association	dataset	threshold value	standardized value
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829184
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
Rb-E2F complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K23001296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04082
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52976
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.532701
regulation of release of cytochrome c from mitochondria	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3167	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-XUJ4-2126-SM-4BOOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
central	GeneRIF Biological Term Annotations	1.0	null
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40307
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.153
GSS	CCLE Cell Line Gene Expression Profiles	1.0	1.65854
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070417
pimethixene-7426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of mitochondrion organization	GO Biological Process Annotations 2015	1.0	null
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89511
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.632629
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16346
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pharyngeal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	2.15981
BCL2	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K90316899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27514
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18113
Lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.812
PMC8755726-42003_2021_2958_MOESM6_ESM.xlsx-489_corr_genes_TWIST1_signature-Gene_name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40782
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE181431_0_v_1_calr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71093375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26786
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0307
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42252
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.591392
Hodgkin's lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
Perturb_5242_KD_Eif4a2_SRP261876	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.0154
PMC9377669-tx1c00392_si_002.xlsx-TSA-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836935
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thioguanosine-4989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Thrombocytopenia	CTD Gene-Disease Associations	1.0	1.24275
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19161
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97888
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21973
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212553
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.6001
Lymphoma, Non-Hodgkin	HuGE Navigator Gene-Phenotype Associations	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
NA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
NOSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21497
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K87053028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78843
MIN6-N8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
positive regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39093
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055674
GSE198036,GSE198041_0_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20943
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54721
BRD-K46033477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14277
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
RI1	CCLE Cell Line Gene Expression Profiles	1.0	1.43416
BRD-K29726765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26876
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317545
KM12	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27685
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893059
B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.142
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36491
ZNF385B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31197
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33333
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DOHH-2	GDSC Cell Line Gene Expression Profiles	1.0	1.53195
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.835514
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35091
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	1.59389
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
U-266 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
PMC6488738-mmc6.xlsx-TCF12-Target_Gene_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00676
BRD-K13873561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82551
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ELF1	ChEA Transcription Factor Targets	1.0	null
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.7293
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K82217056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09784
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.02952
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59939
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKMEL5	Achilles Cell Line Gene Essentiality Profiles	1.0	1.06003
Edema	CTD Gene-Disease Associations	1.0	1.46251
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04391
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35513
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.982032
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269191
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ahrmediated	GeneRIF Biological Term Annotations	1.0	null
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29178
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30166
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56552
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51196703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63967
BRD-K37015376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35625
BRD-K83436911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56359
Exocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.96895
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050759
huh-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.527534
E2F4	ChEA Transcription Factor Targets	1.0	null
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03242
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232599
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03574
Lung squamous cell carcinoma_LUSC_TCGA-39-5029-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A375	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47045
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886233
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6041399__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45519638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90424
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.05233
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-1726-SM-4LVM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
WB-17-DI74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239505
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163938
NMB	DepMap CRISPR Gene Dependency	1.0	2.10108
Follicular lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
MG-262-7063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.91732
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
WC-33-YP46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216744
WM-115	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52594
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22719
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433374
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217974
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13226
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31981
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24085
MDAMB453	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.34102
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.387561
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PIK3CD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23171
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.892063
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2463
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4599
GSE180525,GSE180528_2_v_3_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.885129
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
PMC6488738-mmc6.xlsx-HLF-Target_Gene_HLF	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94979
hypoglossal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.569222
Perturb_14988_KO_Phf8_SRP093797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.60818
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02852
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-24-AT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.427294
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65096
YY1	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26837
hsa-miR-498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2882
AC-49-NG46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284443
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
modulator	GeneRIF Biological Term Annotations	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LS411N	Achilles Cell Line Gene Essentiality Profiles	1.0	1.13867
FL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826396
ZIC5_01_285	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.18833
BRD-K34209560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72036
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.64079
drofenine-3455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whose	GeneRIF Biological Term Annotations	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34425
Cycloplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
opm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
BRD-K59221664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56235
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.4678
Hippocampal subfield CA4 volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.3699
RKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25177
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1664
regulation of cell death	GO Biological Process Annotations 2015	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56475
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18082
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892232
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARA deltaORF6_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.16558
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04388
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66322
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.6947
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42052
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0238
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.61285
region	GeneRIF Biological Term Annotations	1.0	null
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C1QBP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE176305_0_v_1_rotenone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S5-Supplemental_Table_S5_Differentially_expressed_genes_between_cases_with_CM-induced_pY-STAT3_DMFI_1_76_STAT3_Low_v_DMFI_1_76_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
BRD-K26786741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26024
GSE179138_4_v_1_lama4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1315
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88763
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.898
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.81808
BRD-K76645599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02671
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75437
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94929
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043777
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	0.966316
GSE103003_1_v_0_zeb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.71296
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Isoamylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
SKOV3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.73624
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79383
B-lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.456319
multiple myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135654
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Plastid envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
Diffuse large B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
DC-22-OP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25176
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50257
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932727
Kidney Chromophobe_KICH_TCGA-KN-8422-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
Choline	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.837875
BRD-A66025870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89658
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
Hippocampal subfield CA1 volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.71549
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87259
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.589
RT-112	GDSC Cell Line Gene Expression Profiles	-1.0	-1.73926
PMC12436161-41388_2025_3507_MOESM1_ESM.pdf-13-TBX2_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.31069
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.680248
promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214765
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55827
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.781373
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32478
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ATF3_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31884
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.932445
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058375
BRD-K97256018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37846
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65359
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
BRD-K47474571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02795
respiratory epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109916
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371994
PMC7775270__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DC-17-ZB19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251118
BRD-K46562329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00157
AA-62-HP31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225632
Mantle cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE216043_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1715
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A94885304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87332
Chronic lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.084
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02709
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76157
BRD-K12385780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43295
NACC1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.900106
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01376
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43199
OVSAHO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08904
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
p53	GeneRIF Biological Term Annotations	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902521
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.393001
Perturb_16522_KD_ASXL3_SRP247927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Antler	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
icSARS CoV_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.10853
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36807
GTEX-OXRN-1426-SM-3LK5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853663
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
caspase3	GeneRIF Biological Term Annotations	1.0	null
SUZ12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60076175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19843
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67041
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.571745
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.46648
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235167
LS	DepMap CRISPR Gene Dependency	1.0	2.10906
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66605
AURKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060559
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74988
JURKAT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01239
OV-2008 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3869
Acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.822
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06897
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344449
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
derived	GeneRIF Biological Term Annotations	1.0	null
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98574
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GE-40-GQ38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.433841
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
BRD-K66288362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00755
LIVF001-022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49049
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064548
tamoxifen_homo sapiens_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CARD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05884
BRD-K46308702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52365
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K68087668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20828
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471927
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Activator of apoptosis harakiri	InterPro Predicted Protein Domain Annotations	1.0	null
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31225
pimasertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30652
anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059537
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.972
proadifen-7165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary Central Nervous System Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K18978449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6701
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52537
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875241
cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132991
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64751430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51057
SAOS-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.816068
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Multiple myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
Perturb_13928_OE_DLG2_ERP119345	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21151
PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estrogen-receptor positive breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.294772
GSE176305_0_v_3_rotenone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977359
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02872
plasma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129172
lymphomas	GeneRIF Biological Term Annotations	1.0	null
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47955
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GA-81-DL34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.414981
BRD-K86855109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44748
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967305
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3536
Bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
MOLT-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.36677
Perturb_9659_KD_SOX11_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5034
Mitochondrial permeability transition pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.457
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LIN28B_01_153	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62261
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07203
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58382
PMC5856858__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0373
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26435104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72562
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068783
GSU	DepMap CRISPR Gene Dependency	1.0	2.16143
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58148
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3084
PMC7432812__F2	PFOCR Pathway Figure Associations 2024	1.0	null
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30021
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CB-25-VR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250384
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.245451
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.285138
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37534
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13707
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE93918_2_v_3_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8750516__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Hepatic Encephalopathy	CTD Gene-Disease Associations	1.0	1.10175
Status Epilepticus	CTD Gene-Disease Associations	1.0	1.13997
palmitateinduced	GeneRIF Biological Term Annotations	1.0	null
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059632
19808871-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC7674767__F1	PFOCR Pathway Figure Associations 2024	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270561
PMC8836072__F3	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K55855103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12176
BRD-K71415389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86572
HCC1395	DepMap CRISPR Gene Dependency	1.0	2.12847
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.28555
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21269
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.985343
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hmc1	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7356
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20388
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04411
Amyloplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
Learning Disorders	CTD Gene-Disease Associations	1.0	1.70574
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160387
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233457
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081965
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832193
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.624927
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.949147
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
PMC9023794__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K82504878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52383
GSE77005_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925024
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	1.06061
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930961
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
Xylanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
GSE153757,GSE153758_0_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918345
PMC8601427-pone.0259197.s005.xlsx-upstream_TFs-ETS1_target_genes_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Atrovastatin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.982
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73453
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291718
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HBL-100 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
DJ-1_KD_GDS3750_373_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Dizziness	CTD Gene-Disease Associations	1.0	1.55698
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
19893615-Table5	GeneSigDB Published Gene Signatures	1.0	null
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
execution	GeneRIF Biological Term Annotations	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892812
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059155
BRD-K88274759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97309
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
TP53-20018659-R1E-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.67821
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4171_KO_Banf1_SRP302680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.2108
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11616
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.368998
PMC12125372-41423_2025_1290_MOESM1_ESM.pdf-5-ATF4_pathway_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34927
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
component	GeneRIF Biological Term Annotations	1.0	null
GSE246576,GSE246826_0_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BLZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18371
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19001
positive regulation of cellular component biogenesis	GO Biological Process Annotations 2025	1.0	null
BRD-K87951090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67487
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	0.875141
PMC5530849__F4	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K19764912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54607
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53387
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17898
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Npas4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.8272
Perturb_11152_OE_Myc_SRP048459	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.84376
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9310348__F1	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83825
PMC10136030__F2	PFOCR Pathway Figure Associations 2024	1.0	null
mdamb415	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873278
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79059
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22637
KMS20	CCLE Cell Line Gene CNV Profiles	1.0	1.40189
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424581
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52734
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
after	GeneRIF Biological Term Annotations	1.0	null
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08374
congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142474
nerve	GeneRIF Biological Term Annotations	1.0	null
BRD-K86600397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35446
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_6_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF4alpha_DEPLETION_GDS4798_91_human_HepG2 hepatocellular carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC3844829__F3	PFOCR Pathway Figure Associations 2023	1.0	null
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K33480200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55882
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2857
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899765
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.0074
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27917
Oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00676
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16882
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17305
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12399715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22178
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
WiDr cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829184
Presubiculum volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
PMC2712786__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90521
gossypol-4762	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05686
PMC6890986__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
stomach	HPA Tissue Protein Expression Profiles	-1.0	-1.00332
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE193588_1_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
propose	GeneRIF Biological Term Annotations	1.0	null
inner CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15319
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47768
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42Q-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60806315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36797
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847056
BRD-K83673542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28662
BRD-K35588268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55251
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Colonic adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18554
