association	dataset	threshold value	standardized value
PELP1	Pathway Commons Protein-Protein Interactions	1.0	null
YWHAB	Pathway Commons Protein-Protein Interactions	1.0	null
PRICKLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45007
EIF3E	Pathway Commons Protein-Protein Interactions	1.0	null
GSE90821_3_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K13627844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76922
SENP3	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FC-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525336
A549_FLLL32_1µM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139874
Perturb_17759_KO_Lin9_SRP221087	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.1151
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AZD1480_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147535
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.325
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20483
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893871
TGFBR3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13172
CTCF	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867618
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89724519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00232
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21256
Ovary	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.04273
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20354
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051297
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JW-1726-SM-3GADN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988908
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857296
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52154207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31781
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1529
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09392
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.87858
BRD-K91885806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05686
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.066
GSE190761_0_v_1_samd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05367
BRD-K53326976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75038
TRIP12	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86143816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05494
Perturb_8947_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.68946
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32148
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4430	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41524
Perturb_14680_KO_P2Y14_SRP044222	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.26578
BRD-A68797623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59015
MAZ	ENCODE Transcription Factor Targets	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_86_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04609
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897975
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861394
Caki-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
PCI6A	DepMap CRISPR Gene Dependency	1.0	3.45735
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO201	CCLE Cell Line Gene Expression Profiles	1.0	1.6502
15-delta prostaglandin J2-1011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92364
BRD-K26051610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15504
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843254
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.34489
TAF2	Pathway Commons Protein-Protein Interactions	1.0	null
SCYL2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13689
OCIMY5	DepMap CRISPR Gene Dependency	1.0	3.25191
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.94054
KYSE-70	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.98334
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRCAM	Pathway Commons Protein-Protein Interactions	1.0	null
Cellular responses to stimuli	Reactome Pathways 2024	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63061
DMAP1	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57186295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67963
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63532
Substance Abuse Problem	DisGeNET Gene-Disease Associations	1.0	null
Perturb_8009_KD|OE_PSAT1|TP53_SRP406950	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUDT21	Pathway Commons Protein-Protein Interactions	1.0	null
HLX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00444474
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BRD-K97748753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36487
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.895047
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SDC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00502162
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17459
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GNB3	Pathway Commons Protein-Protein Interactions	1.0	null
Fer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ERCC1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46915
J7 hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-378c	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53173
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16727_KO_Mbd2_SRP326773	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.6388
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130956_0_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESRRG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559468
THOC2	Pathway Commons Protein-Protein Interactions	1.0	null
SNX2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29086754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79037
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43547
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975681
Cellular response to heat stress	Reactome Pathways 2024	1.0	null
COPD - Chronic obstructive pulmonary disease_Bronchial epithelium_GSE3320	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.31131
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70905
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41691
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07998
Lung adenocarcinoma_LUAD_TCGA-78-7633-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31311
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16754
NDUFA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439496
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.48566
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89114
VPS33B	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76412
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PIP4K2B	Pathway Commons Protein-Protein Interactions	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848791
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
EPPK1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087741
GSE132369,GSE132371_4_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365888
Perturb_4146_KO_Bcl11a_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.301
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74231
POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040605
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07082
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23646
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38798
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867716
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07674
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.863244
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1444
BRD-K56572622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33786
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K85440939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34672
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50842
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0927
BRD-K55446881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04735
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11995
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97359891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04204
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00683
FAM89B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00774895
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895043
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_36_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07853
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GAPDH	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8554
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052487
OAW42	DepMap CRISPR Gene Dependency	1.0	3.71012
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A05422420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52893
17414055-Table3	GeneSigDB Published Gene Signatures	1.0	null
ECC10	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.97051
BRD-K27953820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36638
Perturb_6256_KO_CIC_ERP108370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SERPINA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00407783
hsa-miR-199a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
SEC24D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60005
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31781
TAL1	ENCODE Transcription Factor Targets	1.0	null
CHRNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593234
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Rucaparib_1µM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141054
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48983
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997699
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Interrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73123
MED16	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8622-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
NCAPD2	Pathway Commons Protein-Protein Interactions	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03379
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UPF2	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Fasudil_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131041
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7A-Table_S7A_Hippocampal_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Rhabdomyosarcoma	CTD Gene-Disease Associations	1.0	1.10769
COLO-320-HSR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TOX4	Pathway Commons Protein-Protein Interactions	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE196699_7_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR16	DepMap CRISPR Gene Dependency	1.0	3.43453
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052554
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986404
Hallucinogen dependence	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.012
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LUC7L2	Pathway Commons Protein-Protein Interactions	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.902592
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20565
JNK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
SHROOM3	Pathway Commons Protein-Protein Interactions	1.0	null
BTAF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K58324650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26788
trichostatin A-4770	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRP68	Pathway Commons Protein-Protein Interactions	1.0	null
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21911
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878368
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2R1B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19556
PSTPIP2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4421	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Drug Habituation	DisGeNET Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2578-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-7557-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180951_2_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.44297
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03094
BRD-K47883435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24379
GTEx Uterus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.04046
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
RAD50	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29865
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.35041
CUL1	Pathway Commons Protein-Protein Interactions	1.0	null
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61925
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932258
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K92011556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87989
pimosertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13592
Leber congenital amaurosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580417
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF317	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13567
PMC8851354-Table_5.xlsx-FUS-DDIT3_reg_FD-bound-Supplementary_Table_5_Genes_regulated_by_FUS-DDIT3_that_are_FUS-DDIT3_targets_in_MLS_402-91_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43036
CF-61-EH59_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238087
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PLA2G12A	Pathway Commons Protein-Protein Interactions	1.0	null
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89166
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_1_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4353
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.861178
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990197
hsa-miR-23c	TargetScan Predicted Conserved microRNA Targets	1.0	0.002088
MYC	ENCODE Transcription Factor Targets	1.0	null
NOS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.60406
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229522
EM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53246
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970384
UOK101	CCLE Cell Line Gene CNV Profiles	1.0	1.40638
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF5L	Pathway Commons Protein-Protein Interactions	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2486
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00372812
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23904
ARF5	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37013
EIF2D	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K96637144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46976
BRD-K31757099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18259
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF3C3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.131781
Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11782650-41598_2025_88526_MOESM1_ESM.pdf-25-ZNF573_ZNF573	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70674
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28761
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7789
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918929
POGZ	Pathway Commons Protein-Protein Interactions	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0629
RPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26426
FHOD1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3065-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.985257
BRD-K86797399_pracinostat_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPATA5L1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539717
BRD-K21367867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00234
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ATM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199255,GSE199356_0_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC31B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ischemic Stroke	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-644	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47962810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97832
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23364
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73338
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45584
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.67931
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZRANB2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.947729
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PAK4	Pathway Commons Protein-Protein Interactions	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14656
Perturb_17364_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.59018
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4726-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
XRN2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.91217
Weight Gain	CTD Gene-Disease Associations	1.0	1.25838
RACGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.877658
DDX42	Pathway Commons Protein-Protein Interactions	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877428
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48671
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.39892
BRD-K63856509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17548
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19928
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98698
CHD3	Pathway Commons Protein-Protein Interactions	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30895
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48891
BRD-K35964249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6534
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39429
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A815-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.924419
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068988
KLF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484838
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.80124
scopolamine-4803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K40939137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1152
Perturb_1686_OE_Mnx1_SRP373412	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895885
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.069421
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.39507
BRD-K41063113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54333
TUBA4A	Pathway Commons Protein-Protein Interactions	1.0	null
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45682
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0502
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2818
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928001
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068112
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A47Z-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27759
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97256018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42098
GSE181749_2_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3474
SPTBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00725928
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BLM	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4660	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
HELLS	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chr10_116687864_C_T_b38	GTEx eQTL 2025	1.0	4.15746
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.8083
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K80225716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13948
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28618
LRRC8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0102335
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDKN2AIP	Pathway Commons Protein-Protein Interactions	1.0	null
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270658
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRMT1L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97153
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K01182779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38147
hsa-miR-1825	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
BRD-K95935249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98507
BRD-K14868348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34931
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.222479
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A18579359_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD8	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12041165-401_2025_2886_MOESM1_ESM.xlsx-Meta_CAA_vs_AD-Genes_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
nicergoline-6251	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052553
BRD-K83475223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60111
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_5_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13599
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7985
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
DTYMK	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09959
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14355
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833471
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16509
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93435
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43797
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45729
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.03065
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1395
ht55	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
valproic acid-6934	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11364504-41388_2024_3115_MOESM2_ESM.pdf-178-HMGA1_HMGA1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06924
A549_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.020745
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
BRD-A37105798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06825
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42395
hsa-miR-922	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938947
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00448
DIAPH3	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ivabradine (hydrochloride)_HepG2/C3A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.011804
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bone mineral density (hip)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08205503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86591
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.31514
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28955
B2M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00493373
BRD-K16686330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07584
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hel	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20588
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87714
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.871922
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMARCD1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
raubasine-5459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4418	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949612
BRD-K02959126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33213
BRD-K77403813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21107
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56737
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02071
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
External ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
ficolin-1-rich granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-A_FUS-DDIT3_vs_both_controls-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.861178
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	1.11306
Adrenocortical carcinoma_ACC_TCGA-OR-A5JW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPG	Pathway Commons Protein-Protein Interactions	1.0	null
Organic Mental Disorders, Substance-Induced	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87642
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCA2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNUPN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.830903
neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.275569
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832084
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5709
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89313
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38948
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7617
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K86600397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69766
PMC6606599-41598_2019_45777_MOESM14_ESM.xlsx-SAVA_DE_genes_promoter_DMRs-Unnamed_22_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3998
RGS16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00718217
BRD-K16862492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0743
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2245
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Gill	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
hsa-miR-4273	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
METTL13	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45706
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50426
moxisylyte-7015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cervix, uterine	HPA Tissue Protein Expression Profiles	1.0	0.861178
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SHSY5Y	CCLE Cell Line Gene Expression Profiles	1.0	1.43372
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KIF4A	Pathway Commons Protein-Protein Interactions	1.0	null
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24486
HDAC1	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16786
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.09576
S0-EE-Y6Y9_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262574
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RTP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00729997
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14007
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bicuculline-4574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A20182314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53881
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06299
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060764
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.21714
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110580_1_v_0_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAVCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00741387
Lung squamous cell carcinoma_LUSC_TCGA-33-A4WN-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225519
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60667
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843174
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00485
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36729
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849874
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR5	Pathway Commons Protein-Protein Interactions	1.0	null
EDC4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040586
UBN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBE2N	Pathway Commons Protein-Protein Interactions	1.0	null
ODF3L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00843249
anthraquinone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56916
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZZ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00797
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6257
pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.638229
HTT	ChEA Transcription Factor Targets	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8631
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.27445
RBM10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11837_KO_Slc45a3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.51531
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00522
kidney	HPA Tissue Gene Expression Profiles	1.0	0.828322
hsa-miR-1204	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31179
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17629
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23147
RERF-GC-1B	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
DOCK5	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-503	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K94518115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29647
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6115_OE_Cebpb_SRP132418	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.75045
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874639
hsa-miR-345	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3002
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.4089
BRD-K91341416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35104
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.12254
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6159
TMEM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7054
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06418
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.22177
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12213
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.83707
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876825
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2474
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515531
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2747
DRG1	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGEF1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2433
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
