association	dataset	threshold value	standardized value
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
LILRB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00787495
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29501
BRD-K94647035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28446
KCNK9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533186
BRD-K45522895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39388
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07822
IGSF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00700922
TIMM23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619003
EGFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0031284
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37935
BRD-K31521981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26444
BRD-K05831864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11389
HEPG2	DepMap CRISPR Gene Dependency	1.0	2.98373
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BTNL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00793277
BRD-K74035204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05881
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17539
BRD-K57027644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20336
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZR751_BREAST	CCLE Cell Line Proteomics	1.0	4.60474
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-E2F1_UP_V1_UP-Gene_name_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
GSE156667_0_v_1_lrrc8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K29661539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04276
BRD-K95712112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09221
WNT7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060176
PPM1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20281
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COASY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00281426
EPHB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00686327
GH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0067894
BRD-K17751525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16796
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29778
SGPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664037
BRD-K10182289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69808
BRD-K20836550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12266
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_downregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
STRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04218
BRD-K00537235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00703
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2049
BRD-K35119180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62853
KRAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0044481
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00702585
BRD-K64451677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93691
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22308
BRD-K21747676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21842
BRD-K20447569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48633
NMUR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00683863
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PNP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00318598
SLC30A8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0072031
BRD-K52500055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01293
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.00817
BRD-K21386594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94783
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34942615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08043
TBCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00616079
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56973599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42579
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593728
BRD-K04771555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34761
BRD-A40504327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21731
SNU685	DepMap CRISPR Gene Dependency	1.0	2.94277
BRD-K88820027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82562
BRD-K43922968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25369
BRD-K73462370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00594
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.15414
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM20C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32723
BRD-K69491845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36428
regulation of protein modification process	GO Biological Process Annotations 2023	1.0	null
VWA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00456619
GRIK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073683
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35717699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58862
POLR2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626684
BRD-A46317335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68016
MS4A6E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603648
PSMA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657486
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFEC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518369
BRD-K27870441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68172
DNA repair	GO Biological Process Annotations 2023	1.0	null
VPS9D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667524
CHI3L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00738108
BRD-K11493601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54048
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64353470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60536
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26850845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0045
GSE89018_12_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35209334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70634
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.992169
GTEx Heart 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-3.1135
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06289
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IFIT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664744
WDHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0071276
BRD-K67261586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11286
NREP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641333
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	3.63285
NPTX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633423
DSCAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664739
STS-0421	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.96905
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00452
CES1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636214
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
S1PR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056688
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00691292
C4BPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00706564
STKLD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00712309
BRD-K39979888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78966
BRD-K84606053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10484
BRD-K97052218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22679
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49112
HCC1187	DepMap CRISPR Gene Dependency	1.0	7.88355
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	9.94843
TSPAN9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544857
BRD-K56775726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53221
BRD-K24669989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16328
AKR1D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00427018
BOLL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724612
TICAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00824165
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17420784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50101
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44344
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTPRJ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477058
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07689069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09667
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-E2F1_UP_V1_UP-Ensemble_gene_ID_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
SKMEL30_SKIN	CCLE Cell Line Proteomics	1.0	2.67446
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TYKNU	DepMap CRISPR Gene Dependency	1.0	2.77758
BRD-A84816049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34767
CHAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557948
OXER1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560921
BRD-K16862492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55259
FN3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00904307
BRD-K59120074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04521
APOBEC3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00712966
PMC11995938-74_129_TableS2.pdf-10-LIN54_LIN54	Rummagene Transcription Factor Associations 2026	1.0	null
SPTLC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619816
BRD-K95551067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59836
BRD-K30589514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12747
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69183
SLC22A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0068113
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34112
BRD-K37680172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62257
AP5B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541183
BRD-K38060656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00179
BRD-K38737333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75875
BRD-K27982554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50272
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of protein ADP-ribosylation	GO Biological Process Annotations 2023	1.0	null
ACADM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658276
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203158_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14780713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2842
MAX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00827966
CAMK1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552124
BRD-K80763723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86684
LC1SQ	DepMap CRISPR Gene Dependency	1.0	2.14997
BRD-K23585987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77403
BRD-K08658757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.055
RPS19BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08688
BRD-K64531863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01252
MYO3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523157