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.41085
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4018
BRD-K32018176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21004
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.191
Diffuse large B-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
MM1S	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07476
PMC7411521__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	2.09545
IMR-32 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
mutants	GeneRIF Biological Term Annotations	1.0	null
Spear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
Anemia	CTD Gene-Disease Associations	1.0	1.42696
dhd/k12/trb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.553491
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.346409
BRD-K65488906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03795
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inhibitors	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-468 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85639
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
S0-EE-YEKU_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217128
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23382
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875201
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fragmenting	GeneRIF Biological Term Annotations	1.0	null
BRD-K30682979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54571
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.544
astrocytic	GeneRIF Biological Term Annotations	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bergapten	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85102
Perturb_11553_OE_SIRT6_SRP394380	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.42697
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.917864
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
PMC7225374__F11	PFOCR Pathway Figure Associations 2023	1.0	null
NALM-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.876736
BRD-K56890200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68186
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
ut1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
GSE187005_5_v_2_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8616957-41467_2021_27270_MOESM4_ESM.xlsx-Sheet1-Supplementary_Data_1_Differentially_expressed_genes_FDR_0_05_edgeR_exact_test_in_MLL-AF4_infant-ALL_vs_MLL-AF4_childhood-ALL_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83186
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19048
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836935
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00676
transactivated	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-DX-A6BH-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3-27146783-CHIP-SEQ-COLON-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
18318837-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.28294
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.866888
mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424963
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67391
Perturb_16888_OE_Sca17_SRP248035	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.17843
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.211934
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64208
Seizures	CTD Gene-Disease Associations	1.0	1.7185
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80996561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03783
PMC4563120__F5	PFOCR Pathway Figure Associations 2023	1.0	null
MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12969
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCI-AML2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10163
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30695
CBX3	ENCODE Transcription Factor Targets	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
JD-62-TK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.495353
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22246
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
D458	DepMap CRISPR Gene Dependency	1.0	2.0502
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918248
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40351
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.177029
BRD-K07486034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10748
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-13_CD7_CD1a_DEG-DEG_L2FC_1_0_FDR_0_05_REL	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hepatitis	CTD Gene-Disease Associations	1.0	1.30421
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37288
CTB-1	GDSC Cell Line Gene Expression Profiles	1.0	2.35617
PMC7531772__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G3-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A463-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1287	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE160373_1_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60521891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42148
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14825
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50935
central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064447
positive regulation of cell death	GO Biological Process Annotations 2015	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.507657
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.20687
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958851
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064207
FLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02314
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K99581286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74554
FAM8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49283
modulating	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4439078__F5	PFOCR Pathway Figure Associations 2024	1.0	null
alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.281153
BCL2L2-PABPN1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88964321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54512
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876214
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
dream	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97835
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.50942
BRD-K67626097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62164
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSK3A_knockdown_207_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52575
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.907793
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.444188
bcl-2 family protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.524704
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
b-lymphoblastoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.00332
T-98G cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inactivated	GeneRIF Biological Term Annotations	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nasopharynx carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3356
positive regulation of mitochondrion organization	GO Biological Process Annotations 2023	1.0	null
BRD-K11752384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21609
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931379
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38415
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8628
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70929
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849498
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.525
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956154
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC10158025-ijbsv19p2081s6.xlsx-SupTable5-ZBTB20_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.50955
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GE-29-ZM45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256166
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
works	GeneRIF Biological Term Annotations	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Levothyrox-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52983
Perturb_1179_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.39517
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62739
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-34-KW62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289391
JARID2-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
apoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.171937
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5258
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20766
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875856
PMC8096095__F5	PFOCR Pathway Figure Associations 2024	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	-1.0	-1.00332
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4437475-mmc1.pdf-4-GCM1_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37989903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60198
BRD-K29111485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17029
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BF-02-AC35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.546352
SK-N-FI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
GSU	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
possess	GeneRIF Biological Term Annotations	1.0	null
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07778
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32208085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28321
Fatty Liver	CTD Gene-Disease Associations	1.0	1.91317
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30523
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39555
cancers	GeneRIF Biological Term Annotations	1.0	null
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9314667-Table_1.xlsx-Regulons-SOX10_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967379
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02346
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.6774
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888231
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19132
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917315
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
b-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
ccrfhsb2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07061
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.46766
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	1.69518
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31643
keratinocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373118
Kidney Diseases	CTD Gene-Disease Associations	1.0	2.0154
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11673
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71649
biological_process	GO Biological Process Annotations 2015	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50324
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.02
KA-63-FH23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372224
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79833
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881201
LB-65-SM65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284375
nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.223509
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.080051
MDAMB436	DepMap CRISPR Gene Dependency	1.0	2.02425
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EA-62-MI89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214042
NB13	DepMap CRISPR Gene Dependency	1.0	2.30289
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.46587
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10418
karpas45	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34534297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3851
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1091
Hippocampal volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.4699
JF-62-LU77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.400114
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54359
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.635
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05164
CBX8	ENCODE Transcription Factor Targets	1.0	null
Contagious pustular dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19461
496100521_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13193
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0408
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977359
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919623
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
DDX46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14252
terfenadine-6823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.1979
Perturb_17917_KO_Shank2_SRP314506	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.94321
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64556
BRD-K67096634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51394
BRD-K89116076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17839
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
PMC2533023__F5	PFOCR Pathway Figure Associations 2023	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343755
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.398
Apoptosis modulation and signaling	WikiPathways Pathways 2024	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55044152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13515
hypoxia	GeneRIF Biological Term Annotations	1.0	null
leukemia	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Renal Insufficiency	CTD Gene-Disease Associations	1.0	1.28672
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.575078
GSE198036,GSE198041_4_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19185848-TableS1	GeneSigDB Published Gene Signatures	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03921
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
psa1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.561
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.40505
tumors	GeneRIF Biological Term Annotations	1.0	null
tauopathy	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.21777
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8000576__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4572
BRD-A55722685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37348
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1105
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829625
Muscular Diseases	CTD Gene-Disease Associations	1.0	1.24401
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891959
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36135
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.35411
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_01_184	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65812
ZNF281	ChEA Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.06008
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26927
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4668
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	1.68452
BRD-K15694916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70572
CRCGN012_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14651
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.53159
BRD-K42789863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14828
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03311
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
BRD-K39961819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01824
Perturb_15286_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.90827
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38954
PMC4960540-srep30217-s5.xls-VD_metabolism-V_VDR_Q3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
clemizole-7371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
WRAP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67093
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4054
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.627761
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
KURAMOCHI	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02603
BRD-K12120581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14006
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38096
PMC12146336-Data_Sheet_1.pdf-13-ENSG00000101883_RHOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393442
AE-52-NW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246049
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.612471
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10534007-Table_2.xlsx-S5_unique_up_MSC_B-721_elements_included_exclusively_in_BFTC905_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal superior cervical ganglion morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963892
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZM-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2264
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.846668
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00728
BRD-K24205443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07319
CHOP-ATF4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
Dyspnea	CTD Gene-Disease Associations	1.0	1.40732
BRD-K31330911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23463
Central nervous system lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876953
BRD-K42435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0775
Myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.642
SKNAS	CCLE Cell Line Gene CNV Profiles	1.0	1.53153
ccd16lu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
deferoxamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59556
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased neuron apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HME1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943262
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7368-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31614
Infertility, Male	CTD Gene-Disease Associations	1.0	1.56656
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298011
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25103635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48679
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
SK-N-BE(2) cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846323
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
how	GeneRIF Biological Term Annotations	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06513
WSU-DLCL2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47085
Central nervous system hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22747
Perturb_6668_KO_FGFR1/FGFR3/FGFR4_SRP386785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.131112
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.89884
Weight Loss	CTD Gene-Disease Associations	1.0	2.00083
15691381-Table5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
peripheral t-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.128371
positive regulation of protein complex assembly	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47083242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41939
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947623
BRD-K98140933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01919
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9552
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052866
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10513366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54609
BRD-K59571728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42273
PMC9377669-tx1c00392_si_002.xlsx-MethylMerc-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18929
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K28483134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34053
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27082
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.598566
Dried cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12455
PMC3238295__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40565784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68349
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1638
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4B-Supplemental_Table_S4B_Differentially_expressed_genes_upon_ZFX_Knock_down_in_MCF-7_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1650	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27469
Pneumonia	CTD Gene-Disease Associations	1.0	1.05237
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111443
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PaCa-44 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
Hypospadias	CTD Gene-Disease Associations	1.0	1.07093
suz12	GeneRIF Biological Term Annotations	1.0	null
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29585
TE9	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05387
BEX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49375
aging	GAD High Level Gene-Disease Associations	1.0	0.295739
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.457
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3Y4-01A-51R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84158675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14485
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Apical plasma membrane urothelial plaque	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
principally	GeneRIF Biological Term Annotations	1.0	null
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078207
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83992
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.447308
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208922
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
promethazine-6717	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965117
BRD-K91879432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7926
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7734
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chronic gonococcal salpingitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12818133-mmc1.pdf-10-MAFB_MAFB	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.78
delsoline-5858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28604
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243198
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Thymic medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10868
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GSE85874_4_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831433
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0675
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
Apoptosis(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7499
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrial envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.349484
BRD-K65663356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53552
PMC4605373__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Mature stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96708
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.755783
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
PMC9377669-tx1c00392_si_002.xlsx-Carbamazepin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.86627
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PRMT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97655
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06874
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
ZFAND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28095
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955203
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11758
Lung squamous cell carcinoma_LUSC_TCGA-60-2707-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20165955-Table2	GeneSigDB Published Gene Signatures	1.0	null
Epipodite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.32212
SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.26198
Fibrosis	CTD Gene-Disease Associations	1.0	1.31536
JM1	CCLE Cell Line Gene Expression Profiles	1.0	2.56904
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71861
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-1026-SM-46MUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56968
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.511112
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2326
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01519
TMEM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.34932
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
ins-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.561644
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.298
AE-88-WQ63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220527
Acute myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.686
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33386
PMC9377669-tx1c00392_si_002.xlsx-Dextrometh-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal superior cervical ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877028
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.49457
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201901
BRD-K87264606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67087
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966121
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14082
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Endoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.473
dementia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6084
glioblastoma multiforme	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.450324
Apoptosis	KEGG Pathways 2026	1.0	null
PMC5543083-41467_2017_268_MOESM5_ESM.xlsx-Topological_properties_of_nodes-Supplementary_Data_4_Topological_properties_of_the_nodes_present_in_E2F1_interaction_map_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55037
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944484
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01665
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43414
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40023
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
gingival cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.775249
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00157
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2432
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10391
interacting	GeneRIF Biological Term Annotations	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58703
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89061
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5700962__F11	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K07484899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00657
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Supplementary_Table_2C_Contrast_ATF4-def_DMSO_8h_vs_HCT116_DMSO_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Subcortical brain region volumes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974204
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37956
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11318
BRD-K90444258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08622
LY-294002-996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17680_KO_Foxo1_SRP063560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.3279
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6284_OE_CPEB3_SRP364591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40377
fallopian tube disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.688692
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25214
BRD-K68008192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15106
CTCFL	ENCODE Transcription Factor Targets	1.0	null
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC5728441__F1	PFOCR Pathway Figure Associations 2023	1.0	null
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889432
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-148	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59018
positive regulation of cellular component organization	GO Biological Process Annotations 2023	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TP53-20018659-R1E-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15819_KO_PINK1_SRP343083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.73491
B-lymphoblastic leukemia/lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
Hippocampal subfield CA3 volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4699
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.793126
Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05152
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81994
t-cell acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.622639
GTEX-RTLS-2626-SM-46MUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_2_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3149740__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125403_3_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.67