drofenine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66198
LMNA	Pathway Commons Protein-Protein Interactions	1.0	null
Left atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.007
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.10272
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3545-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34465
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41896
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41168
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A56427952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47057
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
TUBGCP4	Pathway Commons Protein-Protein Interactions	1.0	null
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Stomach Neoplasms	CTD Gene-Disease Associations	1.0	1.09541
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K86797399_pracinostat_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955328
posteroventral (inferior) parietal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847995
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
levetiracetam_rattus norvegicus_gpl1355_hippocampus_gds1864	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961829
KARPAS-422	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53244
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.2895
BRD-K01225247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31466
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72621
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24225
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059192
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12429
ZNF143	ENCODE Transcription Factor Targets	1.0	null
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.975
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63W-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.976023
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.729044
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956002
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19135
BRD-K09895564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09538
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.13114
BRD-K00551139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0654
TRIM21	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879541
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K73840377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61749
Liver Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.967535
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.953395
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31788
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8492
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78347804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58926
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24058
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216914
YTHDC2	Pathway Commons Protein-Protein Interactions	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10747
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35859
BRD-K79067166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10349
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.638229
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860559
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
FERMT1	Pathway Commons Protein-Protein Interactions	1.0	null
ERAL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200352_9_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
ANAPC7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K23556321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1991
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LYZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00431342
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14852
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM126B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44305
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCLC21H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33479
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A39660642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59967
USP10	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_486_KD_ELAVL1_SRP339781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Interrenal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261
hsa-miR-378	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
ANLN	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5221
KANK1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_17362_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.92411
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16762
GULP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88070373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62006
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47391428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26085
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865181
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85127
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nonalcoholic Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5ST-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06863452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24518
ERCC6L	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996683
NCIH1341	CCLE Cell Line Gene Expression Profiles	1.0	1.47127
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94097
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836351
PAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652812
PRPF3	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047088
LEFTY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054015
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61886
BRD-K10483446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51304
PTBP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
S0-EE-WH3B_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270877
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02404
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6128
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958383
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEx Lung 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	5.36546
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36158
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054399
CHLA57	DepMap CRISPR Gene Dependency	1.0	5.48061
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.41531
Perturb_2817_KD_SASH1_SRP231434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
hsa-miR-4506	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.899287
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59039
nerve	GTEx Tissue Gene Expression Profiles	1.0	2.13663
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.51928
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP2K7	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0623
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11843
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHC class I protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.698
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29098
Lung adenocarcinoma_LUAD_TCGA-55-7726-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_ATF3_SMC_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15579
hsa-miR-3690	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054816
BRD-K58491882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18788
VRK1	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBMX	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211357_2_v_0_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF2S3	Pathway Commons Protein-Protein Interactions	1.0	null
BRIX1	Pathway Commons Protein-Protein Interactions	1.0	null
large intestine cancer	GWASdb SNP-Disease Associations	1.0	0.499367
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K29702569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09702
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00482
BRD-K46742113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24903
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03395
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16637_KO_Drd2m_SRP377988	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.68315
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD8	Pathway Commons Protein-Protein Interactions	1.0	null
GSU	DepMap CRISPR Gene Dependency	1.0	2.01939
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5786-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vertical cup-disc ratio (adjusted for vertical disc diameter)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35472
IPC298_SKIN	CCLE Cell Line Proteomics	1.0	3.60063
DD-74-PJ26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249231
Rectum adenocarcinoma_READ_TCGA-AG-3742-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZR-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85527716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11203
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20487
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.313189
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054827
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12283
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8674
RBM39	Pathway Commons Protein-Protein Interactions	1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05907
Cannabis dependence	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.012
NBN	Pathway Commons Protein-Protein Interactions	1.0	null
GEMIN6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904145
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35493
MATR3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ROCK2	Pathway Commons Protein-Protein Interactions	1.0	null
TPX2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22099
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11772
DCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00759344
BRD-K12181036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03039
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83593
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.33434
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.39507
PLRG1	Pathway Commons Protein-Protein Interactions	1.0	null
GC-74-QF56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34951
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335724
neurofilament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.275569
MELHO	DepMap CRISPR Gene Dependency	1.0	2.37458
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K43023353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42732
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07522
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS1_2019_Affy_IDs_RA-STvsOA-ST-Unnamed_2_PAX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91235484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10202
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
Freckles	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.01549
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874639
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34475
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15825
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878963
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225869_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chicago Sky Blue 6B-6626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39567
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.069138
hsa-miR-378b	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269174
Melanoma	CTD Gene-Disease Associations	1.0	1.16104
GID8	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN010_HEPG2_24H:H11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36334
BRD-K93747373_HG-5-113-01_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06824
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14117
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881097
orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.630027
hsa-miR-3926	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.325
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25291
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pepstatin-4790	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCC-ER	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.97002
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77291
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08371
PMC3435504-msb201237-s2.xls-Supp_Table_4a-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05351
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891539
ONS76	DepMap CRISPR Gene Dependency	1.0	3.24835
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.27409
BRD-K11696817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64445
CRCGN015_HEPG2_48H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65843
EOMES	ChEA Transcription Factor Targets	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRA_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02305
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.0273
ACHN	GDSC Cell Line Gene Expression Profiles	1.0	1.8121
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.06442
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27955
Thalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.066
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40923781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0046
DUS4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2192
POLR3D	Pathway Commons Protein-Protein Interactions	1.0	null
chr10_116727650_T_C_b38	GTEx eQTL 2025	1.0	2.21857
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PYHIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600547
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36320220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25195
BRD-K28919392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83635
gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.061834
hsa-miR-3665	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044184
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.7857
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
NELFB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBL1XR1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17790291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20028
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.917428
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
Learning Disorders	CTD Gene-Disease Associations	1.0	1.64303
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46446
BRD-K77908580_entinostat_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.696306
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.421503
KIF19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612026
DiFi	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.97972
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7908_KD_SNRNP200_SRP364705	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.319
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135030_11_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57826
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16566
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01234
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873101
pioglitazone-5972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898751
Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-214	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
PMC8283158-mmc2.xlsx-TCF4_Glut-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09568
MLKL	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7964-01A-21R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3173
cellular_component	GO Cellular Component Annotations 2015	1.0	null
occipital	GeneRIF Biological Term Annotations	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-23a	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0904
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.75945
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12333
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07853
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15943105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18855
decreased susceptibility to diet-induced hepatic steatosis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6248
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HK2	CCLE Cell Line Gene Expression Profiles	1.0	1.35797
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51348
BRD-K67533212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50816
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.65627
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MRTO4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061634
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36716
Hsf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOXL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00391008
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32246
NB13	DepMap CRISPR Gene Dependency	1.0	2.72518
DMRT1	ChEA Transcription Factor Targets	1.0	null
Perturb_14667_KO_Sirt3_SRP277814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.6824
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45097650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47594
NF1	Pathway Commons Protein-Protein Interactions	1.0	null
MORF4L1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFC5	Pathway Commons Protein-Protein Interactions	1.0	null
EPS8L2	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Filgotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142508
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.861178
PMC12804683-41531_2025_1230_MOESM1_ESM.pdf-117-GTF2I_GTF2I	Rummagene Transcription Factor Associations 2026	1.0	null
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12841
BRD-K20846358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72992
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDX1_KO_GDS4348_360_mouse_Proximal small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75679
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PARP1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4660	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28155
KDM5A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_1day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.91724
Longissimus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.257
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53518
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHEK1	Pathway Commons Protein-Protein Interactions	1.0	null
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5268
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046118
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13764
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954159
EWSR1	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	4.16584
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDLIM7	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1205	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
BRD-K89366259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85729
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2089
BRD-K28785305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07553
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.13415
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	2.78795
SQSTM1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_3007_KD_Satb1_SRP068358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.79621
regions	GeneRIF Biological Term Annotations	1.0	null
GSE208634_1_v_2_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_5712_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.1069
TLN2	Pathway Commons Protein-Protein Interactions	1.0	null
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2098
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908555
TUBG1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K06146578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70527
SHC1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_13039_KD_Tardbp_SRP314028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.42654
BRD-K91696235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41634
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34947
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16652
PMC10244377-41467_2023_38797_MOESM7_ESM.xlsx-4d_BioGRID_RBP-BIOGRID_CDC5L_CDC5L	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01787
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32999
NR2F6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964796
HSPA5	Pathway Commons Protein-Protein Interactions	1.0	null
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	2.1842
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88216
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855985
PRPF6	Pathway Commons Protein-Protein Interactions	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19495
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS2_2019_Affy_IDs_SignalsQN-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09747
UBL4A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96572
PIP4K2C	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8945_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.40883
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85336
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04076
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6089
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881641
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11977
BRD-K09414286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53837
BRD-K93442068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6145
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.97234
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRPA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
BRD-K89660028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09727
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM4SF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505044
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.697921
KYAE1	DepMap CRISPR Gene Dependency	1.0	3.99424
Sarcoma_SARC_TCGA-QQ-A8VG-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65954
Melanosis	DisGeNET Gene-Disease Associations	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HSPA6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42636
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23724
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68556
Perturb_16088_KD_Pml_SRP306364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.59807
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00732971
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43173
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49674
hsa-miR-3156-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BL8868 (PRKCD)	NURSA Protein Complexes	1.0	null
SEH1L	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_609_KO_Myb_SRP062948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.95459
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPEN	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.4768
Acute Myeloid Leukemia_LAML_TCGA-AB-2901-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small_Intestine-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.17249
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5343
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HIP1R	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-370	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15235
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37079
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EWSR1	ChEA Transcription Factor Targets	1.0	null
decreased susceptibility to weight gain	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EPHB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00375036
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.12525
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91225
ENSG00000286190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34621
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02028
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
YWHAG	Pathway Commons Protein-Protein Interactions	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26371
GTF3C2	Pathway Commons Protein-Protein Interactions	1.0	null
Chromosome Aberrations	CTD Gene-Disease Associations	1.0	1.12391
SMC2	Pathway Commons Protein-Protein Interactions	1.0	null
SZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902372
Spinal Cord Diseases	CTD Gene-Disease Associations	1.0	1.04051
GSPT1	Pathway Commons Protein-Protein Interactions	1.0	null
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05082
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5471
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328994
BRD-K00046588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13575
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28069
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12815
PMC3369932-pgen.1002751.s026.pdf-47-RFX7_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38438
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.63049
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	1.74248
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.49864
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926799
SEC23A	Pathway Commons Protein-Protein Interactions	1.0	null
EXOSC6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CROT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553273
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-23b	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
BRD-K16937802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5447
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40704
POLR2A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6606
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98715
GSE173810_4_v_6_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051826
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.983354
sulindac-5103	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
cSARS Bat SRBD_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.78533
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-37-JM16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243607
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25182
MELK	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835725
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31014
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CSNK2A1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69848
CTCFL	ENCODE Transcription Factor Targets	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864918
LRRC1	Pathway Commons Protein-Protein Interactions	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31803
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHERP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77535
BRD-K90111788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15475
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32577562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17267
MAP2K3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K45916030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18532
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08293
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23016
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_13484_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.247
UBQLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40729
NFIC	Pathway Commons Protein-Protein Interactions	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08993
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
3'-fluorobenzylspiperone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42078
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28065
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1091
BRD-A64091909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33881
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86086
AURKB	Pathway Commons Protein-Protein Interactions	1.0	null
aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.704355
abnormality of the intestine	GWASdb SNP-Phenotype Associations	1.0	0.248394
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NSUN5	Pathway Commons Protein-Protein Interactions	1.0	null
PUF60	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K79376287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73575
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8554
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
CDC16	Pathway Commons Protein-Protein Interactions	1.0	null
Ovotestis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8979
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.9729
Body Mass Index	dbGAP Gene-Trait Associations	1.0	0.081977
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC7A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00357445
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7831-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UCHL5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01179
NCIH2291	DepMap CRISPR Gene Dependency	1.0	3.25125
BRD-K59772014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07238
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903904
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2867_Mut_FBXW7_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077519
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378372
PSMA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00715391
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	3.2345
TPR	Pathway Commons Protein-Protein Interactions	1.0	null
RBFA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842798
