association	dataset	threshold value	standardized value
chemotherapyinduced	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmitter-gated monoatomic ion channel activity	GO Molecular Function Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J4-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
sodium arsenite	CTD Gene-Chemical Interactions	1.0	null
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.421148
COLO679	DepMap CRISPR Gene Dependency	1.0	2.1179
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.428
Esophageal carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
Nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
Ligand-gated ion channel transport	Reactome Pathways 2014	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36369
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77188
Cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990426
496100528_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62475
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29411
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17485
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4041
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45R-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.296571
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
single-organism localization	GO Biological Process Annotations 2015	1.0	null
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0694
dyspepsia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.681096
UOK101	DepMap CRISPR Gene Dependency	1.0	3.21876
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stress Disorders, Traumatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
neuron projection	GO Cellular Component Annotations 2025	1.0	null
Vomiting	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99206
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
PPP3CA	Pathway Commons Protein-Protein Interactions	1.0	null
SLC17A7	Pathway Commons Protein-Protein Interactions	1.0	null
htr3a	GeneRIF Biological Term Annotations	1.0	null
MYH11	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A615-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913056
SLVL	DepMap CRISPR Gene Dependency	1.0	18.1241
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00985
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49024
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31791
Esophageal cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44737
Transmission across Chemical Synapses	Reactome Pathways 2024	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	150.614
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053553
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6019
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055036
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893265
hsa-miR-4688	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6975
MYH6	Pathway Commons Protein-Protein Interactions	1.0	null
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.39358
DNAJC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97685
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866624
TPM2	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hsa-miR-544b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
anterograde trans-synaptic signaling	GO Biological Process Annotations 2025	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.1771
NFATC2	Pathway Commons Protein-Protein Interactions	1.0	null
Edema	HuGE Navigator Gene-Phenotype Associations	1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91154
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82039
ITGA1	Pathway Commons Protein-Protein Interactions	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.6026
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRANISETRON	DGIdb Drug Targets 2026	1.0	0.35288
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STXBP1	Pathway Commons Protein-Protein Interactions	1.0	null
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990163
496100492_TCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19391
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35148
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
extracellular ligand-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
PPP3CB	Pathway Commons Protein-Protein Interactions	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acute	GeneRIF Biological Term Annotations	1.0	null
CAL-85-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0038
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50895
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1536
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35769
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04322
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Primary angle-closure glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77096
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056293
Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H520	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23416
Personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
Mean corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26352
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2843
Adrenocortical carcinoma_ACC_TCGA-OR-A5JQ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05719
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26206
MYBPC2	Pathway Commons Protein-Protein Interactions	1.0	null
Angle Closure Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
Gastric fundus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
transmitter-gated monoatomic ion channel activity	GO Molecular Function Annotations 2023	1.0	null
well	GeneRIF Biological Term Annotations	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15316
TYSND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63663
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05405
breast neoplasms; mammary neoplasms; nausea; vomiting	GAD Gene-Disease Associations	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40381
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68691
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865238
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865238
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55059
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21536
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	2.00624
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29807
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2331
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.8392
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3207
OVMANA	DepMap CRISPR Gene Dependency	1.0	3.49512
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pregnancy Complications	HuGE Navigator Gene-Phenotype Associations	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45988
SORBS3	Pathway Commons Protein-Protein Interactions	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9835
ADHD and autism ASD pathways	WikiPathways Pathways 2024	1.0	null
PPFIA1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-2276	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.115
Nicotinic acetylcholine-gated receptor, transmembrane domain	InterPro Predicted Protein Domain Annotations	1.0	null
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.45364
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09074
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	216.238
SCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35077
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.195
risperidone	GeneRIF Biological Term Annotations	1.0	null
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868624
GRIN2D	Pathway Commons Protein-Protein Interactions	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.496
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29734
BGC823	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37455
molecular_function	GO Molecular Function Annotations 2015	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993102
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03702
TESMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89093
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZF-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868624
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56709
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6902
Primary Angle-Closure Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
Neurotransmitter-gated ion-channel ligand-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15538
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1667
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
serotonin receptor activity	GO Molecular Function Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DD-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eating disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
LC-1-SQ	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
NFATC3	Pathway Commons Protein-Protein Interactions	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18669
MAFK	ENCODE Transcription Factor Targets	1.0	null
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
USP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62768
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67902
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29807
excitatory extracellular ligand-gated monoatomic ion channel activity	GO Molecular Function Annotations 2025	1.0	null
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407453
membrane part	GO Cellular Component Annotations 2015	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05344
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61615
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.34273
Neuroactive ligand signaling	KEGG Pathways 2026	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.11181
