association	dataset	threshold value	standardized value
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3276
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3164
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3322
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46276
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.708
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3611
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6213
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0634
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5625
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2029
GSE144500_8_v_11_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0148
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4213
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5752
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8189
GSE190950_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mucopolysaccharidosis I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-445-HSFX1_HSFX1	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8702
Mucopolysaccharidosis II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13008
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8271
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3065
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.942
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0907
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
TMEM41A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99052
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74561
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lattice corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8947
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0064
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.295
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7192
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9229
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6183
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1373
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.532
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5018
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7806
TK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20544
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4494
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0774
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2751
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5676
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1774
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6957
PGBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36879
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4469
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-894-ENSG00000171116_HSFX1	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5668
SLC25A24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65729
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84766
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3826
Corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9879
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2172
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.1703
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96034
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1846
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.465
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5833
GSE185865_0_v_1_celf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193541_0_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4036
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44733
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79216
TSPAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00599
NDUFAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63265
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.877
NUDT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68156
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6696
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2132
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.98
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25941
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6574
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3015
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4267
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3014
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6136
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8898
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7512
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5753
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0657
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.5847
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4321
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1613
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83765
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3316
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6591
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3317
SFXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85499
epithelial-stromal TGFBI dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gbm cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
PMC8948606-7488708.f2.docx-6-PRDM12_PRDM12	Rummagene Transcription Factor Associations 2026	1.0	null
ORMDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43218
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9722
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16545
Umbilical hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4814
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.298
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1257
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3073
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8026
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44561
Mucopolysaccharidosis Ih	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5297
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0014
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46968
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85796
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34936
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83096
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3409
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79562
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.784
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205913_1_v_0_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.8493
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6259
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42463
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4422
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1219
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0326
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7649
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2831
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.06194
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9937
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6964
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8708
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8248
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7557
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99235