association	dataset	threshold value	standardized value
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4522
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863102
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10626
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
SLC25A24	Pathway Commons Protein-Protein Interactions	1.0	null
PABPC3	Pathway Commons Protein-Protein Interactions	1.0	null
SR 142948	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
ATP4A	Pathway Commons Protein-Protein Interactions	1.0	null
2,6-Dichlorophenethylamine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839078
IKBIP	Pathway Commons Protein-Protein Interactions	1.0	null
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB8	Pathway Commons Protein-Protein Interactions	1.0	null
HLE	CCLE Cell Line Gene CNV Profiles	1.0	1.39287
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
ILKAP	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH854	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36305
PLCPRF5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40208
PLAA	Pathway Commons Protein-Protein Interactions	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HCoV-EMC2012_24Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.952837
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949155
ERGIC3	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA1	Pathway Commons Protein-Protein Interactions	1.0	null
AP3B1	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA2	Pathway Commons Protein-Protein Interactions	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26496
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966562
CSDE1	Pathway Commons Protein-Protein Interactions	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00981
ATP2B3	Pathway Commons Protein-Protein Interactions	1.0	null
PAICS	Pathway Commons Protein-Protein Interactions	1.0	null
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
TNPO1	Pathway Commons Protein-Protein Interactions	1.0	null
A 438079	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
Aripiprazole	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
STK235555	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
KIAA0196	Pathway Commons Protein-Protein Interactions	1.0	null
SARS-CoV_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.03096
SLC7A5	Pathway Commons Protein-Protein Interactions	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.972337
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.718
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.93187
CBIO	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.59
IDH1	Pathway Commons Protein-Protein Interactions	1.0	null
PRKACB	Pathway Commons Protein-Protein Interactions	1.0	null
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
HS766T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34167
KHSRP	Pathway Commons Protein-Protein Interactions	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95752
PPP2R2A	Pathway Commons Protein-Protein Interactions	1.0	null
APEH	Pathway Commons Protein-Protein Interactions	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27145
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
CSTF3	Pathway Commons Protein-Protein Interactions	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.86191
Lalistat1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.55
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24547
CAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Pramipexole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
RBBP5	ENCODE Transcription Factor Targets	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02648
CAT	Pathway Commons Protein-Protein Interactions	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63057
GALK1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.0119
DP-agonist13	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11202
Abiraterone2	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23269
PFKL	Pathway Commons Protein-Protein Interactions	1.0	null
QARS	Pathway Commons Protein-Protein Interactions	1.0	null
IMPDH2	Pathway Commons Protein-Protein Interactions	1.0	null
HMB-Val-Ser-Leu-VE	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.42
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
AARS	Pathway Commons Protein-Protein Interactions	1.0	null
Paliperidone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
TUBAL3	Pathway Commons Protein-Protein Interactions	1.0	null
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
BAG6	Pathway Commons Protein-Protein Interactions	1.0	null
ACTN1	Pathway Commons Protein-Protein Interactions	1.0	null
LPCAT2	Pathway Commons Protein-Protein Interactions	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.15446
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
FAF2	Pathway Commons Protein-Protein Interactions	1.0	null
MYO1E	Pathway Commons Protein-Protein Interactions	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910771
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00121
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65695
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20901
IDH2	Pathway Commons Protein-Protein Interactions	1.0	null
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842893
XRCC4	Pathway Commons Protein-Protein Interactions	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86248
INT-747	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.11499
SCYL1	Pathway Commons Protein-Protein Interactions	1.0	null
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36539
PPP2CB	Pathway Commons Protein-Protein Interactions	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898701
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11354
3-Benzyloxyaniline	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.67098
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GNAT3	Pathway Commons Protein-Protein Interactions	1.0	null
ADRBK1	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35247
DHCR7	Pathway Commons Protein-Protein Interactions	1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	2.73741
EIF4G1	Pathway Commons Protein-Protein Interactions	1.0	null
ATP2B2	Pathway Commons Protein-Protein Interactions	1.0	null
BV-173	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.49563
ATL3	Pathway Commons Protein-Protein Interactions	1.0	null