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18589
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58372
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055973
MIH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC12587232-DOM-27-6894-s001.pdf-18-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH661	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54051
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
DOV13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78233
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80131
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57316
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
RASGRP1	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
coding	GeneRIF Biological Term Annotations	1.0	null
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49024
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHO	Pathway Commons Protein-Protein Interactions	1.0	null
EW22	DepMap CRISPR Gene Dependency	1.0	2.41914
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.01934
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21101
hsa-miR-3945	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT11284	DepMap CRISPR Gene Dependency	1.0	2.30752
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
serotonin receptor activity	GO Molecular Function Annotations 2015	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7523
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22135
RASGRP2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862265
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82628
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABA-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sleep Apnea, Obstructive	HuGE Navigator Gene-Phenotype Associations	1.0	null
risks	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06536
localization	GO Biological Process Annotations 2015	1.0	null
SYT1	Pathway Commons Protein-Protein Interactions	1.0	null
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2856
single-organism transport	GO Biological Process Annotations 2015	1.0	null
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25131
CALM1	Pathway Commons Protein-Protein Interactions	1.0	null
Major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865238
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.32557
PYGM	Pathway Commons Protein-Protein Interactions	1.0	null
TNNI3	Pathway Commons Protein-Protein Interactions	1.0	null
Ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45988
SNU475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54445
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36554
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18898
Acute Myeloid Leukemia_LAML_TCGA-AB-2949-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
PPFIA3	Pathway Commons Protein-Protein Interactions	1.0	null
PEO4	DepMap CRISPR Gene Dependency	1.0	4.01666
sleep apnea, obstructive	GAD Gene-Disease Associations	1.0	null
Irritable bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.994
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZNF286A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14335
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066025
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856626
EW-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
CNGA1	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30164
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87351
TPM1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8182-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941165
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050962
Schizophrenic Psychology	HuGE Navigator Gene-Phenotype Associations	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A23Y-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
biological regulation	GO Biological Process Annotations 2015	1.0	null
TNNC2	Pathway Commons Protein-Protein Interactions	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CALD1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7873
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3R5-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMD	Pathway Commons Protein-Protein Interactions	1.0	null
N18TG2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
18318837-TableS2	GeneSigDB Published Gene Signatures	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993102
PATU8902	DepMap CRISPR Gene Dependency	1.0	3.95285
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06358
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90583
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5186
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
POLR3A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
htr3d	GeneRIF Biological Term Annotations	1.0	null
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.888302
hsa-miR-4772-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9351
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993102
GPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84227
subunit	GeneRIF Biological Term Annotations	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PK-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4494	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTF3C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17485
anterograde trans-synaptic signaling	GO Biological Process Annotations 2023	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930539
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEG-01 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9406
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32532
gated channel activity	GO Molecular Function Annotations 2015	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	184.167
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.23184
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
BC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.12764
Adrenocortical carcinoma_ACC_TCGA-OR-A5JA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
ISTMES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93104
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.59626
MYL1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_4_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.21555
MYL4	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5ST-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psychomotor Performance	HuGE Navigator Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestine	GeneRIF Biological Term Annotations	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3712
DHRS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60279
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.45216
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82714
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.69791
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21031
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.271
cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.320451
inorganic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39009
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
FOS	ENCODE Transcription Factor Targets	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
TNNI2	Pathway Commons Protein-Protein Interactions	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6204
serotonin receptor activity	GO Molecular Function Annotations 2023	1.0	null
Oppositional defiant disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYL6B	Pathway Commons Protein-Protein Interactions	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228497
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.268
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
htr3c	GeneRIF Biological Term Annotations	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
variants	GeneRIF Biological Term Annotations	1.0	null
Neurotransmitter receptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NG-108-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
neurons	GeneRIF Biological Term Annotations	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826818
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serotonergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56944
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-70	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heroin dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14794
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C8-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Familial adult myoclonic epilepsy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
NCI-H2052	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8907
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.19
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87923
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325701
GPR27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66196
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99206
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985304
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
GRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
EVI1-22308434-SKOV3-HUMAN-OVARY-OVARIANCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4727
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
g-protein coupled amine receptor activity	GO Molecular Function Annotations 2015	1.0	null
ligand-gated monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
Neurotransmitter receptors and postsynaptic signal transmission	Reactome Pathways 2024	1.0	null
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10105
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ion channel transport	Reactome Pathways 2014	1.0	null
PYGB	Pathway Commons Protein-Protein Interactions	1.0	null
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07404
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5289
BZRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60826