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46217
Perturb_14502_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.0544
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90776
PMC7396444__F4	PFOCR Pathway Figure Associations 2024	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
5155877-6549	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079968
NB-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19776
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29097
aberrant	GeneRIF Biological Term Annotations	1.0	null
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02903
HNF4A_KD_GDS4798_550_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cystadenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95895516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23933
Organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.543
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82001
PMC4437475-mmc2.pdf-15-GCM1_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53167
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57522
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22706
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.595
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46025
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T8EM-0326-SM-3DB7F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848303
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06197
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.872778
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21884
BIM-BCL-xl complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.531
GTEX-TSE9-2526-SM-4DXUS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
RAMOS (RA.1) cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Abdominal Pain	CTD Gene-Disease Associations	1.0	1.20978
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JA-63-WB39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.688211
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97561
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.681
DOHH2	CCLE Cell Line Gene Expression Profiles	1.0	2.21687
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00565
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063359
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
HEL-92.1.7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03954
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08333
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.781478
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07648
GSE186654_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Crystalline style	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.49328
Lung squamous cell carcinoma_LUSC_TCGA-85-7843-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3761
CA46	CCLE Cell Line Gene Expression Profiles	1.0	3.03777
anabasine-2512	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71421
BRD-K21927299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27907
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349515
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61909412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71519
BRD-K21743103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00736
ZB-29-GC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.446268
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	3.76173
Perturb_4144_KO_Bcl11a/Bcl11b_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9723
stomach_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Mental Disorders	CTD Gene-Disease Associations	1.0	1.10699
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51873
direct	GeneRIF Biological Term Annotations	1.0	null
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MONOMAC6	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30864
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22348
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10876
regulation of mitochondrion organization	GO Biological Process Annotations 2015	1.0	null
Perturb_15007_KO_Hdac2_SRP097585	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.35823
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831363
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALOXONAZINE-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42435
BRD-K45498945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57188
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
members	GeneRIF Biological Term Annotations	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.22993
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retinitis pigmentosa 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
BRD-K33998683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39553
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06188
skmel30	HPA Cell Line Gene Expression Profiles	1.0	1.26
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042108
nterminal	GeneRIF Biological Term Annotations	1.0	null
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922803
BRD-K93023309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40624
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14574
BRD-K64567246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17751
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32544
Follicular dendritic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1678
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.667
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66924
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.403204
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCARA5_Down Expression_GSE32323_611_human_Colorectal Cancer Cell lines	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296615
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324444
BRD-K36544054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50139
MOLT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.92211
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02513
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Osteoclastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17163
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
BRD-K73899643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94051
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K08817808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75505
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73706189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37386
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ID-69-QF93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222071
PRKAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06151
YF-77-FV50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418547
contributes	GeneRIF Biological Term Annotations	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056767
folic acid-7201	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K51012353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0175
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.508242
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
suppresssed	GeneRIF Biological Term Annotations	1.0	null
PMC4091735__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
16822902-Table2	GeneSigDB Published Gene Signatures	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58382
astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416896
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59005
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.110905
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.04235
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Exanthema	CTD Gene-Disease Associations	1.0	1.18948
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_EZH2-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01117
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61041
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20846358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07886
FOXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08923
GTEX-OXRN-0226-SM-2I5EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947486
BRD-K30510226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37669
BRD-K94441949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07392
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
fp96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19377508-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1236
mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.357467
EZH2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.50713
NCIH660	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.65732
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059147
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A62469171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34677
several	GeneRIF Biological Term Annotations	1.0	null
SYK_druginhibition_281_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.33273
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06141
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90092568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87311
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal apoptosis	MPO Gene-Phenotype Associations	1.0	null
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0015
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6931
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08426
BRD-K94728263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11014
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897733
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW403	DepMap CRISPR Gene Dependency	1.0	2.2506
hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.340173
IPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16998
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
Polymorphonuclear neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
promoter	GeneRIF Biological Term Annotations	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97399
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87742
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74074
GSE155031_6_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.1461
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
PMC11479675-NIHMS2019542-supplement-2.xlsx-D_HIF1A_genes-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78496
myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102522
cem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341495
epigenetic	GeneRIF Biological Term Annotations	1.0	null
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.376847
INS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
stress	GeneRIF Biological Term Annotations	1.0	null
ChIP_K27me3_17603471_mouseNPC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07596
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99242
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24946605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94922
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
Ire1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.519
BRD-A28153253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93385
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5700962__F11	PFOCR Pathway Figure Associations 2023	1.0	null
positive regulation of protein-containing complex assembly	GO Biological Process Annotations 2025	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043269
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MCS-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.0159
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.54402
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1436
Hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
step	GeneRIF Biological Term Annotations	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21765
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYP20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02216
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
BRD-K58025976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08645
oncoprotein	GeneRIF Biological Term Annotations	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.49
T-lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02951
blockade	GeneRIF Biological Term Annotations	1.0	null
PMC8406487__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.51835
DE-81-OY65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222442
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.84937
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.78817
mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.582594
regulation of release of cytochrome c from mitochondria	GO Biological Process Annotations 2023	1.0	null
PMC12077596-NIHMS2076735-supplement-2.xlsx-CR_flag_RNA_SFPQ_TFE3-WT_dn-gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
mucilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.871483
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
appendix	HPA Tissue Protein Expression Profiles	-1.0	-1.00332
Dementia	HuGE Navigator Gene-Phenotype Associations	1.0	null
abnormal somatic nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-PWOO-1526-SM-48TCK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93683
Interdigit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15353
Perturb_4703_KD_Cpsf6_SRP265820	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
B3GNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7156
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39137
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_H3K27me3-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BB-87-SF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.440465
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14942
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60109
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
Apoptosis Modulation and Signaling(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
Brain cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21249
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76500652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18039
BRD-K53900606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53146
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
19838208-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.41884
PMC7325303__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_13865_KO_LIN28B_SRP284310	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.931
mRNA_ID1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4294
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.2041
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04361
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
S-117	GDSC Cell Line Gene Expression Profiles	1.0	1.92578
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0432
azaperone-5877	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25877
BRD-K20271299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.0015
diamond-blackfan anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.40008
PMC4727530__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pre-B acute lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
nervous	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49349
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
harakiri	GeneRIF Biological Term Annotations	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
pro-B-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.475
Polyuria	CTD Gene-Disease Associations	1.0	1.18751
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.13392
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29616
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
Multiple myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2726
diva	GeneRIF Biological Term Annotations	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K83143868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12794
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.1534
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10877
GSE155031_6_v_4_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Lung adenocarcinoma_LUAD_TCGA-97-8177-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-1026-SM-4BOPY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.642
Chl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3694
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92061
BGC-823 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
CDK8_knockdown_163_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.85601
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31182
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
severe	GeneRIF Biological Term Annotations	1.0	null
PMC3238295__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10566
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-1426-SM-48TD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K27973265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2759
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76434
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97241
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41912
BRD-K85633971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30065
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2437
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44215
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3012
Perturb_10442_KO_Zfhx3_SRP187824	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.322
BRD-K69987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03577
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073298
Hearing Loss, Sensorineural	CTD Gene-Disease Associations	1.0	1.26978
BRD-K65887908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11275
BRD-K33128056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36679
U2904	DepMap CRISPR Gene Dependency	1.0	2.08274
studied	GeneRIF Biological Term Annotations	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42735
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-GH-A9DA-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54944
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08992
PMC5728441__F1	PFOCR Pathway Figure Associations 2024	1.0	null
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18165
BNC1	Pathway Commons Protein-Protein Interactions	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.48299
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14825
Myelodysplastic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00676
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77979
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8983
PMC7849364-supp_gad.342378.120_Supplemental_Table_S4_.xlsx-Hoja1-Table_S4-_SIX2-associated_genes_identified_by_CUT_RUN_overlapping_with_differential_expression_by_SIX2_knockdown_SIX2	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.04126
GSE178340_1_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEL-HO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2605_OE_SEPTIN9_SRP159553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.07636
PMC10066286-42003_2023_4732_MOESM7_ESM.xlsx-Supplementary_Data_4-Supplementary_Data_4_Gene_effect_scores_in_TP53-altered_and_TP53-wild-type_AML_cell_lines_from_the_DepMap_datasets_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Diseases	CTD Gene-Disease Associations	1.0	1.04684
UM-UC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
UACC257	CCLE Cell Line Gene CNV Profiles	1.0	1.8599
DA-81-VY50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345908
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bid	GeneRIF Biological Term Annotations	1.0	null
PDIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28783
16542501-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
BRD-A55574211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00202
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29753
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.18603
ChIP_NACC1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Usher syndrome type 2D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K87595216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46645
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.045
ES5	DepMap CRISPR Gene Dependency	1.0	2.24923
nordihydroguaiaretic acid-6942	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78368
CREB1	ENCODE Transcription Factor Targets	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
A-Vietnam-1203-2004(H5N1)_18Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41156
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K65228230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97247
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.56008
mRNA_ZFAND3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K54260552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12057
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0432
ATM_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K51697562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73058
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30955
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13876_OE_ABCC1_SRP301382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923075
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88707941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14821
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3761
n18	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
abnormal paravertebral ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
LU-99A	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
I-kappaB/NF-kappaB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.544
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SC-25-HE80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.499022
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17188
sh-sy5y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446422
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09585
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75095
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.448742
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66525
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11935
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.567
BRD-K23553911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13735
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12218
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Activin responsive factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.296
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40251180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58817
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47574
Pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.78
bmf	GeneRIF Biological Term Annotations	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870019
PMC6488738-mmc6.xlsx-LHX8-Target_Gene_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UC-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dipyridamole-1517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44832
JARID2-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.469
Phosphatidylinositol 3-kinase complex, class III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
PMC4523019__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Methicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6961
PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887687
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24444
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A74Q-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43548
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC6070710__F11	PFOCR Pathway Figure Associations 2023	1.0	null
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041958
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-1626-SM-48FF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845557
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1867
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.79047
BRD-K06772291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00018
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80159
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pyridoxine-7171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
malignant pleural mesothelioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.210925
Perturb_3938_KD_GMDSAS1_SRP378936	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054949
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.368919
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09184
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213262
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FF-96-HL81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.385225
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
SKMEL5	BioGPS Cell Line Gene Expression Profiles	1.0	0.959989
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K88739137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19434
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.379
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12138
induced	GeneRIF Biological Term Annotations	1.0	null
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.125571
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.67002
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77320034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61399
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14455
PMC6606335__F5	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K69274755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28008
loss	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109421
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894801
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68157
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.58726
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29044
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03473
PPARG	ChEA Transcription Factor Targets	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	-1.0	-1.00332
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49408
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04645
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.41062
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.56947
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7786
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04663
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BE-57-VZ17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.568269
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065479
contribute	GeneRIF Biological Term Annotations	1.0	null
thapsigargin-7100	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
other	GeneRIF Biological Term Annotations	1.0	null
targeting	GeneRIF Biological Term Annotations	1.0	null
BRD-K15282657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14057
apoptotic process	GO Biological Process Annotations 2015	1.0	null
PMC5856858__F1	PFOCR Pathway Figure Associations 2024	1.0	null
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071313
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02610196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95112
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.22605
SNU398	CCLE Cell Line Gene Expression Profiles	1.0	1.55612
gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.279307
positive regulation of organelle organization	GO Biological Process Annotations 2025	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1168_KD_ETV6_ERP128093	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SW48	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00838
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52313
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6003
GSE193258,GSE193259_2_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08110534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30025
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	2.07674
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899868
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.12905
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17209411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27128
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plant mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32753
T-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
BRD-K55965167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4207
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0065
16103064-Table1	GeneSigDB Published Gene Signatures	1.0	null
CXCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86352
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877028
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26214026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66291
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08457
Lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.705
AD-54-FG24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247432
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53127464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14159
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RS411	Achilles Cell Line Gene Essentiality Profiles	1.0	1.47962
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10336