IL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524308
SYPL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00786447
SLC41A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523136
REEP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05389
HCC-78	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.79792
CASS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058369
GSE227634,GSE228381_0_v_7_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84457681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62859
BRD-K56441027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09806
BRD-K21544408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87464
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19588
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30335
BRD-A39506880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15944
BRD-K45571747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02223
MCM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536565
PMC12311696-ao5c02807_si_001.pdf-88-ZNF598_ZNF598	Rummagene Transcription Factor Associations 2026	1.0	null
YARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00387267
GSE165174,GSE165175_0_v_1_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BT549_BREAST	CCLE Cell Line Proteomics	1.0	2.72707
RSAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618511
BRD-K39649774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41129
OSBPL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599683
RPL37A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00746131
BRD-K23435841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.57992
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06272
RRP15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00719956
RPL23A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00921257
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29861
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30488928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04182
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COBLL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660695
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95854766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10935
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABCG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00602061
TAF6L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620402
BRD-K13370005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15244
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KNS81	DepMap CRISPR Gene Dependency	1.0	3.40058
CYP2S1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672638
PMC8410861-41467_2021_25544_MOESM32_ESM.xlsx-MCR-MCR_cells_-_DGE_iGCA_testis_vs_adult_testis_from_GSE112013_and_GSE124263_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
EML4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00423526
GSE200159_1_v_0_setd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07501326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27944
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD86	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531352
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28691459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07422
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14081852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17455
PDXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36826
BRD-K01853144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04044
PANC0403_PANCREAS	CCLE Cell Line Proteomics	1.0	10.7033
CSDC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00528978
JAZF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610412
LMCD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00677251
BRD-K02118124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08279
GSE165689_0_v_1_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ITGA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00815721
BRD-K64827406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70402
BRD-K19020285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5654
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66591
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21427
SIRT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499542
SLAMF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716541
BRD-K68732617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06126
BRD-K67979704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31141
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78789
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89101
KCNQ5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511229
BRD-K07802542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09531
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88864
GJB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513027
DCUN1D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00779663
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_ID_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH82	DepMap CRISPR Gene Dependency	1.0	3.16171
CX3CL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716096
DJM-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.99921
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32839286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17918
GSE211286_7_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
BRD-K60848736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68423
BRD-A57982699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16962
TDG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0074605
PPP6R3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00638488
BRD-K71132173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10954
BCL11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549741
BRD-K85919350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1026
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
SLITRK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00427571
BRD-A22502289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20531
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PKIA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062367
BRD-K63998843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17215
BRD-A54347351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35327
JMJD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00632634
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM67	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0103957
BRD-K89338336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75885
BRD-K90918886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20162
BRD-K32093012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2406
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SLC5A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538488
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BE2M17	DepMap CRISPR Gene Dependency	1.0	3.05903
CXXC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554
PTGER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00725643
BRD-K87412446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14502
BRD-K62935946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18297
BRD-K81372179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41774
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
ERRFI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00672809
BRD-K42605555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05363
TUBA1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706562
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36278
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33036
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM216	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633596
BRD-K49628278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11469
ELOVL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00581502
BRD-K11844807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19106
BBS9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0096775
VPS26C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00595099
BRD-K85474153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41822
DSCAML1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626432
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ADH1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560832
NB69	DepMap CRISPR Gene Dependency	1.0	3.14174
CELSR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573317
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34058
Cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
SNAI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685744
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17485
CCL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671291
RPS6KA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599487
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55728
BRD-K28814368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04545
KMT2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00682847
BRD-K07839394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35767
PDE11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0104524
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00798604
CPNE3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00310125
FERMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597543
STXBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00666235
BRD-K87268607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05655
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.919
UTS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00817109
XPO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00900193
ASCL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00799886
Oocyte_Embryo_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.919
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_TEAD2-gene_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-3.04983
INPP5D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00515667
BRD-K70856965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64276
BRD-K19755525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06064
BRD-K39179354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83177
GSE165174,GSE165175_0_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_Name_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
KP-4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.79139
BRD-K51743001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10053
BMX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00781283
BRD-K05222558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13605
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67525206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45152
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
increased red blood cell distribution width	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K38248920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74304