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEDATIOXETINE	DGIdb Drug Targets 2026	1.0	0.3208
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SN-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
extracellular ligand-gated monoatomic ion channel activity	GO Molecular Function Annotations 2025	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998508
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865238
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95876
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050676
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4215
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
ACTN3	Pathway Commons Protein-Protein Interactions	1.0	null
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.30053
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26088
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917856
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2259
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05405
hsa-miR-4668-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07777
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2381
496100560_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17113
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.57875
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5511
HOXD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25644
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuropsychological Tests	HuGE Navigator Gene-Phenotype Associations	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4745-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
signal transduction	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EI-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01265
anthracycline	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3663-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06952
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12088
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04612
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.864175
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06536
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98153
MAFF	ENCODE Transcription Factor Targets	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848309
ligand-gated channel activity	GO Molecular Function Annotations 2015	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969458
serotonin-gated monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
shows	GeneRIF Biological Term Annotations	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LC-01A-31R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Serotonergic synapse	KEGG Pathways 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	180.921
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062679
chemotherapy	GeneRIF Biological Term Annotations	1.0	null
769-P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860453
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29411
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040136
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
20460173-ImmPortCytokineReceptors	GeneSigDB Published Gene Signatures	1.0	null
ligand-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Nausea	HuGE Navigator Gene-Phenotype Associations	1.0	null
ARL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79443
TNNT1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5497-01A-02R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39667
MYH3	Pathway Commons Protein-Protein Interactions	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
hsa-miR-3616-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
NCI-H128	COSMIC Cell Line Gene Mutation Profiles	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056611
irritable bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.22302
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCIH322	DepMap CRISPR Gene Dependency	1.0	2.13313
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.10433
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.01317
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOSAPRIDE	DGIdb Drug Targets 2026	1.0	0.588133
RAMOSETRON HYDROCHLORIDE	DGIdb Drug Targets 2026	1.0	0.70576
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71699
Cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3623
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.663181
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	1.80924
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22595
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLOTHIAPINE	DGIdb Drug Targets 2026	1.0	0.392089
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.36706
PXN	Pathway Commons Protein-Protein Interactions	1.0	null
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23935
Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.5848
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F2-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11366
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34384
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1344
MYH8	Pathway Commons Protein-Protein Interactions	1.0	null
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869911
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95467
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5526
TSPYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42604
cation channel complex	GO Cellular Component Annotations 2025	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72913
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	4.75196
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5877
Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.723
Post Stroke Depression	DisGeNET Gene-Disease Associations	1.0	null
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9625
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.17599
Somatoform disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
Parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.200982
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2582
six	GeneRIF Biological Term Annotations	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99206
JHH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6181
Mitochondrial inner membrane assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.342
Ec	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858893
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99206
CAMK2A	Pathway Commons Protein-Protein Interactions	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
ligand-gated monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A44A-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A3KAW	DepMap CRISPR Gene Dependency	1.0	3.16707
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.48596
cell part	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SQSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21527
PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FACINICLINE HYDROCHLORIDE	DGIdb Drug Targets 2026	1.0	0.588133
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5226
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9811
NCI-H1648	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
Pain disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
COPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87667
Amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.484
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pain	HuGE Navigator Gene-Phenotype Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886543
hsa-miR-501-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.041
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.855174
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRIN2C	Pathway Commons Protein-Protein Interactions	1.0	null
TPM4	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05719
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03916
SNU899	CCLE Cell Line Gene CNV Profiles	1.0	1.34271
CEBPB	ENCODE Transcription Factor Targets	1.0	null
neurotransmitter receptor complex	GO Cellular Component Annotations 2023	1.0	null
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
UPCISCC026	DepMap CRISPR Gene Dependency	1.0	3.19032
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
Caudate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
Sarcoma_SARC_TCGA-DX-A1KZ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223906
cd86 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05719
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06767
UNC13B	Pathway Commons Protein-Protein Interactions	1.0	null
PUMOSETRAG	DGIdb Drug Targets 2026	1.0	0.70576
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.8115
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74186
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNNT3	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00518
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41411
NB(TU)1-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.547326
cation channel complex	GO Cellular Component Annotations 2023	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7107
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866624
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34963
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC1	Pathway Commons Protein-Protein Interactions	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.37957
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6303
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35602
MYL12B	Pathway Commons Protein-Protein Interactions	1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991316
single-organism process	GO Biological Process Annotations 2015	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44
CAOV3	DepMap CRISPR Gene Dependency	1.0	3.16107
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956102
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.662