no-11	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.9793
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825482
PSMD1	Pathway Commons Protein-Protein Interactions	1.0	null
TMPO	Pathway Commons Protein-Protein Interactions	1.0	null
AHCY	Pathway Commons Protein-Protein Interactions	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07069
ACTG1	Pathway Commons Protein-Protein Interactions	1.0	null
SMARCB1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23232
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885432
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84384
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29665
WDR77	Pathway Commons Protein-Protein Interactions	1.0	null
AGN 190299	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
AFG3L2	Pathway Commons Protein-Protein Interactions	1.0	null
SK-MES-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.87469
FAM129A	Pathway Commons Protein-Protein Interactions	1.0	null
6603-0104	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
NOMO1	Pathway Commons Protein-Protein Interactions	1.0	null
Anastrozole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.65
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839078
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60459
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.83978
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44206
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49082
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24547
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49533
PLS3	Pathway Commons Protein-Protein Interactions	1.0	null
SFXN3	Pathway Commons Protein-Protein Interactions	1.0	null
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
ADRBK2	Pathway Commons Protein-Protein Interactions	1.0	null
Undecanoic acid	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4072
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27145
PSMD13	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
ITGB2	Pathway Commons Protein-Protein Interactions	1.0	null
KIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
SNU216	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46693
TM31	CCLE Cell Line Gene CNV Profiles	1.0	2.38845
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
Gandotinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.87
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLS1	Pathway Commons Protein-Protein Interactions	1.0	null
PABPC4	Pathway Commons Protein-Protein Interactions	1.0	null
SPIB	JASPAR Predicted Transcription Factor Targets	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01512
UACC-257	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.06968
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835127
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1644
H3K9me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LARS	Pathway Commons Protein-Protein Interactions	1.0	null
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18598
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
SMI-16a	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
GARS	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
EIF3H	Pathway Commons Protein-Protein Interactions	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1581
PDHB	Pathway Commons Protein-Protein Interactions	1.0	null
HSP90AA2	Pathway Commons Protein-Protein Interactions	1.0	null
NRD1	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82678
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.914517
CAL851	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52262
HER2_OE_GDS4763_331_human_MCF10A - immortalized breast epithelial cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SERPINB8	Pathway Commons Protein-Protein Interactions	1.0	null
Torcetrapib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.47
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12106
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.984146
SH3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00088
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08069
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835127
MYO1F	Pathway Commons Protein-Protein Interactions	1.0	null
Erythromycin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
ALDH2	Pathway Commons Protein-Protein Interactions	1.0	null
PPP1CB	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
POLD1	Pathway Commons Protein-Protein Interactions	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40577
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20265
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CPSF6	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-150	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.29138
DG-75	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.51561
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888067
TIMM50	Pathway Commons Protein-Protein Interactions	1.0	null
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60312
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916545
OGDH	Pathway Commons Protein-Protein Interactions	1.0	null
SUN2	Pathway Commons Protein-Protein Interactions	1.0	null
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
SBC-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.78212
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37745
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Metolazone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
Tropicamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.42
ATP2A3	Pathway Commons Protein-Protein Interactions	1.0	null
GNA13	Pathway Commons Protein-Protein Interactions	1.0	null
SART3	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disordered domain specific binding	GO Molecular Function Annotations 2023	1.0	null
viral infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
HEC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88111
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52618
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.3278
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19491
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966562
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA3	Pathway Commons Protein-Protein Interactions	1.0	null
Forodesine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.54
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