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
NLRP6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00697157
BRD-K11089039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09504
BRD-K60936953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82537
GSE192689_0_v_3_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10103
ZMYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30309
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32732
WM115	DepMap CRISPR Gene Dependency	1.0	2.90896
NMRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00448087
NCIH2170_LUNG	CCLE Cell Line Proteomics	1.0	5.10822
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78343
BRD-A38359809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14772
ABCA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640611
IL17D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00645889
BRD-K61168922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28198
BRD-K26051127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45531
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPAG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05491
BRD-K39223685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33179
PMC10082046-41467_2023_37049_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_Genes_upregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62294866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33355
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17303
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
STAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576599
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86065375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98601
B3GNT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00719131
BRD-K35123860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28055
ERGIC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00736861
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29755
BRD-K74598339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36603
BRD-K86111620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15433
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00729
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10618
BRD-K11247495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14289
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04485
BRD-K41655405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32539
BRD-A51381734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08468
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF391	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00625614
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
MITF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00787944
PRPS1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073141
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61776
HAPLN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583459
BRD-K72609226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91693
BRD-K30025024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96855
BRD-K28039328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88964
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TPST2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00845903
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66811
NME9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053783
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PATL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00617051
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.919
BRD-K59239787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54478
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00819584
BRD-K31939603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36973
BRD-K83845379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48451
BRD-K22606370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22945
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00577
SEMA3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00699308
BRD-K20497425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84152
BRD-K42385001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41612
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SULT1B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00940308
SEPHS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00865675
SLC23A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00613032
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A53381587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19612
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47917
BRD-K11812419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40187
BRD-K50201262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12515
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TNFSF13B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717709
PLD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637035
TSPAN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571814
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-PBX3-Unnamed_2_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13536
GSE167886_3_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GLUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85537
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
CD276	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654029
BRD-K60429174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10424
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15469
MS4A15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00720468
BRD-K77425312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39169
BRD-K60484506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05953
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
DPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39734
GSE255432_7_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46739745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59924
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
CD69	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0069301
IDH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694238
BRD-K18109695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17251
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CUEDC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00739416
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
LAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00799564
CLEC4M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615847
EIF2B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00822603
BRD-K78939372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01734
BRD-K16689648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0497
BRD-K54151058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4908
BRD-K12864860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98816
XBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00459795
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
BRD-K48557872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24589
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
double-strand break repair	GO Biological Process Annotations 2023	1.0	null
BRD-K15997423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45302
BRD-A40022950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07916
BRD-K14451397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34363
KYSE510_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.72008
INKA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055875
GSE206779_4_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87126326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47266
SBK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552935
ABI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0079108
ITGA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00756603
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RELL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00593781
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1038
MXD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00703845
BRD-K32916996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15035
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.93201
GSE81803,GSE81912_2_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11887
BRD-K50474387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49652
BRD-K23208879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30767
ANO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522956
BRD-K37865727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30129
BRD-K72467884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50974
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K99416393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36148
RGS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693479
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67194214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17233
BRD-K64055724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7153
CCSER1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530842
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72923
UQCRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060627
BRD-K86143816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49334
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIPOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00776423
PMC10679653-mmc2.xlsx-ISL1_KO_Markers_L-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
CYP27B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00876029
SPPL2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00813346
NALOXONAZINE-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19631
BRD-K51573654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74683
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671373
PMC9314667-Table_1.xlsx-Regulons-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37866276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00728
BRD-K99116119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06075
PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GLIPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512049
BRD-K75067815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33756
GSE231799_2_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP8B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0068467
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00604818
IMPDH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505208
PMC4067464-onc2013378x3.xls-Sheet1-Supplementary_Table_1_Top_1000_E2F4_Chip-Seq_targets_that_are_repressed_by_p53_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45904718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97149
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92468187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30341
LRRC32	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00638552
MCM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472861