PMC7590567__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59549
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
EJM	CCLE Cell Line Gene CNV Profiles	1.0	2.31042
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	3.25029
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4474
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.375368
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
PMC4836210__F7	PFOCR Pathway Figure Associations 2023	1.0	null
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.685
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873849
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50355
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80865
Large cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
pre-T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
Bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.339
BRD-K03765511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7302
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844548
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968893
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044588
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PARK7_KD_GDS3750_2_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320956
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85664064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9297
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36107
Leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.077
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.879867
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K51160592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45213
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BB-27-MC77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271377
PMC9377669-tx1c00392_si_002.xlsx-Entinostat-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14347
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
B-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916394
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16191
hsa-miR-876-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829184
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80726
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21919
GSE126463_5_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
17760805-SuppTableS2a	GeneSigDB Published Gene Signatures	1.0	null
BRD-K63587749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05464
Perturb_4164_KO_Erbb4_SRP373176	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.72676
INS-1E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69366
Vasculitis, Leukocytoclastic, Cutaneous	CTD Gene-Disease Associations	1.0	1.06008
abnormal dorsal root ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
FAR/SIN/STRIPAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85803
MYOD1	ENCODE Transcription Factor Targets	1.0	null
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
Human - Tonsil - L1 - preB/T	HuBMAP Azimuth Cell Type Annotations	1.0	null
CRIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5975
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69412
BRD-K03791970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63735
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Headache	CTD Gene-Disease Associations	1.0	1.19737
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62581
BRD-K80736363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28258
BRD-K76431854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04285
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42071
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
15257931-SuppTableA	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
Perturb_14245_KO_IKZF3_SRP139731	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27322
BRD-K30284601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33254
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10905
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-5096	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068568
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.110983
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08856
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	1.52316
Vasculitis	CTD Gene-Disease Associations	1.0	1.09892
positive regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
PET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
BRD-K98088240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04311
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10917_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.9672
Attachment organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
NFYA	ENCODE Transcription Factor Targets	1.0	null
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50196
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44518
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K39773004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4334
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94665
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087113
BRD-K37262603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21366
contains	GeneRIF Biological Term Annotations	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4274
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
BRD-K17753780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34103
BRD-K03353688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25527
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52045
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ATF5_ATF5	Rummagene Transcription Factor Associations 2026	1.0	null
gamma-tubulin large complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19292
BRD-K58324650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06249
BRD-K25484053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86689
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2174
BRD-K47415214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01794
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26607
pre-B-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.465
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47512
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
LM6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975304
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Germinal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.48119
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.859
LUBAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07888
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
PMC9377669-tx1c00392_si_002.xlsx-Buspirone-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66905
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17535
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937805
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21782
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.7852
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Promonocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
PMC4791243-oncotarget-06-43452-s006.xlsx-Supplementary_table_S5-Supplementary_table_S5_Differentially_expressed_genes_in_TP53_mutant_versus_TP53_wild_type_cell_lines_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.41399
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	2.06223
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03312699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32852
Plume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0026
20035825-TableS7a	GeneSigDB Published Gene Signatures	1.0	null
AC-75-CE67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.391164
Endoplasmic reticulum chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Ensemble_gene_ID_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15231
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.43098
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068918
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.44
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072612
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pleopod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
BRD-K54834493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19899
Daudi	GDSC Cell Line Gene Expression Profiles	1.0	1.81777
positive regulation of release of cytochrome c from mitochondria	GO Biological Process Annotations 2015	1.0	null
EWSR1_KD_GDS4962_467_human_not specified	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHP-134	GDSC Cell Line Gene Expression Profiles	1.0	1.74524
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42023
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.96806
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66589
Pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
BRD-K95863777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10448
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35825
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05885
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27943
biological regulation	GO Biological Process Annotations 2015	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Folic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6890986__F3	PFOCR Pathway Figure Associations 2023	1.0	null
MCM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05066
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74251295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62803
cell part	GO Cellular Component Annotations 2015	1.0	null
BRD-K04546974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16364
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08587
BRD-K74676765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07764
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32886
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30472
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45407
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0666
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	2.0547
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03879
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
pi-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
BRD-K10784927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00003
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36662
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32423
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
BRD-K88997070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02999
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
sw837	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918027
BRD-K84115096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60774
colorectal	GeneRIF Biological Term Annotations	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2841
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.90107
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20493
BRD-K97472167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01818
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76202128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54728
PMC6172027-elife-38795-fig2-data2.xlsx-XBP1_RNASeq_only-Gene_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02299
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33522
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39608
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32444
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974591
PMC10095465__F1	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2189
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08862
BRD-K66754362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01742
abnormal sympathetic ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
PHA-00767505E-6550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.960378
BRD-K24156533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25485
Reticulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24227
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01699883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33407
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00676
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224364
AX-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
binding	GO Molecular Function Annotations 2015	1.0	null
Marginal zone lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246712
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
BAD-BCL-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.546
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87089
abnormal cranial nerve morphology	MPO Gene-Phenotype Associations	1.0	null
proadifen-3446	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE155031_6_v_7_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29673
BRD-K50177754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27112
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08629
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3747
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02512
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99726
Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08232
BCL2L1	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.798
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01225
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_13878_OE_ABCC1_SRP301382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.77869
dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.277227
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cyproheptadine-1521	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34664417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10387
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2431
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23903
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18409
BRD-K64922699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29748
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.77878
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20732
TAF1	ENCODE Transcription Factor Targets	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31992830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63319
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41385
PMC4091735__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91620436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20584
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17852
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.569
Amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8531299__F1	PFOCR Pathway Figure Associations 2024	1.0	null
MV4-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08649
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00142
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052665
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1532
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.897751
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12368
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3I6-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cornu ammonis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
Lacquer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.75163
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058901
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341863
ASTRA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
Brain structure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.51549
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9466
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trimethylamine-N-oxide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
OAW42	DepMap CRISPR Gene Dependency	1.0	2.13744
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
RNF2	ENCODE Transcription Factor Targets	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055684
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20756
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25057
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16245
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.23743
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.847
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03044
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K71870778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32691
BRD-K10031593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67686
Retinal cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-TM_KO_vs_WT-Supplementary_Table_S2-2_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_TM_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-AS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
BRD-K06208179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33652
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70148902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10975
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82212
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.571329
CORL23	CCLE Cell Line Gene Expression Profiles	1.0	1.38715
fluorometholone-2509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.735
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
pleural cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.208579
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60952
17724462-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	256.672
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02972
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Schopf-Schulz-Passarge syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
PMC4439078__F5	PFOCR Pathway Figure Associations 2023	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_SUZ12-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COLO-205	GDSC Cell Line Gene Expression Profiles	-1.0	-1.87881
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248858_6_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MSTO-211H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26402831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52921
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5439-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64259
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
inducers	GeneRIF Biological Term Annotations	1.0	null
GSE166184,GSE166185_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78088874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66737
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.04647
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0343
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067071
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
0179445-0000-4758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.50963
heterozygosity	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6606335__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39572
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062227
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.94235
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
daudi	HPA Cell Line Gene Expression Profiles	1.0	0.961465
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40056
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99183
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.64
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31366
pf382	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
methazolamide-2733	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
nucleotide-excision repair factor 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9535
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Elaioplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.051
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44893
MEWO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
BRD-K84990603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09581
Small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
CTDSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44813
Acute myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.624
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
structural	GeneRIF Biological Term Annotations	1.0	null
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
appears	GeneRIF Biological Term Annotations	1.0	null
abnormal cell death	MPO Gene-Phenotype Associations	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
NCI-H460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37137
Chronic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S10_DGEA_IKZF1-Supplemental_Table_10_Differentially_expressed_genes_between_IKZF1_and_all_other_subcluster_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chronic myelomonocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
DHL-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
Mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.695
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.93152
GSE133683_1_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318621
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859411
hsa-miR-297	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926083
HEK 293T	BioGPS Cell Line Gene Expression Profiles	1.0	1.34341
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.627388
ATF	MotifMap Predicted Transcription Factor Targets	1.0	null
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32493
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_15797_OE_EMP2_SRP265560	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.96031
microsporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196064
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
lymphocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085004
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5926
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7519_OE_CCDC152_SRP217791	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.03054
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045478
RBBP5	ENCODE Transcription Factor Targets	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62063
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
trichuriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.322273
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04283
ZNF143	ENCODE Transcription Factor Targets	1.0	null
BRD-K01237500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11907
MD-17-VD78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329918
OELE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49075
BIM-BCL-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.641
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.339
Cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Anemia, Hemolytic	CTD Gene-Disease Associations	1.0	1.10069
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.682332
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sk-n-sh cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19202
UACC257	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC4727530__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.15146
Perturb_9446_KO_STK25_SRP356933	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.8811
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86892
Apoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.628
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56067
JVM3	CCLE Cell Line Gene CNV Profiles	1.0	1.43267
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC7139457__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone Diseases	CTD Gene-Disease Associations	1.0	1.15089
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7503
MDAMB436	CCLE Cell Line Gene Expression Profiles	1.0	1.97052
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38242
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66715657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1391
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09862
PMC3534415-1755-8794-5-26-S1.pdf-4-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
dohh2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
Heart Diseases	CTD Gene-Disease Associations	1.0	1.46781
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854309
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.825021
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.519
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21206585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19524
Large B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.163866
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33647
BRD-K47707657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19501
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38138
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.03
positive regulation of apoptotic signaling pathway	GO Biological Process Annotations 2015	1.0	null
BRD-K18930370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57775
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Pharate pupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.693
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32849
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX21_SOX21	Rummagene Transcription Factor Associations 2026	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07099
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3149740__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
BRD-K31233830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45004
PMC6855629-pone.0225186.s003.xlsx-Sheet1-DEGs_repressed_by_MEIS1_in_human_cell_lines_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50857
mantle cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34926
BRD-K98089885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35591
KG-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
Cognition Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
BAD	Pathway Commons Protein-Protein Interactions	1.0	null
Acute lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.671
SYK_druginhibition_285_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7626
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
XB-53-OZ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280758
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3414384__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844642
embryos	GeneRIF Biological Term Annotations	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055057
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K35035851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34697
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.606257
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970847
BCL2A1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68463
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
sup-t1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483986
Perturb_8483_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.01417
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122067_3_v_0_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.52667
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.3005
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079158
PMC2924379__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_16821_KD_Miat_SRP379156	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14455
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82212
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14772
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34257
SK-N-MC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.11615
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34005205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19045
atf4	GeneRIF Biological Term Annotations	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08649
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transection	GeneRIF Biological Term Annotations	1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
Alzheimer's disease (age of onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58539
Perturb_15822_KO_PINK1_SRP343083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.24976
DBTRG-05MG	GDSC Cell Line Gene Expression Profiles	-1.0	-2.9207
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4599
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.821
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37772
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.277
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Perturb_8484_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.4794
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.524108
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33503
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PDPN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526643
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.827267
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26828
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.941567
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76211
Perturb_17229_KO_Tsc1_SRP096336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.06479
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K18888894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53765
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42814713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31613
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158605
OC-10-FB51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220275