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26321439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23803
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.529675
U178	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41183
CWC22	Pathway Commons Protein-Protein Interactions	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51382
BECKER	DepMap CRISPR Gene Dependency	1.0	3.10341
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21514
NCOR2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K73780763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37936
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07938
SLC18A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555244
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUFU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580799
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81702
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08377
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDRGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477446
FOSL1-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-S7_Data_List_of_all_genes_that_were_upregulated_in_HEK293DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.66663
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77537
ACIN1	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-378i	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Perturb_15358_KO_Tfap4_SRP212619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.49
Perturb_12905_KD_MDC1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.82299
CREB1	ENCODE Transcription Factor Targets	1.0	null
DCTN1	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41106
DDX17	Pathway Commons Protein-Protein Interactions	1.0	null
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.69597
Perturb_16111_KO_Dnm2_SRP139918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.573
cSARS Bat SRBD_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.87627
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21904
DSP	Pathway Commons Protein-Protein Interactions	1.0	null
MEI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582189
UBE2M	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE129772_2_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01698
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58498,GSE58501_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF12	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13242
NCIH520	DepMap CRISPR Gene Dependency	1.0	2.78614
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
EEFSEC	Pathway Commons Protein-Protein Interactions	1.0	null
TNKS1BP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38061
bufexamac-5515	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42995703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70138
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF3B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11459
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40901
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.375859
Ocular hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
RBM14	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857772
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-508-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-A07195938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.71013
ILF3_02_94	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59704
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01363
CORL88_LUNG	CCLE Cell Line Proteomics	1.0	2.02057
PRPF8	Pathway Commons Protein-Protein Interactions	1.0	null
SNAPC4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889691
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39698
CPSF3	Pathway Commons Protein-Protein Interactions	1.0	null
SUPV3L1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4529-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859926
RBM17	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBA5	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16287
AQR	Pathway Commons Protein-Protein Interactions	1.0	null
droperidol-5690	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
RAE1	Pathway Commons Protein-Protein Interactions	1.0	null
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDC73	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1226	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K43911180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46346
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ORC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677427
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
PSMC5	Pathway Commons Protein-Protein Interactions	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961855
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP24	Pathway Commons Protein-Protein Interactions	1.0	null
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4436b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.895158
hsa-miR-378d	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3856
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.605341
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52357
RFC2	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.874455
BRD-K68305833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27505
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24908
ARAP1	Pathway Commons Protein-Protein Interactions	1.0	null
RBM4	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18137
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K27092365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03249
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_2628_OE_HPGD_SRP292282	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.08752
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
U2SURP	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09442
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14398
A549_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136175
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Choline	CTD Gene-Chemical Interactions	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.52929
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05231
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35171
HD-26-KX74_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306094
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX23	Pathway Commons Protein-Protein Interactions	1.0	null
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZM-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868668
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MLH1	Pathway Commons Protein-Protein Interactions	1.0	null
CPNE3	Pathway Commons Protein-Protein Interactions	1.0	null
neurological	GAD High Level Gene-Disease Associations	1.0	0.293278
hsa-miR-339-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24284
BRD-K45177540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41185
UE-90-AA63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233061
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8874
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.87656
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LAS1L	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897975
KIF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21673
aging	GAD High Level Gene-Disease Associations	1.0	0.293278
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FUBP1	Pathway Commons Protein-Protein Interactions	1.0	null
SPINK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539342
Kidney Tubular Necrosis, Acute	CTD Gene-Disease Associations	1.0	1.03122
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1211
NAT10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29288
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857984
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22372
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86797399_pracinostat_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_7054_KO_Tead1_SRP229838	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.1871
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846663
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.741003
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885881
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1436	CCLE Cell Line Gene CNV Profiles	1.0	1.4301
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15861
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDK1	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66271
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10923
FIP1L1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K73176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09172
ADNP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBNA1BP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.912829
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313377
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13291
Barrett Esophagus_Esophageal Tissue_GSE1420	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.06179
BRD-K49866832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04226
PSMD11	Pathway Commons Protein-Protein Interactions	1.0	null
KANSL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NELFCD	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78692225_-666_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.969137
BRD-K36689392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00583
BRD-K75067815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30544
Perturb_9187_OE_NeuroD4_SRP390425	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19803
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GPATCH8	Pathway Commons Protein-Protein Interactions	1.0	null
TMOD3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70478
GSE70499_4_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15784
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48342
PSMD12	Pathway Commons Protein-Protein Interactions	1.0	null
motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.387794
BRD-K26765362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66117
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14422
NPM1	Pathway Commons Protein-Protein Interactions	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ARFGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.37252
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046329
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47695
COPS5	Pathway Commons Protein-Protein Interactions	1.0	null
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05972
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92795658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94271
ABCF3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46074482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00519
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917692
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab8_TRIM11-KD-up_genes-Table_8_Up-regulated_genes_in_TRIM11-KD_TRIM11-KD1_Control_overlap_TRIM11-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.24087
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GEMIN4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13781
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRPF19	Pathway Commons Protein-Protein Interactions	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549324
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69194
ACSS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571992
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71578
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26812
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
15-delta prostaglandin J2-4455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
PKN2	Pathway Commons Protein-Protein Interactions	1.0	null
OSC19	DepMap CRISPR Gene Dependency	1.0	2.58499
STAG2	Pathway Commons Protein-Protein Interactions	1.0	null
API5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27316
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OCI-M1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUPT16H	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837843
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414293
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68069
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47619
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.91138
GSE149359_3_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02725
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IPC-298	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.99594
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56032186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34705
fluoxetine_mus musculus_gpl1261 _gds2803	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51454545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05137
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11316
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19715
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.74545
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.57186
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61199
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08461
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34964
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96627018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00849
EEF1A1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03111
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XM-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16769
KYO1	DepMap CRISPR Gene Dependency	1.0	2.67883
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80751
GTF3C1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51018
DYNLL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98832
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31362
BRD-K87617154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02575
NCI-H1355	COSMIC Cell Line Gene Mutation Profiles	1.0	null
neoplasm of the large intestine	GWASdb SNP-Phenotype Associations	1.0	1.05066
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6001
amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.440162
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38379
BRD-A16827030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20966
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.1671
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.908492
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_6527_KO_Trp53/Nf1/Pten/Pot1a/Pot1b_SRP293265	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06117
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35282
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216147_2_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057989
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895885
pralidoxim	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13973
COLO-205	GDSC Cell Line Gene Expression Profiles	1.0	2.82081
hsa-miR-4291	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93646
PLK1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859656
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836081
BRD-K90157100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06419
CPSF1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17459
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.90153
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
RTCB	Pathway Commons Protein-Protein Interactions	1.0	null
TUBGCP3	Pathway Commons Protein-Protein Interactions	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF3L	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
SF1_01_146	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.03265
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRPB	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.915
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13736
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_AC480_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189446
BRD-K05304510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6336
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Heat shock 70kDa protein 12A	InterPro Predicted Protein Domain Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6776-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38966099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28179
SNRPD1	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased susceptibility to ischemic brain injury	MGI Mouse Phenotype Associations 2023	1.0	null
Anemia	CTD Gene-Disease Associations	1.0	1.18059
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K49383373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00098
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
SMARCAD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CATSPER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00543747
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD7	Pathway Commons Protein-Protein Interactions	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1436
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23764
CTTN	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86240647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10597
SPIRE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00680979
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56741
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49824
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_9564_KO_Nfkb2_SRP256294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.36125
ZNF638	Pathway Commons Protein-Protein Interactions	1.0	null
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96289
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56122
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-A03182941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04172
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.934514
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00935
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.08963
PCDH17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700183
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854037
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870184
PROC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542173
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56470219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24362
all	GWASdb SNP-Phenotype Associations	1.0	0.033178
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23159
BRD-K37720887_SB-525334_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CWC15	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882868
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JX-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9178
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.93072
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
KPNA2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_1086_KD_MET_SRP295211	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
YBX3	Pathway Commons Protein-Protein Interactions	1.0	null
EIF3I	Pathway Commons Protein-Protein Interactions	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07343
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	1.4322
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07604
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.990578
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60064
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120413,GSE120447_3_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34141
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2666_KD_JUN_SRP357624	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.37907
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15496
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851329
PARVB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K52194153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06651
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06344
SUMO1	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.26638
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TUBGCP2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF91_01_123	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59443
CASP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00433261
BRD-K99827210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29854
Chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3746
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2665-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14375790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95778
BRD-K14961381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19244
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.17127
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SYMPK	Pathway Commons Protein-Protein Interactions	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37084
USP39	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148692,GSE148695_7_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00742
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC19A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615474
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072078
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894145
EIF2AK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502155
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRRM1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HeLa	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.13611
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC47	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48856
NCAPH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136397_1_v_0_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMN2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18373
BRD-K37588779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59087
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09814
hsa-miR-4501	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
18435859-ShorterGeneList	GeneSigDB Published Gene Signatures	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.07947
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL1_GRHL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KIF2C	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21935
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05865
AP3S1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYK_druginhibition_154_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.74601
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.55095
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16748
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20667
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AML193	DepMap CRISPR Gene Dependency	1.0	2.60029
C1orf35	Pathway Commons Protein-Protein Interactions	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.8866
NCIH929_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	5.80905
TIAL1	Pathway Commons Protein-Protein Interactions	1.0	null
TMIGD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637036
GMPS	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.125677
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
NCI-H847	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.17535
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INTS6	Pathway Commons Protein-Protein Interactions	1.0	null
FEN1	Pathway Commons Protein-Protein Interactions	1.0	null
RFX1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRTCAP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00691322
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48055
BRD-K32782599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25299
ACAD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669711
BRD-K06529600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68581
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.07234
BRD-K86911380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30311
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
clozapine-6947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SE5C-1326-SM-4BRUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908164
rara_21911359_f9_teratocarcinoma_lof_mouse_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	2.73105
Systolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
Acute Myeloid Leukemia_LAML_TCGA-AB-2853-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7241
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.033251
hsa-miR-224	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03124
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5714_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.42316
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15371
PAXIP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K96218803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01418
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58244
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21148
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59552
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01608
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887673
chaperonin-containing T-complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.266
SRSF5	Pathway Commons Protein-Protein Interactions	1.0	null
BCL2L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00402853
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70625
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40515
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93986
BRD-K13938991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61246
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55649
hsa-miR-494	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
SUSA	DepMap CRISPR Gene Dependency	1.0	4.90132
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13909
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.902547
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284393
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6261
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29959
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1024
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0207
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.937079
decreased susceptibility to induced morbidity/mortality	MGI Mouse Phenotype Associations 2023	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21188
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1123
CWC27	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_16949_OE_GATA6/ZBED2_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.43507
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30828
SEC24C	Pathway Commons Protein-Protein Interactions	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.846158
SF3B3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BZW2	Pathway Commons Protein-Protein Interactions	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054955
Oligospermia	CTD Gene-Disease Associations	1.0	1.17067
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
valproic acid-497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32251
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25644
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946067
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.063569
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.7286
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Nephritis	CTD Gene-Disease Associations	1.0	1.25463
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87266
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04272258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08371
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
TNFAIP2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYCN_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5019
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17889110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4794
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
chr10_116702472_C_T_b38	GTEx eQTL 2025	1.0	1.67039
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_29_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933784
BRD-K77890526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34482
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899013
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.916011
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32108
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35055
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911021
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893716
GTF3C5	Pathway Commons Protein-Protein Interactions	1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6094
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K42361742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.83566
PMC8851354-Table_2.xlsx-Genes_reg_by_FUS-DDIT3-Supplementary_Table_2_Genes_significantly_regulated_by_FUS-DDIT3_expression_in_HT1080_cells_adjusted_p-value_0_05_and_log2_Fold_change_1_or_-1_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98922
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10719
inner CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858427
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.061154
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP7	Pathway Commons Protein-Protein Interactions	1.0	null
SUIT-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.14165
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856611
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.019
BRD-K87167435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18892
CPSF7	Pathway Commons Protein-Protein Interactions	1.0	null
INTS3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.924744
Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.71542
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08423
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06746
TRAF3IP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00751002