BRD-K54112192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22054
ALPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00595394
GTPBP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563092
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05793
ARID4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00719425
BRD-K94378105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67532
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USP18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627403
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78017
SAMD4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00809
BRD-K04652643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45948
BRD-K71607378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05268
TMCO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618161
TNFRSF10D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540493
IL17F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616136
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32226
BRD-K32176914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24791
BRD-K55399138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57562
A172	DepMap CRISPR Gene Dependency	1.0	2.06839
GSE112860_9_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55867695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01557
GSE86507,GSE86509_7_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WEE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00672531
BRD-K14122415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39789
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
BRD-K73027631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.182
TRPC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509698
regulation of histone modification	GO Biological Process Annotations 2023	1.0	null
chromatin remodeling	GO Biological Process Annotations 2023	1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056395
BRD-K21582416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1032
ACAA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563158
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4788
NCIH226_LUNG	CCLE Cell Line Proteomics	1.0	2.0119
NCS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00688467
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52163
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01214
BRD-A17120244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25004
BRD-K26836050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23561
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PDE4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603409
RPL13A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054908
BRD-A31602150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10365
VSIG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533156
EW7	DepMap CRISPR Gene Dependency	1.0	6.59966
PARP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00329767
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
RPL15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00701302
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03916755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4769
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37219127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52335
BRD-K29254503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95193
BRD-K36474885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38624
BRD-K11687039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33702
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM47E-STBD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007371
PMC10960568-mjad044_supplemental_file.pdf-38-HES1_HES1	Rummagene Transcription Factor Associations 2026	1.0	null
JHUEM7	DepMap CRISPR Gene Dependency	1.0	3.63144
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15717
GRIN2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0083467
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26766324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58379
TMEM258	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484244
BRD-K79887921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43421
BRD-K05118861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50789
HT55	DepMap CRISPR Gene Dependency	1.0	3.19438
BRD-K97472167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05193
BRD-K22298558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6219
BAY-11-7085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48972
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PSMB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00326454
HAVCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00635288
IGSF23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00640975
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
RNASEH2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00708003
cyclothiazide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43087
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490015
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
BRD-K56650430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08016
BRD-K39027348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53347
PMC9810535-41590_2022_1370_MOESM3_ESM.xlsx-Table_S2-Table_S2-MECOM_network_genes_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
DNA repair-dependent chromatin remodeling	GO Biological Process Annotations 2023	1.0	null
BRD-A14098586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4586
BRD-K97562463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05292
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01597
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.570239
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05386
SYO1	DepMap CRISPR Gene Dependency	1.0	2.68392
BRD-K31526203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07073
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07939054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18924
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein ADP-ribosyltransferase-substrate adaptor activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K99220724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95435
GSE123022,GSE123030_2_v_6_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF2S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12935
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
CBR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00401162
BCAS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00812852
DOCK8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00862341
BRD-K19103068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01298
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23758
TIRAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600321
BRD-K10761381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0676
BRD-K26094217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00561
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14667
SPDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73145
TRIM	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01713
BRD-K75842461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77849
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100652_PCx_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07377
ATP5PB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496566
POLR3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005762
BCAN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00656276
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTTNBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00690903
ADRB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00476395
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NXPE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055645
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39625
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.17414
HPN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599343
FBXL19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535709
BRD-K75648723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35369
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53293966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12944
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38708
BRD-K47314501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75174
PSMA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0120313
BRD-K78162975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04447
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BSN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00634132
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15599
TRAPPC3L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520449
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26117128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5243
PFKFB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607283
POFUT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661159
BRD-K62460895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07445
BRD-K35617935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03422
ADGRA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00774728
BRD-K47217000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44673
BRD-K23316636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.163
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19493
OCILY19	DepMap CRISPR Gene Dependency	1.0	12.1103
BRD-A35931254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87401
BRD-K13488816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4701
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64257929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28049
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70386
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124375_13_v_12_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.919
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MFE296	DepMap CRISPR Gene Dependency	1.0	4.90947
KCNC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0087204
BRD-K89362730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42907
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PYGM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00723174
BRD-K32751688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26474
SQSTM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724672
BRD-K60578515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42676
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96438475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0926
BRD-K36515664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60374
GPR82	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573698
BRD-A67552019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23636
KIF18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3615
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A13983189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17039
BRD-K56041932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28978