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70848
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919316
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.54778
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3208
HOXC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32344
NCIH1666	DepMap CRISPR Gene Dependency	1.0	4.42594
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
Attention	HuGE Navigator Gene-Phenotype Associations	1.0	null
MAPACHS77	DepMap CRISPR Gene Dependency	1.0	2.04466
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.29614
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
BFTC-909	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ischemic colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GO Molecular Function Annotations 2025	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
TCAP	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7409
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40381
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07536
Lung squamous cell carcinoma_LUSC_TCGA-56-5898-01A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	2.65597
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91154
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2899
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54033
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09648
IRX1_01_227	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59345
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89963
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935596
subunits	GeneRIF Biological Term Annotations	1.0	null
Depressive Disorder, Major	HuGE Navigator Gene-Phenotype Associations	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
CPLX1	Pathway Commons Protein-Protein Interactions	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43158
myenteric	GeneRIF Biological Term Annotations	1.0	null
C127I cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X2-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
serotonin-gated cation-selective signaling pathway	GO Biological Process Annotations 2025	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3WB-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
GRIN2A	Pathway Commons Protein-Protein Interactions	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0718
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30306
DEXFENFLURAMINE HYDROCHLORIDE	DGIdb Drug Targets 2026	1.0	0.207576
EZH2	ENCODE Transcription Factor Targets	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7053
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12103
serotonin receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
PYGL	Pathway Commons Protein-Protein Interactions	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.928583
Plasma membrane signaling receptor complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ion transport	GO Biological Process Annotations 2015	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8767
angle-closure glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
PRKCB	Pathway Commons Protein-Protein Interactions	1.0	null
differential	GeneRIF Biological Term Annotations	1.0	null
PMC5625807__F2	PFOCR Pathway Figure Associations 2023	1.0	null
769P	DepMap CRISPR Gene Dependency	1.0	2.84977
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49238
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2372
MYL2	Pathway Commons Protein-Protein Interactions	1.0	null
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22628
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE180	CCLE Cell Line Gene CNV Profiles	1.0	1.84843
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU61	DepMap CRISPR Gene Dependency	1.0	2.61066
Visual Perception	HuGE Navigator Gene-Phenotype Associations	1.0	null
MYBPC1	Pathway Commons Protein-Protein Interactions	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5179
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25511
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865238
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.27
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.586
serotonin-activated cation-selective channel complex	GO Cellular Component Annotations 2023	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04665
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06536
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.626
after	GeneRIF Biological Term Annotations	1.0	null
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.940514
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65802
PANC0504	DepMap CRISPR Gene Dependency	1.0	7.40014
MYC	ENCODE Transcription Factor Targets	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6883
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A181-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glial cytoplasmic inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
SNAP25	Pathway Commons Protein-Protein Interactions	1.0	null
LMOD1	Pathway Commons Protein-Protein Interactions	1.0	null
ITGB5	Pathway Commons Protein-Protein Interactions	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06358
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422292
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958702
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4432	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49543
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
RNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7077
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01166
Sarcoma_SARC_TCGA-DX-A48P-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	2.11186
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993102
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurotransmitter-gated ion-channel	InterPro Predicted Protein Domain Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65802
Circular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1759
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896755
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
schizophrenia	GAD Gene-Disease Associations	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
PA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NEB	Pathway Commons Protein-Protein Interactions	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44366
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53206
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GO Molecular Function Annotations 2025	1.0	null
PRKCA	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878937
serotonin-activated cation-selective channel complex	GO Cellular Component Annotations 2025	1.0	null
VAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5788
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.704
C99	DepMap CRISPR Gene Dependency	1.0	2.24258
KYSE70	CCLE Cell Line Gene CNV Profiles	1.0	1.95914
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80219
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50499
Colon sigmoideum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77085
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49543
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054876
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29653
LS-123	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75146
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4253
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5913
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23271
CNGB1	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17571
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.29332
UMUC9	DepMap CRISPR Gene Dependency	1.0	2.34737
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40695
TE-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCCIT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842672
hsa-miR-3128	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GRIN2B	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	2.58967
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6561
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Esophagus adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05008
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49865
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8052
Cognition Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4937
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.9923
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5
RDES	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46306
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.916487
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4732
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28882
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.42919
membrane	GO Cellular Component Annotations 2015	1.0	null
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH520	CCLE Cell Line Gene CNV Profiles	1.0	2.06218
hsa-miR-2276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81253
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050654
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC5625807__F2	PFOCR Pathway Figure Associations 2024	1.0	null
496100588_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53825
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944506
TNNC1	Pathway Commons Protein-Protein Interactions	1.0	null
MYL9	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0335
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.386308
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.887681
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70708
PPP3R1	Pathway Commons Protein-Protein Interactions	1.0	null
Smooth endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	147.063
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3231
GTF3C2	ENCODE Transcription Factor Targets	1.0	null
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	5.89718
