317
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23386
hsa-miR-323-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
Pericentric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.439
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857476
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27714
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03518
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
Hereditary nonpolyposis colorectal cancer type 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
Sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
ZSCAN22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79973
Mammary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
PEO4	DepMap CRISPR Gene Dependency	1.0	2.57672
Germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.994
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61818
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.333
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5333_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.8298
NCIH841	CCLE Cell Line Gene Mutation Profiles	1.0	null
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.11678
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950595
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893878
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07479
abnormal spermatogenesis	MPO Gene-Phenotype Associations	1.0	null
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC1F	CCLE Cell Line Gene Expression Profiles	1.0	1.5941
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
PMC7041704-JEM_20180649_TableS1.xlsx-IL10_rescued_LPS_downregulated-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ERRalpha_Deficiency_GDS2727_646_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	4.92192
Perturb_8756_OE_CCNE1_SRP314351	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.64366
MCM8-MCM9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.217
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2285
MKN45	CCLE Cell Line Gene Expression Profiles	1.0	1.67359
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925556
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35346
infertility	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNA metabolic process	GO Biological Process Annotations 2025	1.0	null
NCIH1623	CCLE Cell Line Gene Expression Profiles	1.0	1.95757
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2GZ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2716
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826751
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.789
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0858
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10846
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00309
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75557
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03397
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46293
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828261
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825843
DNA repair complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.707
HCC1143	CCLE Cell Line Gene Expression Profiles	1.0	1.43666
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14091
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23222
Micronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79946
EP300	ENCODE Transcription Factor Targets	1.0	null
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.786
BICR22	CCLE Cell Line Gene Expression Profiles	1.0	1.83601
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37365
A549_Tubastatin A HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157981
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82047
SW48	CCLE Cell Line Gene Mutation Profiles	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877928
PRKCA_KO_GDS2141_300_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFJO-2026-SM-4LVM3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906454
Y-linked spermatogenic failure 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8123
nucleic acid phosphodiester bond hydrolysis	GO Biological Process Annotations 2023	1.0	null
jvm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00921
CDIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89769
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899431
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.91699
FABP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78243
MFSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49941
A549_Alisertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132499
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22685
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14922
cellular component assembly	GO Biological Process Annotations 2023	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08454
GSE194268_2_v_0_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovarian	GeneRIF Biological Term Annotations	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6528
maternal effect	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-3177-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.547
Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61352
NCIH1395	CCLE Cell Line Gene Expression Profiles	1.0	1.74789
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
cancer	Phosphosite Textmining Biological Term Annotations	1.0	null
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20626
CLDN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
ADAMTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61723
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02819
KMS11	CCLE Cell Line Gene CNV Profiles	1.0	1.36352
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
vagina	HPA Tissue Protein Expression Profiles	1.0	0.979771
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
LPIN1_OE_GDS2291_587_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Condensed chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.057
SET2	DepMap CRISPR Gene Dependency	1.0	2.77554
DASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.933
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80211
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
PMC5637904-PATH-243-193-s015.xlsx-human_up_in_ductal_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
colo857	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5834
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15055
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ST3GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72185
Sporulating cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
testis	GeneRIF Biological Term Annotations	1.0	null
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
MYF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06452
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1639
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96708
A549_G007-LK_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.020782
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81368
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Endopiriform nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25993
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE73381,GSE73382_0_v_1_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10947
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75597
PMC9207509-DataSheet_1.docx-3-FOXK1_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35106
abnormal gland morphology	MPO Gene-Phenotype Associations	1.0	null
regulation of organelle organization	GO Biological Process Annotations 2015	1.0	null
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	2.53088
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7849
signal	Phosphosite Textmining Biological Term Annotations	1.0	null
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.254
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anaphase-promoting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.601
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30344
18676831-Table1	GeneSigDB Published Gene Signatures	1.0	null
hormad2	GeneRIF Biological Term Annotations	1.0	null
CALR_KO_GDS3680_149_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
chromosome, telomeric repeat region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77244
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04006
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48147
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.461078
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.036
abnormal testis morphology	MPO Gene-Phenotype Associations	1.0	null
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69092
basomedial amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6349
Perturb_9471_KO_Il1rl1_SRP274117	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.521432
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.57485
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCIH2110	CCLE Cell Line Gene Expression Profiles	1.0	3.40781
Nuclear MIS12/MIND complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11914
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nuclear division	GO Biological Process Annotations 2015	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21289
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.951169
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60438
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99639
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19442
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888071
MYL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4111
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99012
VCY1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40782
abnormal female meiosis i arrest	MPO Gene-Phenotype Associations	1.0	null
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.817
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15962
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Rhegmatogenous retinal detachment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04465
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864493
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2955
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.553
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32203
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840917
KMRC3	CCLE Cell Line Gene Mutation Profiles	1.0	null
nucleic acid phosphodiester bond hydrolysis	GO Biological Process Annotations 2015	1.0	null
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11323
ZSCAN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31775
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3066
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27604
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95833
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18736
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BN-01B-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29436
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59131
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65121
SNU1040	CCLE Cell Line Gene Mutation Profiles	1.0	null
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Embryonal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AV-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4286
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G3-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112762,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73998
Epiblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.359
density	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89795
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09965
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03418
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
ChIP_SOX2_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.911492
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.983723
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02822
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26405
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
multicellular organismal reproductive process	GO Biological Process Annotations 2015	1.0	null
DNA polymerase III, clamp loader complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.718
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851799
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.667
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.32896
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7652-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
Central amygdalar nucleus, capsular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54487
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958533
Morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33058
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98871
A549_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154191
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32712
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5733
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81232
NCIH1781	CCLE Cell Line Gene Expression Profiles	1.0	1.71154
hsa-miR-3609	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.736
A549_Nintedanib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188034
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39934
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27243
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64104
Embryonic germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
SETDB1_KO_GSE40296_7_mouse_brain (telencephalon)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.056792
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29202
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49098
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983057
Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7969
meiotic recombination checkpoint signaling	GO Biological Process Annotations 2023	1.0	null
ADH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20343
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
DUSP1_KO_GDS1606_772_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23707
negative regulation of cell cycle	GO Biological Process Annotations 2015	1.0	null
GATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62177
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76237
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74579
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866654
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05399
mechanistic	GeneRIF Biological Term Annotations	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76805
SOX2-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ES4	DepMap CRISPR Gene Dependency	1.0	2.67368
sirolimus_rattus norvegicus_gpl6247_gse35048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5055179-CAM4-5-2522-s008.xlsx-S1-Supplementary_Table_S1_Properties_of_genes_upregulated_by_MBD-TET1-CDwt_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59446
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06318
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39001
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neutrophil percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.70458
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12607
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5172_KO|KD_Sirt1|Otx2_SRP075247	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
embryonic growth arrest	MGI Mouse Phenotype Associations 2023	1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
seminiferous tubule degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