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DCAF13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00655084
BRD-K32960568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21395
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.950176
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05522
PMC11364504-41388_2024_3115_MOESM2_ESM.pdf-28-HOXA10_HOXA10	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12640996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55041
BRD-A50287893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15255
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67090705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98733
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IL33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00829749
BRD-K50094173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03256
BRD-K24815102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65217
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72531838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06187
RHO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597438
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1206
TP53RK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059714
stress-induced childhood-onset neurodegeneration with variable ataxia and seizures	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
CAPN15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675543
BRD-K36170990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34586
BRD-K39087188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18514
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36129
PDGFRL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059984
SW626	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.29958
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
BRD-K81982648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40888
IL12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619937
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4021
BRD-K13567350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12165
BRD-K95678449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05509
HO1U1	DepMap CRISPR Gene Dependency	1.0	2.15996
PMC9314667-Table_1.xlsx-Regulons-ELF1_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
TBX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467406
CMPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569045
THEMIS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073806
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of transferase activity	GO Biological Process Annotations 2023	1.0	null
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69645
BRD-K67902591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26512
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CBX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00365061
BRD-K59188100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45067
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.98601
GPR55	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716369
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	3.24248
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05979
BRD-K47092271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25317
AGS_STOMACH	CCLE Cell Line Proteomics	1.0	3.44387
MS4A4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693875
CFD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460437
LAMTOR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00713057
BRD-K94115999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11077
BRD-K97939219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72803
BRD-K26479796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23128
FAM89B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00707507
ARMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19684
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GABRG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716855
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.766207
GSE212486,GSE212488_2_v_3_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TREML1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056765
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34822
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1573	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.63911
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83755051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10556
BRD-K17065706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06356
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47529
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
SW954	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.75259
BRD-K24418561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06049
BRD-K32118188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1179
BRD-K48615268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31344
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05327
BRD-K47658117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42904
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42814713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65198
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42536
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
BRD-K05015930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21539
BRD-K65005459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13036
BRD-K23326916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0545
BRD-K85821470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23801
TALL-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.25934
FAM13A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590426
BRD-K17120673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05847
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15046
RFTN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633757
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28524
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99726
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33347
BRD-K57202089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17738
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYP51A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00442459
CNTFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0063136
SLC47A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00754087
GPR18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00528586
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72085
BRD-K10241968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11389
PMC11630641-mmc8.xlsx-Human_1000cell_NOT_identified-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115283_1_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A73559168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27175
BRD-K02388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08117
BRD-K10221669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2281
BRD-K97682096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42815
SMARCA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00653437
BRD-K97829610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22446
GSE211177,GSE211178_4_v_10_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98153780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6404
MCHR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612455
SLC66A1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051187
ECE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00723866
BRD-K52416366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16389
NIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548684
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06937
CDC25A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00384317
BRD-K82509605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29164
FGF14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544802
PARPBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00609939
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26291
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIVEP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00481652
TOV21G	DepMap CRISPR Gene Dependency	1.0	2.08078
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85901675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6769
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP1B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00718464
BRD-K28276275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11429
GZMH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00646315
MTMR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27283
LARP4B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.007542
BRD-K81131499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45396
BRD-K92456318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56889
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
C2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620098
HRAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00437475
BRD-K35296094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02902
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3131
CR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507937
NXPE4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00830665
BRD-K26570871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69004
TMEM81	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00693815
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BLNK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488139
BRD-K71919612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33986
abnormal autopod morphology	MGI Mouse Phenotype Associations 2023	1.0	null
MAP3K3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00875868
COLO824	DepMap CRISPR Gene Dependency	1.0	3.7992
BRD-K26393435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00241
LBH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574117
BRD-K44692299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36578
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19045069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1586
BRD-A03764094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02925
IL18RAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575332
BRD-K84707727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06547
BRD-A76899420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36748
BRD-K52532740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79531
BRD-K76654183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08192
CXCL10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647333
BRD-K25805580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23552
CAL851_BREAST	CCLE Cell Line Proteomics	1.0	5.97771
BRD-K89935890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01627
BRD-K26976202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38507
BRD-K19142902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01043