IPO8	Pathway Commons Protein-Protein Interactions	1.0	null
IKBKG	Pathway Commons Protein-Protein Interactions	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01681
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29583
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47665
SCCPDH	Pathway Commons Protein-Protein Interactions	1.0	null
ELMO2	Pathway Commons Protein-Protein Interactions	1.0	null
USP15	Pathway Commons Protein-Protein Interactions	1.0	null
10074-G5	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24547
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.828152
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881804
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
PPP1CC	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898701
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39009
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.01799
EoL-1-cell	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.77206
VCP	Pathway Commons Protein-Protein Interactions	1.0	null
HPGDS-In1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.7
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08069
PDIA6	Pathway Commons Protein-Protein Interactions	1.0	null
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
SLC1A5	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65695
M07E	CCLE Cell Line Gene CNV Profiles	1.0	1.41607
Binospirone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28176
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23232
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75646
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2327
ATP1A2	Pathway Commons Protein-Protein Interactions	1.0	null
ATP binding	GO Molecular Function Annotations 2023	1.0	null
SQRDL	Pathway Commons Protein-Protein Interactions	1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	1.59387
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881804
UBA7	Pathway Commons Protein-Protein Interactions	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71414
BLZ-945	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
MARS	Pathway Commons Protein-Protein Interactions	1.0	null
A-CA-04-2009(H1N1)_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.47744
PSMD12	Pathway Commons Protein-Protein Interactions	1.0	null
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
HL-60	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.97177
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
ATXN10	Pathway Commons Protein-Protein Interactions	1.0	null
COPG2	Pathway Commons Protein-Protein Interactions	1.0	null
RNPEP	Pathway Commons Protein-Protein Interactions	1.0	null
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.83811
SRPR	Pathway Commons Protein-Protein Interactions	1.0	null
SKNAS	CCLE Cell Line Gene CNV Profiles	1.0	1.67644
Prinomastat	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
H3K9me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949155
ACOT8	Pathway Commons Protein-Protein Interactions	1.0	null
PDHA1	Pathway Commons Protein-Protein Interactions	1.0	null
Balicatib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
NCIH2141	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6598
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82678
IPO5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07522
PTK2B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.984619
PEER	CCLE Cell Line Gene CNV Profiles	1.0	1.50404
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42552
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72135
DARS	Pathway Commons Protein-Protein Interactions	1.0	null
ALDH1L2	Pathway Commons Protein-Protein Interactions	1.0	null
ATAD3C	Pathway Commons Protein-Protein Interactions	1.0	null
adenyl ribonucleotide binding	GO Molecular Function Annotations 2023	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18428
FAM49B	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15941
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
BUB3	Pathway Commons Protein-Protein Interactions	1.0	null
CUL4B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72598
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51233
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.72558
nucleus	GO Cellular Component Annotations 2023	1.0	null
BRE	Pathway Commons Protein-Protein Interactions	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37788
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.850192
COLGALT1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02648
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849871
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.55233
ATP1A3	Pathway Commons Protein-Protein Interactions	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3327
KIF5C	Pathway Commons Protein-Protein Interactions	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	1.76488
DHCR24	Pathway Commons Protein-Protein Interactions	1.0	null
SURF4	Pathway Commons Protein-Protein Interactions	1.0	null
OACp4C	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.04672
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881804
IPO9	Pathway Commons Protein-Protein Interactions	1.0	null
COLO-679	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.04553
PSMC4	Pathway Commons Protein-Protein Interactions	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	2.12141
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63621
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.41338
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28176
NCI-H2795	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.72687
EIF3B	Pathway Commons Protein-Protein Interactions	1.0	null
A-CA-04-2009(H1N1)_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.60155
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.15446
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00214
CARS	Pathway Commons Protein-Protein Interactions	1.0	null
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08069
NP118809	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
CUL4A	Pathway Commons Protein-Protein Interactions	1.0	null
CDK9_knockdown_71_GSE21751	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	3.73063
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842893
DNM1	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898701
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	2.55256