SUM-159PT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.393
SRY	ChEA Transcription Factor Targets	1.0	null
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17454
A549_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0244431
C1QBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92318
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
chromosome	Phosphosite Textmining Biological Term Annotations	1.0	null
CAL-51 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26797
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06056
A549_MLN8054_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124144
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUM149PT	DepMap CRISPR Gene Dependency	1.0	2.13327
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43293
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_6584_KO_Clpp_SRP114840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.99953
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26355
A549_GSK J1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145131
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.303781
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Parasubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09585
Shelterin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
Sex chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.025
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59085
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971602
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97119
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
Piriform area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27197
Perturb_17307_KD_Chrm5_SRP222274	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.37086
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40118
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myosin XII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40387
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03061
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26883
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22261
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.724943
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876721
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96251
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.462626
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08608
RAB3A_KO_GDS2482_706_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of chromosome segregation	GO Biological Process Annotations 2023	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32144
UHO1	DepMap CRISPR Gene Dependency	1.0	2.08563
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.585
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
Perturb_12599_KD_Gatad2b_SRP366371	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.16444
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26753
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29119
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60416
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02806
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00665
variant	GeneRIF Biological Term Annotations	1.0	null
synaptonemal complex organization	GO Biological Process Annotations 2025	1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
Chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.529
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7135
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55882
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2311
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29274
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.36933
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07341
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.23
nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.01238
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.024136
Lung adenocarcinoma_LUAD_TCGA-86-8056-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
silencing	GeneRIF Biological Term Annotations	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927857
abnormal male meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
AMO-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
maternal effect	MGI Mouse Phenotype Associations 2023	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.19878
regulation of homologous chromosome segregation	GO Biological Process Annotations 2015	1.0	null
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00045
ABHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90799
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
homologous chromosome pairing at meiosis	GO Biological Process Annotations 2023	1.0	null
DNA recombinase mediator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94431
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04497
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056715
GSE120413,GSE120447_3_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58361
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028359
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2042
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
organelle part	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068011
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9935
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XM-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956656
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.694
NB7	DepMap CRISPR Gene Dependency	1.0	6.35451
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTARC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78623
TSPAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97914
abnormal pregnancy	MPO Gene-Phenotype Associations	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919585
PK1	DepMap CRISPR Gene Dependency	1.0	3.27698
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
CLPSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61877
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51062
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45213
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BE-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2053	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39239
A549_Fasudil_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.019126
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.52672
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
DNA recombinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.438
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3525
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26226
Embryonic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1392
HG3	DepMap CRISPR Gene Dependency	1.0	3.07665
Blastocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6495
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14397
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CMAH_KO_GDS4200_114_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28846
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8803
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23301
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10996
decreased testis weight	MGI Mouse Phenotype Associations 2023	1.0	null
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.0446
A549_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150214
CAL-85-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of meiotic cell cycle	GO Biological Process Annotations 2015	1.0	null
abnormal testis weight	MPO Gene-Phenotype Associations	1.0	null
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3747
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40268
Stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.912
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73677
Female pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32848
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946153
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9983
Delta DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.974
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69208
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2472
hsa-miR-676	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Granulosa cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
endocrine/exocrine gland phenotype	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ES-E14 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
Agranular insular area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39753
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSS	DepMap CRISPR Gene Dependency	1.0	3.12256
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subcortical maternal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
GSE193993_5_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08363
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837003
adaptor-proteins-signal-transducing	Phosphosite Textmining Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162896
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20985
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37717
causal	GeneRIF Biological Term Annotations	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34233
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.939495
Fanconi anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
Spermatogenic failure 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
L363	DepMap CRISPR Gene Dependency	1.0	2.31894
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398735
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64999
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923286
TGIF	MotifMap Predicted Transcription Factor Targets	1.0	null
A549_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129614
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MV411	CCLE Cell Line Gene Expression Profiles	1.0	1.56042
brca1	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11082
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08697
esophagus	GTEx Tissue Gene Expression Profiles	1.0	1.00115
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51461
A549_Glesatinib(MGCD265)_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140122
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9846
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Amp_AA-TCGA-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11472
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95359
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89838
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
damage	Phosphosite Textmining Biological Term Annotations	1.0	null
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89579
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	1.89986
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.874
nucleus	GO Cellular Component Annotations 2025	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.18172
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67047
Perturb_5211_KO_Pten_SRP154291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.08026
rs718772	GeneRIF Biological Term Annotations	1.0	null
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
abnormal gametes	MPO Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43527
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
synaptonemal complex assembly	GO Biological Process Annotations 2023	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.991
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23377
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96038
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58902
Obstructive sleep apnea_Hepatic Tissue_GSE1873	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.59098
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00093
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83222
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51E-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of meiosis i	GO Biological Process Annotations 2015	1.0	null
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10929
abnormal dna repair	MPO Gene-Phenotype Associations	1.0	null
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413151
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38866
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67516
NF-Y	MotifMap Predicted Transcription Factor Targets	1.0	null
Synovial sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79454
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
NHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08869
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.421
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30355
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0483
men	GeneRIF Biological Term Annotations	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10942
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.912553
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00005
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.38972
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31125
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92054
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983409
Perturb_5040_KD_Smarcc1_SRP221174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.1549
GAL3ST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20009
HOXD9_01_70	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.17092
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08537
LN443	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43384
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.292
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3105
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892371
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08932
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01356
HGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71978
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53959
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29814
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29814
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LN-428 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842488
SYCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50365
Multiple sclerosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.722185
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-BRCA_AND_CESC_AND_UCEC_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3500769-srep00875-s3.xls-PAX2-Time_24_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8752721-42003_2021_2991_MOESM4_ESM.xlsx-Fig3_E2F2-gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23409
defect	GeneRIF Biological Term Annotations	1.0	null
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.14899
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cyclin B1-CDK1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
Polytene chromosome chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	0.913188
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.75299
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.703
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98355
E2F3_KD_GDS4094_448_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-1.00603
Agranular insular area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24192
Dense nuclear body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.334
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15685
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04466
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55829
primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2723
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6972
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06724