GSE103372_0_v_3_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79303560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79838
BRD-K54224946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43465
BRD-K60719499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72216
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99859971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18074
HEXIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519198
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NTPCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00819618
LPIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639092
DAZL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524925
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
DNA damage response	GO Biological Process Annotations 2023	1.0	null
BRD-K27726368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67454
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01792
PMC4521181-oncsis201520x8.pdf-150-MTERFD3_MTERF2	Rummagene Transcription Factor Associations 2026	1.0	null
S100Z	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00502897
JUN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00455091
WAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00500362
BRD-K15444511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48321
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.03016
PMC13127299-mmc2.xlsx-PBX1_kdRNAseq-hgnc_symbol_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
CD226	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558504
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LS	DepMap CRISPR Gene Dependency	1.0	3.34424
CDKL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565108
BRD-K99447506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09493
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.919
CLIC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0066621
IL1RAPL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.010182
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11732233-mmc1.pdf-336-TCF3_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
PLEKHO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00634746
BRD-K13839731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42643
NB6	DepMap CRISPR Gene Dependency	1.0	11.2062
HEPACAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586255
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00446058
BRD-K16468319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30555
BRD-K74173779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14399
TM9SF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00439509
TGBC11TKB	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.11857
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
TNFSF14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00642369
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06784
BRD-K87082948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13106
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	3.26384
CISD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00462738
ABCC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073721
ZNF184	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00449092
BRD-K27026825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11199
BRD-K59544784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1397
BRD-K76661445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34801
TSC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00849027
BRD-K28923989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05445
DUOXA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608745
BRD-K36241360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31018
BRD-K86008496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5092
CADM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608522
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AQP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00697704
BRD-K54036439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59722
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05232
BRD-K21547369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0068
SLC22A18AS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062565
GNG11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596789
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16426
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
GBA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580329
KDELR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063439
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.68133
BRD-K50036850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52169
BRD-K41729242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33395
NMRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583012
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11843
CELSR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519205
CYB5R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585514
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
DNA metabolic process	GO Biological Process Annotations 2023	1.0	null
BRD-K24017250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01847
BRD-K31851055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04248
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33413
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14725
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64072266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08548
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
CYTH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25375
BRD-K31805261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41099
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOZ	DepMap CRISPR Gene Dependency	1.0	3.08742
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.02779
ES4	DepMap CRISPR Gene Dependency	1.0	2.38813
BRD-K38932508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26859
ADGRG5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00761559
CEP170	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00739676
BRD-K05777604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30389
HVCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512372
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKAR2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056344
IRF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619549
BRD-K92457070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10832
BRD-K26559753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38816
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BTN2A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00653475
BRD-K54079231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7022
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69668461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0585
BRD-K23361743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57277
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95864593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12809
APOB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049595
TCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596706
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
increased red blood cell distribution width	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K35001076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74369
BRD-K95251122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26938
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36718828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06226
BRD-K45928581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01832
ALG13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00655193
SYNGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591787
SPHK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647838
TMEM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75856
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28700379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36492
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46897949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91681
BRD-K34482448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08681
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KIF11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561224
BRD-K22093970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1079
BRD-A34492468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79385
BRD-K37763427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04485
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MICALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13991
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03237
LEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00688965
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
THRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.007096
OAS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073127
BRD-K35780971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04068
BRD-K41322154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00764
BRD-K78873216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62592
RTP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542884
BRD-K78574327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30308
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
nucleus	GO Cellular Component Annotations 2023	1.0	null
BRD-K98578493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00008
BRD-K15433418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3086
IFIT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576915
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28358
BRD-K64111129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48442
BRD-K17078647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11011
P2URK562	DepMap CRISPR Gene Dependency	1.0	2.04821
GSE148066,GSE157787_0_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47109712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11825
BRD-K89328601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97642
DUOXA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00869329
GSE255680_1_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DYRK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00776173
BRD-K83752863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25294
BRD-K25658788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34809
SCH	DepMap CRISPR Gene Dependency	1.0	2.7843
BRD-K39090122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83735
BRD-K67771738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72268
BRD-K07160586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39099
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02734
BRD-A22089150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86484
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CYBA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00604546
BRD-K33044659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79595
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