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-2115	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Perturb_15357_KO_Tfap4_SRP212619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.80031
BRD-K18296708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08539
SP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19709
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.98022
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NFKB2	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00137
BRD-K05228434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06046
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81427
GCAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00581299
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5417601-pone.0176879.s001.xlsx-Ctrl_vs_UCHL1_KD_result_DEseq_f-id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13226207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35827
PIGH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676375
hsa-miR-4695-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6339
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_SALL4_19060217	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	0.833261
GSE190384,GSE190386_2_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DYNC1LI1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15958
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75044
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL24	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
U2-type catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
BRD-K89584810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00561
GSE87412,GSE92423_3_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31091
PDGFRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00903574
MCAS	CCLE Cell Line Gene CNV Profiles	1.0	1.63292
FAM129B	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PATU8902	DepMap CRISPR Gene Dependency	1.0	3.36367
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
RPL36	Pathway Commons Protein-Protein Interactions	1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K37253987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23527
SNX12	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20649
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.41829
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33098168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14391
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Idiosyncratic drug effect_Hepatic Tissue_GSE2825	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.20562
BRD-K88707941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26637
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971909
DDX3X	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-631	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
A-61603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08167
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30409
CARD10	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_2869_Mut_IDH1_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.79496
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76126
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32982
GSE79291_1_v_0_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57173429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00423
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173997_1_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8563
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12824706-BLOOD_BLD-2025-028441-mmc3.xlsx-Fig4B_genes_inc_expr_NRF1-gene_name_NRF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-586	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28646
CSE1L	Pathway Commons Protein-Protein Interactions	1.0	null
TRRAP	Pathway Commons Protein-Protein Interactions	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057104
BRD-K08113936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22128
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837447
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.053566
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36152
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-326-GSC2_GSC2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6941881-mmc4.xlsx-IR_only_down_DEGs-List_of_DEGs_that_are_downregulated_upon_PRMT5_KD_only_in_IR_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SUGT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEC59	DepMap CRISPR Gene Dependency	1.0	2.14794
DEPDC7	Pathway Commons Protein-Protein Interactions	1.0	null
NUP153	Pathway Commons Protein-Protein Interactions	1.0	null
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937638
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040045
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K81804676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01028
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.909946
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11422
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28958
DDX39A	Pathway Commons Protein-Protein Interactions	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3886
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824988
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32355
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27449
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916502
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995466
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64586
BRD-K75041300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23484
HSD3B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554417
PRDM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22882
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94381
RCBTB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573394
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	1.67883
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3584
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05305
ENY2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EXOC7	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907365
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4761-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.078
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.3604
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944604
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35879
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-P53_DN_V1_DN-Ensemble_gene_ID_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PPARG-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850102
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPS3	Pathway Commons Protein-Protein Interactions	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962885
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55086
hsa-miR-3162-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32183
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52117
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8253910__F5	PFOCR Pathway Figure Associations 2024	1.0	null
SRP54	Pathway Commons Protein-Protein Interactions	1.0	null
SNRPE	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A05456882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90474
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAOK1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32266
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29185
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dementia	GWASdb SNP-Disease Associations	1.0	0.332189
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-0.998259
IA-LM	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74245
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4164
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.862737
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937374
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11865
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36655
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.4065
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.97234
CAPZA1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6254_KO_CIC_ERP108370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0982
CDK3	Pathway Commons Protein-Protein Interactions	1.0	null
DLG4	Hub Proteins Protein-Protein Interactions	1.0	null
SMARCC2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_15070_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SMARCE1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22346
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887893
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PFKP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58088
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069668
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC2	Pathway Commons Protein-Protein Interactions	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862112
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931212
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1347
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086267
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	0.529675
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.418
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02838
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2464_KD_SETDB1_SRP344480	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.70219
BRD-A90249268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04376
GSE180525,GSE180528_1_v_3_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83523
Oligodendrocyte_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864918
RXRB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86797399_pracinostat_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29221
intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.14037
KIF21A	Pathway Commons Protein-Protein Interactions	1.0	null
cortical	GeneRIF Biological Term Annotations	1.0	null
CASC5	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Ensembl_ID_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30225
RING1	Pathway Commons Protein-Protein Interactions	1.0	null
ENAH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075202
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9218734-Supplementary_Data3.xlsx-KRIEG-KRIEG_HYPOXIA_NOT_VIA_KDM3A_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-761	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCYL1_knockdown_194_GSE57646	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.15439
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05969
CRCGN015_MCF10A.TP53.M_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1735
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54401
RNASET2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606137
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
THRAP3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-345	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Pons	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1233
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08133
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.80912
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.993357
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938791
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052116
Left middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
PAK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203308_7_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TACSTD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060553
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74915
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00745
PSN1	CCLE Cell Line Gene CNV Profiles	1.0	1.35897
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52215
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947659
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00048155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29694
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958383
Leydig cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
ETV6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13487
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43589
salivary gland	HPA Tissue Protein Expression Profiles	1.0	0.861178
Gill filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
COPG2	Pathway Commons Protein-Protein Interactions	1.0	null
PRKCZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00488758
TRPC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00696169
SLC25A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00442957
RUVBL1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11894_KO_Irgm1_ERP020504	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.04159
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056048
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart failure	GWAS Catalog SNP-Phenotype Associations	1.0	0.042592
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVK18	CCLE Cell Line Gene CNV Profiles	1.0	1.48422
ARCN1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAGED2	Pathway Commons Protein-Protein Interactions	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224298
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10056
GSE101467_0_v_1_dock8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8564
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833848
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3128	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36502
Perturb_5022_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.4815
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
minoxidil-4800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
CAL-12T	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57152
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33124
HMGN3	ENCODE Transcription Factor Targets	1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.832972
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884624
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RANBP2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A652-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06738
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70584304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70246
COLO-668	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64145
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7105
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ML1	CCLE Cell Line Gene Expression Profiles	1.0	1.96568
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.13449
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5751
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.0894
MED12L	Pathway Commons Protein-Protein Interactions	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52829
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11062
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PWP1	Pathway Commons Protein-Protein Interactions	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45301
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
CHD1L	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XF-01A-31R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPC-N	GDSC Cell Line Gene Expression Profiles	1.0	1.558
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1245b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HepAD38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1664
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937087
BRD-K90027990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05311
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1267
POLR1C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K03733288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07908
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2211
J82_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	4.16883
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19933
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980852
GATAD2A	Pathway Commons Protein-Protein Interactions	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
SHOC2	Pathway Commons Protein-Protein Interactions	1.0	null
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1214_KO_Zfp580/Zbtb7a/Klf16_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.92708
E2F6	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6978
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36368
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15104
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938613
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928254
SCML1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12811
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072641
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18477
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CALM1	Hub Proteins Protein-Protein Interactions	1.0	null
TAF9	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88739137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73281
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TANC2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45442
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903844
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38061
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040763
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856533
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01617
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842707
SKMEL24	DepMap CRISPR Gene Dependency	1.0	3.56576
SW1710	GDSC Cell Line Gene Expression Profiles	1.0	1.54556
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875129
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.838287
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	2.16624
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.325
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03222
SPATA5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Systolic Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
SKN3	DepMap CRISPR Gene Dependency	1.0	2.42902
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lysergol-6621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SELENOI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534607
HTT-18923047-STHdh-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
EIF3B	Pathway Commons Protein-Protein Interactions	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.715117
BRD-K96567801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22389
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_91_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-544	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31829
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TARDBP	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A15454510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24394
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RPL19	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EOMES-21245162-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KYM1	DepMap CRISPR Gene Dependency	1.0	6.70527
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	1.58791
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PCNT	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902222
BRD-K48900723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0641
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06482
BRD-K08006576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74924
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57434
MBD3	Pathway Commons Protein-Protein Interactions	1.0	null
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51525
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74172
CA-SKI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37833
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48213
CFPAC1	DepMap CRISPR Gene Dependency	1.0	2.20333
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OGFOD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560911
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
Perturb_3898_KO_TCF7L2_SRP314475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K09100418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09602
Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
TP53-16413492-CHIP-PET-HCT116-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-507-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23151
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	1.88663
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51388
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.861178
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317744
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88028
SRSF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00674357
CENPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12943
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71174
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.09081
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05899
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7748
5149715-890	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-670	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCIH2887	DepMap CRISPR Gene Dependency	1.0	2.3003
BRD-K33961995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0648
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881804
TIGAR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559668
Byssus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
BRD-K33016067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10309
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48228
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6452
EIF2B2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K25718630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05535
GSE130715_2_v_3_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34719
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.560459
Mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72445
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.933861
Renal proximal tubule epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32359
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.31181
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994859
hsa-miR-1245b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K34761198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18482
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.956827
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRNP70	Pathway Commons Protein-Protein Interactions	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
PRMT5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX41	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1568_LUNG	CCLE Cell Line Proteomics	1.0	2.93097
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937638
hsa-miR-423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07227
Catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.325
SFI1	Pathway Commons Protein-Protein Interactions	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523051
WIZ	Pathway Commons Protein-Protein Interactions	1.0	null
OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1648
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.24998
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879602
hsa-miR-338-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.002088
BRD-K53508363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19359
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06589
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042204
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30759
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_68_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
APBB1IP	Pathway Commons Protein-Protein Interactions	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31601
Perturb_9778_KD_Gas41_SRP110498	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.89098
BRD-K03421365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61525
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RNF2	Pathway Commons Protein-Protein Interactions	1.0	null
WAPAL	Pathway Commons Protein-Protein Interactions	1.0	null
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31117
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894145
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935127
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825085
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864723
KLF4	ChEA Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DU-4475	GDSC Cell Line Gene Expression Profiles	1.0	1.85961
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04735
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870103
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC6	Pathway Commons Protein-Protein Interactions	1.0	null
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-3166	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SNU466	CCLE Cell Line Gene Expression Profiles	1.0	2.01549
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52923
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12903_KD_ER_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34687
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.37536
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50151
Substance dependence	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.012
BRD-K56277358_MGCD-265_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986235
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244012
EXOC4	Pathway Commons Protein-Protein Interactions	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03133
BRD-K92291448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1334
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.314278
A549_Carmofur_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00788841
LMO7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAB1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-THRB_THRB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	1.47479
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66821
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.05721
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
SLC13A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581744
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51138
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02086
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.19246
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFIP1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_16610_KO_Phb_SRP229743	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CHD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694652
BRD-K11667893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10037
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6718408-41467_2019_11884_MOESM9_ESM.xlsx-YAP1_RELA_DEGs_mice_human-Human_Gene_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_12904_KD_FOXA1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
vesicle	GO Cellular Component Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.927927
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37097
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23766
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9593_KO_Npp7_SRP148279	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.36278
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
abnormality of the large intestine	GWASdb SNP-Phenotype Associations	1.0	0.319009
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51156
BRD-K21483524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35475
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1016_KO_Nt5e_SRP404924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.14384
A_CA_04_2009_7dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.55596
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13331
hsa-miR-1184	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
Perturb_17359_OE_CREB_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.9281
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052297
SW1710	CCLE Cell Line Gene Expression Profiles	1.0	1.83493
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
NO11	DepMap CRISPR Gene Dependency	1.0	2.6415
hsa-miR-4330	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2707
HTATSF1	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal macrophage morphology	MGI Mouse Phenotype Associations 2023	1.0	null
YEATS4	Pathway Commons Protein-Protein Interactions	1.0	null
TRAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00683675
hsa-miR-378e	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_18_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
TUHR14TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.472
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29258
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46458
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3882_KO_ITPR3_SRP361791	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29901
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03805
PUM2	Pathway Commons Protein-Protein Interactions	1.0	null
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935127
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2737-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03805
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12754
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874639
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
fluoxetine_mus musculus_gpl1261_gds2803	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949683
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CDK9	Pathway Commons Protein-Protein Interactions	1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234351
BRD-K34595193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16783
Perturb_14472_KO_Cbfb/Runx2_SRP233168	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.4215