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1377
HEC265	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97923
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860504
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
N4BP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89074
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41073
PMC9177993__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06204
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87004
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75299
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-y_TFEB_KO_LLOMe_VS_WTLLOMe_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34735
ZNF91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68426
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24783
EEF1AKMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98657
Heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.771
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37704
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04168
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967909
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
PITPNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.887
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05308
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.372743
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03518
DNA ligase IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12938
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17907
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93361
male gamete generation	GO Biological Process Annotations 2015	1.0	null
Char syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89997
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.227
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34584
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54541
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870682
PARD6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02729
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arrest of male meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
DNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01711
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86488
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52137
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.00936
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85723
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB361	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78619
absent germ cells	MPO Gene-Phenotype Associations	1.0	null
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90655
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19619
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872824
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14894
A549_Anacardic Acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014786
MAFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05193
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043508
KARPAS-299	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17544
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	2.59963
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873485
HDLM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12141
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.188
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05468
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71315
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08791
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.569
HCC2218	CCLE Cell Line Gene CNV Profiles	1.0	1.48507
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.43387
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93802
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rad51B-Rad51C-Rad51D-XRCC2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64839
Perturb_5093_KO_Mga_SRP078684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.56665
chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hsa-miR-655	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
showing	GeneRIF Biological Term Annotations	1.0	null
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.582
SNGM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64801
intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6228-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_PD98059_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168987
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
B3GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68735
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947162
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7528
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56145
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.935
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47069
Organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.452
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
SC-6233 (ATF2)	NURSA Protein Complexes	1.0	null
abnormal female meiosis	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75299
OAZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98409
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72687
MACIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32669
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42858
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09891
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3538
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76406
nucleus	GO Cellular Component Annotations 2023	1.0	null
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-2.75324
SeAx cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
arrest of spermatogenesis	MPO Gene-Phenotype Associations	1.0	null
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25281
Get-1_Deficiency_GDS2629_161_mouse_embryonic skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Endodeoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.984
SW1116	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38903
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	3.30124
hsa-miR-522	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
abnormal male meiosis	MPO Gene-Phenotype Associations	1.0	null
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83032
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30082
RNF19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66681
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08537
organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4235
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.637759
lateropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19593
abnormal meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.610838
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40748
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS20	CCLE Cell Line Gene CNV Profiles	1.0	1.60709
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50084
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87887
negative regulation of meiotic nuclear division	GO Biological Process Annotations 2023	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983409
ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.084292
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5021
Brain Lower Grade Glioma_LGG_TCGA-HT-7689-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.51
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
furan	CTD Gene-Chemical Interactions	1.0	null
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09099
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2367
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
negative regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446422
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66715
BT-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_766_mouse_Skin - 0 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Perturb_5335_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.3033
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02587
MutS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.466
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90393
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6181
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55142
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74575
oogenesis	GO Biological Process Annotations 2025	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17991
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0956
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.364454
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48033
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05184
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10104
Outer kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888071
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.53
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07375
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21649
regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
gene-expression-regulation	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-PLZ5-0926-SM-3TW8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15772
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171845_4_v_2_ccne1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
RSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90887
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BL-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zeta DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
NMS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
Swi5-Sfr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.239
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5643
male infertility	MGI Mouse Phenotype Associations 2023	1.0	null
Spermatogenic failure 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.044
YAP_OE_GDS3220_32_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
chr1_150743306_G_A_b38	GTEx eQTL 2025	1.0	1.83281
RAB11FIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97782
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71024
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09779
azoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92532
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.374666
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48558
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03037
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49233
mantle zone of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19755
Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43204
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.898
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8023-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.75
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.80646
MPP-89	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990355
BCPAP	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07437
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170888
Primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.891
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14169
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09144
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
OLFML2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5787431__F2	PFOCR Pathway Figure Associations 2023	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20628
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43713
NCI-H345	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
Germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03098
Chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20336
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal double-strand dna break repair	MPO Gene-Phenotype Associations	1.0	null
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942569
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5668
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10722
hsa-miR-374c	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Shu complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3625
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06721
Lung adenocarcinoma_LUAD_TCGA-05-4382-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.1843
basolateral amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08317
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825843
A549_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162287
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81683
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUGC3	CCLE Cell Line Gene Mutation Profiles	1.0	null
GATA4_KO_GDS3486_483_mouse_jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64193
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96034
POLR3A_01_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.22882
SHREC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
FUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90987
ZBED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40533
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.366
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22482
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81475
BHY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34938
H3-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73527
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99346
Sad1-Kms1 LINC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.229
A549_Tazemetostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121243
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_symbol_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57371
meiotic recombination checkpoint	GO Biological Process Annotations 2015	1.0	null
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
STAT3	ChEA Transcription Factor Targets	1.0	null
COLO-320-HSR	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18369
Internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.256
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.203699
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86954
cell cycle checkpoint	GO Biological Process Annotations 2015	1.0	null
chromatin	Phosphosite Textmining Biological Term Annotations	1.0	null
synaptonemal complex organization	GO Biological Process Annotations 2015	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143288
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.54982
RT112	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49549
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67303
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888071
chromosome	GO Cellular Component Annotations 2025	1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991091
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063815
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993254
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32934
Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FI-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860976
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39082
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33079
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.796041
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_Ensembl_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.988
hsa-miR-556-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
abnormal germ cell morphology	MPO Gene-Phenotype Associations	1.0	null
HCC1187	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_Luminespib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00982461
ZNF610	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44176
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22642