Perturb_17952_KO_Shank2_SRP314506	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.48951
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
BRD-K92879007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20237
PMC7411521__F4	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K37975989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20069
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vas efferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.498
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased apoptosis	MPO Gene-Phenotype Associations	1.0	null
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.65541
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25778
binds	GeneRIF Biological Term Annotations	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143316_3_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OE-75-WF43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232028
BRD-K28057105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59278
cterminal	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31452
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_ZFP281_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Perturb_13929_KD_NBAT1_SRP221510	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7064337-elife-51373-supp1.xlsx-SUZ12_targets_shPHF19-List_of_567_genes_marked_by_SUZ12_ChIPseq_iafter_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.312827
BRD-K96101240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16518
BRD-K74324157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73118
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56891
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02563170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03217
HCC1187	Achilles Cell Line Gene Essentiality Profiles	1.0	2.06022
20081105-ST-1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
NCI H226	BioGPS Cell Line Gene Expression Profiles	1.0	0.894458
BRD-K81949875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45132
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00557942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92513
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223561
CCRF-CEM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BA-92-CZ75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258916
Hearing Loss	CTD Gene-Disease Associations	1.0	1.06661
gl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04593
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6906-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47673408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08554
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51281
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918248
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
CA46	GDSC Cell Line Gene Expression Profiles	1.0	2.51026
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Supplementary_Table_2F_Contrast_ATF4-def_IGG_8h_vs_HCT116_IGG_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Nausea	CTD Gene-Disease Associations	1.0	1.55896
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275794
BRD-K09720842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07467
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50138
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56735
ldr7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.683
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
SK-N-DZ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61994
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.56436
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.548122
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36166
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950009
Perturb_8642_KD_Tet3_SRP056501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.8539
GSE164874_5_v_2_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-39-BD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314836
NCI-H929 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.39254
hsa-miR-1207-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CBX2	ENCODE Transcription Factor Targets	1.0	null
BRD-K43192646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27655
review	GeneRIF Biological Term Annotations	1.0	null
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24528
GSE111247_11_v_9_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206400_3_v_0_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Extrahaustorial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.46232
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055232
PMC3844829__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Cerebellar granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.603
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127401
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8589
Perturb_14089_KO_SMARCA2_SRP295674	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
diverse	GeneRIF Biological Term Annotations	1.0	null
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.61315
SW48	GDSC Cell Line Gene Expression Profiles	-1.0	-1.96607
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.926374
Myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.825
BRD-K00591281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12712
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866079
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	2.00077
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IMR32	CCLE Cell Line Gene Expression Profiles	1.0	1.74324
MCL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE70499_4_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.31946
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35915
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972729
ANAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45958
IKBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10428
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932707
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Astrocytoma	DisGeNET Gene-Disease Associations	1.0	null
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
eoc	GeneRIF Biological Term Annotations	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992607
SMAD3	ChEA Transcription Factor Targets	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064306
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
EB-3	GDSC Cell Line Gene Expression Profiles	1.0	1.89711
regulation of organelle organization	GO Biological Process Annotations 2015	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.725847
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	0.825254
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01169
15856041-Figure1	GeneSigDB Published Gene Signatures	1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919901
AA-94-TU18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.530345
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13801
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956815
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.77695
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03825
at95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
Small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18277
KMS28BM	CCLE Cell Line Gene Expression Profiles	1.0	1.35249
Tal-1beta:ITF-2	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04428
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14942
Kasumi-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
hsf1_19179333_rko_colon_carcinoma_lof_human_gpl6244_gse12762	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.006492
PF-84-RH50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.484519
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
GTEX-W5X1-1426-SM-3GIKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-PWOO-1026-SM-48TCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Protein serine/threonine phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.101
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066236
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01658
16715129-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.503441
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93035
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05615
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Molaris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110993
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
Neurologic Manifestations	CTD Gene-Disease Associations	1.0	1.05793
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.5926
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U8-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
JJN3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12838
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846404
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SYK_knockdown_279_GDS3609	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.60384
BRD-K11008696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29679
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventricular zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
Medulloblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
ELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10673
dr9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06425
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cotinine-1511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.33528
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.12787
PMC8431385__F2	PFOCR Pathway Figure Associations 2024	1.0	null
lacking	GeneRIF Biological Term Annotations	1.0	null
Perturb_11151_OE_Aeg1/Myc_SRP048459	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.39694
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.37448
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977359
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03692
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F1	ENCODE Transcription Factor Targets	1.0	null
BRD-K96106084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37813
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.02365
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K85977749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23773
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266757
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.756
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.05959
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70317
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54294
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234984
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079997
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065106
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K39176069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86615
Marginal zone lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6516-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTDK-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18074484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03303
BRD-K81995936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8902
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.739
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19132
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02264
Subiculum volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7
B-cell acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14024
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
PMC9377669-tx1c00392_si_002.xlsx-Magnesium_Cl-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870524
Dentate gyrus molecular layer volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.4699
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-937 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
PTEN_01_302	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58869
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968736
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7308_KD_IER3AS1_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.03266
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60783
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300618
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.39165
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.883239
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4060771-170289.f1.pdf-622-NEUROD1_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11409
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95988
Perturb_5237_KO_Abhd11_SRP237744	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.19197
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
KIF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39135
MYC-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195559_8_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09313
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phosphatidylinositol 3-kinase complex, class I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.818
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5036
BRD-K68683482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35003
critical	GeneRIF Biological Term Annotations	1.0	null
GSE201520_8_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Leflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F3_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.147
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52689
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60049
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890952
non-Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.4
mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
PMC3012117-pone.0015793.s008.xls-Sheet1-Table_S3_The_list_of_TFE3_regulated_genes_with_MiTF_TFE_binding_sequence_in_their_promoters_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal sensory ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64472
fluoxetine-5356	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918313
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
carbinoxamine-3466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.2046
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74646
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6861914__F7	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ESRRB	ChEA Transcription Factor Targets	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02755
B-cell lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT1376	CCLE Cell Line Gene Expression Profiles	1.0	1.46479
t-lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.130237
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
Teratocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34331
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43414
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46157
Hypertrophy	CTD Gene-Disease Associations	1.0	1.48376
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00387
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09377
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.03009
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37194
Lung adenocarcinoma_LUAD_TCGA-50-5939-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6041399__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961456
SMAD4	ChEA Transcription Factor Targets	1.0	null
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
DE-73-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.383607
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02952
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82571240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25186
GTEX-S32W-0326-SM-2XCBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843079
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2426-SM-4E3HX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02539
pancreatic	GeneRIF Biological Term Annotations	1.0	null
NCIH2171	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.06824
TCF3	ChEA Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21802
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.610548
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855171
BRD-K83108629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19517
inactivation	GeneRIF Biological Term Annotations	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.6824
PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
foxa1_21151129_mcfdash7_lof_human_gpl10558_gse25315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.270539
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064855
SUP-T1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
dbsfrhl2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092034
PMC8166497__F5	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25983
bone marrow cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077985
BJAB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91662
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01612
oxybutynin-6770	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906952
Myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.452
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25877
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06052
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48687
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842088
Retinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10148
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170544
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3066
BRD-K60932633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29324
Perturb_8628_KO_Pyk2_SRP329328	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.9962
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938455
chronic lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.184675
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.906037
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
19139136-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06335
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
PMC6488738-mmc6.xlsx-ISL1-Target_Gene_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
fluocinonide-4314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3K7-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_25_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
albendazole-7164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840871
Plastid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38752
ZNF808	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39268
external encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.202346
MEG-01	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50794
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
SIN3A	ENCODE Transcription Factor Targets	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ALL-SIL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
amidopyrine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7673
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92062
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
HSPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00631
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
griseofulvin-7363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97226
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	2.32582
ZFP281-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87781745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23518
DA-81-VY50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270641
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.107
PMC4470057-12943_2015_398_MOESM7_ESM.xls-probes_KD_inh_in_common-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of protein oligomerization	GO Biological Process Annotations 2015	1.0	null
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00519
Mature B-cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053795
Hyperplasia	CTD Gene-Disease Associations	1.0	1.14132
epithelial ovarian cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.342602
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.31467
CRCGN014_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19245
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
positive regulation of programmed cell death	GO Biological Process Annotations 2025	1.0	null
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10396
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47274
PMC9377669-tx1c00392_si_002.xlsx-Retinol-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
model	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824786
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8045_KD_ST18_SRP062868	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.68953
single-organism process	GO Biological Process Annotations 2015	1.0	null
BRD-K75036062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74425
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.23042
BRD-K16698502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57154
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17935
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936442
Lung squamous cell carcinoma_LUSC_TCGA-68-7756-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312595
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057457
BRD-K52613522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34659
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05923
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST12-eQTM_Gene_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34169251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00191
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07684
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52127
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14446
PMC9377669-tx1c00392_si_002.xlsx-5_5-Diphenylhydantoin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47170544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17506
BRD-K92884779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53
regulation of release of cytochrome c from mitochondria	GO Biological Process Annotations 2025	1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
induction	GeneRIF Biological Term Annotations	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.682287
A-CA-04-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.18665
BRD-K93697231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0066
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04603
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19461
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.600202
19185848-Table1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-XUZC-0326-SM-4BOO8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K96733881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08391
PMC12209767-bcd-25-0099_supplementary_table_s2_suppst2.xlsx-C_DEGs_RNA-seq-Supplementary_table_S2C_List_of_differentially_expressed_genes_in_IGHUND_vs_IGH_GCB_MB2_DE_DLBCL_HGBCL-DH-BCL2_-BCL6_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03184
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36107
ZNF682	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81137
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.958883
astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.415398
PMC12855817-41698_2025_1249_MOESM1_ESM.pdf-2-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26569
ATF1	MotifMap Predicted Transcription Factor Targets	1.0	null
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29396
WA-15-KX40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246651
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05842
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11935
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243294
Perturb_1359_KD_MTOR_SRP331117	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112763,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.786468
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35718
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52542
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24514314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87275
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58382
B cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of release of cytochrome c from mitochondria	GO Biological Process Annotations 2025	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5899
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_neg_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.984362
positive regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38946705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2446
BRD-K87080069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36095
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
IgM B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
HNF4A_KD_GSE29084_694_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12392
Wolcott-Rallison syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
nomifensine-5863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53173
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary	GeneRIF Biological Term Annotations	1.0	null
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82218
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58808
SF767	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00376
Carnitine	CTD Gene-Chemical Interactions	1.0	null
Infertility, Female	CTD Gene-Disease Associations	1.0	1.02373
Perturb_5284_KO_BACH1_SRP143680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00565
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Perturb_3673_KO_SLC25A4_SRP372860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
T-cell acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.315
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61886116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78287
oocytes	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rhabdomyolysis	CTD Gene-Disease Associations	1.0	1.02933
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
PMC9377669-tx1c00392_si_002.xlsx-9-cis_retinoic_acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
DAUDI	CCLE Cell Line Gene Expression Profiles	1.0	1.98803
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.95316
Brain Lower Grade Glioma_LGG_TCGA-DU-6394-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RC-21-IF98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248408
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.951878
positive regulation of protein homooligomerization	GO Biological Process Annotations 2015	1.0	null
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5208
BRD-K10696228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83632
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal neuron apoptosis	MPO Gene-Phenotype Associations	1.0	null
MHH-PREB-1	GDSC Cell Line Gene Expression Profiles	1.0	1.64439
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.412
GSE116580_0_v_1_smug1_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal somatic sensory system morphology	MPO Gene-Phenotype Associations	1.0	null
DJM-1	GDSC Cell Line Gene Expression Profiles	1.0	1.54835
PMC9377669-tx1c00392_si_002.xlsx-Chlorophenamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8634_KO_Htr6_SRP223109	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.325
activators	GeneRIF Biological Term Annotations	1.0	null
Perturb_2224_KO_Capn1_SRP225119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.78217
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21867
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ML-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurodegenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
PMC10905894__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88699
BRD-K37544873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47371
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12546_KO_Shank2_SRP309197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.87177
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29804
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936109
BRD-K31204557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46956
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57368
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857946
BRD-K25256659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53647
positive regulation of organelle organization	GO Biological Process Annotations 2015	1.0	null
semustine-7545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087339
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UE-02-UW61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210598
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17672
BRD-K03093950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36125
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
ccrf-cem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265381
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Serous cystadenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A822-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mantle cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43273
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LK-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