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95929
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14346
GSE191110_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBA3E	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829566
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73266
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.29133
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Perturb_10707_KO_RbpJ_SRP354352	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71011
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07853
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.027
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01754
hsa-miR-199b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
NCIH716	DepMap CRISPR Gene Dependency	1.0	3.13788
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNPS1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K23280067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62392
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120463_1_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09378
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44935
DDX47	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF426	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31961
E2F6_02_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66297
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62018188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10221
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99005
SUZ12	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	5.46659
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03948
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.1314
15067324-Table3S	GeneSigDB Published Gene Signatures	1.0	null
BAZ1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31277
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_AG-14361_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145824
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09943
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21161559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25964
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30478
AK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526631
SMARCB1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
BRD-K60898929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09965
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.451823
DDX6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216147_0_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CSTF3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5803
AKAP8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21121
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21067
SRF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02608
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19605494-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93775
GF-37-MB64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204188
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-509-3-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43489
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.48591
HLTF	Pathway Commons Protein-Protein Interactions	1.0	null
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.6627
DOK	DepMap CRISPR Gene Dependency	1.0	4.67079
RBBP7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.39045
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K56086519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08334
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Hepatopancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
NCIH526	DepMap CRISPR Gene Dependency	1.0	3.0387
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.894409
PRPF40A	Pathway Commons Protein-Protein Interactions	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.1459
BRD-K69355244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30778
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880587
PPIF_KO_GSE23028_45_mouse_heart (8 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04097
MOSPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00821
Age at smoking initiation in chronic obstructive pulmonary disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
CDC20	Pathway Commons Protein-Protein Interactions	1.0	null
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4505	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMCHD1	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991973
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886282
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
UBE2Q1	Pathway Commons Protein-Protein Interactions	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB7C	Pathway Commons Protein-Protein Interactions	1.0	null
ZEB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0063257
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0326
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08386
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Gene_symbol_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_1_KD_AGO2_ERP014062	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.9859
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64337
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42284
NRG1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07982
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925686
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RPS13	Pathway Commons Protein-Protein Interactions	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.00516
PDGFRL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681044
BRD-K92428153_MYCOPHENOLATE MOFETIL_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55316222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21143
GSE81193_3_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PK-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
CRCGN017_MCF10A.WT.HP_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23372
Infertility, Male	CTD Gene-Disease Associations	1.0	1.05757
SP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09645
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SE-81-RI20_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357059
RBBP5	Pathway Commons Protein-Protein Interactions	1.0	null
pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.173197
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469582
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063843
TRIP10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00405088
EHMT1	Pathway Commons Protein-Protein Interactions	1.0	null
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K41513047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20565
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46345
BZW1	Pathway Commons Protein-Protein Interactions	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MAST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00543651
ANAPC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31825
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57433
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942936
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8005
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8072-01A-31R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54702
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2796
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993708
NDC80	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60944
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT116	CCLE Cell Line Gene CNV Profiles	1.0	1.57493
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	0.861178
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898751
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
trichostatin A-5086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CSNK2B	Pathway Commons Protein-Protein Interactions	1.0	null
KIF27	Pathway Commons Protein-Protein Interactions	1.0	null
P3H1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664511
CRCGN014_HEPG2_3H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09936
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-31-UO16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298129
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.70911
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059646
LIF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00902085
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41015
Cachexia	DisGeNET Gene-Phenotype Associations	1.0	null
RALY	Pathway Commons Protein-Protein Interactions	1.0	null
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60448
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039585
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06824
RAD21	ENCODE Transcription Factor Targets	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
BRD-K28848179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13515
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16007
hsa-miR-4712-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NUP37	Pathway Commons Protein-Protein Interactions	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A60877539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89195
19530251_suppinfo3	GeneSigDB Published Gene Signatures	1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02127
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48319
BRD-K34519525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37784
GSE197342_1_v_0_berberine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058571
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
BRD-K78886448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15746
BRD-K06094529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12096
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5082
TGBC11TKB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.69808
BRD-K81418486_vorinostat_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE130217_0_v_2_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC40	Pathway Commons Protein-Protein Interactions	1.0	null
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
XPO5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A2780_OVARY	CCLE Cell Line Proteomics	1.0	3.05016
SSUH2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67678
DDX39B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K37161540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54109
GCN1L1	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29786
19621087-Table1e	GeneSigDB Published Gene Signatures	1.0	null
BRD-K82968105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26411
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_NFIX-Logfold_change_threshold_1_0_1_NFIX	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16457
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSC4	DepMap CRISPR Gene Dependency	1.0	6.22567
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ORC3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33694
SCOC	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31844
LENG9	Pathway Commons Protein-Protein Interactions	1.0	null
MGAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0110096
HIRA	Pathway Commons Protein-Protein Interactions	1.0	null
increased susceptibility to endotoxin shock	MGI Mouse Phenotype Associations 2023	1.0	null
SLCO1B3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561904
SNRNP200	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF281	ChEA Transcription Factor Targets	1.0	null
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20863
Perturb_2888_KD_Slc25a44_ERP115405	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.20312
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRSF2	Pathway Commons Protein-Protein Interactions	1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.02578
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2E	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6498_KD_DPY30_SRP341550	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.04826
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76057
RPL4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr10_116699496_G_GA_b38	GTEx eQTL 2025	1.0	1.66304
BRD-K31747470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28549
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GSE196699_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K47349225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62628
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.877826
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65184008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3853
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865301
CDC27	Pathway Commons Protein-Protein Interactions	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUIT2	CCLE Cell Line Gene Expression Profiles	1.0	2.86391
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977467
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062708
MCTP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055177
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912166
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90531
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75534737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62316
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAD18	Pathway Commons Protein-Protein Interactions	1.0	null
GSK3A_KD_GDS4305_182_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925209
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
talampicillin-7014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997246
Large_Intestine-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	1.68509
abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.124181
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08455
hsa-miR-543	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYNCRIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060137
BRD-K59922784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03536
meptazinol-4774	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_7545_KO_SCARNA15_SRP277841	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.94105
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	4.64095
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Leukoencephalopathy with vanishing white matter	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
SP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882
SMARCA5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90697692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14398
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66623
IST-SL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Otitis externa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
BRD-K94480039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71782
Perturb_6300_KD_CGA_SRP355115	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Calu-3	GDSC Cell Line Gene Expression Profiles	-1.0	-3.09022
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05108
Perturb_14960_KO_Tfap4_SRP212619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.25578
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
PURA	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
CDR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14335
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00636
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETX	Pathway Commons Protein-Protein Interactions	1.0	null
AP1B1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.79686
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4421_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67956
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27468
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07853
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1748
DNAJA1	Pathway Commons Protein-Protein Interactions	1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE213588_9_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6774-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mbl2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841101
PILRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610357
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
thiamphenicol-7033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
obesity	GWASdb SNP-Disease Associations	1.0	0.704237
FANCI	Pathway Commons Protein-Protein Interactions	1.0	null
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55915
GSE92364_1_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07604
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung Diseases	CTD Gene-Disease Associations	1.0	1.17596
CAL27_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	2.11416
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30593
MACF1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34845
RGS12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00820743
FOS	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FFAR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00445358
KLRC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603402
TFPI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579752
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-04-NG34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220638
NUP93	Pathway Commons Protein-Protein Interactions	1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
MOLP-8	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.43434
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70477
POLD1	Pathway Commons Protein-Protein Interactions	1.0	null
EIF4A3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-422a	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BRD-K67626198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87988
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colchicine-5675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CPSF2	Pathway Commons Protein-Protein Interactions	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05194
GSE206729_5_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
ARGLU1	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA4	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_16950_OE_GATA6_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.49314
GSE169205_0_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7095
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14506
BRD-K92570288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14237
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2097
SREK1	Pathway Commons Protein-Protein Interactions	1.0	null
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06002
BRD-K47692589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10126
BRD-K44622259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06772
KDM4A	ENCODE Transcription Factor Targets	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01698
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19069
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994926
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6606599-41598_2019_45777_MOESM14_ESM.xlsx-SAVA_DE_genes_promoter_DMRs-Unnamed_29_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.877658
ORC2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04709
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06357
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE280	DepMap CRISPR Gene Dependency	1.0	5.59465
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27894
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE67266_5_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UTP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11912
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4056
HIC2	Pathway Commons Protein-Protein Interactions	1.0	null
LRAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572336
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
AC-28-RT00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208903
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58309
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.91952
Memory Disorders	CTD Gene-Disease Associations	1.0	1.56947
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
LC4-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21935
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18604
LRBA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00822441
DPY30	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4310	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915207
SRP19	Pathway Commons Protein-Protein Interactions	1.0	null
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8727
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.91462
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09492
BRD-K42296822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41133
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.029
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0987
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36217
hsa-miR-509-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223908,GSE223909_1_v_6_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856782
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
CADM1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0531
pancuronium bromide-4570	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33107
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13439
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANAPC2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980991
VPS51	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
GTPBP4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04238122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07175
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF3	Pathway Commons Protein-Protein Interactions	1.0	null
OBSCN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522903
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53720386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42013
BRD-K87343552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32196
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K27194553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12123
CRCGN014_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25572
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72374
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45253154_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
15-delta prostaglandin J2-201	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18932
SW620	GDSC Cell Line Gene Expression Profiles	1.0	1.49868
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10978
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35082
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29422
EPB41L1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regionspecific	GeneRIF Biological Term Annotations	1.0	null
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA-96-UO48_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207158
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
outer SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833672
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR26	Pathway Commons Protein-Protein Interactions	1.0	null
HK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
TUBB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64826
BRD-K14364923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31238
BRD-K04695511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70126
PTPRS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593557
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IPO9	Pathway Commons Protein-Protein Interactions	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.28364
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOV21G	CCLE Cell Line Gene CNV Profiles	1.0	1.55045
KIAA1279	Pathway Commons Protein-Protein Interactions	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226064
PMC10330983-ab-22-0432-Supplementary-Table-8.pdf-80-HSF5_HSF5	Rummagene Transcription Factor Associations 2026	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Mantle cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63545
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44908
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.4087
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73385
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72282
MEGF10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE100102_4_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS6KB2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3184	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K10776934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42097
GSE103124_1_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1199
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958383
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTEN_01_301	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.77242
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967569
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72979
EW22	DepMap CRISPR Gene Dependency	1.0	2.7018
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
SCRIB	Pathway Commons Protein-Protein Interactions	1.0	null
HSPB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01564
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36252
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991971
DIAPH1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92703
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35361
Perturb_9500_KI_Trp53_SRP201382	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.87557
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836092
MED4	Pathway Commons Protein-Protein Interactions	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21258
A253	DepMap CRISPR Gene Dependency	1.0	3.33953
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.861178
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78L-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.103
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30214445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47066
brain	HPA Tissue Gene Expression Profiles	1.0	1.47431
15-delta prostaglandin J2-6990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44136
hsa-miR-3605-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SKPNDW	DepMap CRISPR Gene Dependency	1.0	4.89889
BRD-K82968130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66624
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54898824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47294
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30734
Scrapie	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04452
morphological abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.166799
IK	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_17544_KD_MLK4_SRP320486	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.35365
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
haloperidol-492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A06232236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45022
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894145
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07884
Lung squamous cell carcinoma_LUSC_TCGA-46-6025-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT3	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.463
CCNT2	ENCODE Transcription Factor Targets	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38061
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7180-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K28093873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14324
Peroxisomal importomer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.892008
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242899
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5055
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7365-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01754
IPO5	Pathway Commons Protein-Protein Interactions	1.0	null
Substance-Related Disorders	CTD Gene-Disease Associations	1.0	2.88009
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAZ1A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65445351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05443
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08787
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Leukemia	CTD Gene-Disease Associations	1.0	1.20654
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNRNP40	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1338
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.00605
SND1	Pathway Commons Protein-Protein Interactions	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17851
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00929197
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.47286
NFIC	ENCODE Transcription Factor Targets	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06486
NDUFB7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00400993
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12696
CRCGN011_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03645
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED12	Pathway Commons Protein-Protein Interactions	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01922
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95711
H3K14ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09385
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04662
BRD-K86792405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09979
RPS15	Pathway Commons Protein-Protein Interactions	1.0	null
delavirdine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04458
FAF1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05969
ACE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00598085
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22665
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25477
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891912