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01865
CUX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68696
single-organism process	GO Biological Process Annotations 2015	1.0	null
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37635
cSARS Bat SRBD_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.53183
female gamete generation	GO Biological Process Annotations 2025	1.0	null
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894811
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3157-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042436
NCIH1573	CCLE Cell Line Gene Expression Profiles	1.0	1.48617
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37403
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2471
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal sex determination	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
DDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04298
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.982904
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29917
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052168
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18325
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82428
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64922
meiotic nuclear division	GO Biological Process Annotations 2015	1.0	null
IRX1_01_227	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.76472
mammals	Phosphosite Textmining Biological Term Annotations	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41912
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45806
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61054
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09338
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.280796
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94248
COLO775	CCLE Cell Line Gene Mutation Profiles	1.0	null
Agranular insular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08756
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
A549_Roxadustat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114207
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03283
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19229
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04785
PBX1	ChEA Transcription Factor Targets	1.0	null
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849445
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72177
LinE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.138
Acute Myeloid Leukemia_LAML_TCGA-AB-2985-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995728
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6192992__F6	PFOCR Pathway Figure Associations 2023	1.0	null
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.134
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5909
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10264
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15207
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842488
SKLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49485
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0569
abnormal testis morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7911
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64269
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835608
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1826
BMPR1A_knockout_222_GSE48092	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.27341
Triple Negative Breast Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Fulvestrant_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015353
HCC1806	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74509
GSE198165,GSE198166_0_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Site of double-strand break	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1863
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06316
PMC11995938-74_129_TableS2.pdf-2-GTF2B_GTF2B	Rummagene Transcription Factor Associations 2026	1.0	null
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
Nuclear envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
hsa-miR-4676-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83439
PMC10290283-biol-2022-0622-sm3.pdf-124-ZFP1_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.227
46 XX gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
496100591_TCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7953
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
HCT15	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
APCDD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0901
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10818
PMC3500769-srep00875-s3.xls-AP1-Time_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
predispose	GeneRIF Biological Term Annotations	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4564_KD_Uhrf1_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.53526
PMC7576141-41598_2020_74792_MOESM7_ESM.xlsx-CBX2-Unnamed_5_CBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835283
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78218
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
GATA1	ChEA Transcription Factor Targets	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.51994
A549_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182651
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76132
hsa-miR-4512	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.48
ZNF776	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71584
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94226
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4976
Lung adenocarcinoma_LUAD_TCGA-MP-A4TK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nuclear lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.566
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94541
LNZTA3WT4	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7521-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07145
PATU8988S	DepMap CRISPR Gene Dependency	1.0	3.01006
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2549
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.60467
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61368
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23842
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.756
NP2	DepMap CRISPR Gene Dependency	1.0	3.29645
RUFY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35245
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02088
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13757
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WEHI-3B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.8008
pdx1_22135308_duodenum_lof_mouse_gpl1261_gds4348	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.498884
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04511
Perturb_5011_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.6479
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02377
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68982
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29341
abnormal double-strand DNA break repair	MGI Mouse Phenotype Associations 2023	1.0	null
report	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968136
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33161
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21399
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35661
SESN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93288
kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070185
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60719
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22085
Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87493
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.680656
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.374
Distal tip cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79092
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95526
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RERFGC1B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6435
MYC	ChEA Transcription Factor Targets	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99939
Caffeine consumption from coffee or tea	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.6
TUBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64816
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54711
A549_TMP195_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134108
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64758
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5736
TRAPPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99229
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857769
C2CD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54406
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88194
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00505
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51764
abnormal chromosomal synapsis	MGI Mouse Phenotype Associations 2023	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836123
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_767_mouse_Skin - 1 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	2.52172
TTC642	DepMap CRISPR Gene Dependency	1.0	4.1207
SUDHL8	DepMap CRISPR Gene Dependency	1.0	6.82371
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
azoospermia	MPO Gene-Phenotype Associations	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920315
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Cortical subplate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00735
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2332
KYSE70	CCLE Cell Line Gene Expression Profiles	1.0	1.51017
azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.942443
Kidney Chromophobe_KICH_TCGA-KL-8342-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
Turner syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
intracellular part	GO Cellular Component Annotations 2015	1.0	null
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HIF1A_01_156	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61374
GSE155087_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
gamma-tubulin large complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
negative regulation of meiotic nuclear division	GO Biological Process Annotations 2015	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90416
VAMP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38192
ZFPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51232
epigenetic	Phosphosite Textmining Biological Term Annotations	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5109_OE_Trim66_SRP311833	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.9752
MYB	JASPAR Predicted Transcription Factor Targets	1.0	null
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62873
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50018
male infertility	MPO Gene-Phenotype Associations	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18244
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17459
NCIH810	CCLE Cell Line Gene CNV Profiles	1.0	1.44962
organelle organization	GO Biological Process Annotations 2015	1.0	null
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7379
EIF4ENIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77114
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5503-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11531
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056346
Isocortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03952
Acute Myeloid Leukemia_LAML_TCGA-AB-2837-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATR-ATRIP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
GSE147366_3_v_5_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192487
Theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.761047
TXNDC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56768
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24673
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFO27	CCLE Cell Line Gene Mutation Profiles	1.0	null
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.205
HCC1937	CCLE Cell Line Gene Expression Profiles	1.0	1.72085
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GMPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46566
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.274
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95846
resulted	GeneRIF Biological Term Annotations	1.0	null
abnormal synaptonemal complex	MPO Gene-Phenotype Associations	1.0	null
susceptible	GeneRIF Biological Term Annotations	1.0	null
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44943
Spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.459
UACC257	DepMap CRISPR Gene Dependency	1.0	2.17586
Granulosa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.082472
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50837
abnormal primary sex determination	MPO Gene-Phenotype Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44454
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983855
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96322
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24018
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868332
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02395
Male germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28671
SCC9	DepMap CRISPR Gene Dependency	1.0	2.70948
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CJ-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kinetochore microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
cSARS Bat SRBD_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.62388
PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03362
Synovium cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070008
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13348
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74992
GTEX-WEY5-0926-SM-4LMI4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12513
SLR20	DepMap CRISPR Gene Dependency	1.0	2.17657
PMC5637904-PATH-243-193-s015.xlsx-human_up_in_ductal_SOX11-Table_S4A_Upregulated_genes_in_lesions_and_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_the_mammary_duct_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
NCOA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62065
Lung squamous cell carcinoma_LUSC_TCGA-39-5016-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70153
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17705
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8473
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99942
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.301
A549_Temsirolimus_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137303
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828888
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.127
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34856
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01591
A1207	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72951
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.12048
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77238
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94423
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824841
SMCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92235
Agranular insular area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59525
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.017
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26763
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69252
Sarcoma_SARC_TCGA-DX-A3LT-01A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15192