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100498_PCx_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87735
Obsessive-Compulsive Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24814
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.1366
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.661594
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	6.34977
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35769
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33392
YY1	ENCODE Transcription Factor Targets	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01265
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.63648
MOLM-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.34082
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1331
Anterior chamber depth	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835592
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27201
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49543
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78001
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1197
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895882
neurotransmitter receptor complex	GO Cellular Component Annotations 2025	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10129
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.530298
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50224
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62857
RERF-LC-SQ1	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
htr3b	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47M-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA1	DepMap CRISPR Gene Dependency	1.0	2.0085
stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.371847
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901476
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65802
Iron uptake and transport(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
IRF1	ChEA Transcription Factor Targets	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Fourth ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.598
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296013
Sarcoma_SARC_TCGA-DX-AB2T-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AREB6	MotifMap Predicted Transcription Factor Targets	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28474
establishment of localization	GO Biological Process Annotations 2015	1.0	null
PPFIA4	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A772-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Vomiting	HuGE Navigator Gene-Phenotype Associations	1.0	null
CAMK2B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99206
HEC59	DepMap CRISPR Gene Dependency	1.0	3.69633
MZ1-PC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0186
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.867457
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3692
VCL	Pathway Commons Protein-Protein Interactions	1.0	null
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63838
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221521
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02392
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62286
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04809
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ergoloid mesylate	DrugBank Drug Targets	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80962
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6819
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29807
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040166
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.802494
TTN	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250627
serotonin-activated cation-selective channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02024
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01614
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7882
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5177
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.785
RMND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16076
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3294
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980401
DOLASETRON	DGIdb Drug Targets 2026	1.0	0.588133
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
Fibromyalgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
Motion sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproduction	GAD High Level Gene-Disease Associations	1.0	0.293278
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1532
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866624
Adrenocortical carcinoma_ACC_TCGA-OR-A5KW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76526
functional gastric disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.633563
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997489
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
DES	Pathway Commons Protein-Protein Interactions	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71219
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985965
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.624032
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.2466
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886467
vomiting	GeneRIF Biological Term Annotations	1.0	null
polymorphism	GeneRIF Biological Term Annotations	1.0	null
plexus	GeneRIF Biological Term Annotations	1.0	null
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
haloperidol	GeneRIF Biological Term Annotations	1.0	null
Opioid-Related Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
neuron projection	GO Cellular Component Annotations 2023	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.866
ABHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90799
CBX2	ENCODE Transcription Factor Targets	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	3.58429
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35769
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16173
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30391
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900896
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996345
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.277
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03237
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.49241
SLC39A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34239
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.289
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19432
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
channel activity	GO Molecular Function Annotations 2015	1.0	null
Plasma membrane signaling receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.071
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7518
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40381
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65802
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26139
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4355
KNS62	CCLE Cell Line Gene CNV Profiles	1.0	1.33709
Rectum adenocarcinoma_READ_TCGA-F5-6811-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX1A	Pathway Commons Protein-Protein Interactions	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
TPM3	Pathway Commons Protein-Protein Interactions	1.0	null
Tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976573
submucosal	GeneRIF Biological Term Annotations	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960518
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.79899
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9696
Neurotransmitter-gated ion-channel transmembrane domain	InterPro Predicted Protein Domain Annotations	1.0	null
obsessive-compulsive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	551.886
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5709
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9266
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3953
KNS81	DepMap CRISPR Gene Dependency	1.0	3.8452
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.697248
hsa-miR-4656	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Chronic closed-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6557
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTA2	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Taste transduction	KEGG Pathways 2026	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052064
SKHEP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45398
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18589
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8749
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.73196
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APOBEC3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0602
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940399
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44733
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06358
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48992
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
Familial adult myoclonic epilepsy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44653
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35769
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.922
Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.57459
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.914246
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4775
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	184.527
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35906
Enteric nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5307
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12772
hsa-miR-4481	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.994792