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5184
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91288
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066858
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2021
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59492
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HIF1A_01_224	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.1581
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.159856
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044857
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hTERT-RPE1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
Perturb_8610_KD_Camta1_SRP048702	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.8938
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842373
CDK12	Pathway Commons Protein-Protein Interactions	1.0	null
OLA1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-378f	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cerebral granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
BUB1B	Pathway Commons Protein-Protein Interactions	1.0	null
VPS36	Pathway Commons Protein-Protein Interactions	1.0	null
INTS8	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP155	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5763-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26005
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80181
BRD-K52391588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44335
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36484
PPARG-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BB-62-MS83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364969
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A98888138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40141
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
PK59	CCLE Cell Line Gene CNV Profiles	1.0	2.56134
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPS19	Pathway Commons Protein-Protein Interactions	1.0	null
RPL7A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29A-06A-12R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02647
HNRNPAB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44173
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04838
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4962
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33242
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20482
dantrolene-3786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_4200_KD_Mecp2_SRP072951	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Thalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.70299
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.12014
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_67_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SF3A3	Pathway Commons Protein-Protein Interactions	1.0	null
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47225
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FUS	Pathway Commons Protein-Protein Interactions	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K57517066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47433
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06483
CLP1	Pathway Commons Protein-Protein Interactions	1.0	null
CCT4	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14101_KO_ARID1A_SRP355686	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANXA11	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1187_KD_BCL6_SRP187038	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.57814
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32308
IALM	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
TRIP13	Pathway Commons Protein-Protein Interactions	1.0	null
GSE217156_2_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89719122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10362
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23267
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98156994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16734
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1041
MAPKAPK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.003408
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5236-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUBA1C	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10938
MRE11A	Pathway Commons Protein-Protein Interactions	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_14100_KO_ARID1A_SRP355686	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874639
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.13368
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86907
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.84689
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinocerebellar ataxia type 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-C1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.952
BRD-K06313694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24709
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PABPN1	Pathway Commons Protein-Protein Interactions	1.0	null
myclobutanil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94372
BRD-K03736784_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.38185
ARF4	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5928-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14758
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
ETF1	Pathway Commons Protein-Protein Interactions	1.0	null
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77238
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26346
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23501
DAOY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
G-401	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF696	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20852
YLPM1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0416
WDR33	Pathway Commons Protein-Protein Interactions	1.0	null
DHX8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14821
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26859
PTEN_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	5.05182
RAVER1	Pathway Commons Protein-Protein Interactions	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
YWHAH	Pathway Commons Protein-Protein Interactions	1.0	null
EMX2_Deficiency_GDS3173_607_mouse_Embryonic urogenital epithelium - day 10.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE129772_2_v_1_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36104
PSMD13	Pathway Commons Protein-Protein Interactions	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.049667
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6828
pioglitazone_rattus norvegicus_gpl1355_3 months_gds4019	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21474
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28072
BRD-K95810752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26841
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73319967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03281
propantheline bromide-4798	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62S-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0493
Perturb_13190_KO_Wnt5a_SRP346437	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.74073
TSPAN7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00696151
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4717-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06563
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.67419
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73049
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.976546
BRD-K48029682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11343
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.940437
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91783
KP2	DepMap CRISPR Gene Dependency	1.0	2.56512
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11843
Perturb_18281_KO_Ndp_SRP182592	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.4259
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19505
MYO15B	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03919
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36342
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3145-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LS123	DepMap CRISPR Gene Dependency	1.0	4.16389
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCF11	Pathway Commons Protein-Protein Interactions	1.0	null
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.839631
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890484
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.91383
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28805
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827365
TAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537521
BF-79-GG96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292961
GSE191015_1_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
XPO6	Pathway Commons Protein-Protein Interactions	1.0	null
secalciferol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90247
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	0.861209
butyl hydroxybenzoate-4647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852128
hsa-miR-3611	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
DKC1	Pathway Commons Protein-Protein Interactions	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.958528
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EC-GI-10	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.42617
OSRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.58466
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZQ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89399989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02171
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493143
hsa-miR-1912	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2228
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151119_3_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TSG101	Pathway Commons Protein-Protein Interactions	1.0	null
NOL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19088
CTNNA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Regulation of HSF1-mediated heat shock response	Reactome Pathways 2024	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06125
EIF3H	Pathway Commons Protein-Protein Interactions	1.0	null
CLNS1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K87541124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50895
Diabetic Nephropathy_Renal Tissue_GSE1009	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.588225
SP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04628
Prescription Drug Abuse	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_5506_KO_Nir_SRP114858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
KASUMI1	CCLE Cell Line Gene CNV Profiles	1.0	1.38474
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-42-YI34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218369
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
prednicarbate-5119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13459
PRCC	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1257	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10264
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	1.69836
DU-4475	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.06763
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen	HPA Tissue Protein Expression Profiles	1.0	0.861178
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
atp binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03295
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K60123410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32107
SLC1A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00364363
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21581
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
SNRPD3	Pathway Commons Protein-Protein Interactions	1.0	null
HUWE1	Pathway Commons Protein-Protein Interactions	1.0	null
HTT-18923047-STHDH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
fluoxetine_mus musculus_gds2803	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.963555
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993005
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09559
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cellular responses to stress	Reactome Pathways 2024	1.0	null
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Embryo Loss	CTD Gene-Disease Associations	1.0	1.06844
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.836032
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932627
BCAS2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K11419664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95897
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998532
AURKA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00515
TP53-16413492-HCT116-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6366065-13075_2019_1816_MOESM1_ESM.xlsx-DOD_Skin_imputed_log2_median_ce-Name_PIN1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S6.xlsx-EMP_CREB_Targets-symbol_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	Pathway Commons Protein-Protein Interactions	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04765
BRD-K59149254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32864
TAF15_02_140	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.77761
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BID	Pathway Commons Protein-Protein Interactions	1.0	null
U2AF2	Pathway Commons Protein-Protein Interactions	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7801
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-P53_DN_V1_DN-Gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41347678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49109
DDX1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907735
POLR3E	Pathway Commons Protein-Protein Interactions	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	0.921786
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
STAG1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3382-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965229
BRD-K73899643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42133
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01883
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.082234
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065821
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.97234
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15526
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932627
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969276
frontal	GeneRIF Biological Term Annotations	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898461
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39128
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17067
ZC3H18	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04336
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1264	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38047
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95304
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUMA1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4782
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942649
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06698
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.853456
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
DOCK8	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922401
hsa-miR-591	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38370827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29876
Perturb_11771_KO_10M04Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57877
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64602559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54762
BRD-K04722226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83999
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03786
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41649
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gastrointestinal system cancer	GWASdb SNP-Disease Associations	1.0	0.177989
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Perturb_1188_KD_BCL6_SRP187038	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.60997
Liver Diseases	CTD Gene-Disease Associations	1.0	1.56607
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106146
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K27067020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88257
GSS	CCLE Cell Line Gene Expression Profiles	1.0	2.00807
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-SI-A71P-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL7C	Pathway Commons Protein-Protein Interactions	1.0	null
Ciliary neurotrophic factor receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74426
chr10_116743139_G_C_b38	GTEx eQTL 2025	1.0	1.05198
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB65-RCC	GDSC Cell Line Gene Expression Profiles	1.0	1.64252
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35822
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98288
EIF4G2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K19039329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12919
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32094
SART1	Pathway Commons Protein-Protein Interactions	1.0	null
GTF3C4	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8305_KO_GALNT1_ERP012063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.2727
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36001
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
RNF17	Pathway Commons Protein-Protein Interactions	1.0	null
DIDO1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ITPKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00629729
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827737
GSE203308_6_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cognition	HuGE Navigator Gene-Phenotype Associations	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.08447
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13175
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82324807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57502
PTPN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00431319
hsa-miR-555	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7203
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC9314667-Table_1.xlsx-Regulons-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K00717406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17784
Rabies CVS-11_7day-Brain_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.59186
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Waist circumference adjusted for body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
AZIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515903
THOC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
CCNB1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29113
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02401
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48494
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43786
Drug dependence	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.012
ASUN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AP3M1	Pathway Commons Protein-Protein Interactions	1.0	null
DC-05-LU10_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215117
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
BUB1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
Tek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
DPF2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7428-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58813
hsa-miR-1294	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37013
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34507
GSE148692,GSE148695_1_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_1_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84366
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09844
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12416
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28214
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K14732209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12896
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.838543
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3663-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-4677-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
BRD-K30105551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4988
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44088
BRD-K77207661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1192
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875129
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906614
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	0.979492
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K43387144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23658
BRD-K47160864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04345
BRD-K85776843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15815
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12561
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05276
Perturb_6536_KO_Cldn5_SRP305395	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.4289
resveratrol-5509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77908580_entinostat_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AP3D1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.041387
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
Perturb_6562_KO_Zfp423_SRP105097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.30977
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DFNA5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19168792-TableS2	GeneSigDB Published Gene Signatures	1.0	null
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01847
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4627-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-1426-SM-3LK5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925732
TNFSF11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0081906
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34637
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE148252_0_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRSF1	Pathway Commons Protein-Protein Interactions	1.0	null
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
NF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00622264
YWHAQ	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57587
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288424
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42371
BRD-K79267333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30219
JEKO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.18664
H3255	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22292
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0657
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.86764
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.892083
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_11_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIF11	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYGO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596706
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.045874
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ATR	Pathway Commons Protein-Protein Interactions	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.43809
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843938
BRD-K44100512_KIN001-043_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826744
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
VASP	Pathway Commons Protein-Protein Interactions	1.0	null
HT	GDSC Cell Line Gene Expression Profiles	-1.0	-2.01091
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13390322_AT-7519_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68401
Loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23353
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4195
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.64
SIN3A	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46612
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.958613
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1X3-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11790_KO_Cd109_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.18246
CNOT10	Pathway Commons Protein-Protein Interactions	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.99764
Perturb_8946_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.1559
BRD-K26443253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30838
PF-00539745-00-5974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP18	Pathway Commons Protein-Protein Interactions	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51146
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948634
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11209
CRCGN017_MCF10A.WT.HP_24H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0931
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLGB1	Pathway Commons Protein-Protein Interactions	1.0	null
EHD1	Pathway Commons Protein-Protein Interactions	1.0	null
RIOK1	Pathway Commons Protein-Protein Interactions	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.20535
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.720491
SF3A2	Pathway Commons Protein-Protein Interactions	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839757
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.13713
ELF2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35836
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040726
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02759046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02685
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.26455
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328157
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FYTTD1	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
EIF4A2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K18801549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13057
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069194
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00014
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26675
BRD-K46811723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5458
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07853
palate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.699444
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5303304-13073_2017_407_MOESM3_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S2_Genes_differentially_expressed_by_24h_RA_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAP2K4	Pathway Commons Protein-Protein Interactions	1.0	null
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9707
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16117
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.07771
SLCO4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514972
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999589
ARID1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K11476310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08076
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07193
RNF19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00394
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_60_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08719
hsa-miR-4456	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-A93436351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85808
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
BRD-K01639528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73156
DMS273	CCLE Cell Line Gene Expression Profiles	1.0	1.39464
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.4925
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.999215
hsa-miR-619	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9643
MCF7_Mocetinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00793683
BRD-K43872193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63436
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20284960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0613
A549_Sirtinol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138895
Perturb_18559_KD_Epas1_SRP049514	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.286
Perturb_2548_KO_MLL3_SRP163132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.42463
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.992564
muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03008
PSMD3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90962
GATAD2B	Pathway Commons Protein-Protein Interactions	1.0	null
RFC4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
EIF2S2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206784_2_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	1.0	1.08539
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ECT2	Pathway Commons Protein-Protein Interactions	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
DDX19A	Pathway Commons Protein-Protein Interactions	1.0	null
EW-12	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57895
BRD-K16705729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16968
GSE71385_1_v_2_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_16480_KO_Ring1a/Ring1b_SRP136563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.65331
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27404
CBX3	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.18977
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939115
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1239
BRD-K60635455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75681
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932451