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.4275
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949246
Mitotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.87
496100297_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00197
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
absent gametes	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.27444
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0866
checkpoint	Phosphosite Textmining Biological Term Annotations	1.0	null
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF460	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81345
SMAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07061
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860459
abnormal synaptonemal complex	MGI Mouse Phenotype Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151192
GSE165307_3_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-824	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40365
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.821179
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.89
RNA polymerase II termination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26592
NCIH1930	CCLE Cell Line Gene Mutation Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
WPE1NA22	DepMap CRISPR Gene Dependency	1.0	3.28618
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A5-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mesonephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
RAP1GAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37367
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226355,GSE226357_2_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.937
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89388
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61161
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65961
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9742
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40091
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48287
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90626
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTAGE15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32053
HCC70	CCLE Cell Line Gene Expression Profiles	1.0	2.23443
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08685
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44212
Recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.278
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28549
A549_S3I-201_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158893
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
pre-primosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
BT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04021
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88801
Telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08127
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal preimplantation embryo development	MPO Gene-Phenotype Associations	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64902
hsa-miR-338-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE198165,GSE198166_7_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.5613
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1876	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
unclear	GeneRIF Biological Term Annotations	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24669
NCIH838	CCLE Cell Line Gene Expression Profiles	1.0	1.41142
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983409
pi-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7971
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21981
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
repressor-proteins	Phosphosite Textmining Biological Term Annotations	1.0	null
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39053
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20165
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43612
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21025
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9416
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
abnormal preimplantation embryo development	MGI Mouse Phenotype Associations 2023	1.0	null
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01513
negative regulation of meiotic nuclear division	GO Biological Process Annotations 2025	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06626
ABCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
MDA-MB-436 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
SRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19564
developmental process involved in reproduction	GO Biological Process Annotations 2015	1.0	null
Spermatogenic failure 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
OPM2	CCLE Cell Line Gene CNV Profiles	1.0	1.42855
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877445
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.72238
A549_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122318
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888071
non-small cell lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.098512
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23086
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24711
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7409-01A-31R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
nonobstructive	GeneRIF Biological Term Annotations	1.0	null
TSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27181
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
meiotic recombination checkpoint signaling	GO Biological Process Annotations 2025	1.0	null
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27441
J82	DepMap CRISPR Gene Dependency	1.0	3.03208
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36596
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05252
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5010_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.699
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.69629
hsa-miR-338-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
LN464	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01381
U2OS	CCLE Cell Line Gene Mutation Profiles	1.0	null
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-1.11678
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79874
RIF1_KD_GDS4943_13_mouse_J1 ESC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
A549_2-Methoxyestradiol_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174572
8505C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33442
Male infertility	WikiPathways Pathways 2024	1.0	null
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
gamete generation	GO Biological Process Annotations 2015	1.0	null
meiotic cell cycle checkpoint	GO Biological Process Annotations 2015	1.0	null
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31115
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9931
me96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.297651
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953406
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1236
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COL18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90257
GTEX-XV7Q-1126-SM-4BRVS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883233
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45321
regulation of cell cycle process	GO Biological Process Annotations 2015	1.0	null
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95566
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61494
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34158
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0229
TMEM145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.764
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957668
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1097
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7376
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39791
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92973
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.979771
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80393
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6055
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24947
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03028
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32294
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73Q-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesenterial filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24554
Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GU-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.979771
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.53325
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRCA1-A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.247
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00108
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17803
NCIH1666	CCLE Cell Line Gene Expression Profiles	1.0	1.72325
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89114
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21593
GSE147366_3_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55475
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal chiasmata formation	MPO Gene-Phenotype Associations	1.0	null
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68769
germ cell development	GO Biological Process Annotations 2015	1.0	null
Phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.851
abnormal chromosome number	MPO Gene-Phenotype Associations	1.0	null
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.041173
Nuclear membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.433
COX5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56579
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
EGFL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09144
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47419
Sarcoma_SARC_TCGA-DX-A8BP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
abnormal metabolism	MPO Gene-Phenotype Associations	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73418
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02686
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29866
TE6	CCLE Cell Line Gene Expression Profiles	1.0	2.4082
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7075
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.44614
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
icSARS CoV_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.39924
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930402
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71094
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18607
FOXO1_KD_GDS2720_478_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.3439
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
Lung squamous cell carcinoma_LUSC_TCGA-68-A59J-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016643
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.681
A549_Rigosertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135817
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057749
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7969
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73248
XY body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.533
abnormal male reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79126
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.357
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
regulation of homologous chromosome segregation	GO Biological Process Annotations 2025	1.0	null
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05518
epithelial	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06989
NFIL3	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2002
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81187
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051996
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91428
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26084
germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299601
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836375
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18601
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04874
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.601
EN	CCLE Cell Line Gene Mutation Profiles	1.0	null
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.485
HDLM2	CCLE Cell Line Gene Mutation Profiles	1.0	null
Rpd3S/Clr6-CII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5717
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal testis size	MPO Gene-Phenotype Associations	1.0	null
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1647
TO175T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84393
A549_WHI-P154_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180763
PPARalpha_OE_GDS2289_244_mouse_Skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FLCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52863
PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26442
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21749
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82526
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88726
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4083
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048149
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65048
A549_Fluorouracil_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177122
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00749
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60224
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21952
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41464
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.07272
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
DNA gyrase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8697
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6022
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52911
Perturb_9515_KO_Sall4_ERP111723	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.03193
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34575
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Inner kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
arrest of male meiosis	MPO Gene-Phenotype Associations	1.0	null
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851847
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983409
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.442
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17635
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0358
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MutLgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.817
METTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84647
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nuclear chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB3A_Mutation - D77G point mutation_GDS2482_704_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852186
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1014
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51349
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10727
Teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.962
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6683
NEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11093
Piriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7062
A549_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187349
SUMO-targeted ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
chromosome organization involved in meiosis	GO Biological Process Annotations 2015	1.0	null
