association	dataset	threshold value	standardized value
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4176
AKR1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28876
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2366
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4485
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82039
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6542
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9407
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.833
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0671
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0379
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9529
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7962
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4375
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3287
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4982
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1596
NUDT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58209
GSE162623_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98131
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83103
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3961
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04149
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56498
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.003
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2121
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3959
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5977
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05964
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7439
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3579
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2701
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8234
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5224
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71315
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9926
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33538
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4
SOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09541
SPIN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18738
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0461
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4404
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60337
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7077
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9312
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.597
KIFBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42997
FAM234A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8363
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78201
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2841
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3511
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6752
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3148
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8518
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5169
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.535
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3865
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2087
SMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30763
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8898
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4117
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8078
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Chromatin	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4545
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6904
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57434
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0392
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3792
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81917
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1065
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3949
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03287
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6632
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2727
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47517
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.48
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7197
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5057
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2067
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0947
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18736
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26008
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2547
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8053
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61137
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.909
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0815
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5683
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1062
NACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56753
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9916
SHKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28904
ZNF417	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94846
PHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27313
HEY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26964
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.347
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6042
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8527
ZNF784	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96256
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8657
HOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4231
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9898
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71501
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.186
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7945
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9792
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3967
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0448
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0356
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00474
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4575
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4594
CHMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28634
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7685
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2281
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.9753
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11062
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2114
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0968
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0281
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8634
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6463
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0116
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2819
IFITM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51825
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8566
ANO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7162
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1633
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8549
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2236
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1189
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2799
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7983
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7245
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.436
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.395
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6039
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4385
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3488
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893