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12464
BRD-K50234570_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28062
foxa1_23539448_lncap_lof_human_gpl10558_gse37314	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.480402
UBTF	ENCODE Transcription Factor Targets	1.0	null
TGFB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559336
BRD-K31720099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22593
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00858
GM2313	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.844277
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22663
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03805
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0913
SNRPB2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27468
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16087_KD_Pml_SRP306364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.37559
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43240808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04712
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OC-10-FB51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28913
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34893
CCNT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19376
Inflammation	CTD Gene-Disease Associations	1.0	1.70533
PFKM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99690279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15341
Panobinostat_HepG2/C3A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0086851
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37133
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CMAH_KO_GDS4200_114_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51419
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-KLF5_Direct_Targets_PDAC_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44019
TRUB1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_234_KD_MITF_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.1783
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84932026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33224
PMC4595011-pgen.1005555.s002.xlsx-MITF_DOWN_in_30kb-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1914
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13299
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.81657
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr10_116692188_T_C_b38	GTEx eQTL 2025	1.0	1.48814
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UNC45A	Pathway Commons Protein-Protein Interactions	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23487
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053313
BRD-K85456600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01492
BRD-K43989220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04282
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.098308
Perturb_15017_KI_Stat6_SRP374172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.53904
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01076
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11003
MDST8_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.9359
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48861
BRD-K91766181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20884
tretinoin_mus musculus_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EHD4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944516
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUIT2	CCLE Cell Line Gene CNV Profiles	1.0	1.84008
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.09329
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1039
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NACC1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL13	Pathway Commons Protein-Protein Interactions	1.0	null
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-512-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CPSF4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914901
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.59122
ATAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00466076
BRD-K13110820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0386
L-540	GDSC Cell Line Gene Expression Profiles	-1.0	-2.03454
KHDRBS1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
peritoneal macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432991
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833814
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847339
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.897839
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.947918
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Triamcinolone_HepG2/C3A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0190978
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964807
CRCGN017_MCF10A.WT.HP_24H:H11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74375
chr10_116696503_C_T_b38	GTEx eQTL 2025	1.0	1.36556
NR0B1	ChEA Transcription Factor Targets	1.0	null
P53_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3611	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Perturb_6199_KO_Elp3_SRP065804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.271
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90433
HDLBP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4481	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15011
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326608
BRD-K90205159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43431
BRD-K52989901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11531
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.86275
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neoplasm of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.194071
BRD-K32423836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2574
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.443379
COPS6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58433
hsa-miR-4679	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44549496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90108
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
UF-14-LK87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23085
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.11687
PUM1	Pathway Commons Protein-Protein Interactions	1.0	null
MPP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63158
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007211
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.983931
MOLM6	CCLE Cell Line Gene CNV Profiles	1.0	1.36584
EIF3G	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K49040541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39366
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PKP3	Pathway Commons Protein-Protein Interactions	1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.077779
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44085
BRD-K14163107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5581
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01641
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDK11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10691
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999924
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17114
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80751
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06517
GTEX-WFG7-2426-SM-3GIL2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972787
Fatty Liver	DisGeNET Gene-Disease Associations	1.0	null
chloroxylenol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81167
Glioblastoma	CTD Gene-Disease Associations	1.0	1.06734
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828649
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLINT1	Pathway Commons Protein-Protein Interactions	1.0	null
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LRWD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE133087_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.917428
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48627
MTA3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9973
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Barber-Say syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JF-96-HH81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230733
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683744
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20024
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18592
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
doxorubicin_homo sapiens_gpl550_gds845	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906614
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24134
BRD-A21891180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16839
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
todralazine-5512	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37013
Phosphopyruvate hydratase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.967
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894629
BRD-K71824916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31904
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K27154831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30187
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	Pathway Commons Protein-Protein Interactions	1.0	null
MCM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00732913
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.2791
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.494
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16485
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL8	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6940_KO_Rbm20_SRP403612	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.3458
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.85228
bortezomib_homo sapiens_gpl10558_gds4089	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFE2L2_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869952
GSE216043_10_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16829
Perturb_13392_KD_NSD2_SRP231443	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.27151
Perturb_16580_KO_Ep300_SRP174041	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.51141
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.159971
TEX14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00452692
PTBP3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-767-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41408
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7526
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.49018
JHH4	CCLE Cell Line Gene Expression Profiles	1.0	1.49167
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP2R1A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9314667-Table_1.xlsx-Regulons-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924721
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955592
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
PPM1D	Pathway Commons Protein-Protein Interactions	1.0	null
ACTR2	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874639
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04717
CDC23	Pathway Commons Protein-Protein Interactions	1.0	null
griseofulvin-7363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09105
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NOD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588145
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.874632
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.077276
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.01008
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48332
KDM8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00392913
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1602
hsa-miR-4661-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K57969360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69779
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12478
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040465
TT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
BL2837 (UIMC1)	NURSA Protein Complexes	1.0	null
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13848_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_12_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MSH6	Pathway Commons Protein-Protein Interactions	1.0	null
DYRK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710258
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
increased insulin sensitivity	MGI Mouse Phenotype Associations 2023	1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
BT20	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28681
BRD-K64264263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23984
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hereditary spastic paraplegia 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07382
HBS1L	Pathway Commons Protein-Protein Interactions	1.0	null
NUPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00459967
SKIV2L2	Pathway Commons Protein-Protein Interactions	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27878
BRD-K97241181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18762
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09382
Ebolavirus(EBOV)_6day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.195752
MTA2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07908
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18575
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5096-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01071579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25189
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2254
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958383
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81288338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20969
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
RPL22	Pathway Commons Protein-Protein Interactions	1.0	null
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2638
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98288
SRRM2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K36737713_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45553
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826339
PARVA	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
BCLAF1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55793
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
strongest	GeneRIF Biological Term Annotations	1.0	null
SLC25A22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062329
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13413
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDLRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12547363-CTS-18-e70350-s001.pdf-64-ZNF423_ZNF423	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
20502458-TableS6c	GeneSigDB Published Gene Signatures	1.0	null
bufexamac-7413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856161
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0255
hsa-miR-4684-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.87155
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00194
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994911
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
HCC78	DepMap CRISPR Gene Dependency	1.0	2.33278
NCIH1755	DepMap CRISPR Gene Dependency	1.0	2.62399
BRD-K44537081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50572
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914539
WDR77	Pathway Commons Protein-Protein Interactions	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87204
TAF1	ENCODE Transcription Factor Targets	1.0	null
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98355012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5533
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.20862
MYOD1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01762
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0237
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.062087
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928308
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92607052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25257
GSE193354_0_v_1_saraf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.72322
hsa-miR-197	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Carcinoma	CTD Gene-Disease Associations	1.0	1.03641
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
xamoterol-3064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858156
Lung adenocarcinoma_LUAD_TCGA-97-8176-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6413
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.83164
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MLLT3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4136
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19775
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05181466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26973
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932627
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32206
FOXA2	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.908891
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LAN-6	GDSC Cell Line Gene Expression Profiles	1.0	2.44584
BRD-K10196668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08677
TTK	Pathway Commons Protein-Protein Interactions	1.0	null
PSMC1	Pathway Commons Protein-Protein Interactions	1.0	null
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31241
Neoplasms	CTD Gene-Disease Associations	1.0	1.60267
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH524	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87227
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C75	DepMap CRISPR Gene Dependency	1.0	2.35326
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958869
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
IKBKAP	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M3-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_6299_KD_CGA_SRP355115	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19858
LDLRAD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00756626
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RNF130	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11420482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48498
BRD-K95455263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16749
schizophrenia	GeneRIF Biological Term Annotations	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.902006
haloperidol-6960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.15526
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6823-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEPG2	BioGPS Cell Line Gene Expression Profiles	1.0	0.92889
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3652	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20597
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95338817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79116
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12196
BRD-A43135847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36446
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838698
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36608
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30734
UOK101	CCLE Cell Line Gene Expression Profiles	1.0	2.48816
reduced	GeneRIF Biological Term Annotations	1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-B_FUS-DDIT3-eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80984
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OLIG2	ChEA Transcription Factor Targets	1.0	null
GTF2I	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_ATF3_PanPC_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K63996931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06666
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6078853-molce-41-7-695-suppl2.xlsx-Sheet1-Table_S1_Genes_exhibiting_two-fold_changes_in_expression_between_WT_and_CTCF_KO_otocyst_with_FDR_less_than_0_05_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61481
BRD-K73357447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41787
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058728
KDM5A-27292631-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.044
chr10_116734247_T_C_b38	GTEx eQTL 2025	1.0	1.28563
GTPBP1	Pathway Commons Protein-Protein Interactions	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26997
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-5047	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A29371732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98005
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972913
BRD-U61997977_WZ-4-145_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06781
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K92632379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63833
SNX20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507245
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.95066
substance-related disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.012
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86693
EXOSC10	Pathway Commons Protein-Protein Interactions	1.0	null
TNPO1	Pathway Commons Protein-Protein Interactions	1.0	null
Colorectal Cancer	DisGeNET Gene-Disease Associations	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041188
SRSF7	Pathway Commons Protein-Protein Interactions	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.08315
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965467
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6919
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMEM60	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673072
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CSK	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31239
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPB41L3	Pathway Commons Protein-Protein Interactions	1.0	null
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43455
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0057
G3BP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0571
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900437
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914044
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.456
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20168
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.415
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04053
Golgi apparatus	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0506
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06544
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4260_OE_MEIS1_SRP201342	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.56173
Corpuscular Hemoglobin Concentration Mean	DisGeNET Gene-Phenotype Associations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29722
PPARG	ChEA Transcription Factor Targets	1.0	null
PSMC4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.745477
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD4	Pathway Commons Protein-Protein Interactions	1.0	null
DDX46	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETD1A	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRPF4B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56055036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26634
BRD-K24848743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25606
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874493
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874639
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spastic ataxia 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
PNN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.953546
RCOR1	Pathway Commons Protein-Protein Interactions	1.0	null
U2AF1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.55448
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1036
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.554
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TIPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539449
SNU398	CCLE Cell Line Gene CNV Profiles	1.0	1.44165
PIK3R4	Pathway Commons Protein-Protein Interactions	1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068783
ITGAX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00454107
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-410	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65679
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	2.27227
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CKAP5	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A464-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1792	DepMap CRISPR Gene Dependency	1.0	2.0411
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
GSE197342_2_v_0_berberine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52977
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.73618
ABCF1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_944_KO_Bhlhe40|Bhlhe41_SRP216680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.22614
POLE	Pathway Commons Protein-Protein Interactions	1.0	null
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936094
PBRM1	Pathway Commons Protein-Protein Interactions	1.0	null
CHEK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00880579
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.97234
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50433
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11843
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UMPS	Pathway Commons Protein-Protein Interactions	1.0	null
lovastatin-2494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27026
Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A77164655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58972
GSE225869_1_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46455
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6811834-sby183_suppl_supplementary_data_set_1.xls-ZNF804A_DEX_FDR_0_01-Gene_Symbol_ZNF804A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55382
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3186-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985061
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88206
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31812
GSE233679_5_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921763
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43257
DOCK1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4683	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02866
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2S	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1301	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S5-Supplemental_Table_S5_Genes_commonly_downregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
RPL3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926668
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9011
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3376
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921473
VPRBP	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YWHAB	Hub Proteins Protein-Protein Interactions	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874639
BRD-K47087435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27595
EXOC3	Pathway Commons Protein-Protein Interactions	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92948
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95609
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4268	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.05447
LU65_LUNG	CCLE Cell Line Proteomics	1.0	4.50121
TWF1	Pathway Commons Protein-Protein Interactions	1.0	null
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144484_0_v_1_mllt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23582
SCAF8	Pathway Commons Protein-Protein Interactions	1.0	null
LYAR	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	2.26868
BRD-K91060460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02059
ZNF263	ENCODE Transcription Factor Targets	1.0	null
BRD-K79202867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70701
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844791
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BABAM1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95735171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34974
FANCD2	Pathway Commons Protein-Protein Interactions	1.0	null
ZC3HC1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP107	Pathway Commons Protein-Protein Interactions	1.0	null
UPF1	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07017
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.43531
GSE130401_6_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54459
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52929
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06785
BRD-K67120755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36394
Perturb_4413_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_16916_KD_Maf1_SRP375944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.99033
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.488
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63941
BRD-K16598630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22219
NCIH2444	CCLE Cell Line Gene CNV Profiles	1.0	1.82999
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05543
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PICALM	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344506
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.10635
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Substance Dependence	DisGeNET Gene-Disease Associations	1.0	null
GSE116492,GSE116495_3_v_1_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50950731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93803
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33656