NCIH1437	CCLE Cell Line Gene CNV Profiles	1.0	1.99105
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.322
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06497
lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.956395
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18247
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
KLF15_Deficiency_GDS2687_649_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DUSP1_KO_GDS1606_773_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
chr1_150730890_TAACA_T_b38	GTEx eQTL 2025	1.0	1.62165
Perturb_5008_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.76536
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910803
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50J-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.161
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Rhp55-Rhp57 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.436
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71516
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26226
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.274
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08674
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.725
PMC6192992__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4628-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2618
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50547
Perturb_4607_KD_H2A.Z_SRP345495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.487
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20197
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-IL10_rescued_LPS_downregulated-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
APOD_OE_GDS3913_489_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-548ai	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.344207
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836327
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5515
LU65	CCLE Cell Line Gene Expression Profiles	1.0	1.49456
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
Perturb_5092_KO_Max_SRP078684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.9663
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
A549_Celecoxib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167547
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.687
ETFRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8002
MDAMB435S	CCLE Cell Line Gene Mutation Profiles	1.0	null
NCI-H3122	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arrest of spermatogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.735
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06385
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74395
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836343
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7407
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11914
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38736
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MutLalpha complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.925479
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8639
first	GeneRIF Biological Term Annotations	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
condensed nuclear chromosome	GO Cellular Component Annotations 2015	1.0	null
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5489
ISTMES2	CCLE Cell Line Gene Mutation Profiles	1.0	null
Somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.332
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13541
colo800	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
KYM1	CCLE Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71298
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31321
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05727
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12641
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Transmembrane actin-associated (TAN) line	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81011
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8033
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904805
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
Ornithine carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Basal cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
biological regulation	GO Biological Process Annotations 2015	1.0	null
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22623
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.35102
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916128
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06702
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.663149
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07479
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56611
NCI-H841	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
ZNF570	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58983
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
NCAPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13215
GTEX-S95S-0426-SM-4B64I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893007
MDST8	CCLE Cell Line Gene CNV Profiles	-1.0	-2.69139
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.225976
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07479
RELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51309
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13297
chromosome	GO Cellular Component Annotations 2015	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826338
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78938
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM63A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31952
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-2102Ep-Genes_deregulated_in_2102Ep_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09397
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01749
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.738854
abnormal male germ cell apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83835
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
PRR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22388
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F0-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19096
chr1_150739896_GTTC_G_b38	GTEx eQTL 2025	1.0	9.25237
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34277
decreased germ cell number	MPO Gene-Phenotype Associations	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040778
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1403
abnormal female reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
nuclear chromosome	GO Cellular Component Annotations 2015	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22654
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80292
NCI-H810	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
GSE193258,GSE193259_9_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_6_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
Perinucleolar compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
ILRUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15494
LRRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67598
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48473
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41258
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05053
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298011
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1595
ANKS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32524
17603561-STable1	GeneSigDB Published Gene Signatures	1.0	null
CYBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64775
nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156513
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03287
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04573
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46706
DAOY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57586
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.56031
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal male germ cell apoptosis	MPO Gene-Phenotype Associations	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0834
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35569
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.578833
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27817
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
organelle fission	GO Biological Process Annotations 2015	1.0	null
regulation of chromosome segregation	GO Biological Process Annotations 2025	1.0	null
ZNF517	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43137
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41312
HCC-1395 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
Set1C/COMPASS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66928
ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.347511
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.607
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74962
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.227
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23236
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05443
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70325
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
Lung adenocarcinoma_LUAD_TCGA-69-7764-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-29b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.200331
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Waist-hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94459
abnormal male reproductive gland morphology	MPO Gene-Phenotype Associations	1.0	null
Pollen aperture	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
regulation of cell division	GO Biological Process Annotations 2015	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888071
ECI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69768
Endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
occipito-temporal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14852
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992858
Mitotic spindle assembly checkpoint MAD1-MAD2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
hsa-miR-548m	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
DNA-binding HORMA	InterPro Predicted Protein Domain Annotations	1.0	null
other phenotype	MPO Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1317
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.9592
A549_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179407
Rectum adenocarcinoma_READ_TCGA-CI-6624-01C-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A427	DepMap CRISPR Gene Dependency	1.0	4.86159
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90482
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30561
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21329
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
organelle	GO Cellular Component Annotations 2015	1.0	null
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066295
cell-cycle-proteins	Phosphosite Textmining Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29573
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01566
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5160_KO_Mettl3_SRP048598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.38972
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13157
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZE-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC12096173-JCMM-29-e70318-s001.docx-5-AHCTF1_AHCTF1	Rummagene Transcription Factor Associations 2026	1.0	null
Caffeine consumption from coffee	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49194
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64979
MYOCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3963
failure of embryo implantation	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.900951
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	1.0	1.37719
reduced	GeneRIF Biological Term Annotations	1.0	null
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70926
NCIH1299	CCLE Cell Line Gene Expression Profiles	1.0	1.91061
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
beta-heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24947
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEIOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14226
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.369997
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989143
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.75812
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0229
hormad1	GeneRIF Biological Term Annotations	1.0	null
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43143
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8151
RGL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78106
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07375
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0223
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0218
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59983
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63124
ERAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47215
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33212
Sarcoma_SARC_TCGA-X6-A8C7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01259
SF126	CCLE Cell Line Gene CNV Profiles	-1.0	-2.78412
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8079
H9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
NDUFA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18045
heparin_homo sapiens_gpl570_gse12710	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mitotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.944
GSE212330_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.595593
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
Spermatoproteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
PMC8960869__F8	PFOCR Pathway Figure Associations 2024	1.0	null
U-698-M	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.07968
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984321
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00395
Gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54526
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7062
Buffy coat cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46184
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982882
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.615118
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.888639
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173571
layer 5 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5668
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61136
SOX2-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
AMO1	CCLE Cell Line Gene CNV Profiles	1.0	2.36424
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8956
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844523
all	GWASdb SNP-Phenotype Associations	1.0	0.028339
ECGI10	CCLE Cell Line Gene Expression Profiles	1.0	1.37663
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
abnormal cell morphology	MPO Gene-Phenotype Associations	1.0	null
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17109
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38895
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.201
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.191
chr1_150730558_CAGA_C_b38	GTEx eQTL 2025	1.0	2.6181
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
female gamete generation	GO Biological Process Annotations 2023	1.0	null
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.185
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62579