UBA1	Pathway Commons Protein-Protein Interactions	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20901
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	2.08881
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57879
TUBB1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMAN2	Pathway Commons Protein-Protein Interactions	1.0	null
HSP90AB4P	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD11	Pathway Commons Protein-Protein Interactions	1.0	null
M6PR	Pathway Commons Protein-Protein Interactions	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18598
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20743
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
SLC25A13	Pathway Commons Protein-Protein Interactions	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
Marimastat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.59
EZH2	ENCODE Transcription Factor Targets	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2429
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910771
ATP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
JHH-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.71145
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PRR4	Pathway Commons Protein-Protein Interactions	1.0	null
FDFT1	Pathway Commons Protein-Protein Interactions	1.0	null
NCKAP1L	Pathway Commons Protein-Protein Interactions	1.0	null
Purvalanol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
DDOST	Pathway Commons Protein-Protein Interactions	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.51208
NCSTN	Pathway Commons Protein-Protein Interactions	1.0	null
MOGS	Pathway Commons Protein-Protein Interactions	1.0	null
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54036
Acitretin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.5
CTPS2	Pathway Commons Protein-Protein Interactions	1.0	null
ZMPSTE24	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB4A	Pathway Commons Protein-Protein Interactions	1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.02127
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
OGDHL	Pathway Commons Protein-Protein Interactions	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17124
GMPS	Pathway Commons Protein-Protein Interactions	1.0	null
TECR	Pathway Commons Protein-Protein Interactions	1.0	null
NR2E1_01_306	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65065
TE9	CCLE Cell Line Gene CNV Profiles	1.0	1.93024
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2429
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09311
GNAO1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.057922
DNAJA2	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HX 531	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.07
HuCCT1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.15423
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13426
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01624
MTA2	Pathway Commons Protein-Protein Interactions	1.0	null
NKM-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.48975
uterus	GTEx Tissue Gene Expression Profiles	1.0	0.829465
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-1.15446
SF3A1	Pathway Commons Protein-Protein Interactions	1.0	null
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
RNH1	Pathway Commons Protein-Protein Interactions	1.0	null
ATP1A1	Pathway Commons Protein-Protein Interactions	1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01876
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910771
Esmolol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
CAPZA1	Pathway Commons Protein-Protein Interactions	1.0	null
PLOD1	Pathway Commons Protein-Protein Interactions	1.0	null
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
L-168,049	DeepCoverMOA Drug Mechanisms of Action	1.0	0.45
OE19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32714
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
UBE3C	Pathway Commons Protein-Protein Interactions	1.0	null
GFPT1	Pathway Commons Protein-Protein Interactions	1.0	null
Sildenafil	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.42
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.7406
HSP90AB2P	Pathway Commons Protein-Protein Interactions	1.0	null
HEATR3	Pathway Commons Protein-Protein Interactions	1.0	null
Fumitremorgin C	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00214
acquired immunodeficiency syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
ESYT2	Pathway Commons Protein-Protein Interactions	1.0	null
SARS-CoV_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.8195
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24432
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.972337
Tolimidone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
GNAL	Pathway Commons Protein-Protein Interactions	1.0	null
AIMP1	Pathway Commons Protein-Protein Interactions	1.0	null
TNPO2	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DANG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61826
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3327
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37788
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
SEC23B	Pathway Commons Protein-Protein Interactions	1.0	null
Atosiban	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05278
Bromfenac	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
PPT1	Pathway Commons Protein-Protein Interactions	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12943
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48489
FAR1	Pathway Commons Protein-Protein Interactions	1.0	null
HA130	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
TE-10	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.94416
human immunodeficiency virus infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916879
MCM4	Pathway Commons Protein-Protein Interactions	1.0	null
RRM1	Pathway Commons Protein-Protein Interactions	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01512
disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
ALAD	Pathway Commons Protein-Protein Interactions	1.0	null
cellular response to heat	GO Biological Process Annotations 2023	1.0	null
LPCAT1	Pathway Commons Protein-Protein Interactions	1.0	null
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
RCC-ER	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.11664