knockdown	GeneRIF Biological Term Annotations	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ML-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
GSE85874_4_v_5_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8000576__F1	PFOCR Pathway Figure Associations 2023	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Lithium_Chloride-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12089436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31306
intracellular part	GO Cellular Component Annotations 2015	1.0	null
sulfadimethoxine-7400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6527025__F2	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39273
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.232
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.82635
bacterial meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.197742
sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133218
BRD-K40490682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95718
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
L-5178-Y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
11-deoxy-16,16-dimethylprostaglandin E2-7533	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75963
drug-induced hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Gene_name_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11525028-mmc6.xlsx-Sheet1-ATF4_target_genes_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
JVM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.01335
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47394
report	GeneRIF Biological Term Annotations	1.0	null
BRD-K62229896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36175
BRD-K89000000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32756
Calu-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89595887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13678
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
BRD-K40649636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4355
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.16692
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80346
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0471
RNF2	ChEA Transcription Factor Targets	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09248
leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.875706
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55546
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.36133
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6484-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08703292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00594
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.42364
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.54306
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3R5-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
death	GO Biological Process Annotations 2015	1.0	null
Apoptotic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.783
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12177
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of apoptotic signaling pathway	GO Biological Process Annotations 2015	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-1126-SM-4DXUG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
Eye-corneal epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	10.8708
Chronic myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
EC-01-PH79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329247
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36865
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
Enamel knot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.86606
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE450	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00397
Outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.648
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.76655
PMC9377669-tx1c00392_si_002.xlsx-Vismodegib-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66708851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56875
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.841102
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55151
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06466
BRD-K94629607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06623
BRD-K37527826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03994
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16840_KO_Bcl11b_SRP340294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.986
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26248
BRD-K73994499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73828
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CX-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
Kidney Failure, Chronic	CTD Gene-Disease Associations	1.0	1.0353
Perturb_8515_KO_Satb2_SRP068801	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.72492
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917315
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19572
NACC1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YO-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB	MotifMap Predicted Transcription Factor Targets	1.0	null
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
DLD-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11457
DASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
Lung squamous cell carcinoma_LUSC_TCGA-56-A5DR-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
GSE169152_5_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
nulliscc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K56729241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19541
promotes	GeneRIF Biological Term Annotations	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.27782
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0246
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41926
Brain Lower Grade Glioma_LGG_TCGA-E1-5305-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096284
Demyelinating Diseases	CTD Gene-Disease Associations	1.0	1.01437
BRD-K41809155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2747
CRCGN012_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29183
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.76385
BRD-K51278788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79465
Thymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.486
Agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K92776249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18892
HCC-15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754552
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24676
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07711
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.34196
mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195601
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Aleurone grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of protein-containing complex assembly	GO Biological Process Annotations 2023	1.0	null
BRD-K29144638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5417
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7576
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
UACC62	BioGPS Cell Line Gene Expression Profiles	1.0	1.15297
lymphoma, non-hodgkin; lymphoma, non-hodgkin's	GAD Gene-Disease Associations	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal hypoglossal nerve morphology	MPO Gene-Phenotype Associations	1.0	null
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73831
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20789
rgcs	GeneRIF Biological Term Annotations	1.0	null
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207293
sequences	GeneRIF Biological Term Annotations	1.0	null
Perturb_418_KD_EHF_SRP049988	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88889
BMI1	ChEA Transcription Factor Targets	1.0	null
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41888
TP53	ChEA Transcription Factor Targets	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10672
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
b-cell chronic lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58225
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.116
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K98249237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3931
PMC2924379__F2	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K45537529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0287
Perturb_14983_KO_Hdac2_SRP097585	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.6969
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A2J0-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56015010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26402
abnormal sympathetic system morphology	MPO Gene-Phenotype Associations	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.3395
NCI-H2170 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846441
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1527
cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.229888
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.502
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.841
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.16953
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Bone marrow cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Methorexate-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0434
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926792
Gentamicins	CTD Gene-Chemical Interactions	1.0	null
Mitochondrial outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.746
hsa-miR-875-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21023
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0507
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of cellular component biogenesis	GO Biological Process Annotations 2023	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404418
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.44323
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05509844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66902
Perturb_4335_KD_PML_SRP221023	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K64722080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08411
BRD-K27911943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45724
diazoxide-7168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53706972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38678
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065152
Mycolate outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292079
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K35259368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00035
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05963
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8516
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47238978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58462
Total hippocampal volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.4699
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.443936
17009876-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00274
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78055
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.855428
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43728
BRD-K30661365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07732
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249565
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914188
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997995
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073465
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Organelle outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.742
PMC7590567__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_9_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_1310_KO_Cntnap4_SRP387040	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.15939
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.57229
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05953
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50385
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	186.16
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07279
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
U-698-M	GDSC Cell Line Gene Expression Profiles	1.0	1.82528
abnormal neuron physiology	MPO Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47228832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01376
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863004
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22492
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856568
lipotoxic	GeneRIF Biological Term Annotations	1.0	null
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34192
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09717
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33973
Memory Disorders	CTD Gene-Disease Associations	1.0	1.70886
Lung adenocarcinoma_LUAD_TCGA-64-5781-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tumor necrosis factor receptor superfamily complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.236
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2729
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05131
CREB1	ChEA Transcription Factor Targets	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331695
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43513
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9501
BRD-K50859531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75505
JARID2-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07884
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11758
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.815
venous insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.41465
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042715
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77291
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1326-SM-4IHJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47092
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Presubiculum volume (corrected for total hippocampal volume)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4699
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7409-01A-31R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.8608
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06451
Perturb_12901_KD_ZBP1_SRP298473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30069
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3839
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38381
PMC4523019__F2	PFOCR Pathway Figure Associations 2024	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BL-41	GDSC Cell Line Gene Expression Profiles	1.0	1.52617
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01442
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982314
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
PMC8998228__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA1_201_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC1716201__F1	PFOCR Pathway Figure Associations 2023	1.0	null
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225648
Spinal Cord Diseases	CTD Gene-Disease Associations	1.0	1.07163
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76211
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
non-hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060977
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5787-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.49789
T-lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2478
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Ascorbic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Supplementary_Table_2A_Contrast_ATF4-def_control_vs_HCT116_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2543
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83553001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9377
Cellulose microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.816745
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877753
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59099886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37424
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938038
BRD-K53046137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08146
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043179
CHOP-C/EBP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
BRD-K31273080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68346
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-WFJO-1126-SM-4LVLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38488
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.00332
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9886
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9925
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07648
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891959
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-SI-A71O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
upregulated	GeneRIF Biological Term Annotations	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.863
optic	GeneRIF Biological Term Annotations	1.0	null
KARPAS-422 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941524
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70613
EC-82-LV30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361239
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.41063
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07194
GSE126463_6_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08255
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45388
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Doxylamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Thalidomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pain	CTD Gene-Disease Associations	1.0	1.43919
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2671
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047206
BRD-K02747732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26905
Ripoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.229
usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.303781
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592043
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.494403
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.77414
Transfer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PB-63-WH18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.738099
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31921
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27389
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25619
Perturb_8355_KO_ZCCHC4_SRP345783	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.38028
Mitochondrial crista junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07215
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7076
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54423
Rheaume et al.Nat Commun.37_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
prostate_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
19334046-TableS3a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.41582
Retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
RING1B-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.95485
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.346409
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
system	GeneRIF Biological Term Annotations	1.0	null
mitochondria	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUW1-1526-SM-4BOOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83372
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SYK_druginhibition_284_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.3695
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K74817844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18091
TE14	CCLE Cell Line Gene Expression Profiles	1.0	1.53827
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.608241
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04223
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239913
Multiple Myeloma	CTD Gene-Disease Associations	1.0	1.03678
regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57525
BRD-K75440064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25713
BRD-K74811560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22818
BRD-K14181473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36212
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.831
BRD-K90977883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11428
BRD-K35058762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02918
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28034484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02507
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.49561
BRD-K04695993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96805
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.83612
GSE147366_3_v_5_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of cellular component organization	GO Biological Process Annotations 2025	1.0	null
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15816_KO_PINK1_SRP343083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.45348
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67931592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15762
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4271
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94876980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04581
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.5
cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043633
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mycosis fungoides	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170789
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Perturb_17564_KO_Runx3_SRP074412	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.99051
DPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.713
GATA3	ENCODE Transcription Factor Targets	1.0	null
PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23914
GTEX-XV7Q-2626-SM-4BRVA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889612
Perturb_12548_KO_Shank2_SRP309197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.41195
PMC9377669-tx1c00392_si_002.xlsx-Favipiravir-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07726
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of protein-containing complex assembly	GO Biological Process Annotations 2025	1.0	null
BRD-K37763427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16942
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
decreased neuron apoptosis	MPO Gene-Phenotype Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25513
H3K27me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12565
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4563120__F5	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K89832379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01815
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95964
b-lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241132
CDC42EP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26389
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29966
LCLC103H	CCLE Cell Line Gene Expression Profiles	1.0	1.69088
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.16892
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.35945
beta-galactosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.144
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62534
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
p32	GeneRIF Biological Term Annotations	1.0	null
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056486
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr12_116889846_G_T_b38	GTEx eQTL 2025	1.0	2.11821
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37203382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12371
GSE116810_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92765
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84384
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14825
BRD-K75164441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30255
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HATA volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.23979
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6985
BRD-K72807299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1245
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.536
BRD-K65910757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91469
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028084
Hippocampal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Perturb_5236_KO_Abhd11_SRP237744	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.79188
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HL-60 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.868
KATO-III cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1021
Perturb_14754_OE_SLC28A3AS1_SRP303692	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.2291
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0018
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044557
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
HEK-293FT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81110981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36152
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Apoptosis	WikiPathways Pathways 2024	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Chronic lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.839165
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
pyrantel-2097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233909
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900552
Organelle envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.072
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09082
reticulum	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.01933
C6 glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
Perturb_11551_OE_SIRT6_SRP394380	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.82427
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59997
Perturb_4143_KO_Bcl11a_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.67996
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
SPECC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73963
Organelle envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.602
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.06893
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57767
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36501
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06621
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.971993
PMC5657403__F1	PFOCR Pathway Figure Associations 2023	1.0	null
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
PMC12436161-41388_2025_3507_MOESM1_ESM.pdf-13-ENSG00000121068_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41315
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K18645499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62119
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXO3_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
JARID2	ChEA Transcription Factor Targets	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.344
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.35892
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.18126
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0126
PMC9377669-tx1c00392_si_002.xlsx-Ampicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
RNF2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18049
19074878-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542165
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01921
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10923
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
protein binding	GO Molecular Function Annotations 2015	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4748
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12365
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.787299
regulation of protein complex assembly	GO Biological Process Annotations 2015	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.02188
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.096655
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
bh3only	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
sulfachlorpyridazine-4326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
non-Hodgkin lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
BRD-K62758843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68746
positive regulation of signaling	GO Biological Process Annotations 2015	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
regulation of cellular component biogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74134
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63W-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7325303__F1	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
BRD-K49635910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16798