Rif1_KD_GDS4943_243_mouse_F1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
regulation of nuclear division	GO Biological Process Annotations 2015	1.0	null
BT12	DepMap CRISPR Gene Dependency	1.0	5.07891
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08267
abnormal DNA repair	MGI Mouse Phenotype Associations 2023	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
LK2	CCLE Cell Line Gene Expression Profiles	1.0	2.04435
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951612
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GM-06B-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51489
ITPKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62407
PMC9161725-Table_4.xlsx-EHF-CSAG1_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BL-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
postcentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19318
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.358
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.514
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98841
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.104
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54732
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15768
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
synapses	Phosphosite Textmining Biological Term Annotations	1.0	null
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29087
Calu-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.017
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75942
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
condensed chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
FOXO3_01_267	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.89297
small testis	MGI Mouse Phenotype Associations 2023	1.0	null
Primary somatosensory area, mouth, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43074
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.213621
DDIT4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59285
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20594
SOX2	ChEA Transcription Factor Targets	1.0	null
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13939
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79931
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61179
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287447
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54108
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.17
RNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28943
Non-Obstructive Azoospermia	DisGeNET Gene-Disease Associations	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nuclear membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.463
HCC1599	CCLE Cell Line Gene Expression Profiles	1.0	2.6549
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.427254
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09505
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12919
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2061
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65291
A549_Iniparib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125016
Immature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.452
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2042
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19673
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.48805
negative regulation of cell division	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5629-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
nuclear lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.655172
Right nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.865523
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85458
CTCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23693
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
MYCN	ChEA Transcription Factor Targets	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.81836
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1932
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866485
cell development	GO Biological Process Annotations 2015	1.0	null
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8959
blastocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219928
GSE179002_2_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDK19_knockdown_162_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.59464
Sarcoma_SARC_TCGA-X6-A8C2-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30642
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844089
CTDSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88443
OAW28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54275
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36212
population	GeneRIF Biological Term Annotations	1.0	null
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
PCI6A	DepMap CRISPR Gene Dependency	1.0	3.20282
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TULP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17944
Lung adenocarcinoma_LUAD_TCGA-05-4398-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal apoptosis	MPO Gene-Phenotype Associations	1.0	null
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hsa-miR-3607-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06869
decreased male germ cell number	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5853-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of homologous chromosome segregation	GO Biological Process Annotations 2023	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383509
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46573
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.870227
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30052
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05892
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7947
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840476
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17821
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899031
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56707
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.066
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05308
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	4.28721
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983409
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
MutLbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.192
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08859
NCI-H1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
A549_Mercaptopurine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117001
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
azoospermia	GeneRIF Biological Term Annotations	1.0	null
Leydig cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.639
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65687
GSE115542_2_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
abnormal sperm number	MPO Gene-Phenotype Associations	1.0	null
abnormal sex gland morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5246
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64839
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0731
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08306
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25226
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970245
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
ERBB2_druginhibition_7_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.66147
inactivation	Phosphosite Textmining Biological Term Annotations	1.0	null
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07254
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31418
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0315
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.90644
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91784
female infertility	MGI Mouse Phenotype Associations 2023	1.0	null
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.452
MIS12/MIND type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.141
DNAJB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99789
lateropallial prepiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57024
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12231
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43215
H1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72244
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3679
GSE226355,GSE226357_3_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64123
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15225
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041968
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07083
GSE179002_0_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.12
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70781
medial parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.86355
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.017
chromosome	GO Cellular Component Annotations 2023	1.0	null
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17159
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.038
hsa-miR-548t	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.52356
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995379
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72699
hsa-miR-3973	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95759
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8828
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
MutSalpha complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.929
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0694
RENT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25803
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2516
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.945931
GTEX-QDVN-1026-SM-48TZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.369
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09306
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955485
synaptonemal complex assembly	GO Biological Process Annotations 2015	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.017
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39674
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.870312
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.76
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58814
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13297
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3618
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.979771
Slx1-Slx4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17851
NLGN3_KD_GDS4759_336_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SGPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22587
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835388
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1545
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18003
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33692
Embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838764
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06009
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18864
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43293
nuclear part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
PMC5637904-PATH-243-193-s015.xlsx-human_up_in_ductal_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.017
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18441
Meiotic recombination initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.9
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3772
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04988
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08078
Perturb_66_OE_Zscan4_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.69928
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9783_KD_Tcf7l1_SRP321923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.09038
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.791
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81253
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58096
Brain Lower Grade Glioma_LGG_TCGA-HT-7681-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39326
spermatogenesis	GO Biological Process Annotations 2015	1.0	null
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
noa	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4724-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TXNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57442
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93209
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.91
A549_Selisistat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182003
Male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.324
PAX5_OE_GDS4978_547_human_L428	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55154
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.644
MCM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926828
atr	Phosphosite Textmining Biological Term Annotations	1.0	null
Meis2	MotifMap Predicted Transcription Factor Targets	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20678
hsa-miR-522	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
Lung squamous cell carcinoma_LUSC_TCGA-66-2770-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
DMD_Deficiency_GDS2996_614_mouse_Cardiac muscles from 10.5-month (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10688
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
DU-145	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IR-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-0940-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42931
PTEN_KD_GDS4759_337_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14449
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.452
Sarcoma_SARC_TCGA-SI-A71O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83066
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal chromosome pairing during meiosis	MPO Gene-Phenotype Associations	1.0	null
DMS-273	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.01987
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64534
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21155
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6851
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.397
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04417
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86952
EFNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83218
abnormal male germ cell morphology	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.896067
Perturb_5059_KD_Usp7_SRP235595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.7871
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51132
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
SLVL	DepMap CRISPR Gene Dependency	1.0	2.23408
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40243
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49698
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850885
FFAR4_KO_GDS4811_507_mouse_adipose	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67712
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904291
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932708
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27858
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.14831
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76364
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
although	GeneRIF Biological Term Annotations	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
A549_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156781
female gamete generation	GO Biological Process Annotations 2015	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34417