DNAJC9	Pathway Commons Protein-Protein Interactions	1.0	null
ATAD1	Pathway Commons Protein-Protein Interactions	1.0	null
AP1B1	Pathway Commons Protein-Protein Interactions	1.0	null
Her2_OE_GSE43730_683_human_MCF10A cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
IARS	Pathway Commons Protein-Protein Interactions	1.0	null
HARS	Pathway Commons Protein-Protein Interactions	1.0	null
SEC63	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
OLA1	Pathway Commons Protein-Protein Interactions	1.0	null
OPLAH	Pathway Commons Protein-Protein Interactions	1.0	null
PCI-4B	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.95557
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13084
EIF4A2	Pathway Commons Protein-Protein Interactions	1.0	null
CNOT10	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55909
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.984146
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
PPA2	Pathway Commons Protein-Protein Interactions	1.0	null
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35739
XPO1	Pathway Commons Protein-Protein Interactions	1.0	null
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
LOMEGUATRIB	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGAP4	Pathway Commons Protein-Protein Interactions	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.83473
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910771
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33025
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
UQCRC2	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1568	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52994
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
ESYT1	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K9me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Olanzapine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
PSMC5	Pathway Commons Protein-Protein Interactions	1.0	null
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09283
CPT1A	Pathway Commons Protein-Protein Interactions	1.0	null
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27145
RS4-11	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.08936
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57879
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11354
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.9573
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903673
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23627
RARS	Pathway Commons Protein-Protein Interactions	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88837
CYFIP2	Pathway Commons Protein-Protein Interactions	1.0	null
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.95266
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05013
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23168
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.93251
GNA12	Pathway Commons Protein-Protein Interactions	1.0	null
NNC 26-9100	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.06
SU8686	CCLE Cell Line Gene CNV Profiles	1.0	1.39069
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.922883
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.45751
H3K9me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDC37	Pathway Commons Protein-Protein Interactions	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.857571
CYFIP1	Pathway Commons Protein-Protein Interactions	1.0	null
G-402	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.93117
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
NALM-6	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.9386
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
Varespladib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57879
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23499
BFTC-905	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.00544
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
VARS	Pathway Commons Protein-Protein Interactions	1.0	null
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.37384
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43491
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.913484
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD3	Pathway Commons Protein-Protein Interactions	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.79943
UPF 648	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
sirolimus_homo sapiens_gpl6244_gse15703	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03956
Sulfanilamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0578
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.986337
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
PFKP	Pathway Commons Protein-Protein Interactions	1.0	null
GW7647	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
ARHGEF7	Pathway Commons Protein-Protein Interactions	1.0	null
FAM105A	Pathway Commons Protein-Protein Interactions	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2023	1.0	null
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Trihydroxyisoflavone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
ZD 7288	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
CORO7	Pathway Commons Protein-Protein Interactions	1.0	null
TRIP13	Pathway Commons Protein-Protein Interactions	1.0	null
Tanomastat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
SCC25	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45512
PRKACA	Pathway Commons Protein-Protein Interactions	1.0	null
SLC25A12	Pathway Commons Protein-Protein Interactions	1.0	null
Chlorsulfuron	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34018
PSMD7	Pathway Commons Protein-Protein Interactions	1.0	null
CTPS1	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1339	CCLE Cell Line Gene CNV Profiles	1.0	1.76473
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953227
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66255
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888341
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842893
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25616
ABCD1	Pathway Commons Protein-Protein Interactions	1.0	null
CSE1L	Pathway Commons Protein-Protein Interactions	1.0	null
protein stabilization	GO Biological Process Annotations 2023	1.0	null
PSMD14	Pathway Commons Protein-Protein Interactions	1.0	null
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