KCNK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627681
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24908
GSE89018_11_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08851
BRD-K30761927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62732
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41409
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88224221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08863
BRD-K28813194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95919
BRD-K95672449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15591
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRR5L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00785824
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
TO14	DepMap CRISPR Gene Dependency	1.0	2.76461
BRD-K97247086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81544
BRD-K38977317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59976
MG63	DepMap CRISPR Gene Dependency	1.0	2.17532
PDGFRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659001
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K81568980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21741
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24343201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72637
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19467
BRD-K46412655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17792
BRD-K24167233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50198
SYNM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051545
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SEC22C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14541
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35561
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35991
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6197
BRD-K80807286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0192
BRD-K24499562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68023
BRD-K13164804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21249
BRD-K78789413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19322
SNUPN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591307
BRD-K39965317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01836
BRD-K36523261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02358
SLC18A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521275
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16138
BTNL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605157
BRD-K43271856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07653
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00789
PIFO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33099
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55855103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08055
KRT19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0065518
POLR3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00364637
BICR22_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	2.30057
CCNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474985
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2058
CXCL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006157
HADHA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651013
EoL-1-cell	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.51538
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GLRA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628277
KPNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00854291
GSE221955_3_v_2_igfbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14399036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07663
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
Diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
BRD-K81751970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15257
CEACAM18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00668852
BRD-K12343830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15481
ZNF512	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00454892
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28294686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3137
abnormal autopod morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248045,GSE248046_4_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69349031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30844
BRD-K68617666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21782
GRB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051656
LRRC37A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00863584
BRD-K24599650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09533
INTS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589279
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21085
BRD-A69786436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48368
EZH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536128
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
RNPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7555
BRD-K10987837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58187
BRD-K49903196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13463
CSMD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0050044
PMC11949941-DataSheet1.pdf-44-GCM2_GCM2	Rummagene Transcription Factor Associations 2026	1.0	null
XRN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00817879
BRD-K00048792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13517
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
METAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00339846
BRD-K38557431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17874
ROS50	DepMap CRISPR Gene Dependency	1.0	4.7615
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
BRD-K83670600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23732
BRD-A16827030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26195
TNIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00961826
BRD-K22139757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38273
BRD-K00209945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03057
BRD-K13681383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51612
PRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00649013
CELSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62219
BRD-K38519440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51233
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.68151
SYM-2206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21383
ZGLP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619751
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05446
BRD-K22039769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07937
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34181077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.194
EIF2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25048
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83013052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32281
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07983
CCDC88A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20415
BRD-K39913853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14297
BRD-A79316179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5564
LYVE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00730366
NPSR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508095
U2904	DepMap CRISPR Gene Dependency	1.0	4.67588
DSG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00868092
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D2REFED4h_641_AR-D-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IL7R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00624149
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
CIB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00698886
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4515549-NIHMS63168-supplement-3.xlsx-1B_HNF4A-reg_genes_post-treat-GeneSymbol_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38434557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38885
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15282
BRD-K80877725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03722
ID4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00761543
GSE255680_2_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYP11B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603257
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ITPRIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057869
BRD-K09598619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30507
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
BRD-K58070604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25413
SMG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00700363
RPS27A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00896154
IL1RN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614014
BRD-K34369474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20793
UCK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526259
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82483
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
BRD-K18856772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0917
TKFC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00688939
BRD-K64567083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46687
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35651
IFITM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00740606
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21996934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75489
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22907
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTPN14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608258
LAMP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644031
BRD-K25649458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32231
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52007
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.46193
ICOSLG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00736844
BRD-K85112460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28805
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13199
BRD-K31936306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36829
BRD-K90047132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42782
RHOU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685035
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
CD1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0083949
EIF4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00841066
BRD-K17686226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03679
COL4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00890409
BRD-K69348766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19418
BRD-K44126416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01839
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37445
NB1643	DepMap CRISPR Gene Dependency	1.0	4.74386