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_21-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_12849_KO_Rnf114_SRP301146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.453
protein-transport	Phosphosite Textmining Biological Term Annotations	1.0	null
embryonic stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.582019
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25826
abnormal male reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal chiasmata formation	MGI Mouse Phenotype Associations 2023	1.0	null
A549_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135466
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40198
F-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4743
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847457
oogenesis	GO Biological Process Annotations 2015	1.0	null
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28615
BCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73787
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24084
RSBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68709
TULP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00643
regulation of cell cycle	GO Biological Process Annotations 2015	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
SUDHL5	DepMap CRISPR Gene Dependency	1.0	4.0013
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33586
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.926
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44426
RPUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34398
teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.462016
Perturb_8757_OE_CCNE1_SRP314351	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.23186
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30478
TMEM80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26956
hsa-miR-29a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC5787431__F2	PFOCR Pathway Figure Associations 2024	1.0	null
mTert_OE_GDS1211_256_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965891
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sarcoma_SARC_TCGA-KF-A41W-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
A549_Busulfan_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157023
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Azoospermia	DisGeNET Gene-Disease Associations	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76735
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KMM1	CCLE Cell Line Gene Mutation Profiles	1.0	null
Oligospermia	DisGeNET Gene-Disease Associations	1.0	null
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22831
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.441
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76555
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42808
PJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24272
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59446
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66766
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.955565
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14556
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92948
Basolateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74719
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.956
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83906
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9683
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.61078
XRCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31217
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1291
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.46723
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00157
Early recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.638
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2259
ct96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Meiotic nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.46
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61137
ZNF501	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56112
synaptonemal complex organization	GO Biological Process Annotations 2023	1.0	null
ING2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35527
Left nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987142
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916691
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17717
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.658
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84338
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57024
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	1.0	2.23078
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456055
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59476
Mdr2_KO_GDS1990_285_mouse_Livers of 3 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68578
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6786
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20843
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00207
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.50857
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63095
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.205
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066795
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435289
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91495
USP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07256
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.324
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31499
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.3412
SCA1_Knock-in_GDS1756_233_mouse_Forebrain tissue - 4 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
negative regulation of cell cycle process	GO Biological Process Annotations 2015	1.0	null
abnormal internal male genitalia morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25387
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86141
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898637
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.711729
PBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32791
MDAMB436	CCLE Cell Line Gene Expression Profiles	1.0	1.45066
compared	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-596	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
NCIH526	DepMap CRISPR Gene Dependency	1.0	3.2398
Perturb_5009_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.44608
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.602
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55025
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77517
cellular process involved in reproduction in multicellular organism	GO Biological Process Annotations 2015	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962094
small gonad	MPO Gene-Phenotype Associations	1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889164
SP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27229
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28889
oogenesis	GO Biological Process Annotations 2023	1.0	null
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12275
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.138
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
hsa-miR-575	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	1.72704
PAX5	ENCODE Transcription Factor Targets	1.0	null
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14027
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884508
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35994
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07479
A549_Clevudine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202339
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2464
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRCA1-B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
PAX5_OE_GDS4978_548_human_L428-PAX5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33674
ZIC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12611
cell part	GO Cellular Component Annotations 2015	1.0	null
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60564
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.861
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
COLO792	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976938
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41001
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20946
malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.346042
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18537
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82255
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62969
A549_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182389
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66145
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16003
Perturb_4558_KD_Prmt5_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.73338
abnormal seminiferous tubule morphology	MPO Gene-Phenotype Associations	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
Perturb_5669_KD_Yy1_SRP281855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.9083
separase-securin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26753
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00113
nuclear part	GO Cellular Component Annotations 2015	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208481
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
negative regulation of organelle organization	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.74266
LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12938
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.920398
NCIH1734	CCLE Cell Line Gene Expression Profiles	1.0	1.40247
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41922
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05812
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10087
Ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.976
Sperm cytoplasmic droplet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
meiotic dna double-strand break formation	GO Biological Process Annotations 2015	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.79843
Replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.593
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78781
negative regulation of meiotic cell cycle	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.914254
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04924
A4FUK	CCLE Cell Line Gene CNV Profiles	1.0	2.08219
hsa-miR-3168	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
U2OS	DepMap CRISPR Gene Dependency	1.0	4.91358
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63828
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861961
hsa-miR-3591-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
VSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25278
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C3orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02789
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5085
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17799
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
Linear element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.768
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09097
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39213
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58483
GDPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6012
ELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76532
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	3.3215
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.017
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28478
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
FOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15006
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.749579
Perturb_4556_KD_Ncor2_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.72429
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
Obesity	DisGeNET Gene-Disease Associations	1.0	null
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.37547
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.11021
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05204
TET1	ChEA Transcription Factor Targets	1.0	null
EPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9123
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827972
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58387
ZBED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26123
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13388
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919094
MutSgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.13
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27663
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F3-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.919584
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49914
nucleus-vacuole junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13901
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910305
Holliday junction resolvase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15221
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35185
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43303
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93785
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052299
NCIH1703	DepMap CRISPR Gene Dependency	1.0	2.4532
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE3583	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.31667
Adenoid squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F1_KD_GDS4094_446_mouse_Mammary tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
A549_AZD1480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151195
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.575912
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43351
Exoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8881
meiotic cell cycle process	GO Biological Process Annotations 2015	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C18orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51912
SNU520	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993569
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skin	GTEx Tissue Gene Expression Profiles	1.0	0.959562
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30916
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03693
GK_KO_GDS1555_127_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50411
Lung squamous cell carcinoma_LUSC_TCGA-77-7140-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH650	CCLE Cell Line Gene Expression Profiles	1.0	1.34772
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918056
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74624
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.24808
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.74266
POU3F2	ChEA Transcription Factor Targets	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transcriptional	Phosphosite Textmining Biological Term Annotations	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19509
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mei2 nuclear dot complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08517
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946003
decreased testis weight	MPO Gene-Phenotype Associations	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.457606
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97213
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46465
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10878
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134