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A840-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6488738-mmc6.xlsx-PBX3-Target_Gene_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902894
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.627761
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77276
PMC7674767__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TOLEDO	CCLE Cell Line Gene Expression Profiles	1.0	1.57024
Mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.13979
RITA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08882
BRD-K72700187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0812
BRD-K06203932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17954
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP281-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.26452
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.1294
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10434_KO_PPFIA1_SRP127326	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.07931
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	3.95591
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19945
liberating	GeneRIF Biological Term Annotations	1.0	null
death	GeneRIF Biological Term Annotations	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01516
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02839
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343936
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K15940471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38953
SK-N-SH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
Perturb_10867_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.72045
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28613
Anisometropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.992355
decreased	GeneRIF Biological Term Annotations	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17871
SUZ12	ChEA Transcription Factor Targets	1.0	null
SW1088	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65619
non-hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.659897
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K17416171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07946
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
Chloroplast photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K29264158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12409
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79568363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0061
bad-bcl-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.00448
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.599
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.811001
Amyloplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
Perturb_15034_KD_WDR5_SRP024294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.01757
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26251149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00299
sulfaquinoxaline-6788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65949
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.445
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
DNA gyrase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Ranitidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
Acute promyelocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920198
PMC6861914__F7	PFOCR Pathway Figure Associations 2023	1.0	null
ChIP_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
19074878-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
status	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01488
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35068
Perturb_4236_KD_Cnot7_SRP091584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.4277
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Leaf base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.24492
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22204
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34868
upregulation	GeneRIF Biological Term Annotations	1.0	null
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-6.34711
inhibiting	GeneRIF Biological Term Annotations	1.0	null
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86977
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.09254
Cardiomyopathies	CTD Gene-Disease Associations	1.0	1.4332
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
Uremia	CTD Gene-Disease Associations	1.0	1.06808
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EC-01-PH79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.503965
Mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
lm11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
BAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.379
bak	GeneRIF Biological Term Annotations	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.96833
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00122
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98262
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09695
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATN-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67321
PMC4605373__F4	PFOCR Pathway Figure Associations 2023	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Stipule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
epirizole-1681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62873
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827907
Human - Bone Marrow - L2 - Transitional B	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-1160_PS-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphatic edema_Skin tissue_GSE4333	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.32413
preimplantation	GeneRIF Biological Term Annotations	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypermethylation	GeneRIF Biological Term Annotations	1.0	null
DE-20-VX20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.429624
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.56484
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0923
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44483
abnormal dorsal root ganglion morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1118_KD_SENP6_SRP328207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.80621
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35521
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.05439
BRD-K11027431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51353
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28206
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891959
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21426
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MTF2	ChEA Transcription Factor Targets	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09718
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37761
BRD-K58680513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07555
GSE158834_11_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
b82	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043138
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34985075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21919
BF-94-GX05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231563
Cystadenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
apoptotic	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20470077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03857
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26443
A-375 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
SYK_druginhibition_286_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.62201
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.72294
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Paroxetine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
cell death	GO Biological Process Annotations 2015	1.0	null
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Perturb_10868_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.70055
valinomycin-5957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6070710__F11	PFOCR Pathway Figure Associations 2024	1.0	null
monolayer-surrounded lipid storage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
regulation of protein homooligomerization	GO Biological Process Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33106
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RB-34-TO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33261
AA-62-HP31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226278
betacells	GeneRIF Biological Term Annotations	1.0	null
parahippocampal gyrus, right, bank of the cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.9702
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05703
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13225
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831467
Cephalothorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7879
BRD-K62369921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37638
PMC7139457__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53276
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
DF-92-CF17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252674
PMC2533023__F5	PFOCR Pathway Figure Associations 2024	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.152
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX8_SOX8	Rummagene Transcription Factor Associations 2026	1.0	null
ascariasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174093
BRD-A55025683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0858
fluorometholone-5771	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10809641-DataSheet3.pdf-164-HOXD11_HOXD11	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2274
Myeloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
lm5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
NCI-H69 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
PK-59 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
used	GeneRIF Biological Term Annotations	1.0	null
BRD-K28983467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79218
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.24576
Perturb_17686_OE_HSD17B1_SRP366068	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.9926
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
Glioblastoma multiforme cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
Plastid intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.2133
BRD-K52669647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33428
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88777_0_v_1_cnot7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135976
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56364
cutaneous t cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.135605
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.719
lung epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.16759
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26784
Insulinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15825
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.848
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
encoding	GeneRIF Biological Term Annotations	1.0	null
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K36764776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54755
GSE158834_11_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
salpingitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.688692
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0421
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.103108
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14207
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424963
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.03987
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.605107
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898768
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hel	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37344
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34158
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44513
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29728947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29553
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4667_KO_Setd5_ERP110684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.52074
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046084
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.199
AA-14-VK39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314705
PMC9377669-tx1c00392_si_002.xlsx-DPH-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4267
BRD-K16943897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74192
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3262
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
HSF1	MotifMap Predicted Transcription Factor Targets	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045417
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22702
Perturb_1311_KO_Cntnap4_SRP386887	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.12352
Perturb_1283_KD_TRIM26_ERP131496	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K45073068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22543
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARH-77 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
JARID2-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Sucralose-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19132
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.51755
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203167
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
peptides	GeneRIF Biological Term Annotations	1.0	null
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71392
BRD-K00263786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35921
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052626
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.611
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06237859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.116
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11092745-media-2.xlsx-cGEP_Associated_Genes_Ranked-SOX4_TOX2_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-1126-SM-4KKZQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77432
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28518
Tetrachlorodibenzodioxin	CTD Gene-Chemical Interactions	1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.11999
ldr8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.821
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24804
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070417
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848213
Brain Diseases	CTD Gene-Disease Associations	1.0	1.39785
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188766
GSE218060_7_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.673
PMC4082364-supp_ddu111_ddu111supp_table9.xls-Tabelle1-Table_S9_MSC_WT1Wilms3_-_top_100_genes_down-regulated_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8276
BRD-K83095019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07432
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449116
PMC5543083-41467_2017_268_MOESM5_ESM.xlsx-Interactions_in_E2F1_map-Unnamed_2_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Kaposi's sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
U-373MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
RCOR3	ChEA Transcription Factor Targets	1.0	null
SUDHL6	CCLE Cell Line Gene Expression Profiles	1.0	1.75723
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95459450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47909
Phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.019
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21921
gastric	GeneRIF Biological Term Annotations	1.0	null
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64318
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12842
BRD-K72430479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11413
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.40985
BRD-A74152721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05256
BRD-K58193973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7143
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.682871
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.799
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tentative	GeneRIF Biological Term Annotations	1.0	null
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
proapoptotic	GeneRIF Biological Term Annotations	1.0	null
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863517
Fatigue	CTD Gene-Disease Associations	1.0	1.1786
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69387464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14827
BRD-K02159791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4381
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4184
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96052
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
NACC1	ChEA Transcription Factor Targets	1.0	null
Perturb_4991_KO_Mettl5_SRP268611	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.74053
pumabbc3	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10537
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3872
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
BRD-A32128687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21836
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K64356525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08646
DBTRG05MG	Achilles Cell Line Gene Essentiality Profiles	1.0	1.7795
mature t-cell and nk-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.120332
PMC9377669-tx1c00392_si_002.xlsx-Famotidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7363
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055276
BRD-K89532826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22633
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
BRD-K52924481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11358
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043876
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.283655
RT112	DepMap CRISPR Gene Dependency	1.0	2.02598
BB-23-PM31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294514
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.122
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10266
Mitochondrial Diseases	CTD Gene-Disease Associations	1.0	1.1977
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.192423
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35389
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21549
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69751
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
coelom	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186241
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1393_KO_Rad9_SRP214104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.41131
cellular	GeneRIF Biological Term Annotations	1.0	null
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Neuroepithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FC-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14907323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04275
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
Substance Withdrawal Syndrome	CTD Gene-Disease Associations	1.0	1.09083
TD-17-NF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.615981
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.30421
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.383637
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44815
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58595
YA-44-LW45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30534
B-cell chronic lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
abnormal autonomic nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
Anorexia	CTD Gene-Disease Associations	1.0	1.44517
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X4-01A-51R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62515
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
T-cell non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181525
BRD-K83276573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84227
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_JARID2_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.79596
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51619
Vision Disorders	CTD Gene-Disease Associations	1.0	1.14064
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10936
BRD-K03855997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47822
PMC4521181-oncsis201520x8.pdf-131-SETBP1_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69155
BRD-K36764343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60382
bh3	GeneRIF Biological Term Annotations	1.0	null
BRD-A42433574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13856
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
BRD-K36691793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54984
positive regulation of cellular component biogenesis	GO Biological Process Annotations 2015	1.0	null
EFE184	DepMap CRISPR Gene Dependency	1.0	2.03024
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23027
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054189
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K48556518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45561
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.29595
KB-00-DM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.335
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051439
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05737
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46838
GTEX-SUCS-1126-SM-4DM61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Longissimus capitis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844618
Neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.912759
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18139667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15537
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-30	GDSC Cell Line Gene Expression Profiles	1.0	1.45982
acute salpingitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.01638
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE70499_4_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244072_4_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRB-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Mitochondrial crista	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.03
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82907
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.214297
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
BRD-K36464765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35562
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57251296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06111
OCI-AML3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224579
BCL2	Pathway Commons Protein-Protein Interactions	1.0	null
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8041
YY1	ChEA Transcription Factor Targets	1.0	null
BRD-K02471501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50028
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67256
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.815
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.07848
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05315
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26414
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11145
NMuMg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911069
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23657
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970847
TRIM28	ChEA Transcription Factor Targets	1.0	null
lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092006
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35922
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primitive neuroectodermal tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31641
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23473
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.988626
BRD-K56645451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51697
EXTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79036
Coma	CTD Gene-Disease Associations	1.0	1.08231
nfe2l2_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.009121
PMC7396444__F4	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K74091626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88667
PMC6023766__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52005
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10144
microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196064
PMC6718311__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Fatty Liver, Alcoholic	CTD Gene-Disease Associations	1.0	1.08019
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27561
PMC7349719__F6	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K48299239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14535
PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_30min_vs_Control-Unnamed_1_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
KM12	CCLE Cell Line Gene CNV Profiles	1.0	1.37078
BRD-K18176829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49178
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-DDIT3_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
rituximab_homo sapiens_gpl570_gds3829	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.018
dp5	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37379
BRD-K22949587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26359
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94932
LU99	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878882
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-378g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12281
SRY	ChEA Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7XN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15816
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.491
SPEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76301
hypopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449116
Follicular lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053761
CD-97-ZV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318538
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0367
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Liver Failure	CTD Gene-Disease Associations	1.0	1.10388
positive regulation of programmed cell death	GO Biological Process Annotations 2023	1.0	null
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67964
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.9735
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5657403__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K28927944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77135
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930232
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241132
BRD-K90360779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42055
Dentate gyrus granule cell layer volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.50458
halcinonide-7379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0526-SM-4BOPS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11408
BRD-K05086663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3976
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNU213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33276
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42174
JHESOAD1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.2437
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K96120749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02201
Cavum septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8145
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
Epithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
prostate	GeneRIF Biological Term Annotations	1.0	null
BRD-K98239824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02769
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18228
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13508
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9811
Host extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.035
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.38966
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41906
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.693
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.383637
MYC-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6023766__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Burkitt lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
t-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.332294
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
DF-26-EY87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263994
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82568
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
non-Hodgkin lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
positive regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
BRD-K69350885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19435
Perturb_8632_KO_Sh3gl1/Sh3gl2/Sh3gl3_SRP082219	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.4027