BRD-K09598619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42679
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
hsa-miR-4633-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.990092
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02452
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831502
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.61944
GTEX-T6MO-1726-SM-33HB8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842309
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101546_2_v_1_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26451
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
PIK3R5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608048
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70029
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53665
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891128
Edema	CTD Gene-Disease Associations	1.0	1.31867
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829443
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10592962-media-4.xlsx-OC2_genes-gene_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3158-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
MAGEE2	Pathway Commons Protein-Protein Interactions	1.0	null
RAB11FIP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00487113
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12802
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222721
HAUS7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15898103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36453
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
transcript	GeneRIF Biological Term Annotations	1.0	null
USO1	Pathway Commons Protein-Protein Interactions	1.0	null
IDH3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00803549
Medroxyprogesterone acetate_HepG2/C3A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0135453
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.923966
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.4267
INTS1	Pathway Commons Protein-Protein Interactions	1.0	null
SRSF6	Pathway Commons Protein-Protein Interactions	1.0	null
GPS2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63177
BRD-K95500312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17308
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70499_3_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
colorectal cancer	GWASdb SNP-Disease Associations	1.0	1.20161
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.934655
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLASP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972703
BRD-K45428339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20022
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20097
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01519
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE56235_1_v_0_prdm11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.65402
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPA0	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03315
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A41916216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.153
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55814
EIF2S1	Pathway Commons Protein-Protein Interactions	1.0	null
PAX3_01_27	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.9817
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56554
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21205
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10142
LIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
TAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29664
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.97234
Ascites	CTD Gene-Disease Associations	1.0	1.22664
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.825183
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051666
increased cerebral infarct size	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76981
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH446	DepMap CRISPR Gene Dependency	1.0	2.16695
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5367-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04039
RFX5	ENCODE Transcription Factor Targets	1.0	null
Colorectal Cancer	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936094
cancer	GWASdb SNP-Disease Associations	1.0	0.050552
PMC10993403-ao4c00373_si_001.pdf-20-ZNF610_ZNF610	Rummagene Transcription Factor Associations 2026	1.0	null
NAF1	Pathway Commons Protein-Protein Interactions	1.0	null
TUHR4TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.60143
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
KTI12	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3619-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP3B1	Pathway Commons Protein-Protein Interactions	1.0	null
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.16799
EIF2B4	Pathway Commons Protein-Protein Interactions	1.0	null
GNA14	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K82781769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01691
RPS14	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
canavanine-4782	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00408809
BRD-K08647020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38032
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20659
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAD1L1	Pathway Commons Protein-Protein Interactions	1.0	null
chr10_116704232_T_C_b38	GTEx eQTL 2025	1.0	1.49853
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74952
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77459
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.65549
BRD-K86155400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09426
BRD-K92513859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18921
intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.117759
CHD2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ILK	Pathway Commons Protein-Protein Interactions	1.0	null
AB-17-WP43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216717
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14135
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95682
MYBBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DOCK2	Pathway Commons Protein-Protein Interactions	1.0	null
SF3B4	Pathway Commons Protein-Protein Interactions	1.0	null
MEF2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626915
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2845
PELO	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32522318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24785
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7065-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67403750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2267
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03621
GSE242083,GSE242098_3_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Multiple Myeloma	CTD Gene-Disease Associations	1.0	1.06588
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1184
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06831
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-46-GL76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260336
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08209
BRD-K23960050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0393
MAP2K2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-498	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
hsa-miR-4708-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K32893898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18525
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22054
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IDRA-21	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28578
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74593
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL23A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28892
Perturb_15069_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47794327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03484
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ankylosing Spondylitides_macrophage_GSE11886	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.71876
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
VA-ES-BJ	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.12599
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BL2805 (UBR5)	NURSA Protein Complexes	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41896
hsa-miR-378h	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNW1	Pathway Commons Protein-Protein Interactions	1.0	null
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2956
BRD-K91654198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60466
RFX5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K70566686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04867
A549_Baricitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143041
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18339
BRD-K48670593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25929
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40223
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18068
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81402
CRCGN015_HEPG2_48H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09615
BRD-K98940411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78223
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0326
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997692
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84645
PPFIA1	Pathway Commons Protein-Protein Interactions	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904891
BRD-K76922696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05106
MOLP8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81679
SF3B2	Pathway Commons Protein-Protein Interactions	1.0	null
chr10_116743080_C_CCGCAGACCAAGGA_b38	GTEx eQTL 2025	1.0	3.22466
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
sulfametoxydiazine-5732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Longissimus lumborum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837117
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33288
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01687
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33834
cisplatin_homo sapiens_gpl6480_gse33482	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16994
SRP72	Pathway Commons Protein-Protein Interactions	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
Renal Insufficiency	CTD Gene-Disease Associations	1.0	1.30087
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.236988
procaine-5430	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
KMT2D	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04085
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52885
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40192
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33273
BRD-K85275903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.78525
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	2.13245
RANBP9	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-338-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
VANGL1	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858658
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP48	Pathway Commons Protein-Protein Interactions	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
BRD-K26108750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53818
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07438
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B4-01A-12R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
BRD-K19523047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49398
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.319
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661576
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2F2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UN-AAZ9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral group of nuclei, left, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74236
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.56304
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04038
BRD-K83109105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29151
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K75738997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49696
EP300	ENCODE Transcription Factor Targets	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
BRD-K92904754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07489
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.97234
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38529
BRD-K83673542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09301
ATRX	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5413166__F5	PFOCR Pathway Figure Associations 2024	1.0	null
ACTR1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K35923751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21687
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06442
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937771
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936581
DNAJC13	Pathway Commons Protein-Protein Interactions	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21697
NOLC1	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7471
GSE138872,GSE138874_0_v_1_il33_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144484_0_v_3_mllt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96365
786	BioGPS Cell Line Gene Expression Profiles	1.0	0.969698
hsa-miR-4445	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18309
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98845
TAF15	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K26161397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06792
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.827295
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53258
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15507
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
PANX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548296
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39022
MORF4L2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.847227
BRD-K47467075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07018
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982184
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19044
MAPK14_KD_GDS2693_533_mouse_A431	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7243-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vertical cup-disc ratio (multi-trait analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE238018_1_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
XRCC5_02_159	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.85798
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.38365
BRD-K94306568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26487
rilmenidine-5107	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IPO7	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0612
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEMA4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10979
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20076
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07399
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42799
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K98856654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42785
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.728628
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908445
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24184
BRD-K68118416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70767
intestinal cancer	GWASdb SNP-Disease Associations	1.0	0.499367
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.554
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.896785
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87347
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.06114
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A101D	GDSC Cell Line Gene Expression Profiles	1.0	1.73604
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
SF3A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BACH1	ChEA Transcription Factor Targets	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
esrra_19901197_kidney_lof_mouse_gpl1261_gse16623	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.063356
BRD-K56879482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22418
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.16822
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15051
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7771094-12920_2020_832_MOESM5_ESM.txt--ATF2_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38869
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01797
ACTL6A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.71973
CEBPD	ENCODE Transcription Factor Targets	1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4685
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXRA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621607
Colorectal cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73475697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1227
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78772
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
distribution	GeneRIF Biological Term Annotations	1.0	null
CHD4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K98087319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04995
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC23B	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53848
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53277
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846707
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36838
MDN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165548_2_v_7_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
INTS12	Pathway Commons Protein-Protein Interactions	1.0	null
TE11_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	8.22344
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6492
BCLAF1_02_142	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.75489
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.88214
RBM15	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19429
VPS33A	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04628654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.90033
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51107
SNU1272	CCLE Cell Line Gene Expression Profiles	1.0	1.64093
RAD21	Pathway Commons Protein-Protein Interactions	1.0	null
WRNIP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13969
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042431
BRD-K74236049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19287
BUB3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37931645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05653
RFC3	Pathway Commons Protein-Protein Interactions	1.0	null
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84048601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50984
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K01759041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25132
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26469
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58092
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87461415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42512
Ablepharon macrostomia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A-CA-04-2009(H1N1)_48Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41624
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046576
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
NCOR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137653_4_v_0_siglecf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10084
brain	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832602
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84586608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26177
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1927
PTEN_KD_GDS2958_99_human_A431 - EPIDERMOID carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CNOT1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_14378_KD_PAX8_SRP276625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.49815
BRD-A19500257_geldanamycin_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MVP	Pathway Commons Protein-Protein Interactions	1.0	null
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.038573
DDX19B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88936403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80442
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32083
flavoxate-5427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836571
ITPK1	Pathway Commons Protein-Protein Interactions	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48963
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83903
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051906
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Longissimus thoracis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.07701
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
ovary	HPA Tissue Gene Expression Profiles	1.0	0.84114
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1455
NCIH441_LUNG	CCLE Cell Line Proteomics	1.0	2.48612
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64641
decreased susceptibility to diet-induced obesity	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
QRICH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00827553
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17551
RBM7	Pathway Commons Protein-Protein Interactions	1.0	null
Abdominal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68416
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38345640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53729
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
hsa-miR-4428	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
DTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04756
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49626
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
SRSF4	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hepatopancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.810638
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K05786443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14124
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37218
BRD-K97452545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59113
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7104-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74689
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87387
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.77692
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
MT-ND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25975
MPZL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00406138
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85807
BRD-K90349877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3494
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCC1	Pathway Commons Protein-Protein Interactions	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30888
RPL12	Pathway Commons Protein-Protein Interactions	1.0	null
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866789
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846261
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.36395
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840027
KPNA1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPA1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057761
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.31756
PARP4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Unipolar Depression	DisGeNET Gene-Disease Associations	1.0	null
THAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
BRD-K18176829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20588
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
KYSE30_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.51359
BRD-K47801291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56844
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27768
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
BRD-K70735803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58784
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS26	DepMap CRISPR Gene Dependency	1.0	2.1612
BRD-K02078126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7784
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EOMES-21245162-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52569
Perturb_4205_KO_Top1_SRP072888	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.61319
Sacrospinalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5413166__F5	PFOCR Pathway Figure Associations 2023	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21339
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30359
WDR18	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A12372458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25238
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225103
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15148
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STK24	Pathway Commons Protein-Protein Interactions	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.27011
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPA3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44933
Methyl aminolevulinate (hydrochloride)_AN3 CA	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0182161
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.637
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15318_KO_Setd2_SRP199112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.6097
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254212
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57494
NCIH1694	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02762
MARK2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TMPO	Pathway Commons Protein-Protein Interactions	1.0	null
GSE115763_3_v_1_klf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25273
BRD-K26079895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10374
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860089
SNRPA1	Pathway Commons Protein-Protein Interactions	1.0	null
NIPBL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86797399_pracinostat_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SRSF11	Pathway Commons Protein-Protein Interactions	1.0	null
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Right atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.078
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60854
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
shows	GeneRIF Biological Term Annotations	1.0	null
GSE129244_0_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12068
BRD-K90133009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78396
RBM45	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Nintedanib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151588
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3661	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
KDM1A	Pathway Commons Protein-Protein Interactions	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34995
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LILRA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00791604
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08881
BRD-K83699731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46774
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13105
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69214
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.0766
PIP4K2A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Colorectal cancer	GWAS Catalog SNP-Phenotype Associations	1.0	0.22914
C7orf13	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_9479_KO_Mecp2_SRP154883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.48892
ZNF326	Pathway Commons Protein-Protein Interactions	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JAK2_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4725-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42Q-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
WSU-DLCL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970836
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851353
RUVBL2	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Ellagic acid_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191867
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.552
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DOHH-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43542
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.032339
OXSR1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89253
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239844_4_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10385
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12656
RIF1	Pathway Commons Protein-Protein Interactions	1.0	null
P2RY4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620718
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57462
PMC6487024-13148_2019_658_MOESM2_ESM.xlsx-S3-ADNP-1_DMRs-Unnamed_11_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUF2	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18118
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuron	GeneRIF Biological Term Annotations	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22719
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4710	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4703-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null