CNOT3	Pathway Commons Protein-Protein Interactions	1.0	null
Clozapine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.42
ATP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
CAPN2	Pathway Commons Protein-Protein Interactions	1.0	null
LANCL1	Pathway Commons Protein-Protein Interactions	1.0	null
OCILY3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95661
WM1799	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36291
NCI-H2052	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.45206
SKM-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.41299
TARS	Pathway Commons Protein-Protein Interactions	1.0	null
Benzbromarone	DeepCoverMOA Drug Mechanisms of Action	1.0	1.56
QX 314	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
ATP1A4	Pathway Commons Protein-Protein Interactions	1.0	null
BZW2	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984798
UT7	CCLE Cell Line Gene CNV Profiles	1.0	1.53616
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916879
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
SSR 69071	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
CHI3L1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18643
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49673
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06487
PRMT5	Pathway Commons Protein-Protein Interactions	1.0	null
Basimglurant	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
ATP2B4	Pathway Commons Protein-Protein Interactions	1.0	null
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
CNOT11	Pathway Commons Protein-Protein Interactions	1.0	null
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-12-BM	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.01073
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46893
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33229
DOCK8	Pathway Commons Protein-Protein Interactions	1.0	null
LRRC8C	Pathway Commons Protein-Protein Interactions	1.0	null
Crizotinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.79
PSMC6	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H810	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.82155
SW780	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.28294
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48977
PAP-1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12311
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05989
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60721
GFPT2	Pathway Commons Protein-Protein Interactions	1.0	null
IPO7	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.237
CARD9	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1D	Pathway Commons Protein-Protein Interactions	1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866948
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10626
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GART	Pathway Commons Protein-Protein Interactions	1.0	null
VDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
Ca-Ski	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.65359
EIF3F	Pathway Commons Protein-Protein Interactions	1.0	null
ACLY	Pathway Commons Protein-Protein Interactions	1.0	null
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46768
PSMD6	Pathway Commons Protein-Protein Interactions	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	2.08856
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888341
HAT1	Pathway Commons Protein-Protein Interactions	1.0	null
SNU840	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7819
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40416
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
ALDH18A1	Pathway Commons Protein-Protein Interactions	1.0	null
KTN1	Pathway Commons Protein-Protein Interactions	1.0	null
LCP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DNM3	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
PF 04447943	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24472
KCTD12	Pathway Commons Protein-Protein Interactions	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29583
AGPAT5	Pathway Commons Protein-Protein Interactions	1.0	null
NB4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.86309
ELK3_01_318	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59784
IKBKB	Pathway Commons Protein-Protein Interactions	1.0	null
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50735
786O	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90016
FAM49A	Pathway Commons Protein-Protein Interactions	1.0	null
CLGN	Pathway Commons Protein-Protein Interactions	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1644
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.873167
AUDA	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.44
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.984146
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.892362
DNAJA1	Pathway Commons Protein-Protein Interactions	1.0	null
ADK	Pathway Commons Protein-Protein Interactions	1.0	null
SLC3A2	Pathway Commons Protein-Protein Interactions	1.0	null
EIF4G3	Pathway Commons Protein-Protein Interactions	1.0	null
Terazosin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
Huperzine A	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
bladder	GTEx Tissue Gene Expression Profiles	1.0	1.52759
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96883
CTCF	ENCODE Transcription Factor Targets	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83508
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55909
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29583
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39421
FKBP8	Pathway Commons Protein-Protein Interactions	1.0	null
MCM6	Pathway Commons Protein-Protein Interactions	1.0	null
SARS-BatSRBD_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.31062
SNU182	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68453
EIF3D	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8135
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842893
TPP1	Pathway Commons Protein-Protein Interactions	1.0	null
DLST	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACTN3	Pathway Commons Protein-Protein Interactions	1.0	null
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
ATP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DPYSL2	Pathway Commons Protein-Protein Interactions	1.0	null
HEL	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.22018