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2369	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYT5	Pathway Commons Protein-Protein Interactions	1.0	null
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83656
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9499
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5911
hsa-miR-4722-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
hsa-miR-3918	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.338
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868624
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3503
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956441
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.713625
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUDHL4	DepMap CRISPR Gene Dependency	1.0	2.02445
hsa-miR-544	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6823-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.464
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.1525
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76397
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066814
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_20_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.81926
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurotransmitter receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.611
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.28698
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
T47D	CCLE Cell Line Gene CNV Profiles	1.0	1.52822
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0042
ZIMELDINE HYDROCHLORIDE	DGIdb Drug Targets 2026	1.0	0.207576
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938788
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.3758
HMGN1_02_79	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63743
inorganic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
bodies	GeneRIF Biological Term Annotations	1.0	null
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864861
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040197
TROPISETRON	DGIdb Drug Targets 2026	1.0	0.271446
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17485
AMISULPRIDE	DGIdb Drug Targets 2026	1.0	0.135723
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05985
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979663
ZNF256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54893
RAB3A	Pathway Commons Protein-Protein Interactions	1.0	null
PPFIA2	Pathway Commons Protein-Protein Interactions	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	2.27972
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09646
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.491791
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.75564
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.863046
HDAC6	ENCODE Transcription Factor Targets	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91154
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18149
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RASGRP4	Pathway Commons Protein-Protein Interactions	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5452
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
Conduct disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.17985
PACADD161	DepMap CRISPR Gene Dependency	1.0	3.27758
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12261
SP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834756
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9751
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68115
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36662
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03501
biological_process	GO Biological Process Annotations 2015	1.0	null
RASGRF1	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64352
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A193-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4138
hsa-miR-3914	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Gut wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.704458
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.6388
Sarcoma_SARC_TCGA-K1-A6RU-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obsessive-Compulsive Disorder	DisGeNET Gene-Disease Associations	1.0	null
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.977
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44669
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-323b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2792
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059051
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07284
assessed	GeneRIF Biological Term Annotations	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37047
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217762
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99206
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87157
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
other	GAD High Level Gene-Disease Associations	1.0	0.293278
MYL3	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918882
nausea; pregnancy complications	GAD Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8515-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SP-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Familial adult myoclonic epilepsy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.842572
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834814
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-500a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43X-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Circumventricular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.569
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.091
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Neuronal System	Reactome Pathways 2024	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78639
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.37957
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
WM88	DepMap CRISPR Gene Dependency	1.0	5.03845
BFTC-905	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.817
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.73259
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04021
Y79	DepMap CRISPR Gene Dependency	1.0	2.07324
SORBS1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60009
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.87011
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0994
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colo-320 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870635
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.36783
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16883
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.412
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.097
DDP-225	DGIdb Drug Targets 2026	1.0	0.588133
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079702
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	2.56188
NCI-H716	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1889
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC4	DepMap CRISPR Gene Dependency	1.0	2.71854
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34104
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
TNNT2	Pathway Commons Protein-Protein Interactions	1.0	null
Esophageal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.571
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955785
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
large	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830637
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
l45	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
Mean platelet volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.3
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7CZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
serotonin-gated monoatomic cation-selective channel activity	GO Molecular Function Annotations 2023	1.0	null
htr3e	GeneRIF Biological Term Annotations	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37739
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.75713
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RVH421	DepMap CRISPR Gene Dependency	1.0	4.3511
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18898
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-WK-A8XO-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055202
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_8_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04704
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29678
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29T-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A6BG-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKCZ	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71U-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASGRF2	Pathway Commons Protein-Protein Interactions	1.0	null
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
coexpressed	GeneRIF Biological Term Annotations	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2258
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3754
Psychiatric Status Rating Scales	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0711
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RENZAPRIDE	DGIdb Drug Targets 2026	1.0	0.588133
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
TNNI1	Pathway Commons Protein-Protein Interactions	1.0	null
Antisocial personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59958
TMOD1	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991706
POLR3A	ENCODE Transcription Factor Targets	1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
MYBPC3	Pathway Commons Protein-Protein Interactions	1.0	null
SLR26	DepMap CRISPR Gene Dependency	1.0	2.79243
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.90383
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null