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.33741
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.516
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HD-18-YL30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22957
BRD-K13241788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8504
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516891
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6883
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
19838208-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997488
BRD-K39029546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41765
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12984952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00966
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7239
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66985689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18308
KM-H2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
ATF-2 transcription factor network	PID Pathways	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WW-01A-22R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute salpingitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
triamcinolone-7192	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tremor	CTD Gene-Disease Associations	1.0	1.02671
GSE224004,GSE224005_0_v_6_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10692
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37038
EBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27756
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910607
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.823
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03902845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43941
Lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.741
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45086
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-89-DG86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216411
bladder	GTEx Tissue Gene Expression Profiles	-1.0	-0.964592
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-hodgkin lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187776
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
transcripts	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875796
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17266
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82673
Amyloplast starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.206
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7531772__F5	PFOCR Pathway Figure Associations 2023	1.0	null
PMC2712786__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K09250623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94559
HERPUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71962
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.0476
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7050-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111035,GSE111040_8_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
phi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
LU-99A	GDSC Cell Line Gene Expression Profiles	1.0	2.23788
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868317
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3674
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_TUBA1A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
proliferation	GeneRIF Biological Term Annotations	1.0	null
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.20169
chronic salpingitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.997392
parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062606
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28248
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07023
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61441533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.531
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42911
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65512
IKZF2_01_137	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.44171
MM1S	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44341
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042525
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14246_KO_FOXM1_SRP328179	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
phensuximide-5097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6527025__F2	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9095
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of protein-containing complex assembly	GO Biological Process Annotations 2023	1.0	null
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28725
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Perturb_4422_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.878
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14594
SNU1066	CCLE Cell Line Gene Expression Profiles	1.0	1.67391
EZH2	ChEA Transcription Factor Targets	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01615
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063899
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239007
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
B95-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
PMC9377669-tx1c00392_si_002.xlsx-Teriflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	2.12132
BRD-K45712538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05893
BRD-K11844807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70373
MAFK	ENCODE Transcription Factor Targets	1.0	null
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
cinchonidine-7190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
16449190-Table1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
DAUDI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
PARP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41533
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.742638
CRCGN012_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19401
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PMC4836210__F7	PFOCR Pathway Figure Associations 2024	1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.474922
u698	HPA Cell Line Gene Expression Profiles	1.0	1.47171
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.503
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23978
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12984
PUMA-BCL-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02749
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890381
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12788
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3414384__F1	PFOCR Pathway Figure Associations 2023	1.0	null
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.478668
BRD-K13146924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41891
BF-89-QD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212432
fendiline-7188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BAX complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.275
LbetaT2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
hsa-miR-4495	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
BRD-K76713927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41936
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887545
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63195
TP63_01_196	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5869
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57557
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.13
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Ascospore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.9494
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.703
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6044101__F6	PFOCR Pathway Figure Associations 2023	1.0	null
PMC7899648-elife-61630-supp2.xlsx-Blad1-Subset_of_TFE3_targets_upregulated_in_FLCNNEG_RPTEC_cluster_3_boxed_yellow_in_Figure_3A_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07876
liver	GTEx Tissue Gene Expression Profiles	-1.0	-2.09514
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.994
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34688
t93	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
PMC7349719__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K01772946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10847
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193728
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20261
REH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
PMC6718311__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GSE211151_2_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.4
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43765
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
BRD-K56106571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15743
RAD21	ENCODE Transcription Factor Targets	1.0	null
Drug Hypersensitivity	CTD Gene-Disease Associations	1.0	1.34082
BRD-K48195722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68487
apoptosis	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98465548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72361
Bcl-2 family protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.365
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
malignancies	GeneRIF Biological Term Annotations	1.0	null
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08841
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.47
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34688
methylation	GeneRIF Biological Term Annotations	1.0	null
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lm1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
BRD-K59239976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1741
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1863
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05894
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094467
CHD1	ENCODE Transcription Factor Targets	1.0	null
mouse	GeneRIF Biological Term Annotations	1.0	null
ChIP_MYC_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Down_Regulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
NAMALWA	CCLE Cell Line Gene Expression Profiles	1.0	2.1571
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DU-4475	GDSC Cell Line Gene Expression Profiles	-1.0	-2.26085
BRD-K96416345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91746
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	0.846882
PMC8298376__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K53308623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.017
Peripheral Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.44982
endoplasmic	GeneRIF Biological Term Annotations	1.0	null
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.897
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14689
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vomiting	CTD Gene-Disease Associations	1.0	1.29502
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rhizophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70I-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16822_KD_Miat_SRP379156	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
necessary	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
jnkinduced	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04638
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16944
Testicular cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.414
positive regulation of release of cytochrome c from mitochondria	GO Biological Process Annotations 2023	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062411
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24532
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.84725
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A63382799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20683
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073698
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_6671_KO_KLB_SRP386785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-y_TFEB_KO_LLOMe_VS_WT_LLOMe_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49983
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.292897
SMAD3-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Solid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.34
T-cell acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC1716201__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64347
including	GeneRIF Biological Term Annotations	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00565
lung epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374618
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69776
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NALM6	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07432
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068393
pahs	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16763
16651409-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
BRD-K99404845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04739
PMC5530849__F4	PFOCR Pathway Figure Associations 2023	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tiotropium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03965
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063279
HDAC6	ENCODE Transcription Factor Targets	1.0	null
sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.140405
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24873
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Glioblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.088221
BRD-K60188481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14197
decreased cell death	MPO Gene-Phenotype Associations	1.0	null
B-lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
Lung squamous cell carcinoma_LUSC_TCGA-60-2696-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
programmed cell death	GO Biological Process Annotations 2015	1.0	null
BRD-K62148271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37367
pre-T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.484
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.677395
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46169
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MITF_01_25	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60275
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1184	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.1562
cytosolic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054438
thyroiditis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.237009
19838208-TableS3	GeneSigDB Published Gene Signatures	1.0	null
acute lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098813
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37781
precuneus, right, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98552
15459216-TableA2f	GeneSigDB Published Gene Signatures	1.0	null
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
16024939-Table2	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44166
Apoptosis regulator, Bcl-2, BH3 motif, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
ML-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55402
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurolemma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966563
AC-97-KP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.279651
hrk	GeneRIF Biological Term Annotations	1.0	null
Dehydrodolichyl diphosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.074
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076944
PMC7225374__F11	PFOCR Pathway Figure Associations 2024	1.0	null
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bendroflumethiazide-4315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51841
only	GeneRIF Biological Term Annotations	1.0	null
positive regulation of protein oligomerization	GO Biological Process Annotations 2015	1.0	null
BRD-K77343050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13082
dilazep-7364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_15650_OE_Trim59_SRP229490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11784
Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K20009653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94862
Tuberous root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52118
u-266 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.370496
BRD-K33204113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06292
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
PUMA-BCL-xl complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.126
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.37576
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE218060_1_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K38131403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27588
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
BRD-K17171256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02025
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.37396
alzheimer's disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
BRD-K59182232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10219
Perturb_3240_OE_IK6_SRP136156	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.7647
stat3_00000000_a549_lof_human_gpl571_gse42979	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.762378
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.11095
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGR37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74992
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WD-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8335161__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K38574421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06533
GSE70499_0_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04117
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart Failure	CTD Gene-Disease Associations	1.0	1.33464
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.47047
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46453
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28758
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43808
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.331391
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48427
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Perturb_17681_KO_Kdm4a_SRP101992	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.13399
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00256
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68853
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05973
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581618
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
hsa-miR-515-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03897
GABPA	ENCODE Transcription Factor Targets	1.0	null
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.91325
trigger	GeneRIF Biological Term Annotations	1.0	null
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27811
Chronic myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-Overlap-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8639975-41598_2021_98792_MOESM3_ESM.xlsx-S5_-_MEF2A_core_enriched-Unnamed_2_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248393
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.38375
JAK1_knockdown_160_GSE37012	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.71024
ASAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14942
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868862
BRD-K91277001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61959
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91725
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.643
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.264581
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.711729
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
pargyline-2102	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042328
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305001
KDM5A-27292631-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BA-28-XM73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267532
valproic acid-6929	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
Perturb_14505_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.05789
Paresthesia	CTD Gene-Disease Associations	1.0	1.13347
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.51922
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.43552
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827177
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05228
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04446
balb3t3clonea31	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.846
Leukemic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048646
Daphnid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Fungal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.75038
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00676
stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165421
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163282_12_v_5_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate	HPA Tissue Gene Expression Profiles	-1.0	-1.23042
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983252
BRD-K54505405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15352
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66282
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824353
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36737
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895307
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63375
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279367
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832187
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
MA-25-RP17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214365
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39048
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23131
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04505
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.63896
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6044101__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amorolfine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35912
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.61587
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.827
BRD-K94191869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02191
BRD-K44713204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0343
BRD-K19734887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16663
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.47
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8927
Arrhythmias, Cardiac	CTD Gene-Disease Associations	1.0	1.23552
HEC108	CCLE Cell Line Gene Expression Profiles	1.0	2.15411
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.519
BRD-K78315404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9658
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34472
bcl2	GeneRIF Biological Term Annotations	1.0	null
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Storage tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917315
hgf cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.835737
PMC11239940-44319_2024_164_MOESM1_ESM.pdf-22-LEF1-AS1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38963
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03825
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942642
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42508
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45331
CBX2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12146336-Data_Sheet_1.pdf-13-RHOXF1_RHOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03363
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.956223
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01275
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.096382
pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351114
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945779
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48126
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3522
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07648
GSE133213_10_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7432812__F2	PFOCR Pathway Figure Associations 2023	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211286_7_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-A80035237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12925
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K61522760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07478
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
16449190-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00251
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70499_4_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NE-00-JZ19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.417268
CA-66-FY97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206057
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.266
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
t-lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133791
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.12984
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21673
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.803
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovary cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.487
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	232.328
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0074
TRAIL death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.971654
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.20173
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MOLM-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27488
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
metergoline-5344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
16357179-Table2	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chronic gonococcal salpingitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.22562
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.326646
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926043
Leucoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0923
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fever	CTD Gene-Disease Associations	1.0	1.36791
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.696026
BRD-K00797068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44695
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.463488
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.131
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25928
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6773
ERG	ChEA Transcription Factor Targets	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.74113
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32277
multiple myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142832
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063804
BRD-K14306031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72328
Gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
Hippocampal tail volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.8699
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
CW-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60557
PTPRB	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43895
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal hypoglossal nerve morphology	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.718
FAM86B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36444
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye accommodation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.888
organelle envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.302912
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
prostate_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35472
msto-211h cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.72733
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6473
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.647956
Pancreatic islet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.792
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
bromocriptine-1507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24088
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20019
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26395018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03958
pbmc cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330827
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30264389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00047
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02241
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10213
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-1.00332
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.945597
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58028568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62928
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null